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In order to comprehensively evaluate and analyze the effectiveness of various heuristic intelligent optimization algorithms, this research employed particle swarm optimization, wind driven optimization, grey wolf optimization, and one-to-one-based optimizer as the basis. It applied 22 benchmark test functions to conduct a comparison and analysis of performance for these algorithms, considering descriptive statistics such as convergence speed, accuracy, and stability. Additionally, time and space complexity calculations were employed, alongside the nonparametric Friedman test, to further assess the algorithms. Furthermore, an investigation into the impact of control parameters on the algorithms' output was conducted to compare and analyze the test results under different algorithms. The experimental findings demonstrate the efficacy of the aforementioned approaches in comprehensively analyzing and comparing the performance on different types of intelligent optimization algorithms. These results illustrate that algorithm performance can vary across different test functions. The one-to-one-based optimizer algorithm exhibited superior accuracy, stability, and relatively lower complexity. [ABSTRACT FROM AUTHOR]

A series of CoFeB/Ta bilayer nano-thin films was fabricated on Si substrate using magnetron sputtering at room temperature. The temperature-and thickness-dependent dynamic magnetic properties of these films were investigated in detail using commercialized coplanar waveguide ferromagnetic resonance technique. The results showed that the Gilbert damping constant of bilayer films was monotonically decreases with the increase of temperature and thickness within certain range. We considered that the reasons for enhanced damping for the thinner magnetic films were derived from spin-pumping effect, two-magnon scatter, and magnetic dead layer. From thickness-dependent data, the surface/interface anisotropy constant, bulk damping contribution, and surface/interface damping contribution were obtained. Our results indicated that the bilayer films had perpendicular anisotropy when the CoFeB thickness was less than 1.38 nm. The results suggested that the influence of Ta on the dynamic properties of magnetic films cannot be ignored. The simplest stack structure of films was beneficial to understand the physical mechanism clearly. [ABSTRACT FROM AUTHOR]

A series of soft magnetic granular FeCoSiO films is fabricated using radio frequency magnetron sputtering under pure argon ambient conditions. The magnetic, high-frequency, and microwave noise suppression characteristics of these thin films are studied in detail. By using microwave probe station, integrated-type electromagnetic noise suppressors based on a coplanar waveguide transmission line and incorporated with a SiO 2 dielectric and a granular FeCoSiO magnetic thin film with excellent high frequency and soft magnetic properties are investigated. The relationship between transmission properties of electromagnetic noise suppressors and magnetic characteristics of FeCoSiO magnetic thin films were studied. The experimental values of the loss peak frequencies agree well with the calculated ferromagnetic resonant frequency, which considers the demagnetizing field. The results indicate that the main loss mechanism of the integrated devices is the ferromagnetic resonance, but not the L – C resonance. The FeCoSiO magnetic films are considered to be promising as ideal candidate materials for electromagnetic noise suppressor. [ABSTRACT FROM AUTHOR]

Flat plates and cylindrical shells are commonly used in large equipment. To locate the low-velocity impact points in these structures, this study proposes an error-index-based algorithm for impact localization. The time of arrival of an impact-generated A0 Lamb waves was first estimated based on the energy of the signal. Equations for calculating the error indices were proposed for flat-plate and cylindrical shell structures, and the probability distribution functions of the impact points are constructed for visual localization. The impact test results on a flat plate and cylindrical shell indicated that, compared to the Morlet wavelet method, the proposed algorithm improved the mean relative error of impact point localization on the flat plate by 0.22%, 15.64%, and 15.26% under three different noise conditions, respectively (i.e., no noise, and SNR = 5 and 0 dB). For the cylindrical shell, the mean relative error of impact localization improved by 1.8%, 3.97%, and 28.12% under the three conditions, respectively. The results indicated that the proposed localization algorithm can accurately locate the impact points on a flat plate and cylindrical shell, even under strong background noise conditions, providing a reference for future research on locating low-velocity impact points in large equipment. [ABSTRACT FROM AUTHOR]

• A composite lattice is proposed to combine advantage of auxetics and polyurea. • An abnormal hat-shape distortion opposite to impact direction of backplate is found. • The displacement time history of backplate center presents the shape of the letter N. • The failure modes of the auxetic cells and their distribution are revealed. • The dynamic mode of the auxetic sandwich panel subjected to explosion is presented. A series of air explosion experiments were carried out on the 3D polyurea-coated auxetic lattice sandwich panels in order to combine the advantages of auxetic materials and polyurea. The deformation, dynamic strain, and acceleration of the front and back plate were obtained. The results show that the dynamic response of the 3D polyurea-coated auxetic lattice sandwich panel could be divided into four stages: the shock wave action stage, the auxetic effect stage, the overall deformation stage, and the oscillation stage. The "N" type displacement time history of the back plate center due to the auxetic effect is found through the experiments. It is also found that the concave "hat-shaped" deformation mode of the back plate is opposite to the impact direction. This anomalous deformation mode is of great significance for impact protection. Finally, three dynamic response mode of the 3D polyurea-coated auxetic lattice sandwich panel subjected to air explosion is revealed. This study could provide a reference for the shock resistance design of structures. [ABSTRACT FROM AUTHOR]

Future machine learning (ML) powered applications, such as autonomous driving and augmented reality, involve training and inference tasks with timeliness requirements and are communication- and computation-intensive, which demands the edge learning framework. The real-time requirements drive us to go beyond accuracy for ML. In this article, we introduce the concept of timely edge learning, aiming to achieve accurate training and inference while minimizing the communication and computation delay. We discuss key challenges and propose corresponding solutions from data, model, and resource management perspectives to meet the timeliness requirements. In particular, for edge training, we argue that the total training delay rather than rounds should be considered, and propose data or model compression, and joint device scheduling and resource management schemes for both centralized training and federated learning systems. For edge inference, we explore the dependency between accuracy and delay for communication and computation, and propose dynamic data compression and flexible pruning schemes. Two case studies show that the timeliness performance, including the training accuracy under a given delay budget and the completion ratio of inference tasks within deadline, are highly improved with the proposed solutions. [ABSTRACT FROM AUTHOR]

Background: Because the incidence of endometrial cancer has been increasing every year, it is important to identify an effective screening method for it. The endometrial cytology test (ECT) is considered to be the more acceptable technique compared to invasive endometrial sampling. Methods: The study followed the Priority Reporting Project for Systematic Evaluation and Meta-Analysis (PRISMA-DTA) protocol. This systematic rating searched EMBASE and Web of Science databases for studies on ECT for endometrial cancer from the databases' dates of inception to 30 September 2022. All literature screening and data extraction were performed by two researchers, while the methodological quality of the included studies was assessed against defined inclusion criteria. And a third researcher resolves the disagreements. Results: Twenty-six studies were eventually included in this final analysis. Meta-analysis results showed that the diagnostic accuracy characteristics of ECT for endometrial cancer were as follows: combined sensitivity = 0.84 [95% confidence interval (CI) (0.83–0.86)], combined specificity = 0.98 [95% CI (0.98–0.98)], combined positive likelihood ratio = 34.65 [95% CI (20.90–57.45)], combined negative likelihood ratio = 0.21 [95% CI (0.15–0.30)], and area under the summary receiver operating characteristic curve = 0.9673. Conclusions: ECT had the ability to detect endometrial cancer with strong specificity, although some studies have demonstrated significant differences in sensitivity. [ABSTRACT FROM AUTHOR]

To explore the association between the single nucleotide polymorphism (SNP) of leptin receptor (LEPR) gene and the susceptibility to osteoporosis (OP) among Chinese Mulao people. A total of 738 people were involved. Bone mineral density (BMD) was examined by calcaneus ultrasound attenuation measurement. Six SNPs of LEPR were detected. The genotypes, allele frequencies, linkage disequilibrium, and haplotype were analyzed. BMD decreased with age and males had higher BMD than women. The proportion of normal bone mass decreased with age, and morbidity of OP increased. Three out of six SNPs showed a difference between OP and normal group. Individuals with AA genotype of rs1137100 in OP group outnumber the normal group, AA increased the risk of OP. In rs2767485, CT increased the risk of OP, C allele may be susceptible to OP. TT genotype of rs465555 was susceptible genotype of OP, T locus may be associated with OP. Strong linkage disequilibrium was detected among rs1137100, rs1137101, and rs4655555. Four haplotypes were constructed, among which, AACGCT and GGTGTA increased the risk of OP by 3.9 and 4.2 times, respectively, whereas, GGCGTA reduced 74% of OP susceptibility. The rs1137100, rs2767485, and rs465555 of LEPR were associated with OP in Chinese Mulao people. [ABSTRACT FROM AUTHOR]

Objective: To determine whether nerve fibers can be detected in the endometrium and myometrium in women with painful uterine fibroids and adenomyosis.Design: A retrospective immunohistochemical study.Setting: An academic training hospital.Patient(s): Thirty-seven women with uterine fibroids and 29 women with adenomyosis.Intervention(s): Histologic sections of contiguous endometrial and myometrial tissues were stained immunohistochemically using the highly specific polyclonal rabbit antiprotein gene product 9.5 (PGP9.5) and monoclonal mouse antineurofilament protein (NF).Main Outcome Measure(s): Results were determined through immunohistochemical staining using PGP9.5 and NF.Result(s): We detected PGP9.5-immunoactive nerve fibers in the functional layer of the endometrium in women with pain but not in women without pain. PGP9.5-immunoactive nerve fiber density in the basal layer of the endometrium or myometrium significantly increased in women with pain, however, PGP9.5-immunoactive nerve fiber density had no statistical differences between women with adenomyosis and uterine fibroids. We identified NF-immunoactive nerve fibers in the basal layer of the endometrium and myometrium in women with adenomyosis and uterine fibroids, but found no significant differences.Conclusion(s): These results suggest that PGP9.5-immunoactive nerve fibers appearing in the endometrium and myometrium of women with painful adenomyosis and uterine fibroids may play a role in pain generation in these two disorders. [ABSTRACT FROM AUTHOR]

A novel living biocomposite was engineered to boost environmental Cr(VI) remediation. Photosensitive biohybrids were firstly configured through an inward-to-outward assembly of NH 2 -doped carbon dots (NCDs), polydopamine (PDA) and wild Shewanella oneidensis MR-1 cells to generate microbial-photoreduction of Cr(VI) at the nanoscale. Then, biohybrid-derived biofilms were implanted onto the surface of melamine foam (MF) through an in-situ polypyrrole (PPy)-heterojunction to form highly conductive living MF/PPy/biohybrid biocomposites at a macroscale. Bacterial biomass immobilized onto the surface of MF and the efficacy of related biocomposites for Cr(VI) reduction increased with increasing pyrrole (PY) monomer concentrations (0.15 → 0.60 mL). In a 50 mg/L-Cr(VI) reduction system conducted under visible light illumination, biocomposites treated with 0.60 mL PY monomer displayed the highest Cr(VI) reduction efficiency (100%) with the shortest reaction time (24 h) during the first reduction cycle and significantly outperformed other biocomposite formulations over longer time periods (36–72 h). The living biocomposites exhibited an outstanding recyclability (>4 cycles) in subsequent reduction cycles. Overall, a reliable amalgamation of all living/non-living components integrated into the biocomposite ensured an efficient biocatalyst framework for Cr(VI) reduction and recyclable use. [Display omitted] • Biocomposites are fabricated with photosensitive biohybrids, polypyrrole and melamine foam through in-situ heterojunction. • Living biocomposites create a reliable and efficient biocatalyst framework for Cr(VI) reduction. • Catalytic efficacy of the biocomposite increased with the amount of polypyrrole wrapped onto the composite. • The living biocomposite displays an outstanding recyclability in dynamic Cr(VI) reduction cycles. • Living biocomposites represent an advanced biocatalyst for use in Cr(VI) remediation. [ABSTRACT FROM AUTHOR]

Objective Idiopathic inflammatory myositis-associated interstitial lung disease (IIM-ILD) significantly increases morbidity and mortality. Lung ultrasound B-lines and Krebs von den Lungen-6 (KL-6) are identified as new sonographic and serum markers of ILD, respectively. The aim of our work was to assess the role of B-lines and KL-6 as markers of the severity of IIM-ILD. For this purpose, the correlation among B-lines score, serum KL-6 levels, high-resolution CT (HRCT) score, and pulmonary function tests were investigated in IIM-ILD patients. Methods Thirty-eight patients with IIM-ILD underwent chest HRCT scans, lung ultrasound and pulmonary function tests (independently performed within 1 week) examination. To assess severity and extent of ILD at HRCT, the Warrick score was used. The B-lines score denoting the extension of ILD was calculated by summing the number of B-lines on a total of 50 scanning sites. Serum KL-6 levels (U/ml) was measured by chemiluminescent enzyme immunoassay. Results A significant correlation was found between the B-lines score and serum KL-6 levels (r  = 0.43, P  < 0.01), and between the Warrick score and serum KL-6 levels (r  = 0.45, P  < 0.01). A positive correlation between B-lines score and the Warrick score (r  = 0.87, P  < 0.0001) was also confirmed. Both B-lines score and KL-6 levels inversely correlated to diffusion capacity for carbon monoxide (r  = −0.77, P  < 0.0001 and r  = −0.42, P  < 0.05, respectively) and total lung capacity (r  = −0.73, P  < 0.0001 and r  = −0.36, P  < 0.05, respectively). Moreover, B-lines correlated inversely with forced vital capacity (r  = −0.73, P  < 0.0001), forced expiratory volume in 1 s (r  = −0.69, P  < 0.0001). Conclusion B-lines score and serum KL-6 levels correlate with HRCT findings and pulmonary function tests, supporting their use as measures of IIM-ILD severity. [ABSTRACT FROM AUTHOR]

To determine whether patients with endometriosis have altered levels of pigment epithelium–derived factor (PEDF) in peritoneal fluid, concentrations of PEDF in peritoneal fluid collected from 42 patients with endometriosis and 30 patients without endometriosis were measured with enzyme-linked immunosorbent assay. We detected significantly lower levels of peritoneal fluid PEDF in patients with endometriosis compared with patients without endometriosis, suggesting that peritoneal fluid PEDF plays a role in the pathogenesis of this disorder. [ABSTRACT FROM AUTHOR]

To determine whether nerve fibers in the functional layer endometrium are caused by an endometriosis itself or a common symptom of pain, endometrial tissues from 30 women with endometriosis, 40 women with adenomyosis, 41 women with uterine fibroids, and 47 endometriosis women with adenomyosis were stained immunohistochemically using the highly specific polyclonal rabbit antiprotein gene product 9.5 (PGP9.5) and monoclonal mouse antineurofilament protein. We demonstrated PGP9.5-immunoactive nerve fibers in the functional layer of endometrium in women with pain symptoms, but not in women without pain symptoms, whether the women had endometriosis, adenomyosis, uterine fibroids, or endometriosis with adenomyosis, suggesting a role of PGP9.5-immunoactive nerve fibers in the functional layer of the endometrium playing in pain generation in these disorders. [ABSTRACT FROM AUTHOR]

A series of (Ni 1− x Co x ) 2 MnGe and (Ni 0.2 Co 0.8 ) 2 Mn 1+ y Ge 1− y bulk X 2 YZ -type full Heusler alloys were synthesized by arc melting. Our results show that the structure of the (Ni 0.2 Co 0.8 ) 2 Mn 1+ y Ge 1− y alloys evolved from hexagonal Ni 2 In-type paramagnetic phase, and the cubic L 2 1 ferromagnetic phase evolved to the cubic B 2 ferrimagnetic one gradually with the increase of y from −0.8 to 0.8. In addition, the structure of the (Ni 1− x Co x ) 2 MnGe alloys evolved from the L 2 1 +Ni 5 Mn 4 Ge 3 impurity phase to the pure L 2 1 ferromagnetic one with the increase of x from 0 to 1.0. Magnetic tests indicated that ferromagnetic coupling occurred between Ni X /Co X and Mn Y ions (i.e., Ni, Co, and Mn ions in X , X , and Y sites, respectively) and antiferromagnetic coupling between Ni X /Co X and Mn Z ions (i.e., Mn ions in Z sites) for the L 2 1 structure of the alloys. High-resolution transmission-electron-microscopy studies confirmed the Heusler L 2 1 structure of (Ni 0.2 Co 0.8 ) 2 MnGe alloys, and revealed that Ni ions repelled each other in the Co-rich (Ni 1− x Co x ) 2 MnGe alloy, and it brought out the secondary phase in the Ni-rich (Ni 1− x Co x ) 2 MnGe alloy. Ferromagnetic resonance results showed that the Landé g factor for the L 2 1 (Ni 0.2 Co 0.8 ) 2 MnGe alloys was 2.17. However, it was only 2.04 for the (Ni 0.2 Co 0.8 ) 2 Mn 0.6 Ge 1.4 alloy due to its hexagonal crystal field. The large damping coefficient of 0.22 for the L 2 1 (Ni 0.2 Co 0.8 ) 2 MnGe alloy probably originated from the few antiferromagnetic-coupling Mn atoms. [ABSTRACT FROM AUTHOR]

The purinergic receptor P2X ligand-gated ion channel 3 (P2X3) is crucially involved in peripheral nociceptive processes of somatic and visceral pain. Endometriosis pain is considered as a kind of inflammatory and neuropathic pain. However, whether P2X3 is involved in endometriosis pain has not been reported up to date. Here, we aimed to determine whether P2X3 expression in endometriotic lesions is involved in endometriosis pain, which is regulated by inflammatory mediators through extracellular regulated protein kinases (ERK) signalling pathway. We found that P2X3 expressions in endometriosis endometrium and endometriotic lesions were both significantly higher as compared with control endometrium (P<0.05), and both positively correlated with pain (P<0.05). The expression levels of phosphorylated –ERK (p-ERK), phosphorylated-cAMP-response element binding protein (p-CREB), and P2X3 in endometriotic stromal cells (ESCs) were all significantly increased in comparison to the initial levels after treated with interleukin (IL)-1β (P<0.05) or adenosine triphosphate (ATP) (P<0.05), respectively, and did not increase after the ESCs were pre-treated with ERK1/2 inhibitor. Additionally, P2X3 and calcitonin gene related peptide (CGRP) were co-expressed in endometriotic lesions. These obtained results suggest that P2X3 might be involved in endometriosis pain signal transduction via ERK signal pathway. [ABSTRACT FROM AUTHOR]

The efficiency of aluminum tripolyphosphate (ATP) as inhibiting agents for carbon steel was studied in a carbonated concrete pore solution and mortars, respectively. The polarization resistance of the steel and the resistance of the concrete cover layer significantly increased when the content of ATP in mortars increasing. The electrochemical and surface analysis suggests that the stability of the passive film on carbon steel was enhanced by ATP; a tripolyphosphate adsorbed layer also formed on the surface of the steel. Consequently, the pitting corrosion of the steel was effective hindered by ATP both in the pore solution and mortars. [ABSTRACT FROM AUTHOR]

Background: Although nerve fibres are present in eutopic and ectopic endometrium, it is unclear whether they appear in ovarian endometriotic lesions. We investigated the presence of nerve fibres in ovarian endometriotic lesions and its correlation with clinical parameters in women with ovarian endometriosis.Methods: Histological sections of ovarian endometriotic lesions from 61 women with ovarian endometriosis (Stages II-IV) who underwent laparoscopic endometrioma cystectomy were stained immunohistochemically using a specific polyclonal rabbit anti-protein gene product 9.5 (PGP9.5) antibody to demonstrate myelinated and unmyelinated nerve fibres.Results: Nerve fibres stained with PGP9.5 were detected in ovarian endometriotic lesions in 31.1% of women, and most appeared in fibrotic interstitium of ovarian endometriotic lesions. The density of PGP9.5-immunoactive fibres in ovarian endometriotic lesions in women with pain symptoms (n = 35) was higher than in women with no pain symptoms (n = 26, P = 0.039), although the percentage (positive cases/total) of PGP9.5-positive fibres did not differ. In women with pain symptoms, PGP9.5-positive fibres appeared in 40.0% of cases and the density of PGP9.5-immunoactive fibres in ovarian endometriotic lesions was correlated with severity of pain symptoms (r = 0.466, P = 0.005). In women with no pain, PGP9.5-positive fibres were detected in only 5 (19.2%) women. Both the percentage and the density of PGP9.5-positive fibres in ovarian endometriotic lesions were associated with pelvic adhesions (chi2 = 6.833, P = 0.009; Z = 2.442, P = 0.015, respectively) but not with disease severity.Conclusions: PGP9.5-immunoactive nerve fibres in ovarian endometriotic lesions may be involved in the pathophysiology of pain generation and pelvic adhesion formation in women with ovarian endometriosis. [ABSTRACT FROM AUTHOR]