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Your search keyword '"Hydroxypropylmethylcellulose 4000"' showing total 3 results
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3 results on '"Hydroxypropylmethylcellulose 4000"'

1. Role of hydroxypropylmethylcellulose (HPMC 4000) in the protection of the polymorphs of Piroxicam extended release tablets

Author

A. Merah, A. Abidi, N. Chaffai, B. Bataille, and N. Gherraf

Subjects
Piroxicam, Polymorphism, Hydroxypropylmethylcellulose 4000, Crystallization, Extended release, Chemistry, QD1-999
Abstract

The present study deals with the influence of hydroxypropylmethylcellulose 4000 in the protection of Piroxicam polymorphs which could appear during the processes of formulation of extended release tablets. The physico-chemical tests and the dissolution profiles of polymorphs and tablets showed that the metolose incorporated in the tablets at a rate equivalent to 5% could possibly act doubly; initially by protecting the piroxicam polymorphism transition (form II) during compression, then modulating its in vitro release (extended release).

Published
2017
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2. Role of hydroxypropylmethylcellulose (HPMC 4000) in the protection of the polymorphs of Piroxicam extended release tablets

Author

N. Chaffai, Abdelali Merah, B. Bataille, Abdenabi Abidi, and Noureddine Gherraf

Subjects
Chemistry(all), Stereochemistry, Hydroxypropylmethylcellulose 4000, General Chemical Engineering, 02 engineering and technology, Piroxicam, 030226 pharmacology & pharmacy, lcsh:Chemistry, 03 medical and health sciences, 0302 clinical medicine, medicine, Polymorphism, GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries), ComputingMilieux_MISCELLANEOUS, Chemistry, General Chemistry, 021001 nanoscience & nanotechnology, Extended release, lcsh:QD1-999, Chemical Engineering(all), Crystallization, 0210 nano-technology, Extended release tablets, medicine.drug, Nuclear chemistry
Abstract

The present study deals with the influence of hydroxypropylmethylcellulose 4000 in the protection of Piroxicam polymorphs which could appear during the processes of formulation of extended release tablets. The physico-chemical tests and the dissolution profiles of polymorphs and tablets showed that the metolose incorporated in the tablets at a rate equivalent to 5% could possibly act doubly; initially by protecting the piroxicam polymorphism transition (form II) during compression, then modulating its in vitro release (extended release).

Published
2017
Full Text
View/download PDF

3. Role of hydroxypropylmethylcellulose (HPMC 4000) in the protection of the polymorphs of Piroxicam extended release tablets.

Author

Merah, A., Abidi, A., Chaffai, N., Bataille, B., and Gherraf, N.

Abstract

The present study deals with the influence of hydroxypropylmethylcellulose 4000 in the protection of Piroxicam polymorphs which could appear during the processes of formulation of extended release tablets. The physico-chemical tests and the dissolution profiles of polymorphs and tablets showed that the metolose incorporated in the tablets at a rate equivalent to 5% could possibly act doubly; initially by protecting the piroxicam polymorphism transition (form II) during compression, then modulating its in vitro release (extended release). [ABSTRACT FROM AUTHOR]

Published
2017
Full Text
View/download PDF

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