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30 results on '"Iberer, Florian"'

1. Immediate and Long-Term Effects of Hyperbaric Oxygenation in Patients with Long COVID-19 Syndrome Using SF-36 Survey and VAS Score: A Clinical Pilot Study

Author

Lindenmann, Joerg, primary, Porubsky, Christian, additional, Okresa, Lucija, additional, Klemen, Huberta, additional, Mykoliuk, Iurii, additional, Roj, Andrej, additional, Koutp, Amir, additional, Kink, Eveline, additional, Iberer, Florian, additional, Kovacs, Gabor, additional, Krause, Robert, additional, Smolle, Josef, additional, and Smolle-Juettner, Freyja Maria, additional

Published
2023
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7. Computerized heart allograft-recipient monitoring: a multicenter study

Author

Grasser, Barbara, Iberer, Florian, Schreier, Günter, Kastner, Peter, Schaffellner, Silvia, Kniepeiss, Daniela, Kleinert, Reinhold, Mahaux, Veronique, Demoulin, Jean Claude, Nägele, Herbert, Rödiger, Wilfried, Laufer, Günther, Grimm, Michael, Zuckermann, Andreas, Wasler, Andre, Prenner, Günther, and Tscheliessnigg, Karl-Heinz

Published
2003
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20. Immunohistochemical and radiological characterization of wound healing in porcine liver after radiofrequency ablation

Author

Stadlbauer, Vanessa, Lang-Olip, Ingrid, Leber, Bettina, Mayrhauser, Ursula, Koestenbauer, Sonja, Tawdrous, Monika, Moche, Michael, Sereinigg, Michael, Seider, Daniel, Iberer, Florian, Wiederstein-Grasser, Iris, Horst Portugaller, Rupert, and Stiegler, Philipp

Subjects
Healthy pig, surgical procedures, operative, Liver, 6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología [CDU], Radiofrequency ablation, Wound healing, therapeutics, Immunohistochemistry
Abstract

Background: Radiofrequency ablation (RFA) is a minimal invasive therapeutic option for patients with hepatocellular carcinoma or liver metastases. We investigated RFA-induced cellular changes in the liver of pigs. Material and Methods: Healthy pigs (n=18) were sacrificed between day 0 and 3 months after RFA. The wound healing process was evaluated by computed tomography (CT), chromotrope anilinblue (CAB) staining of large-scale and standard tissue sections. Immunohistochemistry (IHC) for heat shock protein 70, Caspase-3, Ki67, Reelin, Vinculin, Vimentin and αSMA was perfomed. Results: One day after RFA, CAB staining showed cell damage and massive hyperaemia. All IHC markers were predominantly expressed at the outer borders of the lesion, except Reelin, which was mainly detected in untreated liver regions. By staining for Hsp70, the heat stress during RFA was monitored, which was most distinct 1-2 days after RFA. CT revealed decreased lesion size after one week. Development of a Vimentin and α-SMA positive fibrotic capsule was observed. Conclusion: In the early phase signs of cell damage, apoptosis and proliferation are dominant. Reduced expression of Reelin suggests a minor role of hepatic stellate cells in the RFA zone. After one week myofibroblasts become prominent and contribute to the development of the fibrotic capsule. This elucidates the pathophysiology of RFA and could contribute to the future optimization of RFA procedures.

Published
2016

21. StudentInnen arbeiten an PatientInnen - Ein Widerspruch? Praktische Ausbildung der Studierenden im 6. Studienjahr an der Klinischen Abteilung für Thorax- und Hyperbare Chirurgie der Universitätsklinik für Chirurgie Graz, MUG

Author

Matzi, Veronika, Wagner, Doris, Manhal, Simone, Caluba, Hans-Christian, Iberer, Florian, and Smolle-Jüttner, Freyja

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

[for full text, please go to the a.m. URL], 15. Grazer Konferenz – Qualität der Lehre: Teaching and Learning – expanding our resources

Published
2012
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22. Chirurgie und OSKE - ein Widerspruch?

Author

Kniepeiss, Daniela, Wagner, Doris, Manhal, Simone, Tscheliessnigg, Karl-Heinz, and Iberer, Florian

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

[for full text, please go to the a.m. URL], 14. Grazer Konferenz – Qualität der Lehre: New Horizons in Teaching and Learning

Published
2010

23. Effectiveness of porcine dermal collagen in giant hernia closure in patients with deleterious fascia constitution after orthotopic liver transplantation

Author

Werkgartner, Georg, primary, Cerwenka, Herwig, additional, Rappl, Thomas, additional, Kniepeiss, Daniela, additional, Kornprat, Peter, additional, Iberer, Florian, additional, Bacher, Heinz, additional, Wagner, Mathias, additional, Mischinger, Hans J., additional, and Wagner, Doris, additional

Published
2014
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24. Gene expression in vascular calcification: are there differences between atherosclerotic changes and media sclerosis?

Author

Schweighofer, Natascha, primary, Aigelsreiter, Ariane, additional, Graf-Rechberger, Martina, additional, Hacker, Nicole, additional, Iberer, Florian, additional, Kniepeiss, Daniela, additional, Wagner, Doris, additional, Stiegler, Philipp, additional, Gutschi, Jurgen, additional, Trummer, Olivia, additional, Sinner, Frank, additional, Pieber, Thomas, additional, Muller, Helmut, additional, and Obermayer-Pietsch, Barbara, additional

Published
2014
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26. Oxidative stress and apoptosis in a pig model of brain death (BD) and living donation (LD)

Author

Stiegler, Philipp, primary, Sereinigg, Michael, additional, Puntschart, Andreas, additional, Bradatsch, Andrea, additional, Seifert-Held, Thomas, additional, Wiederstein-Grasser, Iris, additional, Leber, Bettina, additional, Stadelmeyer, Elke, additional, Dandachi, Nadia, additional, Zelzer, Siglinde, additional, Iberer, Florian, additional, and Stadlbauer, Vanessa, additional

Published
2013
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27. Reply

Author

Wagner, Doris, primary, Kniepeiss, Daniela, additional, Iberer, Florian, additional, Fahrleitner-Pammer, Astrid, additional, Kornprat, Peter, additional, and Tscheliessnigg, Karlheinz, additional

Published
2010
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28. Transplant International Thanks the Guest Editors.

Author

Berlakovich, Gabriela, Böhmig, George, Grimm, Michael, Iberer, Florian, Klauser, Renate, Oberbauer, Rainer, Säemann, Marcus, Soliman, Thomas, Steininger, Rudolf, Wisser, Wilfred, and Ziabinger, Gerhard

Subjects
TRANSPLANTATION of organs, tissues, etc., PERIODICALS, EDITORS, GRATITUDE, CONFERENCES & conventions
Abstract

The article presents the authors' gratitude to guest editors of the periodical "Transplant International." It appreciates the significant contribution of the guest editors for their critical help in the editorial processing of the papers submitted at the 11th Congress of the European Society for Organ Transplantation in Venice, Italy in 2003. All of these papers underwent the full review process and were critically evaluated by the Guest Editors.

Published
2004
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29. Cell to cell interactions influence sensitivity of liver cell lines during hyperthermia.

Author

Mayrhauser U, Stiegler P, Stadlbauer V, Koestenbauer S, Leber B, Konrad K, Iberer F, and Tscheliessnigg K

Subjects
Carcinoma, Hepatocellular metabolism, Carcinoma, Hepatocellular therapy, Cell Proliferation, Cells, Cultured, Coculture Techniques, Fibrosis metabolism, Hepatic Stellate Cells metabolism, Humans, Liver Neoplasms metabolism, Liver Neoplasms therapy, Carcinoma, Hepatocellular pathology, Cell Communication, Fibrosis pathology, Hepatic Stellate Cells pathology, Hyperthermia, Induced, Liver Neoplasms pathology
Abstract

Background: Thermal cancer therapy is used for hepatocellular carcinoma treatment. In this study we investigated the effect of hyperthermia on liver cells and compared data of our different cell culture fibrosis models (transwell vs. co-culture model)., Materials and Methods: The cell lines HepG2 and LX-1 were seeded in different numbers in transwells to simulate different grades of fibrosis and then heated from 55°C to 85°C for different time spans. Thereafter, metabolic activity was measured., Results: Heating at 65°C showed that the greater the number of LX-1 cells treated together with HepG2 cells the lower the metabolic activity of HepG2 cells was. Compared to our previous co-culture study, there were significantly different results in cell survival from 55°C to 75°C., Conclusion: The co-culture fibrosis model is more physiological than the transwell model because it allows a higher seeding density and a higher degree of cell to cell interactions. Therefore, it is more efficient for investigating the effect of hyperthermia on liver cells.

Published
2011

30. Effect of hyperthermia on liver cell lines: important findings for thermal therapy in hepatocellular carcinoma.

Author

Mayrhauser U, Stiegler P, Stadlbauer V, Koestenbauer S, Leber B, Konrad K, Iberer F, Portugaller RH, and Tscheliessnigg K

Subjects
Carcinoma, Hepatocellular metabolism, Carcinoma, Hepatocellular pathology, Coculture Techniques, Humans, Liver metabolism, Liver Neoplasms metabolism, Liver Neoplasms pathology, Tetrazolium Salts pharmacology, Thiazoles pharmacology, Tumor Cells, Cultured, Carcinoma, Hepatocellular therapy, Fever, Hot Temperature therapeutic use, Liver Neoplasms therapy
Abstract

Background: Hepatocellular carcinoma is the fifth most common malignant tumour, with a high mortality rate. This study aimed to investigate the effect of hyperthermia on HepG2 and LX-1 cell lines to gain more information on thermal treatment of liver tumours., Materials and Methods: The cell lines HepG2, LX-1 and their co-cultures were heated from 55°C to 85°C for different time spans. After heat exposure, metabolic activity was measured immediately, and after 24 h and 48 h using the 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium) (MTS) test to assess how many cells had survived heating., Results: Our results show highly significant differences between the temperature tolerance of HepG2 and LX-1 cells. Alone, HepG2 cells are most sensitive to heat-induced cell death, their sensitivity decreased with rising percentages of LX-1 cells in the co-culture., Conclusion: Our results suggest that the outcome of thermal cancer therapy is dependent on the temperature and the grade of fibrosis in the treated livers.

Published
2011

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