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1. Impact of malnutrition on mortality and neurological recovery of older patients with spinal cord injury

Author

Tamai, Koji, Terai, Hidetomi, Nakamura, Hiroaki, Yokogawa, Noriaki, Sasagawa, Takeshi, Nakashima, Hiroaki, Segi, Naoki, Ito, Sadayuki, Funayama, Toru, Eto, Fumihiko, Yamaji, Akihiro, Watanabe, Kota, Yamane, Junichi, Takeda, Kazuki, Furuya, Takeo, Yunde, Atsushi, Nakajima, Hideaki, Yamada, Tomohiro, Hasegawa, Tomohiko, Terashima, Yoshinori, Hirota, Ryosuke, Suzuki, Hidenori, Imajo, Yasuaki, Ikegami, Shota, Uehara, Masashi, Tonomura, Hitoshi, Sakata, Munehiro, Hashimoto, Ko, Onoda, Yoshito, Kawaguchi, Kenichi, Haruta, Yohei, Suzuki, Nobuyuki, Kato, Kenji, Uei, Hiroshi, Sawada, Hirokatsu, Nakanishi, Kazuo, Misaki, Kosuke, Kuroda, Akiyoshi, Inoue, Gen, Kakutani, Kenichiro, Kakiuchi, Yuji, Kiyasu, Katsuhito, Tominaga, Hiroyuki, Tokumoto, Hiroto, Iizuka, Yoichi, Takasawa, Eiji, Akeda, Koji, Takegami, Norihiko, Funao, Haruki, Oshima, Yasushi, Kaito, Takashi, Sakai, Daisuke, Yoshii, Toshitaka, Ohba, Tetsuro, Otsuki, Bungo, Seki, Shoji, Miyazaki, Masashi, Ishihara, Masayuki, Okada, Seiji, Imagama, Shiro, and Kato, Satoshi

Published
2024
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3. Characteristics of the cervical spine and cervical cord injuries in older adults with cervical ossification of the posterior longitudinal ligament

Author

Okuwaki, Shun, Funayama, Toru, Koda, Masao, Eto, Fumihiko, Yamaji, Akihiro, Yokogawa, Noriaki, Sasagawa, Takeshi, Ando, Kei, Nakashima, Hiroaki, Segi, Naoki, Watanabe, Kota, Nori, Satoshi, Takeda, Kazuki, Furuya, Takeo, Yunde, Atsushi, Nakajima, Hideaki, Yamada, Tomohiro, Hasegawa, Tomohiko, Terashima, Yoshinori, Hirota, Ryosuke, Suzuki, Hidenori, Imajo, Yasuaki, Ikegami, Shota, Uehara, Masashi, Tonomura, Hitoshi, Sakata, Munehiro, Hashimoto, Ko, Onoda, Yoshito, Kawaguchi, Kenichi, Haruta, Yohei, Suzuki, Nobuyuki, Kato, Kenji, Uei, Hiroshi, Sawada, Hirokatsu, Nakanishi, Kazuo, Misaki, Kosuke, Terai, Hidetomi, Tamai, Koji, Shirasawa, Eiki, Inoue, Gen, Kakutani, Kenichiro, Kakiuchi, Yuji, Kiyasu, Katsuhito, Tominaga, Hiroyuki, Tokumoto, Hiroto, Iizuka, Yoichi, Takasawa, Eiji, Akeda, Koji, Takegami, Norihiko, Funao, Haruki, Oshima, Yasushi, Kaito, Takashi, Sakai, Daisuke, Yoshii, Toshitaka, Ohba, Tetsuro, Otsuki, Bungo, Seki, Shoji, Miyazaki, Masashi, Ishihara, Masayuki, Okada, Seiji, Imagama, Shiro, and Kato, Satoshi

Published
2023
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4. Influence of the timing of surgery for cervical spinal cord injury without bone injury in the elderly: A retrospective multicenter study

Author

Nori, Satoshi, Watanabe, Kota, Takeda, Kazuki, Yamane, Junichi, Kono, Hitoshi, Yokogawa, Noriaki, Sasagawa, Takeshi, Ando, Kei, Nakashima, Hiroaki, Segi, Naoki, Funayama, Toru, Eto, Fumihiko, Yamaji, Akihiro, Furuya, Takeo, Yunde, Atsushi, Nakajima, Hideaki, Yamada, Tomohiro, Hasegawa, Tomohiko, Terashima, Yoshinori, Hirota, Ryosuke, Suzuki, Hidenori, Imajo, Yasuaki, Ikegami, Shota, Uehara, Masashi, Tonomura, Hitoshi, Sakata, Munehiro, Hashimoto, Ko, Onoda, Yoshito, Kawaguchi, Kenichi, Haruta, Yohei, Uei, Hiroshi, Sawada, Hirokatsu, Nakanishi, Kazuo, Misaki, Kosuke, Terai, Hidetomi, Tamai, Koji, Shirasawa, Eiki, Inoue, Gen, Kiyasu, Katsuhito, Iizuka, Yoichi, Takasawa, Eiji, Funao, Haruki, Kaito, Takashi, Yoshii, Toshitaka, Ishihara, Masayuki, Okada, Seiji, Imagama, Shiro, and Kato, Satoshi

Published
2024
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5. Preoperative factors affecting the two-year postoperative patient-reported outcome in single-level lumbar grade I degenerative spondylolisthesis

Author

Kanchiku, Tsukasa, Taguchi, Toshihiko, Sekiguchi, Miho, Toda, Naofumi, Hosono, Noboru, Matsumoto, Morio, Tanaka, Nobuhiro, Akeda, Koji, Hashizume, Hiroshi, Kanayama, Masahiro, Orita, Sumihisa, Takeuchi, Daisaku, Kawakami, Mamoru, Fukui, Mitsuru, Kanamori, Masahiko, Wada, Eiji, Kato, So, Hongo, Michio, Ando, Kei, Iizuka, Yoichi, Ikegami, Shota, Kawamura, Naohiro, Takami, Masanari, Yamato, Yu, Takahashi, Shinji, Watanabe, Kei, Takahashi, Jun, Konno, Shinichi, and Chikuda, Hirotaka

Published
2023
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6. Does surgery improve neurological outcomes in older individuals with cervical spinal cord injury without bone injury? A multicenter study

Author

Nori, Satoshi, Watanabe, Kota, Takeda, Kazuki, Yamane, Junichi, Kono, Hitoshi, Yokogawa, Noriaki, Sasagawa, Takeshi, Ando, Kei, Nakashima, Hiroaki, Segi, Naoki, Funayama, Toru, Eto, Fumihiko, Yamaji, Akihiro, Furuya, Takeo, Yunde, Atsushi, Nakajima, Hideaki, Yamada, Tomohiro, Hasegawa, Tomohiko, Terashima, Yoshinori, Hirota, Ryosuke, Suzuki, Hidenori, Imajo, Yasuaki, Ikegami, Shota, Uehara, Masashi, Tonomura, Hitoshi, Sakata, Munehiro, Hashimoto, Ko, Onoda, Yoshito, Kawaguchi, Kenichi, Haruta, Yohei, Suzuki, Nobuyuki, Kato, Kenji, Uei, Hiroshi, Sawada, Hirokatsu, Nakanishi, Kazuo, Misaki, Kosuke, Terai, Hidetomi, Tamai, Koji, Shirasawa, Eiki, Inoue, Gen, Kiyasu, Katsuhito, Iizuka, Yoichi, Takasawa, Eiji, Funao, Haruki, Kaito, Takashi, Yoshii, Toshitaka, Ishihara, Masayuki, Okada, Seiji, Imagama, Shiro, and Kato, Satoshi

Published
2022
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7. Differences in clinical characteristics of cervical spine injuries in older adults by external causes: a multicenter study of 1512 cases

Author

Yokogawa, Noriaki, Kato, Satoshi, Sasagawa, Takeshi, Hayashi, Hiroyuki, Tsuchiya, Hiroyuki, Ando, Kei, Nakashima, Hiroaki, Segi, Naoki, Funayama, Toru, Eto, Fumihiko, Yamaji, Akihiro, Nori, Satoshi, Yamane, Junichi, Furuya, Takeo, Yunde, Atsushi, Nakajima, Hideaki, Yamada, Tomohiro, Hasegawa, Tomohiko, Terashima, Yoshinori, Hirota, Ryosuke, Suzuki, Hidenori, Imajo, Yasuaki, Ikegami, Shota, Uehara, Masashi, Tonomura, Hitoshi, Sakata, Munehiro, Hashimoto, Ko, Onoda, Yoshito, Kawaguchi, Kenichi, Haruta, Yohei, Suzuki, Nobuyuki, Kato, Kenji, Uei, Hiroshi, Sawada, Hirokatsu, Nakanishi, Kazuo, Misaki, Kosuke, Terai, Hidetomi, Tamai, Koji, Shirasawa, Eiki, Inoue, Gen, Kakutani, Kenichiro, Kakiuchi, Yuji, Kiyasu, Katsuhito, Tominaga, Hiroyuki, Tokumoto, Hiroto, Iizuka, Yoichi, Takasawa, Eiji, Akeda, Koji, Takegami, Norihiko, Funao, Haruki, Oshima, Yasushi, Kaito, Takashi, Sakai, Daisuke, Yoshii, Toshitaka, Ohba, Tetsuro, Otsuki, Bungo, Seki, Shoji, Miyazaki, Masashi, Ishihara, Masayuki, Okada, Seiji, Imagama, Shiro, and Watanabe, Kota

Published
2022
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8. A multicenter study of 1-year mortality and walking capacity after spinal fusion surgery for cervical fracture in elderly patients

Author

Sasagawa, Takeshi, Yokogawa, Noriaki, Hayashi, Hiroyuki, Tsuchiya, Hiroyuki, Ando, Kei, Nakashima, Hiroaki, Segi, Naoki, Watanabe, Kota, Nori, Satoshi, Takeda, Kazuki, Furuya, Takeo, Yunde, Atsushi, Ikegami, Shota, Uehara, Masashi, Suzuki, Hidenori, Imajo, Yasuaki, Funayama, Toru, Eto, Fumihiko, Yamaji, Akihiro, Hashimoto, Ko, Onoda, Yoshito, Kakutani, Kenichiro, Kakiuchi, Yuji, Suzuki, Nobuyuki, Kato, Kenji, Terashima, Yoshinori, Hirota, Ryosuke, Yamada, Tomohiro, Hasegawa, Tomohiko, Kawaguchi, Kenichi, Haruta, Yohei, Seki, Shoji, Tonomura, Hitoshi, Sakata, Munehiro, Uei, Hiroshi, Sawada, Hirokatsu, Tominaga, Hiroyuki, Tokumoto, Hiroto, Kaito, Takashi, Iizuka, Yoichi, Takasawa, Eiji, Oshima, Yasushi, Terai, Hidetomi, Tamai, Koji, Otsuki, Bungo, Miyazaki, Masashi, Nakajima, Hideaki, Nakanishi, Kazuo, Misaki, Kosuke, Inoue, Gen, Kiyasu, Katsuhito, Akeda, Koji, Takegami, Norihiko, Yoshii, Toshitaka, Ishihara, Masayuki, Okada, Seiji, Aoki, Yasuchika, Harimaya, Katsumi, Murakami, Hideki, Ishii, Ken, Ohtori, Seiji, Imagama, Shiro, and Kato, Satoshi

Published
2022
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9. Primary epidural extra-osseous Ewing sarcoma/peripheral primitive neuroectodermal tumor of the cervical spine curatively treated by surgery and adjuvant chemoradiotherapy: A case report and review of the literature

Author

Ito, Shunsuke, Iizuka, Yoichi, Nishinome, Masahiro, Yanagawa, Takashi, Koshi, Hiromi, Tokue, Azusa, Mieda, Tokue, Takasawa, Eiji, Tsunoda, Daisuke, Ishiwata, Sho, Honda, Akira, Inomata, Kazuhiro, Tajika, Tsuyoshi, and Chikuda, Hirotaka

Published
2021
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10. Association Between Early Surgery and Postoperative Opioid Use in Patients With Lumbar Disc Herniation: A Propensity Score-Matching Analysis Using an Administrative Claims Database in Japan.

Author

Honda, Akira, Iizuka, Yoichi, Tokue, Mieda, Takasawa, Eiji, Ishiwata, Sho, Tomomatsu, Yusuke, Ito, Shunsuke, Inomata, Kazuhiro, Okada, Akira, Matsui, Hiroki, Yasunaga, Hideo, and Chikuda, Hirotaka

Subjects
SPINAL surgery, DATABASES, HERNIA, OPIOIDS, SURGERY, DELAYED diagnosis
Abstract

Study Design: Retrospective cohort study Objectives: This study aimed to investigate whether early surgery shortens the duration of opioid use in patients who underwent surgery with lumbar disc herniation. Methods: We extracted patients who underwent surgery at least 2 weeks after they were diagnosed with lumbar disc herniation between April 2014 and May 2021. Opioid use after surgery was compared between patients who underwent surgery within 90 days (early surgery group) and 90 days or later (late surgery group). Propensity-score-matching analysis and multivariable Cox hazard regression analysis with a restricted cubic spline model were conducted to evaluate the association between the timing of surgery and termination of opioid use after surgery. Results: A total of 1597 eligible patients were identified, with 807 (51%) in the early surgery group. In the propensity-score-matched cohort, the early surgery group had a significantly lower proportion of opioid use than the control group (28% vs 48%, percent difference −20%, P <.001). Multivariable Cox hazard regression analysis showed that early surgery was significantly associated with the earlier termination of opioid use (HR, 3.13; 95% CI, 1.97-4.97; P <.001). Restricted cubic spline model showed a monotonically decreased hazard ratio and decreased hazard ratio of.50 in patients who underwent surgery 111 days or later after the diagnosis. Conclusions: Early surgery, especially within 90 days, was associated with earlier opioid use termination after surgery. Regarding the duration of opioid use following surgery, surgical treatment may be preferable to perform within around 4 months after the diagnosis. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Early Versus Delayed Surgery for Elderly Traumatic Cervical Spinal Injury: A Nationwide Multicenter Study in Japan

Author

Segi, Naoki, primary, Nakashima, Hiroaki, additional, Ito, Sadayuki, additional, Yokogawa, Noriaki, additional, Sasagawa, Takeshi, additional, Watanabe, Kota, additional, Nori, Satoshi, additional, Funayama, Toru, additional, Eto, Fumihiko, additional, Nakajima, Hideaki, additional, Terashima, Yoshinori, additional, Hirota, Ryosuke, additional, Hashimoto, Ko, additional, Onoda, Yoshito, additional, Furuya, Takeo, additional, Yunde, Atsushi, additional, Ikegami, Shota, additional, Uehara, Masashi, additional, Suzuki, Hidenori, additional, Imajo, Yasuaki, additional, Uei, Hiroshi, additional, Sawada, Hirokatsu, additional, Kawaguchi, Kenichi, additional, Nakanishi, Kazuo, additional, Suzuki, Nobuyuki, additional, Oshima, Yasushi, additional, Hasegawa, Tomohiko, additional, Iizuka, Yoichi, additional, Tonomura, Hitoshi, additional, Terai, Hidetomi, additional, Akeda, Koji, additional, Seki, Shoji, additional, Ishihara, Masayuki, additional, Inoue, Gen, additional, Funao, Haruki, additional, Yoshii, Toshitaka, additional, Kaito, Takashi, additional, Kiyasu, Katsuhito, additional, Tominaga, Hiroyuki, additional, Kakutani, Kenichiro, additional, Sakai, Daisuke, additional, Ohba, Tetsuro, additional, Otsuki, Bungo, additional, Miyazaki, Masashi, additional, Murotani, Kenta, additional, Okada, Seiji, additional, Imagama, Shiro, additional, and Kato, Satoshi, additional

Published
2024
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12. Low Nutrition Before Injury Is A Risk Factor For Dysphagia In Older Patients With Cervical Spinal Cord Injury: Based On A Multicenter Data Of 707 Patients

Author

Segi, Naoki, primary, Nakashima, Hiroaki, additional, Ito, Sadayuki, additional, Ouchida, Jun, additional, Yokogawa, Noriaki, additional, Sasagawa, Takeshi, additional, Funayama, Toru, additional, Eto, Fumihiko, additional, Watanabe, Kota, additional, Nori, Satoshi, additional, Furuya, Takeo, additional, Yunde, Atsushi, additional, Terashima, Yoshinori, additional, Hirota, Ryosuke, additional, Nakajima, Hideaki, additional, Yamada, Tomohiro, additional, Hasegawa, Tomohiko, additional, Kawaguchi, Kenichi, additional, Haruta, Yohei, additional, Hashimoto, Ko, additional, Onoda, Yoshito, additional, Nakanishi, Kazuo, additional, Misaki, Kosuke, additional, Ikegami, Shota, additional, Uehara, Masashi, additional, Suzuki, Hidenori, additional, Imajo, Yasuaki, additional, Uei, Hiroshi, additional, Sawada, Hirokatsu, additional, Terai, Hidetomi, additional, Tamai, Koji, additional, Kuroda, Akiyoshi, additional, Inoue, Gen, additional, Suzuki, Nobuyuki, additional, Kato, Kenji, additional, Akeda, Koji, additional, Takegami, Norihiko, additional, Iizuka, Yoichi, additional, Oshima, Yasushi, additional, Tonomura, Hitoshi, additional, Kiyasu, Katsuhito, additional, Funao, Haruki, additional, Yoshii, Toshitaka, additional, Ishihara, Masayuki, additional, Kaito, Takashi, additional, Seki, Shoji, additional, Kakutani, Kenichiro, additional, Tominaga, Hiroyuki, additional, Ohba, Tetsuro, additional, Sakai, Daisuke, additional, Otsuki, Bungo, additional, Miyazaki, Masashi, additional, Okada, Seiji, additional, Imagama, Shiro, additional, and Kato, Satoshi, additional

Published
2024
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13. Comparative Analysis of Characteristics of Lower- and Mid-Cervical Spine Injuries in the Elderly

Author

Segi, Naoki, primary, Nakashima, Hiroaki, additional, Ito, Sadayuki, additional, Ouchida, Jun, additional, Yokogawa, Noriaki, additional, Sasagawa, Takeshi, additional, Furuya, Takeo, additional, Yunde, Atsushi, additional, Funayama, Toru, additional, Eto, Fumihiko, additional, Watanabe, Kota, additional, Nori, Satoshi, additional, Ikegami, Shota, additional, Uehara, Masashi, additional, Hashimoto, Ko, additional, Onoda, Yoshito, additional, Nakajima, Hideaki, additional, Suzuki, Hidenori, additional, Imajo, Yasuaki, additional, Yamada, Tomohiro, additional, Hasegawa, Tomohiko, additional, Kawaguchi, Kenichi, additional, Haruta, Yohei, additional, Terashima, Yoshinori, additional, Hirota, Ryosuke, additional, Tonomura, Hitoshi, additional, Sakata, Munehiro, additional, Iizuka, Yoichi, additional, Uei, Hiroshi, additional, Suzuki, Nobuyuki, additional, Akeda, Koji, additional, Tominaga, Hiroyuki, additional, Seki, Shoji, additional, Oshima, Yasushi, additional, Kaito, Takashi, additional, Otsuki, Bungo, additional, Nakanishi, Kazuo, additional, Kakutani, Kenichiro, additional, Funao, Haruki, additional, Yoshii, Toshitaka, additional, Sakai, Daisuke, additional, Ohba, Tetsuro, additional, Miyazaki, Masashi, additional, Terai, Hidetomi, additional, Inoue, Gen, additional, Okada, Seiji, additional, Imagama, Shiro, additional, and Kato, Satoshi, additional

Published
2024
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14. Is Intraoperative Blood Loss Volume in Elderly Cervical Spine Injury Surgery Greater in Patients with Ankylosis? A Multicenter Survey

Author

Uehara, Masashi, primary, Ikegami, Shota, additional, Takizawa, Takashi, additional, Oba, Hiroki, additional, Yokogawa, Noriaki, additional, Sasagawa, Takeshi, additional, Nakashima, Hiroaki, additional, Segi, Naoki, additional, Ito, Sadayuki, additional, Funayama, Toru, additional, Eto, Fumihiko, additional, Yamaji, Akihiro, additional, Watanabe, Kota, additional, Nori, Satoshi, additional, Takeda, Kazuki, additional, Furuya, Takeo, additional, Yunde, Atsushi, additional, Nakajima, Hideaki, additional, Yamada, Tomohiro, additional, Hasegawa, Tomohiko, additional, Terashima, Yoshinori, additional, Hirota, Ryosuke, additional, Suzuki, Hidenori, additional, Imajo, Yasuaki, additional, Tonomura, Hitoshi, additional, Sakata, Munehiro, additional, Hashimoto, Ko, additional, Onoda, Yoshito, additional, Kawaguchi, Kenichi, additional, Haruta, Yohei, additional, Suzuki, Nobuyuki, additional, Kato, Kenji, additional, Uei, Hiroshi, additional, Sawada, Hirokatsu, additional, Nakanishi, Kazuo, additional, Misaki, Kosuke, additional, Terai, Hidetomi, additional, Tamai, Koji, additional, Kuroda, Akiyoshi, additional, Inoue, Gen, additional, Kakutani, Kenichiro, additional, Kakiuchi, Yuji, additional, Kiyasu, Katsuhito, additional, Tominaga, Hiroyuki, additional, Tokumoto, Hiroto, additional, Iizuka, Yoichi, additional, Takasawa, Eiji, additional, Akeda, Koji, additional, Takegami, Norihiko, additional, Funao, Haruki, additional, Oshima, Yasushi, additional, Kaito, Takashi, additional, Sakai, Daisuke, additional, Yoshii, Toshitaka, additional, Ohba, Tetsuro, additional, Otsuki, Bungo, additional, Seki, Shoji, additional, Miyazaki, Masashi, additional, Ishihara, Masayuki, additional, Okada, Seiji, additional, Imagama, Shiro, additional, and Kato, Satoshi, additional

Published
2024
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15. A nationwide multicenter study of the cost effectiveness of five leading drugs for pharmacological management of cervicobrachial symptoms

Author

Wakao, Norimitsu, primary, Furuya, Takeo, additional, Yoshii, Toshitaka, additional, Arima, Hideyuki, additional, Yamato, Yu, additional, Nakashima, Hiroaki, additional, Imagama, Shiro, additional, Imajo, Yasuaki, additional, Miyamoto, Hiroshi, additional, Inoue, Gen, additional, Miyagi, Masayuki, additional, Kanbara, Shunsuke, additional, Iizuka, Yoichi, additional, Chikuda, Hirotaka, additional, Watanabe, Kei, additional, Kobayashi, Kazuyoshi, additional, Tsushima, Mikito, additional, Miyazaki, Masashi, additional, Yagi, Mitsuru, additional, Suzuki, Satoshi, additional, Takahata, Masahiko, additional, Hongo, Michio, additional, Koda, Masao, additional, Nagata, Keiji, additional, Mori, Kanji, additional, Suzuki, Akinobu, additional, Kaito, Takashi, additional, Murotani, Kenta, additional, Miyakoshi, Naohisa, additional, Hashizume, Hiroshi, additional, Matsuyama, Yukihiro, additional, Kawakami, Mamoru, additional, and Haro, Hirotaka, additional

Published
2023
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18. Epidemiology of Cervical Fracture/Cervical Spinal Cord Injury and Changes in Surgical Treatment Modalities in Elderly Individuals During a 10-year Period: A Nationwide Multicenter Study in Japan

Author

Segi, Naoki, Nakashima, Hiroaki, Machino, Masaaki, Ito, Sadayuki, Yokogawa, Noriaki, Sasagawa, Takeshi, Funayama, Toru, Eto, Fumihiko, Watanabe, Kota, Nori, Satoshi, Furuya, Takeo, Yunde, Atsushi, Nakajima, Hideaki, Hasegawa, Tomohiko, Yamada, Tomohiro, Terashima, Yoshinori, Hirota, Ryosuke, Suzuki, Hidenori, Imajo, Yasuaki, Ikegami, Shota, Uehara, Masashi, Tonomura, Hitoshi, Sakata, Munehiro, Hashimoto, Ko, Onoda, Yoshito, Kawaguchi, Kenichi, Haruta, Yohei, Suzuki, Nobuyuki, Kato, Kenji, Uei, Hiroshi, Sawada, Hirokatsu, Nakanishi, Kazuo, Misaki, Kosuke, Terai, Hidetomi, Tamai, Koji, Inoue, Gen, Shirasawa, Eiki, Kakutani, Kenichiro, Iizuka, Yoichi, Takasawa, Eiji, Akeda, Koji, Kiyasu, Katsuhito, Tominaga, Hiroyuki, Tokumoto, Hiroto, Funao, Haruki, Oshima, Yasushi, Yoshii, Toshitaka, Kaito, Takashi, Sakai, Daisuke, Ohba, Tetsuro, Seki, Shoji, Otsuki, Bungo, Ishihara, Masayuki, Miyazaki, Masashi, Okada, Seiji, Imagama, Shiro, and Kato, Satoshi

Abstract

Study Design Retrospective multicenter studyObjectives To investigate changes over a 10-years period in the profile of cervical spine and spinal cord injuries among the elderly in Japan.Methods The current multicenter study was a retrospective analysis of inpatients aged ≥65 years, suffering cervical fracture (CF) and/or cervical spinal cord injury (CSCI). We analyzed 1413 patients’ epidemiology (from 2010 to 2019). Moreover, 727 patients who underwent surgical treatment were analyzed in 2 groups: the early (2010-2014) and late period (2015-2019).Results Both the number of patients and number of surgical patients showed a significant increasing trend (P< .001), while the mean age, the distribution of injury levels and paralysis severity, and the proportion of surgical indications remained the same. The number of surgical patients doubled from 228 to 499 from the early to late periods. Posterior surgery was the most common approach (90.4%), instrumentation surgery with screws increased significantly, and the range of fusion was significantly longer in the late period (2.1 vs 2.7 levels, P= .001). Significantly worsening neurological symptoms were recorded in the late period (1.3% vs 5.8%, P= .006), with C5 palsy being the major one. Otherwise, perioperative, major, and other complications, including mortality, did not differ significantly in incidence.Conclusions Both the number of elderly CF and/or CSCI patients and number of patients undergoing surgery increased dramatically over the decade without any change in profile. Instrumentation surgeries with screws increased, without an increase in systemic complications.

Published
2024
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19. Effect of Intraoperative Tranexamic Acid on Perioperative Major Hemorrhage Requiring Transfusion in Patients Undergoing Elective Spine Surgery: A Propensity Score-Matched Analysis Using a National Inpatient Database.

Author

Honda, Akira, Iizuka, Yoichi, Michihata, Nobuaki, Uda, Kazuaki, Mieda, Tokue, Takasawa, Eiji, Ishiwata, Sho, Kakuta, Yohei, Tomomatsu, Yusuke, Ito, Shunsuke, Inomata, Kazuhiro, Matsui, Hiroki, Fushimi, Kiyohide, Yasunaga, Hideo, and Chikuda, Hirotaka

Subjects
SPINAL surgery, ELECTIVE surgery, BLOOD transfusion, TRANEXAMIC acid, DATABASES, ACUTE coronary syndrome
Abstract

Study Design: Retrospective cohort study. Objectives: This study aimed to examine whether the use of intravenous TXA in elective spine surgery is associated with reduced perioperative massive hemorrhage requiring transfusion. Methods: We extracted all patients who underwent decompression with or without fusion surgery for the cervical, thoracic, and lumbar spine between April 2012 and March 2019. The primary outcome was the occurrence of massive hemorrhage requiring transfusion, defined as at least 560 mL of blood transfusion within 2 days of spine surgery or the requirement of additional blood transfusion from 3-7 days postoperatively. Secondary outcomes were the occurrence of thrombotic complications (pulmonary embolism, acute coronary syndrome, and stroke) and postoperative hematoma requiring additional surgery. Results: We identified 83,821 eligible patients, with 9747 (12%) patients in the TXA group. Overall, massive hemorrhage requiring transfusion occurred in 781 (.9%) patients. Propensity score matching yielded 8394 pairs. In the matched cohort, the TXA group had a lower proportion of massive hemorrhage requiring transfusion than the control group (.7% vs 1.1%; P =.002). There was no significant difference in the occurrence of thrombotic complications and postoperative hematoma requiring additional surgery between both groups. The multivariable regression analysis also showed that the use of TXA was associated with significantly lower proportions of massive hemorrhage requiring transfusion (odds ratio,.62; 95% confidence interval,.43-.90; P =.012). Conclusions: In this analysis using real-world data, TXA use in elective spinal surgery was associated with reduced perioperative massive hemorrhage requiring transfusion without increasing thrombotic complications. Level of evidence: Prognostic Level Ⅲ [ABSTRACT FROM AUTHOR]

Published
2024
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20. Separation Surgery and Adjuvant Carbon Ion Radiotherapy for a Recurrent Solitary Fibrous Tumor/Hemangiopericytoma: A Case Report

Author

Tomomatsu, Yusuke, primary, Takasawa, Eiji, additional, Shiba, Shintaro, additional, Okamoto, Masahiko, additional, Ikota, Hayato, additional, Inomata, Kazuhiro, additional, Honda, Akira, additional, Ishiwata, Sho, additional, Mieda, Tokue, additional, Iizuka, Yoichi, additional, Ohno, Tatsuya, additional, and Chikuda, Hirotaka, additional

Published
2023
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23. Transoral Surgery for Irreducible Atlantoaxial Dislocation Complicated by Concomitant Aberrant Internal Carotid Arteries

Author

Inomata, Kazuhiro, primary, Takasawa, Eiji, additional, Matsubayashi, Yoshitaka, additional, Takayasu, Yukihiro, additional, Honda, Fumiaki, additional, Tobe, Masaru, additional, Ishiwata, Sho, additional, Kakuta, Yohei, additional, Tomomatsu, Yusuke, additional, Honda, Akira, additional, Ito, Shunsuke, additional, Mieda, Tokue, additional, Iizuka, Yoichi, additional, and Chikuda, Hirotaka, additional

Published
2023
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24. Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture

Author

Tamai, Koji, primary, Terai, Hidetomi, additional, Nakamura, Hiroaki, additional, Yokogawa, Noriaki, additional, Sasagawa, Takeshi, additional, Nakashima, Hiroaki, additional, Segi, Naoki, additional, Ito, Sadayuki, additional, Funayama, Toru, additional, Eto, Fumihiko, additional, Yamaji, Akihiro, additional, Watanabe, Kota, additional, Yamane, Junichi, additional, Takeda, Kazuki, additional, Furuya, Takeo, additional, Yunde, Atsushi, additional, Nakajima, Hideaki, additional, Yamada, Tomohiro, additional, Hasegawa, Tomohiko, additional, Terashima, Yoshinori, additional, Hirota, Ryosuke, additional, Suzuki, Hidenori, additional, Imajo, Yasuaki, additional, Ikegami, Shota, additional, Uehara, Masashi, additional, Tonomura, Hitoshi, additional, Sakata, Munehiro, additional, Hashimoto, Ko, additional, Onoda, Yoshito, additional, Kawaguchi, Kenichi, additional, Haruta, Yohei, additional, Suzuki, Nobuyuki, additional, Kato, Kenji, additional, Uei, Hiroshi, additional, Sawada, Hirokatsu, additional, Nakanishi, Kazuo, additional, Misaki, Kosuke, additional, Kuroda, Akiyoshi, additional, Inoue, Gen, additional, Kakutani, Kenichiro, additional, Kakiuchi, Yuji, additional, Kiyasu, Katsuhito, additional, Tominaga, Hiroyuki, additional, Tokumoto, Hiroto, additional, Iizuka, Yoichi, additional, Takasawa, Eiji, additional, Akeda, Koji, additional, Takegami, Norihiko, additional, Funao, Haruki, additional, Oshima, Yasushi, additional, Kaito, Takashi, additional, Sakai, Daisuke, additional, Yoshii, Toshitaka, additional, Ohba, Tetsuro, additional, Otsuki, Bungo, additional, Seki, Shoji, additional, Miyazaki, Masashi, additional, Ishihara, Masayuki, additional, Okada, Seiji, additional, Imagama, Shiro, additional, and Kato, Satoshi, additional

Published
2023
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25. Effects of Dementia on Outcomes after Cervical Spine Injuries in Elderly Patients: Evaluation of 1512 Cases in a Nationwide Multicenter Study in Japan

Author

Yamada, Yohei, primary, Yokogawa, Noriaki, additional, Kato, Satoshi, additional, Sasagawa, Takeshi, additional, Tsuchiya, Hiroyuki, additional, Nakashima, Hiroaki, additional, Segi, Naoki, additional, Ito, Sadayuki, additional, Funayama, Toru, additional, Eto, Fumihiko, additional, Yamaji, Akihiro, additional, Yamane, Junichi, additional, Nori, Satoshi, additional, Furuya, Takeo, additional, Yunde, Atsushi, additional, Nakajima, Hideaki, additional, Yamada, Tomohiro, additional, Hasegawa, Tomohiko, additional, Terashima, Yoshinori, additional, Hirota, Ryosuke, additional, Suzuki, Hidenori, additional, Imajo, Yasuaki, additional, Ikegami, Shota, additional, Uehara, Masashi, additional, Tonomura, Hitoshi, additional, Sakata, Munehiro, additional, Hashimoto, Ko, additional, Onoda, Yoshito, additional, Kawaguchi, Kenichi, additional, Haruta, Yohei, additional, Suzuki, Nobuyuki, additional, Kato, Kenji, additional, Uei, Hiroshi, additional, Sawada, Hirokatsu, additional, Nakanishi, Kazuo, additional, Misaki, Kosuke, additional, Terai, Hidetomi, additional, Tamai, Koji, additional, Kuroda, Akiyoshi, additional, Inoue, Gen, additional, Kakutani, Kenichiro, additional, Kakiuchi, Yuji, additional, Kiyasu, Katsuhito, additional, Tominaga, Hiroyuki, additional, Tokumoto, Hiroto, additional, Iizuka, Yoichi, additional, Takasawa, Eiji, additional, Akeda, Koji, additional, Takegami, Norihiko, additional, Funao, Haruki, additional, Oshima, Yasushi, additional, Kaito, Takashi, additional, Sakai, Daisuke, additional, Yoshii, Toshitaka, additional, Ohba, Tetsuro, additional, Otsuki, Bungo, additional, Seki, Shoji, additional, Miyazaki, Masashi, additional, Ishihara, Masayuki, additional, Okada, Seiji, additional, Imagama, Shiro, additional, and Watanabe, Kota, additional

Published
2023
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26. Prognostic Factors for Respiratory Dysfunction for Cervical Spinal Cord Injury and/or Cervical Fractures in Elderly Patients: A Multicenter Survey

Author

Hirota, Ryosuke, Terashima, Yoshinori, Ohnishi, Hirofumi, Yamashita, Toshihiko, Yokogawa, Noriaki, Sasagawa, Takeshi, Ando, Kei, Nakashima, Hiroaki, Segi, Naoki, Funayama, Toru, Eto, Fumihiko, Yamaji, Akihiro, Watanabe, Kota, Yamane, Junichi, Takeda, Kazuki, Furuya, Takeo, Yunde, Atsushi, Nakajima, Hideaki, Yamada, Tomohiro, Hasegawa, Tomohiko, Suzuki, Hidenori, Imajo, Yasuaki, Ikegami, Shota, Uehara, Masashi, Tonomura, Hitoshi, Sakata, Munehiro, Hashimoto, Ko, Onoda, Yoshito, Kawaguchi, Kenichi, Haruta, Yohei, Suzuki, Nobuyuki, Kato, Kenji, Uei, Hiroshi, Sawada, Hirokatsu, Nakanishi, Kazuo, Misaki, Kosuke, Terai, Hidetomi, Tamai, Koji, Shirasawa, Eiki, Inoue, Gen, Kakutani, Kenichiro, Kakiuchi, Yuji, Kiyasu, Katsuhito, Tominaga, Hiroyuki, Tokumoto, Hiroto, Iizuka, Yoichi, Takasawa, Eiji, Akeda, Koji, Takegami, Norihiko, Funao, Haruki, Oshima, Yasushi, Kaito, Takashi, Sakai, Daisuke, Yoshii, Toshitaka, Ohba, Tetsuro, Otsuki, Bungo, Seki, Shoji, Miyazaki, Masashi, Ishihara, Masayuki, Okada, Seiji, Imagama, Shiro, and Kato, Satoshi

Abstract

Study design Retrospective Cohort StudyObjective The purpose of this study was to investigate the prognosis of respiratory function in elderly patients with cervical spinal cord injury (SCI) and to identify predictive factors.Methods We included 1353 cases of elderly cervical SCI patients collected from 78 institutions in Japan. Patients who required early tracheostomy and ventilator management and those who developed respiratory complications were defined as the respiratory disability group. Patients’ background characteristics, injury mechanism, injury form, neurological disability, complications, and treatment methods were compared between the disability and non-disability groups. Multiple logistic regression analysis was used to examine the independent factors. Patients who required respiratory management for 6 months or longer after injury and those who died of respiratory complications were classified into the severe disability group and were compared with minor cases who were weaned off the respirator.Results A total of 104 patients (7.8%) had impaired respiratory function. Comparisons between the disabled and non-disabled groups and between the severe and mild injury groups yielded distinct trends. In multiple logistic regression analysis, age, blood glucose level, presence of ossification of posterior longitudinal ligament (OPLL), anterior vertebral hematoma, and critical paralysis were selected as independent risk factors.Conclusion Age, OPLL, severe paralysis, anterior vertebral hematoma, hypoalbuminemia, and blood glucose level at the time of injury were independent factors for respiratory failure. Hyperglycemia may have a negative effect on respiratory function in this condition.

Published
2024
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27. Association Between Early Surgery and Postoperative Opioid Use in Patients With Lumbar Disc Herniation: A Propensity Score-Matching Analysis Using an Administrative Claims Database in Japan

Author

Honda, Akira, primary, Iizuka, Yoichi, additional, Tokue, Mieda, additional, Takasawa, Eiji, additional, Ishiwata, Sho, additional, Tomomatsu, Yusuke, additional, Ito, Shunsuke, additional, Inomata, Kazuhiro, additional, Okada, Akira, additional, Matsui, Hiroki, additional, Yasunaga, Hideo, additional, and Chikuda, Hirotaka, additional

Published
2023
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28. Risk Factors for Early Mortality in Older Patients with Traumatic Cervical Spine Injuries—A Multicenter Retrospective Study of 1512 Cases

Author

Kobayashi, Motoya, primary, Yokogawa, Noriaki, additional, Kato, Satoshi, additional, Sasagawa, Takeshi, additional, Tsuchiya, Hiroyuki, additional, Nakashima, Hiroaki, additional, Segi, Naoki, additional, Ito, Sadayuki, additional, Funayama, Toru, additional, Eto, Fumihiko, additional, Yamaji, Akihiro, additional, Yamane, Junichi, additional, Nori, Satoshi, additional, Furuya, Takeo, additional, Yunde, Atsushi, additional, Nakajima, Hideaki, additional, Yamada, Tomohiro, additional, Hasegawa, Tomohiko, additional, Terashima, Yoshinori, additional, Hirota, Ryosuke, additional, Suzuki, Hidenori, additional, Imajo, Yasuaki, additional, Ikegami, Shota, additional, Uehara, Masashi, additional, Tonomura, Hitoshi, additional, Sakata, Munehiro, additional, Hashimoto, Ko, additional, Onoda, Yoshito, additional, Kawaguchi, Kenichi, additional, Haruta, Yohei, additional, Suzuki, Nobuyuki, additional, Kato, Kenji, additional, Uei, Hiroshi, additional, Sawada, Hirokatsu, additional, Nakanishi, Kazuo, additional, Misaki, Kosuke, additional, Terai, Hidetomi, additional, Tamai, Koji, additional, Kuroda, Akiyoshi, additional, Inoue, Gen, additional, Kakutani, Kenichiro, additional, Kakiuchi, Yuji, additional, Kiyasu, Katsuhito, additional, Tominaga, Hiroyuki, additional, Tokumoto, Hiroto, additional, Iizuka, Yoichi, additional, Takasawa, Eiji, additional, Akeda, Koji, additional, Takegami, Norihiko, additional, Funao, Haruki, additional, Oshima, Yasushi, additional, Kaito, Takashi, additional, Sakai, Daisuke, additional, Yoshii, Toshitaka, additional, Ohba, Tetsuro, additional, Otsuki, Bungo, additional, Seki, Shoji, additional, Miyazaki, Masashi, additional, Ishihara, Masayuki, additional, Okada, Seiji, additional, Imagama, Shiro, additional, and Watanabe, Kota, additional

Published
2023
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29. Epidemiology of Cervical Fracture/Cervical Spinal Cord Injury and Changes in Surgical Treatment Modalities in Elderly Individuals During a 10-year Period: A Nationwide Multicenter Study in Japan

Author

Segi, Naoki, primary, Nakashima, Hiroaki, additional, Machino, Masaaki, additional, Ito, Sadayuki, additional, Yokogawa, Noriaki, additional, Sasagawa, Takeshi, additional, Funayama, Toru, additional, Eto, Fumihiko, additional, Watanabe, Kota, additional, Nori, Satoshi, additional, Furuya, Takeo, additional, Yunde, Atsushi, additional, Nakajima, Hideaki, additional, Hasegawa, Tomohiko, additional, Yamada, Tomohiro, additional, Terashima, Yoshinori, additional, Hirota, Ryosuke, additional, Suzuki, Hidenori, additional, Imajo, Yasuaki, additional, Ikegami, Shota, additional, Uehara, Masashi, additional, Tonomura, Hitoshi, additional, Sakata, Munehiro, additional, Hashimoto, Ko, additional, Onoda, Yoshito, additional, Kawaguchi, Kenichi, additional, Haruta, Yohei, additional, Suzuki, Nobuyuki, additional, Kato, Kenji, additional, Uei, Hiroshi, additional, Sawada, Hirokatsu, additional, Nakanishi, Kazuo, additional, Misaki, Kosuke, additional, Terai, Hidetomi, additional, Tamai, Koji, additional, Inoue, Gen, additional, Shirasawa, Eiki, additional, Kakutani, Kenichiro, additional, Iizuka, Yoichi, additional, Takasawa, Eiji, additional, Akeda, Koji, additional, Kiyasu, Katsuhito, additional, Tominaga, Hiroyuki, additional, Tokumoto, Hiroto, additional, Funao, Haruki, additional, Oshima, Yasushi, additional, Yoshii, Toshitaka, additional, Kaito, Takashi, additional, Sakai, Daisuke, additional, Ohba, Tetsuro, additional, Seki, Shoji, additional, Otsuki, Bungo, additional, Ishihara, Masayuki, additional, Miyazaki, Masashi, additional, Okada, Seiji, additional, Imagama, Shiro, additional, and Kato, Satoshi, additional

Published
2023
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30. Influence of the timing of surgery for cervical spinal cord injury without bone injury in the elderly: A retrospective multicenter study

Author

Nori, Satoshi, primary, Watanabe, Kota, additional, Takeda, Kazuki, additional, Yamane, Junichi, additional, Kono, Hitoshi, additional, Yokogawa, Noriaki, additional, Sasagawa, Takeshi, additional, Ando, Kei, additional, Nakashima, Hiroaki, additional, Segi, Naoki, additional, Funayama, Toru, additional, Eto, Fumihiko, additional, Yamaji, Akihiro, additional, Furuya, Takeo, additional, Yunde, Atsushi, additional, Nakajima, Hideaki, additional, Yamada, Tomohiro, additional, Hasegawa, Tomohiko, additional, Terashima, Yoshinori, additional, Hirota, Ryosuke, additional, Suzuki, Hidenori, additional, Imajo, Yasuaki, additional, Ikegami, Shota, additional, Uehara, Masashi, additional, Tonomura, Hitoshi, additional, Sakata, Munehiro, additional, Hashimoto, Ko, additional, Onoda, Yoshito, additional, Kawaguchi, Kenichi, additional, Haruta, Yohei, additional, Uei, Hiroshi, additional, Sawada, Hirokatsu, additional, Nakanishi, Kazuo, additional, Misaki, Kosuke, additional, Terai, Hidetomi, additional, Tamai, Koji, additional, Shirasawa, Eiki, additional, Inoue, Gen, additional, Kiyasu, Katsuhito, additional, Iizuka, Yoichi, additional, Takasawa, Eiji, additional, Funao, Haruki, additional, Kaito, Takashi, additional, Yoshii, Toshitaka, additional, Ishihara, Masayuki, additional, Okada, Seiji, additional, Imagama, Shiro, additional, and Kato, Satoshi, additional

Published
2023
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33. Is Blood Loss Greater in Elderly Patients under Antiplatelet or Anticoagulant Medication for Cervical Spine Injury Surgery? A Japanese Multicenter Survey

Author

Uehara, Masashi, primary, Ikegami, Shota, additional, Takizawa, Takashi, additional, Oba, Hiroki, additional, Yokogawa, Noriaki, additional, Sasagawa, Takeshi, additional, Ando, Kei, additional, Nakashima, Hiroaki, additional, Segi, Naoki, additional, Funayama, Toru, additional, Eto, Fumihiko, additional, Yamaji, Akihiro, additional, Watanabe, Kota, additional, Nori, Satoshi, additional, Takeda, Kazuki, additional, Furuya, Takeo, additional, Orita, Sumihisa, additional, Nakajima, Hideaki, additional, Yamada, Tomohiro, additional, Hasegawa, Tomohiko, additional, Terashima, Yoshinori, additional, Hirota, Ryosuke, additional, Suzuki, Hidenori, additional, Imajo, Yasuaki, additional, Tonomura, Hitoshi, additional, Sakata, Munehiro, additional, Hashimoto, Ko, additional, Onoda, Yoshito, additional, Kawaguchi, Kenichi, additional, Haruta, Yohei, additional, Suzuki, Nobuyuki, additional, Kato, Kenji, additional, Uei, Hiroshi, additional, Sawada, Hirokatsu, additional, Nakanishi, Kazuo, additional, Misaki, Kosuke, additional, Terai, Hidetomi, additional, Tamai, Koji, additional, Shirasawa, Eiki, additional, Inoue, Gen, additional, Kakutani, Kenichiro, additional, Kakiuchi, Yuji, additional, Kiyasu, Katsuhito, additional, Tominaga, Hiroyuki, additional, Tokumoto, Hiroto, additional, Iizuka, Yoichi, additional, Takasawa, Eiji, additional, Akeda, Koji, additional, Takegami, Norihiko, additional, Funao, Haruki, additional, Oshima, Yasushi, additional, Kaito, Takashi, additional, Sakai, Daisuke, additional, Yoshii, Toshitaka, additional, Ohba, Tetsuro, additional, Otsuki, Bungo, additional, Seki, Shoji, additional, Miyazaki, Masashi, additional, Ishihara, Masayuki, additional, Okada, Seiji, additional, Aoki, Yasuchika, additional, Harimaya, Katsumi, additional, Murakami, Hideki, additional, Ishii, Ken, additional, Ohtori, Seiji, additional, Imagama, Shiro, additional, and Kato, Satoshi, additional

Published
2022
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34. Prognostic Factors for Respiratory Dysfunction for Cervical Spinal Cord Injury and/or Cervical Fractures in Elderly Patients: A Multicenter Survey

Author

Hirota, Ryosuke, primary, Terashima, Yoshinori, additional, Ohnishi, Hirofumi, additional, Yamashita, Toshihiko, additional, Yokogawa, Noriaki, additional, Sasagawa, Takeshi, additional, Ando, Kei, additional, Nakashima, Hiroaki, additional, Segi, Naoki, additional, Funayama, Toru, additional, Eto, Fumihiko, additional, Yamaji, Akihiro, additional, Watanabe, Kota, additional, Yamane, Junichi, additional, Takeda, Kazuki, additional, Furuya, Takeo, additional, Yunde, Atsushi, additional, Nakajima, Hideaki, additional, Yamada, Tomohiro, additional, Hasegawa, Tomohiko, additional, Suzuki, Hidenori, additional, Imajo, Yasuaki, additional, Ikegami, Shota, additional, Uehara, Masashi, additional, Tonomura, Hitoshi, additional, Sakata, Munehiro, additional, Hashimoto, Ko, additional, Onoda, Yoshito, additional, Kawaguchi, Kenichi, additional, Haruta, Yohei, additional, Suzuki, Nobuyuki, additional, Kato, Kenji, additional, Uei, Hiroshi, additional, Sawada, Hirokatsu, additional, Nakanishi, Kazuo, additional, Misaki, Kosuke, additional, Terai, Hidetomi, additional, Tamai, Koji, additional, Shirasawa, Eiki, additional, Inoue, Gen, additional, Kakutani, Kenichiro, additional, Kakiuchi, Yuji, additional, Kiyasu, Katsuhito, additional, Tominaga, Hiroyuki, additional, Tokumoto, Hiroto, additional, Iizuka, Yoichi, additional, Takasawa, Eiji, additional, Akeda, Koji, additional, Takegami, Norihiko, additional, Funao, Haruki, additional, Oshima, Yasushi, additional, Kaito, Takashi, additional, Sakai, Daisuke, additional, Yoshii, Toshitaka, additional, Ohba, Tetsuro, additional, Otsuki, Bungo, additional, Seki, Shoji, additional, Miyazaki, Masashi, additional, Ishihara, Masayuki, additional, Okada, Seiji, additional, Imagama, Shiro, additional, and Kato, Satoshi, additional

Published
2022
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36. Risk factors for severe lower extremity ischemia following venoarterial extracorporeal membrane oxygenation: an analysis using a nationwide inpatient database

Author

Honda, Akira, primary, Michihata, Nobuaki, additional, Iizuka, Yoichi, additional, Uda, Kazuaki, additional, Morita, Kojiro, additional, Mieda, Tokue, additional, Takasawa, Eiji, additional, Ishiwata, Sho, additional, Tajika, Tsuyoshi, additional, Matsui, Hiroki, additional, Fushimi, Kiyohide, additional, Yasunaga, Hideo, additional, and Chikuda, Hirotaka, additional

Published
2022
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37. Effect of Early vs Delayed Surgical Treatment on Motor Recovery in Incomplete Cervical Spinal Cord Injury With Preexisting Cervical Stenosis

Author

Chikuda, Hirotaka, Koyama, Yurie, Matsubayashi, Yoshitaka, Ogata, Toru, Ohtsu, Hiroshi, Sugita, Shurei, Sumitani, Masahiko, Kadono, Yuho, Miura, Toshiki, Tanaka, Sakae, Akiyama, Toru, Ando, Kei, Anno, Masato, Azuma, Seiichi, Endo, Kenji, Endo, Toru, Fujiyoshi, Takayuki, Furuya, Takeo, Hayashi, Hiroyuki, Higashikawa, Akiro, Hiyama, Akihiko, Horii, Chiaki, Iimoto, Seiji, Iizuka, Yoichi, Ikuma, Hisanori, Imagama, Shiro, Inokuchi, Koichi, Inoue, Hirokazu, Inoue, Tomoo, Ishii, Keisuke, Ishii, Masayoshi, Ito, Takui, Itoi, Akira, Iwamoto, Kohei, Iwasaki, Motoki, Kaito, Takashi, Kato, Tsuyoshi, Katoh, Hiroyuki, Kawaguchi, Yoshiharu, Kawano, Osamu, Kimura, Atsushi, Kobayashi, Kazuyoshi, Koda, Masao, Komatsu, Miki, Kumagai, Gentaro, Maeda, Takeshi, Makino, Takahiro, Mannoji, Chikato, Masuda, Kazuhiro, Masuda, Keisuke, Matsumoto, Koji, Matsumoto, Morio, Matsunaga, Shunji, Matsuyama, Yukihiro, Mieda, Tokue, Miyoshi, Kota, Mochida, Joji, Moridaira, Hiroshi, Motegi, Hiroyuki, Nakagawa, Yukihiro, Nohara, Yutaka, Oae, Kazunori, Ogawa, Shinji, Okazaki, Rentaro, Okuda, Akinori, Onishi, Eijiro, Ono, Atsushi, Oshima, Masashi, Oshita, Yusuke, Saita, Kazuo, Sasao, Yutaka, Sato, Kimiaki, Sawakami, Kimihiko, Seichi, Atsushi, Seki, Shoji, Shigematsu, Hideki, Suda, Kota, Takagi, Yasutaka, Takahashi, Masahito, Takahashi, Ryosuke, Takasawa, Eiji, Takenaka, Shota, Takeshita, Katsushi, Takeshita, Yujiro, Tokioka, Takamitsu, Tokuhashi, Yasuaki, Tonosu, Juichi, Uei, Hiroshi, Wada, Kanichiro, Watanabe, Masahiko, Yahata, Tadashi, Yamada, Kei, Yasuda, Taketoshi, Yasui, Keigo, and Yoshii, Toshitaka

Subjects
Online Only, Neurology, Research, Original Investigation
Abstract

Key Points Question Does early surgical treatment yield better motor recovery than delayed surgical treatment for patients with preexisting cervical canal stenosis sustaining acute traumatic spinal cord injury? Findings In this randomized clinical trial that included 72 patients with motor-incomplete cervical spinal cord injury, there was no statistically significant difference between groups in mean improvement in American Spinal Injury Association motor score, total score in the spinal cord independence measure, or patients’ ability to walk at 1 year. Early surgical treatment was associated with higher motor scores than delayed surgical treatment in the first 6 months. Meaning These findings suggest that among patients with motor-incomplete cervical spinal cord injury, early surgical treatment did not significantly improve motor recovery at 1 year compared with delayed surgical treatment but showed accelerated recovery., This randomized clinical trial assesses motor recovery outcomes in early vs delayed surgical treatment for patients with acute traumatic incomplete cervical spinal cord injury associated with preexisting canal stenosis., Importance The optimal management for acute traumatic cervical spinal cord injury (SCI) is unknown. Objective To determine whether early surgical decompression results in better motor recovery than delayed surgical treatment in patients with acute traumatic incomplete cervical SCI associated with preexisting canal stenosis but without bone injury. Design, Setting, and Participants This multicenter randomized clinical trial was conducted in 43 tertiary referral centers in Japan from December 2011 through November 2019. Patients aged 20 to 79 years with motor-incomplete cervical SCI with preexisting canal stenosis (American Spinal Injury Association [ASIA] Impairment Scale C; without fracture or dislocation) were included. Data were analyzed from September to November 2020. Interventions Patients were randomized to undergo surgical treatment within 24 hours after admission or delayed surgical treatment after at least 2 weeks of conservative treatment. Main Outcomes and Measures The primary end points were improvement in the mean ASIA motor score, total score of the spinal cord independence measure, and the proportion of patients able to walk independently at 1 year after injury. Results Among 72 randomized patients, 70 patients (mean [SD] age, 65.1 [9.4] years; age range, 41-79 years; 5 [7%] women and 65 [93%] men) were included in the full analysis population (37 patients assigned to early surgical treatment and 33 patients assigned to delayed surgical treatment). Of these, 56 patients (80%) had data available for at least 1 primary outcome at 1 year. There was no significant difference among primary end points for the early surgical treatment group compared with the delayed surgical treatment group (mean [SD] change in ASIA motor score, 53.7 [14.7] vs 48.5 [19.1]; difference, 5.2; 95% CI, −4.2 to 14.5; P = .27; mean [SD] SCIM total score, 77.9 [22.7] vs 71.3 [27.3]; P = .34; able to walk independently, 21 of 30 patients [70.0%] vs 16 of 26 patients [61.5%]; P = .51). A mixed-design analysis of variance revealed a significant difference in the mean change in ASIA motor scores between the groups (F1,49 = 4.80; P = .03). The early surgical treatment group, compared with the delayed surgical treatment group, had greater motor scores than the delayed surgical treatment group at 2 weeks (mean [SD] score, 34.2 [18.8] vs 18.9 [20.9]), 3 months (mean [SD] score, 49.1 [15.1] vs 37.2 [20.9]), and 6 months (mean [SD] score, 51.5 [13.9] vs 41.3 [23.4]) after injury. Adverse events were common in both groups (eg, worsening of paralysis, 6 patients vs 6 patients; death, 3 patients vs 3 patients). Conclusions and Relevance These findings suggest that among patients with cervical SCI, early surgical treatment produced similar motor regain at 1 year after injury as delayed surgical treatment but showed accelerated recovery within the first 6 months. These exploratory results suggest that early surgical treatment leads to faster neurological recovery, which requires further validation. Trial Registration ClinicalTrials.gov Identifier: NCT01485458; umin.ac.jp/ctr Identifier: UMIN000006780

Published
2021

43. Risk Factors for Throwing-Related Shoulder and Elbow Pain in Adolescent Baseball Players: A Prospective Study of Physical and Developmental Factors

Author

Tajika, Tsuyoshi, primary, Oya, Noboru, additional, Kuboi, Takuro, additional, Endo, Fumitaka, additional, Ichinose, Tsuyoshi, additional, Shimoyama, Daisuke, additional, Sasaki, Tsuyoshi, additional, Hamano, Noritaka, additional, Omodaka, Takuya, additional, Kobayashi, Hiroki, additional, Mieda, Tokue, additional, Okamura, Koichi, additional, Shitara, Hitoshi, additional, Iizuka, Yoichi, additional, Yamamoto, Atsushi, additional, Nakajima, Ichiro, additional, Kobayashi, Tsutomu, additional, Sakamoto, Masaaki, additional, Takagishi, Kenji, additional, and Chikuda, Hirotaka, additional

Published
2021
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44. The Association Between the Rotator Cuff Status and the Severity and Recovery of Weakness in the Shoulder Abductor Strength in a Case of Proximal Type Cervical Spondylotic Amyotrophy.

Author

Ishiwata, Sho, Iizuka, Yoichi, Shitara, Hitoshi, Mieda, Tokue, Takasawa, Eiji, Tsunoda, Daisuke, Kakuta, Yohei, Honda, Akira, Ito, Shunsuke, Inomata, Kazuhiro, Sasaki, Tsuyoshi, Hamano, Noritaka, Tajika, Tsuyoshi, and Chikuda, Hirotaka

Abstract

Study Design: Case series study. Objective: We aimed to clarify the prevalence of rotator cuff tear (RCT), and the association between RCT and the severity and prognosis in patients with proximal type cervical spondylotic amyotrophy (CSA). Methods: We retrospectively analyzed 35 proximal type CSA patients who were treated conservatively. The following data was collected: age, rotator cuff status on MRI, manual muscle test (MMT) score of shoulder abductor and biceps brachii muscles both at the first visit and final follow-up. We investigated the prevalence of RCT and the association between the rotator cuff status, and the severity and recovery of upper extremity weakness in patients with proximal type CSA. Results: Of the 35 patients, 21 had an RCT on MRI, indicating that the prevalence of RCT in patients with proximal type CSA was 60%. An age-adjusted analysis showed that the presence of RCT was significantly associated with the MMT score of the shoulder abductor muscles both at the first visit and at the final follow-up. The presence of RCT was significantly associated with the recovery of the shoulder abductor muscles. The size of the RCT was negatively correlated with the MMT score of the shoulder abductor muscles at the final follow-up. The size of the RCT was independently correlated with the change of the MMT score of the shoulder abductor muscles. Conclusion: RCT was detected in >50% in patients with proximal type CSA, and the presence and severity of RCT can be used as prognostic factors for proximal type CSA patients who are treated conservatively. [ABSTRACT FROM AUTHOR]

Published
2022
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49. Angiomatous Meningioma in the Craniocervical Junction

Author

Ito, Shunsuke, Iizuka, Yoichi, Aihara, Masanori, Koshi, Hiromi, Mieda, Tokue, Takasawa, Eiji, Ishiwata, Sho, Tomomatsu, Yusuke, Honda, Akira, Inomata, Kazuhiro, and Chikuda, Hirotaka

Subjects
Article Subject
Abstract

Introduction. Spinal angiomatous meningioma arising in the craniocervical junction has not been reported. Case Presentation. A 68-year-old man presented to our hospital with pain in the back and left leg. He showed slight motor weakness in his upper extremities. Magnetic resonance imaging revealed a mass with marked enhancement in the craniocervical junction. Computed tomography angiography showed feeding vessels arising from the right vertebral artery. Preoperative embolization of the feeding vessels was performed to reduce intraoperative bleeding. Gross total resection of the tumor was achieved by debulking and piecemeal resection. The tumor attachment to the dura mater was also resected (Simpson grade 1 resection). A histopathological examination confirmed the diagnosis of an angiomatous meningioma. The patient’s symptoms improved shortly after surgery. Conclusions. We achieved gross total resection of spinal angiomatous meningioma arising in the craniocervical junction. A preoperative evaluation and embolization of the feeding arteries may help prevent massive intraoperative bleeding.

Published
2021
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