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1. A Pilot Single-Site Randomized Control Trial: Investigating the Use of Donor Milk in the Late Preterm and Term Infant in the Neonatal Intensive Care Unit

Author

Neema Pithia, Tristan Grogan, Meena Garg, Kalpashri Kesavan, and Kara Calkins

Abstract

Objective: We aimed to study the use of donor milk (DM) in term and late preterm infants (LPIs) when mother’s own milk (MOM) was unavailable. We hypothesized this study would be feasible and breastfeeding attempts and the percentage of MOM (MOM%) would increase with DM without adversely affecting growth. Study Design: This was a pilot study (n=32). Infants with gestational age >34 weeks admitted to the neonatal intensive care unit were included. Infants were randomized to: the human milk (MOM+DM) or formula (MOM+F) groups. Result: Consent rate was 52%. Breastfeeding attempts increased significantly over time in the MOM+DM group compared to the MOM+F group (group p=0.41, time p =0.02, group*time p=0.01). Growth at multiple time points was similar when the two groups were compared. Conclusion: A study randomizing term infants and LPIs to DM or formula when MOM is unavailable is feasible. DM may increase breastfeeding attempts without compromising growth.

Published
2023
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2. Growth Failure Prevalence in Neonates with Gastroschisis : A Statewide Cohort Study

Author

Katie M. Strobel, Tahmineh Romero, Katelin Kramer, Erika Fernandez, Catherine Rottkamp, Cherry Uy, Roberta Keller, Laurel Moyer, Francis Poulain, Jae H. Kim, Daniel A. DeUgarte, Kara L. Calkins, Nina Boe, Erin Brown, Diana Farmer, Nancy Field, Herman Hedriana, Shinjiro Hirose, Gina James, Elyse Love, Amelia McLennan, Amy Powne, Laila Rhee Morris, Payam Saadai, Sherzana Sunderji, Veronique Tache, Jay Yeh, M. Baraa Allaf, Katie Bacca, Lisa Carroll, Brian Crosland, Robert Day, Jennifer Duffy, David Gibbs, Afshan Hameed, Tamara Hatfield, Alexandra Iacob, Jennifer Jolley, Mustafa Kabeer, Nafiz Kiciman, Nancy Lee, Carol Major, Joshua Makhoul, Yona Nicolau, Manuel Porto, Rebecca Post, Pamela Rumney, Lizette Spiers, Peter Yu, Irfan Ahmad, Nita Doshi, Yigit Guner, Wyman Lai, Pierangelo Renella, Yalda Afshar, Kara Calkins, Ilina Pluym, Daniel DeUgarte, Uday Devaskar, Jaime Deville, Viviana Fajardo, Meena Garg, Christina Han, Kerry Holliman, Carla Janzen, Howard Jen, Suhas Kallapur, Steven Lee, Steven Lerman, Aisling Murphy, Tina Nguyen, Rashmi Rao, Animesh Sabnis, Gary Satou, Mark Sklansky, Katie Strobel, Renea Sturm, Khalil Tabsh, Thalia Wong, Rebecca Adami, Tracy Anton, Jerasimos Ballas, Stephen Bickler, Andrew Hull, Marni Jacobs, Diana Johnson, Karen Kling, Leah Lamale-Smith, Sarah Lazar, Louise Laurent, Tzu-Ning Liu, Celestine Magallanes, Dora Melber, Mana Parast, Mishella Perez, Dolores Pretorius, Sandy Ramos, Maryam Tarsa, Douglas Woelkers, Kathy Zhang-Rutledge, Ian Fraser Golding, Heather Sun, Katie Archbold, Lisa Arcilla, Stacie Bennet, Paul Brakeman, Melissa Catenacci, Shilpa Chetty, Hillary Copp, Erin Corbett, Valerie Dougherty, Sarah Downum, Vickie Feldstein, Neda Ghaffari, Ruth Goldstein, Juan Gonzalez-Velez, Veronica Gonzalez, Kristen Gosnell, Joanne Gras, Michael Harrison, Whitnee Hogan, Romobia Hutchinson, Roxanna Irani, Priyanka Jha, Erna Josiah-Davis, Hanmin Lee, Billie Lianoglou, Jennifer Lucero, Leslie Lusk, Tippi MacKenzie, Anne Mardy, Erin Matsuda, Anita Moon-Grady, Tara Morgan, Amy Murtha, Mary Norton, Natalie Oman, Benjamin Padilla, Sachi Patel, Shabnam Peyandi, Andrew Phelps, Liina Poder, Annalisa Post, Larry Rand, Diana Robles, Frederico Rocha, Howard Rosenfeld, Melissa Rosenstein, Janice Scudmore, Dorothy Shum, Nasim Sobhani, Teresa Sparks, Katherine Swanson, Martha Tesfalul, Stephanie Valderramos, Lan Vu, and Amanda Yeaton-Massey

Subjects
Male, Pediatrics, medicine.medical_specialty, Standard score, Linear Growth Failure, California, Article, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, 030225 pediatrics, Prevalence, medicine, Hospital discharge, Humans, 030212 general & internal medicine, Growth Disorders, Retrospective Studies, Gastroschisis, Fetus, business.industry, Body Weight, Infant, Newborn, Gestational age, medicine.disease, Body Height, Multicenter study, Pediatrics, Perinatology and Child Health, Female, business, Cohort study
Abstract

OBJECTIVES: To perform a multicenter study to assess growth failure in hospitalized infants with gastroschisis. STUDY DESIGN: This study included neonates with gastroschisis within sites in the University of California Fetal Consortium (UCFC). The study’s primary outcome was growth failure at hospital discharge, defined as a weight or length z-score decrease > 0.8 from birth. Regression analysis was performed to assess changes in z-scores over time. RESULTS: Among 125 infants with gastroschisis, the median gestational age was 37 weeks (IQR 35–37). Length of stay was 32 days (23–60); 55% developed weight or length growth failure at discharge (28% had weight growth failure, 42% had length growth failure, and 15% had both weight and length growth failure). Weight and length z-scores at 14 d, 30 d, and discharge were less than birth (p

Published
2021
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