Search

Your search keyword '"Keller, Matthew W."' showing total 19 results
Start Over Author "Keller, Matthew W." Search Limiters Full Text
19 results on '"Keller, Matthew W."'

1. Antigenic Characterization of Circulating and Emerging SARS-CoV-2 Variants in the U.S. throughout the Delta to Omicron Waves

Author

Di, Han, primary, Pusch, Elizabeth A., additional, Jones, Joyce, additional, Kovacs, Nicholas A., additional, Hassell, Norman, additional, Sheth, Mili, additional, Lynn, Kelly Sabrina, additional, Keller, Matthew W., additional, Wilson, Malania M., additional, Keong, Lisa M., additional, Cui, Dan, additional, Park, So Hee, additional, Chau, Reina, additional, Lacek, Kristine A., additional, Liddell, Jimma D., additional, Kirby, Marie K., additional, Yang, Genyan, additional, Johnson, Monique, additional, Thor, Sharmi, additional, Zanders, Natosha, additional, Feng, Chenchen, additional, Surie, Diya, additional, DeCuir, Jennifer, additional, Lester, Sandra N., additional, Atherton, Lydia, additional, Hicks, Heather, additional, Tamin, Azaibi, additional, Harcourt, Jennifer L., additional, Coughlin, Melissa M., additional, Self, Wesley H., additional, Rhoads, Jillian P., additional, Gibbs, Kevin W., additional, Hager, David N., additional, Shapiro, Nathan I., additional, Exline, Matthew C., additional, Lauring, Adam S., additional, Rambo-Martin, Benjamin, additional, Paden, Clinton R., additional, Kondor, Rebecca J., additional, Lee, Justin S., additional, Barnes, John R., additional, Thornburg, Natalie J., additional, Zhou, Bin, additional, Wentworth, David E., additional, and Davis, Charles Todd, additional

Published
2024
Full Text
View/download PDF

2. Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants

Author

Welch, Nicole L., Zhu, Meilin, Hua, Catherine, Weller, Juliane, Mirhashemi, Marzieh Ezzaty, Nguyen, Tien G., Mantena, Sreekar, Bauer, Matthew R., Shaw, Bennett M., Ackerman, Cheri M., Thakku, Sri Gowtham, Tse, Megan W., Kehe, Jared, Uwera, Marie-Martine, Eversley, Jacqueline S., Bielwaski, Derek A., McGrath, Graham, Braidt, Joseph, Johnson, Jeremy, Cerrato, Felecia, Moreno, Gage K., Krasilnikova, Lydia A., Petros, Brittany A., Gionet, Gabrielle L., King, Ewa, Huard, Richard C., Jalbert, Samantha K., Cleary, Michael L., Fitzgerald, Nicholas A., Gabriel, Stacey B., Gallagher, Glen R., Smole, Sandra C., Madoff, Lawrence C., Brown, Catherine M., Keller, Matthew W., Wilson, Malania M., Kirby, Marie K., Barnes, John R., Park, Daniel J., Siddle, Katherine J., Happi, Christian T., Hung, Deborah T., Springer, Michael, MacInnis, Bronwyn L., Lemieux, Jacob E., Rosenberg, Eric, Branda, John A., Blainey, Paul C., Sabeti, Pardis C., and Myhrvold, Cameron

Published
2022
Full Text
View/download PDF

3. Multiplex Real-Time Reverse Transcription PCR for Influenza A Virus, Influenza B Virus, and Severe Acute Respiratory Syndrome Coronavirus 2

Author

Shu, Bo, Kirby, Marie K., Davis, William G., Warnes, Christine, Liddell, Jimma, Liu, Ji, Wu, Kai-Hui, Hassell, Norman, Benitez, Alvaro J., Wilson, Malania M., Keller, Matthew W., Rambo-Martin, Benjamin L., Camara, Yamundow, Winter, Jorn, Kondor, Rebecca J., Zhou, Bin, Spies, Stacey, Rose, Laura E., Winchell, Jonas M., Limbago, Brandi M., Wentworth, David E., and Barnes, John R.

Subjects
Influenza -- Diagnosis, Molecular diagnostic techniques -- Usage, Polymerase chain reaction -- Usage, Health
Abstract

An outbreak of pneumonia of unknown etiology in Wuhan, China, was reported to the World Health Organization on December 31, 2019 (1). Researchers determined that the illness, later known as [...]

Published
2021
Full Text
View/download PDF

4. SARS-CoV-2 spike D614G change enhances replication and transmission

Author

Zhou, Bin, Thao, Tran Thi Nhu, Hoffmann, Donata, Taddeo, Adriano, Ebert, Nadine, Labroussaa, Fabien, Pohlmann, Anne, King, Jacqueline, Steiner, Silvio, Kelly, Jenna N., Portmann, Jasmine, Halwe, Nico Joel, Ulrich, Lorenz, Trüeb, Bettina Salome, Fan, Xiaoyu, Hoffmann, Bernd, Wang, Li, Thomann, Lisa, Lin, Xudong, Stalder, Hanspeter, Pozzi, Berta, de Brot, Simone, Jiang, Nannan, Cui, Dan, Hossain, Jaber, Wilson, Malania M., Keller, Matthew W., Stark, Thomas J., Barnes, John R., Dijkman, Ronald, Jores, Joerg, Benarafa, Charaf, Wentworth, David E., Thiel, Volker, and Beer, Martin

Published
2021
Full Text
View/download PDF

5. In‐field detection and characterization of B/Victoria lineage deletion variant viruses causing early influenza activity and an outbreak in Louisiana, 2019

Author

Shu, Bo, primary, Wilson, Malania M., additional, Keller, Matthew W., additional, Tran, Ha, additional, Sokol, Theresa, additional, Lee, Grace, additional, Rambo‐Martin, Benjamin L., additional, Kirby, Marie K., additional, Hassell, Norman, additional, Haydel, Danielle, additional, Hand, Julie, additional, Wentworth, David E., additional, and Barnes, John R., additional

Published
2024
Full Text
View/download PDF

6. Targeted amplification and genetic sequencing of the severe acute respiratory syndrome coronavirus 2 surface glycoprotein

Author

Keller, Matthew W., primary, Keong, Lisa M., additional, Rambo-Martin, Benjamin L., additional, Hassell, Norman, additional, Lacek, Kristine A., additional, Wilson, Malania M., additional, Kirby, Marie K., additional, Liddell, Jimma, additional, Owuor, D. Collins, additional, Sheth, Mili, additional, Madden, Joseph, additional, Lee, Justin S., additional, Kondor, Rebecca J., additional, Wentworth, David E., additional, and Barnes, John R., additional

Published
2023
Full Text
View/download PDF

7. Author Correction: Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants

Author

Welch, Nicole L., primary, Zhu, Meilin, additional, Hua, Catherine, additional, Weller, Juliane, additional, Mirhashemi, Marzieh Ezzaty, additional, Nguyen, Tien G., additional, Mantena, Sreekar, additional, Bauer, Matthew R., additional, Shaw, Bennett M., additional, Ackerman, Cheri M., additional, Thakku, Sri Gowtham, additional, Tse, Megan W., additional, Kehe, Jared, additional, Uwera, Marie-Martine, additional, Eversley, Jacqueline S., additional, Bielwaski, Derek A., additional, McGrath, Graham, additional, Braidt, Joseph, additional, Johnson, Jeremy, additional, Cerrato, Felecia, additional, Moreno, Gage K., additional, Krasilnikova, Lydia A., additional, Petros, Brittany A., additional, Gionet, Gabrielle L., additional, King, Ewa, additional, Huard, Richard C., additional, Jalbert, Samantha K., additional, Cleary, Michael L., additional, Fitzgerald, Nicholas A., additional, Gabriel, Stacey B., additional, Gallagher, Glen R., additional, Smole, Sandra C., additional, Madoff, Lawrence C., additional, Brown, Catherine M., additional, Keller, Matthew W., additional, Wilson, Malania M., additional, Kirby, Marie K., additional, Barnes, John R., additional, Park, Daniel J., additional, Siddle, Katherine J., additional, Happi, Christian T., additional, Hung, Deborah T., additional, Springer, Michael, additional, MacInnis, Bronwyn L., additional, Lemieux, Jacob E., additional, Rosenberg, Eric, additional, Branda, John A., additional, Blainey, Paul C., additional, Sabeti, Pardis C., additional, and Myhrvold, Cameron, additional

Published
2023
Full Text
View/download PDF

8. Manipulating Fermentation Pathways in the Hyperthermophilic Archaeon Pyrococcus furiosus for Ethanol Production up to 95°C Driven by Carbon Monoxide Oxidation

Author

Lipscomb, Gina L., primary, Crowley, Alexander T., additional, Nguyen, Diep M. N., additional, Keller, Matthew W., additional, O’Quinn, Hailey C., additional, Tanwee, Tania N. N., additional, Vailionis, Jason L., additional, Zhang, Ke, additional, Zhang, Ying, additional, Kelly, Robert M., additional, and Adams, Michael W. W., additional

Published
2023
Full Text
View/download PDF

12. Influenza A Virus Field Surveillance at a Swine-Human Interface

Author

Rambo-Martin, Benjamin L., primary, Keller, Matthew W., additional, Wilson, Malania M., additional, Nolting, Jacqueline M., additional, Anderson, Tavis K., additional, Vincent, Amy L., additional, Bagal, Ujwal R., additional, Jang, Yunho, additional, Neuhaus, Elizabeth B., additional, Davis, C. Todd, additional, Bowman, Andrew S., additional, Wentworth, David E., additional, and Barnes, John R., additional

Published
2020
Full Text
View/download PDF

13. Multiplex Real-Time Reverse Transcription PCR for Influenza A Virus, Influenza B Virus, and Severe Acute Respiratory Syndrome Coronavirus 2.

Author

Bo Shu, Kirby, Marie K., Davis, William G., Warnes, Christine, Liddell, Jimma, Ji Liu, Kai-Hui Wu, Hassell, Norman, Benitez, Alvaro J., Wilson, Malania M., Keller, Matthew W., Rambo-Martin, Benjamin L., Camara, Yamundow, Winter, Jörn, Kondor, Rebecca J., Bin Zhou, Spies, Stacey, Rose, Laura E., Winchell, Jonas M., and Limbago, Brandi M.

Subjects
INFLUENZA B virus, INFLUENZA viruses, INFLUENZA A virus, COVID-19, INFLUENZA, COVID-19 pandemic
Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in late 2019, and the outbreak rapidly evolved into the current coronavirus disease pandemic. SARS-CoV-2 is a respiratory virus that causes symptoms similar to those caused by influenza A and B viruses. On July 2, 2020, the US Food and Drug Administration granted emergency use authorization for in vitro diagnostic use of the Influenza SARS-CoV-2 Multiplex Assay. This assay detects influenza A virus at 102.0, influenza B virus at 102.2, and SARS-CoV-2 at 100.3 50% tissue culture or egg infectious dose, or as few as 5 RNA copies/reaction. The simultaneous detection and differentiation of these 3 major pathogens increases overall testing capacity, conserves resources, identifies co-infections, and enables efficient surveillance of influenza viruses and SARS-CoV-2. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

15. Author Correction: Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants

Author

Welch, Nicole L., Zhu, Meilin, Hua, Catherine, Weller, Juliane, Mirhashemi, Marzieh Ezzaty, Nguyen, Tien G., Mantena, Sreekar, Bauer, Matthew R., Shaw, Bennett M., Ackerman, Cheri M., Thakku, Sri Gowtham, Tse, Megan W., Kehe, Jared, Uwera, Marie-Martine, Eversley, Jacqueline S., Bielwaski, Derek A., McGrath, Graham, Braidt, Joseph, Johnson, Jeremy, Cerrato, Felecia, Moreno, Gage K., Krasilnikova, Lydia A., Petros, Brittany A., Gionet, Gabrielle L., King, Ewa, Huard, Richard C., Jalbert, Samantha K., Cleary, Michael L., Fitzgerald, Nicholas A., Gabriel, Stacey B., Gallagher, Glen R., Smole, Sandra C., Madoff, Lawrence C., Brown, Catherine M., Keller, Matthew W., Wilson, Malania M., Kirby, Marie K., Barnes, John R., Park, Daniel J., Siddle, Katherine J., Happi, Christian T., Hung, Deborah T., Springer, Michael, MacInnis, Bronwyn L., Lemieux, Jacob E., Rosenberg, Eric, Branda, John A., Blainey, Paul C., Sabeti, Pardis C., and Myhrvold, Cameron

Published
2024
Full Text
View/download PDF

17. Discriminating North American Swine Influenza Viruses with a Portable, One-Step, Triplex Real-Time RT-PCR Assay, and Portable Sequencing.

Author

Kirby MK, Shu B, Keller MW, Wilson MM, Rambo-Martin BL, Jang Y, Liddell J, Salinas Duron E, Nolting JM, Bowman AS, Davis CT, Wentworth DE, and Barnes JR

Subjects
Animals, Swine, North America, Real-Time Polymerase Chain Reaction methods, Reverse Transcriptase Polymerase Chain Reaction methods, Hemagglutinin Glycoproteins, Influenza Virus genetics, RNA, Viral genetics, Multiplex Polymerase Chain Reaction methods, Sensitivity and Specificity, Phylogeny, Orthomyxoviridae Infections virology, Orthomyxoviridae Infections veterinary, Orthomyxoviridae Infections diagnosis, Swine Diseases virology, Swine Diseases diagnosis, Influenza A virus genetics, Influenza A virus isolation & purification, Influenza A virus classification
Abstract

Swine harbors a genetically diverse population of swine influenza A viruses (IAV-S), with demonstrated potential to transmit to the human population, causing outbreaks and pandemics. Here, we describe the development of a one-step, triplex real-time reverse transcription-polymerase chain reaction (rRT-PCR) assay that detects and distinguishes the majority of the antigenically distinct influenza A virus hemagglutinin (HA) clades currently circulating in North American swine, including the IAV-S H1 1A.1 (α), 1A.2 (β), 1A.3 (γ), 1B.2.2 (δ1) and 1B.2.1 (δ2) clades, and the IAV-S H3 2010.1 clade. We performed an in-field test at an exhibition swine show using in-field viral concentration and RNA extraction methodologies and a portable real-time PCR instrument, and rapidly identified three distinct IAV-S clades circulating within the N.A. swine population. Portable sequencing is used to further confirm the results of the in-field test of the swine triplex assay. The IAV-S triplex rRT-PCR assay can be easily transported and used in-field to characterize circulating IAV-S clades in North America, allowing for surveillance and early detection of North American IAV-S with human outbreak and pandemic potential.

Published
2024
Full Text
View/download PDF

18. Targeted amplification and genetic sequencing of the severe acute respiratory syndrome coronavirus 2 surface glycoprotein.

Author

Keller MW, Keong LM, Rambo-Martin BL, Hassell N, Lacek KA, Wilson MM, Kirby MK, Liddell J, Owuor DC, Sheth M, Madden J, Lee JS, Kondor RJ, Wentworth DE, and Barnes JR

Subjects
Humans, SARS-CoV-2 genetics, Pandemics, Membrane Glycoproteins, COVID-19 epidemiology, Vaccines
Abstract

Importance: The COVID-19 pandemic was accompanied by an unprecedented surveillance effort. The resulting data were and will continue to be critical for surveillance and control of SARS-CoV-2. However, some genomic surveillance methods experienced challenges as the virus evolved, resulting in incomplete and poor quality data. Complete and quality coverage, especially of the S-gene, is important for supporting the selection of vaccine candidates. As such, we developed a robust method to target the S-gene for amplification and sequencing. By focusing on the S-gene and imposing strict coverage and quality metrics, we hope to increase the quality of surveillance data for this continually evolving gene. Our technique is currently being deployed globally to partner laboratories, and public health representatives from 79 countries have received hands-on training and support. Expanding access to quality surveillance methods will undoubtedly lead to earlier detection of novel variants and better inform vaccine strain selection., Competing Interests: The authors declare no conflict of interest.

Published
2024
Full Text
View/download PDF

19. Genomic Surveillance for SARS-CoV-2 Variants: Predominance of the Delta (B.1.617.2) and Omicron (B.1.1.529) Variants - United States, June 2021-January 2022.

Author

Lambrou AS, Shirk P, Steele MK, Paul P, Paden CR, Cadwell B, Reese HE, Aoki Y, Hassell N, Zheng XY, Talarico S, Chen JC, Oberste MS, Batra D, McMullan LK, Halpin AL, Galloway SE, MacCannell DR, Kondor R, Barnes J, MacNeil A, Silk BJ, Dugan VG, Scobie HM, Wentworth DE, Caravas J, Kovacs NA, Gerhart JG, Jia Ng H, Beck A, Chau R, Cintron R, Cook PW, Gulvik CA, Howard D, Jang Y, Knipe K, Lacek KA, Moser KA, Paskey AC, Rambo-Martin BL, Nagilla RR, Retchless AC, Schmerer MW, Seby S, Shepard SS, Stanton RA, Stark TJ, Uehara A, Unoarumhi Y, Bentz ML, Burgin A, Burroughs M, Davis ML, Keller MW, Keong LM, Le SS, Lee JS, Madden Jr JC, Nobles S, Owuor DC, Padilla J, Sheth M, and Wilson MM

Subjects
Centers for Disease Control and Prevention, U.S., Genomics, Humans, Prevalence, Public Health Surveillance methods, United States epidemiology, COVID-19 epidemiology, COVID-19 virology, SARS-CoV-2 genetics
Abstract

Genomic surveillance is a critical tool for tracking emerging variants of SARS-CoV-2 (the virus that causes COVID-19), which can exhibit characteristics that potentially affect public health and clinical interventions, including increased transmissibility, illness severity, and capacity for immune escape. During June 2021-January 2022, CDC expanded genomic surveillance data sources to incorporate sequence data from public repositories to produce weighted estimates of variant proportions at the jurisdiction level and refined analytic methods to enhance the timeliness and accuracy of national and regional variant proportion estimates. These changes also allowed for more comprehensive variant proportion estimation at the jurisdictional level (i.e., U.S. state, district, territory, and freely associated state). The data in this report are a summary of findings of recent proportions of circulating variants that are updated weekly on CDC's COVID Data Tracker website to enable timely public health action. † The SARS-CoV-2 Delta (B.1.617.2 and AY sublineages) variant rose from 1% to >50% of viral lineages circulating nationally during 8 weeks, from May 1-June 26, 2021. Delta-associated infections remained predominant until being rapidly overtaken by infections associated with the Omicron (B.1.1.529 and BA sublineages) variant in December 2021, when Omicron increased from 1% to >50% of circulating viral lineages during a 2-week period. As of the week ending January 22, 2022, Omicron was estimated to account for 99.2% (95% CI = 99.0%-99.5%) of SARS-CoV-2 infections nationwide, and Delta for 0.7% (95% CI = 0.5%-1.0%). The dynamic landscape of SARS-CoV-2 variants in 2021, including Delta- and Omicron-driven resurgences of SARS-CoV-2 transmission across the United States, underscores the importance of robust genomic surveillance efforts to inform public health planning and practice., Competing Interests: All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. No potential conflicts of interest were disclosed.

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results