Search

Your search keyword '"Kinjo, Takeshi"' showing total 181 results
Start Over Author "Kinjo, Takeshi" Search Limiters Full Text
181 results on '"Kinjo, Takeshi"'

3. Treatment of ZC4H2 Variant-Associated Spastic Paraplegia with Selective Dorsal Rhizotomy and Intensive Postoperative Rehabilitation: A Case Report

Author

Inotani, Toshiki, primary, Horaguchi, Akira, additional, Morishita, Yuko, additional, Yoshida, Ayuko, additional, Otomo, Misaki, additional, Suzuki, Makoto, additional, Inui, Takehiko, additional, Okubo, Yukimune, additional, Komatsu, Shigemasa, additional, Mizuno, Chika, additional, Takahashi, Yuko, additional, Ochiai, Tatsuhiro, additional, Kinjo, Takeshi, additional, Asato, Takashi, additional, Takayama, Jun, additional, Tamiya, Gen, additional, Saijo, Naoya, additional, Kikuchi, Atsuo, additional, and Haginoya, Kazuhiro, additional

Published
2024
Full Text
View/download PDF

5. Clinical Utility of SARS-CoV-2 Antibody Titer Multiplied by Binding Avidity of Receptor-Binding Domain (RBD) in Monitoring Protective Immunity and Clinical Severity

Author

Takahashi, Etsuhisa, primary, Sawabuchi, Takako, additional, Homma, Tetsuya, additional, Fukuda, Yosuke, additional, Sagara, Hironori, additional, Kinjo, Takeshi, additional, Fujita, Kaori, additional, Suga, Shigeru, additional, Kimoto, Takashi, additional, Sakai, Satoko, additional, Kameda, Keiko, additional, and Kido, Hiroshi, additional

Published
2023
Full Text
View/download PDF

12. Molecular Epidemiological Characteristics of Mycobacterium abscessus Complex Derived from Non-Cystic Fibrosis Patients in Japan and Taiwan

Author

Yoshida, Mitsunori, primary, Chien, Jung-Yien, additional, Morimoto, Kozo, additional, Kinjo, Takeshi, additional, Aono, Akio, additional, Murase, Yoshiro, additional, Fujiwara, Keiji, additional, Morishige, Yuta, additional, Nagano, Hiroaki, additional, Jou, Ruwen, additional, Hasegawa, Naoki, additional, Ato, Manabu, additional, Hoshino, Yoshihiko, additional, Hsueh, Po-Ren, additional, and Mitarai, Satoshi, additional

Published
2022
Full Text
View/download PDF

18. A Case Report of Cerebral Meningitis Caused by Penicillin-Non-Susceptible Group B Streptococcus in an Immunocompromised Adult Patient

Author

Hirai, Jun, Kinjo, Takeshi, Haranaga, Shusaku, and Fujita, Jiro

Subjects
adult, PRGBS, meningitis, Case Report, serotype Ib, Streptococcus agalactiae, corticosteroids
Abstract

Streptococcus agalactiae, also known as Group B Streptococcus (GBS), is the leading cause of bacteremia and meningitis in neonates; however, it also causes meningitis in adults, although much less frequently. After the detection of penicillin-non-susceptible GBS (PRGBS) for the first time in 2008 by Japanese researchers, clinical PRGBS isolates have been reported worldwide. These isolates need to be given due attention for being non-susceptible to multiple drugs. Herein, we present the first clinical report of meningitis caused by PRGBS. A 41-year-old Japanese male receiving an immunosuppressant visited hospital complaining of fever. Although he did not have meningitis-related symptoms or physical findings, determination of the cause of fever by Gram-staining of the spinal fluid revealed gram-positive cocci in pairs and chains. Initially, he was hospitalized on the diagnosis of cerebral meningitis caused by Streptococcus pneumoniae. However, culture of the spinal fluid revealed the β-hemolytic colonies on blood agar. Biochemical testing and mass spectrometry revealed the isolated organism as GBS (serotype Ib). The minimum inhibitory concentration (MIC) of penicillin G for the isolated strain was 0.5 μg/mL, which is greater than the MIC criteria for “susceptibility” to penicillin G for beta-hemolytic streptococci according to Clinical and Laboratory Standards Institute standards. The isolated strain was also resistant to macrolide (MIC ≥ 8 μg/mL) and fluoroquinolone (MIC ≥ 8 μg/mL). The patient recovered without neurologic sequelae upon treatment with ceftriaxone, vancomycin, and corticosteroids for 4 days, and subsequently with ampicillin for 17 days. The rate of isolation of PRGBS in the clinics has gradually increased, particularly in Japan. Although PRGBS isolated in the present case was susceptible to ampicillin and cephalosporins, strains not susceptible to ampicillin, cefotaxime, and ceftriaxone have already been isolated, indicating the prospects for limited range of effective antibiotics against PRGBS infections, including meningitis, in the near future.

Published
2020

19. The First Case of Community-Acquired Pneumonia Due to Capsular Genotype K2-ST86 Hypervirulent Klebsiella pneumoniae in Okinawa, Japan: A Case Report and Literature Review

Author

Hirai, Jun, Sakanashi, Daisuke, Kinjo, Takeshi, Haranaga, Shusaku, and Fujita, Jiro

Subjects
hypervirulent Klebsiella pneumoniae, community-acquired pneumonia, Streptococcus pneumoniae, lobar pneumonia, Case Report, serotype K2, sequence type 86
Abstract

Hypervirulent Klebsiella pneumoniae (HV-KP) typically causes pyogenic liver abscess and bacteremia with metastatic infections. Community-acquired pneumonia (CAP) due to HV-KP is uncommon and details of its clinical and microbiological features are limited. We report the first case of CAP due to capsular genotype K2-ST86 HV-KP in Okinawa, Japan and review infections caused by the K2-ST86 strain. A 79-year-old woman presenting with fever and productive cough persisting for the past three days was admitted to hospital. Her vital signs indicated septic shock. Lung examination by auscultation revealed holo-crackle and lobar pneumonia in chest radiography, and Streptococcus pneumoniae was suspected. However, sputum and blood cultures revealed Gram-negative coccus identified as K. pneumoniae. Genetic analysis identified the isolated strain as the K2 serotype harboring rmpA, iutA, entB, and mrkD. Therefore, we identified the isolated strain as hypervirulent. The isolate belonged to ST86 as determined by multilocus sequence typing. The case was not complicated by predisposing factors such as diabetes mellitus and malignancy related to HV-KP infection; thus, this CAP-causing HV-KP strain may differ from the typical HV-KP strain that induces liver abscess. A literature review identified only nine cases with CAP due to HV-KP. In all cases, the disease mainly occurred in older males with diabetes mellitus, which makes the present case unusual, and had high rates of septic shock and death. No case, including ours, was complicated by metastatic infection, suggesting that CAP due to HV-KP poses little distant metastasis risk, even in patients with bloodstream infection. In our review, consistent with our case, K2-ST86 was the most common strain of HV-KP in patients with CAP. Therefore, studies are needed to elucidate the clinical and microbiological features of HV-KP CAP, with a focus on the K2-ST86 strain. Physicians should always consider K. pneumoniae in cases of sepsis CAP with lobar pneumonia.

Published
2020

20. Case Report of Primary Lung Abscesses Due to Hypervirulent Klebsiella pneumoniae (Serotype K2, Sequence Type 375): an Emerging Isolate in Okinawa, Japan

Author

Hirai, Jun, Sakanashi, Daisuke, Momose, Masashi, Koga, Tomomi, Kinjo, Takeshi, Haranaga, Shusaku, Motonaga, Eiji, and Fujita, Jiro

Subjects
hypervirulent Klebsiella pneumoniae, Okinawa, Japan, Case Report, sequence type 375, serotype K2, primary lung abscess
Abstract

Hypervirulent Klebsiella pneumoniae (HV-KP) is typically associated with community-acquired liver abscess and bacteremia with metastatic infection; however, primary lung abscess (PLA) caused by HV-KP is rare, with only one such case report to date. A 69-year-old man with a history of diabetes mellitus (DM) was admitted to hospital complaining of slight bloody sputum. Chest imaging showed multiple consolidations with cavities in both lung fields. A culture of bronchoalveolar lavage fluid confirmed the presence of K. pneumoniae. Genetic analyses identified the isolate as serotype K2 and sequence type 375 (K2-ST375), and that it harbored the rmpA gene. The patient was an Asian middle-aged male with DM, all of which are risk factors for HV-KP infection. Although complicating DM and the presence of the rmpA gene are more likely to induce disseminated infection, metastatic infections were not found in this patient. The clinical and microbiological characteristics of our patient were different from those of a previous reported case, although in both cases the patient was from Asia and had DM. Therefore, DM appears to be one of the predisposing factors for HV-KP lung abscesses and physicians should pay attention to emerging HV-KP lung abscess infection, particularly in Asian countries. Previous studies have also revealed that K2-ST375 is one of the major clones causing HV-KP infection, and that it is mainly isolated from patients with liver abscess. Interestingly, including the present case, most of the infectious cases caused by K2-ST375 have been reported from Okinawa Prefecture in Japan. Therefore, the trend of the K2-ST375 strain should be carefully monitored, particularly in Okinawa, Japan. The serotype of HV-KP that causes PLA is still unknown and further study is needed to elucidate the etiology of PLA due to HV-KP and the relationship between the strain K2-ST375 and PLA.

Published
2020

25. Critical respiratory failure in pregnancy complicated with COVID-19: A case report

Author

Chinen, Yukiko, primary, Kinjyo, Yoshino, additional, Mekaru, Keiko, additional, Kinjo, Tadatsugu, additional, Higure, Yuuri, additional, Kinjo, Takeshi, additional, Miyagi, Kazuya, additional, Yamada, Hisako, additional, Masamoto, Hitoshi, additional, Goya, Hideki, additional, Yoshida, Tomohide, additional, Maeshiro, Sakiko, additional, Nakamatsu, Masashi, additional, Fujita, Jiro, additional, and Aoki, Yoichi, additional

Published
2021
Full Text
View/download PDF

33. Diagnostic performance of serum interferon gamma, matrix metalloproteinases, and periostin measurements for pulmonary tuberculosis in Japanese patients with pneumonia

Author

Yamauchi, Momoko, primary, Kinjo, Takeshi, additional, Parrott, Gretchen, additional, Miyagi, Kazuya, additional, Haranaga, Shusaku, additional, Nakayama, Yuko, additional, Chibana, Kenji, additional, Fujita, Kaori, additional, Nakamoto, Atsushi, additional, Higa, Futoshi, additional, Owan, Isoko, additional, Yonemoto, Koji, additional, and Fujita, Jiro, additional

Published
2020
Full Text
View/download PDF

36. The counter regulatory response induced by CpG oligonucleotides prevents bleomycin induced pneumopathy

Author

Kinjo Takeshi, Tomaru Koji, Haines Diana C, and Klinman Dennis M

Subjects
Bleomycin, Pneumonitis, Fibrosis, CpG oligonucleotide, Diseases of the respiratory system, RC705-779
Abstract

Abstract Bleomycin (BLM) induces life-threatening pneumonitis and pulmonary fibrosis in 20% of patients, limiting its use as a chemotherapeutic agent. Oligonucleotides expressing immunostimulatory CpG motifs (CpG ODN) stimulate cells that express Toll-like receptor 9 to initiate an inflammatory response. This short-lived inflammation is physiologically suppressed by a counter-regulatory process that peaks five days later. Using a murine model of BLM-induced lung injury, the effect of CpG ODN treatment on pulmonary inflammation, fibrosis and mortality was examined. Administering CpG ODN 5 days before BLM (so that the peak of the counter-regulatory process induced by CpG ODN coincided with BLM delivery) resulted in a dose-dependent reduction in pulmonary toxicity (p

Published
2012
Full Text
View/download PDF

39. Use of steroids to treat anti-tumor necrosis factor α induced tuberculosis-associated immune reconstitution inflammatory syndrome: Case report and literature review.

Author

Daijiro Nabeya, Takeshi Kinjo, Kazutaka Yamaniha, Shoshin Yamazato, Reo Tome, Kazuya Miyagi, Hideta Nakamura, Tetsu Kinjo, Shusaku Haranaga, Futoshi Higa, Jiro Fujita, Nabeya, Daijiro, Kinjo, Takeshi, Yamaniha, Kazutaka, Yamazato, Shoshin, Tome, Reo, Miyagi, Kazuya, Nakamura, Hideta, Kinjo, Tetsu, and Haranaga, Shusaku

Published
2020
Full Text
View/download PDF

40. Comparison of two screening tests for HIV-Associated Neurocognitive Disorder suspected Japanese patients with respect to cART usage

Author

Kami-Onaga, Kaoru, primary, Tateyama, Masao, additional, Kinjo, Takeshi, additional, Parrott, Gretchen, additional, Tominaga, Daisuke, additional, Takahashi-Nakazato, Ai, additional, Nakamura, Hideta, additional, Tasato, Daisuke, additional, Miyagi, Kyoko, additional, Maeda, Saori, additional, Arae, Hirotaka, additional, Uehara, Hitoshi, additional, Miyagi, Kazuya, additional, Haranaga, Shusaku, additional, and Fujita, Jiro, additional

Published
2018
Full Text
View/download PDF

43. Additional file 2: Table 1. of Comparative epidemiology of influenza A and B viral infection in a subtropical region: a 7-year surveillance in Okinawa, Japan

Author

Iha, Yoshikazu, Kinjo, Takeshi, Parrott, Gretchen, Higa, Futoshi, Mori, Hideaki, and Fujita, Jiro

Abstract

Example weeks from dataset 1 and dataset 2 post-alignment. Sample weeks shown here are to serve as a visual representation of the method outlined to evaluate age distribution. Dataset 1 (left) and dataset 2 (right) were combined and aligned following the selection of “epidemic weeks”. A week in which influenza A or B cases accounted for more than 90 % of all positive influenza cases was defined as an epidemic week. In the year 2007, you see an example of a defined influenza A epidemic week, whereas the year 2011 is a representative influenza B epidemic week. The week from 2013 displays a typical week which was removed from our age distribution analysis because neither influenza A nor B was dominant (>90 %). (PPTX 66 kb)

Published
2016
Full Text
View/download PDF

45. Do infections with disseminated Mycobacterium avium complex precede sweet's syndrome? A case report and literature review

Author

Hibiya, Kenji, primary, Miyagi, Kazuya, additional, Tamayose, Maki, additional, Nabeya, Daijiro, additional, Kinjo, Takeshi, additional, Takeshima, Syo, additional, Ikemiyagi, Nanae, additional, Yamada, Keisuke, additional, Fujita, Akane, additional, Hashioka, Hiroe, additional, Kami, Wakaki, additional, Inamine, Morifumi, additional, Shibahara, Daisuke, additional, Nakamura, Hideta, additional, Furugen, Makoto, additional, Haranaga, Shusaku, additional, Higa, Futoshi, additional, Tateyama, Masao, additional, and Fujita, Jiro, additional

Published
2017
Full Text
View/download PDF

50. An Epidemiological Analysis of Summer Influenza Epidemics in Okinawa

Author

Sunagawa, Satoko, primary, Iha, Yoshikazu, additional, Taira, Katsuya, additional, Okano, Sho, additional, Kinjo, Takeshi, additional, Higa, Futoshi, additional, Kuba, Kazufumi, additional, Tateyama, Masao, additional, Nakamura, Katsunori, additional, Nakamura, Shota, additional, Motooka, Daisuke, additional, Horii, Toshihiro, additional, Parrott, Gretchen L., additional, and Fujita, Jiro, additional

Published
2016
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results