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In order to evaluate the antioxidant activity of evaporated ethanolic extract (EESB) and lyophilized water extract (WESB) of Shaggy bindweed ( Convulvulus betonicifolia Mill. Subs), some putative antioxidant methods such as DPPH· scavenging activity, ABTS •+ scavenging effect, ferric ions (Fe 3+ ) reduction method, cupric ions (Cu 2+ ) reducing capacity, and ferrous ions (Fe 2+ ) binding activities were separately performed. Also, ascorbic acid, α-tocopherol and BHT were used as the standard compounds. Additionally, some phenolic compounds that responsible for antioxidant abilities of EESB and WESB were screened by liquid chromatography-high resolution mass spectrometry (LC-HRMS). At the same concentration, EESB and WESB demonstrated effective antioxidant abilities when compared to standards. In addition, EESB demonstrated IC 50 values of 1.946 μg/mL against acetylcholinesterase (AChE), 0.815 μg/mL against α-glycosidase and 0.675 μg/mL against α-amylase enzymes., Competing Interests: The authors declare no conflict of interest., (© 2021 The Author(s).)

Kınkor ( Ferulago stell ata ) is Turkish medicinal plant species and used in folk medicine against some diseases. As far as we know, the data are not available on the biological activities and chemical composition of this medicinal plant. In this study, the phytochemical composition; some metabolic enzyme inhibition; and antidiabetic, anticholinergic, and antioxidant activities of this plant were assessed. In order to evaluate the antioxidant activity of evaporated ethanolic extract (EEFS) and lyophilized water extract (WEFS) of kınkor ( Ferulago stellata ), some putative antioxidant methods such as DPPH· scavenging activity, ABTS •+ scavenging activity, ferric ions (Fe 3+ ) reduction method, cupric ions (Cu 2+ ) reducing capacity, and ferrous ions (Fe 2+ )-binding activities were separately performed. Furthermore, ascorbic acid, BHT, and α-tocopherol were used as the standard compounds. Additionally, the main phenolic compounds that are responsible for antioxidant abilities of ethanol and water extracts of kınkor ( Ferulago stell ata ) were determined by liquid chromatography-high-resolution mass spectrometry (LC-HRMS). Ethanol and water extracts of kınkor ( Ferulago stell ata ) demonstrated effective antioxidant abilities when compared to standards. Moreover, ethanol extract of kınkor ( Ferulago stell ata ) demonstrated IC 50 values of 1.772 μg/mL against acetylcholinesterase (AChE), 33.56 ± 2.96 μg/mL against α-glycosidase, and 0.639 μg/mL against α-amylase enzyme respectively.