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14 results on '"Kotecha, Mrignayani"'

4. Corrigendum: Absolute oxygen-guided radiation therapy improves tumor control in three preclinical tumor models

Author

Gertsenshteyn, Inna, primary, Epel, Boris, additional, Giurcanu, Mihai, additional, Barth, Eugene, additional, Lukens, John, additional, Hall, Kayla, additional, Martinez, Jenipher Flores, additional, Grana, Mellissa, additional, Maggio, Matthew, additional, Miller, Richard C., additional, Sundramoorthy, Subramanian V., additional, Krzykawska-Serda, Martyna, additional, Pearson, Erik, additional, Aydogan, Bulent, additional, Weichselbaum, Ralph R., additional, Tormyshev, Victor M., additional, Kotecha, Mrignayani, additional, and Halpern, Howard J., additional

Published
2023
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5. Absolute oxygen-guided radiation therapy improves tumor control in three preclinical tumor models

Author

Gertsenshteyn, Inna, primary, Epel, Boris, additional, Giurcanu, Mihai, additional, Barth, Eugene, additional, Lukens, John, additional, Hall, Kayla, additional, Martinez, Jenipher Flores, additional, Grana, Mellissa, additional, Maggio, Matthew, additional, Miller, Richard C., additional, Sundramoorthy, Subramanian V., additional, Krzykawska-Serda, Martyna, additional, Pearson, Erik, additional, Aydogan, Bulent, additional, Weichselbaum, Ralph R., additional, Tormyshev, Victor M., additional, Kotecha, Mrignayani, additional, and Halpern, Howard J., additional

Published
2023
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6. Estimation of Domain Size in Nano Ferroelectrics from NMR T1 Measurements

Author

Shukla, Alok, Kotecha, Mrignayani, and Pandey, Lakshman

Subjects
Condensed Matter - Materials Science, Condensed Matter - Other Condensed Matter, Physics - Chemical Physics
Abstract

The spin lattice relaxation of I=3/2 quadrupolar spin system due to domain walls in order-disorder ferroelectrics has been studied and a general method is proposed for the measurement of domain width in nano ferroelectrics. Based on the fact that electric polarization undergoes spiral orientation as one moves from one domain to the other, it is assumed that at low temperatures the spins at and near domain walls undergo relaxation due to possible easy reorientation of electric polarization in domain walls even though such a relaxation in the main body of the domain has almost ceased. The spins present inside the domain undergo relaxation through transfer of magnetization to the domain walls through a spin diffusion process by nearest neighbour interaction. Rate equations for spin populations are formed by representing the ferroelectric domain by a one-dimensional chain of equidistant spins having dipolar coupling. Spin populations are calculated as a function of time for different ratios of quadrupolar to dipolar transition probabilities for a sample subjected to selective rf pulse. Expression for spin- lattice relaxation time T1 is derived in terms of domain width and ratio of quadrupolar to dipolar transition probabilities. It is found that the domain width can be estimated provided the value of spin lattice relaxation time T1 is known for the corresponding crystal with normal sized grains. The results are quite general and can be applied to any order disorder ferroelectric with nano sized domains and having spin I=3/2 nuclei., Comment: 31 pages, 5 figures, 1 table

Published
2008

10. An inverse-breathing encapsulation system for cell delivery

Author

Wang, Long-Hai, primary, Ernst, Alexander Ulrich, additional, Flanders, James Arthur, additional, Liu, Wanjun, additional, Wang, Xi, additional, Datta, Ashim K., additional, Epel, Boris, additional, Kotecha, Mrignayani, additional, Papas, Klearchos K., additional, and Ma, Minglin, additional

Published
2021
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12. The Application of Sodium Triple-Quantum Coherence NMR Spectroscopy for the Study of Growth Dynamics in Cartilage Tissue Engineering

Author

Kotecha, Mrignayani, Ravindran, Sriram, Schmid, Thomas M., Vaidyanathan, Aishwarya, George, Anne, and Magin, Richard L.

Subjects
Cartilage, Articular, Chondrocytes, Magnetic Resonance Spectroscopy, Tissue Engineering, Biomimetics, Sodium, Animals, Cattle, Article, Cells, Cultured, Cell Proliferation
Abstract

We studied the tissue growth dynamics for tissue-engineered cartilage at the early growth stage after cell seeding for four weeks using sodium triple-quantum coherence NMR spectroscopy. The following tissue-engineering constructs were studied: 1. Bovine chondrocytes cultured in alginate beads, 2. Bovine chondrocytes cultured as pellets (scaffold-free chondrocyte pellets), 3. Human Marrow Stromal Cells (HMSC) seeded in Collagen/Chitosan based scaffolds of chondrogenic extracellular matrix environment expecting chondrogenic differentiation, named as biomimetic scaffolds. We found that the sodium triple quantum coherence spectroscopy can differentiate between different tissue-engineering constructs and the native tissues based on the fast and the slow relaxation rates as well as based on the average quadrupolar coupling. Both the fast (Tf) and the slow (Ts) relaxation times were found to be longer in the chondrocyte pellets and the biomimetic scaffolds as compared to the chondrocytes suspended in alginate beads and the human articular cartilage tissues. In all cases, it was found that the relaxation rates and the motion of sodium ions, as measured from correlation time, were dependent on the amount of macromolecules, high cell density and the anisotropy of the cartilage tissue engineering constructs. Average quadrupolar couplings were found to be lower in the engineered tissue as compared to the native tissues, presumably due to the lack of order in collagen accumulated in the engineered tissue. These results indicate the use of sodium triple quantum coherence spectroscopy as a tool to investigate anisotropy and growth dynamics of cartilage tissue engineered constructs in a simple and reliable way.

Published
2013

14. An inverse-breathing encapsulation system for cell delivery.

Author

Long-Hai Wang, Ernst, Alexander Ulrich, Flanders, James Arthur, Wanjun Liu, Xi Wang, Datta, Ashim K., Epel, Boris, Kotecha, Mrignayani, Papas, Klearchos K., and Minglin Ma

Subjects
*RESPIRATION, *ISLANDS of Langerhans, *POLYMERSOMES, *BIOENGINEERING, *ELECTRON spin echoes, *KINETIC theory of gases
Published
2021
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