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40 results on '"Lin, Zixia"'

17. Loss of LncRNA DUXAP8 synergistically enhanced sorafenib induced ferroptosis in hepatocellular carcinoma via SLC7A11 de‐palmitoylation

Author

Shi, Zhehao, primary, Li, Zhiming, additional, Jin, Bin, additional, Ye, Wen, additional, Wang, Luhui, additional, Zhang, Sina, additional, Zheng, Jiuyi, additional, Lin, Zixia, additional, Chen, Bo, additional, Liu, Fangting, additional, Zhang, Baofu, additional, Ding, Xiwei, additional, Yang, Zhen, additional, Shan, Yunfeng, additional, Yu, Zhengping, additional, Wang, Yi, additional, Chen, Jicai, additional, Chen, Qiang, additional, Roberts, Lewis R., additional, and Chen, Gang, additional

Published
2023
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25. A Predictive Model Based on the Gut Microbiota Improves the Diagnostic Effect in Patients With Cholangiocarcinoma

Author

Zhang, Tan, primary, Zhang, Sina, additional, Jin, Chen, additional, Lin, Zixia, additional, Deng, Tuo, additional, Xie, Xiaozai, additional, Deng, Liming, additional, Li, Xueyan, additional, Ma, Jun, additional, Ding, Xiwei, additional, Liu, Yaming, additional, Shan, Yunfeng, additional, Yu, Zhengping, additional, Wang, Yi, additional, Chen, Gang, additional, and Li, Jialiang, additional

Published
2021
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26. Emerging role of PD-L1 modification in cancer immunotherapy

Author

Hu, Xiaoli, Lin, Zixia, Wang, Zhiwei, and Zhou, Qiangyong

Subjects
Review Article
Abstract

Accumulating evidence demonstrates that the expression levels of programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) are regulated at the various levels, including transcription, post-transcriptional modification and post-translational modifications (PTMs). The PTMs of PD-1/PD-L1 contain phosphorylation, ubiquitination, methylation, glycosylation and palmitoylation. Recently, PD-L1 was reported to be acetylated at Lys263 site by p300 and was deacetylated by histone deacetylase 2 (HDAC2). Acetylation of PD-L1 prevented its translocation to the nucleus and led to a reduction of the nuclear portion of PD-L1, resulting in evading immune surveillance of tumor cells. In this review article, we briefly describe the PTMs of PD-1/PD-L1 and mainly summarize the novel findings of PD-L1 acetylation in tumor cells. Moreover, we discuss the associations of PD-L1 acetylation and ubiquitination, phosphorylation and methylation. Furthermore, we highlight that targeting acetylation of PD-L1 by HDAC inhibitors might be useful for enhancing tumor immunotherapy.

Published
2021

27. The prognostic value of sarcopenia combined with preoperative fibrinogen–albumin ratio in patients with intrahepatic cholangiocarcinoma after surgery: A multicenter, prospective study

Author

Yu, Haitao, primary, Wang, Mingxun, additional, Wang, Yi, additional, Yang, Jinhuan, additional, Deng, Liming, additional, Bao, Wenming, additional, He, Bangjie, additional, Lin, Zixia, additional, Chen, Ziyan, additional, Chen, Kaiyu, additional, Zhang, Baofu, additional, Liu, Fangting, additional, Yu, Zhengping, additional, Ye, Longyun, additional, Jin, Bin, additional, and Chen, Gang, additional

Published
2021
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37. Formation of Ag3PO4/AgBr composites with Z-scheme configuration by an in situ strategy and their superior photocatalytic activity with excellent anti-photocorrosion performance.

Author

Zhuang, Jiajia, Huang, Yanfang, Liu, Jinsong, Zhu, Kongjun, Yan, Kang, Xu, Yuan, Wu, Zhengying, Li, Ziquan, and Lin, Zixia

Subjects
METHYLENE blue, COMPOSITE structures, AQUEOUS solutions, POLLUTANTS, TETRAHEDRA
Abstract

A novel Ag3PO4/AgBr composite with Z-Scheme structure was constructed and synthesized via a simple in situ ion-exchange strategy on the surface of Ag3PO4 tetrahedra in an alkaline environment. The as-prepared Ag3PO4/AgBr composite has an intimate contact interface and exhibited enhanced visible-light photocatalytic activity, accompanied by superior stability toward degradation of methylene blue (MB) in aqueous solution. Also, a variety of pollutants can be degraded without selectivity, and the degradation efficiency was over 96%. Changes in the bandgap and the detailed degradation mechanism of the Ag3PO4/AgBr composite were analyzed and revealed using characterization analysis, theoretical calculations, and further designed experiments. Sufficient interfacial contact between Ag3PO4 and AgBr was favorable for transferring carriers and lengthening the lifetime of the Z-Scheme system, which simultaneously inhibit photocorrosion and maintain a high degradation rate. The trapping experiments indicate that h+ is a dominant reactive species for the degradation of MB. This Ag3PO4/AgBr photocatalyst with Z-Scheme structure shows great potential for replication and large scale impact on the environmental purification of organic pollutants. [ABSTRACT FROM AUTHOR]

Published
2019
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39. Co-FeS 2 /CoS 2 Heterostructured Nanomaterials for pH Sensing.

Author

Gao, Yuan, Peng, Zehui, Wang, Ka, Yan, Shancheng, Lin, Zixia, Xu, Xin, and Shi, Yi

Subjects
NANOSTRUCTURED materials, TRANSITION metals, HYDROGEN evolution reactions
Abstract

Biosensors are widely used in production and life, and can be used in medicine, industrial production, and scientific research. Among them, the detection of pH has always received extensive attention. In this study, we demonstrate the use of a one-step hydrothermal method to prepare Co-FeS2/CoS2 nanomaterials as pH sensor (pH vs. overpotential) for the first time. The proposed pH sensor exhibits outstanding performance in KOH solutions via electrochemical methods with good stability. Overall, the results of this study not only add to the non-noble transition metal electrocatalysis research, but also identify important sensing characteristics for electrocatalysts. [ABSTRACT FROM AUTHOR]

Published
2020
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40. Implementing hybrid energy harvesting in 3D spherical evaporator for solar steam generation and synergic water purification

Author

Chunhua Lu, Deqi Fan, Haolan Xu, Huihua Min, Xiaofei Yang, Yi Lu, Zixia Lin, Lu, Yi, Fan, Deqi, Xu, Haolan, Min, Huihua, Lu, Chunhua, Lin, Zixia, and Yang, Xiaofei

Subjects
Materials science, Evaporator (marine), Energy Engineering and Power Technology, Portable water purification, 02 engineering and technology, 010402 general chemistry, 7. Clean energy, 01 natural sciences, Steam generation, nanocomposites, Electrical and Electronic Engineering, Process engineering, solar evaporation, business.industry, Hybrid energy, 021001 nanoscience & nanotechnology, 6. Clean water, Atomic and Molecular Physics, and Optics, 0104 chemical sciences, Electronic, Optical and Magnetic Materials, photothermal materials, 13. Climate action, 0210 nano-technology, business, MXene, water purification
Abstract

Solar‐powered water evaporation provides a promising strategy for eco‐friendly and cost‐effective freshwater production. The exploration of high‐performance photothermal materials and rational design of evaporation architectures are crucial in promoting the solar steam generation efficiency. Herein, multi‐dimensional MXene‐based composites with well‐organized heterojunction nanostructures are proposed as bifunctional photothermal materials. The solar thermal conversion, chemical stability and photocatalysis degradation properties were enhanced by anchoring Co3O4 nanoparticles on delaminated ultrathin MXene nanosheets, compared to that of Ti3C2 MXene. Based these advantages, an integrated 3D spherical evaporator is constructed using the Co3O4/Ti3C2 MXene based fabric. The evaporator shows its distinct advantages in maximizing the harvest of the hybrid energy from sunlight and the ambient environment, making it ideal for solar steam generation and synergetic water purification. An extremely high evaporation rate of 1.89 kg m−2 h−1 with a corresponding light‐to‐vapor energy conversion efficiency beyond the theoretical limit (130.4%) is achieved. More importantly, while the evaporation rate of the 2D evaporator significantly recedes upon the oblique sunlight irradiation, the evaporation rate of the 3D spherical evaporator is constantly high at different incident angles of sunlight, which satisfies the requirement of practical applications under moving sun. Refereed/Peer-reviewed

Published
2020

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