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16 results on '"Liu, Xin-jian"'

6. Gluten ataxia of sporadic and hereditary cerebellar ataxia in patients from mainland China

Author

Guan, Wen-Juan, Liu, Xin-Jian, Tang, Bei-Sha, Liu, Yu-Tao, Zhou, Ying, Jiang, Hong, Shen, Lu, Xia, Kun, and Wang, Jun-Ling

Subjects
China -- Health aspects, Gluten -- Health aspects, Viral antibodies -- Properties, Antibodies -- Properties, Cerebellar ataxia -- Distribution -- Diagnosis -- Care and treatment, Company distribution practices, Health
Abstract

Byline: Wen-Juan. Guan, Xin-Jian. Liu, Bei-Sha. Tang, Yu-Tao. Liu, Ying. Zhou, Hong. Jiang, Lu. Shen, Kun. Xia, Jun-Ling. Wang Background: Gluten sensitivity (GS) is a spectrum of disorders with diverse [...]

Published
2013

8. Additional file 2: Figure S1. of Activation of the hypothalamic-pituitary-adrenal (HPA) axis contributes to the immunosuppression of mice infected with Angiostrongylus cantonensis

Author

Chen, Ai-Ling, Sun, Xi, Wang, Wei, Liu, Jin-Feng, Zeng, Xin, Qiu, Jing-Fan, Liu, Xin-Jian, and Wang, Yong

Abstract

RU486 treatment did not reverse impairment of thymocyte development in A. cantonensis-infected mice. Mice were infected with A. cantonensis first and treated with RU486 daily since 10 dpi until sacrificed. Proportion of thymocyte subsets was detected. Each group contained 4–6 mice. Values were shown as mean ± SEM. A two-tailed t test was used for statistical analysis. *, results differed from the control group; **P

Published
2016
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11. Prevalence of Spina Bifida Occulta and Its Relationship With Overactive Bladder in Middle-Aged and Elderly Chinese People

Author

Wu, Jun Wei, primary, Xing, Yu Rong, additional, Wen, Yi Bo, additional, Li, Tian Fang, additional, Xie, Jia Feng, additional, Feng, Quan De, additional, Shang, Xiao Ping, additional, Li, Yun Long, additional, Feng, Jin Jin, additional, Wang, Xin Xin, additional, Zhai, Rong Qun, additional, He, Xiang Fei, additional, Chen, Tao, additional, Liu, Xin Jian, additional, and Wen, Jian Guo, additional

Published
2016
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12. Molecular dynamics simulation of the thermophysical properties and phase change behaviors of aluminum nanoparticles

Author

Lin Chang-Peng, Liu Xin-Jian, and Rao Zhong-Hao

Subjects
Molecular dynamics, Phase change, Materials science, chemistry, Chemical engineering, Aluminium, General Physics and Astronomy, chemistry.chemical_element, Nanoparticle
Abstract

With the development of energy storage technology, phase change materials which can be used to store thermal energy have received much attention in recent years. The nano-metallic materials are universally used as phase change materials due to their many desirable thermophysical properites. In this paper, the molecular dynamics simulation method is adopted to simulate the variations of melting point, density and phonon thermal conductivity of the nano aluminum with grain size ranging from 0.8 nm to 3.2 nm. The variations of density, specific heat capacity and phonon thermal conductivity with temperature of aluminum nanoparticles at a grain size of 1.6 nm are also studied. By using the embedded-atom potential, the thermophysical properties and phase change behaviors of aluminum nanoparticles are stimulated. The phase transition temperature of aluminum nanoparticles is studied based on the energy-temperature curve and the specific heat capacity-temperature curve. The surface energy theory and the size effect theory are applied to the analysis of the variation of the melting point of the aluminum nanoparticles, and the results show that the melting point increases as grain size augments, and it increases slowly when its grain size is between 2.2 nm and 3.2 nm but still holds the trend of increase. In order to obtain accurate thermal conductivity, the Green-Kubo method is adopted to calculate the phonon thermal conductivity of aluminum nanoparticle. As the grain size of aluminum nanoparticles increases, its density monotonically decreases, and the thermal conductivity monotonically increases linearly, which is in line with the theory of phonon. Similarly, with the increase of temperature, the density and thermal conductivity of aluminum nanoparticles of 1.6 nm in grain size both decrease. Moreover, the density of aluminum nanoparticle is generally lower than that of its bulk material. The study also shows that the heat transfer manner of aluminum nanoparticle is based on ballistic-diffusive heat conduction instead of the traditional diffusive heat conduction when it is in a nanoscale. The simulation studies the thermophysical properties of nanoparticles from the atomic perspective, and is of significance for guiding the design of the phase change materials based on the aluminum nanoparticles for thermal energy storage.

Published
2015

14. MHC II−, but not MHC II+, hepatic Stellate cells contribute to liver fibrosis of mice in infection with Schistosoma japonicum.

Author

Zhou, Chun-Lei, Kong, De-Long, Liu, Jin-Feng, Lu, Zhong-Kui, Guo, Hong-Fei, Wang, Wei, Qiu, Jing-Fan, Liu, Xin-Jian, and Wang, Yong

Subjects
*KUPFFER cells, *SCHISTOSOMA japonicum, *MAJOR histocompatibility complex, *MYOFIBROBLASTS, *LABORATORY mice
Abstract

Hepatic stellate cells (HSCs) are considered as the main effector cells in vitamin A metabolism and liver fibrosis, as well as in hepatic immune regulation. Recently, researches have revealed that HSCs have plasticity and heterogeneity, which depend on their lobular location and whether liver is normal or injured. This research aimed to explore the biological characteristics and heterogeneity of HSCs in mice with Schistosoma japonicum ( S. japonicum ) infection, and determine the subpopulation of HSCs in pathogenesis of hepatic fibrosis caused by S. japonicum infection. Results revealed that HSCs significantly increased the expressions of MHC II and fibrogenic genes after S. japonicum infection, and could be classified into MHC II + HSCs and MHC II − HSCs subsets. Both two HSCs populations suppressed the proliferation of activated CD4 + T cells, whereas only MHC II − HSCs displayed a myofibroblast-like phenotype. In response to IFN-γ, HSCs up-regulated the expressions of MHC II and CIITA , while down-regulated the expression of fibrogenic gene Col1 . In addition, praziquantel treatment decreased the expressions of fibrogenic genes in MHC II − HSCs. These results confirmed that HSCs from S. japonicum -infected mice have heterogeneity. The MHC II − α-SMA + HSCs were major subsets of HSCs contributing to liver fibrosis and could be considered as a potential target of praziquantel anti-fibrosis treatment. [ABSTRACT FROM AUTHOR]

Published
2017
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15. Melamine-contaminated milk formula and its impact on children.

Author

Jian Guo Wen, Xin Jian Liu, Zhi Min Wang, Tian Fang Li, Wahlqvist, Mark L., Wen, Jian Guo, Liu, Xin Jian, Wang, Zhi Min, and Li, Tian Fang

Subjects
*MELAMINE, *KIDNEY stones, *KIDNEY failure, *INFANT formulas, *CHILD mortality, *CARCINOGENS, *FOOD, *FOOD contamination, *HETEROCYCLIC compounds, *KIDNEY diseases, *MILK, *URINARY calculi, *URINARY organs, *FOOD safety, *TUMORS
Abstract

The melamine contaminated milk powder contamination scandal occurred in China in 2008. Its main consequences so far have been urinary stone formation in children with associated renal damage and increased child mortality. Eight years have passed, but food safety issues still remain of concern in the daily lives of millions of Chinese. Vigilance is required to ensure no recurrence of such food safety problems. Ongoing studies focus on the early detection of food industry malpractice, mechanisms whereby these toxic substances induce disease and how its advent may be prevented and better managed. Melamine undergoes renal excretion, but is metabolized slowly and excreted largely unchanged in the urine. Urinary melamine measurement may provide a rapid and inexpensive way to identify exposure to melamine adulterated food items. Although most patients with melaminerelated urinary stones (MUS) have been responsive to conservative treatment, longer time follow-up is needed to assess chronic effects. Aside from MUS, melamine is a recognized carcinogen and can induce urinary tract tumours. Very little is known about the effects of excessive exposure to melamine contaminated milk powder in infants on growth, adolescent and adult health, although short-term effects have become apparent during the scandal. [ABSTRACT FROM AUTHOR]

Published
2016
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