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8. Quality Evaluation of Tetrastigmae Radix from Two Different Habitats Based on Simultaneous Determination of Multiple Bioactive Constituents Combined with Multivariate Statistical Analysis

Author

Chen, Haijie, primary, Zhou, Yongyi, additional, Xue, Jia, additional, Yuan, Jiahuan, additional, Cai, Zhichen, additional, Wu, Nan, additional, Zou, Lisi, additional, Yin, Shengxin, additional, Yang, Wei, additional, Liu, Xunhong, additional, Cheng, Jianming, additional, and Tang, Li, additional

Published
2022
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9. Qualitative Analysis and Componential Differences of Chemical Constituents in Lysimachiae Herba from Different Habitats (Sichuan Basin) by UFLC-Triple TOF-MS/MS

Author

Zhou, Yongyi, primary, Chen, Haijie, additional, Xue, Jia, additional, Yuan, Jiahuan, additional, Cai, Zhichen, additional, Wu, Nan, additional, Zou, Lisi, additional, Yin, Shengxin, additional, Yang, Wei, additional, Liu, Xunhong, additional, Chen, Jianming, additional, and Liu, Fushuangshuang, additional

Published
2022
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10. Comparative Study on Chemical Constituents of Medicinal and Non-Medicinal Parts of Flos Abelmoschus manihot, Based on Metabolite Profiling Coupled with Multivariate Statistical Analysis

Author

Yin, Shengxin, primary, Cai, Zhichen, additional, Chen, Cuihua, additional, Mei, Yuqi, additional, Wei, Lifang, additional, Liu, Shengjin, additional, Zou, Lisi, additional, Wu, Nan, additional, Yuan, Jiahuan, additional, Liu, Xunhong, additional, Ge, Haitao, additional, Wang, Dianguang, additional, and Wang, Dandan, additional

Published
2022
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11. Qualitative Analysis and Componential Differences of Chemical Constituents in Taxilli Herba from Different Hosts by UFLC-Triple TOF-MS/MS

Author

Yuan, Jiahuan, primary, Li, Li, additional, Cai, Zhichen, additional, Wu, Nan, additional, Chen, Cuihua, additional, Yin, Shengxin, additional, Liu, Shengjin, additional, Wang, Wenxin, additional, Mei, Yuqi, additional, Wei, Lifang, additional, Liu, Xunhong, additional, Zou, Lisi, additional, and Chen, Haijie, additional

Published
2021
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12. Metabolite Profiling and Transcriptome Analysis Explains Difference in Accumulation of Bioactive Constituents in Licorice (Glycyrrhiza uralensis) Under Salt Stress

Author

Wang, Chengcheng, primary, Chen, Lihong, additional, Cai, Zhichen, additional, Chen, Cuihua, additional, Liu, Zixiu, additional, Liu, Shengjin, additional, Zou, Lisi, additional, Tan, Mengxia, additional, Chen, Jiali, additional, Liu, Xunhong, additional, Mei, Yuqi, additional, Wei, Lifang, additional, Liang, Juan, additional, and Chen, Jine, additional

Published
2021
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18. Comparative Metabolite Profiling of Wild and Cultivated Licorice Based on Ultra-Fast Liquid Chromatography Coupled with Triple Quadrupole-Time of Flight Tandem Mass Spectrometry

Author

Wang, Chengcheng, primary, Cai, Zhichen, additional, Shi, Jingjing, additional, Chen, Shuyu, additional, Tan, Mengxia, additional, Chen, Jiali, additional, Chen, Lihong, additional, Zou, Lisi, additional, Chen, Cuihua, additional, Liu, Zixiu, additional, and Liu, Xunhong, additional

Published
2019
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20. Qualitative and Quantitative Analysis of the Saponins in Panacis Japonici Rhizoma Using Ultra-Fast Liquid Chromatography Coupled with Triple Quadrupole-Time of Flight Tandem Mass Spectrometry and Ultra-Fast Liquid Chromatography Coupled with Triple Quadrupole-Linear Ion Trap Tandem Mass Spectrometry

Author

Chen, Jiali, primary, Tan, Mengxia, additional, Zou, Lisi, additional, Liu, Xunhong, additional, Chen, Shuyu, additional, Shi, Jingjing, additional, Chen, Cuihua, additional, Wang, Chengcheng, additional, and Mei, Yuqi, additional

Published
2019
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26. Comparison of Chemical Constituents in Magnoliae Officinalis Cortex Processed by 'Sweating' and 'Non Sweating' based on Ultra Fast Liquid Chromatography-Triple Quadrupole-Time of Flight Mass Spectrometry and Gas Chromatography-Triple Quadrupole Mass Spectrometry Combined with Multivariate Statistical Analysis

Author

Zhao Hui, Shi JingJing, Yan Ying, Wang ChengCheng, Zou Lisi, Chen ShuYu, and Liu Xunhong

Subjects
Pharmacology, Chromatography, 010405 organic chemistry, Chemistry, Plant Science, General Medicine, 01 natural sciences, 0104 chemical sciences, Triple quadrupole mass spectrometer, 010404 medicinal & biomolecular chemistry, Complementary and alternative medicine, Triple quadrupole mass spectrometry, Chemical constituents, Drug Discovery, Ultra fast, Gas chromatography, Time-of-flight mass spectrometry, Multivariate statistical, Gas chromatography–mass spectrometry
Abstract

Magnoliae Officinalis Cortex (MOC) is a commonly used traditional Chinese herbal medicine, which is always preliminarily processed by “sweating”. To explore the effects of primary processing on chemical constituents in MOC and the potential chemical markers for differentiating the samples processed by “sweating” and “non sweating”, a method is proposed based on ultra fast liquid chromatography-triple quadrupole-time of flight mass spectrometry (UFLC-Triple TOF MS/MS) and gas chromatography-triple quadrupole mass spectrometry (GC-MS/MS) coupled with multivariate statistical analysis. The obtained data were analyzed by principal component analysis and partial least-squares discriminant analysis. The nonvolatile constituents were identified according to MS accurate mass and MS/MS spectrometry fragmentation information, combined with the software of database search and literatures comparison. The volatile constituents were identified according to the NIST05 library and literatures. All of the results demonstrated that the chemical constituents in MOC samples processed by “sweating” and “non sweating” were clearly distinguished. Seventeen nonvolatile differential constituents and five volatile differential constituents were identified and presented in different change laws. This study will provide the basic information for revealing the difference of chemical constituents in MOC processed by “sweating” and “non sweating” and comprehensive evaluation of its quality.

Published
2018

33. A Method to Study the Distribution Patterns for Metabolites in Xylem and Phloem of Spatholobi Caulis.

Author

Mei, Yuqi, Wei, Lifang, Chai, Chuan, Zou, Lisi, Liu, Xunhong, Chen, Jiali, Tan, Mengxia, Wang, Chengcheng, Cai, Zhichen, Zhang, Furong, Yin, Shengxin, Shellie, Robert, and Cacciola, Francesco

Subjects
PHENOLIC acids, ISOFLAVONES, PHLOEM, XYLEM, CHALCONE, CHINESE medicine, PRINCIPAL components analysis, METABOLITES
Abstract

Spatholobi Caulis (SC), the vine stem of Spatholobus suberectus Dunn, is a widely used traditional Chinese medicine (TCM) for the treatment of blood stasis syndrome and related diseases. Xylem and phloem are the main structures of SC and the color of xylem in SC is red brown or brown while the phloem with resin secretions is reddish brown to dark brown. They are alternately arranged in a plurality of concentric or eccentric rings. In order to investigate the distribution patterns of metabolites in xylem and phloem of SC, an analytical method based on UFLC–QTRAP–MS/MS was established for simultaneous determination of 22 constituents including four flavanols, nine isoflavones, two flavonols, two dihydroflavones, one flavanonol, one chalcone, one pterocarpan, one anthocyanidin and one phenolic acid in the samples (xylem and phloem) from Laos. Furthermore, according to the contents of 22 constituents, heat map, principal components analysis (PCA), orthogonal partial least squares discriminant analysis (OPLS–DA) and t–test were used to evaluate the samples and discover the differences between xylem and phloem of SC. The results indicated that the measured ingredients in xylem and phloem were significantly different. To be specific, the contents of flavonoids in xylem were higher than that in phloem, while the content of protocatechuic acid showed a contrary tendency. This study will not only reveal the distribution patterns of metabolites in xylem and phloem of SC but also facilitate further study on their quality formation. [ABSTRACT FROM AUTHOR]

Published
2020
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