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IntroductionSevere acute respiratory syndrome coronavirus 2 also called coronavirus disease 2019 was first reported in the African continent on 14 February 2020 in Egypt. As at 18 December 2020, the continent reported 2,449,754 confirmed cases, 57,817 deaths and 2,073,214 recoveries. Urban cities in Africa have particularly suffered the brunt of coronavirus disease 2019 coupled with criticisms that the response strategies have largely been a 'one-size-fits-all' approach. This article reviewed early evidence on urban health nexus with coronavirus disease 2019 preparedness and response in Africa.MethodsA rapid scoping review of empirical and grey literature was done using data sources such as ScienceDirect, GoogleScholar, PubMed, HINARI and official websites of World Health Organization and Africa Centres for Disease Control and Prevention. A total of 26 full articles (empirical studies, reviews and commentaries) were synthesised and analysed qualitatively based on predefined inclusion criteria on publication relevance and quality.ResultsOver 70% of the 26 articles reported on coronavirus disease 2019 response strategies across Africa; 27% of the articles reported on preparedness towards coronavirus disease 2019, while 38% reported on urbanisation nexus with coronavirus disease 2019; 40% of the publications were full-text empirical studies, while the remaining 60% were either commentaries, reviews or editorials. It was found that urban cities remain epicentres of coronavirus disease 2019 in Africa. Even though some successes have been recorded in Africa regarding coronavirus disease 2019 fight, the continent's response strategies were largely found to be a 'one-size-fits-all' approach. Consequently, adoption of 'Western elitist' mitigating measures for coronavirus disease 2019 containment resulted in excesses and spillover effects on individuals, families and economies in Africa.ConclusionAfrica needs to increase commitment to health systems strengthening through context-specific interventions and prioritisation of pandemic preparedness over response. Likewise, improved economic resilience and proper urban planning will help African countries to respond better to future public health emergencies, as coronavirus disease 2019 cases continue to surge on the continent.

Background: Female Genital Schistosomiasis (FGS) remains a critical and yet neglected topics in Neglected Tropical Diseases (NTDs), significantly affecting the health of women and girls worldwide. Health workers' knowledge of FGS is vital to the prevention and management of the disease. This study adopted an implementation research approach to identify and address the existing knowledge gap regarding FGS among healthcare workers in Ghana. Methods: This study was a 3-year (2020–2022) implementation research applying a pragmatic uncontrolled quasi-experimental study design. The study involved a baseline assessment, FGS training intervention for health workers and student nurses, distribution of FGS educational materials, and an endline assessment. A mixed-method approach was applied to data collection involving health workers from two schistosomiasis endemic districts and across the country. NVIVO 12 and STATA 14 were used for qualitative and quantitative data analysis, respectively. Results: Prior to the intervention, the level of awareness about FGS among health workers was less than 8%, and most participants only understood FGS as merely urogenital schistosomiasis in females. In response to this gap, an FGS education intervention in the form of training of health workers, student nurses alongside the distribution of FGS educational materials were carried out. The intervention enhanced health workers' awareness of FGS to more than 61%, encompassing an enhanced understanding of the disease's signs and symptoms to more than 60%, as well as its management strategies. However, access to praziquantel, the primary treatment, remained a significant challenge. Conclusions: The FGS intervention effectively raised healthcare workers' awareness and knowledge. Expanding training and improving praziquantel access are essential for optimal FGS management. A multi-faceted approach involving individuals, communities, and the healthcare system is necessary for comprehensive FGS prevention and control. Author summary: This study addresses Female Genital Schistosomiasis (FGS), a critical yet neglected issue among Neglected Tropical Diseases (NTDs), particularly impacting women and girls globally. Enhancing healthcare workers' knowledge of FGS is crucial for effective prevention and management. The research, conducted over three years in Ghana from 2020 to 2022, utilized an implementation research approach. Initially, baseline assessments revealed alarmingly low awareness (less than 8%) among health workers, who often equated FGS with urogenital schistosomiasis in females. In response, a comprehensive intervention was implemented, including training sessions and distribution of educational materials. This intervention significantly increased awareness among health workers to over 61%, and improved understanding of FGS signs, symptoms, and management strategies to over 60%. Despite these gains, challenges persist, notably in ensuring access to praziquantel, the primary treatment for schistosomiasis. The study underscores the need for ongoing training initiatives and enhanced medication accessibility to bolster FGS management. It concludes with a call for a holistic approach involving all stakeholders—individuals, communities, and healthcare systems—to advance knowledge and management of FGS effectively. [ABSTRACT FROM AUTHOR]

Background: Low birth weight (LBW) is one of the major factors affecting child morbidity and mortality worldwide. It also results in substantial costs to the health sector and imposes a significant burden on the society as a whole. This study seeks to investigate the determinants of low birth weight and the incidence of LBW in southern rural Ghana.Methods: Pregnancy, birth, demographic and socioeconomic information of 6777 mothers who gave birth in 2011, 2012, and 2013 and information on their babies were extracted from a database. The database of Dodowa Health and Demographic Surveillance System is a longitudinal follow-up of over 24,000 households. The incidence of LBW was calculated and the univariable and multivariable associations between exposure variables and outcome were explored using logistic regression. STATA 11 was used for the analyses.Result: The results revealed that 40.21 % of the infants were not weighed at birth and the incidence of LBW for 2011 to 2013 was 8.72, 7.04 and 7.52 % respectively. Women aged 20-24, 25-29, 30-34 years were more than twice more likely to have babies weighing ≥2.5 kg compared to those <20 years (OR:2.32, 95 % CI:1.65-3.26, OR:2.73, 95 % CI:1.96-3.79, OR:2.87, 95 % CI:2.06-4.01) and mothers who were >34 years were more than three times more likely to have babies weighed ≥2.5 kg (OR: 3.59, 95 % CI:2.56-5.04). Mothers who were civil servants were 77 % more likely to have babies weighed ≥2.5 kg (OR: 1.77, 95 % CI: 1.99-2.87) compared to those who were unemployed. After adjusting for other explanation variables, mothers from poorer households were 30 % more likely to have babies who weighed ≥2.5 kg (OR: 1.30, 95 % CI: 1.01-1.66) compared to those from the poorest households. Women with parity2 and parity > 3 were 30 % and 81 % more likely to have babies weighing ≥2.5 kg (OR: 1.30, 95 % CI: 1.03-1.63, OR: 1.81, 95 % CI: 1.38-2.35) compared to those with parity1. Male infants were 52 % more likely to weigh ≥2.5 kg at birth (OR: 1.52, 95 % CI: 1.32-1.76) compared to females.Conclusion: Our study revealed that having infant birth weight ≥ 2.5 kg is highly associated with socioeconomic status of women household, the gender of an infant, parity, occupation and maternal age. [ABSTRACT FROM AUTHOR]

Background: Data needed to estimate causes of death and the pattern of these deaths are scarce in sub-Saharan Africa. Such data are very important for targeting, monitoring, and evaluating health interventions. Objective: To estimate the mortality rate and determine causes of death among adults (aged 15 years and older) in a rural district of southern Ghana, using the InterVA-4 model. Design: Data used were generated from verbal autopsies conducted for registered adult members of the Dodowa Health and Demographic Surveillance System who died between 2006 and 2010. The InterVA-4 model was used to assign the cause of death. Results: Overall, the mortality rate for the period under review was 7.5/1,000 person-years (py) for the general population and 10.4/1,000 py for those aged 15 and older. The leading cause of death was communicable diseases (CDs), with a malaria-specific mortality rate of 1.06/1,000 py. Pulmonary tuberculosis (TB)-specific mortality rate was the next highest (1.01/1,000 py). HIV/AIDS attributed deaths were lower among males than females. Non-communicable diseases (NCDs) contributed to 28.3% of the deaths with cause-specific mortality rate of 2.93/1,000 py. Stroke topped the list with cause-specific mortality rate of 0.69/1,000 py. As expected, young males (15-49 years) contributed to more road traffic accident (RTA) deaths; they had a lower RTA cause-specific mortality rate than older males (50-64 years). Conclusions: Data indicate that CDs (e.g. malaria and TB) remain the major cause of death with NCDs (e.g. stroke) following closely behind. Verbal autopsy data can provide the causes of mortality in poorly resourced settings where access to timely and accurate data is scarce. [ABSTRACT FROM AUTHOR]