198 results on '"Morello, E"'
Search Results
2. Investigating the Impact of Heat Stress and Green Space Accessibility for At-Risk Communities.
- Author
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Zendeli, D, Colaninno, N, and Morello, E
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- 2023
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Catalog
3. P1450: AUTOLOGOUS STEM CELL TRANSPLANTATION INDUCES HIGHER LEVEL OF EXHAUSTED T-CELLS IN DLBCL PATIENTS BEFORE LEUKAPHERESIS FOR CAR-T CELL THERAPY.
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Farina, M., primary, Chiarini, M., additional, Almici, C., additional, Beghin, A., additional, Accorsi Buttini, E., additional, Galvagni, A., additional, Ferrari, E., additional, Bianchetti, A., additional, Zuccalà, F., additional, Piva, S., additional, Volonghi, I., additional, Poli, L., additional, Moratto, D., additional, Leoni, A., additional, Re, F., additional, Bosio, K., additional, Bernardi, S., additional, Polverelli, N., additional, Turra, A., additional, Morello, E., additional, Cattaneo, C., additional, Lanfranchi, A., additional, Malagola, M., additional, Brugnoni, D., additional, Re, A., additional, and Russo, D., additional more...
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- 2022
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4. PB2209: HIGH RISK MYELODYSPLASTIC SYNDROME DEVELOPING IN A PATIENT AFTER CHIMERIC ANTIGEN RECEPTOR (CAR) T- CELL THERAPY FOR RELAPSED DIFFUSE LARGE B CELL LYMPHOMA
- Author
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Accorsi Buttini, E., primary, Farina, M., additional, Turra, A., additional, Morello, E., additional, Polverelli, N., additional, Colnaghi, F., additional, Almici, C., additional, Ferrari, E., additional, Bianchetti, A., additional, Leoni, A., additional, Re, F., additional, Bosio, K., additional, Bernardi, S., additional, Malagola, M., additional, Re, A., additional, and Russo, D., additional more...
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- 2022
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5. Prognostic impact of bone invasion in canine oral malignant melanoma treated by surgery and anti-CSPG4 vaccination: A retrospective study on 68 cases (2010–2020)
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Camerino, M., Giacobino, D., Manassero, L., Iussich, S., Riccardo, F., Cavallo, F., Tarone, L., Olimpo, M., Lardone, E., Martano, M., Del Magno, S., Buracco, P., and Morello, E.
- Subjects
anti-CSPG4 electrovaccination ,bone invasion ,dog ,oral melanoma ,prognosis ,surgery - Published
- 2022
6. Case Report: Late Onset of Myelodysplastic Syndrome From Donor Progenitor Cells After Allogeneic Stem Cell Transplantation. Which Lessons Can We Draw From the Reported Case?
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Farina, M, Bernardi, S, Gandolfi, L, Zanaglio, C, Morello, E, Turra, A, Zollner, T, Gramegna, D, Rambaldi, B, Cattina, F, Polverelli, N, Malagola, M, Russo, D, Farina M., Bernardi S., Gandolfi L., Zanaglio C., Morello E., Turra A., Zollner T., Gramegna D., Rambaldi B., Cattina F., Polverelli N., Malagola M., Russo D., Farina, M, Bernardi, S, Gandolfi, L, Zanaglio, C, Morello, E, Turra, A, Zollner, T, Gramegna, D, Rambaldi, B, Cattina, F, Polverelli, N, Malagola, M, Russo, D, Farina M., Bernardi S., Gandolfi L., Zanaglio C., Morello E., Turra A., Zollner T., Gramegna D., Rambaldi B., Cattina F., Polverelli N., Malagola M., and Russo D. more...
- Abstract
Background: Myelodysplastic syndromes and acute leukemias after allogeneic stem cell transplantation (allo-SCT) are mainly caused by recurrence of the primitive leukemic clones. More rarely, they originate from donor hematopoietic stem cells, developing the so-called donor cell leukemia (DCL) or myelodysplastic syndromes (DC-MDSs). DCL and DC-MDS can be considered as an in vivo model of leukemogenesis, and even if the pathogenetic mechanisms remain speculative, a genetic predisposition of donor progenitor cells, an altered host microenvironment, and the impairment of immune surveillance are considered the main causes. Case Presentation: We report a case of DC-MDS diagnosed 5 years after an allo-SCT from a matched related donor (patient’s sister) in a patient with Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia (Ph+ B-ALL). The sex-mismatch allowed us to identify the donor cell origin. At the onset, the DC-MDS was characterized by chromosome seven monosomy and NRAS, RUNX1, and BCOR mutations. Because of a familiar history of colorectal neoplasia and the variant allele frequency (VAF) of NRAS mutation at the onset, this mutation was searched on germline DNA in both the donor and the recipient, but the result was negative. Moreover, after transplant (+4 months), the patient developed severe and long-lasting chronic graft-versus-host disease (cGVHD), requiring multiple lines of treatments. Because of the severe immunosuppression, recurrent infections occurred and, lately, the patient died due to septic shock. Conclusion: This case report highlights the need, whenever possible, to evaluate the donor origin of the posttransplant myelodysplasia and acute leukemias. The potential key role of the impaired immune surveillance and of long-lasting immunosuppression appears to be emerging in the development of this case of DC-MDS. Finally, this case reminds the importance to investigate the familiar genetic predisposition in donors with a familiar history of more...
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- 2020
7. P. aeruginosa bloodstream infections among hematological patients: an old or new question?
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Cattaneo, Chiara, Antoniazzi, F., Casari, S., Ravizzola, G., Gelmi, M., Pagani, C., D’Adda, M., Morello, E., Re, A., Borlenghi, E., Manca, N., and Rossi, G.
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- 2012
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8. Setting the Social Impact monitoring framework for NBS: methodology, drawbacks and measurement case study from Milan
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Mahmoud, I. and Morello, E.
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urban regeneration ,horizon 2020 ,nature-based solutions, urban regeneration, horizon 2020 ,nature-based solutions - Published
- 2021
9. PRINCIPLES GUIDING NBS PERFORMANCE AND IMPACT EVALUATION
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Skodra, J., Connop, S., Tacnet, J. -M., Van Cauwenbergh, N., Almassy, D., Baldacchini, C., Basco Carrera, L., Caitana, B., Cardinali, M., Feliu, E., Garcia, I., Garcia-Blanco, G., Jones, L., Kraus, F., Mahmoud, I., Maia, S., Morello, E., Pérez Lapeña, B., Pinter, L., Porcu, F., Reichborn-Kjennerud, K., Ruangpan, L., Rutzinger, M., and Vojinovic, Z. more...
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sustainable development ,atmospheric pollution , biodiversity , community resilience , database , decision-making , environmental impact , environmental indicator , environmental risk prevention , innovation , natural hazard , sustainable development , urban area , user guide , waste management ,atmospheric pollution ,environmental indicator ,decision-making ,environmental risk prevention ,natural hazard ,environmental impact ,innovation ,community resilience ,user guide ,waste management ,database ,biodiversity ,urban area - Published
- 2021
10. MAPPING URBAN VENTILATION CORRIDORS AND ASSESSING THEIR IMPACT UPON THE COOLING EFFECT OF GREENING SOLUTIONS
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Eldesoky, A. H. M., primary, Colaninno, N., additional, and Morello, E., additional
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- 2020
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11. Older cancer patients in an Italian hospice
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Cacioppo, C, Morello, E, Casiraghi, L, Sandri, R, and Monfardini, S
- Published
- 2009
12. The Green Breath of the City: A Dynamic Approach for Air Purification through NbS in the City of Milan, Italy
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Abbasishekar, M., Mahmoud, I., and Morello, E.
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Air pollution exposure ,Urban green Nature-based solution ,Air purification ,Air purification, Urban green Nature-based solution, Air pollution exposure, Optimal selection, Optimal targeting ,Optimal targeting ,Optimal selection - Published
- 2020
13. Are Nature-based solutions the answer to urban sustainability dilemma? The case of CLEVER Cities CALs within the Milanese urban context
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Mahmoud, I. and Morello, E.
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European policies ,urban sustainability ,shared governance - Published
- 2020
14. Type I autoimmune hepatitis: clinical course and outcome in an Italian multicentre study
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FLOREANI, A., NIRO, G., RIZZOTTO, E. ROSA, ANTONIAZZI, S., FERRARA, F., CARDERI, I., BALDO, V., PREMOLI, A., OLIVERO, F., MORELLO, E., and DURAZZO, M.
- Published
- 2006
15. A Case of Relapsed Meningeal Burkitt’s Leukemia/ Lymphoma Treated With Intraventricular Rituximab Combined With High-Dose Cytarabine
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Billio, A., Svaldi, M., Morello, E., Amato, B., and Coser, P.
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- 2006
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16. Energy efficiency and occupants’ behavior: analysis of a public housing case study
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Sangalli, A., Pagliano, L., Causone, F., Salvia, G., and Morello, E.
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energy savings ,indoor air climate monitoring ,energy savings, energy refurbishment, indoor air climate monitoring ,energy refurbishment - Published
- 2019
17. Sustainability designed with(out) people? Understanding for what energy is (over-)consumed by tenants in an energy efficient public housing in Milan
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Salvia, G., Rotondo, Federica, Morello, E., Sangalli, A., Pagliano, L., and Causone, F.
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case study ,public housing ,design for sustainable consumption ,energy use - Published
- 2019
18. Integrating NBS in cities through co-creation: a practical guidance for CLEVER Cities
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Mahmoud, I., Morello, E., and Salvia, G.
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CLEVER CITIES ,Nature-based Solutions - Published
- 2019
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19. Biological versus Clinical Risk Factors in Acute Myeloid Leukemia: Is There a Winner?
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Malagola, M., Polverelli, N., Cancelli, V., Morello, E., Turra, A., Borlenghi, E., Cattina, F., Rambaldi, B., Bernardi, S., Zanaglio, C., Dereli Eke, Elif, Gandolfi, L., Farina, M., and Russo, D.
- Subjects
Article Subject ,hemic and lymphatic diseases - Abstract
We present a case of a patient with a three-month history of peripheral blood cytopenia without a confirmed diagnosis of myelodysplastic syndrome, who developed a favourable-risk acute myeloid leukemia (AML), according to the European Leukemia Net (ELN) criteria. The patient achieved a complete remission with incomplete platelet recovery (CRi) after induction. The patient achieved the morphological CR after the first consolidation and completed the first-line treatment with a syngeneic stem cell transplantation (SCT). A disease relapse occurred after one year of CR (blast cell count in the bone marrow 15%), and the patient was offered a haplo-SCT, which he refused due to personal reasons. In this paper, we discuss the interplay between clinical and biological risk factors in non-high-risk AML patients and speculate that some old clinical risk factors (e.g., age of the patient, achievement of CR after induction, and previous history of myelodysplastic syndrome) may still impact on the treatment decision algorithm of some of these patients. more...
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- 2019
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20. Mobility management at Politecnico di Milano: New infrastructures and behavioural change
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Messori, G, primary, Morello, E, additional, Perotto, E, additional, Infussi, F, additional, Mondini, G, additional, Faroldi, E, additional, Tolentino, S, additional, and Ugolini, M, additional
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- 2019
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21. PB2269 PARENTERAL NUTRITION AND ACUTE GVHD IN HEMATOPOIETIC STEM CELLS TRANSPLANTATION: A PROSPECTIVE OBSERVATIONAL COHORT STUDY
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Arena, F., primary, Morello, E., additional, Bertocchi, G., additional, Malagola, M., additional, Samarani, E., additional, Bertulli, A., additional, Farina, M., additional, Gandolfi, L., additional, Polverelli, N., additional, Turra, A., additional, Cattina, F., additional, Andreoli, M., additional, and Russo, D., additional more...
- Published
- 2019
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22. PS1540 MULTIPARAMETRIC PREDICTIVE SCORE FOR GRAFT VERSUS HOST DISEASE (GVHD) IN PATIENTS SUBMITTED TO ALLOGENEIC STEM CELLS TRANSPLANTATION (SCT)
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Turra, A., primary, Polverelli, N., additional, Corvini, F., additional, Morello, E., additional, Malagola, M., additional, Arena, F., additional, Andreoli, M., additional, Bertulli, A., additional, Farina, M., additional, Cattina, F., additional, Rambaldi, B., additional, Gandolfi, L., additional, Zollner, T., additional, Buttini, E. Accorsi, additional, Bernardi, S., additional, Zanaglio, C., additional, Foroni, C., additional, Re, F., additional, and Russo, D., additional more...
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- 2019
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23. PF404 TUMOR-DERIVED EXOSOMES MAY BE USED AS NEW INFORMATIVE TOOL FOR THE DETECTION OF BONE MARROW RESIDUAL CML LEUKEMIC CELLS ACTIVITY
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Bernardi, S., primary, Foroni, C., additional, Zanaglio, C., additional, Re, F., additional, Polverelli, N., additional, Turra, A., additional, Morello, E., additional, Farina, M., additional, Cattina, F., additional, Gandolfi, L., additional, Zollner, T., additional, Accorsi Buttini, E., additional, Malagola, M., additional, and Russo, D., additional more...
- Published
- 2019
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24. Ondate di calore e resilienza urbana : una proposta metodologica per la valutazione della vulnerabilità della Città Metropolitana di Milano per ciascuna sezione di censimento Istat
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Maragno, D., Ruzzante, F., Morello, E., Colaninno, Nicola, and Musco, F.
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morfologia urbana ,ondate di calore ,climate change ,ondate di calore, isola di calore urbana, vulnerabilità, adattamento, cambiamenti climatici, resilienza, morfologia urbana ,isola di calore urbana ,adattamento ,resilienza ,climate change, adaptation ,adaptation ,vulnerabilità ,cambiamenti climatici - Published
- 2018
25. Design tips and checklist
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Morello, E. and Butera, F.
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sustainable development ,Africa, sustainable development, urban design, urban design checklist, Tropical Africa, sustainable urban design ,Africa ,urban design checklist ,Tropical Africa ,sustainable urban design ,urban design - Published
- 2018
26. A Case of Spondyloarthritis in Patient Affected by Unicentric Castleman’s Disease Effectively Managed with Surgery Resection and Tocilizumab Treatment
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Filippini, M., Cartella, S., Bonzanini, O., Morello, E., and Tincani, A.
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Article Subject - Abstract
A 38-year-old woman was referred to our hospital for rheumatologic manifestations (migrant arthritis and tenosynovitis), without psoriasis or family history of psoriasis, gastroenteric manifestations, or recent genitourinary infections. The instrumental and laboratory tests have suggested a diagnosis of undifferentiated seronegative HLA-B27-positive spondyloarthritis with predominantly peripheral involvement. The symptoms were very severe and resistant to anti-inflammatory drugs and steroids. She had a history of hyaline-vascular unicentric Castleman’s disease (HBV, HIV, and HHV-8 negative) treated with surgery resection. After a first pharmacological attempt with sulfasalazine (suspended for urticarial rash), we managed the patient with monotherapy tocilizumab 8 mg/kg, with full response of rheumatologic manifestations. The efficacy of tocilizumab was confirmed even after a follow-up of three years. Our experience seems to describe a new late-onset autoimmune disease (only 21 cases described in literature) potentially related to Castleman’s disease. The patient experienced marked improvement from IL-6-based therapy (tocilizumab). more...
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- 2018
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27. I dati satellitari per l’analisi del fenomeno isola di calore urbano e la valutazione di misure di mitigazione: il caso della Città di Milano
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Colaninno, N., Morello, E., Musco, F., and Maragno, D.
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dati satellitari ,dati satellitari, remote sensing, adattamento, isola di calore, NDVI, microclima urbano, telerilevamento, rinverdimento ,remote sensing ,rinverdimento ,NDVI ,adattamento ,telerilevamento ,microclima urbano ,isola di calore - Published
- 2018
28. Co-Creation Pathway as a catalyst for implementing Nature-based Solution in Urban Regeneration Strategies Learning from CLEVER Cities framework and Milano as test-bed
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Mahmoud, I. and Morello, E.
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Urban Innovation Partnership ,CLEVER Action Labs ,co-creation ,CLEVER Cities ,nature-based solutions - Published
- 2018
29. Milano Città Metropolitana Resiliente : un percorso operativo a supporto della redazione del futuro Piano Territoriale Metropolitano
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Magni, F., Colaninno, N., Maragno, D., Morello, E., Musco, F., and Caserini, S.
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città metropolitana ,pianificazione climatica ,adattamento ,resilienza ,adattamento, città metropolitana, resilienza, pianificazione climatica, vulnerabilità ,vulnerabilità - Published
- 2018
30. Minimise energy demand for transport through urban design
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Morello, E. and Butera, F.
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sustainable development ,Africa ,transport ,energy efficiency, Africa, sustainable development, transport, urban design ,urban design ,energy efficiency - Published
- 2018
31. Towards an Eco-City Future: A Renewable Energy Supply and Smart Mobility Symbiosis
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Olivia Zara, Morello, E., and Gomes, V.
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Energy Urban Planning ,Urban Metabolism ,Solar Energy ,Distributed generation ,Urban Metabolism, Energy Urban Planning, Solar Energy, Distributed generation, Smart Mobility ,Smart Mobility - Published
- 2017
32. Hypoxia up-regulates SERPINB3 through HIF-2α in human liver cancer cells
- Author
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Cannito, S, Turato, C, Paternostro, C, Biasiolo, A, Colombatto, S, Cambieri, I, Quarta, S, Novo, E, Morello, E, Villano, G, Fasolato, S, Musso, T, David, E, Tusa, Ignazia, Rovida, Elisabetta, Autelli, R, Smedile, A, Cillo, U, Pontisso, P, and Parola, M. more...
- Subjects
serpinB ,hypoxia ,Hepatocellular carcinoma ,hypoxia inducible factor (HIF) ,reactive oxigen species (ROS) - Published
- 2015
33. Scientific, Technical and Economic Committee for Fisheries. Mediterranean Fisheries Assessments Part 2 (STECF-14-19)
- Author
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Cardinale, M. (Massimiliano), Abella, J.A. (J. Alvaro), Martín, P. (Paloma), Scarcella, G. (Giuseppe), Bitetto, I. (Isabella), Carpi, P. (Piera), Colloca, F. (Francesco), Guijarro, B. (Beatriz), Mannini, A. (Alessandro), Maynou, F. (Francesc), Morello, E. (Elisabetta), Murenu, M. (Matteo), Orio, A. (Alessandro), Pengal, P. (Polona), Pérez-Gil, J.L. (José Luis), Quetglas, A. (Antoni), Recasens, L. (Laura), Saraux, C. (Claire), Sbrana, M. (Mario), and Torres-Cutillas, P. (Pedro) more...
- Subjects
Centro Oceanográfico de Baleares ,Pesquerías - Abstract
The STECF expert working group "EWG 1419 - Mediterranean assessment part 2", has convened in Rome during 19-23 January 2015 and addressed a series of issues as requested by DG MARE in the correspomnding terms of references. The detailed output of this working group efforts is included in the following report. The report was reviewed by the STECF spring plenary during 13-17 April 2015 more...
- Published
- 2015
34. Imatinib mesylate in the treatment of Core Binding Factor leukemias with KIT mutations. A report of three cases
- Author
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Cairoli, R, Beghini, A, Morello, E, Grillo, G, Montillo, M, Larizza, L, Morra, E, Cairoli R, Beghini A, Morello E, Grillo G, Montillo M, Larizza L, Morra E, Cairoli, R, Beghini, A, Morello, E, Grillo, G, Montillo, M, Larizza, L, Morra, E, Cairoli R, Beghini A, Morello E, Grillo G, Montillo M, Larizza L, and Morra E more...
- Abstract
Aim of this study is to investigate the capability of Imatinib to induce an anti-leukemic effect in Core Binding Factor (CBF)-leukemia patients presenting either with extracellular juxtamembrane or kinase KIT mutations. On the basis of a screening analysis for KIT mutations, two patients with a kinase mutation and one with extracellular juxtamembrane mutation, in first or subsequent leukemic relapse, received 400 mg Imatinib twice daily for 30 days. After Imatinib discontinuation, bone marrow cells were re-tested to assess the KIT mutational status and the chromosomal set. In our experience, none of the treated patients had a response by standard criteria; in particular, we did not observe any activity against acute myeloid leukemia (AML) associated with KIT kinase mutations. However, in the patient with extracellular juxtamembrane mutation, Imatinib seems to have some clinical beneficial effect and, most important, is able to abrogate the leukemic subclone carrying the mutation. Whether Imatinib, in combination with other agents, may play a role in the treatment of AML with more sensitive extracellular juxtamembrane KIT mutation remains to be determined. more...
- Published
- 2005
35. Stygofauna enhance prokaryotic transport in groundwater ecosystems
- Author
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Smith, R.J., Paterson, J.S., Launer, E., Tobe, S.S., Morello, E., Leijs, R., Marri, S., Mitchell, J.G., Smith, R.J., Paterson, J.S., Launer, E., Tobe, S.S., Morello, E., Leijs, R., Marri, S., and Mitchell, J.G. more...
- Abstract
More than 97% of the world’s freshwater reserves are found in aquifers, making groundwater one of the most important resources on the planet. Prokaryotic communities in groundwater underpin the turnover of energy and matter while also maintaining groundwater purity. Thus, knowledge of microbial transport in the subsurface is crucial for maintaining groundwater health. Here, we describe for the first time the importance of stygofauna as vectors for prokaryotes. The “hitch-hiking” prokaryotes associated with stygofauna may be up to 5 orders of magnitude higher in abundance and transported up to 34× faster than bulk groundwater flow. We also demonstrate that prokaryotic diversity associated with stygofauna may be higher than that of the surrounding groundwater. Stygofauna are a newly recognized prokaryotic niche in groundwater ecosystems that have the potential to transport remediating, water purifying and pathogenic prokaryotes. Therefore, stygofauna may influence ecosystem dynamics and health at a microbial level, and at a larger scale could be a new source of prokaryotic diversity in groundwater ecosystems. more...
- Published
- 2016
36. French Intensive Care Society, International congress - Réanimation 2016
- Author
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Jaillette, E, Girault, C, Brunin, G, Zerimech, F, Chiche, A, Broucqsault Dedrie, C, Fayolle, C, Minacori, F, Alves, I, Barrailler, S, Robriquet, L, Delaporte, E, Thellier, D, Delcourte, C, Duhamel, A, Nseir, S, Valette, X, Desmeulles, I, Savary, B, Masson, R, Seguin, A, Daubin, C, Sauneuf, B, Verrier, P, Pottier, V, Orabona, M, Samba, D, Viquesnel, G, Lermuzeaux, M, Hazera, P, Hanouz, J, Parienti, J, Du Cheyron, D, Demoule, A, Clavel, M, Rolland Debord, C, Perbet, S, Terzi, N, Kouatchet, A, Wallet, F, Roze, H, Vargas, F, Guérin, C, Dellamonica, J, Jaber, S, Similowski, T, Quenot, J, Binquet, C, Vinsonneau, C, Barbar, S, Vinault, S, Deckert, V, Lemaire, S, Hssain, A, Bruyère, R, Souweine, B, Lagrost, L, Adrie, C, Jung, B, Daurat, A, De Jong, A, Chanques, G, Mahul, M, Monnin, M, Molinari, N, Lheureux, O, Trepo, E, Hites, M, Cotton, F, Wolff, F, Surin, R, Créteur, J, Vincent, J, Gustot, T, Jacobs, F, Taccone, F, Neuville, M, Timsit, J, El Helali, N, Le Monnier, A, Magalhaes, E, Radjou, A, Smonig, R, Soubirou, J, Voiriot, G, Sonneville, R, Bouadma, L, Mourvillier, B, Gélisse, E, Brasseur, A, Roisin, S, De Backer, D, Van Ruychevelt, V, Carlier, E, Piagnerelli, M, Vanhaeverbeek, M, Danguy, C, Biston, P, Au, S, Begot, E, Dalmay, F, Repessé, X, Prat, G, Bouferrache, K, Slama, M, Vieillard Baron, A, Monnet, X, Marik, P, Teboul, J, Jozwiak, M, Richard, C, Chauvet, J, El Dash, S, Delastre, O, Bouffandeau, B, Jusserand, D, Michot, J, Bauer, F, Brazier, F, Mercado, P, Kontar, L, Titeca, D, De Cagny, B, Bacari Risal, G, Riviere, A, Maizel, J, Guillot, C, Le Reun, C, Lampin, M, Sadik, A, Botte, A, Leteurtre, S, Collins, A, Kempeneers, C, Cajgfinger, N, Ohlmann, C, Pouyau, R, Subtil, F, Baudin, F, Massenavette, B, Javouhey, E, Milesi, C, Essouri, S, Liet, J, Afanetti, M, Durand, S, Durand, P, Roze, J, Dupont, D, Cambonie, G, Soyer, B, Rusca, M, Lukaszewicz, A, Crassard, I, Guichard, J, Bresson, D, de la Garanderie, D, Cantier, M, Sabben, C, Louedec, L, Delbosc, S, Journé, C, Ou, P, Klein, I, Chau, F, Lefort, A, Desilles, J, Michel, J, Mazighi, M, Salem, O, Demeret, S, Bolgert, F, Sharshar, T, Grabli, D, Arib, S, Crippa, I, Soummer, A, Engrand, N, Guedin, P, Aldea, S, Cerf, C, Desailly, V, Pasquier, P, Brun, P, Roux, D, Latournerie, G, Kasprzyk, L, Grosjean, V, Latreche, A, Habert, P, Huot, S, Jobin, T, Tesnière, A, Dreyfuss, D, Ricard, J, Mignon, A, Gaudry, S, Laithier, F, Kimmoun, A, Chouihed, T, Albizzati, S, Camenzind, E, Vanhuyse, F, Levy, B, Cour, M, Venet, F, Hernu, R, Demaret, J, Monneret, G, Argaud, L, Dumas, F, Lamhaut, L, Rosencher, J, Pène, F, Varenne, O, Carli, P, Jouven, X, Spaulding, C, Cariou, A, Geri, G, Bonnetain, F, Marijon, E, Empana, J, Mirouse, A, Resche Rigon, M, Mayaux, J, Rabbat, A, Meert, A, Benoit, D, Bruneel, F, Azoulay, E, Dupuis, C, Schwebel, C, Ruckly, S, Goldgran Toledano, D, Marcotte, G, Lafarge, A, Pichereau, C, Theodose, I, Scotto, M, Kemlin, D, Ghrenassia, E, Schlemmer, B, Vimpere, D, Galicier, L, Contou, D, Guérot, E, Grimaldi, 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Elkhawand, C, Vermeesh, F, Vermeesh, F., and CITERIO, GIUSEPPE more...
- Abstract
Determinants of outcome in critically ill patients with hematological malignancy and central neurological failure: data from the TRIAL OH study
- Published
- 2016
37. Human Anti Cancer Cytokine Induced Killer Cells and TheirInteraction With the Host Immune System
- Author
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Coin, S, Cavattoni, I, Morello, E, Laudanna, Carlo, Montresor, Alessio, Pievani, A, Bronte, Vincenzo, Cortelazzo, S, Rambaldi, A, Introna, M, and Monsurro', Vladia
- Subjects
adoptive therapy - Published
- 2011
38. Allogeneic transplantation improves the overall and progression free-survival of Hodgkin's lymphoma patients relapsing after autologuos transplantation: a GITMO retrospective study based on time of HLA typing and donor availability
- Author
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Sarina, B, Castagna, L, Farina, F, Patriarca, F, Benedetti, Fabio, Carella, Am, Falda, M, Guidi, S, Ciceri, F, Bonini, A, Ferrari, S, Malagola, M, Morello, E, Milone, G, Bruno, B, Mordini, N, Viviani, S, Levis, A, Giordano, L, Santoro, A, and Corradini, P. more...
- Subjects
ALLOGENEIC BONE MARROW ,TRANSPLANT ,RELAPSE - Published
- 2010
39. QuantiFERON®-CMV for immune- monitoring in patientes undergoing allogeneic Hematopoietic stem cell transplantation
- Author
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Morello, E, Pagani, E, Monsurro', Vladia, Cavattoni, Im, Coin, S, Larcher, C, Tridente, G, and Cortellazzo, S.
- Subjects
CMV ,IFN ,transplantation - Published
- 2008
40. IFN-gamma induced by PHA stimulation as new marker for GVHD prection in patientes undergoing allogeneic hematopoietic stem cell transplantation
- Author
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Morello, E, Pagani, E, Monsurro', Vladia, Cavattoni, Im, Coin, S, Larcher, C, Tridente, G, and Cortellazzo, S.
- Subjects
IFN gamma ,PHA ,GVHD - Published
- 2008
41. QuantiFERON®-CMV for immune-monitoring after allogeneic stem cell transplastation (alloSCT): preliminary data
- Author
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Morello, E, Pagani, E, Monsurro', Vladia, Cavattoni, Im, Casini, M, Larcher, C, Tridente, G, and Cortellazzo, S.
- Subjects
CMV ,transplantation ,IFN - Published
- 2008
42. Nonmyeloablative allogeneic stem cell transplantation in elderly patients with hematological malignancies: results from the GITMO (Gruppo Italiano Trapianto Midollo Osseo) multicenter prospective clinical trial
- Author
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Falda, M, Busca, A, Baldi, Ileana, Mordini, N, Bruno, B, Allione, B, Rambaldi, A, Morello, E, Narni, F, Santarone, S, Locatelli, F, Bacigalupo, A, and Gruppo Italiano Trapianto Midollo Osseo
- Subjects
Male ,Reoperation ,medicine.medical_specialty ,Transplantation Conditioning ,medicine.medical_treatment ,Graft vs Host Disease ,Hematopoietic stem cell transplantation ,Gastroenterology ,Disease-Free Survival ,Postoperative Complications ,Internal medicine ,Nonmyeloablative ,allogeneic ,stem cell transplantation ,elderly patients ,medicine ,Humans ,Transplantation, Homologous ,Prospective Studies ,Prospective cohort study ,Survival rate ,Aged ,business.industry ,Incidence (epidemiology) ,Siblings ,Graft Survival ,Hematopoietic Stem Cell Transplantation ,Hematology ,Middle Aged ,Tissue Donors ,Fludarabine ,Surgery ,Transplantation ,Survival Rate ,Regimen ,Hematologic Neoplasms ,Female ,business ,Vidarabine ,Whole-Body Irradiation ,medicine.drug ,Agranulocytosis - Abstract
This study aimed to evaluate the efficacy of a nonmyeloablative conditioning consisting of fludarabine and TBI in patients aged > or =60 years.A total of 32 patients (median age 62 years; range 60-70) with hematological malignancies were treated with fludarabine (30 mg/m(2) x 3-5 days) and 200 cCy TBI followed by allogeneic hematopoietic stem cell transplantation (HSCT) from a matched-sibling donor. GVHD prophylaxis consisted of cyclosporine and mycophenolate. Neutrophil recovery occurred in all patients at a median time of 16 days (range 9-34). Six patients did not become granulocytopenic. On day +30, 10 patients had >95% donor chimerism and 19 patients had mixed chimerism. The cumulative probabilities of Grade II-IV acute GVHD and chronic GVHD were 48 and 83%, respectively. Transplant-related mortality at 100 days and 1 year was 6 and 10%, respectively. The probabilities of 2-year overall (OS) and progression-free survival (PFS) were 39 and 35%, respectively. The estimated 2-year probability of OS and PFS for patients in early disease stages were 77 and 64%, respectively, which were significantly higher than the survival and PFS estimates of 0% obtained in patients with advanced disease stages at the time of transplant. Our analysis would suggest that for patients older than 60, this regimen is well tolerated and associated with a low incidence of transplant-related mortality. The leukemic burden at time of transplant has proven to be the most important risk factor for the outcome. more...
- Published
- 2007
43. Studio dell'ipossia e anossia nell'Adriatico settentrionale nell'ambito dei progetti ANOCSIA (MUR-Firb) ed EMMA (UE-LIFE) e le fasi sperimentali realizzate
- Author
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Ravaioli M., Alvisi F., Focaccia P., Catalano G., Cozzi S., Cantoni C., Luchetta A., Arneri E., Morello E., Negri A., Russo A., Iermano I., Falco P., Morigi C., Serratore P., Trentini M., Ferrari C.R., Tarlazzi S., Prevedelli D., Simonini R., Matteucci G., Bajt O., Benedettini M., and Favi E. more...
- Subjects
anossia ,sistemi integrati ,boa multiparametrica ,strategie di gestione ,ipossia ,crociere oceanografiche ,eutrofia ,modello di previsione ,risorse demersali ,Adriatico Settentrionale - Abstract
In Adriatico settentrionale i casi di ipossia/anossia, dei fondali sono fenomeni noti da secoli, come in molti bacini parzialmente chiusi e poco profondi, soggetti a stratificazione estiva delle acque dove, episodi straordinari, anche naturali, di emissione di sostanze nutrienti possono indurre, in caso di adatte situazioni meteo-marine del bacino, fioriture algali imponenti. Queste, depositandosi sul fondo consumano l'ossigeno disciolto inducendo situazioni di ipossia/anossia più o meno pronunciate e con scale spazio-temporali più o meno estese. Oltre all'importanza ambientale "per sé", i fenomeni ipossici/anossici hanno un forte impatto sull'economia delle regioni interessate. Nel nord Adriatico la regione Emilia-Romagna e' quella che più ne risente per gli aspetti riguardanti la qualità dell'ambiente costiero, la quantità e qualità del pescato, il presidio sanitario delle zone adibite alla balneazione, dei prodotti ittici e della maricultura. Lo studio di questi fenomeni è stato approfondito all'interno del progetto ANOCSIA (2004-2007) -MUR-FIRB: L'aumento della frequenza degli eventi critici negli ultimi anni è stata spiegata in termini di variazioni sia climatiche che di carico eutrofico di origine antropica. L'individuazione dei meccanismi di innesco di tali fenomeni, di origine naturale o di origine antropica, è tuttavia di fondamentale importanza rispetto alla possibilità di mettere in atto azioni di prevenzione e mitigazione dei fenomeni stessi. Per questo la fenomenologia delle ipossie è stata oggetto di studio diretto o indiretto di vari progetti di ricerca: Rispetto a questi progetti a prevalente obiettivo scientifico-conoscitivo, il progetto EMMA(2004-2007-http://emma.bo.ismar.cnr.it), approvato nel settore LIFE-Environment dell'Unione Europea, comprendente nell'area di studio la parte slovena della costa dell'Istria, presenta in aggiunta una parte applicativo-gestionale. In questo, EMMA, partendo dalle conoscenza acquisite, si propone di: 1) fare crescere la consapevolezza sulla necessità di utilizzo di sistemi integrati osservazionali-modellistici-previsionali di gestione ambientale presso gli enti deputati all'amministrazione del territorio, 2) trasferire le conoscenze scientifiche e tecnologiche alle pubbliche amministrazioni e agli attori socioeconomici al fine di porre in essere misure ed interventi concertati in grado di contrastare le cause del degrado dell'ecosistema marino e mitigarne gli impatti. A tal fine EMMA punta a creare/proporre: i)- un sito sperimentale per lo studio delle anossie ad integrazione della rete di monitoraggio del Nord Adriatico; ii) un modello uni-dimensionale semplificato di previsione a 72 ore della concentrazione dell'O2; iii) una lista dei possibili indicatori di condizioni anossiche basata sul comportamento specifico di alcune specie oggetto di pesca; iv) strategie di gestione delle risorse ittiche basate sulla conoscenza della distribuzione delle risorse di pesca pelagiche e demersali e sull'analisi delle aree e degli strumenti di pesca tradizionali e del comportamento della flotta commerciale; v) un protocollo eco-tossicologico che includa assieme batteri marini autoctoni, biotossine, pellets fecali e inquinamento chimico; vi) strategie di intervento a breve termine, che prevedano norme temporanee per la gestione di eventi anossici in atto, basate sul sistema integrato di monitoraggio, previsione e DSS; vii) strategie di intervento a lungo termine, da integrare con gli strumenti pubblici di gestione e pianificazione che prevedano misure concrete per la prevenzione e la riduzione dell'impatto negativo delle anossie nell'area di interesse Di queste, le azione poste in essere al momento attuale sono state: una crociera oceanografica ANEMRE sulla N/O Urania del CNR, l'individuazione del sito sperimentale per lo studio delle anossie e la posa della boa per l'osservazione automatica (http://e1.bo.ismar.cnr.it) l'implementazione del modello di previsione della concentrazione dell'O2 nella zona costiera romagnola. more...
- Published
- 2006
44. Prevalence of helicobacter pylori cag-a positive strains infection in non-alcoholic steatohepatitis
- Author
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Durazzo, Marilena, Musso, G., Pellicano, R., Premoli, A., Fagà, E., Morello, E., Biroli, G., Rabbione, L., Gambino, Roberto, Cassader, Maurizio, and Pagano, Gian Franco
- Published
- 2003
45. A high dietary saturated fat is associated with insulin resistance in non-alcoholic steatohepatitis
- Author
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Musso, G., Durazzo, Marilena, DE MICHIELI, Franco, Gambino, Roberto, Cassader, Maurizio, Fagà, E., Morello, E., Biroli, G., and Pagano, Gian Franco
- Published
- 2003
46. Annexin II incorporated into influenza virus particles supports virus replication by converting plasminogen into plasmin
- Author
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LeBouder, F. (Fanny), Morello, E. (Eric), Rimmelzwaan, G.F. (Guus), Bosse, F. (Françoise), Péchoux, C. (Christine), Delmas, B. (Bernard), Riteau, B. (Béatrice), LeBouder, F. (Fanny), Morello, E. (Eric), Rimmelzwaan, G.F. (Guus), Bosse, F. (Françoise), Péchoux, C. (Christine), Delmas, B. (Bernard), and Riteau, B. (Béatrice) more...
- Abstract
For influenza viruses to become infectious, the proteolytic cleavage of hemagglutinin (HA) is essential. This usually is mediated by trypsin-like proteases in the respiratory tract. The binding of plasminogen to influenza virus A/WSN/33 leads to the cleavage of HA, a feature determining its pathogenicity and neurotropism in mice. Here, we demonstrate that plasminogen also promotes the replication of other influenza virus strains. The inhibition of the conversion of plasminogen into plasmin blocked influenza virus replication. Evidence is provided that the activation of plasminogen is mediated by the host cellular protein annexin II, which is incorporated into the virus particles. Indeed, the inhibition of plasminogen binding to annexin II by using a competitive inhibitor inhibits plasminogen activation into plasmin. Collectively, these results indicate that the annexin II-mediated activation of plasminogen supports the replication of influenza viruses, which may contribute to their pathogenicity. Copyright more...
- Published
- 2008
- Full Text
- View/download PDF
47. Inactivation of the ybdD Gene in Lactococcus lactis Increases the Amounts of Exported Proteins
- Author
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Morello, E., primary, Nouaille, S., additional, Cortes-Perez, N. G., additional, Blugeon, S., additional, Medina, L. F. C., additional, Azevedo, V., additional, Gratadoux, J. J., additional, Berm�dez-Humar�n, L. G., additional, Le Loir, Y., additional, and Langella, P., additional more...
- Published
- 2012
- Full Text
- View/download PDF
48. Expression of Ki67, BCL-2, and COX-2 in Canine Cutaneous Mast Cell Tumors
- Author
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Vascellari, M., primary, Giantin, M., additional, Capello, K., additional, Carminato, A., additional, Morello, E. M., additional, Vercelli, A., additional, Granato, A., additional, Buracco, P., additional, Dacasto, M., additional, and Mutinelli, F., additional more...
- Published
- 2012
- Full Text
- View/download PDF
49. Target IRTE architectures - Theory and Practice of the 5T architectural design
- Author
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Mauro, Vito, Morello, E., and Wrathall, C.
- Published
- 1993
50. Complementation of the Lactococcus lactis Secretion Machinery with Bacillus subtilis SecDF Improves Secretion of Staphylococcal Nuclease
- Author
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Nouaille, S., primary, Morello, E., additional, Cortez-Peres, N., additional, Le Loir, Y., additional, Commissaire, J., additional, Gratadoux, J. J., additional, Poumerol, E., additional, Gruss, A., additional, and Langella, P., additional more...
- Published
- 2006
- Full Text
- View/download PDF
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