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2. Highly efficient organic light-emitting diodes from delayed fluorescence

Author

Uoyama, Hiroki, Goushi, Kenichi, Shizu, Katsuyuki, Nomura, Hiroko, and Adachi, Chihaya

Subjects
Organic LEDs -- Structure, Semiconductors -- Innovations, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

The inherent flexibility afforded by molecular design has accelerated the development of a wide variety of organic semiconductors over the past two decades. In particular, great advances have been made [...]

Published
2012
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3. Additional file 1 of The validity of the claims-based definition of rheumatoid arthritis evaluated in 64 hospitals in Japan

Author

Kubota, Kiyoshi, Yoshizawa, Masaki, Takahashi, Satoru, Fujimura, Yoshiaki, Nomura, Hiroko, and Kohsaka, Hitoshi

Abstract

Additional file 1 Appendix 1 Pilot study and PDF survey form. Appendix 2 Table S2: Original population and random samples selected from the original population who had inpatient or outpatient medical care in the study hospital at least once between February 1, 2018 and January 31, 2019. Appendix 3 Table S3: The number of patients of true positive (TP), false negative (FN), false positive (FP), and true negative (TN) and the sensitivity (SE), specificity (SP), positive predictive value (PPV) and negative predictive value (NPV), and the prevalence of the definition-positive patients for 32 claims-based definitions for RA when 39 patients with rheumatoid arthritis (RA) treated in a different hospital were included in the study population. Appendix 4: Sensitivity analysis to evaluate the effect of potential misclassification of patients with rheumatoid arthritis (RA) who did not meet “Definitions of possible cases of RA” (Table 1) as patients having no RA on the prevalence of definition–positive patients and the adjusted prevalence.

Published
2021
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7. Evidence and mechanism of efficient thermally activated delayed fluorescence promoted by delocalized excited states

Author

Hosokai, Takuya, Matsuzaki, Hiroyuki, Nakanotani, Hajime, Tokumaru, Katsumi, Tsutsui, Tetsuo, Furube, Akihiro, Nasu, Keirou, Nomura, Hiroko, Yahiro, Masayuki, Adachi, Chihaya, Hosokai, Takuya, Matsuzaki, Hiroyuki, Nakanotani, Hajime, Tokumaru, Katsumi, Tsutsui, Tetsuo, Furube, Akihiro, Nasu, Keirou, Nomura, Hiroko, Yahiro, Masayuki, and Adachi, Chihaya

Abstract

The design of organic compounds with nearly no gap between the first excited singlet (S1) and triplet (T1) states has been demonstrated to result in an efficient spin-flip transition from the T1 to S1 state, that is, reverse intersystem crossing (RISC), and facilitate light emission as thermally activated delayed fluorescence (TADF). However, many TADF molecules have shown that a relatively appreciable energy difference between the S1 and T1 states (~0.2 eV) could also result in a high RISC rate. We revealed from a comprehensive study of optical properties of TADF molecules that the formation of delocalized states is the key to efficient RISC and identified a chemical template for these materials. In addition, simple structural confinement further enhances RISC by suppressing structural relaxation in the triplet states. Our findings aid in designing advanced organic molecules with a high rate of RISC and, thus, achieving the maximum theoretical electroluminescence efficiency in organic light-emitting diodes.

Published
2017

10. Working Group Report of Rodent Space Experiments in Fy2010

Author

Yamasaki, Masao, Ohira, Yoshinobu, Okuno, Makoto, Ishihara, Akihiko, Shimizu, Tsuyoshi, Kumei, Yasuhiro, Ito, Yasuhiro, Nomura, Hiroko, Takabayashi, Akira, Onishi, Takeo, Katahira, Kiyoaki, Yano, Shoki, Nakano, Tamotsu, and Yamashita, Masamichi

Subjects
space medicine, rat, long-term exposure to microgravity, mouse, rodent module
Abstract

第27回宇宙利用シンポジウム (2011年1月24日-25日, 宇宙航空研究開発機構宇宙科学研究所相模原キャンパス), 相模原市, 神奈川県, The Twenty-seventh Space Utilization Symposium (January 24-25, 2011. Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)(ISAS)), Sagamihara, Kanagawa Japan, To discuss the necessity of space studies in mammal and to seek opportunities of the joint space missions for the animal experiments, we have organized the group for rodent studies with the joint members, which consist of the investigators familiar with the space experiment, in several working groups. We collaborated in the ground-based research using mice and held the joint meetings in 2010. These mice experiment was based on the tissue sharing program in space-utilizing experiment using the mouse drawer system organized by Italian Space Agency (2009), the key person is Dr. Ohira Y and colleagues, and he worked actively among the scientists in Japan and foreign country to maintain the scientific researches and the international collaboration without adequate government supports. From these activities, we cannot persuade ourselves that Japan Space Agency is in earnest for space utilization researches using rodents in the international space station (ISS), and it is thought that we will see to its opportunity ourselves ISS and/or small payload. However, we must require continuously JAXA to organize the project of rodent module in ISS, even if there are no chances to house the mice and rats in outer space. Other key rodent experiment is the investigation under less gravity environment such as the surface of Moon and Mars (Kumei Y). The human will arrive at Mars before next century, thus we also consider the conditions in mammal under the less gravity and more long-term stay in outer space including travel. At the present time, the crews on orbit of ISS are performing the many researches about space medicine in their bodies, and these investigations will produce the important knowledge regarding an exposure to long-duration microgravity and specific environments of the module in the near future. Probably, the new questions will be understood by these results, and the rodents investigations based on the human studies should be needed. Thus, we should perform continuously the ground-based experiments using rodents to lead young scientists interested in the space life science and medicine for next decade., 著者人数: 14人, Number of authors: 14, 資料番号: AA0065129046

Published
2011

11. 呼吸による心臓迷走神経反射の生後発達と重力

Author

Nagaoka, Shunji, Nomura, Hiroko, Hata, Tadayoshi, 長岡 俊治, 野村 裕子, 畑 忠善, Nagaoka, Shunji, Nomura, Hiroko, Hata, Tadayoshi, 長岡 俊治, 野村 裕子, and 畑 忠善

Abstract

One of the origin of the heart rate variability known as a cardiopulmonary reflex is induced by respirations which activate afferent vagal nerve from lung to modulate heart rate through efferent vagal fibers at the sinus node. However the functional developments of such cardiopulmonary reflex is still not well understood. It was recently found that a frequency component of the heart rate variability linked to the respiration in the immature low-birth-weight neonates strongly depend on the postnatal period. The frequency components of the heart rate variability in human neonates, rats and amphibians were analyzed and compared during the developments. Frequency analysis with autocorrelation-FFT method was applied to the heart rate and respiration waves to calculate the respiration-linked component in the power spectra. The comparative analysis of the cardiopulmonary reflex using human and rat neonates resulted in a similar developmental status. In case of human immature neonate, respiration-linked frequency component in the heart rate variability was negligible at day-old 0 and significantly increased at postnatal 1 month. The rat neonate also showed no or negligible respiration linked response until days 8 and it became significant approximately postnatal 1 month. However the amphibian (Rana catesbeiana) indicated no clear response in the entire developmental stages even in adult. The results suggested that the gravity may play an important role to facilitate the cardiopulmonary reflex.

Published
2015

21. Isolation of a full-length cDNA clone for human GTPcyclohydrolase I(GCH I)typel,a rate limiting enzyme for tetrahydrobiopterin biosynthesis, from pheochromocytoma and studies on its expression.

Author

Ohtsuki, Masatsugu, primary, Nomura, Takahide, additional, Matsui, Shigeru, additional, Hasegawa, Seiko, additional, Sumi-Ichinose, Chiho, additional, Nomura, Hiroko, additional, Ichinose, Hiroshi, additional, Nagatsu, Toshiharu, additional, Fujita, Keisuke, additional, and Hagino, Yasumichi, additional

Published
1996
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25. Analysis of alternative promoter in human aromatic L-amino acid decarboxylase gene.

Author

Sumi-Ichinose, Chiho, primary, Hasegawa, Seiko, additional, Ichinose, Hiroshi, additional, Sawada, Hirohide, additional, Kobayashi, Kazuto, additional, Sakai, Masao, additional, Fujii, Tetsuya, additional, Watanabe, Toshiko, additional, Nomura, Hiroko, additional, Nomura, Takahide, additional, Nagatsu, Ikuko, additional, Hagino, Yasumichi, additional, Fujita, Keisuke, additional, and Nagatsu, Toshiharu, additional

Published
1994
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