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1. Correction: SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians

Author

Miyashita, Akinori, primary, Koike, Asako, additional, Jun, Gyungah, additional, Wang, Li-San, additional, Takahashi, Satoshi, additional, Matsubara, Etsuro, additional, Kawarabayashi, Takeshi, additional, Shoji, Mikio, additional, Tomita, Naoki, additional, Arai, Hiroyuki, additional, Asada, Takashi, additional, Harigaya, Yasuo, additional, Ikeda, Masaki, additional, Amari, Masakuni, additional, Hanyu, Haruo, additional, Higuchi, Susumu, additional, Ikeuchi, Takeshi, additional, Nishizawa, Masatoyo, additional, Suga, Masaichi, additional, Kawase, Yasuhiro, additional, Akatsu, Hiroyasu, additional, Kosaka, Kenji, additional, Yamamoto, Takayuki, additional, Imagawa, Masaki, additional, Hamaguchi, Tsuyoshi, additional, Yamada, Masahito, additional, Morihara, Takashi, additional, Takeda, Masatoshi, additional, Takao, Takeo, additional, Nakata, Kenji, additional, Fujisawa, Yoshikatsu, additional, Sasaki, Ken, additional, Watanabe, Ken, additional, Nakashima, Kenji, additional, Urakami, Katsuya, additional, Ooya, Terumi, additional, Takahashi, Mitsuo, additional, Yuzuriha, Takefumi, additional, Serikawa, Kayoko, additional, Yoshimoto, Seishi, additional, Nakagawa, Ryuji, additional, Kim, Jong-Won, additional, Ki, Chang-Seok, additional, Won, Hong-Hee, additional, Na, Duk L., additional, Seo, Sang Won, additional, Mook-Jung, Inhee, additional, St. George-Hyslop, Peter, additional, Mayeux, Richard, additional, Haines, Jonathan L., additional, Pericak-Vance, Margaret A., additional, Yoshida, Makiko, additional, Nishida, Nao, additional, Tokunaga, Katsushi, additional, Yamamoto, Ken, additional, Tsuji, Shoji, additional, Kanazawa, Ichiro, additional, Ihara, Yasuo, additional, Schellenberg, Gerard D., additional, Farrer, Lindsay A., additional, and Kuwano, Ryozo, additional

Published
2013
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2. SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians

Author

Miyashita, Akinori, Koike, Asako, Jun, Gyungah, Wang, Li-San, Takahashi, Satoshi, Matsubara, Etsuro, Kawarabayashi, Takeshi, Shoji, Mikio, Tomita, Naoki, Arai, Hiroyuki, Asada, Takashi, Harigaya, Yasuo, Ikeda, Masaki, Amari, Masakuni, Hanyu, Haruo, Ikeuchi, Takeshi, Higuchi, Susumu, Nishizawa, Masatoyo, Suga, Masaichi, Kawase, Yasuhiro, Akatsu, Hiroyasu, Kosaka, Kenji, Yamamoto, Takayuki, Imagawa, Masaki, Yamada, Masahito, Hamaguchi, Tsuyoshi, Moriaha, Takashi, Takeda, Masatoshi, Takao, Takeo, Nakata, Kenji, Fujisawa, Yoshikatsu, Sasaki, Ken, Watanabe, Ken, Nakashima, Kenji, Urakami, Katsuya, Ooya, Terumi, Takahashi, Mitsuo, Yuzuriha, Takefumi, Serikawa, Kayoko, Yoshimoto, Seishi, Nakagawa, Ryuji, Kim, Jong-Won, Ki, Chang-Seok, Won, Hong-Hee, Na, Duk L., Seo, Sang Won, Mook-Jung, Inhee, St. George-Hyslop, Peter, Mayeux, Richard, Haines, Jonathan L., Pericak-Vance, Margaret A., Yoshida, Makiko, Nishida, Nao, Tokunaga, Katsushi, Yamamoto, Ken, Tsuji, Shoji, Kanazawa, Ichiro, Ihara, Yasuo, Schellenberg, Gerard D., Farrer, Lindsay A., Kuwano, Ryozo, and Consortium, The Alzheimer Disease Genetics

Subjects
Epidemiology, SORL1, Gene Identification and Analysis, Genome-wide association study, PICALM, 0302 clinical medicine, Japan, Genotype, Odds Ratio, Genetics, 0303 health sciences, Multidisciplinary, Chromosome Mapping, Neurology, Genetic Epidemiology, Medicine, Research Article, Science, Single-nucleotide polymorphism, Biology, Polymorphism, Single Nucleotide, White People, Molecular Genetics, 03 medical and health sciences, Asian People, Alzheimer Disease, Republic of Korea, Genome-Wide Association Studies, Humans, SNP, Genetic Predisposition to Disease, Allele, Alleles, LDL-Receptor Related Proteins, 030304 developmental biology, Chromosomes, Human, Pair 11, Haplotype, Membrane Transport Proteins, Human Genetics, Genetics of Disease, Genetic Polymorphism, Dementia, Population Genetics, 030217 neurology & neurosurgery, Genome-Wide Association Study
Abstract

To discover susceptibility genes of late-onset Alzheimer's disease (LOAD), we conducted a 3-stage genome-wide association study (GWAS) using three populations: Japanese from the Japanese Genetic Consortium for Alzheimer Disease (JGSCAD), Koreans, and Caucasians from the Alzheimer Disease Genetic Consortium (ADGC). In Stage 1, we evaluated data for 5,877,918 genotyped and imputed SNPs in Japanese cases (n = 1,008) and controls (n = 1,016). Genome-wide significance was observed with 12 SNPs in the APOE region. Seven SNPs from other distinct regions with p-values

Published
2013

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