Search

Your search keyword '"Pike, Meghan"' showing total 8 results
Start Over Author "Pike, Meghan" Search Limiters Full Text
8 results on '"Pike, Meghan"'

5. Performance of the eHealth decision support tool, MIPOGG, for recognising children with Li-Fraumeni, DICER1, Constitutional mismatch repair deficiency and Gorlin syndromes

Author

Hebert, Robyn, Cullinan, Noelle, Armstrong, Linlea, Blood, Katherine A, Brossard, Josee, Brunga, Ledia, Cacciotti, Chantel, Caswell, Kimberly, Cellot, Sonia, Coltin, Hallie, Deyell, Rebecca J, Felton, Kathleen, Fernandez, Conrad V, Fleming, Adam J, Gibson, Paul, Hammad, Rawan, Jabado, Nada, Johnston, Donna L, Lafay-Cousin, Lucie, Larouche, Valérie, Leblanc-Desrochers, Cassandra, Michaeli, Orli, Perrier, Renee, Pike, Meghan, Say, Jemma, Schiller, Ian, Toupin, Annie-Kim, Vairy, Stéphanie, van Engelen, Kalene, Waespe, Nicolas, Villani, Anita, Foulkes, William D, Malkin, David, Reichman, Lara, and Goudie, Catherine

Abstract

BackgroundCancer predisposition syndromes (CPSs) are responsible for at least 10% of cancer diagnoses in children and adolescents, most of which are not clinically recognised prior to cancer diagnosis. A variety of clinical screening guidelines are used in healthcare settings to help clinicians detect patients who have a higher likelihood of having a CPS. The McGill Interactive Pediatric OncoGenetic Guidelines (MIPOGG) is an electronic health decision support tool that uses algorithms to help clinicians determine if a child/adolescent diagnosed with cancer should be referred to genetics for a CPS evaluation.MethodsThis study assessed MIPOGG’s performance in identifying Li-Fraumeni, DICER1, Constitutional mismatch repair deficiency and Gorlin (nevoid basal cell carcinoma) syndromes in a retrospective series of 84 children diagnosed with cancer and one of these four CPSs in Canadian hospitals over an 18-year period.ResultsMIPOGG detected 82 of 83 (98.8%) evaluable patients with any one of these four genetic conditions and demonstrated an appropriate rationale for suggesting CPS evaluation. When compared with syndrome-specific clinical screening criteria, MIPOGG’s ability to correctly identify children with any of the four CPSs was equivalent to, or outperformed, existing clinical criteria respective to each CPS.ConclusionThis study adds evidence that MIPOGG is an appropriate tool for CPS screening in clinical practice. MIPOGG’s strength is that it starts with a specific cancer diagnosis and incorporates criteria relevant for associated CPSs, making MIPOGG a more universally accessible diagnostic adjunct that does not require in-depth knowledge of each CPS.

Published
2023
Full Text
View/download PDF

8. The WeThrive App and Its Impact on Adolescents Who Menstruate: Qualitative Study.

Author

MacNeil N, Price V, and Pike M

Subjects
Humans, Female, Adolescent, Menorrhagia psychology, Menstruation psychology, Surveys and Questionnaires, Nova Scotia, Quality of Life psychology, Mobile Applications, Qualitative Research
Abstract

Background: Heavy menstrual bleeding (HMB) affects up to 37% of adolescents. Without recognition, HMB can lead to other medical conditions resulting in diminished health-related quality of life. WeThrive, a new mobile health (mHealth) app, implements the pictorial bleeding assessment chart to identify HMB, and the adolescent Menstrual Bleeding Questionnaire to measure the effects of HMB on adolescents' health-related quality of life. If HMB is identified, WeThrive will connect users to local clinics for further assessment of their menstrual bleeding with a health care provider., Objective: This study aimed to describe adolescents' experiences using WeThrive app., Methods: This qualitative study was approved by the local Research Ethics Board in Halifax, Nova Scotia, and informed consent was provided by all participants. Individual semistructured interviews were held via videoconference with adolescents younger than 18 years, who had at least 1 menstrual period and had used WeThrive at least once. Interview transcripts were thematically analyzed by 2 investigators (MP and NMN) independently, and the κ statistic was calculated to determine the strength of correlation in themes., Results: Five adolescents (mean age 15.5, range 13-18 years), participated in the interviews. All participants stated that WeThrive helps them better understand their menstrual periods by predicting period onset, recognizing menstrual symptoms, and identifying HMB. Four themes were identified: (1) the importance of visual features and usability, (2) newly obtained knowledge using WeThrive, (3) feature use depends on menstrual health, and (4) trustworthiness. There was substantial agreement on the identified themes (κ=0.73)., Conclusions: WeThrive is visually appealing, and trustworthy, and helps users better understand their menstrual periods, including identifying HMB. By identifying HMB early, WeThrive has the potential to improve the recognition of bleeding disorders and iron deficiency in adolescents. WeThrive is a useful tool to help adolescents better understand their menstrual periods., (©Nora MacNeil, Victoria Price, Meghan Pike. Originally published in JMIR Formative Research (https://formative.jmir.org), 03.10.2024.)

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results