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12 results on '"Piva, Cristina"'

2. Predictive and prognostic value of inflammatory markers in locally advanced rectal cancer (PILLAR) – A multicentric analysis by the Italian Association of Radiotherapy and Clinical Oncology (AIRO) Gastrointestinal Study Group

Author

Chiloiro, Giuditta, Romano, Angela, Mariani, Silvia, Macchia, Gabriella, Giannarelli, Diana, Caravatta, Luciana, Franco, Pierfrancesco, Boldrini, Luca, Arcelli, Alessandra, Bacigalupo, Almalina, Belgioia, Liliana, Fontana, Antonella, Meldolesi, Elisa, Montesi, Giampaolo, Niespolo, Rita Marina, Palazzari, Elisa, Piva, Cristina, Valentini, Vincenzo, and Gambacorta, Maria Antonietta

Published
2023
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3. Variability of clinical target volume delineation for rectal cancer patients planned for neoadjuvant radiotherapy with the aid of the platform Anatom-e

Author

Franco, Pierfrancesco, Arcadipane, Francesca, Trino, Elisabetta, Gallio, Elena, Martini, Stefania, Iorio, Giuseppe Carlo, Piva, Cristina, Moretto, Francesco, Ruo Redda, Maria Grazia, Verna, Roberta, Tseroni, Vassiliki, Bona, Cristina, Pozzi, Gabriele, Fiandra, Christian, Ragona, Riccardo, Bertetto, Oscar, and Ricardi, Umberto

Published
2018
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7. Moderately Hypofractionated Radiotherapy with Simultaneous Integrated Boost in Prostate Cancer: A Comparative Study with Conventionally Fractionated Radiation

Author

Cante, Domenico, primary, Piva, Cristina, additional, Petrucci, Edoardo T. F., additional, Sciacero, Piera, additional, Ferrario, Silvia, additional, Pasquino, Massimo, additional, Casanova Borca, Valeria, additional, La Porta, Maria R., additional, and Franco, Pierfrancesco, additional

Published
2020
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9. Interobserver variability in clinical target volume delineation for primary mediastinal B-cell lymphoma

Author

Piva, Cristina, Genovesi, Domenico, Filippi, Andrea Riccardo, Balducci, Mario, Barra, Salvina, Buglione, Michela, Busetto, Mario, Ciammella, Patrizia, Franzone, Paola, De Sanctis, Vitaliana, Simontacchi, Gabriele, Fusella, Marco, Ricardi, Umberto, Balducci, Mario (ORCID:0000-0003-0398-9726), Piva, Cristina, Genovesi, Domenico, Filippi, Andrea Riccardo, Balducci, Mario, Barra, Salvina, Buglione, Michela, Busetto, Mario, Ciammella, Patrizia, Franzone, Paola, De Sanctis, Vitaliana, Simontacchi, Gabriele, Fusella, Marco, Ricardi, Umberto, and Balducci, Mario (ORCID:0000-0003-0398-9726)

Abstract

Purpose: The purpose of this study was to evaluate interobserver variability among radiation oncologists with experience in the field of lymphoma radiation therapy in the delineation of clinical target volume (CTV) in a challenging case of primary mediastinal B-cell lymphoma. Methods and materials: Ten experienced radiation oncologists were invited to a 1-day contouring session. The case of a 56-year-old man with primary mediastinal B-cell lymphoma with complete metabolic response after chemotherapy was chosen as the sample for the study. A brief presentation of his clinical history was given, together with guidelines for contouring. The 10 CTVs obtained were then compared in terms of variation in total volume and in craniocaudal, laterolateral, and anteroposterior diameters. The CTV with the best Dice similarity coefficient (DSC) between the union of all 10 CTVs and the individual CTV was considered the reference CTV, and the DSC and the Hausdorff distance (HD) for each volume compared with the reference CTV were then calculated. Results: A significant variability was found in total volume (mean, 498.3 cm3; range, 181.8-1003 cm3) and craniocaudal (median, 144.7 mm; range, 80.6-159 mm), laterolateral (median, 133.5 mm; range, 83.7-149.5 mm), and anteroposterior diameters (median, 136.2 mm; range, 84-150.5 mm). Analysis of the DSC and the HD showed a mean DSC of 0.53 (range, 0.31-0.74) and a mean HD of 6.4 cm (range, 1.8-14.8 cm). Conclusions: Results of this study strongly indicate the need to develop and share appropriate contouring guidelines among experts and suggest the promotion of specific educational activities to improve radiation therapy quality in both clinical trials and routine clinical practice.

Published
2015

11. Treatment Volume, Dose Prescription and Delivery Techniques for Dose-intensification in Rectal Cancer: A National Survey.

Author

Caravatta L, Lupattelli M, Mantello G, Gambacorta MA, Chiloiro G, DI Tommaso M, Rosa C, Gasparini L, Morganti AG, Picardi V, Niespolo RM, Osti MF, Montrone S, Simoni N, Boso C, Facchin F, Deidda MA, Piva C, Guida C, Ziccarelli L, Munoz F, Ivaldi GB, Marchetti V, Franzone P, Spatola C, Franco P, Donato V, and Genovesi D

Subjects
Female, Humans, Italy epidemiology, Lymphatic Metastasis, Magnetic Resonance Imaging, Male, Neoplasm Staging, Positron Emission Tomography Computed Tomography, Positron-Emission Tomography, Radiotherapy Dosage, Radiotherapy, Image-Guided adverse effects, Radiotherapy, Image-Guided methods, Radiotherapy, Image-Guided statistics & numerical data, Rectal Neoplasms diagnosis, Rectal Neoplasms mortality, Rectal Neoplasms pathology, Surveys and Questionnaires, Survival Analysis, Tumor Burden radiation effects, Practice Patterns, Physicians' statistics & numerical data, Radiotherapy Planning, Computer-Assisted adverse effects, Radiotherapy Planning, Computer-Assisted methods, Radiotherapy Planning, Computer-Assisted statistics & numerical data, Radiotherapy, Intensity-Modulated adverse effects, Radiotherapy, Intensity-Modulated methods, Radiotherapy, Intensity-Modulated statistics & numerical data, Rectal Neoplasms radiotherapy, Tumor Burden physiology
Abstract

Background/aim: The aim of the study was to investigate boost volume definition, doses, and delivery techniques for rectal cancer dose intensification., Patients and Methods: An online survey was made on 25 items (characteristics, simulation, imaging, volumes, doses, planning and treatment)., Results: Thirty-eight radiation oncologists joined the study. Twenty-one delivered long-course radiotherapy with dose intensification. Boost volume was delineated on diagnostic magnetic resonance imaging (MRI) in 18 centres (85.7%), and computed tomography (CT) and/or positron emission tomography-CT in 9 (42.8%); 16 centres (76.2%) performed co-registration with CT-simulation. Boost dose was delivered on gross tumor volume in 10 centres (47.6%) and on clinical target volume in 11 (52.4%). The most common total dose was 54-55 Gy (71.4%), with moderate hypofractionation (85.7%). Intensity-modulated radiotherapy (IMRT) was used in all centres, with simultaneous integrated boost in 17 (80.8%) and image-guidance in 18 (85.7%)., Conclusion: A high quality of treatment using dose escalation can be inferred by widespread multidisciplinary discussion, MRI-based treatment volume delineation, and radiation delivery relying on IMRT with accurate image-guided radiation therapy protocols., (Copyright © 2021 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.)

Published
2021
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12. Olfactory neuroblastoma treated with minimally invasive surgery and adjuvant radiotherapy: a case report and review of the literature.

Author

Cante D, Piva C, Sciacero P, Franco P, Petrucci E, Casanova Borca V, Marola F, Tubino L, Vellani G, and La Porta MR

Abstract

Olfactory neuroblastoma (ON) is a rare tumour of the olfactory neuroepithelium that is characterized by a pattern of slow growth and local recurrences. Combination of surgery and radiotherapy, with or without chemotherapy, is considered to be the standard of care for primary site disease. Recent literature supports the view that endoscopic resection followed by adjuvant radiotherapy correlates with better outcome. In this short communication, we present a case report of olfactory neuroblastoma arising in the right nasal sinus in a 34-year-old male. This patient was treated with endoscopic resection and external beam radiotherapy to the right nasal sinus with intensity-modulated radiation therapy (IMRT) technique. After 2 years follow-up, the patient is free of tumour without any late effect related to therapies. We believe that, in such patients, a treatment strategy including endoscopic resection followed by adjuvant radiotherapy may be effective and feasible and should be considered the gold standard of care.

Published
2018
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