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1. Availability and affordability of blood pressure-lowering medicines and the effect on blood pressure control in high-income, middle-income, and low-income countries: an analysis of the PURE study data

Author

Yusuf, S, Rangarajan, S, Teo, K K, Chow, C K, O'Donnell, M, Mente, A, Leong, D, Smyth, A, Joseph, P, Islam, S, Zhang, M, Hu, W, Ramasundarahettige, C, Wong, G, Dayal, L, Casanova, A, Dehghan, M, Lewis, G, Aliberti, A, Reyes, A, Zaki, A, Lewis, B, Zhang, B, Agapay, D, Hari, D, Milazzo, E, Ramezani, E, Hussain, F, Shifaly, F, Kay, I, Rimac, J, Swallow, J, Heldman, L, Mushtaha, M(a), Mushtaha, M(o), Trottier, M, Aoucheva, N, Kandy, N, Mackie, P, Solano, R, Chin, S, Ramacham, S, Shahrook, S, Trottier, S, Tongana, T, ElSheikh, W, Lindeman, J, McQueen, M, Hall, K, Keys, J, Wang, X, Keneth, J, Devanath, A, Diaz, R, Orlandini, A, Linetsky, B, Toscanelli, S, Casaccia, G, Maini Cuneo, JM, Rahman, O, Yusuf, R, Azad, AK, Rabbani, KA, Cherry, HM, Mannan, A, Hassan, I, Talukdar, AT, Tooheen, RB, Khan, MU, Sintaha, M, Choudhury, T, Haque, R, Parvin, S, Avezum, A, Oliveira, GB, Marcilio, CS, Mattos, AC, Teo, K, Dejesus, J, Elsheikh, W, Dagenais, G, Poirier, P, Turbide, G, Auger, D, De Bluts, A LeBlanc, Proulx, MC, Cayer, M, Bonneville, N, Lear, S, Gasevic, D, Corber, E, de Jong, V, Vukmirovich, I, Wielgosz, A, Fodor, G, Pipe, A, Shane, A, Lanas, F, Seron, P, Martinez, S, Valdebenito, A, Oliveros, M, Wei, Li, Lisheng, Liu, Chunming, Chen, Xingyu, Wang, Wenhua, Zhao, Hongye, Zhang, JiaXuan, Bo, Hu, Yi, Sun, Jian, Bo, Xiuwen, Zhao, Xiaohong, Chang, Tao, Chen, Hui, Chen, Qing, Deng, Xiaoru, Cheng, Xinye, He, Jian, Li, Juan, Li, Xu, Liu, Bing, Ren, Wei, Wang, Yang, Wang, Jun, Yang, Yi, Zhai, Manlu, Zhu, Fanghong, Lu, Jianfang, Wu, Yindong, Li, Yan, Hou, Liangqing, Zhang, Baoxia, Guo, Xiaoyang, Liao, Shiying, Zhang, BianRongwen, TianXiuzhen, Dong, Li, Di, Chen, Jianguo, Wu, Yize, Xiao, Tianlu, Liu, Peng, Zhang, Changlin, Dong, Ning, Li, Xiaolan, Ma, Yuqing, Yang, Rensheng, Lei, Minfan, Fu, Jing, He, Yu, Liu, Xiaojie, Xing, Qiang, Zhou, Lopez-Jaramillo, P, Lopez, PA Camacho, Garcia, R, Jurado, LJA, Gómez-Arbeláez, D, Arguello, JF, Dueñas, R, Silva, S, Pradilla, LP, Ramirez, F, Molina, DI, Cure-Cure, C, Perez, M, Hernandez, E, Arcos, E, Fernandez, S, Narvaez, C, Paez, J, Sotomayor, A, Garcia, H, Sanchez, G, David, T, Rico, A, Mony, P, Vaz, M, Bharathi, A V, Swaminathan, S, Shankar, K, Kurpad, AV, Jayachitra, KG, Kumar, N, Hospital, HAL, Mohan, V, Deepa, M, Parthiban, K, Anitha, M, Hemavathy, S, Rahulashankiruthiyayan, T, Anitha, D, Sridevi, K, Gupta, R, Panwar, RB, Mohan, I, Rastogi, P, Rastogi, S, Bhargava, R, Kumar, R, Thakur, J S, Patro, B, Lakshmi, PVM, Mahajan, R, Chaudary, P, Kutty, V Raman, Vijayakumar, K, Ajayan, K, Rajasree, G, Renjini, AR, Deepu, A, Sandhya, B, Asha, S, Soumya, HS, Kelishadi, R, Bahonar, A, Mohammadifard, N, Heidari, H, Yusoff, K, Ismail, TST, Ng, KK, Devi, A, Nasir, NM, Yasin, MM, Miskan, M, Rahman, EA, Arsad, MKM, Ariffin, F, Razak, SA, Majid, FA, Bakar, NA, Yacob, MY, Zainon, N, Salleh, R, Ramli, MKA, Halim, NA, Norlizan, SR, Ghazali, NM, Arshad, MN, Razali, R, Ali, S, Othman, HR, Hafar, CWJCW, Pit, A, Danuri, N, Basir, F, Zahari, SNA, Abdullah, H, Arippin, MA, Zakaria, NA, Noorhassim, I, Hasni, MJ, Azmi, MT, Zaleha, MI, Hazdi, KY, Rizam, AR, Sazman, W, Azman, A, Khatib, R, Khammash, U, Khatib, A, Giacaman, R, Iqbal, R, Afridi, A, Khawaja, R, Raza, A, Kazmi, K, Dans, A, Co, HU, Sanchez, JT, Pudol, L, Zamora-Pudol, C, Palileo-Villanueva, LAM, Aquino, MR, Abaquin, C, Pudol, SL, Cabral, ML, Zatonski, W, Szuba, A, Zatonska, K, Ilow#, R, Ferus, M, Regulska-Ilow, B, Różańska, D, Wolyniec, M, AlHabib, KF, Hersi, A, Kashour, T, Alfaleh, H, Alshamiri, M, Altaradi, HB, Alnobani, O, Bafart, A, Alkamel, N, Ali, M, Abdulrahman, M, Nouri, R, Kruger, A, Voster, H H, Schutte, A E, Wentzel-Viljoen, E, Eloff, FC, de Ridder, H, Moss, H, Potgieter, J, Roux, AA, Watson, M, de Wet, G, Olckers, A, Jerling, JC, Pieters, M, Hoekstra, T, Puoane, T, Igumbor, E, Tsolekile, L, Sanders, D, Naidoo, P, Steyn, N, Peer, N, Mayosi, B, Rayner, B, Lambert, V, Levitt, N, Kolbe-Alexander, T, Ntyintyane, L, Hughes, G, Swart, R, Fourie, J, Muzigaba, M, Xapa, S, Gobile, N, Ndayi, K, Jwili, B, Ndibaza, K, Egbujie, B, Rosengren, A, Boström, K Bengtsson, Lindblad, U, Langkilde, P, Gustavsson, A, Andreasson, M, Snällman, M, Wirdemann, L, Pettersson, K, Moberg, E, Yeates, K, Sleeth, J, Kilonzo, K, Oguz, A, Akalin, AAK, Calik, KBT, Imeryuz, N, Temizhan, A, Alphan, E, Gunes, E, Sur, H, Karsidag, K, Gulec, S, Altuntas, Y, Yusufali, AM, Almahmeed, W, Swidan, H, Darwish, EA, Hashemi, ARA, Al-Khaja, N, Muscat-Baron, JM, Ahmed, SH, Mamdouh, TM, Darwish, WM, Abdelmotagali, MHS, Awed, SA Omer, Movahedi, GA, Shaibani, H Al, Gharabou, RIM, Youssef, DF, Nawati, AZS, Salah, ZAR Abu, Abdalla, RFE, Shuwaihi, SM Al, Omairi, MA Al, Cadigal, OD, Alejandrino, R.S., Chifamba, J, Gwaunza, L, Terera, G, Mahachi, C, Murambiwa, P, Machiweni, T, Mapanga, R, Attaei, Marjan W, Khatib, Rasha, McKee, Martin, Lear, Scott, Dagenais, Gilles, Igumbor, Ehimario U, AlHabib, Khalid F, Kaur, Manmeet, Kruger, Lanthe, Teo, Koon, Lanas, Fernando, Yusoff, Khalid, Oguz, Aytekin, Gupta, Rajeev, Yusufali, Afzalhussein M, Bahonar, Ahmad, Kutty, Raman, Rosengren, Annika, Mohan, Viswanathan, Avezum, Alvaro, Yusuf, Rita, Szuba, Andrzej, Rangarajan, Sumathy, Chow, Clara, and Yusuf, Salim

Published
2017
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2. Household, community, sub-national and country-level predictors of primary cooking fuel switching in nine countries from the PURE study

Author

Shupler, Matthew, Hystad, Perry, Gustafson, Paul, Rangarajan, Sumathy, Mushtaha, Maha, Jayachtria, KG, Mony, Prem K, Mohan, Deepa, Kumar, Parthiban, Lakshmi, PVM, Sagar, Vivek, Gupta, Rajeev, Mohan, Indu, Nair, Sanjeev, Varma, Ravi Prasad, Li, Wei, Hu, Bo, You, Kai, Ncube, Tatenda, Ncube, Brian, Chifamba, Jephat, West, Nicola, Yeates, Karen, Iqbal, Romaina, Khawaja, Rehman, Yusuf, Rita, Khan, Afreen, Seron, Pamela, Lanas, Fernando, Lopez-Jaramillo, Patricio, Camacho, Paul A, Puoane, Thandi, Yusuf, Salim, Brauer, Michael, Yusuf, S, Rangarajan, S, Teo, KK, Anand, SS, Chow, CK, O'Donnell, M, Mente, A, Leong, D, Smyth, A, Joseph, P, Duong, M, Kurmi, O, D'Souza, R, Walli-Attaei, M, Balaji, B, Naito, R, Islam, S, Hu, W, Ramasundarahettige, C, Sheridan, P, Bangdiwala, S, Dyal, L, Casanova, A, Dehghan, M, Lewis, G, Agapay, D, Aliberti, A, Aoucheva, N, Arshad, A, Reyes, A, Bideri, B, Buthool, R, Chin, S, Di Marino, M, Frances, R, Gopal, S, Jakymyshn, M, Kandy, N, Kay, I, Lindeman, J, McAlpine, G, McNeice, E, Mushtaha, M, Patel, R, Pattath, D, Ramacham, S, Ramezani, E, Rimac, J, Shifaly, F, Swallow, J, Trottier, M, Trottier, S, Solano, R, Zaki, A, Zhang, B, Zhang, V, Rahman, O, Yusuf, R, Ahmed, SAKS, Choudhury, T, Sintaha, M, Khan, A, Alam, O, Nayeem, N, Mitra, SN, Pasha, F, Lanas, F, Seron, P, Oliveros, MJ, Cazor, F, Palacios, Y, Wei, Li, Lisheng, Liu, Jian, Bo, Bo, Hu, Lu, Yin, Wenhua, Zhao, Hongye, Zhang, Xuan, Jia, Yi, Sun, Xingyu, Wang, Xiuwen, Zhao, Xinye, He, Tao, Chen, Hui, Chen, Xiaohong, Chang, Qing, Deng, Xiaoru, Cheng, Liya, Xie, Zhiguang, Liu, Juan, Li, Jian, Li, Xu, Liu, Bing, Ren, Wei, Wang, Yang, Wang, Jun, Yang, Yi, Zhai, Manlu, Zhu, Fanghong, Lu, Jianfang, Wu, Yindong, Li, Yan, Hou, Liangqing, Zhang, Baoxia, Guo, Xiaoyang, Liao, Shiying, Zhang, BianRongwen, Xiuzhen, Tian, Dong, Li, Di, Chen, Jianguo, Wu, Yize, Xiao, Tianlu, Liu, Peng, Zhang, Changlin, Dong, Ning, Li, Xiaolan, Ma, Yuqing, Yang, Rensheng, Lei, Minfan, Fu, Jing, He, Yu, Liu, Xiaojie, Xing, Qiang, Zhou, Lopez-Jaramillo, P, Camacho-Lopez, PA, Otero-Wandurraga, J, Molina, DI, Cure-Cure, C, Perez, M, Hernandez, E, Arcos, E, Narvaez, C, Sotomayor, A, Garcia, H, Sanchez, G, Cotes, F, Rico, A, Duran, M, Torres, C, Mony, P, Vaz, M, Swaminathan, S, Shankar, K, Kurpad, AV, Jayachitra, KG, Kumar, N, Hospital, HAL, Mohan, V, Deepa, M, Parthiban, K, Anitha, M, Hemavathy, S, Rahulashankiruthiyayan, T, Anitha, D, Anjana, RM, Dhanasekar, R, Sureshkumar, S, Sridevi, K, Gupta, R, Panwar, RB, Mohan, I, Rastogi, P, Rastogi, S, Bhargava, R, Kumar, R, Thakur, JS, Patro, B, Mahajan, R, Chaudary, P, Kutty, V Raman, Vijayakumar, K, Ajayan, K, Rajasree, G, Renjini, AR, Deepu, A, Sandhya, B, Asha, S, Soumya, HS, Kaur, M, Sagar, V, Iqbal, R, Khawaja, R, Azam, I, Kazmi, K, Kruger, L, Kruger, A, Bestra, P, Voster, HH, Schutte, AE, Wentzel-Viljoen, E, Eloff, FC, de Ridder, H, Moss, H, Potgieter, J, Roux, AA, Watson, M, de Wet, G, Olckers, A, Jerling, JC, Pieters, M, Hoekstra, T, Puoane, T, Swart, R, Igumbor, E, Tsolekile, L, Ndayi, K, Sanders, D, Naidoo, P, Steyn, N, Peer, N, Mayosi, B, Rayner, B, Lambert, V, Levitt, N, Kolbe-Alexander, T, Ntyintyane, L, Hughes, G, Fourie, J, Muzigaba, M, Xapa, S, Gobile, N, Jwili, B, Ndibaza, K, Egbujie, B, Yeates, K, Oresto, M, West, N, Chifamba, J, Ncube, T, Ncube, B, Chimhete, C, Neya, GK, Manenji, T, Gwaunza, L, Mapara, V, Terera, G, Mahachi, C, Murambiwa, P, Mapanga, R, Chinhara, A, Epidemiolo, Prospective Urban Rural, and Everest

Subjects
010504 meteorology & atmospheric sciences, Air pollution, 010501 environmental sciences, medicine.disease_cause, 01 natural sciences, Agricultural economics, Article, Country level, 11. Sustainability, medicine, Coal, Baseline (configuration management), 0105 earth and related environmental sciences, General Environmental Science, 2. Zero hunger, Kerosene, Renewable Energy, Sustainability and the Environment, business.industry, Multilevel model, 1. No poverty, Public Health, Environmental and Occupational Health, 13. Climate action, Environmental science, Survey data collection, Community setting, business
Abstract

Digital, Introduction. Switching from polluting (e.g. wood, crop waste, coal) to clean (e.g. gas, electricity) cooking fuels can reduce household air pollution exposures and climate-forcing emissions. While studies have evaluated specific interventions and assessed fuel-switching in repeated cross-sectional surveys, the role of different multilevel factors in household fuel switching, outside of interventions and across diverse community settings, is not well understood. Methods. We examined longitudinal survey data from 24 172 households in 177 rural communities across nine countries within the Prospective Urban and Rural Epidemiology study. We assessed household-level primary cooking fuel switching during a median of 10 years of follow up (∼2005–2015). We used hierarchical logistic regression models to examine the relative importance of household, community, sub-national and national-level factors contributing to primary fuel switching. Results. One-half of study households (12 369) reported changing their primary cooking fuels between baseline and follow up surveys. Of these, 61% (7582) switched from polluting (wood, dung, agricultural waste, charcoal, coal, kerosene) to clean (gas, electricity) fuels, 26% (3109) switched between different polluting fuels, 10% (1164) switched from clean to polluting fuels and 3% (522) switched between different clean fuels. Among the 17 830 households using polluting cooking fuels at baseline, household-level factors (e.g. larger household size, higher wealth, higher education level) were most strongly associated with switching from polluting to clean fuels in India; in all other countries, community-level factors (e.g. larger population density in 2010, larger increase in population density between 2005 and 2015) were the strongest predictors of polluting-to-clean fuel switching. Conclusions. The importance of community and sub-national factors relative to household characteristics in determining polluting-to-clean fuel switching varied dramatically across the nine countries examined. This highlights the potential importance of national and other contextual factors in shaping large-scale clean cooking transitions among rural communities in low- and middle-income countries., Ciencias Médicas y de la Salud

Published
2019

3. Causes and predictors of mortality in Asian Indians with and without diabetes-10 year follow-up of the Chennai Urban Rural Epidemiology Study (CURES - 150).

Author

Anjana RM, Unnikrishnan R, Mugilan P, Jagdish PS, Parthasarathy B, Deepa M, Loganathan G, Kumar RA, Rahulashankiruthiyayan T, Uma Sankari G, Venkatesan U, Mohan V, and Shanthi Rani CS

Subjects
Aged, Asian People, Cohort Studies, Coronary Artery Disease diagnosis, Coronary Artery Disease epidemiology, Coronary Artery Disease physiopathology, Diabetes Mellitus diagnosis, Diabetes Mellitus epidemiology, Diabetes Mellitus physiopathology, Diabetic Nephropathies diagnosis, Diabetic Nephropathies epidemiology, Diabetic Nephropathies physiopathology, Female, Follow-Up Studies, Humans, Incidence, India epidemiology, Male, Middle Aged, Myocardial Ischemia diagnosis, Myocardial Ischemia epidemiology, Myocardial Ischemia physiopathology, Prevalence, Prognosis, Proportional Hazards Models, Risk Factors, Rural Population, Thinness diagnosis, Thinness physiopathology, Urban Population, Coronary Artery Disease mortality, Diabetes Mellitus mortality, Diabetic Nephropathies mortality, Myocardial Ischemia mortality
Abstract

Background: The incidence and prevalence of diabetes is increasing worldwide and it is the fifth leading cause of mortality accounting for over 3.8 million deaths annually. Despite the enormity of the diabetes-related health burdens, very few studies have evaluated the factors associated with mortality among people with diabetes in India. We sought to study the causes and predictors of mortality among urban Asian Indians with and without diabetes., Methods and Findings: Of 2273 adults (27,850 person-years of follow-up) from the 10-year follow-up of the Chennai Urban Rural Epidemiology Study (CURES), the cause of death could be ascertained in 552 individuals out of the 671 who had died (response rate 82.3%). Verbal autopsy was obtained from the family members of the deceased and this was adjudicated by trained physicians. The age-standardized mortality rate was 28.2 (95%CI 25.9-30.6) per 100,000 population. Mortality rates were significantly higher in individuals with diabetes compared to those without [27.9(95% CI 25.5-30.6) vs. 8.0 (6.6-9.9) per 1000 person years]. Compared to individuals of normal body mass index, underweight individuals had higher risk of mortality (Hazard ratio 1.49; 95% CI 1.11-2.0), whereas overweight and obese individuals did not show a higher risk. The population-attributable risk for all-cause mortality in the entire study cohort was highest for ischemic heart disease and diabetes. The excess mortality attributable to diabetes was highest in the age group of 51 to 70 years, and was mostly accounted for by renal disease (Rate ratio 5.68, 95%CI 2.43-6.23), ischemic heart disease (4.23,2.78-6.67), and cerebrovascular disease (4.00,1.87-9.81)., Conclusion: Underweight (but not overweight or obesity) was strongly associated with mortality in this Asian Indian population. Ischemic heart disease and diabetes contributed the most to risk for all cause mortality. Excess mortality due to diabetes was higher in relatively younger individuals and was mostly accounted for by renal disease., Competing Interests: The authors have declared that no competing interests exist.

Published
2018
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