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7. Micron-scale D/H heterogeneity in chondrite matrices: a signature of the pristine solar system water?

Author

Piani, Laurette, Robert, François, and Remusat, Laurent

Subjects
Astrophysics - Earth and Planetary Astrophysics
Abstract

Organic matter and hydrous silicates are intimately mixed in the matrix of chondrites and in-situ determination of their individual D/H ratios is therefore challenging. Nevertheless, the D/H ratio of each pure component in this mixture should yield a comprehensible signature of the origin and evolution of water and organic matter in our solar system. We measured hydrogen isotope ratios of organic and hydrous silicates in the matrices of two carbonaceous chondrites (Orgueil CI1 and Renazzo CR2) and one unequilibrated ordinary chondrite (Semarkona, LL3.0). A novel protocol was adopted, involving NanoSIMS imaging of H isotopes of monoatomatic ($H^-$) and molecular ($OH^-$) secondary ions collected at the same location. This allowed the most enriched component with respect to D to be identified in the mixture. Using this protocol, we found that in carbonaceous chondrites the isotopically homogeneous hydrous silicates are mixed with D-rich organic matter. The opposite was observed in Semarkona. Hydrous silicates in Semarkona display highly heterogeneous D/H ratios, ranging from $150$ to $1800$ ${\times}$ $10^{-6}$ (${\delta}D_{SMOW} = -40$ to $10,600$ permil). Organic matter in Semarkona does not show such large isotopic variations. This suggests limited isotopic exchange between the two phases during aqueous alteration. Our study greatly expands the range of water isotopic values measured so far in solar system objects. This D-rich water reservoir was sampled by the LL ordinary chondrite parent body and an estimate (up to 9 %) of its relative contribution to the D/H ratio of water in Oort cloud family comets is proposed., Comment: 40 pages, 8 figures, 2 tables, one supplement

Published
2015
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8. Structure, composition, and location of organic matter in the enstatite chondrite Sahara 97096 (EH3)

Author

Piani, Laurette, Robert, FrançOis, Beyssac, Olivier, Binet, Laurent, Bourot-Denise, Michèle, Derenne, Sylvie, Guillou, Corentin Le, Marrocchi, Yves, Mostefaoui, Smail, Rouzaud, Jean-Noel, and Thomen, Aurelien

Subjects
Astrophysics - Earth and Planetary Astrophysics
Abstract

The insoluble organic matter (IOM) of an unequilibrated enstatite chondrite Sahara (SAH) 97096 has been investigated using a battery of analytical techniques. As the enstatite chondrites are thought to have formed in a reduced environment at higher temperatures than carbonaceous chondrites, they constitute an interesting comparative material to test the heterogeneities of the IOM in the solar system and to constrain the processes that could affect IOM during solar system evolution. The SAH 97096 IOM is found in situ: as submicrometer grains in the network of fine-grained matrix occurring mostly around chondrules and as inclusions in metallic nodules, where the carbonaceous matter appears to be more graphitized. IOM in these two settings has very similar $\delta^{15}N$ and $\delta^{13}C$; this supports the idea that graphitized inclusions in metal could be formed by metal catalytic graphitization of matrix IOM. A detailed comparison between the IOM extracted from a fresh part and a terrestrially weathered part of SAH 97096 shows the similarity between both IOM samples in spite of the high degree of mineral alteration in the latter. The isolated IOM exhibits a heterogeneous polyaromatic macromolecular structure, sometimes highly graphitized, without any detectable free radicals and deuterium-heterogeneity and having mean H- and N-isotopic compositions in the range of values observed for carbonaceous chondrites. It contains some submicrometer-sized areas highly enriched in $^{15}N$ ($\delta^{15}N$ up to 1600 permil). These observations reinforce the idea that the IOM found in carbonaceous chondrites is a common component widespread in the solar system. Most of the features of SAH 97096 IOM could be explained by the thermal modification of this main component.

Published
2015
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9. Molecular preservation of 1.88 Ga Gunflint organic microfossils as a function of temperature and mineralogy.

Author

Alleon, Julien, Bernard, Sylvain, Le Guillou, Corentin, Marin-Carbonne, Johanna, Pont, Sylvain, Beyssac, Olivier, McKeegan, Kevin D, and Robert, François

Subjects
Carbonates, Silicon Dioxide, Quartz, Microscopy, Electron, Transmission, Preservation, Biological, X-Ray Diffraction, Spectrum Analysis, Raman, Temperature, Geologic Sediments, Paleontology, Fossils, Ontario, Minnesota, X-Ray Absorption Spectroscopy, Microscopy, Electron, Transmission, Preservation, Biological, Spectrum Analysis, Raman
Abstract

The significant degradation that fossilized biomolecules may experience during burial makes it challenging to assess the biogenicity of organic microstructures in ancient rocks. Here we investigate the molecular signatures of 1.88 Ga Gunflint organic microfossils as a function of their diagenetic history. Synchrotron-based XANES data collected in situ on individual microfossils, at the submicrometre scale, are compared with data collected on modern microorganisms. Despite diagenetic temperatures of ∼150-170 °C deduced from Raman data, the molecular signatures of some Gunflint organic microfossils have been exceptionally well preserved. Remarkably, amide groups derived from protein compounds can still be detected. We also demonstrate that an additional increase of diagenetic temperature of only 50 °C and the nanoscale association with carbonate minerals have significantly altered the molecular signatures of Gunflint organic microfossils from other localities. Altogether, the present study provides key insights for eventually decoding the earliest fossil record.

Published
2016

11. Deuterium Fractionation: the Ariadne's Thread from the Pre-collapse Phase to Meteorites and Comets today

Author

Ceccarelli, Cecilia, Caselli, Paola, Bockelee-Morvan, Dominique, Mousis, Olivier, Pizzarello, Sandra, Robert, Francois, and Semenov, Dmitry

Subjects
Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Solar and Stellar Astrophysics
Abstract

The Solar System formed about 4.6 billion years ago from a condensation of matter inside a molecular cloud. Trying to reconstruct what happened is the goal of this chapter. For that, we put together our understanding of Galactic objects that will eventually form new suns and planetary systems, with our knowledge on comets, meteorites and small bodies of the Solar System today. Our specific tool is the molecular deuteration, namely the amount of deuterium with respect to hydrogen in molecules. This is the Ariadne's thread that helps us to find the way out from a labyrinth of possible histories of our Solar System. The chapter reviews the observations and theories of the deuterium fractionation in pre-stellar cores, protostars, protoplanetary disks, comets, interplanetary dust particles and meteorites and links them together trying to build up a coherent picture of the history of the Solar System formation. We emphasise the interdisciplinary nature of the chapter, which gathers together researchers from different communities with the common goal of understanding the Solar System history., Comment: Accepted for publication as a chapter in Protostars and Planets VI, University of Arizona Press (2014), eds. H. Beuther, R. Klessen, C. Dullemond, Th. Henning

Published
2014
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13. Water transport in protoplanetary disks and the hydrogen isotopic composition of chondrites

Author

Jacquet, Emmanuel and Robert, François

Subjects
Astrophysics - Earth and Planetary Astrophysics
Abstract

The D/H ratios of carbonaceous chondrites, believed to reflect that of water in the inner early solar system, are intermediate between the protosolar value and that of most comets. The isotopic composition of cometary water has been accounted for by several models where the isotopic composition of water vapor evolved by isotopic exchange with hydrogen gas in the protoplanetary disk. However, the position and the wide variations of the distribution of D/H ratios in carbonaceous chondrites have yet to be explained. In this paper, we assume that the D/H composition of cometary ice was achieved in the disk building phase and model the further isotopic evolution of water in the inner disk in the classical T Tauri stage. Reaction kinetics compel isotopic exchange between water and hydrogen gas to stop at $\sim$500 K, but equilibrated water can be transported to the snow line (and beyond) via turbulent diffusion and consequently mix with isotopically comet-like water. Under certain simplifying assumptions, we calculate analytically this mixing and the resulting probability distribution function of the D/H ratio of ice accreted in planetesimals and compare it with observational data. The distribution essentially depends on two parameters: the radial Schmidt number Sc$_R$, which ratios the efficiencies of angular momentum transport and turbulent diffusion, and the range of heliocentric distances of accretion sampled by chondrites. The minimum D/H ratio of the distribution corresponds to the composition of water condensed at the snow line, which is primarily set by Sc$_R$. Observations constrain the latter to low values (0.1-0.3), which suggests that turbulence in the planet-forming region was hydrodynamical in nature, as would be expected in a dead zone. Such efficient outward diffusion would also account for the presence of high-temperature minerals in comets., Comment: 13 pages, 7 figures, accepted to Icarus

Published
2013
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18. Transcriptional Regulatory Networks in Saccharomyces cerevisiae

Author

Lee, Tong Ihn, Rinaldi, Nicola J., Robert, François, Odom, Duncan T., Bar-Joseph, Ziv, Gerber, Georg K., Hannett, Nancy M., Harbison, Christopher T., Thompson, Craig M., Simon, Itamar, Zeitlinger, Julia, Jennings, Ezra G., Murray, Heather L., Gordon, D. Benjamin, Ren, Bing, Wyrick, John J., Tagne, Jean-Bosco, Volkert, Thomas L., Fraenkel, Ernest, Gifford, David K., and Young, Richard A.

Published
2002

19. Nuclear receptor ERRα and coactivator PGC-1β are effectors of IFN-γ-induced host defense

Author

Sonoda, Junichiro, Laganière, Josée, Mehl, Isaac R, Barish, Grant D, Chong, Ling-Wa, Li, Xiangli, Scheffler, Immo E, Mock, Dennis C, Bataille, Alain R, Robert, François, Lee, Chih-Hao, Giguère, Vincent, and Evans, Ronald M

Subjects
Biochemistry and Cell Biology, Biological Sciences, Emerging Infectious Diseases, Genetics, Vaccine Related, Foodborne Illness, Infectious Diseases, Aetiology, 2.1 Biological and endogenous factors, Animals, Base Sequence, Carrier Proteins, DNA, Female, Gene Expression, In Vitro Techniques, Interferon-gamma, Listeria monocytogenes, Macrophage Activation, Macrophages, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Mitochondria, Models, Biological, RNA-Binding Proteins, Reactive Oxygen Species, Receptors, Estrogen, Recombinant Proteins, Signal Transduction, mitochondria, macrophages, oxidative metabolism, reactive oxygen species, Medical and Health Sciences, Psychology and Cognitive Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences, Psychology
Abstract

Macrophage activation by the proinflammatory cytokine interferon-gamma (IFN-gamma) is a critical component of the host innate response to bacterial pathogenesis. However, the precise nature of the IFN-gamma-induced activation pathway is not known. Here we show using genome-wide expression and chromatin-binding profiling that IFN-gamma induces the expression of many nuclear genes encoding mitochondrial respiratory chain machinery via activation of the nuclear receptor ERR alpha (estrogen-related receptor alpha, NR3B1). Studies with macrophages lacking ERR alpha demonstrate that it is required for induction of mitochondrial reactive oxygen species (ROS) production and efficient clearance of Listeria monocytogenes (LM) in response to IFN-gamma. As a result, mice lacking ERR alpha are susceptible to LM infection, a phenotype that is localized to bone marrow-derived cells. Furthermore, we found that IFN-gamma-induced activation of ERR alpha depends on coactivator PGC-1 beta (peroxisome proliferator-activated receptor gamma coactivator-1 beta), which appears to be a direct target for the IFN-gamma/STAT-1 signaling cascade. Thus, ERR alpha and PGC-1 beta act together as a key effector of IFN-gamma-induced mitochondrial ROS production and host defense.

Published
2007

20. Genome-Wide Location and Function of DNA Binding Proteins

Author

Ren, Bing, Robert, François, Wyrick, John J., Aparicio, Oscar, Jennings, Ezra G., Simon, Itamar, Zeitlinger, Julia, Schreiber, Jörg, Hannett, Nancy, Kanin, Elenita, Volkert, Thomas L., Wilson, Christopher J., Bell, Stephen P., and Young, Richard A.

Published
2000

24. Triple silicon isotope insights into the formation of Precambrian cherts

Author

Sun, Haoxuan, Chaussidon, Marc, Robert, François, Tian, Shengyu, Deng, Zhengbin, Moynier, Frédéric, Sun, Haoxuan, Chaussidon, Marc, Robert, François, Tian, Shengyu, Deng, Zhengbin, and Moynier, Frédéric

Abstract

Cherts are pervasive in the Precambrian and their O and Si isotopic compositions have been used extensively for reconstructing seawater paleo-temperatures. However, these reconstructions are obscured by the fact that cherts exhibit, at a given age, a large isotopic (O and Si) heterogeneity at bulk and micrometer scales. This is understood as reflecting the fact that cherts are an assemblage of silica precursors having different origins, and that diagenesis and metamorphism have modified the isotopic compositions acquired during the last equilibration with seawater. To test the contributions of the different processes that control the Si isotopic composition of cherts, we developed high-precision triple Si isotope measurements by Multicollector-Inductively Coupled-Plasma Mass-Spectrometer (MC-ICP-MS). This approach allows to identify deviations from the equilibrium Si isotopic fractionation at the level of a few ppm. Triple Si isotope data combined with trace elements and O isotope data in Precambrian cherts demonstrate that three different sources of silica were involved in the formation of cherts, and that both equilibrium and kinetic isotopic fractionation took place for Si. Archean seawater is predicted to have a triple Si isotopic composition kinetically fractionated relative to bulk silicate Earth. This requires a large kinetic isotopic fractionation during hydrothermalism of the oceanic crust and appears consistent with warm oceans in the Precambrian. However more work is required on the triple isotope systematics of Si inputs and output to seawater by rivers and authigenic clays formation. Triple Si isotope variations can thus be used as a new tool to unravel the origin of cherts and of their O and Si isotopic compositions. The present evidence of kinetic isotopic fractionations for Si isotopes also implies that Si isotopes should be associated to triple O isotope for paleotemperature reconstructions.

Published
2023

26. Un outil d'intelligence collective : le Vrai débat

Author

Dartigues, Laurent, Robert, François, Ventresque, Vincent, Zancarini, Jean-Claude, Triangle : action, discours, pensée politique et économique (TRIANGLE), École normale supérieure de Lyon (ENS de Lyon)-Université Lumière - Lyon 2 (UL2)-Sciences Po Lyon - Institut d'études politiques de Lyon (IEP Lyon), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Centre National de la Recherche Scientifique (CNRS), Institut d’Histoire des Représentations et des Idées dans les Modernités (IHRIM), École normale supérieure de Lyon (ENS de Lyon)-Université Lumière - Lyon 2 (UL2)-Université Jean Moulin - Lyon 3 (UJML), Université de Lyon-Université de Lyon-Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Université Jean Monnet - Saint-Étienne (UJM)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA), Béroud, Sophie, Dufresne, Anne, Gobin, Corinne, Zune, Marc, Dartigues, Laurent, Centre National de la Recherche Scientifique (CNRS)-Sciences Po Lyon - Institut d'études politiques de Lyon (IEP Lyon), Université de Lyon-Université de Lyon-Université Jean Monnet [Saint-Étienne] (UJM)-Université Lumière - Lyon 2 (UL2)-École normale supérieure - Lyon (ENS Lyon), École normale supérieure - Lyon (ENS Lyon)-Université Lumière - Lyon 2 (UL2)-Université Jean Moulin - Lyon 3 (UJML), and Université de Lyon-Université de Lyon-Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Université Jean Monnet [Saint-Étienne] (UJM)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA)

Subjects
[SHS.HISPHILSO]Humanities and Social Sciences/History, Philosophy and Sociology of Sciences, gilets jaunes, [SHS.HISPHILSO] Humanities and Social Sciences/History, Philosophy and Sociology of Sciences, consultation numérique, Le Vrai débat
Abstract

International audience; "Les analyses que nous présentons ici rendent compte d’un travail collectif mené en février 2019 par des membres du laboratoire 'Triangle' en réponse à des membres de l’équipe du Vrai débat qui avait lancé le 7 février un appel aux chercheurs pour traiter de manière indépendante les données de leur consultation numérique . Utilisant le même logiciel que la plateforme du Grand débat (que la société Cap Collectif leur avait fourni gratuitement), une quinzaine de GJ venus de toute la France ont ouvert une plateforme de démocratie participative, qu’ils ont définie comme un « outil d’intelligence collective », et configurée de manière à laisser un maximum de liberté aux citoyens souhaitant s’y exprimer. "

Published
2022

36. Comet 81p/Wild 2 under a Microscope

Author

Brownlee, Don, Tsou, Peter, Aléon, Jérôme, Alexander, Conel M. O'D., Araki, Tohru, Bajt, Sasa, Baratta, Giuseppe A., Bastien, Ron, Bland, Phil, Bleuet, Pierre, Borg, Janet, Bradley, John P., Brearley, Adrian, Brenker, F., Brennan, Sean, Bridges, John C., Browning, Nigel D., Brucato, John R., Bullock, E., Burchell, Mark J., Busemann, Henner, Butterworth, Anna, Chaussidon, Marc, Cheuvront, Allan, Chi, Miaofang, Cintala, Mark J., Clark, B. C., Clemett, Simon J., Cody, George, Colangeli, Luigi, Cooper, George, Cordier, Patrick, Daghlian, C., Dai, Zurong, D'Hendecourt, Louis, Djouadi, Zahia, Dominguez, Gerardo, Duxbury, Tom, Dworkin, Jason P., Ebel, Denton S., Economou, Thanasis E., Fakra, Sirine, Fairey, Sam A. J., Fallon, Stewart, Ferrini, Gianluca, Ferroir, T., Fleckenstein, Holger, Floss, Christine, Flynn, George, Franchi, Ian A., Fries, Marc, Gainsforth, Z., Gallien, J.-P., Genge, Matt, Gilles, Mary K., Gillet, Philipe, Gilmour, Jamie, Glavin, Daniel P., Gounelle, Matthieu, Grady, Monica M., Graham, Giles A., Grant, P. G., Green, Simon F., Grossemy, Faustine, Grossman, Lawrence, Grossman, Jeffrey N., Guan, Yunbin, Hagiya, Kenji, Harvey, Ralph, Heck, Philipp, Herzog, Gregory F., Hoppe, Peter, Hörz, Friedrich, Huth, Joachim, Hutcheon, Ian D., Ignatyev, Konstantin, Ishii, Hope, Ito, Motoo, Jacob, Damien, Jacobsen, Chris, Jacobsen, Stein, Jones, Steven, Joswiak, David, Jurewicz, Amy, Kearsley, Anton T., Keller, Lindsay P., Khodja, H., Kilcoyne, A. L. David, Kissel, Jochen, Krot, Alexander, Langenhorst, Falko, Lanzirotti, Antonio, Le, Loan, Leshin, Laurie A., Leitner, J., Lemelle, L., Leroux, Hugues, Liu, Ming-Chang, Leuning, K., Lyon, Ian, MacPherson, Glen, Marcus, Matthew A., Marhas, Kuljeet, Marty, Bernard, Matrajt, Graciela, McKeegan, Kevin, Meibom, Anders, Mennella, Vito, Messenger, Keiko, Messenger, Scott, Mikouchi, Takeshi, Mostefaoui, Smail, Nakamura, Tomoki, Nakano, T., Newville, M., Nittler, Larry R., Ohnishi, Ichiro, Ohsumi, Kazumasa, Okudaira, Kyoko, Papanastassiou, Dimitri A., Palma, Russ, Palumbo, Maria E., Pepin, Robert O., Perkins, David, Perronnet, Murielle, Pianetta, P., Rao, William, Rietmeijer, Frans J. M., Robert, François, Rost, D., Rotundi, Alessandra, Ryan, Robert, Sandford, Scott A., Schwandt, Craig S., See, Thomas H., Schlutter, Dennis, Sheffield-Parker, J., Simionovici, Alexandre, Simon, Steven, Sitnitsky, I., Snead, Christopher J., Spencer, Maegan K., Stadermann, Frank J., Steele, Andrew, Stephan, Thomas, Stroud, Rhonda, Susini, Jean, Sutton, S. R., Suzuki, Y., Taheri, Mitra, Taylor, Susan, Teslich, Nick, Tomeoka, Kazu, Tomioka, Naotaka, Toppani, Alice, Trigo-Rodríguez, Josep M., Troadec, David, Tsuchiyama, Akira, Tuzzolino, Anthony J., Tyliszczak, Tolek, Uesugi, K., Velbel, Michael, Vellenga, Joe, Vicenzi, E., Vincze, L., Warren, Jack, Weber, Iris, Weisberg, Mike, Westphal, Andrew J., Wirick, Sue, Wooden, Diane, Wopenka, Brigitte, Wozniakiewicz, Penelope, Wright, Ian, Yabuta, Hikaru, Yano, Hajime, Young, Edward D., Zare, Richard N., Zega, Thomas, Ziegler, Karen, Zimmerman, Laurent, Zinner, Ernst, and Zolensky, Michael

Published
2006
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37. Isotopic Compositions of Cometary Matter Returned by Stardust

Author

McKeegan, Kevin D., Aléon, Jerome, Bradley, John, Brownlee, Donald, Busemann, Henner, Butterworth, Anna, Chaussidon, Marc, Fallon, Stewart, Floss, Christine, Gilmour, Jamie, Gounelle, Matthieu, Graham, Giles, Guan, Yunbin, Heck, Philipp R., Hoppe, Peter, Hutcheon, Ian D., Huth, Joachim, Ishii, Hope, Ito, Motoo, Jacobsen, Stein B., Kearsley, Anton, Leshin, Laurie A., Liu, Ming-Chang, Lyon, Ian, Marhas, Kuljeet, Marty, Bernard, Matrajt, Graciela, Meibom, Anders, Messenger, Scott, Mostefaoui, Smail, Mukhopadhyay, Sujoy, Nakamura-Messenger, Keiko, Nittler, Larry, Palma, Russ, Pepin, Robert O., Papanastassiou, Dimitri A., Robert, François, Schlutter, Dennis, Snead, Christopher J., Stadermann, Frank J., Stroud, Rhonda, Tsou, Peter, Westphal, Andrew, Young, Edward D., Ziegler, Karen, Zimmermann, Laurent, and Zinner, Ernst

Published
2006
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38. Mineralogy and Petrology of Comet 81p/Wild 2 Nucleus Samples

Author

Zolensky, Michael E., Zega, Thomas J., Yano, Hajime, Wirick, Sue, Westphal, Andrew J., Weisberg, Mike K., Weber, Iris, Warren, Jack L., Velbel, Michael A., Tsuchiyama, Akira, Tsou, Peter, Toppani, Alice, Tomioka, Naotaka, Tomeoka, Kazushige, Teslich, Nick, Taheri, Mitra, Susini, Jean, Stroud, Rhonda, Stephan, Thomas, Stadermann, Frank J., Snead, Christopher J., Simon, Steven B., Simionovici, Alexandre, See, Thomas H., Robert, François, Rietmeijer, Frans J. M., Rao, William, Perronnet, Murielle C., Papanastassiou, Dimitri A., Okudaira, Kyoko, Ohsumi, Kazumasa, Ohnishi, Ichiro, Nakamura-Messenger, Keiko, Nakamura, Tomoki, Mostefaoui, Smail, Mikouchi, Takashi, Meibom, Anders, Matrajt, Graciela, Marcus, Matthew A., Leroux, Hugues, Lemelle, Laurence, Le, Loan, Lanzirotti, Antonio, Langenhorst, Falko, Krot, Alexander N., Keller, Lindsay P., Kearsley, Anton T., Joswiak, David, Jacob, Damien, Ishii, Hope, Harvey, Ralph, Hagiya, Kenji, Grossman, Lawrence, Grossman, Jeffrey N., Graham, Giles A., Gounelle, Matthieu, Gillet, Philippe, Genge, Matthew J., Flynn, George, Ferroir, Tristan, Fallon, Stewart, Ebel, Denton S., Dai, Zu Rong, Cordier, Patrick, Clark, Benton, Chi, Miaofang, Butterworth, Anna L., Brownlee, Donald E., Bridges, John C., Brennan, Sean, Brearley, Adrian, Bradley, John P., Bleuet, Pierre, Bland, Phil A., and Bastien, Ron

Published
2006
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39. Organics Captured from Comet 81p/Wild 2 by the Stardust Spacecraft

Author

Sandford, Scott A., Aléon, Jérôme, Alexander, Conel M. O'D., Araki, Tohru, Bajt, Saša, Baratta, Giuseppe A., Borg, Janet, Bradley, John P., Brownlee, Donald E., Brucato, John R., Burchell, Mark J., Busemann, Henner, Butterworth, Anna, Clemett, Simon J., Cody, George, Colangeli, Luigi, Cooper, George, D'Hendecourt, Louis, Djouadi, Zahia, Dworkin, Jason P., Ferrini, Gianluca, Fleckenstein, Holger, Flynn, George J., Franchi, Ian A., Fries, Marc, Gilles, Mary K., Glavin, Daniel P., Gounelle, Matthieu, Grossemy, Faustine, Jacobsen, Chris, Keller, Lindsay P., Kilcoyne, A. L. David, Leitner, Jan, Matrajt, Graciela, Meibom, Anders, Mennella, Vito, Mostefaoui, Smail, Nittler, Larry R., Palumbo, Maria E., Papanastassiou, Dimitri A., Robert, François, Rotundi, Alessandra, Snead, Christopher J., Spencer, Maegan K., Stadermann, Frank J., Steele, Andrew, Stephan, Thomas, Tsou, Peter, Tyliszczak, Tolek, Westphal, Andrew J., Wirick, Sue, Wopenka, Brigitte, Yabuta, Hikaru, Zare, Richard N., and Zolensky, Michael E.

Published
2006
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40. (Contents to) Atlas general, civil, ecclesiastique et militaire, methodique et elementaire pour l'etude de la geographie et de l'histoire : ouvrage destine specialement a l'instruction de la jeune noblesse de l'Ecole royale militaire : adapte aux livres de geographie les plus suivis, entr'autres a ceux de M.M. l'abbe Langlet du Frenoy, Robert profr. de philphie., celle dediee a Mle. Crozat, et particulierement pour l'abbe Nicole de La Croix. Et a la Nouvle. methode geographique de Mr. l'abbe Compan, dediee a Madame de France; dresse d'apres les nouvelles observations astronomiques faites par M.M. Thirikcow [i.e. Tchirikov] et de l'Isle, par M. Brion, dirige par le sr. Desnos … A Paris 1786. Tous les livres cite es ici se trouvent chez Desnos.

Author

Brion de La Tour, Louis, 1743 – 1803, Desnos, Louis Charles, Desnos, Louis-Charles, Chirikov, Aleksei, 1703-1748., L'Isle de la Croyère, Louis., Robert, François, 1737-1819, Nicolle de La Croix, abbe, 1704-1760, Rizzi-Zannoni, Giovanni Antonio, 1736-1814, Chambon, and Croisey, Jean-Baptiste

Subjects
Paris
Abstract

3rd edition, with double-page maps engraved on copper, ornate title page, an alphabetical index of the countries and cities, 55 maps listed in the table of maps, 3 unnumbered maps, and 2 sheets of plate 12-13, and plate 27-28. Maps are double page and 1 folded, engraved hand colored, in a Louis XV frame, with ornamental title cartouche. This atlas adds two other maps titled "Nouvelle Carte de la Parue Des Indes Orientales, qui comprend entr'autres Etats, les vastres Possessions des Anglais" New map of the East Indies part, which includes the English possessions, and "Carte Des Etats-Unis de l'Amerique Septen trionale, dressee d'apres des Cartes Anglaises", Map of the United States of North America, being a close up of the newly formed United States, drawn up from English maps. Hand written dates and inscriptions in French on both inside the front and back covers, describing the acquisition of this book in 1803 by someone serving under the French imperial command. Bound in dark brown calf with brown marbled boards, embossed gilt designs on spine with title "Atlas General".

Published
1786

41. (Text Page to) Atlas general, civil, ecclesiastique et militaire, methodique et elementaire pour l'etude de la geographie et de l'histoire : ouvrage destine specialement a l'instruction de la jeune noblesse de l'Ecole royale militaire : adapte aux livres de geographie les plus suivis, entr'autres a ceux de M.M. l'abbe Langlet du Frenoy, Robert profr. de philphie., celle dediee a Mle. Crozat, et particulierement pour l'abbe Nicole de La Croix. Et a la Nouvle. methode geographique de Mr. l'abbe Compan, dediee a Madame de France; dresse d'apres les nouvelles observations astronomiques faites par M.M. Thirikcow [i.e. Tchirikov] et de l'Isle, par M. Brion, dirige par le sr. Desnos … A Paris 1786. Tous les livres cite es ici se trouvent chez Desnos.

Author

Brion de La Tour, Louis, 1743 – 1803, Desnos, Louis Charles, Desnos, Louis-Charles, Chirikov, Aleksei, 1703-1748., L'Isle de la Croyère, Louis., Robert, François, 1737-1819, Nicolle de La Croix, abbe, 1704-1760, Rizzi-Zannoni, Giovanni Antonio, 1736-1814, Chambon, and Croisey, Jean-Baptiste

Subjects
Paris
Abstract

3rd edition, with double-page maps engraved on copper, ornate title page, an alphabetical index of the countries and cities, 55 maps listed in the table of maps, 3 unnumbered maps, and 2 sheets of plate 12-13, and plate 27-28. Maps are double page and 1 folded, engraved hand colored, in a Louis XV frame, with ornamental title cartouche. This atlas adds two other maps titled "Nouvelle Carte de la Parue Des Indes Orientales, qui comprend entr'autres Etats, les vastres Possessions des Anglais" New map of the East Indies part, which includes the English possessions, and "Carte Des Etats-Unis de l'Amerique Septen trionale, dressee d'apres des Cartes Anglaises", Map of the United States of North America, being a close up of the newly formed United States, drawn up from English maps. Hand written dates and inscriptions in French on both inside the front and back covers, describing the acquisition of this book in 1803 by someone serving under the French imperial command. Bound in dark brown calf with brown marbled boards, embossed gilt designs on spine with title "Atlas General".

Published
1786

42. (Composite Text to) Atlas general, civil, ecclesiastique et militaire, methodique et elementaire pour l'etude de la geographie et de l'histoire : ouvrage destine specialement a l'instruction de la jeune noblesse de l'Ecole royale militaire : adapte aux livres de geographie les plus suivis, entr'autres a ceux de M.M. l'abbe Langlet du Frenoy, Robert profr. de philphie., celle dediee a Mle. Crozat, et particulierement pour l'abbe Nicole de La Croix. Et a la Nouvle. methode geographique de Mr. l'abbe Compan, dediee a Madame de France; dresse d'apres les nouvelles observations astronomiques faites par M.M. Thirikcow [i.e. Tchirikov] et de l'Isle, par M. Brion, dirige par le sr. Desnos … A Paris 1786. Tous les livres cite es ici se trouvent chez Desnos.

Author

Brion de La Tour, Louis, 1743 – 1803, Desnos, Louis Charles, Desnos, Louis-Charles, Chirikov, Aleksei, 1703-1748., L'Isle de la Croyère, Louis., Robert, François, 1737-1819, Nicolle de La Croix, abbe, 1704-1760, Rizzi-Zannoni, Giovanni Antonio, 1736-1814, Croisey, Jean-Baptiste, and Chambon

Subjects
Paris
Abstract

3rd edition, with double-page maps engraved on copper, ornate title page, an alphabetical index of the countries and cities, 55 maps listed in the table of maps, 3 unnumbered maps, and 2 sheets of plate 12-13, and plate 27-28. Maps are double page and 1 folded, engraved hand colored, in a Louis XV frame, with ornamental title cartouche. This atlas adds two other maps titled "Nouvelle Carte de la Parue Des Indes Orientales, qui comprend entr'autres Etats, les vastres Possessions des Anglais" New map of the East Indies part, which includes the English possessions, and "Carte Des Etats-Unis de l'Amerique Septen trionale, dressee d'apres des Cartes Anglaises", Map of the United States of North America, being a close up of the newly formed United States, drawn up from English maps. Hand written dates and inscriptions in French on both inside the front and back covers, describing the acquisition of this book in 1803 by someone serving under the French imperial command. Bound in dark brown calf with brown marbled boards, embossed gilt designs on spine with title "Atlas General".

Published
1786

43. From structure to molecular condensates: emerging mechanisms for Mediator function.

Author

Lambert, Élie, Puwakdandawa, Kavindu, Tao, Yi Fei, and Robert, François

Subjects
MOLECULAR structure, GENETIC regulation, NUCLEAR receptors (Biochemistry), PHASE separation, CHROMATIN
Abstract

Mediator is a large modular protein assembly whose function as a coactivator of transcription is conserved in all eukaryotes. The Mediator complex can integrate and relay signals from gene‐specific activators bound at enhancers to activate the general transcription machinery located at promoters. It has thus been described as a bridge between these elements during initiation of transcription. Here, we review recent studies on Mediator relating to its structure, gene specificity and general requirement, roles in chromatin architecture as well as novel concepts involving phase separation and transcriptional bursting. We revisit the mechanism of action of Mediator and ultimately put forward models for its mode of action in gene activation. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
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44. L'immeuble de rapport : L'immobilier entre gestion et spéculation (Lyon 1860-1990)

Author

Robert, François, Bonneval, Loïc, Robert, François, Robert, François, Bonneval, Loïc, and Robert, François

Abstract

L’immeuble de rapport est la forme urbaine dominante en France au XIXe siècle et dans la première moitié du XXe siècle. Il incarne, surtout à partir des années 1850, une organisation dans laquelle la propriété occupante est très minoritaire. La plupart des habitants sont locataires dans des immeubles détenus par des propriétaires rentiers. Les historiens ont déjà abordé ce thème, pourtant, nombre de ses facettes restent méconnues, comme les motivations de l’investissement dans la pierre, les rôles respectifs des logiques économiques et familiales, notamment à l’occasion des successions, ou encore les raisons du passage à la copropriété. Le présent ouvrage cherche à les explorer en s’appuyant sur une source rare, les archives de comptabilité d’immeubles d’un administrateur de biens. Elles permettent, après des traitements spécifiques, complétés par des sources publiques, d’éclairer les logiques économiques et les rapports sociaux qui se nouent autour des immeubles à loyers, en accordant une place centrale à la question de la rentabilité du placement dans la pierre et de ses effets. L’étude couvre une longue période, de « l’âge d’or » de l’immeuble de rapport dans le dernier quart du XIXe siècle à l’amorce de son déclin durant l’entre-deux-guerres. Les analyses que les auteurs proposent ici rencontrent les préoccupations actuelles des politiques du logement et s’inscrivent plus largement dans la recherche sur les phénomènes immobiliers.

Published
2019

48. NEWSLETTER: UNESCO INTERNATIONAL TEXTBOOK RESEARCH NETWORK 8

Author

Henrÿ, Roderich, Quillévéré, Isabelle, Hecht, Alfred, Pletsch, Alfred, Tutiaux-Guillon, Nicole, Robert, François, Fontanabona, Jacky, Pénisson, Michel, Compan, Gérard, Micola, Lionel, and Cazorla, Bernard

Published
1999

50. Ludovic Frobert et George Sheridan, Le solitaire du ravin. Pierre Charnier (1795-1857), canut lyonnais et prud’homme tisseur

Author

Robert, François

Abstract

Ce livre s’insère dans la lignée des travaux sur le thème de la régulation et de la naissance des corps intermédiaires menés depuis les années 1990. La publication d’une biographie d’un des acteurs privilégiés de l’émergence d’un système régulé, la Fabrique lyonnaise, nous plonge au cœur des débats qui ont fait rage dans la première moitié du xixe siècle. L’histoire des papiers de Pierre Charnier, découverts chez un libraire au début des années 1930 par l’historien lyonnais Fernand Rude (1910...

Published
2021

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