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2. Health hazards related to using masks and/or personal protective equipment among physicians working in public hospitals in Dhaka: A cross-sectional study

Author

Mahmud, Reaz, primary, Joy, K. M. Nazmul Islam, additional, Rassel, Mohammad Aftab, additional, Monayem, Farhana Binte, additional, Datta, Ponkaj Kanti, additional, Hossain, Mohammad Sharif, additional, Hoque, Mohammad Mahfuzul, additional, Habib, S. M. Habibur Rahman, additional, Munna, Nazmul Hoque, additional, Ahmed, Mohiuddin, additional, Sayeed, S. K. Jakaria Been, additional, Rahman, Motlabur, additional, Chowdhury, Ahmed Hossain, additional, Hossain, Mohammad Zaid, additional, Ahmed, Kazi Gias Uddin, additional, Miah, Md. Titu, additional, and Rahman, Md. Mujibur, additional

Published
2022
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3. Prevalence and Outcome of Cardio-Embolic Stroke Patients Admitted at Referral Neurology Hospital in Bangladesh

Author

Been Sayeed, S K Jakaria, primary, Haque, AKM Mahmudul, additional, Moniruzzaman, Md., additional, Mahmud, Reaz, additional, Chandra Das, Subir, additional, Bazlur Rashid, Mohammad, additional, Rahman, Sabrina, additional, Mostafa, Golam, additional, Nayeem, Abu, additional, Hoque Chowdhury, MS Jahirul, additional, and Rahman, Md. Mujibur, additional

Published
2022
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5. Association of ABO blood groups with presentation and outcomes of confirmed SARS CoV-2 infection: A prospective study in the largest COVID-19 dedicated hospital in Bangladesh

Author

Mahmud, Reaz, primary, Rassel, Mohammad Aftab, additional, Monayem, Farhana Binte, additional, Sayeed, S. K. Jakaria Been, additional, Islam, Md Shahidul, additional, Islam, Mohammed Monirul, additional, Yusuf, Mohammad Abdullah, additional, Rahman, Sabrina, additional, Islam, K. M. Nazmul, additional, Mahmud, Imran, additional, Hossain, Mohammad Zaid, additional, Chowdhury, Ahmed Hossain, additional, Kabir, A. K. M. Humayon, additional, Ahmed, Kazi Gias Uddin, additional, and Rahman, Md. Mujibur, additional

Published
2021
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6. Clinical and laboratory characteristics and outcome predictors of cerebral venous sinus thrombosis in a referral neurology hospital in Bangladesh

Author

Moniruzzaman, Md., Been Sayeed, S K Jakaria, Das, Subir Chandra, Mostafa, Md. Golam, Rashid, Md. Bazlur, Mahmud, Reaz, Akhter, Muntrasina, Mehzabin, Refat, Hossain, Sk. Md. Rubaed, and Rahman, Md. Mujibur

Abstract

Objective We aimed to describe clinical and laboratory characteristics and determine the predictors of outcome in patients with cerebral venous sinus thrombosis.Methods This prospective study was conducted over 2 years among hospitalized patients with cerebral venous sinus thrombosis. Patient outcome was assessed using the Modified Rankin Scale (mRS) score at 3 months. Outcome predictors were identified using logistic regression analysis.Results Eighty-one patients were included in this study. The median mRS outcome at 3 months was 1 (interquartile range 1–3). Poor outcomes were observed in 27.2% of patients, and the mortality rate was 9.8%. Factors associated with poor outcomes were age >60 years (relative risk [RR] 5.1), hemiparesis (RR 5.4), altered level of consciousness (RR 7.1), and transverse sinus involvement (RR 1.1). In general, mRS scores were not associated with D-dimer levels (RR 2.4). However, older patients with elevated D-dimer levels showed a significant association with poor outcomes (1.6) according to mRS scores.Conclusion Older age, hemiparesis, and altered consciousness levels were independent predictors of poor outcomes in patients with cerebral venous sinus thrombosis. High D-dimer level showed no association with functional disability, except in older patients.

Published
2024
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7. Ivermectin in combination with doxycycline for treating COVID-19 symptoms: a randomized trial.

Author

Mahmud R, Rahman MM, Alam I, Ahmed KGU, Kabir AKMH, Sayeed SKJB, Rassel MA, Monayem FB, Islam MS, Islam MM, Barshan AD, Hoque MM, Mallik MU, Yusuf MA, and Hossain MZ

Subjects
Adult, Doxycycline therapeutic use, Female, Humans, Male, SARS-CoV-2, Treatment Outcome, COVID-19, Ivermectin therapeutic use
Abstract

Objective: We evaluated whether ivermectin combined with doxycycline reduced the clinical recovery time in adults with COVID-19 infection., Methods: This was a randomized, blinded, placebo-controlled trial in patients with mild-to-moderate COVID-19 symptoms randomly assigned to treatment (n = 200) and placebo (n = 200) groups. The primary outcome was duration from treatment to clinical recovery. Secondary outcomes were disease progression and persistent COVID-19 positivity by RT-PCR., Results: Among 556 screened patients, 400 were enrolled and 363 completed follow-up. The mean patient age was 40 years, and 59% were men. The median recovery time was 7 (4-10, treatment group) and 9 (5-12, placebo group) days (hazard ratio, 0.73; 95% confidence interval, 0.60-0.90). The number of patients with a ≤7-day recovery was 61% (treatment group) and 44% (placebo groups) (hazard ratio, 0.06; 95% confidence interval, 0.04-0.09). The proportion of patients who remained RT-PCR positive on day 14 and whose disease did not progress was significantly lower in the treatment group than in the placebo group., Conclusions: Patients with mild-to-moderate COVID-19 infection treated with ivermectin plus doxycycline recovered earlier, were less likely to progress to more serious disease, and were more likely to be COVID-19 negative by RT-PCR on day 14., Trial Registration: ClinicalTrials.gov Identifier: NCT04523831., Data Repository Id: Dryad. doi:10.5061/dryad.qjq2bvqf6.

Published
2021
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