197 results on '"Schäfer, Reinhold"'
Search Results
2. RNA sequencing of long-term label-retaining colon cancer stem cells identifies novel regulators of quiescence
3. A combined computational and functional approach identifies IGF2BP2 as a driver of chemoresistance in a wide array of pre-clinical models of colorectal cancer
4. Editorial: Hallmark of cancer: Evasion of growth suppressors
5. Reduced replication origin licensing selectively kills KRAS-mutant colorectal cancer cells via mitotic catastrophe
6. VIST - a Variant-Information Search Tool for precision oncology
7. Assay Establishment and Validation of a High-Throughput Screening Platform for Three-Dimensional Patient-Derived Colon Cancer Organoid Cultures
8. Growth-Inhibitory Activity and Downregulation of the Class II Tumor-Suppressor Gene H-rev107 in Tumor Cell Lines and Experimental Tumors
9. A primary undifferentiated pleomorphic sarcoma of the lumbosacral region harboring a LMNA-NTRK1 gene fusion with durable clinical response to crizotinib: a case report
10. Serial Analysis of Gene Mutations and Gene Expression during First-Line Chemotherapy against Metastatic Colorectal Cancer: Identification of Potentially Actionable Targets within the Multicenter Prospective Biomarker Study REVEAL
11. IC50: an unsuitable measure for large-sized prostate cancer spheroids in drug sensitivity evaluation
12. Evaluation of JQ1 Combined With Docetaxel for the Treatment of Prostate Cancer Cells in 2D- and 3D-Culture Systems
13. Expression of the Murine Small Heat Shock Proteins hsp 25 and αB Crystallin in the Absence of Stress
14. Partial Reversion of the Transformed Phenotype in HRAS-Transfected Tumorigenic Cells by Transfer of a Human Gene
15. Molecular and Functional Analysis of Tumor-Suppressor Genes by Transfection
16. IC50: an unsuitable measure for large-sized prostate cancer spheroids in drug sensitivity evaluation.
17. Prediction of doxorubicin sensitivity in breast tumors based on gene expression profiles of drug-resistant cell lines correlates with patient survival
18. Transcriptional basis of KRAS oncogene-mediated cellular transformation in ovarian epithelial cells
19. SFPQ Depletion Is Synthetically Lethal with BRAFV600E in Colorectal Cancer Cells
20. The class II tumour suppressor gene H-REV107-1 is a target of interferon-regulatory factor-1 and is involved in IFNγ-induced cell death in human ovarian carcinoma cells
21. Gene expression profiling of fibroblasts resistant toward oncogene-mediated transformation reveals preferential transcription of negative growth regulators
22. Transcriptional and translational downregulation of H-REV107, a class II tumour suppressor gene located on human chromosome 11q11-12
23. A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts
24. Discovery and Validation of Novel Biomarkers for Detection of Epithelial Ovarian Cancer
25. HuSiDa—the human siRNA database: an open-access database for published functional siRNA sequences and technical details of efficient transfer into recipient cells
26. Nitric oxide mediates apoptosis induction selectively in transformed fibroblasts compared to nontransformed fibroblasts
27. ras oncogene expression determines sensitivity for intercellular induction of apoptosis
28. Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures
29. Characterization of AKT independent effects of the synthetic AKT inhibitors SH-5 and SH-6 using an integrated approach combining transcriptomic profiling and signaling pathway perturbations
30. Spectro ML-A Markup Language for Molecular Spectrometry Data
31. Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells
32. Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors
33. DNA copy number changes define spatial patterns of heterogeneity in colorectal cancer
34. Y-box protein-1/p18 as novel serum marker for ovarian cancer diagnosis: A study by the Tumor Bank Ovarian Cancer (TOC)
35. Effects of RAL signal transduction in KRAS- and BRAF-mutated cells and prognostic potential of the RAL signature in colorectal cancer
36. Abstract PR06: Impact of RAL signal transduction on genetic program and growth control in KRAS- and BRAF-mutated colorectal cells and prognostic potential of pathway-responsive genes in cancer patients
37. Abstract 5170: Linking tumor evolution and therapy response using diagnostic targeted next generation sequencing in colorectal cancer
38. Ras-Mediated Deregulation of the Circadian Clock in Cancer
39. The Nerve Growth Factor Receptor CD271 Is Crucial to Maintain Tumorigenicity and Stem-Like Properties of Melanoma Cells
40. Identifying Resistance Mechanisms against Five Tyrosine Kinase Inhibitors Targeting the ERBB/RAS Pathway in 45 Cancer Cell Lines
41. Network quantification of EGFR signaling unveils potential for targeted combination therapy
42. Reverse engineering a hierarchical regulatory network downstream of oncogenic KRAS
43. Identification of Y-Box Binding Protein 1 As a Core Regulator of MEK/ERK Pathway-Dependent Gene Signatures in Colorectal Cancer Cells
44. Characterization of AKT independent effects of the synthetic AKT inhibitors SH-5 and SH-6 using an integrated approach combining transcriptomic profiling and signaling pathway perturbations
45. Atypical Protein Kinase C ζ Exhibits a Proapoptotic Function in Ovarian Cancer
46. Systems Biologists Seek Fuller Integration of Systems Biology Approaches in New Cancer Research Programs
47. “It's Not Hard to Make Decisions When You Know What Your Values Are”
48. Connecting Communities and Creating Opportunities
49. ALA Welcomes a New Generation of Lab Automation Leaders
50. Visualize Whirled Peas
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