98 results on '"Scherr, J."'
Search Results
2. Training, Competition & Health
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Steinacker JM, Schellenberg J, Bloch W, Deibert P, Friedmann-Bette B, Grim C, Halle M, Hirschmüller A, Hollander K, Kerling A, Kopp C, Mayer F, Meyer T, Niebauer J, Predel HG, Reinsberger C, Röcker K, Scharhag J, Scherr J, Schmidt-Trucksäss A, Schneider C, Schobersberger W, Weisser B, Wolfarth B, and Nieß AM
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Sports medicine ,RC1200-1245 - Abstract
Introduction: An infection with SARS-CoV-2 is relevant especially in high-performance sport due to possible organ damage and reduced performance which occurs in individual cases. Various recommendations are found in the literature concerning when safe return to sports is possible and what examinations are suitable to support this decision. The dominance of other virus variants than those at the start of the pandemic makes revision of earlier recommendations necessary. Methods and Analysis: The recommended actions are based on the currently-available scientific knowledge of the pathogenicity of the virus and on clinical experiences in general and elite athletes. Twenty-one recommended actions were proposed by the Scientific Council of the DGSP, discussed and agreed on in consensus with experts from German-language sports-medical facilities and evaluated by an independent co-author. The resultant position paper was subsequently released by mutual agreement. Results: The recommendations are oriented to the severity of the course and the symptoms. The required medical diagnostic is deduced therefrom. During persistent symptoms, sports should be paused and training only begun again at low intensity after a three-day symptom-free period. If COVID-19-associated complaints recur, physical exertion should be stopped and a doctor consulted. After moderate and serious course, medical diagnostics are required prior to the start of training. Summary: To prevent a health risk due to sports and thereby resultant organ damage after a SARS-CoV-2 infection, a procedure adapted to the symptoms and course before return to training and finally to competitive sports is recommended.
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- 2022
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3. Psychiatry and Sports Medicine
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Claussen MC, Gonzalez Hofmann C, Schneeberger AR, Seifritz E, Schorb A, Allroggen M, Freyer T, Helmig F, Niebauer J, Hefert J, Klostermeier E, Fröhlich S, and Scherr J
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Sports medicine ,RC1200-1245 - Abstract
Mental stress and illness are common health problems in competitive sports that can reduce performance and have effects beyond the end of a career as sport-specific and unspecific disorders.The promotion of mental health and safe handling of mental problems and illnesses require appropriate education and train-ing. However, child, adolescent and adult psychiatrists with specific expertise in competitive sports (sports psychiatrists) are not yet an integral part of the structure of medical care provision in competitive sports.This position paper gives an overview about existing care structures in competitive sports for the promotion of mental health, and investigated them with proposals for the further development of sports psychiatric care in competitive sports. Sports physicians, sports psychiatrists, as well as interdisci- plinary and interprofessional collaboration, are at the center of mental health efforts in competitive sports.Further aspects that will be discussed are the education and training of athletes and the environment in competitive sports, as well as the promotion of coaches health.Key Words: Elite sports, Prevention, Mental health problems and disorders, Sports psychiatry, Sports Medicine
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- 2021
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4. Psychiatric and Sports Medicine
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Gonzalez Hofmann C, Wyssen A, Schorb A, Allroggen M, Dallmann P, Schmidt RE, Graffius S-T, Niebauer J, Herfert J, Fröhlich S, Scherr J, and Claussen MC
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Sports medicine ,RC1200-1245 - Abstract
Pre-Participation Examination (PPE) is recommended in many countries prior to or during the practice of competitive sports. The dedicated exploration of psychological complaints and illnesses in the sense of a psychiatric basic assessment within the PPE is not yet the rule. The implementation of a Psychiatric Basic Assessment (PBA) in the PPE is proposed and presented in terms of content. Abnormal findings in the PBA, crises, emergencies as well as conspicuous changes in behaviour should lead to further sports psychiatric evaluation (SPE) by child, adolescent and adult psychiatrists and psychotherapists qualified for this purpose.The goal is to use diagnostic and procedural standards to identify risks to mental health, stress, and already manifest illnesses in a timely manner and to provide qualified, specialized medical or psychiatric treatment. The diagnostic standards are intended to promote research and the benefits are to be verified by studies.Key Words: Psychiatric Basic Assessment (PBA), Sports Psychiatric Evaluation (SPE), Mental Health, Mental Disorders, Pre-Participation Examination (PPE)
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- 2021
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5. Psychiatry and Sports Medicine
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Scherr J and Claussen MC
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Sports medicine ,RC1200-1245 - Published
- 2021
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6. Psychiatry and Sports Medicine
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Schorb A, Niebauer J, Aichhorn W, Schiepek G, Scherr J, and Claussen MC
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Sports medicine ,RC1200-1245 - Abstract
Overtraining is characterized by a mismatch between exerted strain and exercise tolerance. Overtraining is generally not sufficiently feared nor is enough attention paid to its prevention. As a result, the first warning signals and symptoms are often either perceived too late or there is a delay in the correct interpretation of signs. This often leads to negative consequences over months, which, in turn, can lead to more frequent injuries as well as Depression. Due to the increasing professionalism and density of competition in competitive sports, overtraining occurs more frequently as athletes are left with a shorter period of time to recover. In order to treat overtraining, it is first necessary to identify the syndrome. Symptoms are often disregarded and trainers and athletes attempt to compensate for poor performance with excessive training. This leads to a vicious cycle with significant reduction of the overall performance of the athlete as a consequence. Psychological parameters can also be signs of non-func-tional overload. Examples include restlessness, irritability, emotional instability, recurring states of fear, emerging indifference or reduced performance motivation. However, disturbed cognitive processes as an impairment of central elements of movement control can also occur. As part of sports psychiatric support, conspicuous psychological parameters can be recorded and contextualised. The Synergetic Navigation System (SNS) is available for systematic recording and corresponding process management. The Synergetic Navigation System (SNS) can be used as an instrument for load, training and competition control to prevent non-functional overload and overtraining. It is also suitable for promoting performance and preventing injuries as well as stabilizing the psychological structure.Key Words:Mental Health Symptoms, Mental Disorders, Injury Prevention, Exercise Intolerance, Synergetic Navigation System (SNS)
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- 2021
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7. Psychiatry and Sports Medicine
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Gerber M, Claussen MC, Cody R, Imboden C, Ludyga S, Scherr J, Seifritz E, and von Känel R
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Sports medicine ,RC1200-1245 - Abstract
Problem: Depression is a widespread disorder and among the leading causes of disability worldwide. In this article, we perform an umbrella review on the association between depression and excess mortality, cardiovascular disease (CVD), and cardiovascular risk factors. We also provide an overview of mechanisms that explain these associations. Finally, we discuss clinical implications from a general perspective and discuss the potential of physical activity to favorably influence the relationship between depression and premature mortality.Methods: Meta-analyses were identified via PubMed. Only works on unipolar depression were included.Results: The association between depression and excess mortality is a robust epidemiological finding. This association can be attributed to the fact that people with depression are at increased risk for CVD and accumulate more cardiovascular risk factors. However, the causal associations are complex. While depression is associated with incident CVD, depression can also be a consequence of cardiac events. Regular physical activity and higher cardiorespiratory fitness levels mitigate the risk of premature mortality associated with depression.Discussion: More attention should be paid to the physical health of psychiatric patients. High priority should be given to the promotion of physical activity and fitness, as they are beneficial for both physical and mental health.Key Words: Fitness, Cardiovascular Disease, Physical Activity, Mortality
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- 2021
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8. [Untitled]
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Claussen MC, Fröhlich S, Spörri J, Hasan A, Seifritz E, Scherr J, and Markser VZ
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Sports medicine ,RC1200-1245 - Published
- 2020
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9. [Untitled]
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Claussen MC, Fröhlich S, Spörri J, Seifritz E, Markser VZ, and Scherr J
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Sports medicine ,RC1200-1245 - Published
- 2020
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10. [Untitled]
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Nieß AM, Bloch W, Friedmann-Bette B, Grim C, Gärtner B, Halle M, Hirschmüller A, Kopp C, Meyer T, Niebauer J, Predel G, Reinsberger C, Röcker K, Scharhag J, Schneider C, Scherr J, Steinacker JM, Mayer F, and Wolfarth B
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Sports medicine ,RC1200-1245 - Published
- 2020
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11. [Untitled]
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Nieß AM, Bloch W, Friedmann-Bette B, Grim C, Halle M, Hirschmüller A, Kopp C, Meyer T, Niebauer J, Reinsberger C, Röcker K, Scharhag J, Scherr J, Schneider C, Steinacker JM, Urhausen A, Wolfarth B, and Mayer F
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Sports medicine ,RC1200-1245 - Published
- 2020
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12. Clinical Sports Medicine
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Steinacker JM, Bloch W, Halle M, Mayer F, Meyer T, Hirschmüller A, Röcker K, Nieß A, Scharhag J, Reinsberger C, Scherr J, Niebauer J, and Wolfarth B and Sports Medicine Commission of FISA
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Sports medicine ,RC1200-1245 - Published
- 2020
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13. Fitness & Sports Medicine
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Lechner K, Lechner B, Engel H, Halle M, Worm N, and Scherr J
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Sports medicine ,RC1200-1245 - Abstract
Vitamin D (VitD) and its physiological function in regulating calcium/phosphorus absorption and bone remineralization werefirst described in the early 20thcentury. A better understanding of VitD signaling has advanced our understanding of the importance of adequate VitD status to human health and performance. Tissues relevant to athletes which depend on VitD for optimal function include innate and adaptive immune system, skeletal muscle, and bone. Cross-sectional studies have shown that more than half of athletes are deficient and/or insufficient in VitD. Correcting insufficiency, the suggested target of25(OH)D blood levels above 30 ng/ml has the potential to optimize various aspects related to performance and regeneration in VitD insufficient athletes. This might help athletes to reach their full potential. Of note, there is no evidence pointing to actual or potential health risks of VitD levels within the recommended limits. VitD is therefore not on the list of prohibited substances of the world anti-doping agency.To avoid toxicity, VitD status should be monitored and supplementation strategies should be individualized and target-oriented. In terms of effectiveness and safety, low-dosed, continuous supplementation strategies of VitD are superior to intermittent application of supraphysiological boluses. The concept of synergy between nutrients lends qualified support tothe assumption that VitD bioavailability and function depend on meal context and onthefat-soluble vitamins A and K2 as well as the minerals magnesium and zinc. KEY WORDS: Regeneration, Immune System, Muscular Function, Bone Health, Supplementation Strategies
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- 2020
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14. Trans fatty acid blood levels and HFpEF phenotype: from the Aldo-DHF RCT
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Bock, M, primary, Von Schacky, C, additional, Scherr, J, additional, Lorenz, E, additional, Lechner, B, additional, Haller, B, additional, Krannich, A, additional, Halle, M, additional, Wachter, R, additional, Duvinage, A, additional, Edelmann, F, additional, and Lechner, K, additional
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- 2022
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15. Influence of high polyphenol beverage on stress-induced platelet activation
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Nickel, Thomas, Lackermair, K., Scherr, J., Calatzis, A., Vogeser, M., Hanssen, H., Waidhauser, G., Schönermark, U., Methe, H., Horster, S., Wilbert-Lampen, U., and Halle, M.
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- 2016
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16. Die Makulatur des Kreises?: ereignisoffene Geschichte bei Polybius
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Scherr, Jonas, Gronau, Martin, Saracino, Stefano, Scherr, J ( Jonas ), Gronau, M ( Martin ), Saracino, S ( Stefano ), Maier, Felix; https://orcid.org/0000-0002-5578-723X, Scherr, Jonas, Gronau, Martin, Saracino, Stefano, Scherr, J ( Jonas ), Gronau, M ( Martin ), Saracino, S ( Stefano ), and Maier, Felix; https://orcid.org/0000-0002-5578-723X
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- 2022
17. Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders
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Wang T., Hoekzema K., Vecchio D., Wu H., Sulovari A., Coe B. P., Gillentine M. A., Wilfert A. B., Perez-Jurado L. A., Kvarnung M., Sleyp Y., Earl R. K., Rosenfeld J. A., Geisheker M. R., Han L., Du B., Barnett C., Thompson E., Shaw M., Carroll R., Friend K., Catford R., Palmer E. E., Zou X., Ou J., Li H., Guo H., Gerdts J., Avola E., Calabrese G., Elia M., Greco D., Lindstrand A., Nordgren A., Anderlid B. -M., Vandeweyer G., Van Dijck A., Van der Aa N., McKenna B., Hancarova M., Bendova S., Havlovicova M., Malerba G., Bernardina B. D., Muglia P., van Haeringen A., Hoffer M. J. V., Franke B., Cappuccio G., Delatycki M., Lockhart P. J., Manning M. A., Liu P., Scheffer I. E., Brunetti Pierri N., Rommelse N., Amaral D. G., Santen G. W. E., Trabetti E., Sedlacek Z., Michaelson J. J., Pierce K., Courchesne E., Kooy R. F., Acampado J., Ace A. J., Amatya A., Astrovskaya I., Bashar A., Brooks E., Butler M. E., Cartner L. A., Chin W., Chung W. K., Daniels A. M., Feliciano P., Fleisch C., Ganesan S., Jensen W., Lash A. E., Marini R., Myers V. J., O'Connor E., Rigby C., Robertson B. E., Shah N., Shah S., Singer E., Snyder L. A. G., Stephens A. N., Tjernagel J., Vernoia B. M., Volfovsky N., White L. C., Hsieh A., Shen Y., Zhou X., Turner T. N., Bahl E., Thomas T. R., Brueggeman L., Koomar T., Michael R. J., O'Roak B. J., Barnard R. A., Gibbs R. A., Muzny D., Sabo A., Ahmed K. L. B., Eichler E. E., Siegel M., Abbeduto L., Hilscher B. A., Li D., Smith K., Thompson S., Albright C., Butter E. M., Eldred S., Hanna N., Jones M., Coury D. L., Scherr J., Pifher T., Roby E., Dennis B., Higgins L., Brown M., Alessandri M., Gutierrez A., Hale M. N., Herbert L. M., Schneider H. L., David G., Annett R. D., Sarver D. E., Arriaga I., Camba A., Gulsrud A. C., Haley M., McCracken J. T., Sandhu S., Tafolla M., Yang W. S., Carpenter L. A., Bradley C. C., Gwynette F., Manning P., Shaffer R., Thomas C., Bernier R. A., Fox E. A., Gerdts J. A., Pepper M., Ho T., Cho D., Piven J., Lechniak H., Soorya L. V., Gordon R., Wainer A., Yeh L., Ochoa-Lubinoff C., Russo N., Berry-Kravis E., Booker S., Erickson C. A., Prock L. M., Pawlowski K. G., Matthews E. T., Brewster S. J., Hojlo M. A., Abada E., Lamarche E., Murali S. C., Harvey W. T., Kaplan H. E., Pierce K. L., DeMarco L., Horner S., Pandey J., Plate S., Sahin M., Riley K. D., Carmody E., Constantini J., Esler A., Fatemi A., Hutter H., Landa R. J., McKenzie A. P., Neely J., Singh V., Van Metre B., Wodka E. L., Fombonne E. J., Huang-Storms L. Y., Pacheco L. D., Mastel S. A., Coppola L. A., Francis S., Jarrett A., Jacob S., Lillie N., Gunderson J., Istephanous D., Simon L., Wasserberg O., Rachubinski A. L., Rosenberg C. R., Kanne S. M., Shocklee A. D., Takahashi N., Bridwell S. L., Klimczac R. L., Mahurin M. A., Cotrell H. E., Grant C. A., Hunter S. G., Martin C. L., Taylor C. M., Walsh L. K., Dent K. A., Mason A., Sziklay A., Smith C. J., Nordenskjold M., Romano C., Peeters H., Gecz J., Xia K., SPARK Consortium, Wang, T., Hoekzema, K., Vecchio, D., Wu, H., Sulovari, A., Coe, B. P., Gillentine, M. A., Wilfert, A. B., Perez-Jurado, L. A., Kvarnung, M., Sleyp, Y., Earl, R. K., Rosenfeld, J. A., Geisheker, M. R., Han, L., Du, B., Barnett, C., Thompson, E., Shaw, M., Carroll, R., Friend, K., Catford, R., Palmer, E. E., Zou, X., Ou, J., Li, H., Guo, H., Gerdts, J., Avola, E., Calabrese, G., Elia, M., Greco, D., Lindstrand, A., Nordgren, A., Anderlid, B. -M., Vandeweyer, G., Van Dijck, A., Van der Aa, N., Mckenna, B., Hancarova, M., Bendova, S., Havlovicova, M., Malerba, G., Bernardina, B. D., Muglia, P., van Haeringen, A., Hoffer, M. J. V., Franke, B., Cappuccio, G., Delatycki, M., Lockhart, P. J., Manning, M. A., Liu, P., Scheffer, I. E., Brunetti Pierri, N., Rommelse, N., Amaral, D. G., Santen, G. W. E., Trabetti, E., Sedlacek, Z., Michaelson, J. J., Pierce, K., Courchesne, E., Kooy, R. F., Acampado, J., Ace, A. J., Amatya, A., Astrovskaya, I., Bashar, A., Brooks, E., Butler, M. E., Cartner, L. A., Chin, W., Chung, W. K., Daniels, A. M., Feliciano, P., Fleisch, C., Ganesan, S., Jensen, W., Lash, A. E., Marini, R., Myers, V. J., O'Connor, E., Rigby, C., Robertson, B. E., Shah, N., Shah, S., Singer, E., Snyder, L. A. G., Stephens, A. N., Tjernagel, J., Vernoia, B. M., Volfovsky, N., White, L. C., Hsieh, A., Shen, Y., Zhou, X., Turner, T. N., Bahl, E., Thomas, T. R., Brueggeman, L., Koomar, T., Michael, R. J., O'Roak, B. J., Barnard, R. A., Gibbs, R. A., Muzny, D., Sabo, A., Ahmed, K. L. B., Eichler, E. E., Siegel, M., Abbeduto, L., Hilscher, B. A., Li, D., Smith, K., Thompson, S., Albright, C., Butter, E. M., Eldred, S., Hanna, N., Jones, M., Coury, D. L., Scherr, J., Pifher, T., Roby, E., Dennis, B., Higgins, L., Brown, M., Alessandri, M., Gutierrez, A., Hale, M. N., Herbert, L. M., Schneider, H. L., David, G., Annett, R. D., Sarver, D. E., Arriaga, I., Camba, A., Gulsrud, A. C., Haley, M., Mccracken, J. T., Sandhu, S., Tafolla, M., Yang, W. S., Carpenter, L. A., Bradley, C. C., Gwynette, F., Manning, P., Shaffer, R., Thomas, C., Bernier, R. A., Fox, E. A., Gerdts, J. A., Pepper, M., Ho, T., Cho, D., Piven, J., Lechniak, H., Soorya, L. V., Gordon, R., Wainer, A., Yeh, L., Ochoa-Lubinoff, C., Russo, N., Berry-Kravis, E., Booker, S., Erickson, C. A., Prock, L. M., Pawlowski, K. G., Matthews, E. T., Brewster, S. J., Hojlo, M. A., Abada, E., Lamarche, E., Murali, S. C., Harvey, W. T., Kaplan, H. E., Pierce, K. L., Demarco, L., Horner, S., Pandey, J., Plate, S., Sahin, M., Riley, K. D., Carmody, E., Constantini, J., Esler, A., Fatemi, A., Hutter, H., Landa, R. J., Mckenzie, A. P., Neely, J., Singh, V., Van Metre, B., Wodka, E. L., Fombonne, E. J., Huang-Storms, L. Y., Pacheco, L. D., Mastel, S. A., Coppola, L. A., Francis, S., Jarrett, A., Jacob, S., Lillie, N., Gunderson, J., Istephanous, D., Simon, L., Wasserberg, O., Rachubinski, A. L., Rosenberg, C. R., Kanne, S. M., Shocklee, A. D., Takahashi, N., Bridwell, S. L., Klimczac, R. L., Mahurin, M. A., Cotrell, H. E., Grant, C. A., Hunter, S. G., Martin, C. L., Taylor, C. M., Walsh, L. K., Dent, K. A., Mason, A., Sziklay, A., Smith, C. J., Nordenskjold, M., Romano, C., Peeters, H., Gecz, J., and Xia, K.
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0301 basic medicine ,Male ,CCCTC-Binding Factor ,Transcription Factor ,Basic Helix-Loop-Helix Transcription Factor ,DNA Mutational Analysis ,General Physics and Astronomy ,RNA-Binding Protein ,Heterogeneous-Nuclear Ribonucleoprotein U ,VARIANTS ,medicine.disease_cause ,Cohort Studies ,0302 clinical medicine ,Neurodevelopmental Disorder ,Basic Helix-Loop-Helix Transcription Factors ,SPARK Consortium ,2.1 Biological and endogenous factors ,Copy-number variation ,Aetiology ,lcsh:Science ,GABRG2 ,Genetics ,Mutation ,Multidisciplinary ,biology ,Neurodevelopmental disorders ,RNA-Binding Proteins ,High-Throughput Nucleotide Sequencing ,Autism spectrum disorders ,Multidisciplinary Sciences ,DNA-Binding Proteins ,Science & Technology - Other Topics ,Female ,Case-Control Studie ,Engineering sciences. Technology ,Human ,Science ,DNA-Binding Protein ,Genetic Association Studie ,COPY-NUMBER VARIATION ,General Biochemistry, Genetics and Molecular Biology ,DNA sequencing ,Article ,KCNQ3 Potassium Channel ,DNA Mutational Analysi ,03 medical and health sciences ,medicine ,Humans ,Genetic Predisposition to Disease ,AUTISM ,Gene ,Genetic Association Studies ,Neurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7] ,Science & Technology ,DISABILITY ,Prevention ,Case-control study ,General Chemistry ,Repressor Protein ,medicine.disease ,FRAMEWORK ,Repressor Proteins ,DE-NOVO MUTATION ,030104 developmental biology ,CTCF ,Neurodevelopmental Disorders ,Case-Control Studies ,biology.protein ,Next-generation sequencing ,Autism ,lcsh:Q ,Cohort Studie ,030217 neurology & neurosurgery ,Transcription Factors - Abstract
Most genes associated with neurodevelopmental disorders (NDDs) were identified with an excess of de novo mutations (DNMs) but the significance in case–control mutation burden analysis is unestablished. Here, we sequence 63 genes in 16,294 NDD cases and an additional 62 genes in 6,211 NDD cases. By combining these with published data, we assess a total of 125 genes in over 16,000 NDD cases and compare the mutation burden to nonpsychiatric controls from ExAC. We identify 48 genes (25 newly reported) showing significant burden of ultra-rare (MAF, For many neurodevelopmental disorder (NDD) risk genes, the significance for mutational burden is unestablished. Here, the authors sequence 125 candidate NDD genes in over 16,000 NDD cases; case-control mutational burden analysis identifies 48 genes with a significant burden of severe ultra-rare mutations.
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- 2020
18. Sports medicine and sports psychiatry
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Scherr, J, primary and Claussen, MC, additional
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- 2021
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19. Sports psychiatric examination in competitive sports
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Gonzalez Hofmann, C, primary, Wyssen, A, additional, Schorb, A, additional, Allroggen, M, additional, Dallmann, P, additional, Schmidt, RE, additional, Graffius, S-T, additional, Niebauer, J, additional, Herfert, J, additional, Fröhlich, S, additional, Scherr, J, additional, and Claussen, MC, additional
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- 2021
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20. Sports psychiatry and medical views on mild traumatic brain injury in competitive sport: a current review and recommendations
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Gonzalez Hofmann, C, primary, Fontana, R, additional, Parker, T, additional, Deutschmann, M, additional, Dewey, M, additional, Reinsberger, C, additional, Claussen, MC, additional, Scherr, J, additional, and Jeckell, AS, additional
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- 2021
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21. Overtraining from a sports psychiatry perspective
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Schorb, A, primary, Niebauer, J, additional, Aichhorn, W, additional, Schiepek, G, additional, Scherr, J, additional, and Claussen, MC, additional
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- 2021
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22. Cardiovascular disease and excess mortality in depression: physical activity as a game changer
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Gerber, M, primary, Claussen, MC, additional, Cody, R, additional, Imboden, C, additional, Ludyga, S, additional, Scherr, J, additional, Seifritz, E, additional, and von Känel, R, additional
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- 2021
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23. Position paper: sports psychiatric care provision in competitive sports
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Claussen, MC, primary, Gonzalez Hofmann, C, additional, Schneeberger, AR, additional, Seifritz, E, additional, Schorb, A, additional, Allroggen, M, additional, Freyer, T, additional, Helmig, F, additional, Niebauer, J, additional, Hefert, J, additional, Klostermeier, E, additional, Fröhlich, S, additional, and Scherr, J, additional
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- 2021
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24. Merkblatt: Sportpsychiatrische und -psychotherapeutische Aspekte im Leistungssport in Zeiten der COVID-19-Pandemie
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Claussen, M C, Fröhlich, S, Spörri, J, Hasan, A, Seifritz, E, Scherr, J, Markser, V Z, University of Zurich, and Claussen, M C
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2732 Orthopedics and Sports Medicine ,610 Medicine & health ,10046 Balgrist University Hospital, Swiss Spinal Cord Injury Center ,3612 Physical Therapy, Sports Therapy and Rehabilitation - Published
- 2020
25. Author Correction: Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders (Nature Communications, (2020), 11, 1, (4932), 10.1038/s41467-020-18723-y)
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Wang, T., Hoekzema, K., Vecchio, Davide., Wu, H., Sulovari, A., Coe, B. P., Gillentine, M. A., Wilfert, A. B., Perez-Jurado, L. A., Kvarnung, M., Sleyp, Y., Earl, R. K., Rosenfeld, J. A., Geisheker, M. R., Han, L., Du, B., Barnett, C., Thompson, E., Shaw, M., Carroll, R., Friend, K., Catford, R., Palmer, E. E., Zou, X., Ou, J., Li, H., Guo, H., Gerdts, J., Avola, E., Calabrese, Giuseppe, Elia, Maurizio., Greco, Donatella, Lindstrand, A., Nordgren, A., Anderlid, B. -M., Vandeweyer, G., Van Dijck, A., Van der Aa, N., Mckenna, B., Hancarova, M., Bendova, S., Havlovicova, M., Malerba, G., Bernardina, B. D., Muglia, P., van Haeringen, A., Hoffer, M. J. V., Franke, B., Cappuccio, G., Delatycki, M., Lockhart, P. J., Manning, M. A., Liu, P., Scheffer, I. E., Brunetti-Pierri, N., Rommelse, N., Amaral, D. G., Santen, G. W. E., Trabetti, E., Sedlacek, Z., Michaelson, J. J., Pierce, K., Courchesne, E., Kooy, R. F., Acampado, J., Ace, A. J., Amatya, A., Astrovskaya, I., Bashar, A., Brooks, E., Butler, M. E., Cartner, L. A., Chin, W., Chung, W. K., Daniels, A. M., Feliciano, P., Fleisch, C., Ganesan, S., Jensen, W., Lash, A. E., Marini, R., Myers, V. J., O'Connor, E., Rigby, C., Robertson, B. E., Shah, N., Shah, S., Singer, E., Snyder, L. A. G., Stephens, A. N., Tjernagel, J., Vernoia, B. M., Volfovsky, N., White, L. C., Hsieh, A., Shen, Y., Zhou, X., Turner, T. N., Bahl, E., Thomas, T. R., Brueggeman, L., Koomar, T., O'Roak, B. J., Barnard, R. A., Gibbs, R. A., Muzny, D., Sabo, A., Ahmed, K. L. B., Eichler, E. E., Siegel, M., Abbeduto, L., Hilscher, B. A., Li, D., Smith, K., Thompson, S., Albright, C., Butter, E. M., Eldred, S., Hanna, N., Jones, M., Coury, D. L., Scherr, J., Pifher, T., Roby, E., Dennis, B., Higgins, L., Brown, M., Alessandri, M., Gutierrez, A., Hale, M. N., Herbert, L. M., Schneider, H. L., David, G., Annett, R. D., Sarver, D. E., Arriaga, I., Camba, A., Gulsrud, A. C., Haley, M., Mccracken, J. T., Sandhu, S., Tafolla, M., Yang, W. S., Carpenter, L. A., Bradley, C. C., Gwynette, F., Manning, P., Shaffer, R., Thomas, C., Bernier, R. A., Fox, E. A., Gerdts, J. A., Pepper, M., Ho, T., Cho, D., Piven, J., Lechniak, H., Soorya, L. V., Gordon, R., Wainer, A., Yeh, L., Ochoa-Lubinoff, C., Russo, N., Berry-Kravis, E., Booker, S., Erickson, C. A., Prock, L. M., Pawlowski, K. G., Matthews, E. T., Brewster, S. J., Hojlo, M. A., Abada, E., Lamarche, E., Murali, S. C., Harvey, W. T., Kaplan, H. E., Pierce, K. L., Demarco, L., Horner, S., Pandey, J., Plate, S., Sahin, M., Riley, K. D., Carmody, E., Constantini, J., Esler, A., Fatemi, A., Hutter, H., Landa, R. J., Mckenzie, A. P., Neely, J., Singh, V., Van Metre, B., Wodka, E. L., Fombonne, E. J., Huang-Storms, L. Y., Pacheco, L. D., Mastel, S. A., Coppola, L. A., Francis, S., Jarrett, A., Jacob, S., Lillie, N., Gunderson, J., Istephanous, D., Simon, L., Wasserberg, O., Rachubinski, A. L., Rosenberg, C. R., Kanne, S. M., Shocklee, A. D., Takahashi, N., Bridwell, S. L., Klimczac, R. L., Mahurin, M. A., Cotrell, H. E., Grant, C. A., Hunter, S. G., Martin, C. L., Taylor, C. M., Walsh, L. K., Dent, K. A., Mason, A., Sziklay, A., Smith, C. J., Nordenskjold, M., Romano, Corrado, Peeters, H., Gecz, J., and Xia, K.
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- 2020
26. Prospective long-term follow-up analysis of the cardiovascular system in marathon runners: study design of the Pro-MagIC study
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Schoenfeld, J, Schindler, MJ, Haller, B, Holdenrieder, S, Nieman, DC, Halle, M, La Gerche, A, Scherr, J, Schoenfeld, J, Schindler, MJ, Haller, B, Holdenrieder, S, Nieman, DC, Halle, M, La Gerche, A, and Scherr, J
- Abstract
INTRODUCTION: Prolonged strenuous exercise training may result in structural, functional and electrical cardiac remodelling, as well as vascular and myocardial injuries. However, the extent to which high-volume, intense exercise is associated with arrhythmias, myocardial fibrosis, coronary heart disease and pathological alterations of the vasculature remains unknown. In addition, there is no clear consensus on the clinical significance of these exercise-induced changes. Previous studies typically used cross-sectional designs and examined exercise-induced cardiovascular changes in small cohorts of athletes for up to 3-7 days of recovery. Long-term longitudinal studies investigating cardiovascular changes induced by prolonged strenuous exercise in large cohorts of athletes are needed to improve scientific understanding in this area. METHODS AND ANALYSIS: In this prospective observational monocenter study, 277 participants of the Beer, Marathon, Genetics, Inflammation and the Cardiovascular System (Be-MaGIC) study (ClinicalTrials.gov: NCT00933218) will be invited to participate in this 10-year follow-up study. A minimum target sample size of 130 participants will be included in the study. Participating athletes will be examined via the following: anthropometry, resting electrocardiography and echocardiography, blood sampling, retinal vessel diameters, carotid sonography and cardiopulmonary exercise testing, including exercise electrocardiography. DISCUSSION: This longitudinal study will provide comprehensive data on physiological changes in the cardiovascular system and the development of pathologies after a 10-year period of prolonged and strenuous endurance exercise. Since the participants will have engaged in a wide range of training loads and competitive race events, this study will provide useful risk factor determinants and training load cut-off values. The primary endpoint is the association between the exercise-induced increase in cardiac troponin during the Mu
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- 2020
27. Kardiozirkulatorische Notfälle
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Brokmann, Jörg Christian, Rossaint, Rolf, Brokmann, J C ( Jörg Christian ), Rossaint, R ( Rolf ), Scherr, J C, Scherr, B F, Brokmann, Jörg Christian, Rossaint, Rolf, Brokmann, J C ( Jörg Christian ), Rossaint, R ( Rolf ), Scherr, J C, and Scherr, B F
- Abstract
In diesem Kapitel werden kardiozirkulatorische Notfälle erläutert, welche einen Schwerpunkt der notärztlichen Tätigkeit darstellen. Vom akuten Koronarsyndrom, über Herzinsuffizienz bis zur Beschreibung der Schockformen werden die Essentials erörtert.
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- 2020
28. Mental health in competitive sports in times of COVID-19
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Claussen, M C; https://orcid.org/0000-0002-8415-3076, Zimmermann, S M, Spörri, J, Seifritz, E, Scherr, J, Fröhlich, S, Claussen, M C; https://orcid.org/0000-0002-8415-3076, Zimmermann, S M, Spörri, J, Seifritz, E, Scherr, J, and Fröhlich, S
- Published
- 2020
29. Merkblatt: Sportpsychiatrische und -psychotherapeutische Aspekte im Leistungssport in Zeiten der COVID-19-Pandemie
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Claussen, M C; https://orcid.org/0000-0002-8415-3076, Fröhlich, S, Spörri, J, Hasan, A, Seifritz, E, Scherr, J, Markser, V Z, Claussen, M C; https://orcid.org/0000-0002-8415-3076, Fröhlich, S, Spörri, J, Hasan, A, Seifritz, E, Scherr, J, and Markser, V Z
- Abstract
Psychische und soziale Belastungen sind wie körperliche Belastungen fester Bestandteil des Leistungssports. Bis vor wenigen Jahren wurde angenommen, dass es im Leistungssport keine ernsthaften psychischen Probleme und Erkrankungen geben kann und das mentale Stärke gleichzeitig auch psychische Gesundheit bedeutet (3). Durch immer zahlreich werdende Veröffentlichungen wissen wir mittlerweile, dass psychische Belastungen und Erkrankungen häufige Gesundheitsprobleme im Leistungssport sind, die sich sportspezifisch manifestieren und die Leistung vermindern können (5). Erfolgreiche Spitzensportler lehrten uns zudem mit ihren mutigen Interviews, dass ihre mentale Stärke und Wettkampfpersönlichkeit kein Garant für eine anhaltende psychische Gesundheit sein muss.
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- 2020
30. Inter-individual differences in the response to an exercise training intervention in patients with metabolic syndrome
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Von Korn, P, primary, Kia, S, additional, Lechner, K, additional, Dinges, S, additional, Duvinage, A, additional, Scherr, J, additional, Landmesser, U, additional, Halle, M, additional, and Kraenkel, N, additional
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- 2020
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31. Fact sheet: Sport psychiatric andpsychotherapeutic aspects in competitive sports in times of the COVID 19 pandemic
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Claussen, MC, primary, Fröhlich, S, additional, Spörri, J, additional, Hasan, A, additional, Seifritz, E, additional, Scherr, J, additional, and Markser, VZ, additional
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- 2020
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32. Position stand: return to sport in the current Coronavirus pandemic (SARS-CoV-2 / COVID-19)
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Nieß, AM, primary, Bloch, W, additional, Friedmann-Bette, B, additional, Grim, C, additional, Halle, M, additional, Hirschmüller, A, additional, Kopp, C, additional, Meyer, T, additional, Niebauer, J, additional, Reinsberger, C, additional, Röcker, K, additional, Scharhag, J, additional, Scherr, J, additional, Schneider, C, additional, Steinacker, JM, additional, Urhausen, A, additional, Wolfarth, B, additional, and Mayer, F, additional
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- 2020
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33. Recommendations for exercise testing in sports medicine during the current pandemic situation (SARS-CoV-2 / COVID-19)
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Nieß, AM, primary, Bloch, W, additional, Friedmann-Bette, B, additional, Grim, C, additional, Gärtner, B*, additional, Halle, M, additional, Hirschmüller, A, additional, Kopp, C, additional, Meyer, T, additional, Niebauer, J, additional, Predel, G, additional, Reinsberger, C, additional, Röcker, K, additional, Scharhag, J, additional, Schneider, C, additional, Scherr, J, additional, Steinacker, JM, additional, Mayer, F, additional, and Wolfarth, B, additional
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- 2020
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34. Psyche and sport in times of COVID-19
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Claussen, MC, primary, Fröhlich, S, additional, Spörri, J, additional, Seifritz, E, additional, Markser, VZ, additional, and Scherr, J, additional
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- 2020
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35. Fact Sheet: Health Situation for Athletes in the Current Coronavirus Pandemic (SARS-CoV-2 / COVID-19)
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Steinacker, JM, primary, Bloch, W, additional, Halle, H, additional, Mayer, F, additional, Meyer, T, additional, Hirschmüller, A, additional, Röcker, K, additional, Nieß, A, additional, Scharhag, J, additional, Reinsberger, C, additional, Scherr, J, additional, Niebauer, J, additional, Wolfarth, B, additional, Hannafin, J, additional, Hiura, M, additional, Wilkinson, M, additional, Koubaa, D, additional, Poli, P, additional, Smoljanovic, T, additional, Nielsen, HB, additional, Ackerman, K, additional, and Wilson, F, additional
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- 2020
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36. Vitamin D and athletic performance: perspectives and pitfalls
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Lechner, K, primary, Lechner, B, additional, Engel, H, additional, Halle, M, additional, Worm, N*, additional, and Scherr, J*, additional
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- 2020
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37. SPARK: A US Cohort of 50,000 Families to Accelerate Autism Research
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Feliciano, P, Daniels, AM, Green Snyder, LA, Beaumont, A, Camba, A, Esler, A, Gulsrud, AG, Mason, A, Gutierrez, A, Nicholson, A, Paolicelli, AM, McKenzie, AP, Rachubinski, AL, Stephens, AN, Simon, AR, Stedman, A, Shocklee, AD, Swanson, A, Finucane, B, Hilscher, BA, Hauf, B, O'Roak, BJ, McKenna, B, Robertson, BE, Rodriguez, B, Vernoia, BM, Van Metre, B, Bradley, C, Cohen, C, Erickson, CA, Harkins, C, Hayes, C, Lord, C, Martin, CL, Ortiz, C, Ochoa-Lubinoff, C, Peura, C, Rice, CE, Rosenberg, CR, Smith, CJ, Thomas, C, Taylor, CM, White, LC, Walston, CH, Amaral, DG, Coury, DL, Sarver, DE, Istephanous, D, Li, D, Nugyen, DC, Fox, EA, Butter, EM, Berry-Kravis, E, Courchesne, E, Fombonne, EJ, Hofammann, E, Lamarche, E, Wodka, EL, Matthews, ET, O'Connor, E, Palen, E, Miller, F, Dichter, GS, Marzano, G, Stein, G, Hutter, H, Kaplan, HE, Li, H, Lechniak, H, Schneider, HL, Zaydens, H, Arriaga, I, Gerdts, JA, Cubells, JF, Cordova, JM, Gunderson, J, Lillard, J, Manoharan, J, McCracken, JT, Michaelson, JJ, Neely, J, Orobio, J, Pandey, J, Piven, J, Scherr, J, Sutcliffe, JS, Tjernagel, J, Wallace, J, Callahan, K, Dent, K, Schweers, KA, Hamer, KE, Law, JK, Lowe, K, O'Brien, K, Smith, K, Pawlowski, KG, Pierce, KL, Roeder, K, and Abbeduto, LJ
- Abstract
© 2018 Elsevier Inc. The Simons Foundation Autism Research Initiative (SFARI) has launched SPARKForAutism.org, a dynamic platform that is engaging thousands of individuals with autism spectrum disorder (ASD) and connecting them to researchers. By making all data accessible, SPARK seeks to increase our understanding of ASD and accelerate new supports and treatments for ASD. The Simons Foundation Autism Research Initiative (SFARI) has launched SPARKForAutism.org, a dynamic platform that is engaging thousands of individuals with autism spectrum disorder (ASD) and connecting them to researchers. By making all data accessible, SPARK seeks to increase our understanding of ASD and accelerate new supports and treatments for ASD.
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- 2018
38. Physiological extremes of the human serum metabolome. The MetaExtreme study
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Sportbiologie, Schranner D, Schönfelder M, Römisch-Margl W, Kaps S, Söhnlein Q, Scherr J, Zelger O, Halle M, Schlegel J, Stöcker F, Kreuzpointner F, Riermeier A, Geyer P, Murgia M, Kastenmüller G, Wackerhage H, Sportbiologie, and Schranner D, Schönfelder M, Römisch-Margl W, Kaps S, Söhnlein Q, Scherr J, Zelger O, Halle M, Schlegel J, Stöcker F, Kreuzpointner F, Riermeier A, Geyer P, Murgia M, Kastenmüller G, Wackerhage H
- Published
- 2018
39. P628Development and validation of a standardized method to quantify the oxygen pulse curve during cardiopulmonary exercise testing
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Mueller, S, primary, Schneider, A, additional, Duvinage, A, additional, Suchy, C, additional, Haller, B, additional, Scherr, J, additional, Scharhag, J, additional, and Halle, M, additional
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- 2018
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40. Changes of intima-media thickness in marathon runners: A mid-term follow-up
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Müller J, Dahm V, Lorenz ES, Pressler A, Haller B, Grabs V, Halle M, Scherr J and Müller J, Dahm V, Lorenz ES, Pressler A, Haller B, Grabs V, Halle M, Scherr J
- Published
- 2016
41. T-wave inversions in elite athletes: the best predictors have yet to be determined
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Pressler, A., primary, Scherr, J., additional, Wolfarth, B., additional, and Halle, M., additional
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- 2009
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42. Poisons for Export
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Ahmed, K. and Scherr, J.
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Commerce -- International aspects ,Hazardous substances -- International trade ,Business, general ,Law - Published
- 1981
43. [s.n.]
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Scherr, J. and Scherr, J.
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- 1943
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44. Jump performance and movement quality in 7- to 15-year-old competitive alpine skiers: a cross-sectional study.
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Hanimann J, Raschle N, Schmid NE, Bruhin B, Frey WO, Scherr J, de Bruin ED, and Spörri J
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- Humans, Cross-Sectional Studies, Adolescent, Female, Male, Child, Movement physiology, Reproducibility of Results, Sex Factors, Age Factors, Skiing physiology, Athletic Performance physiology, Athletic Performance statistics & numerical data
- Abstract
Introduction: Injury rates in competitive alpine skiing are high. With current methods, identifying people at risk is expensive and thus often not feasible at the youth level. The aims of this study were (1) to describe the jump performance and movement quality of youth competitive alpine skiers according to age and sex, (2) to compare the jump distance among skiers of different sexes and movement quality grades, and (3) to assess the inter-rater grading reliability of the qualitative visual movement quality classification of such jumps and the agreement between live and video-based post-exercise grading., Materials and Methods: This cross-sectional study is based on an anonymized dataset of 301 7- to 15-year-old competitive alpine skiers. The skiers performed two-legged forward triple jumps, whereby the jump distance was measured, and grades were assigned by experienced raters from the frontal and sagittal perspectives depending on the execution quality of the jumps. Furthermore, jumps were filmed and ultimately rated post-exercise. Differences in jump distance between various groups were assessed by multivariate analyses of variance (MANOVAs). Reliability was determined using Kendall's coefficient of concordance., Results: The jump distance was significantly greater in U16 skiers than in U11 skiers of both sexes and in skiers with good execution quality than in those with reduced or poor execution quality. Overall, jump distance in U16 skiers significantly differed between female (5.37 m with 95% CI [5.21, 5.53]) and male skiers (5.90 m with 95%CI [5.69, 6.10]). Slightly better inter-rater grading reliability was observed for video-based post-exercise ( strong agreement) ratings than for live ratings ( moderate agreement)., Conclusion: In competitive alpine skiers aged 7 to 15 years, jump performance increases with age, and around puberty, sex differences start to manifest. Our results highlight the importance of evaluating both jump distance and movement quality in youth skiers. To improve test-retest reliability, however, a video-based post-exercise evaluation is recommended.
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- 2024
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45. Superolateral Hoffa fat pad edema in adolescent competitive alpine skiers: temporal evolution over 4 years and risk factors.
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Feuerriegel GC, Marth AA, Fröhlich S, Scherr J, Spörri J, and Sutter R
- Abstract
Objectives: To longitudinally assess and correlate the prevalence of superolateral Hoffa fat pad (SHFP) edema with changes in features of the knee extensor mechanism in adolescent competitive alpine skiers over 48 months., Methods: Competitive alpine skiers were prospectively enrolled in 2018 and underwent bilateral knee MRI at baseline and after 48 months. MRI was assessed for the prevalence of SHFP edema. Features of the knee extensor mechanism were assessed by measuring the trochlear sulcus angle and depth, lateral and medial trochlear inclination, trochlear angle, patella tilt, Insall‒Salvati ratio (ISR), and patellar ligament to lateral trochlear facet (PL-T) distance. Separate logistic regression models were used to calculate the odds ratios between each measurement and the presence of SHFP edema at both time points., Results: Sixty-three athletes were included in the study (mean age 15.3 ± 1.3 years, 25 women). At baseline, 23 knees had SHFP edema, increasing to 34 knees at the 48-month follow-up. At baseline, knees with measurements in the highest quartile for ISR and lowest quartile for trochlear depth and PL-T were 9.3, 5.1, and 7.7 times more likely to show SHFP edema, respectively. At follow-up, these correlations were confirmed and additionally, knees with measurements in the highest quartile for trochlear sulcus angle and the lowest quartile for lateral trochlear inclination were 4.1 and 3.4 times more likely to show SHFP edema., Conclusion: An increased prevalence of SHFP edema in competitive alpine skiers during adolescence was associated with persistent high-riding patella, reduced patellar ligament to trochlear distance, and flattened lateral trochlear facet., Critical Relevance Statement: In clinical routine, assessment of the mechanical properties of the knee extensor mechanism, together with anatomical developments during adolescence, may improve the understanding and management of patellofemoral instability., Key Points: • Superolateral Hoffa fat pad (SHFP) edema is a frequent cause of anterolateral knee pain but the role of predisposing factors is still debated. • A higher prevalence of SHFP edema was associated with high-riding patella, reduced patellar ligament to trochlear distance, and flattened lateral trochlear facet. • Understanding of the mechanical interaction and the anatomical development of the knee during adolescence provides further insight into the development of SHFP edema., (© 2024. The Author(s).)
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- 2024
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46. Exercise- and education-based prehabilitation before total knee arthroplasty: a pilot study.
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Gränicher P, Mulder L, Lenssen T, Fucentese SF, Swanenburg J, De Bie R, and Scherr J
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- Humans, Aged, Pilot Projects, Exercise, Knee Joint, Preoperative Exercise, Arthroplasty, Replacement, Knee
- Abstract
Objective: To determine the feasibility and estimates of effects of a supervised exercise- and education-based prehabilitation programme aiming to improve knee functioning compared with usual care in patients awaiting total knee arthroplasty., Design: A randomized controlled pilot study., Subjects: Patients receiving primary, unilateral total knee arthroplasty., Methods: Patients randomized to the intervention group participated in a personalized 4-8-week prehabilitation programme before surgery. Feasibility of the intervention and self-reported knee functioning, pain, physical performance and hospital stay were assessed at baseline, immediately preoperatively, 6 and 12 weeks after surgery., Results: Twenty patients (mean age 72.7±5.95 years) were enrolled in this study. The personalized prehabilitation programme was found to be feasible and safe, with an exercise adherence of 90%. Significant medium interaction effects between groups and over time favouring prehabilitation were reported for the sport subscale of the Knee Osteoarthritis Outcome Score (F(3/54) = 2.895, p = 0.043, η² = 0.139) and Tegner Activity Scale (F(2.2/39.1) = 3.20, p = 0.048, η² = 0.151)., Conclusion: The absence of adverse events and high adherence to the programme, coupled with beneficial changes shown in the intervention group, support the conduct of a full-scale trial investigating the effectiveness of prehabilitation.
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- 2024
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47. Health problems occurring in national-level female soccer players are different between leagues and throughout the season: a 6-month prospective cohort study.
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Dettwiler A, Wieloch N, Fröhlich S, Imhoff F, Scherr J, and Spörri J
- Abstract
Objectives: This study investigated the prevalence and severity of health problems in national-level female soccer players with respect to league and seasonality., Methods: In a prospective cohort study, 46 female soccer players aged 22.8±3.9 years playing in the three highest leagues in Switzerland were surveyed biweekly using the Oslo Sports Trauma Research Centre health problem (OSTRC-H) questionnaire. All definitions and measures followed the OSTRC-H-specific recommendations. The 6-month observation period included parts of the off-season and one half of the match season., Results: The average 2-weekly health problem prevalence was 37.3% (illnesses: 8.8%; sudden onset injuries-both acute and repetitive mechanisms: 19.7%; repetitive gradual onset injuries: 12.4%) and 25.1% for substantial problems as defined in the OSTRC-H context (7.3%; 12.0% and 7.3%, respectively). The absolute injury rates amounted to 148 injuries per 100 players per half season, of which 96 injuries per 100 players per half season were substantial. Female players in the 2nd and 3rd highest national leagues showed more gradual onset injuries (p<0.001) and fewer illnesses than those in the top league (p<0.05). At the same time, there were no league-specific differences in sudden onset injuries. Such injuries had a higher cumulative severity score than gradual onset injuries. Among sudden onset injuries, the ankle was the most affected body part, while the thigh was affected by for gradual onset injuries. The average 2-weekly health problem prevalence values steadily increased during the match season., Conclusion: Among national-level female soccer players, the risk of health problems is relatively high and differs between leagues and across seasons., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
- Published
- 2023
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48. Call for the application of a biopsychosocial and interdisciplinary approach to the return-to-sport framework of snow sports athletes.
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Müller PO, Taylor J, Jordan MJ, Scherr J, Verhagen E, Collins D, and Spörri J
- Abstract
Snow sports such as alpine skiing or snowboarding are associated with a high risk of injury and reinjury and are subject to a very special environment with specific rehabilitation challenges that must be addressed. Due to geographic decentralisation, seasonal climatic limitations, alternation of training in off-snow and on-snow settings and unique loading patterns of practising these sports, special rehabilitation structures and processes are required compared with other sports. In addition, returning to preinjury performance requires a high level of confidence and a resumption of risk-taking in demanding situations such as high-speed skiing and high-amplitude jumps. A biopsychosocial and interdisciplinary approach can be viewed as a holistic, athlete-centred approach that promotes interprofessional communication and collaboration. This is particularly central for managing the physical/biological, psychological and social demands of injury management for snow sports. It can help ensure that rehabilitation content is well coordinated and tailored to individual needs. This is because transitions between different rehabilitation phases and caring professionals are well aligned, and rehabilitation is understood not only as purely 'physical recovery' but also as 'psychological recovery' considering the snow sports-specific setting with specific social norms. Ultimately, this may improve the rehabilitation success of snow sports athletes., Competing Interests: Competing interests: EV is the editor-in-chief of BMJ Open Sports and Exercise Medicine., (© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
- Published
- 2023
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49. De Novo Lipogenesis-Related Monounsaturated Fatty Acids in the Blood Are Associated with Cardiovascular Risk Factors in HFpEF Patients.
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Bock M, von Schacky C, Scherr J, Lorenz E, Lechner B, Krannich A, Wachter R, Duvinage A, Edelmann F, and Lechner K
- Abstract
De novo lipogenesis (DNL)-related monounsaturated fatty acids (MUFAs) in the blood are associated with incident heart failure (HF). This observation's biological plausibility may be due to the potential of these MUFAs to induce proinflammatory pathways, endoplasmic reticulum stress, and insulin resistance, which are pathophysiologically relevant in HF. The associations of circulating MUFAs with cardiometabolic phenotypes in patients with heart failure with a preserved ejection fraction (HFpEF) are unknown. In this secondary analysis of the Aldosterone in Diastolic Heart Failure trial, circulating MUFAs were analysed in 404 patients using the HS-Omega-3-Index
® methodology. Patients were 67 ± 8 years old, 53% female, NYHA II/III (87/13%). The ejection fraction was ≥50%, E/e' 7.1 ± 1.5, and the median NT-proBNP 158 ng/L (IQR 82-298). Associations of MUFAs with metabolic, functional, and echocardiographic patient characteristics at baseline/12 months follow-up (12 mFU) were analysed using Spearman's correlation coefficients and linear regression analyses, using sex/age as covariates. Circulating levels of C16:1n7 and C18:1n9 were positively associated with BMI/truncal adiposity and associated traits (dysglycemia, atherogenic dyslipidemia, and biomarkers suggestive of non-alcoholic-fatty liver disease). They were furthermore inversely associated with functional capacity at baseline/12 mFU. In contrast, higher levels of C20:1n9 and C24:1n9 were associated with lower cardiometabolic risk and higher exercise capacity at baseline/12 mFU. In patients with HFpEF, circulating levels of individual MUFAs were differentially associated with cardiovascular risk factors. Our findings speak against categorizing FA based on physicochemical properties. Circulating MUFAs may warrant further investigation as prognostic markers in HFpEF.- Published
- 2023
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50. Association of Gene Variants with Seasonal Variation in Muscle Strength and Aerobic Capacity in Elite Skiers.
- Author
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Gasser B, Frey WO, Valdivieso P, Scherr J, Spörri J, and Flück M
- Subjects
- Male, Humans, Female, Seasons, Muscle, Skeletal physiology, Lactic Acid, Actinin, Oxygen Consumption genetics, Muscle Strength genetics
- Abstract
Background: The training of elite skiers follows a systematic seasonal periodization with a preparation period, when anaerobic muscle strength, aerobic capacity, and cardio-metabolic recovery are specifically conditioned to provide extra capacity for developing ski-specific physical fitness in the subsequent competition period. We hypothesized that periodization-induced alterations in muscle and metabolic performance demonstrate important variability, which in part is explained by gene-associated factors in association with sex and age. Methods: A total of 34 elite skiers (20.4 ± 3.1 years, 19 women, 15 men) underwent exhaustive cardiopulmonary exercise and isokinetic strength testing before and after the preparation and subsequent competition periods of the World Cup skiing seasons 2015-2018. Biometric data were recorded, and frequent polymorphisms in five fitness genes, ACE-I/D (rs1799752), TNC (rs2104772), ACTN3 (rs1815739), and PTK2 (rs7460, rs7843014), were determined with specific PCR reactions on collected DNA. Relative percentage changes of cardio-pulmonary and skeletal muscle metabolism and performance over the two seasonal periods were calculated for 160 data points and subjected to analysis of variance (ANOVA) to identify hypothesized and novel associations between performance alterations and the five respective genotypes and determine the influence of age × sex. A threshold of 0.1 for the effect size (h2) was deemed appropriate to identify relevant associations and motivate a post hoc test to localize effects. Results: The preparation and competition periods produced antidromic functional changes, the extent of which varied with increasing importance for anaerobic strength, aerobic performance, cardio-metabolic efficiency, and cardio-metabolic/muscle recovery. Only peak RER (-14%), but not anaerobic strength and peak aerobic performance, and parameters characterizing cardio-metabolic efficiency, differed between the first and last studied skiing seasons because improvements over the preparation period were mostly lost over the competition period. A number of functional parameters demonstrated associations of variability in periodic changes with a given genotype, and this was considerably influenced by athlete "age", but not "sex". This concerned age-dependent associations between periodic changes in muscle-related parameters, such as anaerobic strength for low and high angular velocities of extension and flexion and blood lactate concentration, with rs1799752 and rs2104772, whose gene products relate to sarcopenia. By contrast, the variance in period-dependent changes in body mass and peak VO2 with rs1799752 and rs2104772, respectively, was independent of age. Likely, the variance in periodic changes in the reliance of aerobic performance on lactate, oxygen uptake, and heart rate was associated with rs1815739 independent of age. These associations manifested at the post hoc level in genotype-associated differences in critical performance parameters. ACTN3 T-allele carriers demonstrated, compared to non-carriers, largely different periodic changes in the muscle-associated parameters of aerobic metabolism during exhaustive exercise, including blood lactate and respiration exchange ratio. The homozygous T-allele carriers of rs2104772 demonstrated the largest changes in extension strength at low angular velocity during the preparation period. Conclusions: Physiological characteristics of performance in skiing athletes undergo training period-dependent seasonal alterations the extent of which is largest for muscle metabolism-related parameters. Genotype associations for the variability in changes of aerobic metabolism-associated power output during exhaustive exercise and anaerobic peak power over the preparation and competition period motivate personalized training regimes. This may help to predict and maximize the benefit of physical conditioning of elite skiers based on chronological characteristics and the polymorphisms of the ACTN3, ACE, and TNC genes investigated here.
- Published
- 2023
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