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13 results on '"Shehata, Mahmoud M."'

1. MERS coronaviruses in dromedary camels, Egypt

Author

Chu, Daniel K.W., Poon, Leo L.M., Gomaa, Mokhtar M., Shehata, Mahmoud M., Perera, Ranawaka A.P.M., Zeid, Dina Abu, Rifay, Amira S. El, Siu, Lewis Y., Guan, Yi, Webby, Richard J., Ali, Mohamed A., Peiris, Malik, and Kayali, Ghazi

Subjects
Genomics -- Health aspects, Genomes -- Health aspects, Health
Abstract

Middle East respiratory syndrome (MERS) is a pneumonic illness caused by a novel lineage C beta-coronavirus (CoV). During September 2012-January 20, 2014, a total of 178 confirmed cases in humans [...]

Published
2014

2. Active surveillance for avian influenza virus, Egypt, 2010-2012

Author

Kayali, Ghazi, Kandeil, Ahmed, Shesheny, Rabeh El-, Kayed, Ahmed S., Gomaa, Mokhtar M., Maatouq, Asmaa M., Shehata, Mahmoud M., Moatasim, Yassmin, Bagato, Ola, Cai, Zhipeng, Rubrum, Adam, Kutkat, Mohamed A., McKenzie, Pamela P., Webster, Robert G., Webby, Richard J., and Ali, Mohamed A.

Subjects
Avian influenza -- Analysis, Avian influenza viruses -- Analysis, Earthquakes -- Egypt -- Analysis, Poultry industry -- Analysis, Genetic transcription -- Analysis, Health, World Health Organization
Abstract

In 2008, highly pathogenic avian influenza (HPAI) A(H5N1) virus became enzootic among poultry in Egypt, and the country became an epicenter for virus activity (1). As the established viruses drifted [...]

Published
2014
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3. Socializing One Health: an innovative strategy to investigate social and behavioral risks of emerging viral threats

Author

Saylors, Karen, Wolking, David J., Hagan, Emily, Martinez, Stephanie, Francisco, Leilani, Euren, Jason, Olson, Sarah H., Miller, Maureen, Fine, Amanda E., Thanh, Nga Nguyen Thi, Tran Minh, Phuc, Kalengkongan, Jusuf D., Kusumaningrum, Tina, Latinne, Alice, Pamungkas, Joko, Safari, Dodi, Saputro, Suryo, Bamba, Djeneba, Coulibaly, Kalpy Julien, Dosso, Mireille, Laudisoit, Anne, N'guettia Jean, Kouassi Manzan, Dutta, Shusmita, Islam, Ariful, Shano, Shahanaj, Mwanzalila, Mwokozi I., Trupin, Ian P., Gbakima, Aiah, Bangura, James, Yondah, Sylvester T., Karmacharya, Dibesh, Shrestha, Rima D., Kamta, Marcelle Annie Matsida, Mouiche, Mohamed Moctar Mouliom, Ndolo, Hilarion Moukala, Niama, Fabien Roch, Onikrotin, Dionne, Daszak, Peter, Johnson, Christine K., Mazet, Jonna A. K., Abaneh, Ola, Ababneh, Mustafa, Rafia, Jum, Sukor, Abd, Abdullah, Mohd Lufti, Abedin, Josefina, Abu-Basha, Ehab, Ali, Mohamed, Beal Akoundze, Junior, Akpaki, Joel, Al Hanandeh, Sief Addeen, Al Omari, Bilal, Al Shakil, Abdullah, Al-Zghoul, Mohammed, Albart, Stephenie Ann, Alshammari, Abdullah, Amarneh, Basil H., Ampofo, William, Andrew, Victoria, Ahn, Dao Le, Ankhanbaatar, Ulaankhuu, Anthony, Simon, Antonjaya, Ungke, Araya, Kidan, Arku, Jallah, Arshat, Norsharina, Asigbee, Theodore, Aung, Ohnmar, Awuni, Joseph, Ayukebong, James, Azian, Mohammed, Aziz, Nor Adilah, Ba, Aminata, Bassan, Ganzorig, Bagato, Ola, Bamba, Aboubacar, Bamba, Djenba, Barkhasbaatar, Ariunbaatar, Barrera, June, Basaraba, Cale, Bel-nono, Samuel, Belaganahalli, Manjunatha, Belay, Desalgen, Belkharia, Jaber, Binol, Ridzki M. F., Bird, Brian, Bista, Manisha, Biswas, Pitu, Blake, Matthew, Boatemaa, Linda, Bonason, Margret, Brandful, James, Brown, Joseph, Brownstein, John, Camara, Mamadi, Camara, Salif, Chai, Daniel, Chakraborty, Debapriyo, Chale, Hannah, Chaudhary, Ashok, Chea, Sokha, Chmura, Aleksei, Goossens, Benoit, Chow, Andrew, Churchill, Carolina, Commey, Abraham, Couacy-Hymann, Emmanuel, Coulibaly, Julien Kalpy, Cranfield, Michael, Damanik, Wirda, Damdinjav, Batchullum, Danial, Norhidayah, Dasak, Peter, David, Runie, Dawson, Patrick, Dembele, Arjouma, Deme, Awa, Desmond, James, Dewantari, Arghianditya Kresno, Dhanota, Jaseet, Dhole, Tapan, Diep, Nguyen Thi, Dionkounda, Artistide, Diop, Gaye Laye, Dodd, Kimberly, Dogby, Otilia, Dorjnyam, Tumendemberel, Dosso, Mireielle, Doumbouya, Kalil, Doumbouya, Mohamed Idriss, Doyle, Megan, Dramou, Simone, Drazenovich, Tracy, Duc Ahn, Dang, Duc Luu, Bach, Duendkae, Prateep, Duoc, Vu Trong, Duong, Tran Nhu, Duong, Veasna, Dursman, Huda, Dussart, Phillipe, Ee, Tan Jun, Ekiri, Abel, El Rifay, Amira S., El Shesheny, Rabel, El Taween, Ahmed N., Emmanuel, Zena Babu, Epstein, Jonathan H., Evans, Tierra Smiley, Fahmawi, Alaa, Fahn, Simeon, Feferholtz, Yasha, Ferdous, Jinnat, Fine, Amanda, Flora, Meerjady, Fransisco, Leilani, Fui Fui, Lem, Gabourie, Taylor, Gani, Millawati, Garbo, Michael, Gardner, Nicole, Gbamele, Marie, Ge, Xingyi, Gee, Lee Heng, Genovese, Brooke, Gibson, Alexandra, Gilardi, Kirsten, Gilbert, Martin, Gillis, Amethyst, Ginsos, Andrew, Godji Gnabro, Privat, Goldstein, Tracey, Gomaa, Moktar, Gomis, Jules, Gonzalez, Kevin, Grange, Zoe, Greig, Denise, Grodus, Michael, Gueu, Kpon Kakeuma Romeo, Gutierrez, Leticia, Haba, Dan Marcelin, Hamid, Suraya, Harris, Daniel K., Hashim, Abdul Kadir Abu, Hassan, Moushumi, Hassan, Quazar Nizamuddin, He, Qun, Hemachudha, Thiravat, Henry, Helen, Herbert, Ronald, Hijazeen, Zaidoun, Hilarion, Moukala Ndolo, Hill, Rebecca, Hoa, Nguyen Thi, Horwood, Paul, Hossain, Md. Enayet, Hossain, Saddam, Htun, Moh Moh, Hu, Ben, Hughes, Tom, Hul, Vibol, Van, Vo, Hussein, Fatima, Indola, Ghislain Dzeret, Iskandriati, Diah, Islam, Md. Tarikul, Islam, Shariful, Isnaim Ismail, Mohd, Ismail, Zuhair Bani, Iyanya, Jacques, Jaimin, Joel Judson, Jambai, Amara, Japning, Jeffrine Rovie Ryan, Japrin, Alexter, Jean Louis, Frantz, Joe, Titus, Johnson, Erica, Joly, Damien, Joshi, Jyotsna, Kalengkongan, Jusuf, Kalivogui, Douokoro, Kamara-Chieyoe, Nenneh, Kamau, Joseph, Kambale Syaluha, Eddy, Kandeil, Ahmed, Kane, Yogouba, Karesh, William, Kargo, Kandeh, Kasenda, Novie, Kayali, Ghazi, Kayed, Ahmed S., Kazwala, Rudovick, Ke, Changwen, Keates, Lucy, Kebede, Nigatu, Khamphaphongphane, Bouaphanh, Kheong, Chong Chee, Kilonzo, Christopher, Koffa, Ma-Sue, Kollie, Amos G., Kondiano, Marcel Sidik, Koropo, Michel, Kouamé Kouakou, Valere, Kouassi Koffi, Eugene, Kourouma, Mariam, Koutate, Abdoulaye Ousmane, Kowel, Citra Liv, Krou, Hermann Assemien, Kumakamba, Charles, Kutkat, Omnia, Lamah, François, Lan, Nguyen Thi, Lane, Jennifer, Lange, Christian, Larmouth, Emmanuel, Le Doux, Joseph Diffo, Leasure, Elizabeth, Leasure, Katherine, LeBreton, Mat, Lee, Jimmy, Lee, Helen, Lee, Mei Ho, Leno, Amara, Li, Hongying, Liang, Eliza, Liang, Neal, Lim, Dorothy, Lipkin, W. Ian, Liu, Jun, Lo, Modou Moustafa, Lojivis, Leonoris, Long, Nguyen Van, Lucas, Ashley, Lukusa, Jean Paul, Lungay, Victor, Lushima, Shongo, Lutwama, Julius, Ma, Wenjun, Machalaba, Catherine, Maganga, Grace, Magesa, Walter Simon, Mahmoud, Sara H., Makuwa, Maria, Makweta, Asha, Mamun, Abdullah Al, Manandhar, Prajwol, Maneeorn, Patarapol, Mann, Harjeet, Maomy, Bhele, Maptue, Victorine, Mathew, Alice, Mavoungou, Yanne Vanessa, Maw, Min Thein, Mazet, Jonna, Mbala, Placide, Mbuba, Emmanuel, Mbunwe, Eric, McIver, David, Mendelsohn, Emma, Miegakanda, Valchy Bel-Bebi, Minh, Phan Quang, Mkali, Happy, Moatasim, Yassmin, Mombouli, Jean Vivien, Monagin, Corina, Montecino-Latorre, Diego, Mossoun Mossoun, Arsene, Mostafa, Ahmed, Mouiche, Moctar, Mpassi, Romain Bagamboula, Msigwa, Alphonce, Mudakikwa, Antoine, Mugok, Laura Benedict, Mulembakani, Prime, Murray, Suzan, Musa, Fakhrul Hatta, Musabimana, Pacifique, Mutura, Samson, Mwamlima, Tunu, Mwanzanilla, Mwokozi, Myaing, Tin Tin, Myat, Theingi Win, Myo Chit, Aung, N’faly, Magassouba, N’Guettia, Manzan Jean, N’télo, Anatole, Nakimera, Sylivia, Nam, Vu Sinh, Napit, Rajindra, Nathan, Senthilvel K. S. S., Navarrete-Macias, Isamara, Ndebe, Kortu M., Ndiaye, Amadou, Ndiaye, Daouda, Negash, Yohannes, Nga, Nguyen Thi Thanh, Ngay, Ipos, Ngoc, Pham Thi Bich, Niama, Fabien, Nina, Rock Aimé, Niyonzima, Schadrack, Nkom, Felix, Nkoua, Cynthia, Noordin, Noorliza, Noviana, Rachmitasari, Nwobegahay, Julius, Nziza, Julius, O’Rourke, Daniel, O’Rourke, Tammie, Obodai, Evangeline, Okello Okwir, Ricky, Olival, Kevin, Olson, Sarah, Olva, Onkirotin Dionne, Ontiveros, Victoria, Opook, Fernandes, Panchadcharam, Chandrawathani, Pandit, Pranav, Parra, Henri-Joseph, Phuc, Tran Minh, Phuong, Nguyen Thanh, Poultolnor, Jackson Y., Pradhan, Saman, Preston, Eunah Cho, Pruvot, Mathieu, Purevtseren, Dulam, Puri, Dhiraj, Quang, Le Tin Vinh, Rachmitasari, Novie, Rahman, Kaisar, Rahman, Mizanur, Rahman, Mohammed Ziaur, Rahman, Mustafizur, Ramirez, Diana, Randhawa, Nistara, Raut, Samita, Rosario, Joseph, Ross, Albert, Ross, Noam, Rostal, Melinda, Roualdes, Pamela, Rubin, Eddy, Rumi, Aftab Uddin, Rundi, Christina, Sackie, Melkor, Sajali, Zikankuba, Samuels, Sandra G, Sango, Mathias, Saptu, Ammar Rafidah, Saraka, Daniel N’guessan, Sartee, Alvis A., Sayandouno, Sia Alida, Seck, Mame Cheikh, Sedor, Victoria, Sharma, Ajay Narayan, Sharminie, Velsri, Shehata, Mahmoud M., Sheikh, Gafur, Shi, Zhengli, Shiilegdamba, Enkhtuvshin, Shrestha, Bishwo, Shrestha, Rima, Sidibey, Mohammed, Silithammavong, Soubanh, Simon, Daniel, Sion, Emilly, Sipangkui, Symphorosa, Sitam, Frankie Thomas, Smith, Brett, Smith, Bridgette, Smith, Woutrina, Sodnom, Batsikhan, Ssebide, Benard, Suleiman, Maria, Sullivan, Ava, Sungif, Nur Amirah, Suu-Ire, Richard, Sy, Mouhamed, Takuo, Jean Michel, Talafha, Hani, Tamoufe, Ubald, Tetteh, Emmanuel, Than Toe, Aung, Thanda, Lanash, Thanh Long, Ngo, Thein, Wai Zin, Theppangna, Watthana, Thinh, Nguyen Duc, Thuy, Hoang Bich, Thuy, Nguyen Thu, Togami, Eri, Tolno, Moise Bendoua, Tolovou, Kevin, Topani, Rahmat, Tremeau-Bravard, Alexandre, Trupin, Ian, Tumushime, Jean Claude, Tun, Kyaw Yan Naing, Turay, Joseph, Uddin, Helal, Uhart, Marcela, Ureda, Nicole, Valitutto, Marc, Verasahib, Khebir, Vodzak, Megan, Wacharapluesadee, Supaporn, Wahad, Mohammad Yuery Wazlan Abdul, Watson, Brooke, Wells, Heather, White, Allison, Willoughby, Anna, Wiyatno, Ageng, Wolking, David, Yang, Xinglou, Yao, Lim Ming, Yombouno, Sayon, Young, Cristin, Zambrana-Torrelio, Carlos, Zeid, Zahidah Izzati, Zghoul, Ghadeer, Zhang, Libiao, Zhang, Yunzhi, Zhu, Guangjian, Zimmerman, Dawn, Zoumarou, Daba, Aguirre, Alonso, Aguirre, Luis, Akongo, Mark-Joel, Alandia Robles, Erika, Ambu, Laurentius, Ayala Aguilar, Glenda, Barcena, Luis, Barradas, Rosario, Basir, Misliah Mohamad, Bogich, Tiffany, Bounga, Gerard, Buchy, Philippe, Bunn, David, Byaruba, Denis, Cameron, Ken, Carroll, Dennis, Cavero, Nancy, Cespedes, Manuel, Che, Xiaoyu, Chiu, Charles, Chor, Kimashalen, Clements, Andrew, Dary Acevedo, Luz, de Almeida Campos, Angelica, De La Puente, Micaela, de Lamballerie, Xavier, de Paula, Catia, Delwart, Eric, Diffo Le Doux, Joseph, Doyle-Capitman, Catherine, Durigon, Edison, Fair, Joseph, Ferrer-Paris, José R., Formenty, Pierre, Galarza, Isabel, Garcia, Joel, Grard, Gilda, Greatorex, Zoe, Harris, Laurie, Hitchens, Peta, Ho, Mei, Hosseini, Parviez, In, Samath, Iñíguez, Volga, Jain, Komal, Jamaluddin, Abd. Aziz, Johnson, Christine, Jones, Kate, Joyner, Priscilla, Kaba, Serge, Kambale, Eddy, Kataregga, Abdulhameed, Kelly, Terra, Khammavong, Kongsy, Kilpatrick, A. Marm, Laimun, Samsir, Lee, Mei-Ho, LeRoy, Eric, Levinson, Jordan, Levy, Marc, Limachi, Rolando, Loh, Elizabeth, Lowenstine, Linda J., Luis Mollericona, José, Maganga, Ruth, Malakalinga, Joseph, Manhas, Melissa, Marra, Pete, Mbabazi, Rachael, Medellín, Rodrigo, Mendoza, Patricia, Miller, Sireeda, Miranda, Flavia, Mitchell, Megan, Mohamed, Ramlan, Mollard, Debbie, Morse, Stephen, Mouellet, Wivine, Moya, Isabel, Murillo, Yovanna, Murray, Kris, Muyembe Tamfum, Jean-Jacques, Nassar, Fernando, Nathan, Sen, Nsengimana, Olivier, Ogg Keatts, Lucy, Ojeda-Flore, Rafael, Okwir Okello, Ricky, Ondzie, Alain, Paweska, Janusz, Pereira, Alisa, Pereira, Victoria, Perez, Alberto, Perez, Jocelyn, Phon, Simorn, Reed, Patricia, Rejmanek, Dan, Rico, Oscar, Rivera, Rosario, Romero, Monica, Roy, Celina, Saepuloh, Uus, Schneider, Brad, Schwind, Jessica, Singhalath, Sinpakhome, Smith, Kristine, Suárez, Fabiola, Suzan, Gerardo, Thanh Nga, Nguyen Thi, Thomas, Kate, Ticona, Herminio, VanWormer, Elizabeth, Villar, Sandra, Weisman, Wendy, Westfall, Michael, Whittier, Chris, Wicker, Leanne, Wolfe, Nathan, Yang, Angela, Zariquiey, Carlos, Zhang, Shu-Yi, Zorine Nkouants, Baudelaire, Zainuddin, Zainal, Chrisman, Cara, Pabst, August, Shek, Amalhin, and Trostle, Murray

Subjects
0301 basic medicine, Behavioral risk, medicine.medical_specialty, Behavioural sciences, Disease, Community integration, Basic Behavioral and Social Science, 03 medical and health sciences, 0302 clinical medicine, Clinical Research, 2.3 Psychological, Behavioral and Social Science, Agency (sociology), medicine, 2.2 Factors relating to the physical environment, GE1-350, Aetiology, One health, Social science research, business.industry, Prevention, Research, Public health, PREDICT Consortium, Public relations, Focus group, Environmental sciences, Good Health and Well Being, 030104 developmental biology, One Health, Multi-disciplinary surveillance, social and economic factors, Public aspects of medicine, RA1-1270, Infection, Psychology, International development, business, 030217 neurology & neurosurgery
Abstract

In an effort to strengthen global capacity to prevent, detect, and control infectious diseases in animals and people, the United States Agency for International Development’s (USAID) Emerging Pandemic Threats (EPT) PREDICT project funded development of regional, national, and local One Health capacities for early disease detection, rapid response, disease control, and risk reduction. From the outset, the EPT approach was inclusive of social science research methods designed to understand the contexts and behaviors of communities living and working at human-animal-environment interfaces considered high-risk for virus emergence. Using qualitative and quantitative approaches, PREDICT behavioral research aimed to identify and assess a range of socio-cultural behaviors that could be influential in zoonotic disease emergence, amplification, and transmission. This broad approach to behavioral risk characterization enabled us to identify and characterize human activities that could be linked to the transmission dynamics of new and emerging viruses. This paper provides a discussion of implementation of a social science approach within a zoonotic surveillance framework. We conducted in-depth ethnographic interviews and focus groups to better understand the individual- and community-level knowledge, attitudes, and practices that potentially put participants at risk for zoonotic disease transmission from the animals they live and work with, across 6 interface domains. When we asked highly-exposed individuals (ie. bushmeat hunters, wildlife or guano farmers) about the risk they perceived in their occupational activities, most did not perceive it to be risky, whether because it was normalized by years (or generations) of doing such an activity, or due to lack of information about potential risks. Integrating the social sciences allows investigations of the specific human activities that are hypothesized to drive disease emergence, amplification, and transmission, in order to better substantiate behavioral disease drivers, along with the social dimensions of infection and transmission dynamics. Understanding these dynamics is critical to achieving health security--the protection from threats to health-- which requires investments in both collective and individual health security. Involving behavioral sciences into zoonotic disease surveillance allowed us to push toward fuller community integration and engagement and toward dialogue and implementation of recommendations for disease prevention and improved health security. Supplementary Information The online version contains supplementary material available at 10.1186/s42522-021-00036-9.

Published
2021
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5. Surveillance for coronaviruses in bats, Lebanon and Egypt, 2013-2015

Author

Shehata, Mahmoud M., Chu, Daniel K.W., Gomaa, Mokhtar R., AbiSaid, Mounir, Shesheny, Rabeh El, Kandeil, Ahmed, Bagato, Ola, Chan, Samuel M.S., Barbour, Elie K., Shaib, Houssam S., McKenzie, Pamela P., Webby, Richard J., Ali, Mohamed A., Peiris, Malik, and Kayali, Ghazi

Subjects
Bats -- Diseases and pests -- Research, Coronaviruses -- Genetic aspects -- Distribution -- Research, Company distribution practices, Health
Abstract

To the Editor: Coronaviruses (CoVs) in bats are genetically diverse, and evidence suggests they are ancestors of Middle East respiratory virus CoV (MERS-CoV), severe acute respiratory syndrome CoV, and human [...]

Published
2016

7. Bacterial Outer Membrane Vesicles (OMVs)-Based Dual Vaccine for Influenza A H1N1 Virus and MERS-CoV

Author

Shehata, Mahmoud M., Mostafa, Ahmed, Teubner, Lisa, Mahmoud, Sara H., Kandeil, Ahmed, Elshesheny, Rabeh, Boubak, Thamer A., Frantz, Renate, La Pietra, Luigi, Pleschka, Stephan, Osman, Ahmed, Kayali, Ghazi, Chakraborty, Trinad, Ali, Mohamed A., Mraheil, Mobarak Abu, and Institute of Medical Microbiology

Subjects
0301 basic medicine, Bacterial outer membrane vesicles, Middle East respiratory syndrome coronavirus, Influenza vaccine, viruses, Immunology, lcsh:Medicine, medicine.disease_cause, Article, Virus, Neutralization, 03 medical and health sciences, MERS-CoV, 0302 clinical medicine, Antigen, Drug Discovery, medicine, H1N1pdm, Pharmacology (medical), ddc:610, Pharmacology, biology, lcsh:R, Medical sciences Medicine, Virology, Vaccination, 030104 developmental biology, Infectious Diseases, OMVs, 030220 oncology & carcinogenesis, biology.protein, Antibody, influenza vaccine
Abstract

Vaccination is the most functional medical intervention to prophylactically control severe diseases caused by human-to-human or animal-to-human transmissible viral pathogens. Annually, seasonal influenza epidemics attack human populations leading to 290&ndash, 650 thousand deaths/year worldwide. Recently, a novel Middle East Respiratory Syndrome Coronavirus emerged. Together, those two viruses present a significant public health burden in areas where they circulate. Herein, we generated a bacterial outer membrane vesicles (OMVs)-based vaccine presenting the antigenic stable chimeric fusion protein of the H1-type haemagglutinin (HA) of the pandemic influenza A virus (H1N1) strain from 2009 (H1N1pdm09) and the receptor binding domain (RBD) of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) (OMVs-H1/RBD). Our results showed that the chimeric antigen could induce specific neutralizing antibodies against both strains leading to protection of immunized mice against H1N1pdm09 and efficient neutralization of MERS-CoV. This study demonstrate that OMVs-based vaccines presenting viral antigens provide a safe and reliable approach to protect against two different viral infections.

Published
2019
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8. Science-inspired sustainable behavior

Author

Kumar, Brijesh, Jensen, Mark Martin, Strielkowski, Wadim, Johnston, Juliet Tegan, Sharma, Vandana, Dandara, Collet, Shehata, Mahmoud M., Struett. Michelle Micarelli, Nikolaou, Athanasia, Szymanski, David W., Abdul-Ghani, Rashad, Cao, Bo, Varzinczak, Luiz H., Kerman, Bilal Ersen, Arthur, Patrick Kobina, Oda, Fernanda Suemi, Bohon, Wendy, Ellwanger, Joel Henrique, Tyner, Sam, Joseph Jordan, E., and Murphy, Colin

Subjects
Behavior, Science, Sustainable
Abstract

We asked young scientists this question: How has your awareness of science inspired you to adopt more sustainable and environmentally friendly behavior? Respondents from around the world described scientifi c concepts, images, and research from a range of fi elds that inspire them to make environmentally friendly decisions and model sustainable behavior for others, in both their personal and professional lives.

Published
2019

10. Isolation and Characterization of a Distinct Influenza A Virus from Egyptian Bats

Author

Kandeil, Ahmed, primary, Gomaa, Mokhtar R., additional, Shehata, Mahmoud M., additional, El Taweel, Ahmed N., additional, Mahmoud, Sara H., additional, Bagato, Ola, additional, Moatasim, Yassmin, additional, Kutkat, Omnia, additional, Kayed, Ahmed S., additional, Dawson, Patrick, additional, Qiu, Xueting, additional, Bahl, Justin, additional, Webby, Richard J., additional, Karesh, William B., additional, Kayali, Ghazi, additional, and Ali, Mohamed A., additional

Published
2019
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11. Systematic, active surveillance for Middle East respiratory syndrome coronavirus in camels in Egypt

Author

Ali, Mohamed A, primary, Shehata, Mahmoud M, additional, Gomaa, Mokhtar R, additional, Kandeil, Ahmed, additional, El-Shesheny, Rabeh, additional, Kayed, Ahmed S, additional, El-Taweel, Ahmed N, additional, Atea, Mohamed, additional, Hassan, Nagla, additional, Bagato, Ola, additional, Moatasim, Yassmin, additional, Mahmoud, Sara H, additional, Kutkat, Omnia, additional, Maatouq, Asmaa M, additional, Osman, Ahmed, additional, McKenzie, Pamela P, additional, Webby, Richard J, additional, and Kayali, Ghazi, additional

Published
2017
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13. Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Dromedary Camels in Africa and Middle East.

Author

Kandeil, Ahmed, Gomaa, Mokhtar, Nageh, Ahmed, Shehata, Mahmoud M., Kayed, Ahmed E., Sabir, Jamal S. M., Abiadh, Awatef, Jrijer, Jamel, Amr, Zuhair, Abi Said, Mounir, Byarugaba, Denis K., Wabwire-Mangen, Fred, Tugume, Titus, Mohamed, Nadira S., Attar, Roba, Hassan, Sabah M., Abdulaziz Linjawi, Sabah, Moatassim, Yassmin, Kutkat, Omnia, and Mahmoud, Sara

Subjects
CORONAVIRUSES, MIDDLE East respiratory syndrome, MERS coronavirus, CAMELS, VIRUS diseases
Abstract

Dromedary camels are the natural reservoirs of the Middle East respiratory syndrome coronavirus (MERS-CoV). Camels are mostly bred in East African countries then exported into Africa and Middle East for consumption. To understand the distribution of MERS-CoV among camels in North Africa and the Middle East, we conducted surveillance in Egypt, Senegal, Tunisia, Uganda, Jordan, Saudi Arabia, and Iraq. We also performed longitudinal studies of three camel herds in Egypt and Jordan to elucidate MERS-CoV infection and transmission. Between 2016 and 2018, a total of 4027 nasal swabs and 3267 serum samples were collected from all countries. Real- time PCR revealed that MERS-CoV RNA was detected in nasal swab samples from Egypt, Senegal, Tunisia, and Saudi Arabia. Microneutralization assay showed that antibodies were detected in all countries. Positive PCR samples were partially sequenced, and a phylogenetic tree was built. The tree suggested that all sequences are of clade C and sequences from camels in Egypt formed a separate group from previously published sequences. Longitudinal studies showed high seroprevalence in adult camels. These results indicate the widespread distribution of the virus in camels. A systematic active surveillance and longitudinal studies for MERS-CoV are needed to understand the epidemiology of the disease and dynamics of viral infection. [ABSTRACT FROM AUTHOR]

Published
2019
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