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8. Residue Levels of Organochlorine Pesticides in Breast Milk and Its Associations with Cord Blood Thyroid Hormones and the Offspring’s Neurodevelopment

Author

Kao, Cheng-Chih, primary, Que, Danielle E., additional, Bongo, Sayre J., additional, Tayo, Lemmuel L., additional, Lin, Yi-Hsien, additional, Lin, Chun-Wen, additional, Lin, Sheng-Lun, additional, Gou, Yan-You, additional, Hsu, Wen-Li, additional, Shy, Cherng-Gueih, additional, Huang, Kuo-Lin, additional, Tsai, Ming-Hsien, additional, and Chao, How-Ran, additional

Published
2019
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9. CT Angiography and MR Angiography in the Evaluation of Carotid Cavernous Sinus Fistula Prior to Embolization: A Comparison of Techniques

Author

Chen, Clayton Chi-Chang, Chang, Patricia Chuen-Tsuei, Shy, Cherng-Gueih, Chen, Wen-Shien, and Hung, Hao-Chun

Subjects
Adult, Male, Interventional, Adolescent, musculoskeletal, neural, and ocular physiology, Angiography, Digital Subtraction, Contrast Media, Middle Aged, Embolization, Therapeutic, Carotid-Cavernous Sinus Fistula, cardiovascular system, Image Processing, Computer-Assisted, Humans, Cavernous Sinus, Female, cardiovascular diseases, Tomography, Spiral Computed, psychological phenomena and processes, Carotid Artery, Internal, Magnetic Resonance Angiography, Aged
Abstract

BACKGROUND AND PURPOSE: This study compared CT angiography (CTA), MR angiography (MRA), and digital subtraction angiography (DSA) in elucidating the size and location of carotid cavernous sinus fistulas (CCFs) before embolization treatment. METHODS: This was a retrospective study of 53 patients with angiographically confirmed CCF. All patients underwent pre- and postcontrast-enhanced CTA and DSA, and 50 patients also underwent MRA. Two neuroradiologists rated detectability of the fistula tract as “good,” “moderate,” or “poor” in source images obtained by using each procedure. The χ(2) test was used to compare the imaging modalities with respect to their ability to detect fistulas. RESULTS: CTA did not differ significantly from DSA (P = .155), and both CTA (P = .001) and DSA (P = .007) performed significantly better than MRA in the population as a whole. Differences in performance among the methods, however, depended upon the segmental location of the fistula along the internal carotid artery (ICA). CTA and MRA were similar in detection of CCFs in patients with a fistula at segment 3. CTA significantly outperformed MRA in patients with a fistula at segment 4, who accounted for approximately half of the population. CONCLUSIONS: CTA source imaging has proved itself as useful as DSA for detecting CCFs. Of the 2 noninvasive techniques, CTA performed better than MRA in the population as a whole and in most patients whose fistula was located at segment 4 or 5 of the ICA.

Published
2005

10. Cerebral Sinovenous Thrombosis

Author

Chen, Hsian-Min, primary, Chen, Clayton Chi-Chang, additional, Tsai, Fong Y, additional, Shy, Cherng-Gueih, additional, Wu, Chen-Hoa, additional, Chen, Wen-Shien, additional, and Hung, Hao-Chun, additional

Published
2008
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11. Cerebral Sinovenous Thrombosis: Neuroimaging Diagnosis and Clinical Management

Author

Chen, Hsian-Min, Chen, Clayton Chi-Chang, Tsai, Fong Y, Shy, Cherng-Gueih, Wu, Chen-Hoa, Chen, Wen-Shien, and Hung, Hao-Chun

Abstract

Cerebral sinovenous thrombosis (CSVT) is an uncommon disorder that affects the dural venous sinus and cerebral vein. In our study, thirty-four patients were examined. Pre and/or post contrast-enhanced CT was done in 28 patients. MRI studies were done in 24 patients. 2-D TOF MR venography (MRV) and contrast-enhanced MRV (CEMRV) were done in 19 cases. Digital subtraction angiography (DSA) was done in 18 patients. Sixteen patients received systemic intravenous heparinization, and 12 received endovascular thrombolytic treatment with urokinase combined with anticoagulant therapy.Neuroimages of CSVT can be acquired by direct visualization of the thrombus within the dural sinus or by parenchymal changes secondary to venous occlusion. As there are some pitfalls to MRI in the diagnosis of CSVT, the combination of MRI and MRV is now the gold standard in the diagnosis of CSVT. Usually, accuracy can be improved by applying 2-D TOF MRV and CE MRV. Furthermore, the source image of MRV is critical in differentiating between normal sinus variations and diseased ones. DSA is the best tool for demonstrating dynamic intracranial circulation in CSVT and mostly is used for endovascular treatment.Systemic intravenous anticoagulant therapy with heparin is accepted as a first line treatment. Except for clinical manifestations after systemic heparinization, abnormal MR findings of parenchymal change can be used to determine when to initiate thrombolytic treatment. Endovascular therapy can be finished at the ante-grade flow within the dural sinus and continuous anticoagulation is sufficient to facilitate clinical improvement.Clinical suspicion and excellent neuroimaging are crucial in making the diagnosis of CSVT. Proper management with anticoagulants and/or endovascular thrombolytic therapy is mandatory in preventing propagation of the thrombosis and improving the clinical outcome.

Published
2008
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12. CT angiography and MR angiography in the evaluation of carotid cavernous sinus fistula prior to embolization: a comparison of techniques.

Author

Chen CC, Chang PC, Shy CG, Chen WS, and Hung HC

Subjects
Adolescent, Adult, Aged, Angiography, Digital Subtraction, Carotid Artery, Internal diagnostic imaging, Carotid Artery, Internal pathology, Carotid-Cavernous Sinus Fistula surgery, Carotid-Cavernous Sinus Fistula therapy, Cavernous Sinus diagnostic imaging, Cavernous Sinus pathology, Contrast Media, Female, Humans, Image Processing, Computer-Assisted, Male, Middle Aged, Carotid-Cavernous Sinus Fistula diagnosis, Embolization, Therapeutic, Magnetic Resonance Angiography, Tomography, Spiral Computed
Abstract

Background and Purpose: This study compared CT angiography (CTA), MR angiography (MRA), and digital subtraction angiography (DSA) in elucidating the size and location of carotid cavernous sinus fistulas (CCFs) before embolization treatment., Methods: This was a retrospective study of 53 patients with angiographically confirmed CCF. All patients underwent pre- and postcontrast-enhanced CTA and DSA, and 50 patients also underwent MRA. Two neuroradiologists rated detectability of the fistula tract as "good," "moderate," or "poor" in source images obtained by using each procedure. The chi(2) test was used to compare the imaging modalities with respect to their ability to detect fistulas., Results: CTA did not differ significantly from DSA (P = .155), and both CTA (P = .001) and DSA (P = .007) performed significantly better than MRA in the population as a whole. Differences in performance among the methods, however, depended upon the segmental location of the fistula along the internal carotid artery (ICA). CTA and MRA were similar in detection of CCFs in patients with a fistula at segment 3. CTA significantly outperformed MRA in patients with a fistula at segment 4, who accounted for approximately half of the population., Conclusions: CTA source imaging has proved itself as useful as DSA for detecting CCFs. Of the 2 noninvasive techniques, CTA performed better than MRA in the population as a whole and in most patients whose fistula was located at segment 4 or 5 of the ICA.

Published
2005

13. MR imaging of an infiltrating spinal epidural angiolipoma.

Author

Leu NH, Chen CY, Shy CG, Lu CY, Wu CS, Chen DC, and Guo TH

Subjects
Aged, Aged, 80 and over, Humans, Magnetic Resonance Imaging, Male, Neoplasm Invasiveness, Spinal Neoplasms diagnosis, Angiolipoma diagnosis, Epidural Neoplasms diagnosis, Spinal Neoplasms pathology, Thoracic Vertebrae
Abstract

Infiltrating spinal epidural angiolipoma is an uncommon benign tumor composed of mature adipose elements admixed with abnormal blood vessel, which tends to invade the surrounding soft tissue and may potentially be mistaken for an aggressive tumor. In this report, we present the MR imaging findings of a pathologically proved infiltrating spinal epidural angiolipoma that appeared largely hypointense on T1-weighted images and enhanced strongly with IV injection of contrast medium, features that suggested a malignant tumor.

Published
2003

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