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15 results on '"Sun, Qi-Man"'

1. Macro CD5L+ deteriorates CD8+T cells exhaustion and impairs combination of Gemcitabine-Oxaliplatin-Lenvatinib-anti-PD1 therapy in intrahepatic cholangiocarcinoma

Author

Lu, Jia-Cheng, Wu, Lei-Lei, Sun, Yi-Ning, Huang, Xiao-Yong, Gao, Chao, Guo, Xiao-Jun, Zeng, Hai-Ying, Qu, Xu-Dong, Chen, Yi, Wu, Dong, Pei, Yan-Zi, Meng, Xian-Long, Zheng, Yi-Min, Liang, Chen, Zhang, Peng-Fei, Cai, Jia-Bin, Ding, Zhen-Bin, Yang, Guo-Huan, Ren, Ning, Huang, Cheng, Wang, Xiao-Ying, Gao, Qiang, Sun, Qi-Man, Shi, Ying-Hong, Qiu, Shuang-Jian, Ke, Ai-Wu, Shi, Guo-Ming, Zhou, Jian, Sun, Yi-Di, and Fan, Jia

Published
2024
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5. CTLA-4 Synergizes With PD1/PD-L1 in the Inhibitory Tumor Microenvironment of Intrahepatic Cholangiocarcinoma

Author

Guo, Xiao-Jun, primary, Lu, Jia-Cheng, additional, Zeng, Hai-Ying, additional, Zhou, Rong, additional, Sun, Qi-Man, additional, Yang, Guo-Huan, additional, Pei, Yan-Zi, additional, Meng, Xian-Long, additional, Shen, Ying-Hao, additional, Zhang, Peng-Fei, additional, Cai, Jia-Bin, additional, Huang, Pei-Xin, additional, Ke, Ai-Wu, additional, Shi, Ying-Hong, additional, Zhou, Jian, additional, Fan, Jia, additional, Chen, Yi, additional, Yang, Liu-Xiao, additional, Shi, Guo-Ming, additional, and Huang, Xiao-Yong, additional

Published
2021
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8. Plasma MicroRNA Panel Predicts Early Tumor Recurrence in Patients with Hepatocellular Carcinoma after Liver Transplantation

Author

Huang, Ao, primary, Guo, De-Zhen, additional, Wang, Yu-Peng, additional, Yang, Guo-Huan, additional, Sun, Qi-Man, additional, Zhang, Xin, additional, He, Yi-Feng, additional, Song, Kang, additional, Huang, Xiao-Wu, additional, Yang, Xin-Rong, additional, Fan, Jia, additional, Zhou, Jian, additional, and Hu, Jie, additional

Published
2021
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10. Distinct PD-L1/PD1 Profiles and Clinical Implications in Intrahepatic Cholangiocarcinoma Patients with Different Risk Factors

Author

Lu, Jia-Cheng, primary, Zeng, Hai-Ying, additional, Sun, Qi-Man, additional, Meng, Qing-Nan, additional, Huang, Xiao-Yong, additional, Zhang, Peng-Fei, additional, Yang, Xuan, additional, Peng, Rui, additional, Gao, Chao, additional, Wei, Chuan-Yuan, additional, Shen, Ying-Hao, additional, Cai, Jia-Bing, additional, Dong, Rui-Zhao, additional, Shi, Ying-Hong, additional, Sun, Hui-Chuan, additional, Shi, Yujiang G., additional, Zhou, Jian, additional, Fan, Jia, additional, Ke, Ai-Wu, additional, Yang, Liu-Xiao, additional, and Shi, Guo-Ming, additional

Published
2019
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11. Long non-coding RNA 00607 as a tumor suppressor by modulating NF-κB p65/p53 signaling axis in hepatocellular carcinoma

Author

Sun, Qi-Man, primary, Hu, Bo, additional, Fu, Pei-Yao, additional, Tang, Wei-Guo, additional, Zhang, Xin, additional, Zhan, Hao, additional, Sun, Chao, additional, He, Yi-Feng, additional, Song, Kang, additional, Xiao, Yong-Sheng, additional, Sun, Jian, additional, Xu, Yang, additional, Zhou, Jian, additional, and Fan, Jia, additional

Published
2018
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14. Genetic Variations in Plasma Circulating DNA of HBV-Related Hepatocellular Carcinoma Patients Predict Recurrence after Liver Transplantation

Author

Hu, Jie, primary, Wang, Zheng, additional, Fan, Jia, additional, Dai, Zhi, additional, He, Yi-Feng, additional, Qiu, Shuang-Jian, additional, Huang, Xiao-Wu, additional, Sun, Jian, additional, Xiao, Yong-Sheng, additional, Song, Kang, additional, Shi, Ying-Hong, additional, Sun, Qi-Man, additional, Yang, Xin-Rong, additional, Shi, Guo-Ming, additional, Yu, Lei, additional, Yang, Guo-Huan, additional, Ding, Zhen-Bin, additional, Gao, Qiang, additional, Tang, Zhao-You, additional, and Zhou, Jian, additional

Published
2011
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15. Capecitabine inhibits postoperative recurrence and metastasis after liver cancer resection in nude mice with relation to the expression of platelet-derived endothelial cell growth factor.

Author

Zhou J, Tang ZY, Fan J, Wu ZQ, Ji Y, Xiao YS, Shi YH, Li XM, Sun QM, Liu YK, and Ye SL

Subjects
Animals, Capecitabine, Carcinoma, Hepatocellular metabolism, Carcinoma, Hepatocellular prevention & control, Fluorouracil analogs & derivatives, Humans, Liver Neoplasms, Experimental metabolism, Liver Neoplasms, Experimental prevention & control, Male, Mice, Mice, Inbred BALB C, Mice, Nude, Neoplasm Metastasis drug therapy, Postoperative Care, Transplantation, Heterologous, Antimetabolites, Antineoplastic therapeutic use, Carcinoma, Hepatocellular surgery, Deoxycytidine analogs & derivatives, Deoxycytidine therapeutic use, Liver Neoplasms, Experimental surgery, Neoplasm Recurrence, Local drug therapy, Thymidine Phosphorylase metabolism
Abstract

Purpose: This study was to investigate the effect of capecitabine on recurrent tumor and metastasis after curative resection of liver cancer, xenograft of a highly metastatic human hepatocellular carcinoma (HCC) tumor (LCI-D20), with special reference to the expression of platelet-derived endothelial cell growth factor (PD-ECGF)., Experimental Design: LCI-D20 and LCI-D35 (a low metastatic human HCC model) liver tumors were orthotopically implanted in 96 nude mice and divided into a treatment group (24 LCI-D20 mice and 24 LCI-D35 mice) and a prevention group (48 LCI-D20 mice). In the prevention group, curative resection of liver tumors was done 10 days after the orthotopic implantation of LCI-D20 tumor. Arabic gum (control), 5-fluorouracil (5-FU), and capecitabine were administrated respectively to all of the 96 mice., Results: In the treatment group, tumor volume was 468 +/- 138, 442 +/- 81, and 240 +/- 119 mm3 (P<0.01) in the control, 5-FU, and capecitabine subgroups, respectively, in LCI-D20 mice, whereas it was 168 +/- 35, 164 +/- 23, and 144 +/- 21 mm3 (P>0.05), respectively, in LCI-D35 mice. In the prevention group, incidence of liver recurrence in the control, 5-FU, and capecitabine subgroups was 100, 100, and 50%; lung metastasis being 100, 100, and 17%; and life span being 31 +/- 5, 37 +/- 5, and 77 +/- 19 days, respectively. PD-ECGF was highly expressed in HCC and its metastatic tissues in LCI-D20 mice and hardly expressed in HCC tissues in LCI-D35 mice., Conclusions: Capecitabine inhibits tumor growth and metastatic recurrence after resection of HCC in highly metastatic nude mice model. The effect of capecitabine may be attributed to the high expression of PD-ECGF in tumors.

Published
2003

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