105 results on '"Tenenbaum T"'
Search Results
2. Streptococcus agalactiae invasion of human brain microvascular endothelial cells is promoted by the laminin-binding protein: O100
- Author
-
Tenenbaum, T., Spellerberg, B., Adam, R., Vogel, M., Kim, K. S., and Schroten, H.
- Published
- 2007
3. Antibiotika und antibakterielle Chemotherapeutika
- Author
-
DGPI - Deutsche Gesellschaft für Pädiatrische Infektiologie, Berner, Reinhard, Bialek, Ralf, Forster, Johannes, Härtel, Christoph, Heininger, Ulrich, Huppertz, Hans-Iko, Liese, Johannes G, Nadal, David, Simon, Arne, DGPI - Deutsche Gesellschaft für Pädiatrische Infektiologie, ( ), Berner, R ( Reinhard ), Bialek, R ( Ralf ), Forster, J ( Johannes ), Härtel, C ( Christoph ), Heininger, U ( Ulrich ), Huppertz, H ( Hans-Iko ), Liese, J G ( Johannes G ), Nadal, D ( David ), Simon, A ( Arne ), Berner, R, Berger, C, Hübner, J, Simon, A, Tenenbaum, T, DGPI - Deutsche Gesellschaft für Pädiatrische Infektiologie, Berner, Reinhard, Bialek, Ralf, Forster, Johannes, Härtel, Christoph, Heininger, Ulrich, Huppertz, Hans-Iko, Liese, Johannes G, Nadal, David, Simon, Arne, DGPI - Deutsche Gesellschaft für Pädiatrische Infektiologie, ( ), Berner, R ( Reinhard ), Bialek, R ( Ralf ), Forster, J ( Johannes ), Härtel, C ( Christoph ), Heininger, U ( Ulrich ), Huppertz, H ( Hans-Iko ), Liese, J G ( Johannes G ), Nadal, D ( David ), Simon, A ( Arne ), Berner, R, Berger, C, Hübner, J, Simon, A, and Tenenbaum, T
- Published
- 2018
4. Haemophilus-influenzae-Infektionen
- Author
-
DGPI - Deutsche Gesellschaft für Pädiatrische Infektiologie, Berner, Reinhard, Bialek, Ralf, Forster, Johannes, Härtel, Christoph, Heininger, Ulrich, Huppertz, Hans-Iko, Liese, Johannes G, Nadal, David, Simon, Arne, DGPI - Deutsche Gesellschaft für Pädiatrische Infektiologie, ( ), Berner, R ( Reinhard ), Bialek, R ( Ralf ), Forster, J ( Johannes ), Härtel, C ( Christoph ), Heininger, U ( Ulrich ), Huppertz, H ( Hans-Iko ), Liese, J G ( Johannes G ), Nadal, D ( David ), Simon, A ( Arne ), Tenenbaum, T, Berner, R, Berger, C, Vogel, U, DGPI - Deutsche Gesellschaft für Pädiatrische Infektiologie, Berner, Reinhard, Bialek, Ralf, Forster, Johannes, Härtel, Christoph, Heininger, Ulrich, Huppertz, Hans-Iko, Liese, Johannes G, Nadal, David, Simon, Arne, DGPI - Deutsche Gesellschaft für Pädiatrische Infektiologie, ( ), Berner, R ( Reinhard ), Bialek, R ( Ralf ), Forster, J ( Johannes ), Härtel, C ( Christoph ), Heininger, U ( Ulrich ), Huppertz, H ( Hans-Iko ), Liese, J G ( Johannes G ), Nadal, D ( David ), Simon, A ( Arne ), Tenenbaum, T, Berner, R, Berger, C, and Vogel, U
- Published
- 2018
5. The Increase in Invasive Bacterial Infections With Respiratory Transmission in Germany, 2022/2023.
- Author
-
Singer, R., Abu Sin, M., Tenenbaum, T., Toepfner, N., Berner, R., Buda, S., Schlaberg, J., Schnfeld, V., Reinacher, U., van der Linden, M., Claus, H., Lm, T. T., Schneider, M., Noll, I., Haller, S., and Laer, A. v.
- Abstract
Background: In late 2022, health care institutions in Germany reported an unusual number of severe, invasive bacterial infections in association with a high incidence of viral respiratory infections. Methods: We analyzed routine data on invasive infections due to Haemophilus influenzae, Neisseria meningitidis, Staphylococcus aureus, Streptococcus pneumoniae, and Streptococcus pyogenes (20172023) from a voluntary, laboratory-based surveillance system involving continuously participating facilities providing diagnostic routine data that cover approximately one-third of the German population. Results: In the first quarter (Q1) of 2023, the number of invasive S. pyogenes isolates rose by 142% (n =837 vs. mean Q1/20172019=346, 95% CI [258; 434]), while the number of H. influenzae isolates rose by 90% (n =209 in Q1/2023 vs. mean Q1/20172019=110, 95% CI [79; 142]), compared to pre-pandemic seasonal peak values. The number of invasive S. pneumoniae isolates was high in two quarters (n =1732 in Q4/2022 und Q1/2023). Adults aged 55 and older and children younger than 5 years were most affected by invasive H. influenzae, S. pneumoniae, and S. pyogenes infections. N. meningitidis was most commonly found in children under age 5. Conclusion: The reason for the marked rise in invasive bacterial infections may be an increased circulation of respiratory pathogens and elevated susceptibility in the population after relaxation of the measures taken to prevent COVID-19 infection. Coinfections with respiratory viruses may have reinforced this effect. We recommend continuous surveillance, preventive measures such as raising awareness about invasive bacterial diseases, and vaccination as recommended by the German Standing Committee on Vaccinations (STIKO). [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
6. Virale Mono- und Koinfektionen bei Kindern mit infektassoziiertem Krampfanfall
- Author
-
Gress, K, Adams, O, Schroten, H, Tenenbaum, T, Gress, K, Adams, O, Schroten, H, and Tenenbaum, T
- Published
- 2016
7. Identifizierung von Subklassen spezifischer Mechanismen für CD8+ versus CD4+ T-Zell Migration über die Blut-Hirn-Schranke im Rahmen von Neuroinflammation (DGPI-Forschungsstipendium 2012)
- Author
-
Rudolph, H, Kloppstein, A, Blatti, C, Schroten, H, Tenenbaum, T, Lyck, R, Engelhardt, B, Rudolph, H, Kloppstein, A, Blatti, C, Schroten, H, Tenenbaum, T, Lyck, R, and Engelhardt, B
- Published
- 2016
8. Septische Arthritis durch Moraxella lacunata bei einem 9 Monate alten Kind
- Author
-
Weichert, S., Schroten, H., Durst, A., and Tenenbaum, T.
- Subjects
ddc: 610 ,610 Medical sciences ,Medicine - Abstract
Einleitung: Die Ursache, Epidemiologie, Diagnostik und Therapie von osteoartikulären Infektionen hat sich in den letzten Jahren deutlich gewandelt. Die septische Arthritis ist aber nach wie vor eine seltene Erkrankung im Kindesalter. Als häufige Erreger finden sich Staphylococcus areus und[for full text, please go to the a.m. URL], 21. Jahrestagung der Deutschen Gesellschaft für Pädiatrische Infektiologie (DGPI)
- Published
- 2013
9. Anaphylaxie nach Impfungen - Ergebnisse der ESPED Studie 2008-2010
- Author
-
Weichert, S., Schroten, H., and Tenenbaum, T.
- Subjects
ddc: 610 ,610 Medical sciences ,Medicine - Abstract
Einleitung: Anaphylaxie ist die schwerste Form einer akuten immunologischen Reaktion und ist gekennzeichnet durch die Beteiligung mehrerer Organsysteme und ein rasches Voranschreiten der Symptome. Potentielle Bedeutung bezieht Anaphylaxie als Komplikation nach Impfungen u.a. dadurch, dass im Falle einer[for full text, please go to the a.m. URL], 21. Jahrestagung der Deutschen Gesellschaft für Pädiatrische Infektiologie (DGPI)
- Published
- 2013
10. Konnatale Toxoplasmose und Sphärozytose bei einem Frühgeborenen
- Author
-
Papandreou, T, Schaut, C, Hien, S, Schaible, T, Schroten, H, and Tenenbaum, T
- Subjects
ddc: 610 ,610 Medical sciences ,Medicine - Abstract
Hintergrund: Die konnatale Toxoplasmose, verursacht durch das Protozoon Toxoplasma gondii, stellt eine ernsthafte Bedrohung für den Feten dar. Die Inzidenz liegt in Europa bei ca. 1-15/10.000 Lebendgeburten. Fallbericht: Wir berichten über ein weibliches, eutrophes Frühgeborenes[for full text, please go to the a.m. URL], 20. Jahrestagung der Deutschen Gesellschaft für Pädiatrische Infektiologie (DGPI)
- Published
- 2012
- Full Text
- View/download PDF
11. Aseptische Milzabzesse bei einer 15-jährigen Patientin – potentielle Rolle von Anaerobiern
- Author
-
Jordan, A, Dehmel, M, Adam, R, Sertdemir, M, Neff, W, Schroten, H, and Tenenbaum, T
- Subjects
ddc: 610 ,610 Medical sciences ,Medicine - Abstract
Einleitung: Abszesse innerhalb des Milzparenchyms stellen eine seltene Erkrankungsentität bei Kindern dar. Sie werde häufig durch infektiöse Erreger wie Anaerobier oder Pilze hervorgerufen. Risikofaktoren sind intraabdominelle Infektionen oder eine Immunsuppression. Aseptische Milzabszesse[for full text, please go to the a.m. URL], 20. Jahrestagung der Deutschen Gesellschaft für Pädiatrische Infektiologie (DGPI)
- Published
- 2012
- Full Text
- View/download PDF
12. Atypisches Kawasaki-Syndrom mit ausgeprägter Hepatitis und Gastroenteritis als Hauptsymptome
- Author
-
Dehmel, M, Jordan, A, Tenenbaum, T, and Schroten, H
- Subjects
ddc: 610 ,610 Medical sciences ,Medicine - Abstract
Hintergrund: Das Kawasaki-Syndrom ist eine häufige Erkrankung im frühen Kindesalter und kann bei später Diagnosestellung und Behandlungsbeginn einen komplikationsreichen Verlauf, insbesondere mit Bildung von Koronaraneurysmen, nehmen. Nicht selten ist die klinische Präsentation atypisch.[for full text, please go to the a.m. URL], 20. Jahrestagung der Deutschen Gesellschaft für Pädiatrische Infektiologie (DGPI)
- Published
- 2012
- Full Text
- View/download PDF
13. Untersuchungen zur Wirtszellantwort nach Infektion mit Neisseria meningitidis im humanen Modell der Blut-Liquor Schranke
- Author
-
Borkowski, J, Steinmann, U, Tenenbaum, T, Schroten, H, and Schwerk, C
- Subjects
ddc: 610 ,610 Medical sciences ,Medicine - Abstract
Hintergrund: Im Verlauf einer bakteriellen Meningitis kann der humanspezifische Erreger Neisseria meningitidis (Nm) in das ZNS eindringen, indem er die Blut-Liquor-Schranke (BLS) überwindet, die durch die Epithelzellen des „choroid plexus“ (CP) gebildet wird. Wirtszellrezeptoren, [for full text, please go to the a.m. URL], 20. Jahrestagung der Deutschen Gesellschaft für Pädiatrische Infektiologie (DGPI)
- Published
- 2012
- Full Text
- View/download PDF
14. Die Transmigration von humanen neutrophilen Granulozyten und Monozyten über die Epithelzellen der humanen Blut-Liquor-Schranke nach einer bakteriellen Infektion in vitro
- Author
-
Steinmann, U, Borkowski, J, Schroten, H, Schwerk, C, and Tenenbaum, T
- Subjects
ddc: 610 ,610 Medical sciences ,Medicine - Abstract
Hintergrund: Bei der Entwicklung einer bakteriellen Meningitis müssen Bakterien die Epithelzellen der Blut-Liquor-Schranke (BLS) oder die Endothelzellen der Blut-Hirn-Schranke überwinden. Nach der Invasion der Bakterien, werden Leukozyten zum Ort der Infektion rekrutiert und schütten [for full text, please go to the a.m. URL], 20. Jahrestagung der Deutschen Gesellschaft für Pädiatrische Infektiologie (DGPI)
- Published
- 2012
- Full Text
- View/download PDF
15. Prevalence of antibodies against influenza A and B viruses in children in Germany, 2008 to 2010
- Author
-
Sauerbrei, A, primary, Langenhan, T, additional, Brandstädt, A, additional, Schmidt-Ott, R, additional, Krumbholz, A, additional, Girschick, H, additional, Huppertz, H, additional, Kaiser, P, additional, Liese, J, additional, Streng, A, additional, Niehues, T, additional, Peters, J, additional, Sauerbrey, A, additional, Schroten, H, additional, Tenenbaum, T, additional, Wirth, S, additional, and Wutzler, P, additional
- Published
- 2014
- Full Text
- View/download PDF
16. Septische Arthritis durch Moraxella lacunata bei einem 9 Monate alten Kind
- Author
-
Weichert, S, Schroten, H, Durst, A, Tenenbaum, T, Weichert, S, Schroten, H, Durst, A, and Tenenbaum, T
- Published
- 2013
17. Anaphylaxie nach Impfungen - Ergebnisse der ESPED Studie 2008-2010
- Author
-
Weichert, S, Schroten, H, Tenenbaum, T, Weichert, S, Schroten, H, and Tenenbaum, T
- Published
- 2013
18. Bakterielle Meningitis, Hirnabszess und intrakraniales Empyem
- Author
-
Berner, R, Bialek, R, Borte, M, Nadal, D, et al, Berner, R ( R ), Bialek, R ( R ), Borte, M ( M ), Nadal, D ( D ), et al, ( ), Schroten, H, Adam, R, Berger, C, Rüggeberg, J, Schaad, U B, Tenenbaum, T, Berner, R, Bialek, R, Borte, M, Nadal, D, et al, Berner, R ( R ), Bialek, R ( R ), Borte, M ( M ), Nadal, D ( D ), et al, ( ), Schroten, H, Adam, R, Berger, C, Rüggeberg, J, Schaad, U B, and Tenenbaum, T
- Published
- 2013
19. Enteroviren fördern die Transmigration von T-Lymphozyten durch die humane Blut-Liquor-Schranke in vitro
- Author
-
Schneider, H, Weber, CE, Schöller, J, Steinmann, U, Schwerk, C, Findeisen, P, Dörries, R, Schroten, H, Tenenbaum, T, Schneider, H, Weber, CE, Schöller, J, Steinmann, U, Schwerk, C, Findeisen, P, Dörries, R, Schroten, H, and Tenenbaum, T
- Published
- 2012
20. Die Rolle von InlA und InlB bei der Invasion von Listeria monocytogenes in einem humanen Modell der Blut-Liquor-Schranke
- Author
-
Gründler, T, Tenenbaum, T, Schroten, H, Schwerk, C, Gründler, T, Tenenbaum, T, Schroten, H, and Schwerk, C
- Published
- 2012
21. Hirnabszess und intrakraniales Epyem
- Author
-
Scholz, H, Belohradsky, B H, Bialek, R, Heininger, U, Kreth, H W, Roos, R, Scholz, H ( H ), Belohradsky, B H ( B H ), Bialek, R ( R ), Heininger, U ( U ), Kreth, H W ( H W ), Roos, R ( R ), Berger, C, Schroten, H, Adam, R, Noack, R, Schaad, U B, Tenenbaum, T, Scholz, H, Belohradsky, B H, Bialek, R, Heininger, U, Kreth, H W, Roos, R, Scholz, H ( H ), Belohradsky, B H ( B H ), Bialek, R ( R ), Heininger, U ( U ), Kreth, H W ( H W ), Roos, R ( R ), Berger, C, Schroten, H, Adam, R, Noack, R, Schaad, U B, and Tenenbaum, T
- Published
- 2009
22. Streptococcus agalactiae invasion of human brain microvascular endothelial cells is promoted by the laminin-binding protein Lmb
- Author
-
TENENBAUM, T, primary, SPELLERBERG, B, additional, ADAM, R, additional, VOGEL, M, additional, KIM, K, additional, and SCHROTEN, H, additional
- Published
- 2007
- Full Text
- View/download PDF
23. Acute Hemorrhagic Pericarditis in a Child with Pneumonia Due to Chlamydophila pneumoniae
- Author
-
Tenenbaum, T., primary, Heusch, A., additional, Henrich, B., additional, MacKenzie, C. R., additional, Schmidt, K. G., additional, and Schroten, H., additional
- Published
- 2005
- Full Text
- View/download PDF
24. Tonsillectomy in children.
- Author
-
Stuck BA, Windfuhr JP, Genzwürker H, Schroten H, Tenenbaum T, and Götte K
- Abstract
Introduction: Tonsillectomy is one of the most frequently performed surgical interventions in children. In the following, indications, preoperative evaluation, surgical techniques and postoperative complications will be discussed.Methods: Literature search in pubmed (National Library of Medicine) focusing on publications in German or English up to June 2008.Results: Indications are selected infectious diseases, upper airway obstruction for example due to tonsillar hypertrophy, and a suspected malignancy. Viral infections of the tonsils without upper airway obstruction are not an indication for surgery; in the case of acute bacterial tonsillitis, tonsillectomy is no longer recommended. In recurrent tonsillitis, tonsillectomy is only effective in specific and narrow indications. The indication for tonsillectomy in sleep disordered breathing due to adenotonsillar hypertrophy has to be based on clinical assessment, medical history, and a sleep medical history. The most relevant risk factors are obstructive sleep apnea and coagulation disorders. A standardised history regarding haemostasis and bleeding is mandatory, and is superior to routine coagulation tests. Postoperative bleeding is still the most relevant complication of tonsillectomy and is always an emergency situation.Conclusion: Tonsillectomy is one of the most frequently performed interventions in children but should be indicated with care, as life-threatening complications can occur. [ABSTRACT FROM AUTHOR]
- Published
- 2008
25. Culture models to study leukocyte trafficking across the choroid plexus
- Author
-
Tenenbaum Tobias, Steinmann Ulrike, Friedrich Corinna, Berger Jürgen, Schwerk Christian, and Schroten Horst
- Subjects
Blood-cerebrospinal fluid barrier ,Leukocyte ,Transmigration ,Meningitis ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Abstract Background A critical point during the course of central nervous system infection is the influx of leukocytes from the blood into the brain across the blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB). However, experimental in vitro models to investigate leukocyte transmigration across cultured choroid plexus epithelial cells have been lacking so far. Methods We have developed a porcine and human “inverted” culture insert system that enables leukocyte transmigration specifically from the physiologically relevant basolateral side. The models use primary porcine choroid plexus epithelial cells (PCPEC) and human choroid plexus papilloma cells (HIBCPP). As a prerequisite for a functional barrier, we optimized culture conditions in which cells are maintained in serum-containing medium until high barrier function is reached. Leukocyte transmigration through the plexus epithelial cells is analysed by three-dimensional Apotome®-imaging and electron microscopy, and the route of transmigration through the plexus epithelial cells, i.e. transcellular as well as paracellular, can be determined. Discussion As a functionally relevant porcine and human BCSFB model, PCPEC and HIBCPP respectively, offer a wide range of options for analysis of disease-related mechanisms at the choroid plexus epithelium, especially involving human pathogens. Moreover, our in vitro models facilitate the investigation of leukocyte entry into the CNS via the blood-CSF barrier.
- Published
- 2013
- Full Text
- View/download PDF
26. Candidiasis caused by Candida kefyr in a neonate: Case report
- Author
-
Weichert Stefan, Reinshagen Konrad, Zahn Katrin, Geginat Gernot, Dietz Annebärbel, Kilian Anna, Schroten Horst, and Tenenbaum Tobias
- Subjects
Children ,Candidiasis ,Non-albicans Candida species ,Urinary tract infection ,Infectious and parasitic diseases ,RC109-216 - Abstract
Abstract Background Systemic Candidia infections are of major concern in neonates, especially in those with risk factors such as longer use of broad spectrum antibiotics. Recent studies showed that also term babies with underlying gastrointestinal or urinary tract abnormalities are much more prone to systemic Candida infection. We report a very rare case of candidiasis caused by Candida kefyr in a term neonate. Case Presentation Renal agenesis on the left side was diagnosed antenatally and anal atresia postnatally. Moreover, a vesico-ureteral-reflux (VUR) grade V was detected by cystography. The first surgical procedure, creating a protective colostoma, was uneventful. Afterwards our patient developed urosepsis caused by Enterococcus faecalis and was treated with piperacillin. The child improved initially, but deteriorated again. A further urine analysis revealed Candida kefyr in a significant number. As antibiotic resistance data about this non-albicans Candida species are limited, we started liposomal amphotericin B (AMB), but later changed to fluconazole after receiving the antibiogram. Candiduria persisted and abdominal imaging showed a Candida pyelonephritis. Since high grade reflux was prevalent we instilled AMB into the child's bladder as a therapeutic approach. While undergoing surgery (creating a neo-rectum) a recto-vesical fistula could be shown and subsequently was resected. The child recovered completely under systemic fluconazole therapy over 3 months. Conclusions Candidiasis is still of major concern in neonates with accompanying risk factors. As clinicians are confronted with an increasing number of non-albicans Candida species, knowledge about these pathogens and their sensitivities is of major importance.
- Published
- 2012
- Full Text
- View/download PDF
27. Ultra late onset group B streptococcal sepsis with acute renal failure in a child with urethral obstruction: a case report
- Author
-
Freudenstein Daniela, Reinshagen Konrad, Petzold Angela, Debus Angelika, Schroten Horst, and Tenenbaum Tobias
- Subjects
Children ,urinary tract infection ,GBS ,late onset sepsis ,Medicine - Abstract
Abstract Introduction Group B streptococci are a well-known cause of early and late onset sepsis. In neonates and older children gram-negative bacteria are mostly found in urinary tract infections and urosepsis. In adults predisposing factors for group B streptococci urinary tract infection may include diabetes mellitus and chronic renal failure. Case presentation We present a rare case of a five-month-old Caucasian boy with ultra late onset urosepsis and acute renal failure caused by group B streptococci serotype V. Excretion urography showed a subvesical obstruction that consequently was surgically corrected after antibiotic treatment of the acute infection. Conclusions Group B streptococci serotype V, urogenitary tract malformations, previous hospitalization and medical interventions may be important risk factors for the development of ultra late onset Group B streptococci sepsis in non-neonates.
- Published
- 2012
- Full Text
- View/download PDF
28. Transcellular migration of neutrophil granulocytes through the blood-cerebrospinal fluid barrier after infection with Streptococcus suis
- Author
-
Quitsch Ulrike, Galla Hans-Joachim, Berger Jürgen, Schmidt M Alexander, Greune Lilo, Wolburg Hartwig, Seibt Annette, Wewer Corinna, Schwerk Christian, Schroten Horst, and Tenenbaum Tobias
- Subjects
Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Abstract Background A critical point during the course of bacterial meningitis is the excessive influx of polymorphnuclear neutrophils (PMNs) from the blood into the brain. Both paracellular and transcellular routes of leukocyte transmigration through the blood-brain barrier have been described in CNS diseases so far. Thus, we investigated the mechanism of PMN transmigration through the blood-CSF barrier under inflammatory conditions. Methods In an "inverted" Transwell culture model of the blood-CSF barrier, the zoonotic agent Streptococcus suis (S. suis) was used to stimulate porcine choroid plexus epithelial cells (PCPECs) specifically from the physiologically relevant basolateral side. Barrier function was analyzed by measuring TEER and TR-dextran-flux, and tight junction morphology was investigated by immunofluorescence. Route and mechanism of PMN transmigration were determined by immunofluorescence, electron microscopy and FACS analysis. Quantitative real time-PCR was used to determine expression levels of ICAM-1 and VCAM-1. Results Here, we show that the transmigration of PMNs through PCPECs was significantly higher after stimulation with TNFα or infection with S. suis strain 10 compared to its non-encapsulated mutant. Barrier function was not significantly affected by PMN migration alone, but in combination with S. suis infection. Tight junction and cytoskeletal actin reorganisation were also observed after stimulation with S. suis or TNFα. Most strikingly, PMNs preferentially migrated across PCPECs via the transcellular route. Extensive sequential analyses of the PMN transmigration process with Apotome®-imaging and electron microscopy revealed that paracellular migrating PMNs stop just before tight junctions. Interestingly, PMNs subsequently appeared to proceed by transcellular migration via funnel-like structures developing from the apical membrane. It is noteworthy that some PMNs contained bacteria during the transmigration process. Flow cytometric and transmigration inhibition studies with integrin-specific antibodies showed that PMN traversal is dependent on CD11b/CD18. Analysis of cell adhesion molecules in PCPECs revealed a significant increase of ICAM-1 and VCAM-1 expression after TNFα and S. suis stimulation. Conclusion Our data underline the relevance of the blood-CSF barrier as a gate for leukocyte entry into the CNS and suggest a novel transcellular migration step during the pathogenesis of bacterial meningitis.
- Published
- 2011
- Full Text
- View/download PDF
29. TNFalpha induces choroid plexus epithelial cell barrier alterations by apoptotic and nonapoptotic mechanisms.
- Author
-
Schwerk C, Rybarczyk K, Essmann F, Seibt A, Mölleken ML, Zeni P, Schroten H, and Tenenbaum T
- Abstract
The choroid plexus epithelium constitutes the structural basis of the blood-cerebrospinal fluid barrier. Since the cytokine TNFalpha is markedly increased during inflammatory diseases in the blood and the central nervous system, we investigated by which mechanisms TNFalpha induces barrier alteration in porcine choroid plexus epithelial cells. We found a dose-dependent decrease of transepithelial electrical resistance, increase of paracellular inulin-flux, and induction of histone-associated DNA fragmentation and caspase-3 activation after TNFalpha stimulation. This response was strongly aggravated by the addition of cycloheximide and could partially be inhibited by the NF-kappaB inhibitor CAPE, but most effectively by the pan-caspase-inhibitor zVAD-fmk and not by the JNK inhibitor SP600125. Partial loss of cell viability could also be attenuated by CAPE. Immunostaining showed cell condensation and nuclear binding of high-mobility group box 1 protein as a sign of apoptosis after TNFalpha stimulation. Taken together our findings indicate that TNFalpha compromises PCPEC barrier function by caspase and NF-kappaB dependent mechanisms. [ABSTRACT FROM AUTHOR]
- Published
- 2010
- Full Text
- View/download PDF
30. 40(th) EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004
- Author
-
S. Artigas, A V Dreval, Mark I. McCarthy, C Watson, Peter H. Bennett, M Quint, Y Ikeda, E Alpert, F Schiele, H Sekihara, Erik Gylfe, P Lowe, J Kuhlmann, Alain Golay, V Longo, Shahidul Alam Khan Akm., L G Mantovani, M Zawodniak-Szalapska, G Winkler, T Harrity, L Virág, U Johne, Kuo S-W., Linda C Tapsell, J Rodriguez, Michel Komajda, K Kankova, Carole A. Cull, M Sporna, E Estilles, U Ribel, M C Spruce, E Buzzigoli, T Prazak, J K McLaughlin, M K Lingohr, M Lim, F Calara, A Siebenhofer, G Meregalli, Roberto Anichini, A D Baron, R Kurashvili, P C Butler, G I Fantus, T. E. De Gooyer, Park Y-M., R. Walther, S Heinrich, Agnieszka Zawiejska, S Mukherjee, Nikolaos Papanas, G Wong, Ian D. Caterson, David M. Maahs, Shuichi Kaneko, Alexandra E. Butler, Francisco Javier Ampudia-Blasco, O N Kong, Attali J-R., C A Hedman, K Oshinyemi, Nicolle Müller, I C Cranston, N Okumus, M V Vlaiculescu, Balasubramanian Ravikumar, W W Cheatham, K Mukasa, K B Biswas, Annunziata Lapolla, Phil McEwan, G Mader, Gilles Chassot, Dragi Anevski, Werner A. Scherbaum, M Donath, C Hesselmann, R A Gandhi, David E. Moller, Ezio Bonifacio, C Garcia, V Ifandi, P Hornnes, Nieuwenhoven Fav., C Puech, S Pérez-Del-Pulgar, Kim S-R., G Hines, C Rubio Terrés, Michael Gaster, N. Hosszufalusi, A Scholze, Andrew A. Young, Stavros Liatis, F Hariri, S Tan, Paul Valensi, Allan E. Karlsen, J Kim, E. Moberg, J Kaiser, L Berman, G Nelson, A Altkrüger, P Kothare, D B Cook, S Doran, G. van Dijk, Shahnaz Shahinfar, Kim C-S., P Stahl, M Manousaki, S Sigrist, S K Lim, M. P. Stern, A Guberti, C Rezzani, J McKenney, Karl Thomaseth, Sofia Carlsson, M Julia, R Brillante, I Rubesova, T Darkow, E Matsumoto, Wendy M. Macfarlane, M Di Martino, G Bardini, Rossella Menghini, D Duhot, E Farcasiu, Annalisa Natalicchio, I Lindner, J Buvat, Christian L. Brand, Harry Dorchy, Iwona Pietrzak, Z T Luo, P Home, M Ekelund, Jesper Gromada, Kristine Færch, F Piarulli, H Kim, R Mentel, Zsuzsanna K. Zsengellér, Dullaart Rpf., Anton Luger, Thomas A. Pearson, V Manicardi, P Rösen, Feng Y-M., R Morganti, Lars Hansen, Demuth H-U., Haruo Kasai, A Shostak, Rudi Steffensen, G Taylor, Markolf Hanefeld, C Santini, E Hamaguchi, Roberto Miccoli, F Storms, M Cooper, Y Lee, Allison E. Aiello, P Smith, T Suehiro, K Treece, M Waluś, Timothy A Welborn, Simone Baltrusch, E Kontela, S Chai, J Crean, H Yokoyama, Johan G. Eriksson, Rafael Hernández Hernández, J Rodríguez-Saldaña, M P Tornero, G Formoso, D. Lovell, E Bingham, A Mylonakis, M Manteghetti, D Fedele, Antonio Martín-Duce, Ralph A. DeFronzo, D Salcedo, Kurt Højlund, Antonio Petrone, Sheu Whh., C Gutierrez, Flavia Pricci, S Kurita, Z G Abbas, M M Benedetti, Philippe A. Halban, Daniel J. Cox, O Ljungkvist, Justine Davies, J Palsgaard, Lars Sjöström, E Bosi, L Janin-Manificat, W. F. Kelly, M. Fernandez, E Colak, O V Mulyarchik, B Kronshage, F Lang, M Erfurth, Takashi Kadowaki, N Jendrike, U Walter, J Wishart, Y. Neye, D Kim, N Furuhashi, M Barsotti, D Florow, L Ke, L Borgquist, N C Jackson, Ffolliott M. Fisher, V Baskar, K Yoshioka, Bryan A. Wolf, G Chabrier, R Skoumal, Livio Luzi, H Kose, I Pharisien, B. Klein, H Winiarska, M C Johnson, L Griffiths, Nonna Kravchun, C Combe, Baptist Gallwitz, J Zdychova, L Skorda, Jorma Ilonen, W Gao, I N Steen, A Terrinoni, P D Ambery, W Kern, C M Kusminski, Cho M-H., Paolo Pozzilli, Louise G. Grunnet, E Schönle, David R Matthews, Robert W. Taylor, Y Cohen, Kim H-S., M P Eccles, N B Tutuncu, D McDowell, Richard M. Bergenstal, K Takamatsu, T Steiner, Jaan Palgi, Valdemar Grill, N Niculescu, G Federici, S Lehto, P. M. McKeigue, M Barone, Michael E. Trautmann, S Smirnov, J Mannion, M Eto, C Rousseau, M Conti, C S Ernest, Antonio Ceriello, D H Schweitzer, Jung E-D., Andreas Festa, Avijit Lahiri, A Shepelkevich, A Murro, A Kollmann, Jonathan R.S. Arch, R Landgraf, Son H-Y., I Engelsberger, E Agardh, S Rodríguez-Mulero, P J Kraml, K Lee, D. F. Du Toit, E Kim, G Fadini, Williams Ajk., Philip Home, M B Antcieferov, C Perlemoine, D Perrea, Song X-L., D Ruggieri, Krister Bokvist, Heidi Sørensen, Bilbao, G Yoshino, J P Taylor, Shen H-M., S M Furier, R Urquhart, J Wohlgelernter, Jianping Weng, T. Baba, Q Hong, C Silva, Castaigne J-P., M Felaco, X X Zhang, M Jaroň, Milla Rosengård-Bärlund, J G Papp, Toshio Miyata, Lervang H-H., Park M-K., I Kinalska, A Long, Oomen Phn., N Kogawa, Ippolita Patrizia Patera, S. Karadeniz, Dinesh Selvarajah, D S Chung, A Wensaas, Richard Imrich, M Recasens, J Ruxer, O Buchea, E Wilpart, S P Stepanenko, Le Ttd., H Ohgawara, Mariaconsuelo Valentini, A Mondok, M Peltonen, Marianne O. Larsen, K Chatzianagnostou, Agneta Ståhle, A L Ferrari, L Bordier, F Maingrette, A Matsuda, G Vukomanovic, Jakob D. Wikstrom, T Yamakita, E Gorostiaga, J Jin, B Gopalan, Heinz Drexel, S Hewitt, Rury R. Holman, C Dieterle, T L Ruchti, N Asatiani, M Sidira, A Iezzi, A J Sommerfield, D Châtenet, M L Olsen, R Bergemann, C Koehler, T L Kuraeva, B Balas, Christian Berne, E Santos-Mazo, G Smith, A Siejka, R Kožnarová, A Mattina, S Sheikh, A Adomeit, M Rasmussen, J. Fagerudd, N Busciantella Ricci, Nuria Vilarrasa, E Hammar, T L Thoms, L Aydın, Ron G. Rosenfeld, A Nikolajuk, R Gos, C L Morgan, H L Yu, D Dheelchand, S Ramrath, N Boudriga, Jerome I. Rotter, C Jahannault, W M Weston, Folke Lindgärde, M Hertlova, D Knight, A Monroy-Mayorga, E Pardini, A Chamson-Reig, B Franke, Janie McCluskey, Joseph Bryan, C Nikolopoulou, Christie M. Ballantyne, Fausto Santeusanio, L Pegoraro, M Lee, A Klimenko, S Jaiveer, K. Pettersson-Fernholm, Michael A. Nauck, A Ekbom-Schnell, G Deferrari, Riccardo Schiaffini, S. Pampanelli, Khan Aka., David Hopkins, Maija Wessman, M Kamarinos, Noh J-H., O Ebisui, K McCarroll, Jeppe Sturis, Peter Nowotny, N Gorbenko, Åke Sjöholm, David G. Maggs, A E Halseth, B Cresci, A A Ortiz-Gress, A Korakovouni, O Matejkova, C E Mogensen, C J Lin, Ramon Gomis, H Seaman, C Granier, Yang C-H., F Assah, O Sanchez, Fausto Machicao, Peter G. Morris, Alberto Ortiz, A Giardinelli, D Bracaglia, A Gonzalo, S Pavlatos, Andreas Lechner, F Canovic, L Sjolind, Allan Vaag, Birgitte Bruun Nielsen, David A. Ziegler, Vito Lampasona, R Gershoni-Baruch, A. Dei Cas, H Renz, E Mena, Matthew Waltham, Kim D-M., H Levanen, D D Mick, Valentina Alexandrovna Peterkova, E Meskhishvili, Sarah Nutland, R Bustani, John R. Lindsay, M Christoforidou, A Abicht, E Harno, K Cyganek, A Fitchet, S Neelotpol, P Nikishin, P Serradas, J Hinrichsen, M Halvorson, M Chovatia, B Voet, Jinny Willis, E Parretti, M Haslbeck, M Wellard, L Teng, Julio Wainstein, J S Fischer, K. Lalic, D Roggenland, I Gich, R Anwar, Maurizio Cassader, D Serota, X J Li, R J Schotzinger, Vilmundur Gudnason, Björn Zethelius, S A Wootton, W Andrzejewski, R Rezsohazy, R Gao, T Klimentova, T Mazurek, I Bruckner, C Dohrmann, R E James, G daSilva Xavier, Kim S-Y., A Dorca, Stuart J. Pocock, Terri J. Allen, I Giovos, P B Parab, N H Andersen, P Fotinakis, Miriam Cnop, H Lee, Norbert Tennagels, Omorodola I. Abatan, F Ailett, I. Lager, D Manzella, H Hut, Larry A. Distiller, G Lip, Lim S-K., Rong Zhang, T Tsuno, Steen Knudsen, M. Bajardi, Manuel Benito, Dai Sugimoto, Melvin J. Prince, D W Dunstan, D Rankins, K A Majali, G Ozansoy, Isabella Russo, S Uçak, G Annuzzi, R Talar-Wojnarowska, K Lange, S Neugebauer-Baba, Campbell H. Thompson, Eric Renard, P. D. Mountjoy, Z Morrison, Elizabeth A. Davis, Franco Cavallo, C Corvaja, R Antuña, Craig John Currie, H Linnebjerg, He Y-L., A J Palmer, Mariola R. Chacón, H Malinska, M. Jones, R Lichnovská, K Mandes, Paolo Tessari, T Mokhort, A Laina, H. L. Y. Chan, I Schmidt, R Banks, Richard G. IJzerman, L Ksinantova, G Setti, H Vaudry, A Gallo, V Spallone, Chen J-W., Thomas Danne, A Chong, M Hallschmid, S Aczel, S Hulme, N Islam, M Hosoi, P M Ternan, P Di Bartolo, N Bishara, T Shibasaki, Martin A. Osterhoff, Im S-S., M Jecht, T Hamaguchi, S Mattera, K Ways, Elizabeth Northam, U Rajala, Reinhard W. Holl, L Yang, S Panaiotopoulos, K Horvath, R Kluge, Thora B. Bodvarsdottir, Y Dong, Irene Alemanno, C McDougall, Reimar W. Thomsen, M Campbell, W Rabl, John Öhrvik, Yuichiro Yamada, Paola Ungaro, W Benzer, Mike Sampson, Roberto Trevisan, R G Radu, Aas A-M., P E Lobo, Ricardo Scott, S M Son, Josephine M. Forbes, T A Hillier, K L Wyne, Louis L. Nguyen, J Farmer, M H Tan, Kwon H-S., J Yang, L Sandvik, Franco Folli, A K Jenum, M Nguyen, W Pratipanawatr, A L Frederiksen, Rebecca Smith, Lee H-J., A Schäfer, C Manuelli, G S Denver, T Vukovich, B Maceira, K Matsumoto, K. Chokkalingam, Nurcan Üçeyler, P Modi, Timothy M. Morgan, S Mertens, B M Singh, Michaela Riedl, K Iso, C Cucurullo, G. F. Bottazzo, M Calvani, K Hur, J Wetzels, Kazuhiro Takahashi, Y Aso, H Stammer, M G Masding, Fitsum Guebre-Egziabher, J L González-Sánchez, L Armstrong, Alberto Maran, Peter G.F. Swift, S S Popovic, J Starczynski, E Vitacolonna, Luigi Laviola, R W Gelling, Marina Cardellini, D Barilla, Rosa de Diego Martínez, W H Landschulz, Anne Mette Rosenfalck, R K Wong, Kevin E. Schneider, K Peros, Giuseppe Nanni, F Zhang, I Rákóczi, T Iburi, M Nakhjavani, X Q Zhang, S Tournis, Per Lav Madsen, Graham A. Hitman, A. Tura, K Laubner, N D Kostic, Lawrence M. Dolan, R. Sinha Roy, J A Wagner, J. Tuomilehto, J Hauptman, M Abdel-Ghany, D Lacombe, Toralph Ruge, Johannes A Maassen, Triantafyllos Didangelos, K Sasaki, I Argüelles, Klaus Levin, C Popow, Emanuel Christ, R Chetty, L Baillet-Blanco, Jo-Ann Salmon, T Mine, James L. Trevaskis, I Franke, J Gorski, E A Andrianova, A Dayan, A Caballero, Aleksandra Gilis-Januszewska, M Yasujima, Z Kasalová, C.D.A. Stehouwer, F. K. Gorus, G A Nichols, A Glowania, David P. Strachan, P Fredlund, N. F. da Silva, P Reboldi, M Sausbier, K H Groenier, G Stuccio, N Guttman, K R Ahmed, A D Ristic, T Kapellen, J Coutcher, Aldo V. Greco, Oswald Wagner, A Zagayko, Maria Alevizaki, B B Zhang, W F Ferris, Jenny Fredriksson, Lois Jovanovic, J Hänninen, R De Giglio, Kazuo Yagui, O Potterat, P Hamliton, R E Scranton, B Mankovsky, A Stylianou, B Fellström, Abdel-Wahab Yha., M Kitagawa, Katherine L. Baldock, F R Johnson, F Baigts, S D'Addato, F J Sanz, A Mistry, S D Wise, T Pratipanawatr, U R Fölsch, James R.C. Parkinson, Claudia Sommer, C Park, F E Griffiths, M L Martí, R Demirtunc, S Taniguchi, J Lundkvist, T Siegmund, Juan Sztajzel, C Dienesch, F Baumgartner, L Scalone, T M Mckolanis, K Otake, Ullrik Pedersen-Bjergaard, T M Vriesendorp, Michael B. Wheeler, Henry Schmitt, Peter Hovind, S Lange, Stephane Roze, L. Van Gaal, B Klaproth, Anthony E. Civitarese, D Eckland, A Dagar, D F Hopkins, Kari Stefansson, C Gonzalez-Yanes, B Meyboom-de Jong, D. J. Betteridge, K Buhling, M Crepaldi, Ana M. Wägner, L Renna, L Volpe, R McBride, V Corbo, E O Brennesvik, R P Hayes, R Abdollahnia, G Viviani, C F Liew, Francisco Pérez-Bravo, Jeffrey Baron, Brian M. Frier, H H Samira, D Szentendrei, K. J. Schjoedt, W K Waldhäusl, D Gniuli, D Zou, G Tschank, V Urbančič, A L Nolan, Albertini J-P., J Malcomson, M Larbig, C Cheyssac, K Aurich, C M Kesson, S Heller, Maija E. Miettinen, R F Luco, Adrian J. Cameron, Luigi Mattiello, Z. Metelko, X E Zhang, M Parramón, I. G. Obrosova, J Fruchart, M Ilic, Björn Eliasson, Gilles Chatellier, M A Martín, D M Kendall, Holger Luthman, V F Varillas, D Maccubbin, Jang S-A., Amalia Gastaldelli, E Salzsieder, P. de Mol, A Yoshida, H D Lindner, D Gostiljac, M Just, Pan C-Y., J M Fujitaki, G Eiermann, K Bergenheim, A D Frick, A Agacdiken, K Varytimiadis, K Cseh, D A Jackson, S Calderari, Dena G. Hernandez, H M Liebich, K Min, F. de Zegher, Bernd Kulzer, K Han, Ulrich A. Müller, D Marrero, H Hatakeyama, René Koopman, Doo H-K., Petr Wohl, P. Sharp, P Forder, Thor Aspelund, N Meneveau, R M Schmülling, R Aubert, Thom Sam., H Youshikawa, M Ankelo, D Bowden, I Kelly, Frédéric Fumeron, M Sartini, Robert S. Sherwin, L Varadhan, A Criscimanna, John Betteridge, V Jelic, M Bartnik, N Lemke, B Ursø, A Bertoldo, A M Owona, H Okochi, L Pérez-Tamajó, S L Monfre, Daniel Brandhorst, K T Legg, Andries J. Smit, Veronica Sancho, Masashi Hirai, C Klein, Paul J. Thornalley, A Chaidaroglou, K Miura, B Zinman, O M Dvoynishnikova, J Plank, Jan Bolinder, C Lush, B Rubi, R Pozzilli, M Bashir, S A Shtandel, F Mosca, A Naskalska, Josef Vcelak, U Sausbier, P Cavaiani, T U Baehring, Michele Solimena, P Formisano, M Rastaldi, Bernard Thorens, J Ruzzin, E Arbit, M. Hori, Torkel B. Brismar, E Soltes Rak, A Filo, P Heinke, Matthew P. Coghlan, M Masotti, I Perevozskaya, K Ahn, I Moules, K Van Dyck, I Goldstein, Z Mathe, G Z Zhao, S Fajardo, J Taylor, S Chrul, J C Pareja, D Hadjidakis, A J Scheen, N Siddiqua, D C Cavan, R Grella, Krabbe S, H J Rochlitz, A E Hinkkanen, W Wilpshaar, Richard Stevens, M Dreyer, S Hara, X Wang, Melania Manco, D Gillen, Magalie A. Ravier, Olli Simell, John C. Lawrence, Kohnert K-D., Agardh C-D., A Berghold, L Kristensen, Grant Sfa., N Gursoy, Leif Groop, N Freemantle, Anja Schweizer, L Pala, Legros J-J., C. Di Pietro, N. Yamamoto, J Magyar, B Nikolovski, H Ikeda, D Lee, Bruce A. Buckingham, A O Wollitzer, I Kennedy, C Ernest, Neville H. McClenaghan, S Tanaka, Asimina Mitrakou, T Heinze, W Kerner, Moeenaldeen Al-Sayed, Charles Thivolet, L Klaff, A Miconi, Cristina Valeri, J. O. Christensen, K. Ekberg, A Jardine, T Endo, X Zhang, D F Child, A Kienitz, D K Seidel, H. Tada, Sylvie Abouna, Cyrus Cooper, Catherine R Chittleborough, Roberta Assaloni, S Corbi, A K Bose, K Ozawa, C Ahn, K A Deans, G Jackowski, Martin Gibson, Patrick McElduff, O A Mojiminiyi, Manuel Serrano-Ríos, O Dupuy, A L Davydov, Iwar Klimes, Sten-Anders Ivarsson, N Ichino, R Matsutomo, E R Smith, A Stefanovska, B Dehmel, K Koniavitou, E Agascioglu, M Hatazaki, J. M. Gibson, T Yada, P Ribaux, M Rupnik, K Fridell, G Scutaru, L Chugunova, Henrietta Mulnier, A Kendereski, H Lehnert, C Billi, M Sobczak, Francisco M-Mj., L K Archibald, S Sukumvanich, David B. Dunger, I. Benke, G Yillar, N Stingemore, J. M. Boavida, Y Shi, Jimmy D. Bell, L Bozzetto, Andrew J. Ahmann, E Jebens, J Keiding, Elena Henkel, Mark Fineman, J F McRae, Carol Forsblom, S Martemucci, Lourdes Ibáñez, P G Prieto, L Ringholm Nielsen, S Pratas, B von Stritzky, Julio Rosenstock, Lee K-W., J Stocks, L J Strow, I Samarguliani, L Wennekes, R Cheung, Abhishek Nag, Roberto Gambino, Y Suleymanoglu, E Murphy, T T Durck, M F Peyrot, Y Unno, Alexander Mayorov, Eleuterio Ferrannini, D. C. Rao, D Neely, H Karunajeewa, J Palmisano, Julia B. Lewis, M Ravid, G Pons, E Junca, P Vexiau, S Sailesh, D K Miloslavskiy, O N Bondarenko, U Smith, S Torri, Constantine Tsigos, Cesario Bianchi, Mattia Locatelli, D Jaquet, Virpi Lindi, M Moroi, M E Tushuizen, P Pelicci, R Scognamiglio, Pal Pacher, S M Thyssen, A Péterfalvi, Y Ho, S Guntram, L Romics, T Nakagami, Clive S. Cockram, Irina Kowalska, K Brodbeck, Gojka Roglic, J. Dörig, Lise Tarnow, Therese Tillin, A López-Alba, Martin Krššák, Moses Elisaf, S Hata, D P Snoeck, D Schmoll, O V Udovichenko, A Scaramuzza, J Paul, John H. Fuller, Nicholas Katsilambros, Michele Muggeo, Pia Ekbom, Piero Marchetti, V Melki, C Bailleau, H Stavrianos, A D'Errico, Geremia B. Bolli, Amabile Maier, Kelter A-R., Anders Green, Q J Morélis, Steffen Thiel, C Watkins, R C Cheung, A Clark, Elvira Fioriti, N Ari, Nam J-Y., Y Cottin, L G Krinelke, H Al Mohammedi, Simon C. Fleming, C Jones, Z Kerényi, Ahn Y-H., Meile M-J., P Nánási, M Graner, V Canonico, Gangnerau M-N., Hugh R. Taylor, Giovanni Sartore, A. Dejgaard, Carol Kelley, S. Ali, Stéphane Dalle, Jeffrey S. Gonzalez, Elena Šeböková, Alexander Beck, Ingo B. Leibiger, M Rosu, C Pencea, Werner Waldhäusl, Kaltenbacher M-C., R Butzer, S Thore, Adam G. Tabak, Angelo Avogaro, E Standi, Boris Kovatchev, O Bradescu, Patrizia Dentelli, A Fujita, C Verri, R Chlup, Prasad Ydm., S V Hörsten, van der Merwe M-T., D Hilliard, W Klein, D Worthley, M Udvardy, Berit R. Jensen, A D'Avanzo, J Monaghan, K P Yeo, Guivarch P-H., B Bauduceau, D Weghuber, P Tatti, J Ybarra, S Gwozdziewiczová, E Gasparini, B Saltin, Charlotte Granhall, Howard Leventhal, R Marin, M Tumiati, Cicero Afg., L Csémy, B Berger, S Mikros, D Dall'Asta, M Shahmanesh, Y G Vasiljev, F Potthoff, H S Randeva, G De Berardis, J O Logan, K Warncke, P Uitterlinden, E Rehring, K Gilmore, K Shankhdhar, V V Bojko, M Vahatalo, E A Korolyova, D Wiemann, P G Lankisch, D Hendrie, F Galtier, M Rybarczyk, Gisela Dahlquist, N N Rudovich, G Stein, A Liebl, F Tan, A Westerlund, S Gronemann, I Franklin, Jonathan A. Prince, Peter Arner, E Skliros, T. Sparre, M Vigas, Maddalena Trombetta, L. Bjerre Knudsen, A C Sima, I Dubroca, Alastair Gray, I Weets, R Ferraresi, Schauer Ujw., E. Leinonen, S Corazza, Jonathan Levy, P K Prakash, R Guzder, S. Barnhill, John Blangero, J Herreros, G. de Vries, Cheng Ptw., A Macías-Batista, K. Capito, R Thomas, G Thomas, G Boemi, Lotte Pietraszek, Pierre Fontaine, I Holme, J Smedegaard, C A Harrop, U Helwig, B Levy, A P Gribben, Hiroto Furuta, P Beckett, S Giannini, Ruth L. Coleman, Eva Fernqvist-Forbes, N Cugnardey, A Dumas, Jane Pinaire, S E Hofer, D Shimono, Erik H. Serné, Alain D. Baron, C Battista, M Tanen, M Klementova, V Adams, J Komorowski, Antonio Nicolucci, E. C. Burns, H Sydall, M G Fanara, M G Giovannitti, N Okabayashi, Magdalena Szurkowska, I A Eroshkin, M. I. J. Uusitupa, D Ma, C C Dieguez, J Sutcliffe-Goulden, A V Gaddi, Michał Arabski, Serge Halimi, Wendy C. Burns, S Seclén, H Sugano, A Vinterby, K Backx, L F Diaconu, Fernando Gomez-Peralta, O'Harte Fpm., G Lepeniotis, D Laune, H Kvasničková, N H Wallén, G Boner, G Cieślik, Robert Hermann, Paul Q. Thomas, Y Kumon, Maria Maiello, M Atkins, Kenneth A. Earle, Guowang Xu, H Y Bae, I Reynisdottir, D Perez, D E Cannon, P Fabietti, I Geronooz, J Østergaard, K J Jeitler, S Skourtis, A Zambanini, A Saemann, K Kuboki, Helen L. Lutgers, A C Thai, Arne Melander, D Pinkowski, S G Straub, S A Wolfe-Coote, A Totora, Hayley Dickinson, A Lindenmair, A Ginis, I Faturos, F Van Eylen, C Huard, F Fu, N Wang, B M Rasmussen, Angela Napoli, L Granato, Markus M. Lerch, M. Frandsen, A Lyras, Lawrence S. Phillips, J Mabley, R Goldschmeding, B K Kilhovd, W Liu, Greg Poffenberger, P Cipriano, Anna Maria Charlotte K Lindqvist, A Matsuzawa, J Wang, T Yu, M S Pepper, Lena M. Thorn, Y Sakamoto, Blanche Schwappach, Anna L. Gloyn, P Dupraz, A. M. Schmidt, M Psallas, V Tsirimbis, Carl D. Langefeld, D Sass, H E Scholtz, M. Cailleau, Lauren Julia Brown, K Phillips, M. Iezzi, C Jayawarna, Eleni Anastasiou, R Lobmann, R Lundershausen, H Fujiwara, H R Nan, I C Smith, I A Karpova, A Navazio, S Kang, T. Hansen, T Watanabe, Gang Hu, Malik Rja., T Kennedy-Martin, Ulla M Smidt, J.M. Dekker, A A Fisher, H Liu, R E Pratley, B Sun, C Fledelius, J F Raposo, R Langham, Ahn S-Y., B R Waterhouse, Shaoping Deng, W Ricart, S V Melnichenko, Henrike Sell, M. Tomalino, N Takeda, Paola Massucco, A Harlan, W Henrich, C D Byrne, R Junik, Khalid Hussain, D Pop Gorceva, Torben Hansen, C Ritterath, K Ogawa, D V Phan, Bradley S Metcalf, Robb E. Moses, Juan P. Frias, Hitoshi Ishii, C Brisard, P Wolkow, H H Maurer, Ingo Rustenbeck, Juris J. Meier, Octavian Savu, S D Lin, V B Bregovski, A Fox, S Cicala, M. Koenen, L Vignati, O de Divitiis, Constantin Ionescu-Tirgoviste, Kilian Rittig, J Song, Riccardo Candido, F Cohen-Boulakia, U Shankhdhar, P Jahan, Antonio Tiengo, E Liepinsh, C Álvarez, Sigurd Lenzen, James E. Foley, A. del Arco, M A Maitan, U Mollenhauer, M A Na, A Beha, B Aicher, Gabriele Meyer, E Sommariva, J Åman, B Gmeinhart, Theede A-M., Bjorn Bolinder, Giulio Ceolotto, S Sbrana, F Biarnes, Damini Dey, Barbara Thorand, H H Klein, Juliana C.N. Chan, L Piconi, S Gudbjornsdottir, E Bobbioni-Harsch, Joanna Polanska, Cristian Serafinceanu, S Gambardella, Olivier Huber, J D Brunzell, T Nagasawa, Loretta Vileikyte, A Szocs, H Löwel, Z Lin, Anders Juul, H Tsuneki, L Sauriol, G Siebert, Marit E. Jørgensen, K Matthies, Brian D. Green, P Jurowski, Z Gao, M Furuya, Silvia Manfrini, Efthymios Motakis, E Souvatzoglou, Qian Y-Z., Byun S-H., T Nguyen, M R Anwar, Geltrude Mingrone, B. Idzior-Walus, Mamas A. Mamas, G Scholl-Schilling, C Bittner, A E Raptis, L Laghi, Murray Stewart, M Orel, Janet M. Bryson, Chris P Gale, Åke Lernmark, A B Escorza-Domínguez, C Fuentes, A S Einarsdottir, M O Akinsola, P Maisonneuve, K S Leong, B Missler, Simona Frontoni, Con Tsalamandris, Flavio Francini, D Rouiller, B.E. de Galan, Girolama Alessandra Marfia, M Fioravanti, A E Weber, M Nargis, P Nowacki, Y Chen, B Larsen, Ruth E. Gimeno, A Wojciechowska Luźniak, R Meisterfeld, Limei Liu, A Ohashi, T Pieber, Bin Yao, G A Herman, M Pallini, R E Honkanen, H Nyblom, R Humbrecht, Takashi Tsuboi, Pinar Topsever, Monika Kellerer, J Woods, Steen Stender, C Kapitza, Sherwyn Schwartz, M Taskiran, N Hashimoto, A Jabin Gustafsson, K C Silva, I Nitz, S Dzienis-Straczkowska, H Elouil, L Sommese, Patricia A. McKinney, S Ogawa, E Carr, I Porchay, Robyn G Langham, Bruno Vergès, K H Usadel, S Sivakumaran, H M Hearnshaw, José Luis Santos, R Ishibashi, F Huq, Lebrethon M-C., Z Leshchenko, Elisabetta Torlone, A Saltiki, A Plaschke, Wolfgang Koenig, D. D'Avola, C L McTernan, Haruhiko Osawa, G Cazzetta, S J Lee, S Al Jebely, Hoogma Rpl., A Shimizu, Tack Cjj., Itamar Raz, Adrian Vella, P. B. M. de Andrade, Aguiar Lgk., Wolfgang E. Schmidt, T Wolthers, W. Gatling, T S Purewal, Philipp E. Scherer, E Heller, Stephan Gielen, Jo S-R., Monica Vedovato, L Nosek, R Ryder, G Giassakis, A Cretti, A Wajngot, T Waldhör, S Zoric, H C Lee, L Pulkkinen, L Lacey, I Tomescu, R S Patarrao, X C Liu, Lauge Schäffer, Jarkko Ustinov, Anders Thorell, K Kangawa, P J Wood, T Yeoh, Jo Satoh, G Psaras, Volker Burkart, Karin Schindler, Dario Pitocco, M Kolopp, Gabriela Roman, E Renström, M Goldberg, M Beregszaszi, S Senkel, M F Meyer, María Luisa Villanueva-Peñacarrillo, Elena Beltramo, J E Snaar, A Hayward, C Abreu-Padí, S E Vielwerth, R Krones, C C Stanciu, M Izquierdo, I Elbing, R Astorga, V I Bouloukos, P Zabielski, S Precerutti, Kang S-Y., K L Pratt, Joost H-G., Matthew L. Iorio, Naomi S. Levitt, Yutaka Seino, Peter A. Gottlieb, I Ehrén, Y Matsuyama, Jean Claude Mbanya, S Parveen, R Purvis, A Cappadona, V V Afanasyeva, K Löbner, S Del Guerra, V Valle, Victor A. Gault, M Tan, M M Budge, I Ioannidis, M Ishizawa, Castelli, D Nowak, János Rigó, Claudia Bleck, E Degli Esposti, C Tortul, M Klebach, E Schvarcz, L Pauline, D Krusova, J Csillag, Park K-G., Kaichi Kida, P Bialasiewicz, S Seeliger, B A Williams, P Mistry, T Nicer, N Ahmed, H Ohashi, Peter Achenbach, van Hessen Paw., Jesús Cancelas, E Cizmarova, D Takahashi, K Tanaka, A M Rojo Llobet, Q Chen, A J Garber, P Halban, B Brunmair, A Barthel, M R Katdare, Dominique Laude, M E Pavkov, C Leach, C M Breschi, S Okada, B Balent, Ornella Massa, Ravi K. Garg, van Loon Ljc., K Obuobie, W Moll, L Varanese, V Smejkalova, B Royer, M Roth, M Belfiglio, Chae M-K., I Kimura, Casper G. Schalkwijk, Hans-Jürgen Hedrich, Heinsbroek Acm., Jared Rutter, Ken Williams, K O Lee, A N Symeonidis, J B Brown, M Pfeuffer, W. C. Knowler, A N Barsukov, A Woods, T W Kim, Khalid Bak., Andrea Mari, David J. Pettitt, Y Tomioka, J Hochman, Mireia Mora Porta, K Pagava, Krzysztof C. Lewandowski, J Taton, T Yasaka, M Tyrberg, M Sargin, P Szenthe, R Sicree, C Abreu-Padín, Magdalena Lundgren, J Radziuk, Eili Tranheim Kase, W L Goudzwaard, Yanbing Li, E Ramos, H Monastiriotis, J Cur, S Pu, Lakka H-M., Park J-S., Fabrizio Barbetti, S. Ciani, Pavel Flachs, N C Correia, Angela A. Rivellese, F Ebara, Nicolas Musi, H van Ahlen, Helen M. Colhoun, Anna Czech, Steen B. Pedersen, N Jost, N Da Silva, J Nóvoa, Y Onuma, Anna Körner, D Michael, M Straczkowski, I. Truyen, R. Schmid, Søren Paaske Johnsen, H Koenig, B. Miranda-Palma, E Wasén, F Pervin, P Cavallo-Perin, M Niessen, E P Shavrikova, P Tarkun, M Vavlukis, H Gang, O Sánchez-Vilar, C Dalla Man, S. M. Haffner, R Eggertsen, L Pucci, F T Fiedorek, E I Mainas, H Holdass, Peter R. Shepherd, A Banu, R Lichiardopol, Lee M-K., N Zaytseva, B Gumbiner, Strotmann H-J., L Y Baranova, A Kissebah, A Pezzatini, I Kharroubi, N A Thornberry, A J Buckley, B Pontiggia, T Chen, M Ikebukuro, J Leach, C Frost, J Han, H Hashizume, G Poulsen, H Eckert, Paul Zimmet, Lee J-H., Peter E. Heding, S A Ross, Nils J. Færgeman, Giuseppe Penno, T Varbanova, H S Shon, Z Canturk, S Akahane, Noel G. Morgan, A Sener, Seronde M-E., P K Thaware, W Insull, S Forst, K E White, Christoffer Hedetoft, M R Holland, K Okamoto, F Yamagata, Markus Lassila, N Tanaka, Kristian Midthjell, R Isoaho, D A Legemate, M Motzkau, Y H Kang, A P Nescheret, J Boiko, Hemmo A. Drexhage, Gagik R Galstyan, Naim Shehadeh, Henning Beck-Nielsen, T I Justesen, O Kalter-Leibovici, T Vahlberg, M Mozdzan, G Siegert, V Dumenil, Katsumi Eguchi, J A Vazquez, Sally Hollis, H Haberland, A Souvatzoglou, M L Gavete, K. S. Nair, Katharine R. Owen, C Garcia-Rodenas, Gerald I. Shulman, Peters, H A Parkes, Y S Kim, Mats Rönnback, Isabelle Leclerc, Marie-Hélène Giroix, I D Caterson, S G Rønn, L Scionti, Silvia Pinach, Hans Christian Reinecker, Kathryn Noyes, P McTernan, C Y Tan, N. Lalic, Richard D. Carr, M. Toman, D Papazoglou, Domenico Bosco, G Lübben, F. Costanza, Tania Maffucci, Jonas Nygren, Ole Lander Svendsen, Kristin Taylor, Ugo Boggi, A Kayserilioglu, Gudmar Thorleifsson, G J Dunseath, B. Balkau, T Zieher, M Schwarts, A. R. Cobitz, P de Pablos, I Recas, Carlos Lorenzo, Pamela J. Shaw, Y Cho, C Münscher, Anna Maestroni, Milan Zdravkovic, Gerstl E-M., L L Xiu, Yoshitaka Kajimoto, A Deb, F Osaki, G Kirilov, B Staffler, Běla Bendlová, M Rebelatto, Frank Reimann, B Ø Christoffersen, S Durant, Fruchart J-C., Ravinder J. Singh, V Connolly, Q Zhang, Alexandra Kautzky-Willer, Francesco Andreozzi, N Talai Rad, V Loyková, Trampisch H-J., Stefano Menini, F. Rodríguez de Fonseca, W Hanif, H J Böhles, S Fotiadis, Philippe André, T Kubiak, T Friede, J Murin, Erwin Schleicher, Adam Garrow, M Takahashi, P Valensi, S Pappas, E Lim, D N Staroverova, C Tadgell, C Dessapt, Brittany A. Rasmussen, L Cheung, L E Porter, R Ishihara, J Ravisy, T Inukai, Christine Winzer, E M Özer, Nish Chaturvedi, Ana Chico, Ville-Petteri Mäkinen, N Bellili, Howlader, Jansson P-A., A Martella, Jan Frystyk, T Kakko, K Hershon, S Hoashi, B Nag, C Chabrolle, B Leatherdale, J. Lu, Stephen Colagiuri, C Brendel, Michael Roden, Peter Clausen, A L Macdonald, R A DeFronzo, F A VanNieuwenhoven, Sirkka Keinänen-Kiukaanniemi, Jonas J-C., Hobbs Fdr., H Uchino, S Del Prato, E Polakowska, L Shankhdhar, Hedrich H-J., S Rodriguez-Cuenca, A Schwarzmaier-D'Assie, K Fukuda, Robert H. Eckel, A. Hilding, A Rutscher, D Kerr, Junhua Li, C. Köhler, A Banaszak, Peter Lönnroth, P Wulff, M A Gruzov, Fariba Shojaee-Moradie, S Matsumoto, J P New, N Barthes, M G Leyck Dieken, Mian Li, O Ivanova, G Papalia, K A Nilsson, Parving H-H., P Merz, M. A. Schweitzer, A Morris, P. Andersen, O Tschritter, M Fitch, V Fejfarova, Elisabeth Bernroider, E C Kiawi, M de Kerdanet, Claus B. Juhl, C Taxvig, Kerstin Berntorp, Birgitte Andersen, C Coscelli, C Ktori, Norio Abiru, R Mössner, Hiroko Hirooka, Jens J. Holst, Q Dan, H F Gu, C Gimpelewicz, A Oeckinghaus, B DelBuono, J Kuroda, P Kastner, Clemens Fürnsinn, H Usui, R Mosqueda-Garcia, P De Meyts, K Yamagami, M Tóth, V Leite, H Alberti, M Meneses, Gregory Collier, E G Starostina, C Delaporte, Agostino Consoli, François Alhenc-Gelas, S Tonstad, G Schuler, J Juszczyk, G Hoefle, M Wilken, Mark A. Yorek, Volker Lodwig, G Edwards, E Catellani, Ewa Wender-Ozegowska, Kurt Hoffmann, I Markova, Steven J. Hunter, A Venkataraman, Bente Klarlund Pedersen, A Kengne, Ken K. Ong, L A Calo, M Huckova, Y Morikawa, Pierina Richiusa, D Giuffrida, Sonia Brichard, Giuseppe Paolisso, Andrew T. Hattersley, M Vankova, Jon G. Mabley, G Salvidio, M Montolio, X Yang, Barbara N. Campaigne, Ralph R. Turner, Andrew J.M. Boulton, P Johnston, S Berchtold, Roger Corder, D Ledwig, M. Di Mauro, Houweling, J H Bowker, J Hilsted, Shin D-W., B Kiran, E Esteve, A J Cameron, S Spera, Kathrin Maedler, S Tsujii, J. H. DeVries, S Cailleaux, M Walter, A Florén, R Lehtonen, Davis Tme., N Patsourakos, J. Marco, G Lepore, L Morcillo, J Burén, Paul Smits, Juraj Koska, Chung J-H., Katherine S. Elliott, Bong Soo Cha, Christian Weyer, F Montorsi, L G Søndergaard, H Horie, M Herten, N Aghamohamadzadeh, L A Scrocchi, A Oyarzún, Rutten Geh., K Yamada, M Zivkovic, R S Beifort, Lee I-K., S D Bouman, H Böhles, Dwight E. Matthews, Orville G. Kolterman, Bidda Rolin, I Shymanskyy, P Thomakos, John Strand, A Virkamäki, C M Clark, Y Tokumasa, Odusanya Pot., Joel F. Habener, Abel López-Bermejo, Anders Tengholm, D Argon, Lajoix A-D., N Aki, L Kessler, N Takahashi, A Zmysłowska, Kåre I. Birkeland, D Soon, Lars Køber, M Vaňková, Lee W-C., F Payeras-Más, C Lau, E Ramos Lopez, L Lukic, A Suehiro, Stephan J-A., I Estalella, Jørgen Jensen, Liaqat Ali, V S Dimitrijevic Sreckovic, V P Maximova, G Salietti, M Ding, Yuksel Altuntas, Chung K-D., F Kaufman, Ludwig Wagner, C Calvi, D X Gram, David G. Bruce, K Sprenger, M Schweers, D Kush, D B Panagiotakos, J. M. Currie, Luis Castaño, Dag E. Undlien, D. Haspel, A Suzuki, J Cederholm, S Garcia, L Cynober, P O'Hare, A Tsur, Christine Zimmermann, M Faimalie, V V Poltorak, S Alba, Axel Haupt, J Varga, Tetsuya Yamada, M Shoji, R H Lloyd-Mostyn, Péter Pusztai, Doney Asf., M N Gangnerau, I Shimizu, Henrik Ortsäter, F Liska, Mandeep Bajaj, H Sarui, Michal Andel, S Chiheb, Diane Barker, A. van Tol, Brigitte Reusens, I Anafaroglu, Giel Nijpels, F Bongardt, K Taxildaris, M. Orsini Federici, V A Horton, K Ota, A McCall, M Vladica, Anita M. Hennige, Karsten Müssig, A Philotheou, I Chronopoulos, N A Perrin, B Janand-Delenne, Søren S Lund, S Duarte, R Bernardi, R Holman, Safia Costes, Hubert Kolb, G J Schlömer, Rainer Lehmann, Lusson J-R., J K Malone, X I Nkomo, Lars Melholt Rasmussen, E G Chittilapilly, J Satrústegui, A M Abbatecola, M Cristini, U Hanson, María Teresa Martínez-Larrad, Frida Renström, Luigi Uccioli, A Hennige, T Akhobadze, U Raval, D J McCarty, Didac Mauricio, S Horiuchi, V V Nosikov, B Wierusz-Wysocka, K Xiang, H L Fehm, Elaine Gutierrez, S Salman, E Siekierka-Kleiser, P Martul, N Kajaia, A W Herling, Tony R. Merriman, Kirsten J. Ward, René Gross, S K Althouse, S Woodhead, Emmanuel Cosson, T Rönnemaa, T M Filiz, Jerzy Loba, S Sha, Klas Malmberg, Carlo Pesce, Jung D-S., I Majdrakova, Thomas Forst, M Schütt, Hierl F-X., A M Efanov, I Verschraegen, H B Jensen-Holm, D Deckhut, Frida Leonetti, N Selzle, G Cassetti, Jose L Mesa, G Morrison, Christian-Heinz Anderwald, C Kliebe-Frisch, J H Moffitt, P Lahm, Hiroshi Ishiguro, E. Borgo, A Keech, L Quagliaro, Thomas O. Ola, Henquin J-C., W J Sluiter, F Leprêtre, Kalliopi Kotsa, Peter Karl Jacobsen, E Sanchez-Largo, E Gaia, Daniel R. Witte, Sidsel Graff-Iversen, G Seebohm, E Cacès, R G Khalifah, W Wilson, Avan Aihie Sayer, C Raffaitin, J Gumprecht, T Lehmann, E Migliaccio, R Urrutia, E Shelestova, A V Chervonsky, Stefan Mustafa, Y Hisano, Erik A. Richter, J Miettinen, K M Gottesdiener, Gangyi Yang, D Chevenne, A Girach, P Samuelsson, Taskinen M-R., D Ciociaro, D Aydemir, Yang S-B., P De, Dongliang Zhuang, Nathan R. Hill, B V Hansen, Hideki Katagiri, M Saryusz-Wolska, G Y Gandhi, Nicholas Witt, D Berzi, B J Mejía-Pedraza, D G Burrin, R Mather, V Ashkenazi-Katalan, Y Yamasaki, G B Jensen, Emma L. Edghill, Y Wang, I J Deary, M Langenfeld, J L James, K Yozai, T Appleton, Jamal A-M., A. Di Benedetto, Yutaka Nakaya, Elin Rebecka Carlsson, Y Park, T Carpenter, Attila Bokor, Patrick Harriott, S Ait El Mkadem, B Lormeau, A Ceylan-Isık, Stefania Bandinelli, Isabel Valverde, N Brevnova, Pietro Passera, F Escrivá, J El-Din, G Ertl, Tringham, S Wakabayashi, J Soler-Soler, T Tenenbaum, Kurt Widhalm, S Yoshizumi, M Masin, L Tsibina, S Shutler, Kirsten Ohm Kyvik, Nigel J. Crowther, M C O'Neill, A N Pehlivanidis, A Kürklü, P Bouter, Savontaus M-L., Sharp Gwg., Kivelä S-L., A Krasner, E Carrasco, Ravi V. Shah, A Skytthe, P Roca, B O Boehm, Felicia Ranta, Ulrich Werner, A Shearer, D Hosaka, P Papadimitriou, C Dimosthenopoulos, L Farkas, K Short, S Futakuchi, Z Garamvölgyi, C Hohberg, B Heckmann, M S Fineman, H Akahori, Yasuhiko Iwamoto, K Hashimoto, Zhihui Zhong, S Shubeska Stratrova, G M Cvijovic, C Neumann-Haefelin, Amna Khamis, J D Betteridge, P Fratino, Itxaso Rica, L Tsutskiridze, S Nakajima, S N Koval, Paolo Brunetti, J Buithieu, A K Rasmussen, John P. New, V W Rahlfs, S Pellitero, Claude Bouchard, P D van Poelje, A Ghio, S Barcelo-Batllori, B Götz, Fernando Djs., Antonio E. Pontiroli, P Lim, M Eckhard, Norbert Stefan, L Alviggi, G A Thomson, S Bergmann, E De Amici, Elisa Pagnin, C Gatsiou, Markku Laakso, M. Massi Benedetti, Szabo, E R Trimble, H Konya, T Örn, G Valsamakis, J Zhang, S Mcintyre, H Yu, C Huang, Ken’ya Sakamoto, David A. Savage, Martin Whyte, S Vakkalanka, G C Webb, R. Reitano, D James, D Bradshaw, K G Parhofer, Napoleone Ferrara, P Boucek, Henry J. Dargie, V Artikis, R A Flett, Giovanni Anfossi, I S Simeonov, D J Drucker, A Chamson, Phillips Diw., Charlotte Malis, Bernd Schultes, M. I. Hawa, Shanta J. Persaud, S Geloneze, J Sponarova, S. Lahdenperä, Y Komatsu, B Capaldo, Wojciech Młynarski, D Brasacchio, G Allochis, H Takeda, W Doering, J Grimshaw, Ichiro Niki, D Degiannis, C Köder, Carla Iacobini, Norbert Hermanns, Voss, A Grimaldi, R. Wassmuth, L Bernardi, A. Crinò, T S Temelkova-Kurktschiev, C Nita, Michail Antsiferov, A Balini, Yoo H-J., Giovanna Oddi, A C Bossi, D. S. Harry, Á Vatay, Peter R. Flatt, M Fukumoto, Sebastio Perrini, Halfoun Vlc., R Helal, Donald C. Simonson, B L Shine, E Maltezos, J Ryskjær, H Bessho, Yoichiro Kamatani, M Veitenhansl, M Farnier, N Hole, M Abbasi, Cha B-Y., Gall M-A., M Bogatean, Amitha Gopinath, M Vettore, O Seda, V J Willey, Carl Johan Östgren, R M Parhimovich, Rennings Ajm., B G Kravitz, D Lipkin, Andrea Galgani, A Nakajima, Alvin C. Powers, J E Paiker, E Souhami, Per Hildebrandt, Charlotte Kragelund, C Lindloh, M Sasaki, Torben F. Ørntoft, Nilima Biswas, G Giani, J Lazarus, H U Janka, H Li, F Reeß, S Athanaselis, S Sankar, Carlos Hernández, A Tone, R Capani, E Biermann, C. N. Hales, Petersen Jla., M Federici, Torben Jørgensen, P Kurtzhals, Michael N. Weedon, Eva Lind Rasmussen, Rupert Beale, B Leiting, Per K. Christensen, R J Young, M J Wooddell, Guy P. Nason, Jean-François Martin, J A Ruggles, C De Natale, Renu A. Kowluru, Alexandra Schneider, M E Cerf, S Galande, V. Miselli, Romano Regazzi, I Gkioulmpasanis, D Voinovich, Susanne Ullrich, Zhao P-L., R Rabasa, W G Towers, D Cerrato, G A Nuttall, Halimi J-M., Marco Falasca, Antonio Zorzano, D Bottino, C J Mullany, Michael Alvarsson, Matthias Nauck, E Pankowska, S Bulgurlu, U Hoss, Eiji Kawasaki, Davide Lauro, Ha Kbn., Beauvieux M-C., Enzo Bonora, J Lane, H Mahtab, N. Klöting, D L Winter, Freyse E-J., G. Biemer-Daub, Cecilia Invitti, J Dabrowski, Laurence Ladrière, Catherine Born, A Hiukka, Y Inoue, M Cimmino, Y K Kim, Jeanette Kuhl, J Peiker, J Szánthó, B. Zierhut, P Blazicek, M Calbacho, L Marenah, M Zbinden, Y Nakasone, David R. Owens, P Ross, T Vilsbøll, A Šmahelová, E Boldrini, S Santos-Palacios, T Krarup, J Bonnet, Dorte Vistisen, R A Ritzel, Tsuguhito Ota, L Guja, B Chappuis, Nils Billestrup, A Grilli, Polly J. Bingley, Sabine Fischer, Kenneth Robertson, P M Bell, R Coll, Y Uchigata, A Glebocka, L Rizzo, Swangjit Suraamornkul, Egberts E-H., E Zapanti, K Oi, Hideichi Makino, N. Visalli, Häkkinen A-M., Uwe Voelker, Ian Lawrence, Marju Orho-Melander, Mary-Elizabeth Patti, K Herrmann, B Hultberg, Hoekstra Jbl., Nael Shaat, Hannele Yki-Järvinen, E Canbek, E Madarász, A Marsocci, N A Foxwell, P Sorichetti, Eva Aguilera, A Bronisz, J LaSalle, M Freeman, M S Kipnes, K Ažman-Juvan, Stefan R. Bornstein, Y Kainou, Francesca Porcellati, Bart Keymeulen, Y Takemura, Joanne Rasschaert, L Juurinen, M Broch, Paddison Cam., Jens Faber, M Sanges, R Swift, S D Luzio, T Kuchmerovska, J. De Schepper, Sabina Baumgartner-Parzer, C. Herder, Peter Rossing, C L Frost, K Kaku, Zhiguang Zhou, Thomas C. Wascher, Song B-R., S Bai, M Vázquez, B. Van der Auwera, A Pavanini, Luisa Gilardini, K S Sunnerhagen, Claes B. Wollheim, S Shinn, Christian Dina, Yoichiro Iwakura, L Thomas, K C Lasseter, J Crook, V Kraft, C. J. Bailey, E Estimes, A Jiménez, Georgeanna J. Klingensmith, G Menzinger, C Rinsch, Anna Jonsson, Masakazu Kobayashi, A Goertz, K Papatheodorou, J. Lopes de Faria, C Karasu-Yilmaz, C H Hobbs, J Behjati, R Buckingham, A Patruno, A Heinrich, L. Kalbe, A Oglesby, Y Fujita, O Zacharopoulou, P Di Fulvio, G Poggi, J Jowett, W Isley, Susumu Suzuki, M Zamaklar, A M Carter, S. Efendic, Claude Knauf, Stephen B. Williams, Wu H-S., S de Kreutzenberg, Susanne Schwenke, A Coppelli, S Maxeiner, E Stridde, M Zurawska, J. H. Fuller, P Di Tomo, D Pisarczyk-Wiza, J Dudenhausen, Robert G. Nelson, Catherine Pihoker, M F Bullano, Tuomo Rankinen, J Wada, R A Greiner, L A Tchugunova, T Okada, M Bosevski, G Dentan, S Bruce, H Rittmeier, I Peovska, B Augendre-Ferrante, Zsolt Bosnyak, H van Wasen, Peter Almgren, Lut Overbergh, Bernard R. Landau, D Schumann, Frédérique Diraison, B Dietrich, Q Zhou, Alan D. Cherrington, Ottavio Giampietro, Margaret M Band, G Brandrup-Wogsen, R Eher, N Kim, Merlin C. Thomas, V Anand, K Szosland, B Gustafson, Aina S. Lihn, Mamputu J-C., Dosch H-M., G Paragh, Robert E. Ratner, C D Kim, A Heckel, Adrian J. Bone, V G Athyros, Léopold Fezeu, M A Denke, N Karlovich, M Morgutti, N Villela, Mathias D. Brendel, Peter Krippeit-Drews, Akira Matsutani, Gyula Tamás, Ole Schmitz, Chae S-H., J T Willerson, L Galuska, A Vanoli, G Habib, Giuseppe Remuzzi, R. R. Rizza, R. Sillard, S Longhitano, Hongliang Li, Y I Karachenzev, J Denne, M Grenningloh, J Hayes, B J Goldstein, S Erdmann, A Midtgaard, D F Giannakopoulou, Dick de Zeeuw, A. Holstein, J Brązert, M Zmudzinska, R E Davis, Felipe F. Casanueva, F Huet, Stephanie A. Amiel, Y Miyake, N Hiroi, Eberhard Standl, G Sebag, Caroline Kistorp, R Jaziri, Rita Basu, M Mertl-Roetzer, Flavia Franconi, U. Di Mario, M Brammer, U Langel, Meghan L. Marré, F Garcia, G H Thoresen, Ingrid Kockum, H Gin, L Sedova, Susanne Rudberg, Martin Prázný, Diana Rubin, I Kyrou, T. J. Wilkin, A D Kriketos, E M Egido, K. Sugimoto, Janssen Pgh., E Aktas, E Rylander, M Ramazashvili, Hans-Ulrich Häring, Mackay Djg., J Skupien, Yoshihisa Nakatani, I Karádi, Jurg Ott, H Makki, A J Ló, T B Bödvarsdóttir, Timo A. Lakka, J Nerup, Anders Rasmussen Rinnov, F Assimacopoulos-Jeannet, G Beretta Anguissola, F U Rodriguez, A Garcia-España, B Neve, P Curtis, M Boldrin, E Csongradi, M E Hossain, Jürgen Kasper, Concetta Suraci, Lex M. Bouter, Z Skrivanek, H Bischoff, H Yamazaki, Nicola Jackson, Irene M Stratton, D Vogelsang, E Baranyi, Andrei I. Oprescu, X Yan, L A Resnik, A Wajman, M J Sheetz, R T Ribeiro, K Oono, Angelika Thon, A H Boss, K U Wittrup-Jensen, Nanne Kleefstra, E. Ferrari, Thomas Strack, Häring H-U., R Chow, Gabriele Perriello, R Z Timar, R Giannarelli, Y Saito, Thomas Mandrup-Poulsen, Peter Bergsten, D Raunig, A Rovira, Gunnar Sigurdsson, Z Melczer, L Gu, R Elli, C Chan, F N Wang, Carmine G. Fanelli, Thomas Illig, M Szabó, K Holtz-Neiderer, R Kominato, Nieves González, M Pfohl, D. P. Bataille, R Peter, Robert J. Heine, E Bacillo, S J Creely, D Bruttomesso, D Karagianni, I O Shymanskyy, Lüddeke H-J., D P Kurktschiev, H J Kim, K Nanjo, B R Lee, Valeriya Lyssenko, Y Hasegawa, P Langer, C Gemma, Martin E. Fernandez-Zapico, Dale S. Edgerton, C Romano, Sotirios A. Raptis, S Ishida, S Frantz, U Ott, D Simmons, Philippe Morel, P M George, E Müller, F Saleh, M. Grabert, John A. Todd, V Golozoubova, M Sikter, Carla Giordano, P K Awah, M Colding-Jorgensen, O Schoeffski, T Suda, A V Kulikovskaya, T. Lauritzen, Y Fujii, Philip G. McTernan, G V Donchenko, D P Hancock, G Renier, G Maclaine, Nita G. Forouhi, O Kolterman, S Nag, Bengt Vessby, J Genescà, D Moruzzo, P Dittrich, Aristidis Veves, M Sacco, Christopher Shaw, F Agrò, F Oana, I I Dedov, P Sergeev, A Sotiropoulos, L Moretti, Paolo Pinton, Nigel P. Jones, K Takemoto, Mary A. Cotter, Mauro Castellarin, N Roper, Peter Gæde, E Cerasi, T Hoffmann, D Gabellini, Ramzi A. Ajjan, Y Yu, Huh K-B., G I Kuntchevich, Kenichi Shikata, U Puch, Hirofumi Misu, P García, J Shen, S M Katzman, Marco Castagneto, H H Hundborg, E Kaszas, Choi M-H., R Battiato, H Shi, Y Oh, Adela Penesova, C Xipnitos, Julie C. Price, T Imamura, A M Tonkin, C Tang, A A Barros-Filho, N Chartrel, A Findlow, Z V Caparevic, Jukka Westerbacka, T Ishii, A R Vlad, O V Tuzova, M Y Gorshunska, Knut Borch-Johnsen, P Pizzocri, Bernt Lindahl, T M Wallace, H C Deng, Mikael Knip, M Shimodahira, Renato Lauro, F Zelaya, Giovanni Pacini, I Franzetti, E Karagiannis, L Wood, Wendy A. Davis, Karen J. Mcneil, M Scott, Mariella Sorcini, G Lasfargues, Philippe Froguel, Kjersti S. Rønningen, R Chotmongkol, G Zasadzinska, R Iakoubov, E Kiwanuka, M Arribas, M Schuler, K Pyörälä, H. de la Calle, Maciej Wideł, V Lowe, Ilaria Dicembrini, D H Beran, R Morikawa, K Satani, G Scarselli, Lea Bruhn Nielsen, Ahn Y-M., Aveni Haynes, Leslie Rdg., Basem M. Abdallah, K V Allen, Max Bulsara, Masataka Kusunoki, D L Duhamel, F Cipollone, Lee S-J., È Palik, A I Gladkich, T Sato, Yogish C. Kudva, L Gardete-Correia, Yoshinori Hinokio, Martin Rossmeisl, Lorena Amadio, G Gates, K Wittrup-Jensen, A Pfützner, E Tourel, V Moya-Suri, Y Imai, U Zeymer, A I Santos, J Mueller, M Lombardi, K Luz, Olga Kotova, Angela Scipioni, Bernard Portha, Reinhard G. Bretzel, Risa Ozaki, I A Katz, L Dakovska, Sampath Narayanan, T P Levchenko, M Lazarova, J Stock, D D Kim, J J Vendrell, Heikki O. Tikkanen, Ostenson C-G., Ronan Roussel, Hideaki Nakagawa, Gabriel I. Uwaifo, Paul D. Griffiths, Klaus Moeschel, Lee B-W., I Rojas, K. Staiger, Brendan T. Kinsley, J Gebel, Alessandra Bertolotto, Anthony Zagar, Domenico Accili, Richard H. Jones, A Mayorov, J M Morrell, S Soedamah-Mathu, R Obrenovic, T C Cavakcanti, J Łopatyński, Ottavia Porzio, A Barbera, R Piechatzek, Ewa Małecka-Panas, M M Mocanu, David W. Dunstan, A Y Tokmakova, Sei Hyun Baik, A De Bellis, D Kallend, D Melloul, C Rosak, S G Paule, Vicki Thallas, A Schrodter, P Roesen, G M Steil, Sabine E. Hofer, P Juretschke, D Zozulinska, Slavisa Ninkovic, V Pauvaday, D A Darko, Kim J-I., David R. Tomlinson, Fach E-M., A Papaefstathiou, L Gürtler, N Wiernsperger, J Simcox, L M Dickson, S Fujii, J Schwarz, Lars S. Rasmussen, M Trautmann, M Uzan, A Sato, Hans Günther Wahl, Tore Julsrud Berg, Kar Keung Cheng, C J Emery, M Lipsett, U Belz, Majlinda Lako, E M Gould, Rikke Due-Andersen, J N Mbanya, C Fiore, Takao Nakamura, Shield Jph., B Nadal, Lene Simonsen, Barry M. Brenner, D Fedak, J Chen, Laura E. Parton, Gao H-Y., John B. Buse, B Vialettes, M Y Guo, T Evers, Melanie J. Davies, Joan Soler, D Schmiegelt, Bárbara Angel, Hoe, B Parker, G Giovannitti, Ross Lawrenson, O Rigal, J Raastam, D S Kim, Björn Olde, Berggren P-O., Calum Sutherland, F Vittone, A Gauthey, A. M. Wagner, Paul Czernichow, Arturo Rosso, A Peter, J Hřebíček, V Martínek, B Jardin, A Fiorito, M V Trigo, S Bassan, N R Busciantella, C Turpini, G Seghieri, R Gelisio, K Nakanishi, D Pittasch, A Kamaratos, Irminger J-C., Monika Cahova, Y. Miyazaki, D V Coppini, Avierinos J-F., Erifili Hatziagelaki, S Schmauss, Richard G. Feltbower, Giancarlo Viberti, P G Steg, S Paulin, S M Marcovina, C. Marzari, Keld Fosgerau, S A Constantin, Adam Kretowski, K Yoshiuchi, K Cypryk, Geloneze, Jason L. Eriksen, Luis Garcia, L A Lavery, A Paroli, C A Ellery, M Morales de Teresa, Martin Ridderstråle, Riccardo C. Bonadonna, Solomon Tesfaye, N Gebeloglu, S Odenbach, A Baumgarten, Frank Schaper, K Dimitriou, F Costantino, O Basat, C A Mathis, V Lassmann-Vague, Kim D-J., J E Pessin, Shi Y-F., Michael Ristow, Kerstin Brismar, V Padilla, M Paganelli, Katinka Stoffels, A Caselli, R Cioni, G Nosso, C Conde, J Foley, M Tsuchiya, I Naumenkova, J M Pou, D Holmes, Richard J MacIsaac, M J Davies, G Jenkins, F Lavalle-Gonzalez, Daphne Owens, E Gibson, Richard E. Gilbert, Foster Avm., Sieradzki J, M W Davis, S Lahiry, James Mason, S Di Silvestre, Ken Walder, B Sporleder, B P Nixon, S Murao, Claus Thamer, V Kren, M A Buyukbese, B Burwinkel, M L Bigelow, C Bellin, P Mayr, J C Beer, Kim K-S., Willy Malaisse, A Ojeda, M Macugowska, A Varró, E Hammer, A R Baker, Alan W. Stitt, Rayaz A. Malik, H A Keizer, A Poscia, V Suri, K Kusterer, Allan D. Struthers, Martin J. Hessner, L A Anderson, Nigel Irwin, J S Christiansen, H V Schaff, D Hancock, L Nielsen, J J Mukherjee, M Essenpreis, C R Stephenson, D Betoulle, T Shibata, L Blonde, S O'Neil, T Hrachovinova, B Mirkiewicz-Sieradzka, G M Valorani, S Jahan, P Luzniak, Stephanie Halford, B Young, E Zabala, P Jousilahti, Hubert Vidal, P Kowey, G Hawthorne, A Zalewski, D Cokkinos, J Maroni, S Drewelow, Y Gao, Maria Paula Macedo, Wendy Dean, Janusz Blasiak, Delporte M-Ll., J Doupis, S Marcu, G Su, D Christakidis, Sabine Sewing, P Pánczél, H Matsumoto, K Rickenbach, A Calì, Giuseppe Derosa, A Linke, H Piperidou, Y Miura, B Kocher, D Nelson, Jo Y-Y., Päivi J. Miettinen, D Leontsini, M Prasek, A R Jones-Leone, H Ahn, R Alemzadeh, Yoshitomo Oka, Anna Solini, Fernanda Ortis, Neville Owen, Simona Cernea, Maciej Pawłowski, Sherry Martin, J L Selam, T Tulokas, K Lammi, Rolland J-F., Stephen Thomas, R.T. de Jongh, C Diehm, S Altimir, E. Manzato, W Szymczak, Michael Khan, S Lally, S Aycheh, I Stengele, Kim S-I., Zbigniew Szybiński, Carol Bower, Koichi Kato, I Evangelista, Eveline Eschwège, S Fujimoto, J Born, Elizabeth J. Mayer-Davis, O Schnell, Y Zhang, C Jørgensen, Lorenzo Piemonti, P Pithova, M Shirai, B. Kilhovd, M Dzabic, A.D. Hughes, Denis Raccah, P Berto, K Nizheradze, Tiinamaija Tuomi, Thomas Nyström, J A Shu, J Ostman, E Cicconetti, Helen E. Thomas, Margareta Svensson, P Vautrin, Andreas Fritsche, Lawrence Rosenberg, K Stoschitzky, M Yamakoshi, B Pandey, Kazuaki Nagashima, N Pound, W Srikusalanukul, D D Sandeman, L Wu, M C Stapperfend, P Saxena, SE Jones, C Colombo, C Caccioppoli, A K Keenan, P Piatkiewicz, H Frobøse, H-Erich Wichmann, J Marquez, C A Maloney, F Stasini, Elena Matteucci, J Arezzo, M Dalfrà, Maria Aisporna, M Nastoll, M Germán, M Riddle, Munehide Matsuhisa, Alessandro Sartorio, Henrik Toft Sørensen, Lars Rydén, I Panagiotou, M Fisher, J P Yeo, M C Riddle, K Anthony, Patrizia Ippolita Patera, T Bobkiewicz-Kozłowska, A Gasiorowska, M Artwohl, Kim K-W., Lutz Heinemann, P V Voss, A Tsuchida, N Ueda, Huriya Beyan, Joachim Rosenbauer, M Sultana, N I Gorbenko, B B Rønn, J Bělobrádková, Michael Haap, J Després, K Cooper, C Tzioras, J Goodwin, J A Myers, Eriksson A-K., M Sahilli, H Sasaki, D Grassetti, S Nencioni, Suzuki J-Y., F Wang, Erica L. Fletcher, H Chen, P Augstein, W J Valentine, Burkhard Göke, Damien Jolley, K Raun, A Seftel, K Okumura, N Follak, A Risse, M Stolinski, Vineet M. Arora, L Vaur, Steven Patterson, T. Heise, Rossi Mce., L. Quarré, D Dorigo, K P Bouter, H Serghides, M. Matsuda, Astrup Av, R Cramb, S Chipchase, Andrzej Lewiński, R Wadwa, C Friedrich, S Giordanetti, Joan Vendrell, Souvik Das, D McGechie, E Locatelli, E Sossidou, D Li, Meinardi, G Thalhammer, Jay S. Skyler, C J Muller, Ulla Feldt-Rasmussen, Susan M. Ring, Richard R. Rubin, S Pramming, Attila Brehm, D Klomp, C Plachot, E Santeusanio, F Roquet, A Naassan, B Pini, Patricia B. Carroll, Maura Pettiti, David S. Rowlands, Jandeleit-Dahm Kam., Timothy M. Frayling, A. K. Sjølie, A. de la Peña, M Franciosi, P A Torjesen, Jonathan C. Levy, S Caruso, B M Sreckovic, S Kim, L Arnaldi, H. B. Holt, M. Parkkonen, Francesco Dotta, M Diamant, H Hilden, A Manginas, N Tsokos, Davis, Barbara Leibiger, M Vaxillaire, V Deschamps, S Hernandez Campos, M Benchimol, Meftun Ahmed, S J Murdoch, Z V Zabarovskaya, Christine Waterman, T Werner, L Brunerova, D Coca-Robinot, D Pejkovic, Jesper Lau, Andreas Melidonis, R A Afonso, V Bronte, W Kotowa, C Broca, Orian S. Shirihai, Stehouwer Cda., Y Nishi, S Wanyonyi, R Fabregate, P A Khanam, S Nepal, Aimin Xu, Jan S. Ulbrecht, S M Ilic, H Hattori, A Panadero Moya, Pietro Castellino, Chiara Guglielmi, Masaru Sakurai, C Barrett, T Trüb, Christine Darwin, S Gross, Carmine Gazzaruso, J Coulaud, L Carbillon, Choi N-H., Anna C. Calkin, U Besenfelder, W Horn, K P Zak, S Nordman, L Zajdenverg, Y Sunaga, G A Spinas, P M Whitty, Kentaro Ohtoshi, Daniela Gasperikova, T Rinaldi, M R Nangle, Vincenzo Positano, C Lasseur, Paul Marsden, M Cinteza, Jeannet Lauenborg, M Párrizas, B Arslan, D Oakley, N S Mason, F Lauster, A B Lowenfels, A H van den Meiracker, M De Smet, P Politakis, Martin Tfj., M Watanabe, Gianna Toffolo, M Kimura, Sudhesh Kumar, A Petrov, G A Raciti, A. M. Umpleby, T Pervin, Maciej T. Małecki, E Tuomilehto-Wolf, Elisabeth R. Mathiesen, R Bonfante, R Gerona, L F Zang, T Sundsten, Mogens Kruhøffer, Johanne Tremblay, Naoto Katakami, L E Foster, Jorge Ferrer, D M Yellon, G Macdonell, T Appl, Levendal R-A., Arany Ejr., B Glisic, R Lestrade, M Dolci, F Pellegrini, K B Rooney, T Ishikawa, H Mayaudon, G Freckmann, V Asnaghi, N Rajkovic, Markus Tiedge, J Marniemi, Jian Peng, D Treacher, P. Z. Zimmet, V Jewhurst, H S Chaudhury, Magnus Møller, E Mathiesen, S Triscornia, Michael Stumvoll, Dirk Wedekind, T Todo, N Schifino, Jacek Kasznicki, C McHorney, Am Sironi, V Patel, N A Abdella, K Ohno, Karin Jandeleit-Dahm, Rafn Benediktsson, K Sztefko, D Yin, Michael R. Christie, J Hill, Simi Ahmed, A Behar, Borys J-M., Don Johns, David G. Armstrong, B Hare, B Szepietowska, S Frojdo, B Meyer, H Hanaire-Broutin, R Reich, A T Ali, A A Dreval, A J Stears, Y Sui, V Mattoo, Wilding Jph., F Azizi, M A Heise, Dana Dabelea, Afshan Siddiq, A. P. Lambert, L Steen, Giuseppe Pugliese, Steen Andersen, F Salman, G Parnaud, Hahn J-U., R A Silvestre, B Idzior-Waluś, B Guy-Grand, Linda D. Voss, Peter G. Jones, E Konoue, G Mello, Vigdis Aas, Yoshifumi Suzuki, Allan Flyvbjerg, L Mogylnytska, J B Hansen, Finn Gustafsson, Jürgen Schrezenmeir, S Kondo, A Ruggiero, I Tarkun, Jan Kopecky, A Umehara, K J Wiefels, D Ogawa, M Austen, F Bataller, John Wahren, Birger Thorsteinsson, G. H. Tomkin, I Pogliaghi, Ahn C-W., M Ishizaki, I Peiró-Martinez, Webb D-L., Ketan Dhatariya, Akihisa Imagawa, Roberto Lupi, P Petit, F Fehse, Jason D. Cooper, Pfeiffer Afh., V Cunsolo, E E Agardh, R Nieuwland, F Ekram, Jensen Rbb., Jens Bülow, HU Häring, Quynh Ntt., D Kawamori, M Herná Alarcó, M Kolpe, Gianfranco Parati, N Labastie, U Mager, D Krenova, M Aragona, Wolffenbuttel Bhr., Pierre Maechler, B P Kovatchev, L Mordhorst, C Coghi, L Wassef, G Füst, Z M Lu, Ewan R. Pearson, D De Cesare, S V McLennan, K Mikoudi, Ali Naji, O Apostolou, A Roussin, J I San Pedro, L N Scherbacheva, A Baroni, McNamara Mrj., M Perez-Maraver, A P Shepelkevich, M Ehren, Alex Harper, C Merezak, M Morrissey, Leena Kinnunen, H Goto, P Maincent, Oluf Pedersen, R. R. Lyu, G Rizzo, V V Bogomolov, N Krasova, G M McGuire, Tina Parkner, A Timi, Johann Bauersachs, S Foussas, S A Schreiber, T Monauni, Schwarz Peh., Allenberg, J D Lee, S Dewan, Y G Zheng, D Carroll, E Sarti, C Wollheim, Anna Kaminski, C Menneila, P Bucher, Xu Jyu., Vincent Rigalleau, A Schöpfer, Hans Jörnvall, A Ben Drief, X Jeunemaitre, E Schuster, Chan Slf., S Bilgic, J Coverly, K Szafraniec, Stalenhoef Afh., H Bergert, David I. W. Phillips, J Maksimovic Pavlovic, Sergio E. Starkstein, E Chaim, T Lehmann-Lintz, P Salacone, Tim Armstrong, Ingrid Klöting, C M Frampton, Franco Cavalot, A.K.Azad Khan, H Rose, Marta Letizia Hribal, Jette Kolding Kristensen, H Gröbe, M Nishi, A Vanderplas, Howlett Hsc., L E Bowen, R Malik, A Wu, Charles C. Richardson, Y Li, P G McNally, Yoon K-H., A Baleydier, M J Murphy, P. M. Nilsson, U Lindblad, Sten Madsbad, T Bíró, Riitta Veijola, Charlotte Glümer, Assunta Pandolfi, Lydia Aguilar-Bryan, M Namba, C Franzen, S Lopatriello, David Russel Jones, S. Cellek, T Derezinski, Ronald P. Stolk, B Yermen, Marina Trento, Christine Feinle-Bisset, T S Futers, Ahn S-K., D Yue, R Nakamura, Shin Tsunekawa, Ortwin Naujok, Marina Vladimirovna Shestakova, Matthew Wintle, M P Guarino, Giovanni Camussi, B Persson, M Brahimi, Raffaella Buzzetti, H Hendrickx, H Schuster, Anthony J. Brookes, N K Hoa, A Ianni Palarchio, T Marte, N H Redemann, M Pufal, Roya Babaei-Jadidi, C Glüimer, Susanne J. Szabo, G Zuodar, Laura Calvillo, M Homering, K Stegner, L Min, Y Haider, S Evangelista, N Soydan, Y Yerushalmy, Z Karimi Anderesi, A Bernjak, Laine A-P., A E Udovichenko, Eva Corpeleijn, A Rieger, Tahseen A Chowdhury, D Schmid, Krystyna Matyka, O V Ivanova, G Ciampittiello, P Vague, I Schmoelzer, Groop P-H., J Weidenhammer, Luis Arnes, A Khoruzhenko, Jelena Skibova, W Jefferson, M Catala, J K Wilson, G Dunseath, A D Tselepis, S. Leotta, A. Sämann, R A Gerber, T Busila, P E Fraser, William J. Jeffcoate, J Pariès, K Huoponen, Anne Jörns, G Shanmugam, A Tsiavou, S Yoshida, Kim M-J., Annapaula Giulietti, S Paillasson, K Tsuchiya, Divyen K Shah, P Saar, S S Juarez, Stefanie Maxion-Bergemann, J Briody, V Schmitz, C M Pena, J Fernádez-Real, S Naruse, M Kalis, A P Klimenko, X H Chen, H.H. Lervang, G Bock, Mirja Tiikkainen, J Potockova, N Pekcanli, George Dragicevic, Timothy M. Rose, David C. Goff, H Komori, V Vasseur-Delannoy, S Hanley, P Hajos, C W Ahn, Matsuoka T-A., J Burns, Petar M. Seferovic, Yuki Kita, K Lyons, K Kohri, Eleftheria Zeggini, Y Ding, G Belcher, Steven V. Edelman, N Dinççaǧ, Christopher J. Rhodes, Manders Rjf., S Giveon, Dario Iafusco, L Li, M C Ribaudo, Kang S-K., Laurie J. Goodyear, L Martinez, C Vermigli, H Dabire, R Raymond, J de Haan, Christopher J. Groves, Å Norberg, H Jahr, M Gloster, Christopher D. Byrne, R Nagase, M Gorska, S Jinagouda, Marcin Baranowski, J M Bruun, L F Fan, Marco Bugliani, Ferdinando Nicoletti, S Born, T Milicic, C Haug, A Imbroinise, Rafael Carmena, G Gedulin, Benoit R. Gauthier, M Ptak, Schweitzer M-A., A Kayserilioǧlu, Rory J. McCrimmon, Ludmila Kazdova, D Pittrow, M Unal, L G Hunsicker, B Komsuoglu, E V Titovich, N L Petrova, M F Saad, T Lindström, D Koev, G Pigas, Pamela Phillips, Timo Otonkoski, S Kanhasura, Ignacio Conget, L Forga, B Rokeya, K Naraine, M Kuroda, F W Hanna, N Hancu, O E Voronko, A Urrutia, E Krusinova, K Stenlof, G. Philippou, W E Brady, Shlomo Sasson, I Cuccuru, S Welte, Md. Shahidul Islam, P Burian, S Creely, B Reinsen, Seema Garg, R Froguel, S Mathi, Myriam Nenquin, R S Crow, L Wogensen, J Brumberg, M Saito, E Hak, C Caravaggi, B Veldman, R E Gregg, A Swaminathan, S Allgauer, F Whitehouse, J Saban-Ruiz, S Rössner, A B Lewandowska, Toshinari Takamura, Elaine M. Dennison, Eugenia Carvalho, Rafael Simó, F Gigli, Chiasson J-L., H Weiss, E Jaeckel, T Krarup Hansen, F Bonnet, J Wu, L A Atramentova, F Murray, Flemming Pociot, A Arne, C. Valadas, F Boomsma, Marketa Sjögren, C Richart, Stefan Schreiber, M M Musri, M Dworacka, E Zakja, Peter Båvenholm, R Gelfand, Steven W. J. Lamberts, Temel Yilmaz, F Péan, K Rave, M Hirata, C Helbig, Y Kido, M Sumarac-Dumanovic, Emma Bingham, N Saadat, L Strindberg, R G Brodows, J Rihl, N C Unwin, Peter Watt, P. Van Rooy, Alexander V. Chibalin, M Michelini, Chantal Mathieu, Samy Hadjadj, W M Sallas, E Schroeder, E Woźniakiewicz, U Golbach, Jeong I-K., M Nam, M Thompson, E Berrone, Leena Ryysy, S Matsuno, G R Fulcher, Jan Schulze, Rachele Berria, Abdol-Reza Esteghamati, Claire Pentecost, D Begic, D Bailbé, J Seo, A Caduff, M Hompesch, E Nishimura, Soroku Yagihashi, Przemysława Jarosz-Chobot, A L Harte, M. E. Trujillo, Dreyfus J-F., G Golor, O Serri, George A. Werther, S Pahler, M Traversa, A. Jotic, I Seljeflot, Renata Krupa, K Irjala, M P Manns, V Sasseville, M R Yun, I Tauveron, Moira Harrison, C Müller-Brandes, Jan Škrha, L Javashvili, C Giusti, Jørgen Rungby, R M Segura, Oh Y-S., P Cavallo Perin, A Piazza, Fumihiko Sakakibara, F Caricato, K Manolopoulos, H. Aladdin, Elena Delgado, C Negut, R Hougaard, H Feldmeier, Francesca Cannata, B Mylari, C Kloos, Xia Li, A Turco, P Thieblot, J Lee, K Koczwara, Gan Huang, I M Briaud, L. Williams, J Ibáñez, Wing-Yee So, Joachim Størling, Kamadjeu Rkk., Sarah J. Bailey, J M González-Posada, M Brändie, M Adiseshiah, N Boschetti, K Tsukiyama, R Iwasa, Naoko Tajima, K K Seah, K Gorbenko, B Saha, Bettina Fischer, M Boronat, Y Kaneko, P K Jaiveer, T Østergård, S Pye, J Rosada, M Fazia, S Duran, Jonas Lindström, Muller Lma., Lee H-C., B Wilke, U Wohlrab, Y López, Philip Hougaard, H B Mortensen, G Riccardi, I Dedov, S Mauri, P G Matthews, D Holt, C Schöfl, N D Hancu, P Tong, Frank Döring, Michael Edmonds, Krystyna Wyka, R Citarrella, M J Mohler, Fabio Vistoli, J Gabaldon, T Gambling, T Barnera, Patrick Gilon, F Hadj Brahim, T M Kuchmerovska, Joachim Spranger, G Collier, Małgorzata Szelachowska, V Hwa, J Herwig, Asish K. Saha, Antje Wienbergen, P Merkouris, V R Driver, G Pellegrini, C Tusek, D Kuhl, J Salvador-Rodríguez, A Rivero, Af Björkesten C-G., L P Aiello, Ángela M. Valverde, A. Sola-Gazagnes, M Lenz, N Duffy, T. Charniauskaya, H Vavrinkova, B B Dokken, N García-Hernandez, M. C. Matteoli, W Neuhuber, B Gutt, Haiyan Wang, C De Tullio, Nikolaos Tentolouris, Susan E. Ozanne, A El-Ouaghlidi, R A Blacken, P K Marsden, S Saragoni, E Fernández, P Thams, Yukio Tanizawa, Cora Weigert, A Bajo-Martinez, A Icks, Yu Liu, Jan Erik Henriksen, J Lupón, C Chrysohoou, C Y Pan, M Enslen, Carsten F. Gotfredsen, S Paxian, C Sert, B Lescrauwaet, Nikolaos Karachalias, Harald Staiger, Soon Dkw., S Mandica, Arild C. Rustan, T Kokko, Luigi Gnudi, L Mantione, Y Mitchel, K Takebayashi, K Lindström, A Akhter, I Calota, Z A Leshchenko, R Henry, E Hagström-Toft, J A Sloniger, C Gredal, Palmer Cna., C Remade, Marion Marchand, S Liew, F Oriente, R Roesen, Ekaterine Bakhtadze, J Bodalski, Věra Lánská, U Baicchi, Terezie Pelikanova, Aniko Varadi, Trudy J. Smith, R Vettermann, Daniel Pipeleers, Becker Rha., S Speier, Saeger H-D., A Tedeschi, Peter J. Grant, W A Scherbaum, R Scardapane, C Arntz, L J Kerr-Bayles, V Poltorack, Sol E-R., G Deniz, Kasper Rossing, Scott J. Jacober, D Lucchesi, Kees J. Gorter, Shin J-S., F Bifari, Ravi Retnakaran, P C Tsiotra, Anna Möllsten, K Mironczuk, A Erdei, Gerry Melino, S G Kauschke, E Stenninger, A Morsanutto, Carmen Fajardo, A. Khan, M S Rasmussen, A Villena, C Ilic, G Gruden, S Uhles, M I Freed, I K Temple, Marco Giorgio, Z Radikova, M Lou, Theodora Temelkova-Kurktschiev, Sorin Ioacara, Patrick A. Ott, Christine Longuet, E Baldassari, Ian Chapman, Cristian Guja, S Seber, K Lundin, Juretschke H-P., A Kanatsuka, Schumicki D-M., Boris Mankovsky, E Liva, Johan Wadén, G Steil, P Chauveau, K Schafer, V Borzì, A S Andersen, D P Mikhailidis, L Groop, Hans J. Arnqvist, M Salvadorini, H. J. Bodansky, Johnny Ludvigsson, A De Paoli, A de Prado, P Olesen, P Syrovatka, V V Klimontov, E Rodriguez, Arthur S. Leon, Alberti Gkm., A Opel, S Kokkoris, S B Hong, Philippe Courtois, L Haque, Maria Sörhede Winzell, M C Beauvois, A Szypowska, D Yu, M Gutniak, D Petzinna, B Isomaa, K S Prickett, Maria Felice Brizzi, Pavel Hamet, P J Hammond, K. F. Michelmore, Yumie Takeshita, N Hariharan, Corrado M. Cilio, G Pogatsa, W G Jerome, E Bartley, K Schlembacher, G Blohmó, Guy A. Rutter, Kyung Mook Choi, S. C Tamer, Felix K. Assah, K A Jandeleit-Dahm, M Chan, H Darius, Jørgen F. P. Wojtaszewski, A Papazisi, M Amaya, A Knopff, M Tadayyon, I J Kim, W Russ, T Myrnäs, M. Tryon, S Poonsatha, Noel Cameron, Kim M-H., Alejandra Tomas, F Homo-Dekarche, G. Di Cianni, M Stotzka, C Solimine, Mikhail Borisovich Antsiferov, H Naserke, M Bianchi-Biscay, J I Lara, Moon C-K., Alain Ktorza, Alison N. Jeffery, V Lilla, Eun Seok Kang, Hanley Ajg., J Widder, R Ratner, C Goretti, P J Weston, J Perkins, V Rasmussen, M Evans, T M Gibson, A Jaffe, S I Chisalita, C Owman, L Hiltunen, E Kakishita, C M Mack, H C Potter, M Femerling, M Desai, M Soinio, K Yang, Patricia L. Brubaker, M Meyer, V Dy, J Berden, R Komers, Milos Adamec, R Petzoldt, Alan G. Robinson, R Stevens, A Doi, A Leunda, Eduard Montanya, Alessandra K Cardozo, N Kraenkel, Claudio Cobelli, U A Mueller, S Yamashiro, B R Gedulin, G Francisco, J Dennenmoser, Lesch K-P., Martin G. Bischof, M Ichita, C Fernandes, Jochen Hampe, S Kern, D Kelly, E Zeender, P Perna, J D Best, A C Calkin, Vivian Fonseca, J Prestle, D G Parkes, Satish K. Garg, T Burrell, B M Fischer, D Kruger, J S Skinner, Lin T-M., Jozef Ukropec, Maria Jeziorska, K Arii, David D. D’Alessio, M B Gomes, L Quandt, I Fragaki, M C Brindisi, A Gladkih, E Kitsou, S Di Cola, T Iwasaki, Peter Diem, T Lakka, V V Popova, G Lee, Hannah J. Welters, K Bonomo, Gavin Kelsey, Y Yerushalmi, A. H. Barnett, H. von Boehmer, K Blomberg, B Haag, M C Preiti, V Sanchez-Margalet, Fowelin Jhr., Y Bernard, M Chalkiadaki, E Grandi, R M Gow, V Schippmann, E. A. M. Gale, R Schiel, R Iwai, O Olari, A Braun, D Koziarska, Bernhard Ludvik, Lee H-W., W P Battisti, N Oliver, M Pankop, H Vertigan, M Pibernik-Okanovic, D Gianneli, J Oh, R Giorgino, M Ballmann, Olle Korsgren, M Pantaleoni, S Zavarella, Göran Sundkvist, Hans Stenlund, Harleah G. Buck, David J. Glass, Morrissey, I Uchimura, M Pugniere, R E Warren, M Mikkola, Baradez M-O., M Weck, C Häuser, D Šrámková, D Voelkel, R Prager, Y L He, M Cornes, O K Vikulova, E Evdemon, Peter R. Cavanagh, Allen Taylor, M Balabolkin, G Schreier, E Stern, J Lips, V Serban, G Sparacino, Roser Casamitjana, Aine McKillop, I Groza, E Bernal, Kathleen M Gillespie, T Ledet, A Garzaniti, F Hawkins, K M Tushaus, C Renaudin, Christina Maier, A Dormi, A Ubertalli, Inge Tetens, M Ostojic, E Pierre-Justin, A Bhushan, E Ur, L I Jeltova, Tilo Moede, E Tibiriça, Zoran Gucev, Knoch K-P., G Pizzolanti, A M Şengül, T P Degenhardt, Cristina Lencioni, M Fitchet, E Santini, E Devangelio, C Panaite, Y I Karachentsev, S B Solerte, Christos Manes, M Lipka, C H Teng, P Mrak, G Fegan, R C Milton, M Negrean, Astrid Plamboeck, L Patti, M Houk, Ritva Kauppinen-Mäkelin, Christoph F Ebenbichler, O Sysoyeva, Frantisek Saudek, H Wysocki, Robert A. Rizza, J Altirriba, Bjørn Richelsen, L. Lam, Rémy Burcelin, A Antsaklis, G Galimberti, R. de Vries, A Lewin, Marcia A. Testa, Lee B-C., M Krauth, A Fonollosa, Marco Cappa, L Rieger, Edoardo Mannucci, André Herchuelz, H Corominola, I Gangat, G Rábago, S Dalla Noce, L Kunselman, J Diehl, M Nattrass, M Kaiser, R Kawamori, E Istoc, Á Pintér, D G Maggs, T Aoki, Csaba Szabó, B Oguzhan, Roberto Ferrari, D M Schumann, Yang Y-W., Hideaki Kaneto, Q Chai, E Blase, Katarzyna Wozniak, D Quijada, George Dailey, U Stier, M Skowronski, Thierry Berney, Adria Giacca, M Askenas, C Tikellis, T Zima, M Lufuma, P T Sawicki, M Dundua, Y Kitahara, M Winter, Janet Lutale, David E. Kelley, Alicia Acitores, Erion, Matthias Möhlig, S Dalal, Birgit Rami, Monster Tbm., Michael Horowitz, L A Leiter, Neil B. Ruderman, David R. Hadden, Mark Walker, I Garai, Michel Polak, A Somogyi, C G Walker, Claes-Göran Östenson, Ou H-C., Thomas Haak, G Kouri, W Pusch, J Fabrin, Robyn J. Tapp, E Zander, B Todorova, Peter Damm, Mine Yilmaz, Michel Pinget, Aila Rissanen, K Leppert, Darren J. Kelly, R B Zaid, A Bohbot, U Fennenkötter, Margot Umpleby, H Rodriguez-Rosas, R. Edwards, J Boavida, S Micheletti, E Bouskela, J Kreuder, N Mizutani, Pardo Icg., R Haberl, S Georgia, D Choi, Monika Lechleitner, R Guerrero, C G Bala, S Y Kim, R Oates, C Miele, E Witthaus, T Sakai, Albert Lecube, Anne Sofie Astrup, Teppo A-M., Margareta Norberg, G Dakovska, I Spanopoulos, P. Djordjevic, Nikolai Petrovsky, J M Fernández-Real, NanWei Tnw., Bilo Hjg., D L Lawlor, E J Henriksen, Anette-Gabriele Ziegler, A McDougall, L Wong, M G Choi, Connie S Karschimkus, M Zaramella, M Gallo, I. G. Lawrence, Viswanathan Mohan, L Valera, H V Silveira, C Pitsavos, Kasper Hermansen, Cloos Pac., K F Hanssen, Samuel W. Cushman, Juergen Eckel, R E Hamman, N Scheffler, C Lengyel, D Bakri, M Fukuda, P Rossetti, A Heerschap, Barbara A. Fielding, Choi Y-H., M Massi-Benedetti, Mykola Khalangot, F. Campi, W A Al Dahi, G Hu, Q Dang, J Ruzickova, A Lifshitz, L M Scheek, A Penfornis, S.C. Campbell, T S Filters, A T Shearer, A Morosanu, M Yngen, K Dezaki, C Damgé, Robert B. Wallace, Neil Portwood, M Henricsson, M Yazawa, J Yantha, G Tepohl, Christopher S. Wendel, Oliveira Jep., R Tracy, M Schindler, M Nabli, H Hosoda, Linda Boselli, B Kunselman, Mentink Cja., L Waselle, P Šamalíková, J Kirchheiner, S Sejil, D Beebe, James D. Otvos, J. J. Holst, J. B. Lopes de Faria, Marian Rewers, Kenneth Cusi, Geng Y-J., F Esfahanian, Francesco Giorgino, D. Freedenberg, R De Caterina, J Seufert, M N Kerstens, W Sturm, M Fujiyama, Konstantinos Makrilakis, A Novials, Lars Berglund, P Strange, W Shim, Clive J. Petry, Michelle M Jack, A E Panteleon, S Wiltshire, G Radulian, C Leperlier, N Téllez, O Sekine, M Karlén, Noël C. Barengo, Qing Qiao, Christian Benedict, C H Saely, M Yoneda, C Gonzalez-Villalpando, Sara Giunti, W Roth, S Wein, E Com, Martin J. Stevens, Giovanni Ghirlanda, Darin Acosta, J Hokanson, M Hauschild, L. A. Powell, Vondra K, Haering H-U., F Afifiyan, K Bendtzen, D M Todd, Marc Y. Donath, Arleta Rewers, Francesco Prisco, R Maeda, A B Kanstrup, M Prats, Y Toledano, Timothy W. Jones, Simon C. Potter, Per Løgstrup Poulsen, M Ligueros-Saylan, Mark L. Evans, Jarl S Torgerson, G Zerbini, L A Ivanova, E Ohmura, C. Kupich, K. Yasuda, J Leprince, A Alaveras, R Ruetter, Kevin C.R. Baynes, Harald Sourij, Y Aramaki, du Prel J-B., Józef Drzewoski, van den Ouweland Jmw., Jochen Seissler, Iain D. Wilkinson, Irina A. Bondar, Y R Yu, S Miclea, S Galatius, T. Havrdova, L Montoya, M Zeller, G C Jones, R B Amazonas, T K Guseva, A Davidescu, Stavros Bousboulas, A. Sandbaek, C Ito, H Taniguchi, M L Simoons, Lars Weinehall, H. Boeing, M A Tambascia, R Grempler, C Speed, A M Mkrtum'yan, A A Darekar, K Hu, Firth Rgr., I Östlund, S Kawazu, P Chitson, B Perry, Joel Dunn, D G Rouiller, K Wagner, Oleg Dyachok, Algis J. Vingrys, S Habu, Mariella Trovati, H Sobajima, Pierre Lecomte, Kim T-H., D Virsaladze, M Oprean, F Pullen, A Rußmann, G J Bruining, Martina Düfer, Wen Xu, Min Y-K., Norman E Cameron, Gianfranco Pagano, K Harley, M Su, J P Le Berre, Sian Ellard, S Howard, D Russell-Jones, Z Li, S Carpenter, E L Thomas, W Tang, Lee M-S., N Ubrich, M. M. McMahon, G Vassilikos, N Brossa, M S Joergensen, S Smith, A Vania, Y Laurent, S Basir, A Freudenthaler, Sally M. Marshall, D Niedermayer, V I Pankiv, J Mentel, S Pruna, J M Pou Torelló, Y Ito, G Chrysos, Werner Kramer, Hironori Yamasaki, L Bowman, F Palumbo, P Ruth, G Lankas, Z H Liao, D Park, W Otter, C Montrone, Sevasti Zervou, Jennifer L. Wilkinson-Berka, Bo Feldt-Rasmussen, I Banu, Paolo Sbraccia, Bani Mukhopadhyay, Mark E. Cooper, M Kidron, Pål R. Njølstad, A M Jonsdottir, M R Burge, G Valpiani, Yutaka Oiso, David J. Hill, T Koch, J Park, A J Plaschke, M P Pye, A Totonelli, S Caronna, B Cremonesi, C Müller, K Tarhzaoui, Valentina Marchetti, M Rodier, Moshe Hod, C N Dang, Trevor A. Howlett, S J Thomas, C Penny, A. de Leiva, Gerald Vervoort, Ghislaine Fontés, Agnieszka Szadkowska, I Al-Zakwani, A Manari, M Eigenthaler, A. Björklund, K Nabe, Mohammad Abdur Rashid, Philips J-C., K Rebrin, Stefan Müller, Claus Thorn Ekstrøm, A A Papageorgiou, L Franco, Paul Hjemdahl, Martine Laville, Flemming S Nielsen, A I Vinik, P Perelli Cippo, Mikael Lehtihet, M Zairis, H Takahashi, M Pietryga, M Kameyama, Jens Knudsen, W W Lautt, Z Rušavý, G Milic, E Pedersen, U Krause, B Balletshofer, J Reviriego, A Scatena, H C Chen, V Gottschall, Alberto Piaggesi, J Gebbie, Maurizio Galderisi, K Nikkiä, A Blayo, D S Fosmark, DL Eizirik, K Busch, Francesco Beguinot, F Capani, A Carrillo, L Nährlich, Thomas Høi-Hansen, Bernard Charbonnel, Edith Schober, Ananda Basu, Deborah J. Smyth, Gerd Plewe, S Vahsen, Claire Levy-Marchal, B S Hansen, V Holtman, S Roche, C Whiteside, A E Fowler, K Helleberg, M Gerl, G Jerums, L Menditto, G Dell'Antonio, A Miles, E Kahan, M Kaibara, V A Serhiyenko, Cees J. Tack, M Shamkhalova, T Linn, R. Koznarova, O Oliyarnyk, Regine Bergholdt, Margaret C. Cam, Matthew Knuiman, U Guiducci, Joanne E. Curran, V Qvisth, F Horkay, Brun J-M., J Jurado, Markku Saraheimo, S Kaltenbach, D D Yin, E Mukai, M Schlosser, Kilbane, K Kølendorf, Hsu Y-J., Steen Gammeltoft, M S Mizel, U Müller, J Bothner, H C Schønheyder, M Ho, I B Bauche, A Etemadi, R F Urdaneta, A Kocijančič, Kim K-R., P E Carey, Olov Rolandsson, S Bochnig, Takahisa Hirose, Baldomero González, Banga J-D., S Vol, R P Hill, F Velazquez, Kathryn Mitchell, S Bott, Z Ma, Richard E Gilbert, D. Mills, A K Gosby, Alison M. Thomas, D Alexander, W Tanaka, Klaus Badenhoop, N D Thuan, B Otto, Gisela Drews, Rui Duarte, S Cantaro, Boulton Ajm., Hélène Hanaire, A Gorski, L Prieto-Sanchez, M Shestakova, Xiaoning Fan, M Higa, J Gurushankar, T Kunitou, D D Trifunovic-Zamaklar, J Nourooz-Zadeh, T F Ørntoft, G Doronzo, P Levéen, B Geloneze, C Fotino, D W Quinn, A Wojciechowska-Luźniak, G Mazzilli, Kook Hwan Kim, M Kaplar, L Dzneladze, Gregory J. Cooney, M Stahlhut, Frances L. Game, E J Bastyr, R Hiles, S. Mariz, T R Pieber, Howlett Hcs., J H Wilmore, Cha B-S., J M Brown, C Laue, Fiona M. Gribble, Susan E. Manley, D L Linemeyer, S G Ashwell, R Sabbah, Hisamitsu Ishihara, N Tronko, M Pohl, H Tindali, Lam Ksl., K Vollmer, I Nagaev, F. Gras, M Corfini, D Lyngsø, A M Sanigorski, Aldo Galluzzo, Alessandro Roberto Dodesini, E Shishko, H Moustgaard, S Piquer, O Tenberken, Ingrid Mühlhauser, A Sturk, Dianne L. Wingate, C Albala, Marie Degerblad, A Kubaszek, Gary W. Cline, J F Markman, J Louw, Y A Redkin, J E Shaw, Gaetano M. De Ferrari, R M Budzinski, I A Snegurakaya, P Kühnen, D Mustapic, Bo Ahrén, C Laflor, Eva Fisher, A Semplicini, C Pandolfo, Myriam Khaldi, K Mattila, Stella Pelengaris, Olga Kordonouri, M Nagao, P I Mansell, K Rduch, R Fahey, R Filipczak, M Suetsugu, J C Vitoria, J Baumert, J Stewart, R S Bonser, Jean Tichet, Christer Andersson, A Şengül, McCuaig, Zorenc Ahg., Xiuqing Guo, H Jordan, K Bieback, Daniela Dietze-Schroeder, J Shin, S Ohga, J Lademann, K C Turner, I V Shutichina, M. Shamkhalova, K Rowley, Rosario Rizzuto, Saraheimo, G. da Silva Xavier, Doss W. Neal, K Akram, H Virtamo, E Dios, K Begum, A Pfuetzner, Tsvetalina Tankova, S Katayama, Christoph Otto, Philip J. Barter, K Zitouni, R Madonna, S Söderberg, S Diaz-Troya, Leszek Czupryniak, S Dietz, P Luźniak, K S Nair, Mark A. Myers, L L Want, S Shaikh, Wolfgang Rathmann, E Wozniakiewicz, L Jönsson, Pernille Poulsen, D F Orr, A B Hauber, F Kelly, Carlo Maria Rotella, J V Costa, Elaine Vieira, E Grodzinsky, Lilianna Majkowska, E Draeger, S Näf, Philip Clarke, S Akter, A Bagust, A Vassibosis, E Lourida, P Chase, G Mardarowicz, Carlo Ricci, A Ugalde-Canitrot, A Wutte, R Streicher, P Ebeling, Taishan Zheng, Marcus Korn, K Summers, Lennarth Nyström, Y Kaburagi, T Furuta, S Freeman, D Skoutas, A A Serhiyenko, K Tryfinopoulou, I. P. Gray, Peter Bjerregaard, R H Elder, M Hosokawa, Marcela Brissova, Kent D. Taylor, R. Da Ros, Carolyn F. Deacon, Andrew D. Morris, N Aydin, Alicia J. Jenkins, L M Serhiyenko, M Sjöstrand, M A Sayeed, A Ardelean, Rolf Holle, I Broom, Giuseppina Imperatore, Massimo Federici, W Sajid, C Bradley, C V Phenekos, W Leonhardt, L Bahia, Veitenhansl, M, Stegner, K, Hierl, F, Dieterle, C, Feldmeier, H, Gutt, B, Landgraf, R, Garrow, A, Vileikyte, L, Findlow, A, Waterman, C, Boulton, A, Shankhdhar, K, Shankhdhar, L, Shankhdhar, U, Petrova, N, Foster, A, Edmonds, M, Ferraresi, R, Caravaggi, C, De Giglio, R, Cavaiani, P, Pogliaghi, I, Sommariva, E, Katz, I, Harlan, A, Miranda palma, B, Prieto sanchez, L, Armstrong, D, Bowker, J, Mizel, M, Cernea, S, Wohlgelernter, J, Kidron, M, Modi, P, Raz, I, Arbit, E, Nosek, L, Kapitza, C, Beckett, P, Gelfand, R, Goldberg, M, Heise, T, Testa, M, Turner, R, Hayes, J, Scranton, R, Simonson, D, Yang, Y, Hsu, Y, Naujok, O, Francini, F, Jörns, A, Tiedge, M, Lenzen, S, Abdel wahab, Y, Marenah, L, Orr, D, Shaw, C, Flatt, P, Chokkalingam, K, Mansell, P, Clausen, P, Ekbom, P, Damm, P, Feldt rasmussen, U, Nielsen, B, Mathiesen, E, Feldt rasmussen, B, Dewan, S, Da Silva, N, Ternan, P, Leong, K, Wilding, J, Asatiani, N, Kurashvili, R, Dundua, M, Shelestova, E, Pagava, K, Ramazashvili, M, Hod, M, Smirnov, S, Petersen, J, Justesen, T, Ringholm Nielsen, L, Müller, C, Højlund, K, Wensaas, A, Kase, E, Aas, V, Rustan, A, Thoresen, G, Levin, K, Beck nielsen, H, Gaster, M, Im, S, Kang, S, Kim, S, Ahn, Y, Lihn, A, Schmoll, D, Werner, T, Kienitz, A, Meyer, M, Barthel, A, Ailett, F, Sutherland, C, Walther, R, Grempler, R, Sasson, S, Reich, R, Tenenbaum, T, Alpert, E, Anfossi, G, Russo, I, Traversa, M, Massucco, P, Mattiello, L, Doronzo, G, Trovati, M, Lally, S, Tan, C, Owens, D, Tomkin, G, Porchay, I, Péan, F, Bellili, N, Betoulle, D, Balkau, B, Tichet, J, Marre, M, Fumeron, F, Chatellier, G, Alhenc gelas, F, Nichols, G, Brown, J, Hayes, R, Bowman, L, Drexel, H, Saely, C, Marte, T, Benzer, W, Langer, P, Hoefle, G, Moll, W, Aczel, S, Karagiannis, E, Lübben, G, Urquhart, R, Edwards, G, Bruce, S, Howlett, H, Cugnardey, N, Turner, K, Park, J, Fiedorek, F, Avogaro, A, Gallo, A, Pinton, P, Rizzuto, R, Murphy, E, Ceolotto, G, Caterson, I, Guy grand, B, Hill, J, Barone, M, Aiello, A, Allochis, G, Borzì, V, Cannatà, F, Caronna, S, D'Avanzo, A, Elli, R, Formoso, G, Paroli, A, Scardapane, R, Sorichetti, P, Tatti, P, Viviani, G, Santeusanio, F, Manzella, D, Grella, R, Abbatecola, A, Paolisso, G, Søndergaard, L, Monster, T, Johnsen, S, Olsen, M, Mclaughlin, J, Sørensen, H, Lervang, H, Rungby, J, Lyssenko, V, Fredriksson, J, Almgren, P, Anevski, D, Orho melander, M, Sjögren, M, Tuomi, T, Groop, L, Jaziri, R, Aubert, R, Tuomilehto, J, Hu, G, Jousilahti, P, Peltonen, M, Lindstrom, J, Laina, A, Alevizaki, M, Philippou, G, Souvatzoglou, A, Anastasiou, E, Alba, S, Metcalf, B, Voss, L, Jeffery, A, Wilkin, T, Glüimer, C, Colagiuri, S, Vistisen, D, Borch johnsen, K, Haynes, A, Bower, C, Bulsara, M, Jones, T, Davis, E, Mortensen, H, Hougaard, P, Holl, R, Swift, P, Pociot, F, Knip, M, Hansen, L, Szadkowska, A, Pietrzak, I, Zmysłowska, A, Wyka, K, Bodalski, J, Swift, R, Hougaard, R, Gerstl, E, Engelsberger, I, Rabl, W, Rosenbauer, J, Gröbe, H, Hofer, S, Krause, U, Dabelea, D, Morgan, T, Pettitt, D, Dolan, L, Mayer davis, E, Pihoker, C, Hillier, T, Imperatore, G, Ruggiero, A, Hamman, R, Stylianou, A, Tentolouris, N, Perrea, D, Tselepis, A, Lourida, E, Kitsou, E, Katsilambros, N, Vedovato, M, Dodesini, A, Lepore, G, Tiengo, A, Trevisan, R, Penno, G, Miccoli, R, Pucci, L, Lucchesi, D, Bandinelli, S, Fotino, C, Triscornia, S, Baldassari, E, Del Prato, S, Reboldi, P, Santeusanio, E, Fuller, J, Langham, R, Gow, R, Zhang, Y, Kelly, D, Christensen, P, Parving, H, Gilbert, R, Chibalin, A, Zhong, Z, Kotova, O, Davidescu, A, Ehrén, I, Ekberg, K, Wahren, J, Wassef, L, Buckley, A, Rooney, K, Briody, J, Thompson, M, Ozanne, S, Thompson, C, Chamson reig, A, Summers, K, Arany, E, Hill, D, Solerte, S, Gazzaruso, C, Locatelli, E, Precerutti, S, Schifino, N, Ferrari, E, Fioravanti, M, Phenekos, C, Ginis, A, Fragaki, I, Chalkiadaki, M, Tzioras, C, Powell, L, Mcguire, G, Jewhurst, V, Trimble, E, Rasmussen, B, Vessby, B, Uusitupa, M, Berglund, L, Pedersen, E, Riccardi, G, Rivellese, A, Tapsell, L, Hermansen, K, Da Silva Xavier, G, Rutter, J, Rutter, G, Briaud, I, Lingohr, M, Dickson, L, Mccuaig, J, Lawrence, J, Rhodes, C, Wikstrom, J, Katzman, S, Shirihai, O, Yang, J, Deng, S, Wang, X, Hessner, M, Wu, J, Wong, R, Sukumvanich, S, Markman, J, Naji, A, Wolf, B, Gao, Z, Rubi, B, Del Arco, A, Satrústegui, J, Maechler, P, Del Guerra, S, Lupi, R, Bugliani, M, Sbrana, S, Torri, S, Boggi, U, Vistoli, F, Mosca, F, Marchetti, P, Rennings, A, Smits, P, Stewart, M, Tack, C, Li, L, Nyström, T, Gutniak, M, Ahrén, B, Holst, J, Sjöholm, Å, Gomes, M, Cailleaux, S, Tibiriça, E, Albertini, J, Chen, H, Mather, R, Valensi, P, Chisalita, S, Arnqvist, H, Kraenkel, N, Adams, V, Linke, A, Gielen, S, Schuler, G, Humbrecht, R, Cipollone, F, Iezzi, A, Fazia, M, Pini, B, Cucurullo, C, De Cesare, D, Schmidt, A, Mazurek, T, Zang, L, Mannion, J, Diehl, J, Martin, J, Martella, A, Zalewski, A, Shi, Y, Otter, W, Winter, M, Doering, W, Standi, E, Schnell, O, Kragelund, C, Køber, L, Faber, J, Hildebrandt, P, Steffensen, R, Pankowska, E, Szypowska, A, Lipka, M, Herwig, J, Scholl schilling, G, Böhles, H, Robertson, K, Schönle, E, Gucev, Z, Mordhorst, L, Tamer, S, Gall, M, Ludvigsson, J, Hoogma, R, Hammond, P, Gomis, R, Kerr, D, Bruttomesso, D, Bouter, P, Wiefels, K, De La Calle, H, Schweitzer, D, Pfohl, M, Torlone, E, Krinelke, L, Conget, I, Storms, F, Rodriguez, J, Leperlier, C, Davies, M, Peter, R, Luzio, S, Dunseath, G, Miles, A, Hare, B, Backx, K, Pauvaday, V, Caselli, A, Marfia, G, Battista, C, Veves, A, Spallone, V, Uccioli, L, Gonzalez, J, Peyrot, M, Rubin, R, Leventhal, H, Scheffler, N, Ulbrecht, J, Cavanagh, P, Perrin, N, Oglesby, A, Bastyr, E, Ziegler, D, Siekierka kleiser, E, Meyer, B, Schweers, M, Selvarajah, D, Wilkinson, I, Emery, C, Shaw, P, Griffiths, P, Tesfaye, S, Obrosova, I, Arezzo, J, Phillips, K, Gribble, F, Williams, L, Reimann, F, Iakoubov, R, Whiteside, C, Brubaker, P, Acitores, A, González, N, Sancho, V, Valverde, I, Villanueva peñacarrillo, M, Martín duce, A, Trigo, M, Arnés, L, Burkart, V, Ichino, N, Ohashi, A, Klein, B, Paxian, S, Schmid, R, Karlsen, A, Heding, P, Frobøse, H, Rønn, S, Kruhøffer, M, Ørntoft, T, Nerup, J, Mandrup poulsen, T, Billestrup, N, Cardozo, A, Ortis, F, Feng, Y, Rasschaert, J, Van Eylen, F, Storling, J, Herchuelz, A, Eizirik, D, Wang, H, Kouri, G, Wollheim, C, Ribaux, P, Hammar, E, Parnaud, G, Rouiller, D, Bosco, D, Halban, P, Midthjell, K, Carlsson, S, Grill, V, Lau, C, Færch, K, Glümer, C, Tetens, I, Jørgensen, T, Tillin, T, Forouhi, N, Mckeigue, P, Chaturvedi, N, Zethelius, B, Hales, C, Berne, C, Coleman, R, Stevens, R, Holman, R, Christensen, J, Sandbæk, A, Lauritzen, T, Irwin, N, Gault, V, Green, B, Harriott, P, O'Harte, F, Bouman, S, Ursø, B, Brand, C, Rolin, B, Ribel, U, Schäffer, L, Maggs, D, Ceriello, A, Frias, J, Wang, Y, Ruggles, J, Kolterman, O, Piconi, L, Weyer, C, Want, L, Ratner, R, Uwaifo, G, Thornberry, N, Eiermann, G, Kim, D, Lankas, G, Leiting, B, Li, Z, Lyons, K, Petrov, A, Sinha Roy, R, Woods, A, Woods, J, Zhang, B, Fisher, M, Moller, D, Weber, A, Dreyer, M, Bellin, C, Schmitz, V, Roesen, R, Nescheret, A, Bose, A, Mocanu, M, Carr, R, Yellon, D, Manolopoulos, K, Born, S, Wagner, A, Jeziorska, M, Ben Drief, A, Bashir, M, Tomlinson, D, Malik, R, Zeymer, U, Schwarzmaier d'assie, A, Petzinna, D, Chiasson, J, Stratton, I, Af Björkesten, C, Fagerudd, J, Rosengård bärlund, M, Forsblom, C, Pettersson fernholm, K, Waden, J, Saraheimo, M, Rönnback, M, Thorn, L, Groop, P, Mollsten, A, Svensson, M, Kockum, I, Rudberg, S, Brismar, K, Dahlquist, G, Hovind, P, Hansen, T, Tarnow, L, Thiel, S, Jensen, B, Flyvbjerg, A, Kankova, K, Hertlova, M, Krusova, D, Schwenke, S, Ott, J, Thom, S, Mistry, P, Sjolie, A, Larsen, B, Witt, N, Hughes, A, Samira, H, Lahiry, S, Howlader, S, Parveen, S, Azad Khan, A, Clarke, P, Gray, A, Phillips, L, Phillips, P, Chittleborough, C, Baldock, K, Taylor, A, Davis, W, Davis, T, Knuiman, M, Hendrie, D, Worthley, D, Nicolucci, A, Pellegrini, F, De Berardis, G, Franciosi, M, Belfiglio, M, Rossi, M, Sacco, M, Valentini, M, Richardson, C, Jones, P, Persaud, S, Hussain, K, Clark, A, Christie, M, Gniuli, D, Hribal, M, Accili, D, Khan, M, Zervou, S, Cheung, L, Abouna, S, Ifandi, V, Pelengaris, S, Luco, R, Ferrer, J, Ma, D, Shield, J, Dean, W, Leclerc, I, Knauf, C, Burcelin, R, Kelsey, G, Powers, A, Shostak, A, Ferrara, N, Poffenberger, G, Jerome, W, Brissova, M, Geloneze, S, Tambascia, M, Pareja, J, Chaim, E, Silveira, H, Geloneze, B, Ravikumar, B, Carey, P, Snaar, J, Dheelchand, D, Cook, D, Neely, D, Taylor, G, Morris, P, Taylor, R, Stears, A, Masding, M, Wootton, S, Sandeman, D, Klimes, I, Wein, S, Gasperikova, D, Ukropec, J, Wiernsperger, N, Sebokova, E, Manco, M, Mingrone, G, Granato, L, Greco, A, Nanni, G, Castagneto, M, Vidal, H, Calvani, M, Ferrannini, E, Alvarsson, M, Sundkvist, G, Lager, I, Henricsson, M, Berntorp, K, Fernqvist forbes, E, Steen, L, Örn, T, Shutler, S, Bianchi biscay, M, Rosenstock, J, Sugimoto, D, Strange, P, Stewart, J, Soltes Rak, E, Dailey, G, Kloos, C, Müller, U, Sämann, A, Femerling, M, Risse, A, Jecht, M, Haak, T, Garg, R, Lawrence, I, Akinsola, M, Mcnally, P, Garber, A, Kim, H, Draeger, E, Aydın, L, Şengül, A, Kürklü, A, Uçak, S, Basat, O, Seber, S, Altuntaş, Y, Jin, J, Yu, Y, Yu, H, Zhang, X, Mattoo, V, Eckland, D, Widel, M, Duran, S, Fajardo, C, Strand, J, Knight, D, Oakley, D, Tan, M, Sato, A, Nagao, M, Aki, N, Nakagami, T, Iwamoto, Y, Zhou, Z, Li, X, Huang, G, Yan, X, Yang, L, Peng, J, Wang, J, Tan, S, Tang, W, Fürnsinn, C, Brunmair, B, Wagner, L, Gras, F, Artwohl, M, Zierhut, B, Waldhäusl, W, Shine, B, Hopkins, D, Anand, V, Lim, E, Raval, U, Sharp, P, Corder, R, Lipkin, D, Lahiri, A, Bartnik, M, Rydén, L, Ferrari, R, Malmberg, K, Pyörälä, K, Simoons, M, Standl, E, Soler soler, J, Öhrvik, J, Bruce, D, Starkstein, S, Schauer, U, Astrup, A, Pietraszek, L, Nielsen, F, Rossing, P, Ali, S, Smidt, U, Yokoyama, H, Pavkov, M, Knowler, W, Bennett, P, Nelson, R, López alba, A, Morcillo, L, Caballero, A, Montoya, L, Jiménez, A, Maceira, B, Lewis, J, Ravid, M, Wajman, A, Tadgell, C, Remuzzi, G, Hunsicker, L, Wadén, J, Wessman, M, Taskinen, M, Pugliese, G, Amadio, L, Menini, S, Oddi, G, Ricci, C, Iacobini, C, Pricci, F, Sorcini, M, Pesce, C, Migliaccio, E, Giorgio, M, Pelicci, P, Di Mario, U, Lassila, M, Jandeleit dahm, K, Seah, K, Calkin, A, Allen, T, Cooper, M, Lopes De Faria, J, Cavakcanti, T, Silva, K, Ferrari, A, Cellek, S, Foxwell, N, Cotter, M, Cameron, N, Tennagels, N, Jordan, H, Stahl, P, Voss, M, Welte, S, Werner, U, Lehmann, R, Moeschel, K, Baumgartner, F, Oeckinghaus, A, Beck, A, Weigert, C, Hennige, A, Schleicher, E, Häring, H, Müssig, K, Staiger, H, Natalicchio, A, Laviola, L, De Tullio, C, Renna, L, Giorgino, R, Giorgino, F, Falasca, M, Maffucci, T, Park, D, Song, J, Lee, D, Lee, Y, Hariharan, N, Kunselman, L, Gu, L, Sasseville, V, Harrity, T, Cheng, P, Pratley, R, Schweizer, A, Mills, D, Ahren, B, Kim, T, Song, X, Van Poelje, P, Potter, S, Dang, Q, Fujitaki, J, Linemeyer, D, Landau, B, Erion, M, Pankop, M, Golay, A, Després, J, Sjöström, L, Lawlor, D, Legg, K, Ur, E, Houweling, S, Kleefstra, N, Meyboom de Jong, B, Bilo, H, Schlömer, G, Meyer, G, Kasper, J, Mühlhauser, I, Young, B, Taylor, J, Friede, T, Hollis, S, Mason, J, Long, A, Gambling, T, Pauline, L, Burns, E, New, J, Gibson, M, Betteridge, D, Leiter, L, Whitty, P, Eccles, M, Hawthorne, G, Grimshaw, J, Steen, I, Vanoli, A, Wood, L, Speed, C, Mcdowell, D, Rewers, M, Maahs, D, Wadwa, R, Eckel, R, Tracy, R, Pfützner, A, Strotmann, H, Schulze, J, Hohberg, C, Pahler, S, Forst, T, Ambery, P, Sydall, H, Cooper, C, Dennison, E, Sayer, A, Barker, D, Phillips, D, Lalic, N, Ostojic, M, Lalic, K, Zamaklar, M, Jotic, A, Ilic, M, Rajkovic, N, Lukic, L, Milicic, T, Vergès, B, Zeller, M, Steg, P, Beer, J, Brisard, C, Brindisi, M, Dentan, G, Laurent, Y, Janin manificat, L, Makki, H, Ravisy, J, Cottin, Y, Ajjan, R, Grant, P, Futers, T, Carter, A, Rasmussen, M, Bruun, J, Pedersen, S, Richelsen, B, Dietze schroeder, D, Sell, H, Koenen, M, Eckel, J, Delporte, M, Bauche, I, Brichard, S, Ait El Mkadem, S, Rezsohazy, R, Tsiotra, P, Tsigos, C, Gatsiou, C, Raptis, S, Walker, C, Bryson, J, Hancock, D, Takahashi, N, Hatakeyama, H, Kasai, H, Gauthier, B, Iezzi, M, Fukuda, M, Duhamel, D, Ravier, M, Düfer, M, Neye, Y, Krippeit drews, P, Sausbier, U, Arntz, C, Sausbier, M, Neuhuber, W, Ruth, P, Drews, G, Beauvois, M, Rolland, J, Jonas, J, Merezak, C, Henquin, J, Gilon, P, Jabin Gustafsson, A, Dzabic, M, Islam, M, Vaxillaire, M, Cheyssac, C, Dina, C, Vasseur delannoy, V, Leprêtre, F, Siddiq, A, Froguel, P, Neve, B, Fernandez zapico, M, Ashkenazi katalan, V, Urrutia, R, Melloul, D, Froguel, R, Poulsen, P, Wojtaszewski, J, Richter, E, Vaag, A, Granhall, C, Renström, E, Luthman, H, Isomaa, B, Gloyn, A, Edghill, E, Pearson, E, Mackay, D, Temple, I, Noyes, K, Freedenberg, D, Gillespie, K, Lambert, A, Gale, E, Ellard, S, Hattersley, A, Fanelli, C, Porcellati, F, Rossetti, P, Busciantella, N, Billi, C, Burrin, D, Bolli, G, Bingham, E, Dunn, J, Sutcliffe goulden, J, Marsden, P, Amiel, S, Davis, R, Kennedy martin, T, Peters, J, Wittrup jensen, K, Mcewan, P, Morrissey, M, Currie, C, Akram, K, Pedersen bjergaard, U, Thorsteinsson, B, Pibernik okanovic, M, Peros, K, Begic, D, Szabo, S, Metelko, Z, Vlaiculescu, M, Calota, I, Busila, T, Bruckner, I, Giannakopoulou, D, Lindner, H, Hrachovinova, T, Fejfarova, V, Csémy, L, Malcomson, J, Campbell, M, Pandolfi, A, Giardinelli, A, Di Tomo, P, Di Silvestre, S, Di Fulvio, P, Capani, F, Consoli, A, Roesen, P, Patruno, A, Grilli, A, Capani, R, Felaco, M, Boner, G, Mccarroll, K, Brenner, B, De Zeeuw, D, Kowey, P, Shahinfar, S, Crow, R, Iso, K, Kuboki, K, Tada, H, Yoshino, G, Schjoedt, K, Andersen, S, Distiller, L, Degenhardt, T, Szabo, J, Khalifah, R, Schotzinger, R, Achenbach, P, Knopff, A, Naserke, H, Ziegler, A, Bonifacio, E, Valera, L, Jardin, B, Roche, S, Lampasona, V, Pugniere, M, Roquet, F, Granier, C, Laune, D, Afifiyan, F, Cheung, R, Yantha, J, Jackowski, G, Dosch, H, Nakanishi, K, Kogawa, N, Komatsu, Y, Fontés, G, Imamura, T, Ilic, C, Puech, C, Ktorza, A, Bataille, D, Dalle, S, Fosgerau, K, Gelling, R, Nishimura, E, Andersen, B, Madsen, P, Lau, J, Streicher, R, Wagner, K, Vettermann, R, Potterat, O, Renard, E, Panteleon, A, Kolopp, M, Rebrin, K, Steil, G, Hariri, F, Darwin, C, Saad, M, Buckingham, B, Kunselman, B, Wong, L, Istoc, E, Leach, J, Purvis, R, Monfre, S, Fischer, J, Garg, S, Ahmann, A, Ruchti, T, Gandhi, G, Nuttall, G, Mullany, C, Schaff, H, Williams, B, Rizza, R, Mcmahon, M, Gates, G, Mentel, J, Smith, R, Crook, J, Hosszúfalusi, N, Vatay, Á, Palik, È, Füst, G, Karádi, I, Romics, L, Pánczél, P, Aurich, K, Voelker, U, Braun, A, Nguyen, L, Kriketos, A, Denver, G, Üceyler, N, Schütt, M, Lesch, K, Mössner, R, Sommer, C, Seda, O, Liska, F, Kazdova, L, Sedova, L, Krenova, D, Zima, T, Tremblay, J, Kren, V, Hamet, P, Klöting, N, Follak, N, Klöting, I, Dessapt, C, Dei Cas, A, Baradez, M, Hayward, A, Thomas, S, Viberti, G, Gnudi, L, Gale, C, Thallas, V, Thomas, M, Candido, R, Burns, W, Forbes, J, Shymanskyy, I, Kuchmerovska, T, Klimenko, A, Jaeckel, E, Manns, M, Von Boehmer, H, Hedrich, H, Téllez, N, Montolio, M, Estimes, E, Rodríguez mulero, S, Soler, J, Montanya, E, Liu, Y, Chen, J, Rowlands, D, Chan, H, Simeonov, I, Anthony, K, Zelaya, F, Williams, S, Brammer, M, Mountjoy, P, Bailey, S, Shaw, J, Sicree, R, Dunstan, D, Cameron, A, Zimmet, P, Hewitt, S, Graff iversen, S, Assah, F, Fezeu, L, Kengne, A, Awah, P, Mbanya, J, Shu, J, Kamadjeu, R, Kiawi, E, Kerényi, Z, Péterfalvi, A, Bosnyák, Z, Madarász, E, Tabák, Á, Szánthó, J, Rákóczi, I, Tamás, G, Di Bartolo, P, Valpiani, G, Di Martino, M, Scaramuzza, A, Saragoni, S, Degli Esposti, E, Cannatá, F, Gudbjornsdottir, S, Cederholm, J, Nilsson, P, Eliasson, B, Miettinen, M, Miettinen, J, Nan, H, Dong, Y, Gao, W, Sun, B, Wang, N, Fu, F, Shi, H, Ding, M, Lorenzo, C, Serrano ríos, M, Martínez larrad, M, González sánchez, J, Seclén, S, Villena, A, Gonzalez villalpando, C, Williams, K, Stern, M, Haffner, S, Sakurai, M, Miura, K, Kita, Y, Takamura, T, Ota, T, Ishizaki, M, Morikawa, Y, Nakagawa, H, Szybiński, Z, Szurkowska, M, Mardarowicz, G, Łopatyński, J, Gilis januszewska, A, Szafraniec, K, Nicer, T, Kwon, H, Lee, J, Lee, H, Park, Y, Choi, Y, Jang, S, Song, B, Yoon, K, Lee, W, Cha, B, Lee, K, Son, H, Jørgensen, M, Moustgaard, H, Bjerregaard, P, Ebara, F, Salmon, J, Owen, N, Welborn, T, Armstrong, T, Jolley, D, Galtier, F, Deschamps, V, Borys, J, Lasfargues, G, Andre, P, Born, C, Royer, B, Wilpart, E, Cailleau, M, Eschwege, E, Timar, R, Serban, V, Vlad, A, Diaconu, L, Rosu, M, Olari, O, Sima, A, Qiao, Q, Chappuis, B, Diem, P, Christ, E, Iafusco, D, Prisco, F, Gemma, C, Mattera, S, Sanges, M, Menneila, C, Sommese, L, Jarosz chobot, P, Polanska, J, Feltbower, R, Mckinney, P, Stephenson, C, Bodansky, H, Icks, A, Du Prel, J, Grabert, M, Giani, G, Kyvik, K, Skytthe, A, Ioacara, S, Farcasiu, E, Bradescu, O, Guja, C, Scutaru, G, Savu, O, Ionescu tirgoviste, C, Ola, T, Hawa, M, Buzzetti, R, Scherbaum, W, Kolb, H, Thivolet, C, Hunter, S, Hadden, D, Guntram, S, De Leiva, A, Mauricio, D, Pozzilli, P, Leslie, R, Benediktsson, R, Jonsdottir, A, Einarsdottir, A, Reynisdottir, I, Aspelund, T, Grant, S, Thorleifsson, G, Sigurdsson, G, Stefansson, K, Gudnason, V, Wollitzer, A, Jovanovic, L, Lobo, P, Martí, M, Preiti, M, Urdaneta, R, Juarez, S, Schober, E, Thon, A, Rami, B, Tringham, J, Buyukbese, M, Sakamoto, Y, Inoue, Y, Matsumoto, H, Oono, K, Tokumasa, Y, Gorter, K, Janssen, P, Stolk, R, Van Hessen, P, Rutten, G, Palik, É, Niedermayer, D, Murro, A, Coghi, C, Federici, M, Benedetti, M, Koehler, C, Henkel, E, Temelkova kurktschiev, T, Stier, U, Ott, P, Siegert, G, Bergmann, S, Hanefeld, M, Leonhardt, W, Sayeed, M, Mahtab, H, Khanam, P, Banu, A, Rashid, M, Mulnier, H, Seaman, H, Lovell, D, Soedamah mathu, S, Colhoun, H, Lawrenson, R, Diehm, C, Lange, S, Darius, H, Pittrow, D, Haberl, R, Von Stritzky, B, Tepohl, G, Allenberg, J, Trampisch, H, Soinio, M, Marniemi, J, Laakso, M, Lehto, S, Rönnemaa, T, Ito, C, Sasaki, H, Ishida, S, Maeda, R, Barengo, N, Lakka, T, Köhler, C, Benke, I, Raccah, D, Bailleau, C, Vexiau, P, Vaur, L, Aydin, N, Topsever, P, Filiz, T, Dayan, A, Bulgurlu, S, Gebeloglu, N, Demirtunc, R, Dagar, A, Skliros, E, Sotiropoulos, A, Vassibosis, A, Xipnitos, C, Liva, E, Chronopoulos, I, Merkouris, P, Skourtis, S, Pappas, S, Charbonnel, B, Baigts, F, Dumenil, V, Paillasson, S, Baleydier, A, Hanaire, H, Sert, C, Chabrier, G, Rodier, M, Fontaine, P, Kim, J, Miyake, Y, Sakai, T, Takamatsu, K, Tomioka, Y, Sugano, H, Murao, S, Shimizu, I, Unwin, N, Nag, S, Roglic, G, Connolly, V, Roper, N, Goodwin, J, Kelly, W, Thomsen, R, Hundborg, H, Schønheyder, H, Khalangot, M, Gang, H, Tajima, N, Bianchi, C, Giovannitti, M, Pellegrini, G, Caricato, F, Bertolotto, A, Corfini, M, Guzder, R, Gatling, W, Byrne, C, Varillas, V, Boronat, M, Carrillo, A, La Roche, F, Ojeda, A, López, Y, Marrero, D, Nóvoa, J, Shahidul Alam Khan, A, Thaware, P, Gangat, I, Howlett, T, Jenum, A, Holme, I, Birkeland, K, Sourij, H, Stoschitzky, K, Klein, W, Roth, M, Dittrich, P, Wascher, T, Hilding, A, Eriksson, A, Agardh, E, Efendic, S, Östenson, C, Levitt, N, Bradshaw, D, Salzsieder, E, Freyse, E, Rutscher, A, Heinke, P, Augstein, P, Makino, H, Kainou, Y, Konoue, E, Ohno, K, Ebisui, O, Fujii, Y, Kondo, S, Fujiyama, M, Tanaka, K, Takemoto, K, Kida, K, Onuma, Y, Osawa, H, Tuomilehto wolf, E, Kinnunen, L, Laine, A, Kokko, T, Kakko, T, Hermann, R, Veijola, R, Simell, O, Ilonen, J, Guglielmi, C, Galgani, A, Beretta Anguissola, G, D'Avola, D, Bakhtadze, E, Weiss, H, Wedekind, D, Bilbao, J, San Pedro, J, Vitoria, J, Martul, P, Castaño, L, Badenhoop, K, Ramos Lopez, E, Usadel, K, Wägner, A, Cloos, P, Stahlhut, M, Bergholdt, R, Ramos, E, Taxvig, C, Vella, A, Smyth, D, Cooper, J, Undlien, D, Rønningen, K, Ionescu tîrgovişte, C, Savage, D, Dunger, D, Strachan, D, Ring, S, Todd, J, Mironczuk, K, Kretowski, A, Kinalska, I, Nutland, S, Guja, L, Nielsen, L, Gammeltoft, S, Schwarz, P, Towers, W, Fischer, S, Mcrae, J, Willis, J, Scott, R, Potter, H, Merriman, T, Frampton, C, George, P, Spranger, J, Möhlig, M, Hoffmann, K, Müller, S, Osterhoff, M, Ristow, M, Boeing, H, Pfeiffer, A, Li, Y, Fisher, E, Burwinkel, B, Schrezenmeir, J, Mager, U, Pulkkinen, L, Lindi, V, Lindström, J, Xiu, L, Sui, Y, Weng, J, Kalis, M, Cilio, C, Olde, B, Owman, C, Levéen, P, Da Ros, R, Assaloni, R, Maier, A, Quagliaro, L, Zuodar, G, Zakja, E, Gu, H, Nordman, S, Brookes, A, Prince, J, Helwig, U, Rubin, D, Hampe, J, Schreiber, S, Fölsch, U, Döring, F, Porzio, O, Massa, O, Cunsolo, V, Njolstad, P, Terrinoni, A, Melino, G, Colombo, C, Federici, G, Barbetti, F, Herder, C, Bongardt, F, Schöpfer, A, Rathmann, W, Martin, S, Holle, R, Thorand, B, Wichmann, H, Koenig, W, Illig, T, Blasiak, J, Arabski, M, Krupa, R, Wozniak, K, Dabrowski, J, Kasznicki, J, Zurawska, M, Drzewoski, J, Kose, H, Matsumoto, K, Wilke, B, Kerr bayles, L, Walder, K, Civitarese, A, Jowett, J, Curran, J, Elliott, K, Trevaskis, J, Bishara, N, Wanyonyi, S, Sanigorski, A, Blangero, J, Kissebah, A, Collier, G, Carlsson, E, Arner, P, Ridderstråle, M, Nitz, I, Lindner, I, Suzuki, S, Hinokio, Y, Hirai, M, Yamada, T, Yoshizumi, S, Tanizawa, Y, Matsutani, A, Ishihara, H, Takahashi, K, Katagiri, H, Oka, Y, Nam, M, Hong, S, Ahn, C, Kim, Y, Zeggini, E, Parkinson, J, Groves, C, Frayling, T, Hitman, G, Walker, M, Sampson, M, Levy, J, Weedon, M, Wiltshire, S, Owen, K, Halford, S, Mccarthy, M, Shehadeh, N, Bakri, D, Gershoni baruch, R, Yasuda, K, Okada, T, Sunaga, Y, Kajimoto, Y, Shibasaki, T, Kaburagi, Y, Kadowaki, T, Estalella, I, Rica, I, Vazquez, J, De Andrade, P, Van Den Ouweland, J, Maassen, J, Huoponen, K, Savontaus, M, Dimitrijevic Sreckovic, V, Djordjevic, P, Popovic, S, Gostiljac, D, Canovic, F, Sreckovic, B, Colak, E, Obrenovic, R, Milic, G, Glisic, B, Etemadi, A, Saadat, N, Azizi, F, Tsur, A, Cohen, Y, Yerushalmi, Y, Wainstein, J, Norberg, M, Eriksson, J, Lindahl, B, Andersson, C, Rolandsson, O, Stenlund, H, Weinehall, L, Lecomte, P, Vol, S, Cacès, E, Chabrolle, C, Halimi, J, Nijpels, G, Dekker, J, Bouter, L, Heine, R, Löbner, K, Mollenhauer, U, Baumgarten, A, Com, E, Sargin, M, Karadeniz, S, Sengul, A, Suleymanoglu, Y, Pekcanli, N, Yilmaz, T, Cicero, A, Dormi, A, Miconi, A, D'Addato, S, Laghi, L, Brillante, R, Bernardi, R, Grandi, E, Gaddi, A, Jones, M, Lacey, L, Bergenheim, K, Yamagata, F, Yamakoshi, M, Takahashi, M, Kawazu, S, Festa, A, Hanley, A, Otvos, J, Goff, D, Wajngot, A, Cerasi, E, Baumert, J, Schneider, A, Löwel, H, Roussel, R, Müller brandes, C, Ballmann, M, Nährlich, L, Thalhammer, G, Nastoll, M, Schwarz, J, Johne, U, Erfurth, M, Lüddeke, H, Liebl, A, Kotowa, W, Maclaine, G, Evers, T, Pontiroli, A, Pizzocri, P, Paganelli, M, Folli, F, Jung, D, Park, M, Henriksen, J, Durck, T, Weghuber, D, Roden, M, Tura, A, Pacini, G, Bischof, M, Widhalm, K, Sharp, G, Shanmugam, G, Straub, S, Michael, D, Chow, R, Regazzi, R, Gerona, R, Martin, T, Waselle, L, Tomas, A, Min, L, Pessin, J, Björklund, A, Ma, Z, Portwood, N, Parton, L, Smith, E, Diraison, F, Tsuboi, T, Lehtihet, M, Webb, D, Honkanen, R, Knoch, K, Meisterfeld, R, Bergert, H, Kolpe, M, Altkrüger, A, Saeger, H, Solimena, M, Haspel, D, Aguilar bryan, L, Bryan, J, Ullrich, S, Berchtold, S, Ranta, F, Seebohm, G, Alexander, D, Wulff, P, Kuhl, D, Lang, F, Speier, S, Yang, S, Rose, T, Rupnik, M, Varadi, A, Mitchell, K, Schwappach, B, Bleck, C, Wienbergen, A, Rustenbeck, I, Vieira, E, Gylfe, E, Seissler, J, Wohlrab, U, Schmiegelt, D, Ruetter, R, Herten, M, Lechner, A, Nolan, A, Blacken, R, Habener, J, Gao, R, Ustinov, J, Korsgren, O, Mikkola, M, Lundin, K, Otonkoski, T, Jahr, H, Bieback, K, Kern, S, Brendel, C, Brendel, M, Bretzel, R, Taniguchi, S, Ohgawara, H, Tsuchiya, K, Tsuchiya, M, Okochi, H, Kelter, A, Dohrmann, C, Austen, M, Aicher, B, Maedler, K, Schumann, D, Iwakura, Y, Donath, M, Peter, A, Opel, A, Seufert, J, Fernández, E, Serradas, P, Martín, M, Plachot, C, Bailbé, D, Gangnerau, M, Gavete, M, Fajardo, S, Escrivá, F, Portha, B, Álvarez, C, Lipsett, M, Jamal, A, Hanley, S, Castellarin, M, Rosenberg, L, Bhushan, A, Georgia, S, Calderari, S, Meile, M, Miettinen, P, Palgi, J, Virkamäki, A, Ferris, W, Campbell, S, Armstrong, L, Hole, N, Lako, M, Macfarlane, W, Barbera, A, Altirriba, J, Nadal, B, Larsen, M, Gotfredsen, C, Reusens, B, Sparre, T, Kalbe, L, Leunda, A, Kruhoffer, M, Orntoft, T, Remade, C, Dasilva Xavier, G, Motakis, E, Nason, G, Leibiger, B, Berggren, P, Leibiger, I, Uhles, S, Moede, T, Welters, H, Senkel, S, Erdmann, S, Thomas, H, Morgan, N, Irminger, J, Rickenbach, K, Jackson, D, Chan, S, Dezaki, K, Watanabe, M, Hosoda, H, Kangawa, K, Yada, T, Kühnen, P, Laubner, K, Hernández, R, Silvestre, R, Egido, E, Châtenet, D, Leprince, J, Chartrel, N, Vaudry, H, Marco, J, Zhang, F, Zhang, Q, Tengholm, A, Thore, S, Costes, S, Longuet, C, Broca, C, Baltrusch, S, Dyachok, O, Thams, P, Anwar, M, Capito, K, Radu, R, Fujimoto, S, Mukai, E, Shimono, D, Nabe, K, Shimodahira, M, Kominato, R, Aramaki, Y, Yamada, Y, Seino, Y, Giroix, M, Agascioglu, E, Courtois, P, Malaisse, W, Sener, A, Piquer, S, Barcelo batllori, S, Julia, M, Li, J, Lou, M, Zhang, J, Zhou, Q, Zhao, G, Webb, G, Dalal, S, Garcia, C, Saxena, P, Houk, M, Nenquin, M, Abdel ghany, M, Miele, C, Romano, C, Corbo, V, Maitan, M, Andreozzi, F, Ungaro, P, Oriente, F, Raciti, G, Formisano, P, Beguinot, F, Mcclenaghan, N, Mccluskey, J, Patterson, S, Efanov, A, Sewing, S, Bokvist, K, Gromada, J, Frederiksen, A, Juhl, C, Schwarts, M, Schmitz, O, Andersen, P, Valeri, C, Castelli, M, Bonfante, R, Beyan, H, Elouil, H, Khaldi, M, Evangelista, S, Zeender, E, Berney, T, Franklin, I, Sergeev, P, Chervonsky, A, Nyblom, H, Ahmed, M, Bergsten, P, Sol, E, Kharroubi, I, Ladriere, L, Cnop, M, Moffitt, J, Fielding, B, Currie, J, Staiger, K, Brandhorst, D, Winter, D, Kellerer, M, Oprescu, A, Naassan, A, Klimentova, T, Constantin, S, Tang, C, Uchino, H, Lam, L, Wheeler, M, Fantus, G, Giacca, A, Ortsäter, H, Sundsten, T, Youshikawa, H, Winzell, M, Montrone, C, Martemucci, S, Perrini, S, Caccioppoli, C, Størling, J, Grassetti, D, Scipioni, A, Dotta, F, Yamamoto, N, Tsunekawa, S, Ito, Y, Oiso, Y, Miura, Y, Niki, I, Scrocchi, L, Ha, K, Wang, F, Chen, Y, Wu, L, Fraser, P, Yermen, B, Lilla, V, Kaminski, A, Mathe, Z, Dupraz, P, Zbinden, M, Filo, A, Bucher, P, Rinsch, C, Thorens, B, Pepper, M, Estilles, E, Sigrist, S, Rieger, L, Mandes, K, Bohbot, A, Pinget, M, Kessler, L, Parab, P, Katdare, M, Galande, S, Saha, B, Yoshida, A, Satoh, J, Homo dekarche, F, Coulaud, J, Durant, S, Drexhage, H, Mabley, J, Deb, A, Wallace, R, Pacher, P, Elder, R, Szabo, C, Schlosser, M, Mentel, R, Moya suri, V, Wassmuth, R, Gürtler, L, Ankelo, M, Westerlund, A, Blomberg, K, Hinkkanen, A, Popova, V, Gruzov, M, Afanasyeva, V, Kulikovskaya, A, Melnichenko, S, Mankovsky, B, Zak, K, Koczwara, K, Warncke, K, Kawasaki, E, Imagawa, A, Uchigata, Y, Kobayashi, M, Abiru, N, Yamasaki, H, Eguchi, K, Chrul, S, Polakowska, E, Heinrich, A, Walter, M, Pitocco, D, Visalli, N, Crinò, A, Costantino, F, Manfrini, S, Spera, S, Suraci, C, Patera, P, Matteoli, M, Schiaffini, R, Ghirlanda, G, Leotta, S, Hatziagelaki, E, Tsiavou, A, Degiannis, D, Chaidaroglou, A, Manginas, A, Koniavitou, K, Desai, M, Williams, A, Horton, V, Bingley, P, Cull, C, Citarrella, R, Richiusa, P, Mattina, A, Criscimanna, A, Mantione, L, Bronte, V, Pizzolanti, G, Galluzzo, A, Giordano, C, Giulietti, A, Stoffels, K, Overbergh, L, Mathieu, C, Bilgic, S, Aktas, E, Salman, F, Yillar, G, Yilmaz, M, Deniz, G, Valorani, G, Pozzilli, R, Weets, I, Truyen, I, Verschraegen, I, Van Der Auwera, B, De Schepper, J, Dorchy, H, Lebrethon, M, Van Gaal, L, Van Rooy, P, Pipeleers, D, Gorus, F, Shtandel, S, Atramentova, L, Karachentsev, Y, Kravchun, N, Koval, S, Poltorak, V, Levchenko, T, Snegurakaya, I, Miloslavskiy, D, Bojko, V, Resnik, L, Chico, A, Rojas, I, Julià, M, Novials, A, Bendlová, B, Včelák, J, Vaňková, M, Šrámková, D, Šamalíková, P, Kvasničková, H, Vondra, K, Petrone, A, Vania, A, Zavarella, S, Alemanno, I, Di Cola, S, Ribaudo, M, Leonetti, F, Angel, B, Carrasco, E, Santos, J, Albala, C, Oyarzún, A, Pérez bravo, F, Petry, C, Ong, K, Michelmore, K, Artigas, S, Wingate, D, De Zegher, F, Ibáñez, L, Prestle, J, Adomeit, A, Hammer, E, Zieher, T, Missler, B, Appl, T, Schindler, M, Brodbeck, K, Machicao, F, Just, M, Færgeman, N, Knudsen, J, Quint, M, Tschank, G, Korn, M, Henriksen, E, Dokken, B, Sloniger, J, Dörig, J, Quarré, L, Piatkiewicz, P, Taton, J, Czech, A, Gorski, A, Jebens, E, Brennesvik, E, Ktori, C, Ruzzin, J, Shepherd, P, Jensen, J, Lakka, H, Rankinen, T, Leon, A, Skinner, J, Wilmore, J, Rao, D, Bouchard, C, Vendrell, J, Chacon, M, Garcia españa, A, Fernandez real, J, Gutierrez, C, Richart, C, Takeshita, Y, Shimizu, A, Hamaguchi, E, Kaneko, S, Hřebíček, J, Orel, M, Lichnovská, R, Gwozdziewiczová, S, Chlup, R, Faturos, I, Tournis, S, Fotinakis, P, Thomakos, P, Manousaki, M, Leontsini, D, Taxildaris, K, Mitrakou, A, Hur, K, Shim, W, Cho, Y, Lim, S, Kim, K, Beregszaszi, M, Chevenne, D, Sebag, G, De Kerdanet, M, Huet, F, Polak, M, Lacombe, D, De Paoli, A, Levy marchal, C, Mokhort, T, Shishko, E, Shepelkevich, A, Benito, M, Arribas, M, Valverde, A, Menghini, R, Marchetti, V, Cardellini, M, Sbraccia, P, Lauro, D, Lauro, R, Ali, A, Penny, C, Van Der Merwe, M, Paiker, J, Psaras, G, Ekram, F, Crowther, N, Musri, M, Corominola, H, Casamitjana, R, Párrizas, M, Renström, F, Burén, J, Park, C, Lee, G, Kang, E, Sanchez margalet, V, Gonzalez yanes, C, Diaz troya, S, Rodriguez De Fonseca, F, Mcnamara, M, Boschetti, N, Schmid, D, Spinas, G, Trüb, T, Niessen, M, Kuhlmann, J, Neumann haefelin, C, Belz, U, Juretschke, H, Kramer, W, Herling, A, Markova, I, Oliyarnyk, O, Cahova, M, Manders, R, Koopman, R, Zorenc, A, Keizer, H, Van Loon, L, Straczkowski, M, Kowalska, I, Dzienis straczkowska, S, Nikolajuk, A, Gorska, M, Zabielski, P, Baranowski, M, Gorski, J, De Haan, J, Klomp, D, Heerschap, A, Corpeleijn, E, Budzinski, R, Stengele, I, Schuler, M, Selzle, N, Lehmann lintz, T, Heckel, A, Vavrinkova, H, Meskhishvili, E, Furier, S, Parkes, H, Cooney, G, Alemzadeh, R, Tushaus, K, Nencioni, S, Giovannitti, G, Longo, V, De Vries, R, Kerstens, M, Van Tol, A, Dullaart, R, Mcbride, R, Denke, M, Pearson, T, Battisti, W, Brady, W, Palmisano, J, Tuzova, O, Wahl, H, Hong, Q, Luz, K, Xu, G, Schmülling, R, Liebich, H, Oomen, P, Hattori, H, Smit, A, Scheek, L, Thomaseth, K, Lajoix, A, Gauthey, A, Dietz, S, Jahannault, C, Manteghetti, M, Petit, P, Gross, R, Ostenson, C, Quynh, N, Florén, A, Langel, U, Gedulin, B, Smith, P, Prickett, K, Tryon, M, Barnhill, S, Yeoh, T, Young, A, Hiles, R, Carpenter, T, Serota, D, Schafer, K, Ross, P, Nelson, D, Rebelatto, M, Ikeda, H, Nagashima, K, Tsukiyama, K, Todo, T, Trombetta, M, Boselli, L, Calì, A, Cretti, A, Monauni, T, Bifari, F, Bonora, E, Muggeo, M, Bonadonna, R, Gredal, C, Rosenfalck, A, Dejgaard, A, Hilsted, J, Vankova, M, Sramkova, D, Samalikova, P, Vcelak, J, Kvasnickova, H, Bendlova, B, Rudovich, N, Rochlitz, H, Ritzel, R, Butler, A, Butler, P, Murphy, M, Körner, A, Csillag, J, Pintér, Á, Toman, M, Gray, I, Vielwerth, S, Rinnov, A, Jensen, R, Juul, A, Uitterlinden, P, Bruining, G, Lamberts, S, Rasmussen, E, Malis, C, Ekstrom, C, Arne, A, James, J, Thomas, P, Cavan, D, Owona, A, Ozaki, R, So, W, Tong, P, Chan, M, Wong, G, Cockram, C, Chan, J, Redemann, N, Götz, B, Lahm, P, Mader, G, Tadayyon, M, Oh, Y, Schippmann, V, Kluge, R, Bornstein, S, Joost, H, Bae, H, Lee, B, Vertigan, H, Carroll, D, Griffiths, L, Coghlan, M, Freeman, S, Toffolo, G, Dalla Man, C, Basu, R, Cobelli, C, Bertoldo, A, Price, J, Mathis, C, Mason, N, Holt, D, Kelley, C, Mckolanis, T, Kelley, D, Whyte, M, Jackson, N, Beale, R, Treacher, D, Carroll, P, Jones, R, Umpleby, M, Jaquet, D, Boiko, J, Rigal, O, Czernichow, P, Lévy marchal, C, Qvisth, V, Hagström toft, E, Moberg, E, Bolinder, J, Sjöstrand, M, Gudbjörnsdottir, S, Strindberg, L, Lönnroth, P, Mick, D, Sumarac dumanovic, M, Cvijovic, G, Kendereski, A, Pejkovic, D, Zoric, S, Casanueva, F, Dieguez, C, Singh, R, Basu, A, Chittilapilly, E, Johnson, M, Abdallah, B, Shubeska Stratrova, S, Svendsen, O, Dhatariya, K, Bigelow, M, Nair, K, Lundgren, M, Rüge, T, Myrnäs, T, Gimeno, R, Suri, V, Li, D, Huard, C, Martinez, R, Vettore, M, Sironi, A, Gastaldelli, A, Mari, A, Ciociaro, D, Buzzigoli, E, Pettiti, M, Positano, V, Lombardi, M, Radziuk, J, Pye, S, Brehm, A, Krssak, M, Bernroider, E, Anderwald, C, Nowotny, P, Cline, G, Shulman, G, Kotsa, K, Papazisi, A, Spanopoulos, I, Giovos, I, Suzuki, A, Sobajima, H, Naruse, S, Kitagawa, M, Ishiguro, H, Futakuchi, S, Goto, H, Hines, G, Kennedy, I, Matthews, D, Radikova, Z, Koska, J, Ksinantova, L, Imrich, R, Huckova, M, Vigas, M, Wallace, T, Rajala, U, Hiltunen, L, Keinänen kiukaanniemi, S, Noh, J, Choi, N, Chung, J, Min, Y, Lee, M, Holt, H, Wood, P, Darekar, A, Gross, S, Matthies, K, Weck, M, Malinska, H, Beifort, R, Berria, R, Defronzo, R, Cusi, K, Gorshunska, M, Karachenzev, Y, López bermejo, A, Pratt, K, Hwa, V, Recasens, M, Broch, M, Rosenfeld, R, Fernández real, J, Ricart, W, Grunnet, L, Pedersen, B, Franke, B, Fleming, S, Lemke, N, Laue, C, Pfeuffer, M, Lecube, A, Hernández, C, Genescà, J, García, L, Francisco, G, Simó, R, Kraml, P, Syrovatka, P, Brunerova, L, Smejkalova, V, Potockova, J, Andel, M, Leshchenko, Z, Poltorack, V, Krasova, N, Gladkih, A, Yang, K, Chamson, A, Thyssen, S, Rojo Llobet, A, Christoffersen, B, Raun, K, Fledelius, C, Vinterby, A, Golozoubova, V, Afonso, R, Ribeiro, R, Macedo, M, Guarino, M, Yang, G, Kurita, S, Misu, H, Akahori, H, Cerf, M, Nkomo, X, Muller, C, Du Toit, D, Louw, J, Wolfe coote, S, Nikishin, P, Zagayko, A, Taylor, K, Guo, X, Langefeld, C, Cur, J, Jinagouda, S, Bowden, D, Hokanson, J, Rotter, J, Liew, C, Wise, S, Yeo, K, Teng, C, Fisher, F, Trujillo, M, Hanif, W, Mcternan, P, Barnett, A, Scherer, P, Kumar, S, Kaltenbach, S, Stumvoll, M, Mlynarski, W, Zmyslowska, A, Andrzejewski, W, Shojaee moradie, F, Das, S, Stolinski, M, Jefferson, W, Cramb, R, Shahmanesh, M, Lyngsø, D, Simonsen, L, Bülow, J, Meinardi, J, Sluiter, W, Wolffenbuttel, B, Bonnet, F, Guebre egziabher, F, Rabasa, R, Laville, M, Gosby, A, Maloney, C, Haering, H, Patarrao, R, Lautt, W, Correia, N, Santos, A, Leite, V, Boavida, J, Nanwei, T, Bobbioni harsch, E, Lehmann, T, Sztajzel, J, Morel, P, Huber, O, Chassot, G, Assimacopoulos jeannet, F, Gedulin, G, Baron, A, Hendrickx, H, Lane, J, Coverly, J, Simcox, J, Stocks, J, Brown, L, Beha, A, Juretschke, P, Gerl, M, Klebach, M, Biemer daub, G, Pérez del pulgar, S, Zorzano, A, Heinsbroek, A, D'Alessio, D, Van Dijk, G, Tornero, M, Bailey, C, Mack, C, Wilson, J, Parkes, D, Kusunoki, M, Sakakibara, F, Kato, K, Okabayashi, N, Nakamura, T, Miyata, T, Habu, S, Nakamura, R, Nakasone, Y, Yasaka, T, Ishihara, R, Morikawa, R, Otake, K, Nakaya, Y, Ruzickova, J, Rossmeisl, M, Flachs, P, Sponarova, J, Prazak, T, Matejkova, O, Kopecky, J, Gram, D, Liu, W, Bödvarsdóttir, T, Hansen, J, Sturis, J, Kern, W, Hallschmid, M, Benedict, C, Schultes, B, Born, J, Fehm, H, Westerbacka, J, Lammi, K, Häkkinen, A, Rissanen, A, Yki järvinen, H, Mayr, P, Mertl roetzer, M, Lauster, F, Pohl, M, Lerch, M, Haslbeck, M, Eriksen, J, Rahlfs, V, Serhiyenko, V, Serhiyenko, A, Serhiyenko, L, Radulian, G, Vladica, M, Panaite, C, Balas, B, Derosa, G, Dumas, A, Fiorito, A, Prieto, P, Cancelas, J, Loba, J, Czupryniak, L, Bialasiewicz, P, Pawlowski, M, Nowak, D, Dupuy, O, Le Berre, J, Bordier, L, Rousseau, C, Mayaudon, H, Bauduceau, B, Bossi, A, Meregalli, G, Balini, A, Berzi, D, Cremonesi, B, Cerrato, D, Rezzani, C, Tumiati, M, Han, K, Min, K, Kim, E, Ahn, K, Ahn, H, Argüelles, I, Forga, L, Izquierdo, M, Gorostiaga, E, Fuentes, C, Ibáñez, J, Rivero, A, Baynes, K, Pentecost, C, Bell, J, Thomas, E, Umpleby, A, Kuhl, J, Ruderman, N, Musi, N, Goodyear, L, Patti, M, Thorell, A, Nygren, J, Ljungkvist, O, Degerblad, M, Ståhle, A, Brismar, T, Saha, A, Båvenholm, P, Aydemir, D, Kiran, B, Unal, M, Okumus, N, Kayserilioglu, A, Perkins, J, Kıran, B, Ünal, M, Salman, S, Yıllar, G, Özer, E, Kayserilioǧlu, A, Yılmaz, T, Dinççaǧ, N, Tikkanen, H, Macdonald, A, Harrison, M, Dickinson, H, Bone, A, Watt, P, Østergård, T, Short, K, Saltin, B, Di Mauro, M, Papalia, G, Battiato, R, Giuffrida, D, Boemi, G, Castellino, P, Akter, S, Akhter, A, Pervin, T, Ahmed, S, Ahmed, K, Saleh, F, Chaudhury, H, Tankova, T, Dakovska, G, Lazarova, M, Dakovska, L, Kirilov, G, Koev, D, Torgerson, J, Hauptman, J, Boldrin, M, Pan, C, Gao, Y, Lindgärde, F, Broom, I, Takeda, H, Oana, F, Matsuzawa, A, Hashizume, H, Akahane, S, Cornes, M, Lund, S, Poulsen, G, Frandsen, M, Pedersen, O, Pankiv, V, Yngen, M, Hjemdahl, P, Wallén, N, Florow, D, Leyck Dieken, M, Kitahara, Y, Mine, T, Konya, H, Hamaguchi, T, Satani, K, Umehara, A, Ishikawa, T, Kohri, K, Hasegawa, Y, Suehiro, A, Kakishita, E, Namba, M, Liao, Z, Yao, B, Belcher, G, Mariz, S, Moules, I, Butzer, R, Langenfeld, M, Köder, C, Majali, K, Adiseshiah, M, Betteridge, J, Pratipanawatr, T, Chotmongkol, R, Kanhasura, S, Pratipanawatr, W, Miyazaki, Y, Matsuda, M, Nagasawa, T, Kuroda, J, Dey, D, Chovatia, M, Nag, A, Pandey, B, Nag, B, Thomas, L, Krauth, M, Allgauer, S, Besenfelder, U, Dennenmoser, J, Moon, C, Chae, S, Kim, M, Jo, Y, Shin, J, Ahn, S, Lee, S, Panadero Moya, A, Rodriguez, E, Gonzalo, A, Sánchez vilar, O, Lara, J, Rovira, A, Otto, C, Otto, B, Göke, B, Parhofer, K, Juurinen, L, Tiikkainen, M, Graner, M, Bajaj, M, Suraamornkul, S, Ucak, S, Kurklu, A, Argon, D, Canbek, E, Altuntas, Y, Schöfl, C, Franzen, C, Gregg, R, Swaminathan, A, Frost, C, Nepal, S, Raymond, R, Mosqueda garcia, R, Johns, D, Gilmore, K, Perriello, G, Pampanelli, S, Di Pietro, C, Rinaldi, T, Brunetti, P, Oshinyemi, K, Garcia, S, Curtis, P, Zambanini, A, Home, P, Pocock, S, Dargie, H, Komajda, M, Jones, N, Münscher, C, Potthoff, F, Golbach, U, Weidenhammer, J, Kusterer, K, Lundershausen, R, O'Neill, M, Goldstein, B, Wooddell, M, Strow, L, Waterhouse, B, Cobitz, A, Wyne, K, Porter, L, Weston, W, Chen, T, James, R, Kravitz, B, Pinkowski, D, Ruxer, J, Mozdzan, M, Siejka, A, Kaiser, M, Häuser, C, Jacober, S, Zagar, A, Althouse, S, Pinaire, J, Becker, R, Frick, A, Rave, K, Moses, R, Ways, K, Krones, R, Basir, S, Klein, C, Sawicki, P, Rotella, C, Pala, L, Dicembrini, I, Mannucci, E, Annuzzi, G, De Natale, C, Bozzetto, L, Patti, L, Cipriano, P, Campaigne, B, Malone, J, Bai, S, Reviriego, J, Augendre ferrante, B, Schneider, K, Schweitzer, M, Fach, E, Busch, K, Karimi Anderesi, Z, Haupt, A, Eckert, H, Peiker, J, Fritsche, A, Janka, H, Plewe, G, Kliebe frisch, C, Maxeiner, S, Teng, L, Chan, C, Ernest, C, Skrivanek, Z, Brodows, R, Soon, D, Chung, K, Rußmann, A, Ryysy, L, Hänninen, J, Hulme, S, Kauppinen mäkelin, R, Lahdenperä, S, Lehtonen, R, Levanen, H, Nikkiä, K, Tulokas, T, Virtamo, H, Vahatalo, M, Fulcher, G, Lavalle gonzalez, F, De La Pena, A, Lim, M, Scholtz, H, Derezinski, T, Gerber, R, Hauber, A, Bolinder, B, Johnson, F, Boehm, B, Keiding, J, Raastam, J, Møller, M, Parkner, T, Jørgensen, C, Smedegaard, J, Christiansen, J, Mcdougall, A, Fitch, M, Nelson, G, Mueller, U, Saemann, A, Ishii, H, Iburi, T, Furuya, M, Yamagami, K, Sekine, O, Yamashiro, S, Ishibashi, R, Tsujii, S, Sauriol, L, Lescrauwaet, B, Heckmann, B, Helbig, C, Franke, I, Schiel, R, Oguzhan, B, Gursoy, N, Gutiérrez, E, García, P, Rokeya, B, Hossain, M, Ali, L, Ivanova, O, Gorbenko, N, Gladkich, A, Gorbenko, K, Blase, E, Nguyen, T, Su, G, Gao, H, Carr, E, Wintle, M, Fineman, M, Calara, F, Han, J, Aisporna, M, Zabala, E, Fehse, F, Trautmann, M, Halseth, A, Nauck, M, Kendall, D, Riddle, M, Zhuang, D, Buse, J, Henry, R, Linnebjerg, H, Kothare, P, De La Peña, A, Atkins, M, Bjerre Knudsen, L, Voss, P, Hompesch, M, Filipczak, R, Le, T, Zdravkovic, M, Gumprecht, J, Deacon, C, Plamboeck, A, Guivarch, P, Dreyfus, J, Mathi, S, Castaigne, J, Drucker, D, Kruger, D, Burrell, T, Gloster, M, Crean, J, Herrmann, K, Kovatchev, B, Cox, D, Mccall, A, Whitehouse, F, Chapman, I, Parker, B, Doran, S, Feinle bisset, C, Wishart, J, Lush, C, Mcintyre, S, Deckhut, D, Horowitz, M, El ouaghlidi, A, Rehring, E, Holmes, D, Sallas, W, He, Y, Watson, C, Ligueros saylan, M, Foley, J, Narayanan, S, Thomas, A, Shah, D, Gopalan, B, Vakkalanka, S, Arch, J, Ryskjær, J, Krarup, T, Madsbad, S, Vilsbøll, T, Ciani, S, Bardini, G, Pezzatini, A, Cappadona, A, Joergensen, M, Jensen holm, H, Kristensen, L, Kanstrup, A, Mckillop, A, Duffy, N, Lindsay, J, Bell, P, Hansen, B, Gronemann, S, Wilken, M, Herman, G, Zhao, P, Dietrich, B, Golor, G, Schrodter, A, Keymeulen, B, Lasseter, K, Kipnes, M, Hilliard, D, Tanen, M, De Smet, M, Van Dyck, K, Tanaka, W, Gottesdiener, K, Wagner, J, Hoffmann, T, S, V, Demuth, H, Paule, S, Myers, M, Nikolovski, B, Fujiwara, H, Hosokawa, M, Fukuda, K, Nishi, Y, Fujita, Y, Yamada, K, Ueda, N, Jones leone, A, Yu, T, Barilla, D, Ho, Y, Makrilakis, K, Panagiotakos, D, Dimosthenopoulos, C, Ioannidis, I, Chrysohoou, C, Pitsavos, C, Kuo, S, Levendal, R, Poonsatha, S, Jones, G, Fahey, R, Hoa, N, Norberg, Å, Liepinsh, E, Phan, D, Thuan, N, Jörnvall, H, Sillard, R, Tessari, P, Kiwanuka, E, Cristini, M, Zaramella, M, Enslen, M, Garcia rodenas, C, Yazawa, M, Imai, Y, Ohmura, E, Tsuchida, A, Matsuda, A, Hosaka, D, Horie, H, Ichita, M, Hisano, Y, Woodhead, S, Xu, W, Chen, X, Cavalot, F, Bonomo, K, Perna, P, Bacillo, E, Salacone, P, Gallo, M, Gaia, E, Vinik, A, Yu, D, Heise, M, Freed, M, Aguilera, E, Pellitero, S, Näf, S, Bendtzen, K, Nicoletti, F, Hahn, J, Bochnig, S, Koenig, H, Sporleder, B, Maisonneuve, P, Lowenfels, A, Kerner, W, Lankisch, P, Thai, A, Mohan, V, Khalid, B, Yeo, J, Gasiorowska, A, Talar wojnarowska, R, Malecka panas, E, Schindler, K, Rieger, A, Gmeinhart, B, Schlembacher, K, Merz, P, Ludvik, B, Müller, N, Rodriguez, F, Aas, A, Seljeflot, I, Huang, C, Biswas, N, Hashimoto, N, Kamatani, Y, Suzuki, Y, Yagui, K, Saito, Y, Iwai, R, Takahashi, H, Yoshida, S, Skowronski, M, Zozulinska, D, Juszczyk, J, Wierusz wysocka, B, Peterkova, V, Kuraeva, T, Scherbacheva, L, Andrianova, E, Maximova, V, Titovich, E, Danne, T, Bittner, C, Hanaire broutin, H, Schumicki, D, Souhami, E, Morrison, G, Purewal, T, Weston, P, Šmahelová, A, Rušavý, Z, Kožnarová, R, Loyková, V, Bělobrádková, J, Devries, J, Retnakaran, R, Hochman, J, Melki, V, Zinman, B, Corbi, S, Costanza, F, Fioriti, E, Cappa, M, Jaroň, M, Martínek, V, Piechatzek, R, Klaff, L, Prager, R, Robinson, A, Penfornis, A, Thomas, R, Selam, J, Sola gazagnes, A, Vitacolonna, E, Canonico, V, Fabietti, P, Iorio, M, Orsini Federici, M, Timi, A, Massi Benedetti, M, Sarti, E, Ashwell, S, Gebbie, J, Siebenhofer, A, Plank, J, Berghold, A, Horvath, K, Mrak, P, Jeitler, K, Pieber, T, Heller, S, Gottlieb, P, Paul, J, Chase, P, Menditto, L, Antuña, R, Grimaldi, A, Brun, J, Vialettes, B, Halimi, S, Dubroca, I, Blayo, A, Gómez peralta, F, Santos mazo, E, Payeras más, F, Abreu padín, C, Santos palacios, S, Salvador rodríguez, J, Burge, M, Schroeder, E, Witthaus, E, Johnston, P, Bradley, C, Kudva, Y, Jenkins, G, Pons, G, Quandt, L, Gebel, J, Vogelsang, D, Smith, S, Isley, W, Russell jones, D, Maier, C, Mustapic, D, Schuster, E, Luger, A, Eher, R, Koznarova, R, Rubesova, I, Pelikanova, T, Skibova, J, Sanz, F, Ampudia blasco, F, Gabaldon, J, Catala, M, Carmena, R, Heinemann, L, Kronshage, B, Ward, K, Sass, D, Essenpreis, M, Voelkel, D, Lodwig, V, Nguyen, M, Mondok, A, Friedrich, C, Caduff, A, Totonelli, A, Longhitano, S, Agrò, F, Edelman, S, Morrison, Z, Velazquez, F, Howard, S, Banks, R, Berger, B, Burian, P, Nilsson, K, Karlén, M, Rylander, E, Blonde, L, Freemantle, N, Ross, S, Duhot, D, Eggertsen, R, Hobbs, F, Martinez, L, Stridde, E, Skyler, J, Tusek, C, Stephan, J, Krasner, A, Landschulz, W, Sha, S, Bott, S, Bergenstal, R, Damgé, C, Ubrich, N, Kaltenbacher, M, Maincent, P, Wutte, A, Bock, G, Balent, B, Midtgaard, A, Rønn, B, Edgerton, D, Cherrington, A, Neal, D, Scott, M, Glass, D, Bowen, L, Wilson, W, Hobbs, C, Leach, C, Sivakumaran, S, Strack, T, De Meyts, P, Aladdin, H, Palsgaard, J, Theede, A, Sajid, W, Hinrichsen, J, Klaproth, B, Lademann, J, Østergaard, J, Andersen, A, Boss, A, Cheatham, W, Pfuetzner, A, Larbig, M, Forst, S, Abdollahnia, R, Grenningloh, M, Leatherdale, B, Bartley, E, Schwartz, S, Buchea, O, Hoss, U, Shah, R, Endo, T, Hata, S, Yamazaki, H, Hernandez Campos, S, Busciantella Ricci, N, Kaufman, F, Halvorson, M, Carpenter, S, Cooper, K, Mueller, J, Van Wasen, H, Brumberg, J, Rduch, K, Mertens, S, Reeß, F, Renz, H, Maran, A, Sparacino, G, Pavanini, A, Corazza, S, Crepaldi, M, Poscia, A, Acosta, D, Salcedo, D, Delgado, E, Novoa, J, Hawkins, F, Parramón, M, Mesa, J, Parhimovich, R, Darko, D, Odusanya, P, Pullen, F, Mukherjee, S, Child, D, Redkin, Y, Dreval, A, Bogomolov, V, Östgren, C, Grodzinsky, E, Lindström, K, Borgquist, L, Fegan, G, Hamliton, P, Mccrimmon, R, Evans, M, Fan, X, Ding, Y, Sherwin, R, Boomsma, F, Pramming, S, Fischer, B, Soydan, N, Eckhard, M, Saar, P, Kreuder, J, Linn, T, Holstein, A, Plaschke, A, Ptak, M, Egberts, E, El din, J, Kirchheiner, J, Hoashi, S, Khamis, A, Kilbane, M, Cannon, D, Gribben, A, Firth, R, Kinsley, B, Cranston, I, De Galan, B, De Mol, P, Wennekes, L, Due andersen, R, Lundkvist, J, Jönsson, L, Mukhopadhyay, B, Deans, K, Kesson, C, Jendrike, N, Buck, H, Abicht, A, Haug, C, Freckmann, G, Warren, R, Sommerfield, A, Allen, K, Deary, I, Frier, B, Høi hansen, T, Wu, A, Holtman, V, Tenberken, O, Maurer, H, Al zakwani, I, Bullano, M, Baron, J, Willey, V, Nattrass, M, Kurtzhals, P, Colding jorgensen, M, Massi benedetti, M, Murray, F, Lin, Z, Kølendorf, K, Prasek, M, Philotheou, A, Javashvili, L, Virsaladze, D, Kajaia, N, Raposo, J, Pratas, S, Fernandes, C, Valadas, C, Duarte, R, Gardete correia, L, Locatelli, M, Patera, I, Bottazzo, G, Hadjidakis, D, Mylonakis, A, Raptis, A, Papaefstathiou, A, Hedman, C, Frystyk, J, Fridell, K, Jönsson, A, Lindström, T, Saito, M, Eto, M, Kaku, K, Stotzka, M, Stein, G, Prince, M, Kulzer, B, Scholze, A, Hermanns, N, Kubiak, T, Starostina, E, Shavrikova, E, Furuhashi, N, Hirose, T, Kuroda, M, Kimura, M, Ishizawa, M, Sarui, H, Takeda, N, Furuta, T, Drewelow, S, Lindloh, C, Paddison, C, Faimalie, M, Flett, R, Micheletti, S, Perelli Cippo, P, Mantovani, L, Su, M, Trento, M, Bajardi, M, Passera, P, Miselli, V, Tomalino, M, Borgo, E, Cavallo, F, Porta, M, Miclea, S, Bogatean, M, Hancu, N, Leppert, K, Muller, U, Rittmeier, H, Mchorney, C, Myers, J, Reinecker, H, Meier, J, Gallwitz, B, Askenas, M, Vollmer, K, Schmidt, W, Kyrou, I, Souvatzoglou, E, Cseh, K, Baranyi, E, Kaszas, E, Szocs, A, Melczer, Z, Sikter, M, Szenthe, P, Palik, E, Hajos, P, Pogatsa, G, Winkler, G, Pardo, I, Barros filho, A, Jahan, S, Huq, F, Biswas, K, Chowdhury, T, Khan, A, Ritterath, C, Talai Rad, N, Siegmund, T, Heinze, T, Henrich, W, Siebert, G, Dudenhausen, J, Buhling, K, Kautzky willer, A, Mustafa, S, Winzer, C, Vukovich, T, Shaat, N, Ekelund, M, Lernmark, Å, Ivarsson, S, Zmudzinska, M, Bronisz, A, Pufal, M, Junik, R, Beran, D, Toledano, Y, Giveon, S, Kahan, E, Aycheh, S, Guttman, N, Jaffe, A, Alberti, H, Boudriga, N, Nabli, M, Jaiveer, S, Jaiveer, P, Shaikh, S, Gopinath, A, Morrissey, J, Patel, V, Lenz, M, Dvoynishnikova, O, Mayorov, A, Galstyan, G, Antsiferov, M, Dedov, I, Rybarczyk, M, Scalone, L, Palmer, A, Morgutti, M, Valentine, W, Renaudin, C, Roze, S, Morsanutto, A, Berto, P, Lopatriello, S, Voinovich, D, Gelisio, R, Brändie, M, Russ, W, Greiner, R, Rodríguez, J, Rubio Terrés, C, De Pablos, P, Smith, I, Morgan, C, Tsutskiridze, L, Haag, B, Delbuono, B, Silva, C, Fox, A, Padilla, V, Naraine, K, Cypryk, K, Szymczak, W, Szosland, K, Sobczak, M, Zawodniak szalapska, M, Lewinski, A, Schvarcz, E, Lindqvist, A, Stenninger, E, Östlund, I, Åman, J, Lapolla, A, Dalfrà, M, Di Benedetto, A, Dolci, M, Franzetti, I, Masotti, M, Napoli, A, Salietti, G, Santini, C, Tortul, C, Di Cianni, G, Popow, C, Waldhör, T, Horn, W, Biermann, E, Rihl, J, Riedl, M, Kastner, P, Kollmann, A, Pusch, W, Schreier, G, Hearnshaw, H, Lowe, P, Griffiths, F, Stapperfend, M, Baehring, T, Cosson, E, Benchimol, M, Carbillon, L, Pariès, J, Lormeau, B, Pharisien, I, Tourel, E, Uzan, M, Attali, J, Zabarovskaya, Z, Mulyarchik, O, Barsukov, A, Guseva, T, Begum, K, Haque, L, Bokor, A, Rigó, J, Garamvölgyi, Z, Pusztai, P, Somogyi, A, Hanson, U, Nyström, L, Blohmó, G, Ekbom schnell, A, Östman, J, Persson, B, Parretti, E, Cioni, R, Marzari, C, Masin, M, Scarselli, G, Mello, G, Seghieri, G, De Bellis, A, Anichini, R, Alviggi, L, Franconi, F, Breschi, C, Dworacka, M, Wender ożegowska, E, Winiarska, H, Macugowska, M, Zawiejska, A, Bobkiewicz kozłowska, T, Pietryga, M, Brązert, J, Bousboulas, S, Politakis, P, Papadimitriou, P, Lyu, R, Yin, D, Green, A, Kristensen, J, Rodríguez saldaña, J, Clark, C, Morales De Teresa, M, Escorza domínguez, A, Ortiz gress, A, Monroy mayorga, A, Mejía pedraza, B, Seeliger, S, Kaiser, J, Müller, E, Maxion bergemann, S, Bergemann, R, Goertz, A, Shearer, A, Bagust, A, Schoeffski, O, Shestakova, M, Balabolkin, M, Chugunova, L, Shamkhalova, M, Zaytseva, N, Naumenkova, I, Brevnova, N, Tsibina, L, Rosak, C, Petzoldt, R, Stammer, H, Dehmel, B, Seidel, D, Roth, W, Fennenkötter, U, Gottschall, V, Kanatsuka, A, Lauenborg, J, Jörgensen, T, Hornnes, P, Wagner, O, Zajdenverg, L, Halfoun, V, Oliveira, J, Lencioni, C, Volpe, L, Chatzianagnostou, K, Cuccuru, I, Ghio, A, Pardini, E, Salvadorini, M, Saltiki, A, Korakovouni, A, Stavrianos, H, Zapanti, E, Antsaklis, A, Pithova, P, Sporna, M, Bustani, R, Todd, D, Guerrero, R, Vázquez, M, Amaya, M, Dios, E, Quijada, D, García hernández, N, Astorga, R, Gandhi, R, Jayawarna, C, Fernando, D, Hill, R, Lloyd mostyn, R, Thomson, G, Rewers, A, Bothner, J, Klingensmith, G, Sysoyeva, O, Karlovich, N, Rankins, D, Wellard, M, Werther, G, Northam, E, Kordonouri, O, Haberland, H, Hauschild, M, Kapellen, T, Kraft, V, Wiemann, D, Lange, K, Witte, D, Laude, D, Dabire, H, Hadj Brahim, F, Papanas, N, Papatheodorou, K, Christakidis, D, Papazoglou, D, Giassakis, G, Piperidou, H, Monastiriotis, H, Maltezos, E, Barrett, C, Serghides, H, Tindali, H, Kelly, F, Chiheb, S, Chen, Q, Brahimi, M, Cynober, L, Delaporte, C, Scionti, L, Conti, M, Vermigli, C, Galimberti, G, Cazzetta, G, Bosi, E, Sugimoto, K, Shoji, M, Yasujima, M, Suda, T, Yagihashi, S, Zsengeller, Z, Charniauskaya, T, Abatan, O, Kimura, I, Tsuneki, H, Hara, S, Sasaki, K, Nangle, M, Gibson, T, Yorek, M, Hirooka, H, Stevens, M, Tarhzaoui, K, Cohen boulakia, F, Smith, G, Lestrade, R, Behar, A, Komori, H, Oi, K, Takahashi, D, Kunitou, T, Moroi, M, Philips, J, Marchand, M, Geronooz, I, Scheen, A, Gambardella, S, Ciampittiello, G, Bracaglia, D, Cicconetti, E, Gigli, F, Verri, C, Baroni, A, Frontoni, S, Szabó, M, Germán, M, Farkas, L, Szentendrei, D, Maiello, M, Mandica, S, Morganti, R, Menzinger, G, Bernardi, L, Aso, Y, Wakabayashi, S, Takebayashi, K, Takemura, Y, Inukai, T, Kalter leibovici, O, Lifshitz, A, Yerushalmy, Y, Stern, E, Ogawa, K, Nanjo, K, Kawamori, R, Katayama, S, Shirai, M, Fonseca, V, Seftel, A, Denne, J, Fredlund, P, Buvat, J, Schmitt, H, Van Ahlen, H, Varanese, L, Lips, J, Hoekstra, J, Banga, J, Legros, J, Lufuma, M, Bouter, K, Fan, L, Lu, J, Zheng, Y, Spruce, M, Jones, C, Coppini, D, Lavery, L, Holtz neiderer, K, Mohler, M, Wendel, C, Nixon, B, Jurado, J, Bataller, F, Dorca, A, Garcia, F, Brossa, N, Barnera, T, Pou Torelló, J, Bregovski, V, Karpova, I, Hedetoft, C, Rasmussen, A, Fabrin, J, Driver, V, Thoms, T, Jeffcoate, W, Monaghan, J, Game, F, Dalla Noce, S, Cimmino, M, Caruso, S, Manes, C, Mikoudi, K, Sossidou, E, Pigas, G, Karagianni, D, Skoutas, D, Fotiadis, S, Pruna, S, Eroshkin, I, Vasiljev, Y, Udovichenko, O, Udovichenko, A, Bondarenko, O, Dang, C, Prasad, Y, Anwar, R, Thomas, G, Lobmann, R, Motzkau, M, Pittasch, D, Lehnert, H, Piaggesi, A, Marsocci, A, Fanara, M, Rizzo, L, Palumbo, F, Campi, F, Tedeschi, A, Scatena, A, Goretti, C, Baicchi, U, Chipchase, S, Treece, K, Pound, N, Hill, N, Cyganek, K, Mirkiewicz sieradzka, B, Malecki, M, Wolkow, P, Skupien, J, Naskalska, A, Sieradzki, J, Tapp, R, Tonkin, A, Harper, A, Mccarty, D, Söderberg, S, Taylor, H, Chitson, P, Alberti, G, Sheetz, M, Aiello, L, Davis, M, Milton, R, Arora, V, Hu, K, Girach, A, Vignati, L, Tyrberg, M, Melander, A, Lindblad, U, Giannarelli, R, Coppelli, A, Sartini, M, Aragona, M, Fletcher, E, Ninkovic, S, Foster, L, Jones, D, De Gooyer, T, Stitt, A, Vingrys, A, Wilkinson berka, J, Lewandowska, A, Randeva, H, Komorowski, J, Lewandowski, K, Jurowski, P, Sankar, S, Gos, R, Kowluru, R, Odenbach, S, Shinn, S, Agardh, C, Hultberg, B, Segura, R, Fonollosa, A, Berrone, E, Beltramo, E, Solimine, C, Ubertalli, A, Islam, N, Esteve, E, Fernandez, M, Recas, I, Mauri, S, Biarnes, F, Junca, E, Fernádez real, J, Rössner, S, Stenlof, K, Levy, B, Perry, B, Fitchet, M, Chrysos, G, Kamaratos, A, Lepeniotis, G, Kokkoris, S, Varytimiadis, K, Stasini, F, Mikros, S, Gianneli, D, Tryfinopoulou, K, Melidonis, A, Nikolopoulou, C, Harley, K, Ryder, R, De, P, Vannieuwenhoven, F, Rossing, K, Oliver, N, Goldschmeding, R, Jacobsen, P, Tan, F, Liew, S, Mukherjee, J, Lim, P, Fröjdö, S, Sjölind, L, Parkkonen, M, Mäkinen, V, Tikellis, C, Nieuwenhoven, F, Macisaac, R, Tsalamandris, C, Mcneil, K, Panaiotopoulos, S, Smith, T, Ho, M, Matthews, P, Jerums, G, Hut, H, Van Den Meiracker, A, Nakhjavani, M, Behjati, J, Esteghamati, A, Esfahanian, F, Aghamohamadzadeh, N, Abbasi, M, Kohnert, K, Zander, E, Krabbe, S, Stehouwer, C, Schalkwijk, C, Krarup Hansen, T, Teppo, A, Ebeling, P, Abdella, N, Mojiminiyi, O, Al Dahi, W, Al Mohammedi, H, Al Jebely, S, Neugebauer baba, S, Baba, T, Ohashi, H, Nakajima, S, Hesselmann, C, Watanabe, T, Nargis, M, Zaid, R, Voronko, O, Tchugunova, L, Vikulova, O, Nosikov, V, Liu, L, Zheng, T, Li, M, Zhang, R, Xiang, K, Hadjadj, S, Jeunemaitre, X, Vervoort, G, Veldman, B, Berden, J, Wetzels, J, Singh, B, Holland, M, Baskar, V, Oh, J, Seo, J, Choi, K, Baik, S, Choi, D, Kim, N, Matsumoto, S, Suetsugu, M, Matsutomo, R, Pisarczyk wiza, D, Banaszak, A, Wysocki, H, Usui, H, Shikata, K, Okada, S, Ogawa, D, Yozai, K, Kido, Y, Nagase, R, Ohga, S, Tone, A, Sasaki, M, Wada, J, Unno, Y, Horiuchi, S, Mclennan, S, Kamarinos, M, Waltham, M, Dy, V, Yue, D, Zdychova, J, Komers, R, Cresci, B, Giannini, S, Manuelli, C, Giunti, S, Pinach, S, Ianni Palarchio, A, Arnaldi, L, Vittone, F, Camussi, G, Cavallo Perin, P, Gruden, G, Marshall, S, Jones, S, White, K, Brizzi, M, Dentelli, P, Rosso, A, Calvi, C, Gambino, R, Cassader, M, Salvidio, G, Deferrari, G, Pegoraro, L, Pagano, G, Cavallo perin, P, Oates, R, Ellery, C, Beebe, D, Coutcher, J, Qian, Y, Lowe, V, Appleton, T, Raunig, D, O'Neil, S, Mylari, B, Amazonas, R, Fujita, A, Doi, A, Matsuno, S, Okamoto, K, Matsumoto, E, Furuta, H, Nishi, M, Tsuno, T, Taniguchi, H, Bessho, H, Wasén, E, Isoaho, R, Mattila, K, Vahlberg, T, Kivelä, S, Irjala, K, Rigalleau, V, Lasseur, C, Perlemoine, C, Barthes, N, Raffaitin, C, Chauveau, P, Combe, C, Baillet blanco, L, Beauvieux, M, Gin, H, Heinrich, S, Steiner, T, Ott, U, Holdass, H, Fellström, B, Jardine, A, Staffler, B, Logan, J, Gimpelewicz, C, Stanciu, C, Pena, C, Serafinceanu, C, González posada, J, Hernández, D, Pérez tamajó, L, Ló, A, Herná Alarcó, M, Meneses, M, Barsotti, M, Rizzo, G, Schmauss, S, Havrdova, T, Saudek, F, Boucek, P, Adamec, M, Invitti, C, Gilardini, L, Parati, G, Mazzilli, G, Pontiggia, B, Sartorio, A, Lutgers, H, Groenier, K, Zasadzinska, G, Saryusz wolska, M, Kurktschiev, D, Majdrakova, I, Varbanova, T, Todorova, B, Bajo martinez, A, Bernal, E, Sanchez, O, Ugalde canitrot, A, Sanchez largo, E, Coca robinot, D, Fabregate, R, Calbacho, M, Marquez, J, Saban ruiz, J, Penesova, A, Cizmarova, E, Blazicek, P, De Jongh, R, Serné, E, Ijzerman, R, De Vries, G, Andersen, N, Knudsen, S, Helleberg, K, Mogensen, C, Waluś, M, Idzior waluś, B, Sztefko, K, Cieślik, G, Fedak, D, Wozniakiewicz, E, Lin, S, Guo, M, Lin, C, Liu, X, Francisco, M, Rodriguez rosas, H, Peiró martinez, I, Macías batista, A, Harte, A, Rodriguez cuenca, S, Valsamakis, G, Chetty, R, Anderson, L, Roca, P, Matyka, K, Lasalle, J, Hershon, K, Berman, L, Gibson, E, Gillen, D, Maroni, J, Simmons, D, Hiukka, A, Forder, P, Leinonen, E, Hilden, H, Fruchart, J, Keech, A, Farnier, M, Freeman, M, Macdonell, G, Perevozskaya, I, Mitchel, Y, Gumbiner, B, Didangelos, T, Athyros, V, Mikhailidis, D, Papageorgiou, A, Bouloukos, V, Pehlivanidis, A, Symeonidis, A, Elisaf, M, Mckenney, J, Insull, W, Lewin, A, Maccubbin, D, Kush, D, Schuster, H, Barter, P, Stender, S, Bonnet, J, Morrell, J, Watkins, C, Kallend, D, Stalenhoef, A, Ballantyne, C, Murin, J, Tonstad, S, Rose, H, Wilpshaar, W, Jenkins, A, Karschimkus, C, Dragicevic, G, Rowley, K, Wolthers, T, Best, J, Voet, B, Murdoch, S, Marcovina, S, Brunzell, J, Caparevic, Z, Kostic, N, Ilic, S, Sartore, G, Piarulli, F, Cantaro, S, Reitano, R, Fiore, C, Marin, R, Bassan, S, Manzato, E, Fedele, D, Solini, A, Santini, E, Thornalley, P, Babaei jadidi, R, Karachalias, N, Kupich, C, Ahmed, N, Fowler, A, Baker, A, Starczynski, J, O'Hare, P, Szepietowska, B, Szelachowska, M, Puch, U, Glebocka, A, Quinn, D, Mcternan, C, Bonser, R, Idzior walus, B, Woźniakiewicz, E, Dimitriou, K, Apostolou, O, Kontela, E, Devangelio, E, Gould, E, Serri, O, Roussin, A, Buithieu, J, Mamputu, J, Renier, G, Giordanetti, S, De Amici, E, Poggi, G, Turpini, C, Fratino, P, Garzaniti, A, Banu, I, Paries, J, Roman, G, Negrean, M, Bala, C, Nita, C, Kistorp, C, Gustafsson, F, Chong, A, Lip, G, Galatius, S, Ari, N, Sahilli, M, Ceylan isık, A, Ozansoy, G, Karasu yilmaz, C, Matteucci, E, Rosada, J, Pallini, M, Evangelista, I, Cassetti, G, Giusti, C, Giampietro, O, Capaldo, B, Galderisi, M, Cicala, S, Turco, A, Imbroinise, A, Nosso, G, D'Errico, A, De Divitiis, O, Klimontov, V, Korolyova, E, Jeltova, L, Bondar, I, Tarkun, I, Arslan, B, Canturk, Z, Tarkun, P, Agacdiken, A, Komsuoglu, B, Méneveau, N, Pierre justin, E, Alsayed, M, Sabbah, R, Paulin, S, Marcu, S, Tauveron, I, Zimmermann, C, Schiele, F, Seronde, M, Vautrin, P, Lusson, J, Thieblot, P, Bernard, Y, Mistry, A, Pye, M, Peovska, I, Maksimovic Pavlovic, J, Vavlukis, M, Pop Gorceva, D, Bosevski, M, Scognamiglio, R, Negut, C, De Kreutzenberg, S, Madonna, R, De Caterina, R, Willerson, J, Geng, Y, Vahsen, S, Ledwig, D, Ramrath, S, Frantz, S, Schmidt, I, Calvillo, L, Dienesch, C, Elbing, I, Bischoff, H, Ertl, G, Bauersachs, J, Davydov, A, Mkrtum'Yan, A, Baranova, L, Ikeda, Y, Suehiro, T, Osaki, F, Ota, K, Arii, K, Kumon, Y, Hashimoto, K, Doney, A, Morris, A, Palmer, C, Byun, S, Doo, H, Pagnin, E, Calo, L, Fadini, G, Kubaszek, A, Chai, S, Chai, Q, Rasmussen, L, Ledet, T, Wogensen, L, Lengyel, C, Varró, A, Virág, L, Magyar, J, Bíró, T, Jost, N, Skoumal, R, Nánási, P, Tóth, M, Horkay, F, Papp, J, Zacharopoulou, O, Athanaselis, S, Tsokos, N, Doupis, J, Psallas, M, Cokkinos, D, Pavlatos, S, Liatis, S, Akhobadze, T, Dzneladze, L, Samarguliani, I, Taskiran, M, Rasmussen, V, Jensen, G, Fisher, A, Petrovsky, N, Srikusalanukul, W, Budge, M, Trifunovic zamaklar, D, Zivkovic, M, Jelic, V, Vukomanovic, G, Ristic, A, Seferovic, P, Costa, J, Duarte, S, Manley, S, Sailesh, S, Venkataraman, A, Haider, Y, Groza, I, Oprean, M, Ardelean, A, Morosanu, A, Darkow, T, Vanderplas, A, Mamas, M, Mcelduff, P, Burns, J, Edwards, R, Fitchet, A, Young, R, Gibson, J, Lichiardopol, R, Niculescu, N, Totora, A, Pencea, C, Tomescu, I, Cinteza, M, Manicardi, V, Coscelli, C, Navazio, A, Catellani, E, Michelini, M, Dall'Asta, D, Guberti, A, Piazza, A, Gasparini, E, Pantaleoni, M, Guiducci, U, Manari, A, Sejil, S, Janand delenne, B, Avierinos, J, Habib, G, Labastie, N, Vague, P, Lassmann vague, V, Luźniak, P, Tatoń, J, Wojciechowska Luźniak, A, Zairis, M, Lyras, A, Patsourakos, N, Tsirimbis, V, Foussas, S, Lupón, J, Urrutia, A, Herreros, J, González, B, Coll, R, Altimir, S, Prats, M, Valle, V, Abreu padí, C, Rábago, G, Ivanova, L, Brasacchio, D, Harno, E, Keenan, A, Li, H, Lu, Z, Ke, L, Liu, H, Jeong, I, Chae, M, Choi, M, Yoo, H, Kim, C, Yun, M, Na, M, Kang, Y, Kong, O, Son, S, Kim, I, Tanaka, N, Hosoi, M, Matsuyama, Y, Fukumoto, M, Yamakita, T, Yoshioka, K, Ishii, T, Sato, T, Fujii, S, Aoki, T, Shibata, T, Mizutani, N, Suzuki, J, Fowelin, J, Samuelsson, P, Brandrup wogsen, G, Okumura, K, Tokmakova, A, Staroverova, D, Antcieferov, M, Shutichina, I, Kuntchevich, G, Vriesendorp, T, Morélis, Q, Legemate, D, Schaper, F, Mainas, E, Gkioulmpasanis, I, Panagiotou, I, Vassilikos, G, Skorda, L, Sidira, M, Christoforidou, M, Alaveras, A, Artikis, V, Evdemon, E, Lechleitner, M, Koch, T, Ebenbichler, C, Sturm, W, Moretti, L, Moruzzo, D, Boldrini, E, Pandolfo, C, Kameyama, M, Iwasa, R, Cho, M, Nam, J, Huh, K, Kaplar, M, Paragh, G, Erdei, A, Csongradi, E, Garai, I, Varga, J, Galuska, L, Udvardy, M, Higa, M, Kaneko, Y, Hiroi, N, Koziarska, D, Nowacki, P, Majkowska, L, Luzniak, P, Wojciechowska luźniak, A, Tushuizen, M, Nieuwland, R, Snoeck, D, Sturk, A, Diamant, M, Aguiar, L, Bahia, L, Villela, N, Laflor, C, Conde, C, Bottino, D, Dorigo, D, Bouskela, E, Pu, S, Luo, Z, Lam, K, Dan, Q, Xu, A, Shen, J, Cheng, K, Xu, J, Thamer, C, Stefan, N, Haap, M, Heller, E, Tschritter, O, De Prado, A, Ortiz, A, Ybarra, J, Gich, I, Pou, J, Ehren, M, Roggenland, D, Reinsen, B, Klein, H, Rittig, K, Stock, J, Kocher, B, Balletshofer, B, Shon, H, Chung, D, Nakatani, Y, Matsuhisa, M, Kaneto, H, Hatazaki, M, Yoshiuchi, K, Katakami, N, Kawamori, D, Ohtoshi, K, Sakamoto, K, Matsuoka, T, Ozawa, K, Ogawa, S, Hori, M, Yamasaki, Y, Zitouni, K, Harry, D, Nourooz zadeh, J, Earle, K, Olesen, P, Franco, L, Corvaja, C, Semplicini, A, Ceylan işık, A, Arı, N, Rösen, P, Lee, I, Park, K, Jung, E, Shin, D, Jo, S, Obuobie, K, Prakash, P, Hanna, F, Lazarus, J, Varadhan, L, Gurushankar, J, James, D, Sheikh, S, Gaede, P, Zou, D, Vilarrasa, N, Perez maraver, M, Mena, E, Perez, D, Setti, G, Buckingham, R, Urbančič, V, Stefanovska, A, Bernjak, A, Ažman juvan, K, Kocijančič, A, Glowania, A, Filters, T, Fosmark, D, Torjesen, P, Kilhovd, B, Berg, T, Sandvik, L, Hanssen, K, Mentink, C, Donchenko, G, Stepanenko, S, Maingrette, F, Deng, H, Lindenmair, A, Freudenthaler, A, Baumgartner parzer, S, Nizheradze, K, Khoruzhenko, A, Tronko, N, Sheu, W, Ou, H, Shen, H, Lin, T, Wu, H, Yang, C, Mogylnytska, L, Schmoelzer, I, Davies, J, Band, M, Struthers, A, Prázný, M, Škrha, J, Kasalová, Z, Neelotpol, S, Jahan, P, Kauschke, S, Harrop, C, Schäfer, A, Widder, J, Eigenthaler, M, Walter, U, Uchimura, I, Ikebukuro, M, Kaibara, M, Hirata, M, Helal, R, Pervin, F, Yang, X, Jansson, P, Nagaev, I, Jack, M, Carvalho, E, Sunnerhagen, K, Cam, M, Cushman, S, Smith, U, Creely, S, Farmer, J, Gustafson, B, Kusminski, C, Krusinova, E, Wohl, P, Klementova, M, Lanska, V, Mcdougall, C, Kelly, I, Abbas, Z, Lutale, J, Archibald, L, Karunajeewa, H, Stingemore, N, Stuccio, G, Mcgechie, D, Muller, L, Hak, E, Goudzwaard, W, Montorsi, F, Homering, M, Sprenger, K, Goldstein, I, Asnaghi, V, Ferrari, G, Rastaldi, M, Gabellini, D, Dell'Antonio, G, Maestroni, A, Ruggieri, D, Luzi, L, Piemonti, L, Zerbini, G, Anafaroglu, I, Tutuncu, N, Sultana, M, Siddiqua, N, Iwasaki, T, Nakajima, A, Yoneda, M, Mukasa, K, Tanaka, S, and Sekihara, H
- Subjects
0303 health sciences ,medicine.medical_specialty ,business.industry ,EASD ,Endocrinology, Diabetes and Metabolism ,Human physiology ,medicine.disease ,03 medical and health sciences ,0302 clinical medicine ,Diabetes mellitus ,Family medicine ,Internal Medicine ,Medicine ,business ,030217 neurology & neurosurgery ,030304 developmental biology - Published
- 2004
31. Respiratory Syncytial Virus-Associated Respiratory Diseases in Children and Adults.
- Author
-
Tenenbaum T, Liese J, Welte T, and Rademacher J
- Subjects
- Humans, Adult, Female, Infant, Child, Infant, Newborn, Respiratory Syncytial Virus Vaccines therapeutic use, Child, Preschool, Male, Risk Factors, Respiratory Tract Infections epidemiology, Respiratory Tract Infections prevention & control, Respiratory Tract Infections virology, Pregnancy, Respiratory Syncytial Virus Infections prevention & control, Respiratory Syncytial Virus Infections epidemiology
- Abstract
Background: Respiratory syncytial virus (RSV) is a common cause of lower respiratory tract infections (LRTI), particularly in neonates, infants and young children, with approximately 33 million infections worldwide each year. 1-2% of episodes lead to hospitalization. There are hardly any reliable epidemiological figures on hospital - ization in adults, whose burden of disease from RSV is probably markedly underestimated., Methods: This review is based on publications retrieved by a selective search in PubMed, with particular attention to recommendations for the prevention of RSV infection., Results: There is no approved antiviral therapy for clinical practice, but preventive strategies are increasingly becoming available. Passive immunization in infants is well tolerated and highly effective, as is the active vaccination of pregnant women to prevent severe RSV infection in young infants. The former was found to lower the frequency of severe LRTI (5/4037 in the vaccination group vs. 19/4031 individuals in the placebo group), yielding an efficacy of 75.7%; for the latter, the corresponding findings were a reduction to 19/3682 in the vaccination group vs. 62/3676 in the placebo group, or 69.4% efficacy. For the active vaccination of older adults, both a recombinant vaccine with adjuvant and a bivalent vaccine have recently been approved. These, too, are well tolerated and highly effective: the former lowered the frequency of severe LRTI to 1/12466 in the vaccination group vs. 17/12494 in the placebo group (94.1% efficacy), while the latter lowered the frequency of LRTI with 3 or more manifestations to 2/17215 in the vaccination group vs. 14/17069 in the placebo group (85.7% efficacy)., Conclusion: The approval of new RSV-specific monoclonal antibodies and active vaccinations enables targeted prevention of RSV infection in the main population groups at risk.
- Published
- 2024
- Full Text
- View/download PDF
32. Epidemiology of 7375 children and adolescents hospitalized with COVID-19 in Germany, reported via a prospective, nationwide surveillance study in 2020-2022.
- Author
-
Doenhardt M, Hufnagel M, Diffloth N, Hübner J, Mauer R, Schneider DT, Simon A, Tenenbaum T, Trotter A, Armann J, and Berner R
- Subjects
- Infant, Child, Pregnancy, Female, Humans, Adolescent, Child, Preschool, SARS-CoV-2, Prospective Studies, Hospitalization, Germany epidemiology, Obesity, COVID-19 epidemiology, Pregnancy Complications, Infectious epidemiology
- Abstract
By means of a nationwide, prospective, multicenter, observational cohort registry collecting data on 7375 patients with laboratory-confirmed SARS-CoV-2 admitted to children's hospitals in Germany, March 2020-November 2022, our study assessed the clinical features of children and adolescents hospitalized due to SARS-CoV-2, evaluated which of these patients might be at highest risk for severe COVID-19, and identified underlying risk factors. Outcomes tracked included: symptomatic infection, case fatality, sequelae at discharge and severe disease. Among reported cases, median age was one year, with 42% being infants. Half were admitted for reasons other than SARS-CoV-2. In 27%, preexisting comorbidities were present, most frequently obesity, neurological/neuromuscular disorders, premature birth, and respiratory, cardiovascular or gastrointestinal diseases. 3.0% of cases were admitted to ICU, but ICU admission rates varied as different SARS-CoV-2 variants gained prevalence. Main risk factors linked to ICU admission due to COVID-19 were: patient age (> 12 and 1-4 years old), obesity, neurological/neuromuscular diseases, Trisomy 21 or other genetic syndromes, and coinfections at time of hospitalization. With Omicron, the group at highest risk shifted to 1-4-year-olds. For both health care providers and the general public, understanding risk factors for severe disease is critical to informing decisions about risk-reduction measures, including vaccination and masking guidelines., (© 2023. The Author(s).)
- Published
- 2024
- Full Text
- View/download PDF
33. Immunization technologies: Time to consider new preventative solutions for respiratory syncytial virus infections.
- Author
-
Weil-Olivier C, Salisbury D, Navarro-Alonso JA, Tzialla C, Zhang Y, Esposito S, Midulla F, and Tenenbaum T
- Subjects
- Infant, Humans, Immunization, Vaccination, Antibodies, Monoclonal, Immunization, Passive, Respiratory Syncytial Virus Infections prevention & control, Respiratory Syncytial Virus, Human, Communicable Diseases
- Abstract
New technologies for the prevention of infectious diseases are emerging to address unmet medical needs, in particular, the use of long-acting monoclonal antibodies (mAb) to prevent Respiratory Syncytial Virus (RSV) lower respiratory tract disease in infants during their first RSV season. The lack of precedent for mAbs for broad population protection creates challenges in the assessment of upcoming prophylactic long-acting mAbs for RSV, with associated consequences in legislative and registration categorization, as well as in recommendation, funding, and implementation pathways. We suggest that the legislative and regulatory categorization of preventative solutions should be decided by the effect of the product in terms of its impact on the population and health-care systems rather than by the technology used or its mechanism of action. Immunization can be passive and active, both having the same objective of prevention of infectious diseases. Long-acting prophylactic mAbs work as passive immunization, as such, their recommendations for use should fall under the remit of National Immunization Technical Advisory Groups or other relevant recommending bodies for inclusion into National Immunization Programs. Current regulations, policy, and legislative frameworks need to evolve to embrace such innovative preventative technologies and acknowledge them as one of key immunization and public health tools.
- Published
- 2023
- Full Text
- View/download PDF
34. Correction to: The choroid plexus acts as an immune cell reservoir and brain entry site in experimental autoimmune encephalomyelitis.
- Author
-
Lazarevic I, Soldati S, Mapunda JA, Rudolph H, Rosito M, de Oliveira AC, Enzmann G, Nishihara H, Ishikawa H, Tenenbaum T, Schroten H, and Engelhardt B
- Published
- 2023
- Full Text
- View/download PDF
35. The choroid plexus acts as an immune cell reservoir and brain entry site in experimental autoimmune encephalomyelitis.
- Author
-
Lazarevic I, Soldati S, Mapunda JA, Rudolph H, Rosito M, de Oliveira AC, Enzmann G, Nishihara H, Ishikawa H, Tenenbaum T, Schroten H, and Engelhardt B
- Subjects
- Animals, Mice, Choroid Plexus physiology, Neuroinflammatory Diseases, Brain, Central Nervous System, Mice, Inbred C57BL, Encephalomyelitis, Autoimmune, Experimental
- Abstract
The choroid plexus (ChP) has been suggested as an alternative central nervous system (CNS) entry site for CCR6
+ Th17 cells during the initiation of experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis (MS). To advance our understanding of the importance of the ChP in orchestrating CNS immune cell entry during neuroinflammation, we here directly compared the accumulation of CD45+ immune cell subsets in the ChP, the brain and spinal cord at different stages of EAE by flow cytometry. We found that the ChP harbors high numbers of CD45int resident innate but also of CD45hi adaptive immune cell subsets including CCR6+ Th17 cells. With the exception to tissue-resident myeloid cells and B cells, numbers of CD45+ immune cells and specifically of CD4+ T cells increased in the ChP prior to EAE onset and remained elevated while declining in brain and spinal cord during chronic disease. Increased numbers of ChP immune cells preceded their increase in the cerebrospinal fluid (CSF). Th17 but also other CD4+ effector T-cell subsets could migrate from the basolateral to the apical side of the blood-cerebrospinal fluid barrier (BCSFB) in vitro, however, diapedesis of effector Th cells including that of Th17 cells did not require interaction of CCR6 with BCSFB derived CCL20. Our data underscore the important role of the ChP as CNS immune cell entry site in the context of autoimmune neuroinflammation., (© 2023. The Author(s).)- Published
- 2023
- Full Text
- View/download PDF
36. Antimicrobial use in pediatric oncology and hematology in Germany and Austria, 2020/2021: a cross-sectional, multi-center point-prevalence study with a multi-step qualitative adjudication process.
- Author
-
Papan C, Reifenrath K, Last K, Attarbaschi A, Graf N, Groll AH, Hübner J, Laws HJ, Lehrnbecher T, Liese JG, Martin L, Tenenbaum T, Vieth S, von Both U, Wagenpfeil G, Weichert S, Hufnagel M, and Simon A
- Abstract
Background: Due to the high risk of severe infection among pediatric hematology and oncology patients, antimicrobial use is particularly high. With our study, we quantitatively and qualitatively evaluated, based on institutional standards and national guidelines, antimicrobial usage by employing a point-prevalence survey with a multi-step, expert panel approach. We analyzed reasons for inappropriate antimicrobial usage., Methods: This cross-sectional study was conducted at 30 pediatric hematology and oncology centers in 2020 and 2021. Centers affiliated to the German Society for Pediatric Oncology and Hematology were invited to join, and an existing institutional standard was a prerequisite to participate. We included hematologic/oncologic inpatients under 19 years old, who had a systemic antimicrobial treatment on the day of the point prevalence survey. In addition to a one-day, point-prevalence survey, external experts individually assessed the appropriateness of each therapy. This step was followed by an expert panel adjudication based upon the participating centers' institutional standards, as well as upon national guidelines. We analyzed antimicrobial prevalence rate, along with the rate of appropriate, inappropriate, and indeterminate antimicrobial therapies with regard to institutional and national guidelines. We compared the results of academic and non-academic centers, and performed a multinomial logistic regression using center- and patient-related data to identify variables that predict inappropriate therapy., Findings: At the time of the study, a total of 342 patients were hospitalized at 30 hospitals, of whom 320 were included for the calculation of the antimicrobial prevalence rate. The overall antimicrobial prevalence rate was 44.4% (142/320; range 11.1-78.6%) with a median antimicrobial prevalence rate per center of 44.5% (95% confidence interval [CI] 35.9-49.9). Antimicrobial prevalence rate was significantly higher (p < 0.001) at academic centers (median 50.0%; 95% CI 41.2-55.2) compared to non-academic centers (median 20.0%; 95% CI 11.0-32.4). After expert panel adjudication, 33.8% (48/142) of all therapies were labelled inappropriate based upon institutional standards, with a higher rate (47.9% [68/142]) when national guidelines were taken into consideration. The most frequent reasons for inappropriate therapy were incorrect dosage (26.2% [37/141]) and (de-)escalation/spectrum-related errors (20.6% [29/141]). Multinomial, logistic regression yielded the number of antimicrobial drugs (odds ratio, OR, 3.13, 95% CI 1.76-5.54, p < 0.001), the diagnosis febrile neutropenia (OR 0.18, 95% CI 0.06-0.51, p = 0.0015), and an existing pediatric antimicrobial stewardship program (OR 0.35, 95% CI 0.15-0.84, p = 0.019) as predictors of inappropriate therapy. Our analysis revealed no evidence of a difference between academic and non-academic centers regarding appropriate usage., Interpretation: Our study revealed there to be high levels of antimicrobial usage at German and Austrian pediatric oncology and hematology centers with a significant higher number at academic centers. Incorrect dosing was shown to be the most frequent reason for inappropriate usage. Diagnosis of febrile neutropenia and antimicrobial stewardship programs were associated with a lower likelihood of inappropriate therapy. These findings suggest the importance of febrile neutropenia guidelines and guidelines compliance, as well as the need for regular antibiotic stewardship counselling at pediatric oncology and hematology centers., Funding: European Society of Clinical Microbiology and Infectious Diseases, Deutsche Gesellschaft für Pädiatrische Infektiologie, Deutsche Gesellschaft für Krankenhaushygiene, Stiftung Kreissparkasse Saarbrücken., Competing Interests: AA reports having received payments or honoraria by Saarland University (Homburg). HJL reports having received payments or honoraria by CSL Behring, and support for attending meetings and/or travel by Pfizer, Roche, Bayer, Sobi, and CSL Behring. TL reports having received consulting fees by Gilead Sciences, Merck/MSD, Pfizer, Mundipharma, Roche; and payments or honoraria by Merck/MSD, Sanofi, Gilead Sciences, and Pfizer. LM reports being on the advisory board of and having received payments by Shionogi, and having received payments or honoraria by the German Pediatric Society for Infectious Diseases and the Professional Association of Pediatricians. The remaining authors declare no conflicts of interest., (© 2023 The Author(s).)
- Published
- 2023
- Full Text
- View/download PDF
37. Burden of Pediatric SARS-CoV-2 Hospitalizations during the Omicron Wave in Germany.
- Author
-
Doenhardt M, Gano C, Sorg AL, Diffloth N, Tenenbaum T, von Kries R, Berner R, and Armann JP
- Subjects
- Adolescent, Child, Humans, Hospitalization, Germany epidemiology, SARS-CoV-2, COVID-19 epidemiology
- Abstract
(1) Background: When the Omicron variant of SARS-CoV-2 first emerged in Germany in January 2022, data on related disease severity among children and adolescents were not yet available. Given Omicron's high transmissibility, the ability to assess its impact on admission and hospitalization rates in children's hospitals is critical for the purpose of understanding the scope of its burden on the German healthcare system. (2) Methods: From 24 January 2022 to 31 July 2022, SARS-CoV-2 cases admitted to German pediatric hospitals were monitored via a national, clinician-led reporting system (CLRS) established by the German Society for Pediatric Infectious Diseases (DGPI). Cases treated on general wards and intensive care units, as well as patient age and the need for respiratory support, were recorded. (3) Results: From January to July 2022, a median of 1.7 cases (range 0.4-3) per reporting pediatric hospital per day was hospitalized in general wards, whereas a median of 0.1 cases (range 0-0.4 cases) was admitted to intensive care units. Of all hospitalized patients, 4.2% received respiratory support. (4) Conclusions: Despite the high incidence rates documented in connection with the Omicron variant in early 2022, the number of pediatric hospital admissions, and especially the number of cases with the need for intensive care treatment and respiratory support due to symptomatic SARS-CoV-2 infection, remained relatively low. Higher Omicron incidence rates had only a modest impact on SARS-CoV-2-related admissions and hospitalization in German children's hospitals.
- Published
- 2022
- Full Text
- View/download PDF
38. Antimicrobial Use in Pediatric Oncology and Hematology: Protocol for a Multicenter Point-Prevalence Study With Qualitative Expert Panel Assessment.
- Author
-
Papan C, Reifenrath K, Last K, Attarbaschi A, Graf N, Groll AH, Huebner J, Laws HJ, Lehrnbecher T, Liese J, Martin L, Tenenbaum T, Weichert S, Vieth S, von Both U, Hufnagel M, and Simon A
- Abstract
Background: Because infections are a major driver of morbidity and mortality in children with hematologic or oncologic diseases, antimicrobials are frequently prescribed in pediatric oncology practice. However, excess or inappropriate use of antimicrobials is directly linked to the emergence of antimicrobial resistance. Although point-prevalence studies have examined the extent of antimicrobial use, a comprehensive qualitative evaluation of individual antimicrobial prescriptions remains lacking., Objective: The aim of this study is to identify appropriate versus inappropriate antimicrobial use among pediatric cancer patients in a point-prevalence study, followed by an expert panel adjudication process and a subsequent report of these findings to participating centers. This study also aims to improve the quality of patient care by informing centers about discrepancies between internal standards of care and national guidelines., Methods: Our point-prevalence study is performed at pediatric cancer centers in Germany and Austria. All patients under 18 years old who are hospitalized at the time of the study are included. As a supplement to the point-prevalence study, an expert panel is qualitatively assessing each of the antimicrobial prescriptions at the participating centers to review local guidelines and compare them with national guidelines., Results: As of December 2021, the point-prevalence survey has been conducted at 30 sites and expert panel adjudication for qualitative assessment of each antimicrobial use is ongoing. Results of the study are expected in 2022., Conclusions: This is the first point-prevalence study conducted among pediatric cancer centers with an integrated, multistep, qualitative approach that assesses each antimicrobial prescription. The results of this study will inform possible interventions for internal guidelines and antimicrobial stewardship programs implemented at pediatric cancer centers. In addition, local guidelines will be compared with national guidelines. Furthermore, this study will contribute to the overall integration of antimicrobial stewardship principles and initiatives in pediatric oncology and hematology, thereby improving safety and quality of care for children and adolescents with cancer and blood disorders., International Registered Report Identifier (irrid): DERR1-10.2196/35774., (©Cihan Papan, Katharina Reifenrath, Katharina Last, Andishe Attarbaschi, Norbert Graf, Andreas H Groll, Johannes Huebner, Hans-Jürgen Laws, Thomas Lehrnbecher, Johannes Liese, Luise Martin, Tobias Tenenbaum, Stefan Weichert, Simon Vieth, Ulrich von Both, Markus Hufnagel, Arne Simon. Originally published in JMIR Research Protocols (https://www.researchprotocols.org), 20.06.2022.)
- Published
- 2022
- Full Text
- View/download PDF
39. A host signature based on TRAIL, IP-10, and CRP for reducing antibiotic overuse in children by differentiating bacterial from viral infections: a prospective, multicentre cohort study.
- Author
-
Papan C, Argentiero A, Porwoll M, Hakim U, Farinelli E, Testa I, Pasticci MB, Mezzetti D, Perruccio K, Etshtein L, Mastboim N, Moscoviz E, Ber TI, Cohen A, Simon E, Boico O, Shani L, Gottlieb TM, Navon R, Barash E, Oved K, Eden E, Simon A, Liese JG, Knuf M, Stein M, Yacobov R, Bamberger E, Schneider S, Esposito S, and Tenenbaum T
- Subjects
- Anti-Bacterial Agents therapeutic use, Apoptosis, Biomarkers, C-Reactive Protein analysis, Chemokine CXCL10, Child, Child, Preschool, Cohort Studies, Diagnosis, Differential, Female, Humans, Ligands, Male, Prospective Studies, Bacterial Infections microbiology, Virus Diseases diagnosis
- Abstract
Objectives: Identifying infection aetiology is essential for appropriate antibiotic use. Previous studies have shown that a host-protein signature consisting of TNF-related apoptosis-induced ligand (TRAIL), interferon-γ-induced protein-10 (IP-10), and C-reactive protein (CRP) can accurately differentiate bacterial from viral infections., Methods: This prospective, multicentre cohort study, entitled AutoPilot-Dx, aimed to validate signature performance and to estimate its potential impact on antibiotic use across a broad paediatric population (>90 days to 18 years) with respiratory tract infections, or fever without source, at emergency departments and wards in Italy and Germany. Infection aetiology was adjudicated by experts based on clinical and laboratory investigations, including multiplex PCR and follow-up data., Results: In total, 1140 patients were recruited (February 2017-December 2018), of which 1008 met the eligibility criteria (mean age 3.5 years, 41.9% female). Viral and bacterial infections were adjudicated for 628 (85.8%) and 104 (14.2%) children, respectively; 276 patients were assigned an indeterminate reference standard outcome. For the 732 children with reference standard aetiology, the signature discriminated bacterial from viral infections with a sensitivity of 93.7% (95%CI 88.7-98.7), a specificity of 94.2% (92.2-96.1), positive predictive value of 73.0% (65.0-81.0), and negative predictive value of 98.9% (98.0-99.8); in 9.8% the test results were equivocal. The signature performed consistently across different patient subgroups and detected bacterial immune responses in viral PCR-positive patients., Conclusions: The findings validate the high diagnostic performance of the TRAIL/IP-10/CRP signature in a broad paediatric cohort, and support its potential to reduce antibiotic overuse in children with viral infections., (Copyright © 2021 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
- Published
- 2022
- Full Text
- View/download PDF
40. Respiratory Tract Infections in Children.
- Author
-
Tenenbaum T
- Abstract
Respiratory tract infections are a major threat, causing morbidity and mortality, especially among children [...].
- Published
- 2021
- Full Text
- View/download PDF
41. General Characteristics of Children with Single- and Co-Infections and Febrile Seizures with a Main Focus on Respiratory Pathogens: Preliminary Results.
- Author
-
Rudolph H, Gress K, Weiss C, Schroten H, Adams O, and Tenenbaum T
- Abstract
Febrile seizures (FS) affect up to 5% of children. The pathogen etiology in regard of viral loads has never been investigated. In a prospective cohort study we investigated the correlation between virus type and quantity in nasopharyngeal aspirates (NPAs) and the clinical characteristics in pediatric patients with a FS. From January 2014 to April 2016, 184 children with a FS were prospectively enrolled. The mean age of all included children was 26.7 ± 18.3 months with a male to female ratio of 1.4:1. Males with an acute disease and a short duration or absence of prior symptoms had a higher risk for complex FS. The majority of patients with FS presented with a generalized convulsion (180; 98%) and was admitted to hospital (178; 97%). Overall, 79 (43%) single and in 59 (32%) co-infections were detected. Human herpes virus 6 (HHV6), influenza, adenovirus (AV) and rhinovirus (RV) were the dominant pathogens, all detected with clinically significant high viral loads. HHV6 positive cases were significantly younger and less likely to have a positive family/personal history for FS. Influenza positives showed a higher rate of complex seizures, lower leukocyte and higher monocyte counts. AV positive cases were more likely to have a positive family history for FS and showed higher C-reactive protein values. In conclusion, a high viral load may contribute to the development of a FS in respiratory tract infections.
- Published
- 2021
- Full Text
- View/download PDF
42. Severe Pneumonia and Sepsis Caused by Dialister pneumosintes in an Adolescent.
- Author
-
Kaiser M, Weis M, Kehr K, Varnholt V, Schroten H, and Tenenbaum T
- Abstract
Background: Dialister pneumosintes ( D. pneumosintes ) is known to cause dental, periodontal or sinus infections. To date, the pathogen has only been described in a small number of cases with a severe infection., Case Report: We describe the clinical case of a 13-year-old, obese female patient that presented with acute respiratory failure and sepsis. A CT-scan showed extensive bilateral patchy areas, subpleural and peribronchovascular consolidations with surrounding ground-glass opacity, extensive consolidations in the lower lobes of both lungs matching to a severe pneumonia and clinically emerging acute respiratory distress syndrome. Moreover, it showed extensive sinusitis of the right sinus frontalis, maxillaris and right cellulae ethmoidales. D. pneumosintes was isolated from an anaerobic blood culture obtained at admission. The antibiotic treatment included piperacillin/tazobactam and oral switch to ampicillin/sulbactam plus ciprofloxacin., Conclusions: We describe the first adolescent with severe systemic D. pneumosintes infection. Since the pathogen is difficult to culture the systemic virulence remains unclear. This work aims to sensitize health care specialists to consider D. pneumosintes infection in patients with periodontal or sinusal infection.
- Published
- 2021
- Full Text
- View/download PDF
43. Emergence of Macrolide-Resistant Mycoplasma pneumoniae during an Outbreak in a Primary School: Clinical Characterization of Hospitalized Children.
- Author
-
Hubert D, Dumke R, Weichert S, Welker S, Tenenbaum T, and Schroten H
- Abstract
Mycoplasma pneumoniae ( M. pneumoniae ) is a common causative pathogen of community-acquired pneumonia. Here, we report the development of macrolide resistance during a school outbreak of severe M. pneumoniae infections in southwest Germany. We conducted a case series to assess the clinical and laboratory characteristics of hospitalized children with M. pneumonia infection and the prevalence of macrolide-resistant M. pneumoniae (MRMP) in this patient group. We retrospectively analyzed 23 children with serologically (19 patients) and/or PCR (eight patients) confirmed M. pneumoniae infection between October 2019 and December 2019. Most of the 15 hospitalized patients had lower respiratory tract infection (n = 10) and required oxygen therapy (83%). The median length of hospitalization was 7 days (range 3-10 days). In 8/15 patients (53.3%) azithromycin and in 4/15 (26.6%) clarithromycin treatment was applied. However, among the five patients for which extended molecular characterization was performed, sequencing of 23S rRNA revealed no mutation only in the first case, but development of macrolide resistance A2058G in four subsequent cases. Hence, we identified a cluster of hospitalized patients with emerging MRMP. Further studies are warranted to confirm a potential link between macrolide resistance and disease severity.
- Published
- 2021
- Full Text
- View/download PDF
44. The Choroid Plexus Is Permissive for a Preactivated Antigen-Experienced Memory B-Cell Subset in Multiple Sclerosis.
- Author
-
Haas J, Rudolph H, Costa L, Faller S, Libicher S, Würthwein C, Jarius S, Ishikawa H, Stump-Guthier C, Tenenbaum T, Schwerk C, Schroten H, and Wildemann B
- Subjects
- Adult, Cells, Cultured, Female, Humans, Male, Transendothelial and Transepithelial Migration physiology, B-Lymphocyte Subsets immunology, Blood-Brain Barrier immunology, Chemotaxis, Leukocyte immunology, Choroid Plexus immunology, Immunologic Memory immunology, Multiple Sclerosis, Relapsing-Remitting immunology
- Abstract
The role of B cells in multiple sclerosis (MS) is increasingly recognized. B cells undergo compartmentalized redistribution in blood and cerebrospinal fluid (CSF) during active MS, whereby memory B cells accumulate in the CSF. While B-cell trafficking across the blood-brain barrier has been intensely investigated, cellular diapedesis through the blood-CSF barrier (BCSFB) is incompletely understood. To investigate how B cells interact with the choroid plexus to transmigrate into the CSF we isolated circulating B cells from healthy donors (HC) and MS patients, utilized an inverted cell culture filter system of human choroid plexus papilloma (HIBCPP) cells to determine transmigration rates of B-cell subsets, immunofluorescence, and electron microscopy to analyze migration routes, and qRT-PCR to determine cytokines/chemokines mediating B-cell diapedesis. We also screened the transcriptome of intrathecal B cells from MS patients. We found, that spontaneous transmigration of HC- and MS-derived B cells was scant, yet increased significantly in response to B-cell specific chemokines CXCL-12/CXCL-13, was further boosted upon pre-activation and occurred via paracellular and transcellular pathways. Migrating cells exhibited upregulation of several genes involved in B-cell activation/migration and enhanced expression of chemokine receptors CXCR4/CXCR5, and were predominantly of isotype class switched memory phenotype. This antigen-experienced migratory subset displayed more pronounced chemotactic activities in MS than in HC and was retrieved in intrathecal B cells from patients with active MS. Trafficking of class-switched memory B cells was downscaled in a small cohort of natalizumab-exposed MS patients and the proportions of these phenotypes were reduced in peripheral blood yet were enriched intrathecally in patients who experienced recurrence of disease activity after withdrawal of natalizumab. Our findings highlight the relevance of the BCSFB as important gate for the entry of potentially harmful activated B cells into the CSF., Competing Interests: BW has received research grants and/or honoria from Alexion, Merck Serono, Biogen, Teva, Novartis, Sanofi Genzyme, Bayer Healthcare, and research grants from the Dietmar Hopp Foundation, the Klaus Tschira Foundation and the Deutsche Forschungsgemeinschaft (DFG). The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2021 Haas, Rudolph, Costa, Faller, Libicher, Würthwein, Jarius, Ishikawa, Stump-Guthier, Tenenbaum, Schwerk, Schroten and Wildemann.)
- Published
- 2021
- Full Text
- View/download PDF
45. Echovirus-30 Infection Alters Host Proteins in Lipid Rafts at the Cerebrospinal Fluid Barrier In Vitro.
- Author
-
Wiatr M, Staubach S, Figueiredo R, Stump-Guthier C, Ishikawa H, Schwerk C, Schroten H, Hanisch FG, Rudolph H, and Tenenbaum T
- Abstract
Echovirus-30 (E-30) is a non-polio enterovirus responsible for meningitis outbreaks in children worldwide. To gain access to the central nervous system (CNS), E-30 first has to cross the blood-brain barrier (BBB) or the blood-cerebrospinal fluid barrier (BCSFB). E-30 may use lipid rafts of the host cells to interact with and to invade the BCSFB. To study enteroviral infection of the BCSFB, an established in vitro model based on human immortalized brain choroid plexus papilloma (HIBCPP) cells has been used. Here, we investigated the impact of E-30 infection on the protein content of the lipid rafts at the BCSFB in vitro. Mass spectrometry analysis following E-30 infection versus uninfected conditions revealed differential abundancy in proteins implicated in cellular adhesion, cytoskeleton remodeling, and endocytosis/vesicle budding. Further, we evaluated the blocking of endocytosis via clathrin/dynamin blocking and its consequences for E-30 induced barrier disruption. Interestingly, blocking of endocytosis had no impact on the capacity of E-30 to induce loss of barrier properties in HIBCPP cells. Altogether, these data highlight the impact of E-30 on HIBCPP cells microdomain as an important factor for host cell alteration.
- Published
- 2020
- Full Text
- View/download PDF
46. Polar Infection of Echovirus-30 Causes Differential Barrier Affection and Gene Regulation at the Blood-Cerebrospinal Fluid Barrier.
- Author
-
Wiatr M, Figueiredo R, Stump-Guthier C, Winter P, Ishikawa H, Adams O, Schwerk C, Schroten H, Rudolph H, and Tenenbaum T
- Subjects
- Adult, Blood-Brain Barrier metabolism, Cell Polarity, Cell Survival, Choroid Plexus cytology, Choroid Plexus metabolism, Choroid Plexus pathology, Electric Impedance, Female, Gene Expression Regulation, High-Throughput Nucleotide Sequencing, Humans, Models, Biological, Tumor Cells, Cultured, Blood-Brain Barrier virology, Choroid Plexus virology, Enterovirus B, Human pathogenicity, Gene Regulatory Networks
- Abstract
Echovirus-30 (E-30) is responsible for the extensive global outbreaks of meningitis in children. To gain access to the central nervous system, E-30 first has to cross the epithelial blood-cerebrospinal fluid barrier. Several meningitis causing bacteria preferentially infect human choroid plexus papilloma (HIBCPP) cells in a polar fashion from the basolateral cell side. Here, we investigated the polar infection of HIBCPP cells with E-30. Both apical and basolateral infections caused a significant decrease in the transepithelial electrical resistance of HIBCPP cells. However, to reach the same impact on the barrier properties, the multiplicity of infection of the apical side had to be higher than that of the basolateral infection. Furthermore, the number of infected cells at respective time-points after basolateral infection was significantly higher compared to apical infection. Cytotoxic effects of E-30 on HIBCPP cells during basolateral infection were observed following prolonged infection and appeared more drastically compared to the apical infection. Gene expression profiles determined by massive analysis of cDNA ends revealed distinct regulation of specific genes depending on the side of HIBCPP cells' infection. Altogether, our data highlights the polar effects of E-30 infection in a human in vitro model of the blood-cerebrospinal fluid barrier leading to central nervous system inflammation.
- Published
- 2020
- Full Text
- View/download PDF
47. Antibiotic utilization in hospitalized children under 2 years of age with influenza or respiratory syncytial virus infection - a comparative, retrospective analysis.
- Author
-
Papan C, Willersinn M, Weiß C, Karremann M, Schroten H, and Tenenbaum T
- Subjects
- C-Reactive Protein analysis, Coinfection diagnosis, Female, Humans, Hyperbaric Oxygenation, Infant, Influenza, Human drug therapy, Influenza, Human virology, Length of Stay, Logistic Models, Male, Odds Ratio, Respiratory Syncytial Virus Infections drug therapy, Respiratory Syncytial Virus Infections virology, Retrospective Studies, Risk Factors, Anti-Bacterial Agents therapeutic use, Influenza, Human diagnosis, Respiratory Syncytial Virus Infections diagnosis
- Abstract
Background: Infections due to Respiratory Syncytial Virus (RSV) and Influenza virus (FLU) are leading causes of hospitalization in young children. Yet, there is little data on factors associated with antibiotic use in these patients., Methods: We conducted a retrospective, single-center study of all patients below 2 years of age hospitalized between 2014 and 2018. We compared children with RSV infection to children with FLU infection analyzing clinical characteristics and factors contributing to an increased rate of antimicrobial utilization., Results: RSV infection was diagnosed in 476/573 (83.1%), FLU in 95/573 (16.6%), and RSV-FLU-co-infection in 2/573 (0.3%) patients. Median age was lower for RSV compared to FLU (4 vs. 12 months; p < 0.0001). Children with RSV had longer hospitalization (5 vs. 4 days; p = 0.0023) and needed oxygen more frequently (314/476 vs. 23/95; p < 0.0001) than FLU patients. There was no significant difference in the overall antibiotic utilization between RSV and FLU patients (136/476 vs. 21/95; p = 0.2107). Logistic regression analyses revealed that septic appearance on admission (odds ratio [OR] 8.95, 95% confidence interval [CI] 1.5-54.1), acute otitis media (OR 4.5, 95% CI 2.1-9.4), a longer oxygen therapy (OR 1.40; 95% CI 1.13-1.74) and a higher C-reactive protein (CRP) (OR 1.7, 95% CI 1.5-2.0) were significantly associated with antibiotic use in both groups, but not age or pneumonia., Conclusions: In our cohort, the rate of antibiotic utilization was comparable between RSV and FLU patients, while for both groups distinct clinical presentation and a high CRP value were associated with higher antibiotic use.
- Published
- 2020
- Full Text
- View/download PDF
48. Human CD4 + T cell subsets differ in their abilities to cross endothelial and epithelial brain barriers in vitro.
- Author
-
Nishihara H, Soldati S, Mossu A, Rosito M, Rudolph H, Muller WA, Latorre D, Sallusto F, Sospedra M, Martin R, Ishikawa H, Tenenbaum T, Schroten H, Gosselet F, and Engelhardt B
- Subjects
- Biological Transport immunology, Cell Movement immunology, Central Nervous System immunology, Choroid Plexus immunology, Choroid Plexus physiology, Endothelial Cells cytology, Humans, Blood-Brain Barrier immunology, CD4-Positive T-Lymphocytes cytology, Epithelial Cells cytology, T-Lymphocyte Subsets cytology
- Abstract
Background: The brain barriers establish compartments in the central nervous system (CNS) that significantly differ in their communication with the peripheral immune system. In this function they strictly control T-cell entry into the CNS. T cells can reach the CNS by either crossing the endothelial blood-brain barrier (BBB) or the epithelial blood-cerebrospinal fluid barrier (BCSFB) of the choroid plexus (ChP)., Objective: Analysis of the cellular and molecular mechanisms involved in the migration of different human CD4
+ T-cell subsets across the BBB versus the BCSFB., Methods: Human in vitro models of the BBB and BCSFB were employed to study the migration of circulating and CNS-entry experienced CD4+ T helper cell subsets (Th1, Th1*, Th2, Th17) across the BBB and BCSFB under inflammatory and non-inflammatory conditions in vitro., Results: While under non-inflammatory conditions Th1* and Th1 cells preferentially crossed the BBB, under inflammatory conditions the migration rate of all Th subsets across the BBB was comparable. The migration of all Th subsets across the BCSFB from the same donor was 10- to 20-fold lower when compared to their migration across the BBB. Interestingly, Th17 cells preferentially crossed the BCSFB under both, non-inflamed and inflamed conditions. Barrier-crossing experienced Th cells sorted from CSF of MS patients showed migratory characteristics indistinguishable from those of circulating Th cells of healthy donors. All Th cell subsets could additionally cross the BCSFB from the CSF to ChP stroma side. T-cell migration across the BCSFB involved epithelial ICAM-1 irrespective of the direction of migration., Conclusions: Our observations underscore that different Th subsets may use different anatomical routes to enter the CNS during immune surveillance versus neuroinflammation with the BCSFB establishing a tighter barrier for T-cell entry into the CNS compared to the BBB. In addition, CNS-entry experienced Th cell subsets isolated from the CSF of MS patients do not show an increased ability to cross the brain barriers when compared to circulating Th cell subsets from healthy donors underscoring the active role of the brain barriers in controlling T-cell entry into the CNS. Also we identify ICAM-1 to mediate T cell migration across the BCSFB.- Published
- 2020
- Full Text
- View/download PDF
49. Distinct migratory pattern of naive and effector T cells through the blood-CSF barrier following Echovirus 30 infection.
- Author
-
Wiatr M, Stump-Guthier C, Latorre D, Uhlig S, Weiss C, Ilonen J, Engelhardt B, Ishikawa H, Schwerk C, Schroten H, Tenenbaum T, and Rudolph H
- Subjects
- Blood-Brain Barrier metabolism, Blood-Brain Barrier virology, Humans, T-Lymphocytes metabolism, Tumor Cells, Cultured, Cell Movement immunology, Choroid Plexus metabolism, Choroid Plexus virology, Echovirus Infections immunology, T-Lymphocytes immunology
- Abstract
Background: Echovirus 30 (E-30) is one of the most frequently isolated pathogens in aseptic meningitis worldwide. To gain access to the central nervous system (CNS), E-30 and immune cells have to cross one of the two main barriers of the CNS, the epithelial blood-cerebrospinal fluid barrier (BCSFB) or the endothelial blood-brain barrier (BBB). In an in vitro model of the BCSFB, it has been shown that E-30 can infect human immortalized brain choroid plexus papilloma (HIBCPP) cells., Methods: In this study we investigated the migration of different T cell subpopulations, naive and effector T cells, through HIBCPP cells during E-30 infection. Effects of E-30 infection and the migration process were evaluated via immunofluorescence and flow cytometry analysis, as well as transepithelial resistance and dextran flux measurement., Results: Th1 effector cells and enterovirus-specific effector T cells migrated through HIBCPP cells more efficiently than naive CD4
+ T cells following E-30 infection of HIBCPP cells. Among the different naive T cell populations, CD8+ T cells crossed the E-30-infected HIBCPP cell layer in a significantly higher number than CD4+ T cells. A large amount of effector T cells also remained attached to the basolateral side of the HIBCPP cells compared with naive T cells. Analysis of HIBCPP barrier function showed significant alteration after E-30 infection and trans- as well as paracellular migration of T cells independent of the respective subpopulation. Morphologic analysis of migrating T cells revealed that a polarized phenotype was induced by the chemokine CXCL12, but reversed to a round phenotype after E-30 infection. Further characterization of migrating Th1 effector cells revealed a downregulation of surface adhesion proteins such as LFA-1 PSGL-1, CD44, and CD49d., Conclusion: Taken together these results suggest that naive CD8+ and Th1 effector cells are highly efficient to migrate through the BCSFB in an inflammatory environment. The T cell phenotype is modified during the migration process through HIBCPP cells.- Published
- 2019
- Full Text
- View/download PDF
50. Strain-dependent effects of clinical echovirus 30 outbreak isolates at the blood-CSF barrier.
- Author
-
Dahm T, Adams O, Boettcher S, Diedrich S, Morozov V, Hansman G, Fallier-Becker P, Schädler S, Burkhardt CJ, Weiss C, Stump-Guthier C, Ishikawa H, Schroten H, Schwerk C, Tenenbaum T, and Rudolph H
- Subjects
- Blood-Brain Barrier metabolism, Blood-Brain Barrier ultrastructure, Cell Line, Tumor, Cell Survival physiology, Cells, Cultured, Cerebrospinal Fluid metabolism, Choroid Plexus metabolism, Choroid Plexus ultrastructure, Enterovirus B, Human metabolism, Humans, Phylogeny, Species Specificity, Blood-Brain Barrier virology, Cerebrospinal Fluid virology, Choroid Plexus virology, Disease Outbreaks, Enterovirus B, Human isolation & purification
- Abstract
Background: Echovirus (E) 30 (E-30) meningitis is characterized by neuroinflammation involving immune cell pleocytosis at the protective barriers of the central nervous system (CNS). In this context, infection of the blood-cerebrospinal fluid barrier (BCSFB), which has been demonstrated to be involved in enteroviral CNS pathogenesis, may affect the tight junction (TJ) and adherens junction (AJ) function and morphology., Methods: We used an in vitro human choroid plexus epithelial (HIBCPP) cell model to investigate the effect of three clinical outbreak strains (13-311, 13-759, and 14-397) isolated in Germany in 2013, and compared them to E-30 Bastianni. Conducting transepithelial electrical resistance (TEER), paracellular dextran flux measurement, quantitative real-time polymerase chain reaction (qPCR), western blot, and immunofluorescence analysis, we investigated TJ and AJ function and morphology as well as strain-specific E-30 infection patterns. Additionally, transmission electron and focused ion beam microscopy electron microscopy (FIB-SEM) was used to evaluate the mode of leukocyte transmigration. Genome sequencing and phylogenetic analyses were performed to discriminate potential genetic differences among the outbreak strains., Results: We observed a significant strain-dependent decrease in TEER with strains E-30 Bastianni and 13-311, whereas paracellular dextran flux was only affected by E-30 Bastianni. Despite strong similarities among the outbreak strains in replication characteristics and particle distribution, strain 13-311 was the only outbreak isolate revealing comparable disruptive effects on TJ (Zonula Occludens (ZO) 1 and occludin) and AJ (E-cadherin) morphology to E-30 Bastianni. Notwithstanding significant junctional alterations upon E-30 infection, we observed both para- and transcellular leukocyte migration across HIBCPP cells. Complete genome sequencing revealed differences between the strains analyzed, but no explicit correlation with the observed strain-dependent effects on HIBCPP cells was possible., Conclusion: The findings revealed distinct E-30 strain-specific effects on barrier integrity and junctional morphology. Despite E-30-induced barrier alterations leukocyte trafficking did not exclusively occur via the paracellular route.
- Published
- 2018
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.