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2. Prevalence of uveitis in syphilis patients in Taiwan

Author

Chen, Chia-Yun, primary, Kuo, Hou-Ting, additional, Hsu, Alan Y., additional, Lin, Chun-Ju, additional, Hsia, Ning-Yi, additional, Tien, Peng-Tai, additional, Lai, Chun-Ting, additional, Chen, Huan-Sheng, additional, and Tsai, Yi-Yu, additional

Published
2023
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6. Optical Coherence Tomography Biomarkers in Predicting Treatment Outcomes of Diabetic Macular Edema after Ranibizumab Injections

Author

Chang, Yen-Chieh, primary, Huang, Yu-Te, additional, Hsu, Alan Y., additional, Meng, Ping-Ping, additional, Lin, Chun-Ju, additional, Lai, Chun-Ting, additional, Hsia, Ning-Yi, additional, Chen, Huan-Sheng, additional, Tien, Peng-Tai, additional, Lin, Jane-Ming, additional, Chen, Wen-Lu, additional, and Tsai, Yi-Yu, additional

Published
2023
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9. Tinnitus as a Potential Risk Factor for Uveitis: A 14-Year Nationwide Population-Based Cohort Study in Taiwan

Author

Chen, Yi-Jye, Hsu, Alan Y., Lin, Chun-Ju, Hsia, Ning-Yi, Meng, Ping-Ping, Liao, Pei-Lun, Hsu, Min-Yen, Tien, Peng-Tai, Lai, Chun-Ting, Chen, Huan-Sheng, Chiang, Chun-Chi, and Tsai, Yi-Yu

Abstract

Tinnitus and uveitis have shared commonality in pathophysiology in terms of autoimmunity. However, no studies that have linked any association between the conditions of tinnitus and uveitis. This is a retrospective study conducted from the Taiwan National Health Insurance database in order to investigate whether tinnitus patients are at increased risk of uveitis. Patients newly diagnosed with tinnitus between 2001 and 2014 were recruited and followed up until 2018. The endpoint of interest was a diagnosis of uveitis. A total of 31,034 tinnitus patients and 124,136 matched comparisons were analyzed. Tinnitus patients were found to have a significantly higher cumulative incidence for uveitis than those without the diagnosis of tinnitus with incidence rate of 1.68 (95% CI 1.55–1.82) per 10 000 person-months for tinnitus group and 1.48 (95% CI 1.42–1.54) per 10 000 person-months for non-tinnitus group. Tinnitus patients were found to have increased risk of developing uveitis.

Published
2023
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10. Short-Term Effects of Brolucizumab in the Treatment of Wet Age-Related Macular Degeneration or Polypoidal Choroidopathy Refractory to Previous Anti-Vascular Endothelial Growth Factor Therapy

Author

Hsu, Alan Y., primary, Lin, Chih-Ying, additional, Lin, Chun-Ju, additional, Lai, Chun-Ting, additional, Hsia, Ning-Yi, additional, Lin, Jane-Ming, additional, Tien, Peng-Tai, additional, Meng, Ping-Ping, additional, Ku, Wei-Ning, additional, Chen, Wen-Lu, additional, and Tsai, Yi-Yu, additional

Published
2022
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13. Changes of Estimated Glomerular Filtration Rate and Glycated Hemoglobin A1c in Diabetic Macular Edema Patients Treated by Ranibizumab and Aflibercept in the Tertiary Referral Hospital

Author

Ku, Wei-Ning, primary, Tien, Peng-Tai, additional, Lin, Chun-Ju, additional, Chiang, Chun-Chi, additional, Hsia, Ning-Yi, additional, Lai, Chun-Ting, additional, Muo, Chih-Hsin, additional, Bair, Henry, additional, Chen, Huan-Sheng, additional, Lin, Jane-Ming, additional, Chen, Wen-Lu, additional, and Tsai, Yi-Yu, additional

Published
2022
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14. Optical Coherence Tomography Biomarkers in Predicting Treatment Outcomes of Diabetic Macular Edema After Dexamethasone Implants

Author

Huang, Yu-Te, primary, Chang, Yen-Chieh, additional, Meng, Ping-Ping, additional, Lin, Chun-Ju, additional, Lai, Chun-Ting, additional, Hsia, Ning-Yi, additional, Chen, Huan-Sheng, additional, Tien, Peng-Tai, additional, Bair, Henry, additional, Lin, Jane-Ming, additional, Chen, Wen-Lu, additional, and Tsai, Yi-Yu, additional

Published
2022
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16. Comparison of Choroidal Thickness, Foveal Avascular Zone, and Macular Capillary Density in Macular Edema Secondary to Branch Retinal Vein Occlusion Treated with Ranibizumab or Aflibercept—A Prospective Study

Author

Huang, Yu-Te, primary, Wang, I, additional, Lin, Chun-Ju, additional, Lai, Chun-Ting, additional, Hsia, Ning-Yi, additional, Chen, Huan-Sheng, additional, Tien, Peng-Tai, additional, Bair, Henry, additional, Lin, Jane-Ming, additional, Chen, Wen-Lu, additional, Chen, Chang-He, additional, Wu, Wen-Chuan, additional, and Tsai, Yi-Yu, additional

Published
2022
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17. The incidence of uveitis after systemic lymphoma in Taiwan

Author

Huang, Yu-Te, primary, Lin, Chun-Ju, additional, Liao, Pei-Lun, additional, Hsu, Min-Yen, additional, Chang, Cheng-Hsien, additional, Tien, Peng-Tai, additional, Lai, Chun-Ting, additional, Hsia, Ning-Yi, additional, Bair, Henry, additional, Chen, Huan-Sheng, additional, Chiang, Chun-Chi, additional, and Tsai, Yi-Yu, additional

Published
2022
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21. Astigmatism Management with Astigmatism-Correcting Intraocular Lens Using Two Toric Calculators – A Comparative Case Series

Author

Huang, Yu-Te, primary, Lin, Chun-Ju, additional, Lai, Chun-Ting, additional, Hsia, Ning-Yi, additional, Tien, Peng-Tai, additional, Bair, Henry, additional, Chen, Huan-Sheng, additional, Chiang, Chun-Chi, additional, Lin, Jane-Ming, additional, Chen, Wen-Lu, additional, Wu, Wen-Chuan, additional, and Tsai, Yi-Yu, additional

Published
2021
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24. Short-Term Outcomes of Refractory Diabetic Macular Edema Switch From Ranibizumab to Dexamethasone Implant and the Influential Factors: A Retrospective Real World Experience

Author

Hsia, Ning-Yi, primary, Lin, Chun-Ju, additional, Chen, Huan-Sheng, additional, Chang, Cheng-Hsien, additional, Bair, Henry, additional, Lai, Chun-Ting, additional, Lin, Jane-Ming, additional, Chen, Wen-Lu, additional, Tien, Peng-Tai, additional, Wu, Wen-Chuan, additional, and Tsai, Yi-Yu, additional

Published
2021
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26. Preoperative Vision, Gender, and Operation Time Predict Visual Improvement After Epiretinal Membrane Vitrectomy: A Retrospective Study

Author

Bair, Henry, primary, Kung, Wei-Hsun, additional, Lai, Chun-Ting, additional, Lin, Chun-Ju, additional, Chen, Huan-Sheng, additional, Chang, Cheng-Hsien, additional, Lin, Jane-Ming, additional, Hsia, Ning-Yi, additional, Chen, Wen-Lu, additional, Tien, Peng-Tai, additional, Wu, Wen-Chuan, additional, and Tsai, Yi-Yu, additional

Published
2021
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31. Endoscopy-assisted extraction of orbital and nasal foreign body.

Author

Huang, Yu-Te, Kung, Wei-Hsun, Chang, Cheng-Hsien, Ku, Wei-Ning, Tien, Peng-Tai, Chiang, Chun-Chi, and Tsai, Yi-Yu

Abstract

Penetrating orbital injury with a foreign body is a complex problem that requires an interdisciplinary therapeutic approach. Conventionally, an external approach using either transconjuntival or transseptal entry is used by an ophthalmologist. However, there is a risk of damage to the optic nerve and orbital tissue using only the traditional approach. This study concerns a 36-year-old male who has an intra-orbital foreign body (OrbFB). Timely three-dimensional reconstruction computed tomography scan demonstrated an 8-cm-long intra-OrbFB adjacent to the optic nerve penetrating to the contralateral nasal cavity. Endoscopic inspection confirmed a chopstick fragment. Assisted by transnasal endoscopy, the chopstick penetrating from the orbit to the nasal cavity was smoothly removed. Nasal endoscopy is useful for an ophthalmologist in removing foreign body in the orbit. [ABSTRACT FROM AUTHOR]

Published
2021
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32. Endogenous endophthalmitis caused by Cryptococcus neoformans Var. Gattii mimicking choroidal tumor: From positron-emission tomography/computed tomography to histopathology

Author

Lin, Chun-Ju, Chen, Wen-Lu, Lin, Jane-Ming, Tien, Peng-Tai, and Tsai, Yi-Yu

Subjects
Positron emission tomography -- Usage, Cryptococcus -- Research, Endophthalmitis -- Care and treatment, Vitrectomy -- Usage, Health
Abstract

Byline: Chun-Ju. Lin, Wen-Lu. Chen, Jane-Ming. Lin, Peng-Tai. Tien, Yi-Yu. Tsai A 60-year-old immunocompetent female with pneumonia history about 10 years ago suffered from blurred vision overall survival for 3 [...]

Published
2017

35. Significant improvement of ocular clinical pictures of iris metastasis from small-cell lung cancer after systemic chemotherapy.

Author

Huang, Li-Ying, Hsia, Ning-Yi, Lai, Chun-Ting, Tien, Peng-Tai, Lin, Chun-Ju, Lin, Jane-Ming, Tsai, Yi-Yu, and Chen, Wen-Lu

Abstract

The uveal tract is the most common ophthalmic site of ocular metastasis from systemic tumors due to the luxurious blood flow within the choroidal tissue. However, iris metastasis from systemic cancer is uncommon, accounting for only 8% of cases of uveal metastasis. There are several methods for the treatment of iris tumor. Here, we reported a case of iris metastasis from small-cell lung cancer. The tumor shrunk after systemic treatment for lung cancer and showed no recurrence after a 4-month follow-up. [ABSTRACT FROM AUTHOR]

Published
2021
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39. Kawasaki Disease Increases the Incidence of Myopia

Author

Kung, Yung-Jen, primary, Wei, Chang-Ching, additional, Chen, Liuh An, additional, Chen, Jiin Yi, additional, Chang, Ching-Yao, additional, Lin, Chao-Jen, additional, Lim, Yun-Ping, additional, Tien, Peng-Tai, additional, Chen, Hsuan-Ju, additional, Huang, Yong-San, additional, Lin, Hui-Ju, additional, and Wan, Lei, additional

Published
2017
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40. Ultra-widefield angiography in the diagnosis and management of uveitis.

Author

Hsia, Ning-Yi, Li, You-Ling, Lin, Chun-Ju, Bair, Henry, Lai, Chun-Ting, Lin, Jane-Ming, Chen, Wen-Lu, Tien, Peng-Tai, Kuo, Chung-Yuan, and Tsai, Yi-Yu

Abstract

PURPOSE: The aim of this study is to evaluate the clinical use of ultra-widefield angiography (UWFA) in uveitis. MATERIALS AND METHODS: We showed the UWFA and traditional 55° fluorescein angiography (FA) of four cases with Eales' disease, idiopathic retinal vasculitis, aneurysms, and neuroretinitis syndrome, Behçet's disease, and idiopathic panuveitis in a tertiary medical center. Comparison of UWFA with traditional 55°FA in the diagnosis and management of uveitis and review of the literature is also presented. RESULTS: Ultra-widefield FA revealed far-peripheral vascular imaging. This information would not have been easily obtained from traditional FA. With more information of the peripheral retina, it may facilitate appropriate diagnosis and monitoring, and the management may be revised. CONCLUSION: University of Western Australia played an important role to confirm the diagnosis of uveitis and to determine the corresponding treatment. [ABSTRACT FROM AUTHOR]

Published
2018
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42. Endogenous endophthalmitis caused by Var. Gattii mimicking choroidal tumor: From positron-emission tomography/computed tomography to histopathology.

Author

Lin, Chun-Ju, Chen, Wen-Lu, Lin, Jane-Ming, Tien, Peng-Tai, and Tsai, Yi-Yu

Subjects
UVEA, BIOPSY, CRYPTOCOCCUS, DIFFERENTIAL diagnosis, EYE infections, MYCOSES, CRYPTOCOCCOSIS, UVEITIS, VITREOUS body, DIAGNOSIS, TUMORS
Abstract

A 60-year-old immunocompetent female with pneumonia history about 10 years ago suffered from blurred vision overall survival for 3 weeks. Common cold with headache and unintentional body weight loss was also noted recently. Choroidal detachment simulating choroidal tumor was observed in the temporal quadrant. The 18F-fluoro-2-deoxyglucose (FDG) positron-emission tomography/computed tomography (CT) scan showed focal, mild to moderate FDG uptake in the left lateral orbit, and an enhanced lesion was seen on the recent CT scan. The suspicious choroidal tumor became larger in a week. Phacoemulsification, vitrectomy, and retinal biopsies were performed. Histochemical study of the retinal specimens established the diagnosis of endogenous cryptococcal endophthalmitis. Vitreous culture yielded Cryptococcus neoformans var. gattii. Systemic and topical voriconazole eliminated the infection. In the literature, endogenous endophthalmitis caused by C. neoformans var. gattii has not been reported in detail. The key to successful management lies in early diagnosis. If clinical improvement could not be achieved after conventional management and imaging studies have failed to yield a definite diagnosis, retinal biopsy can be considered. [ABSTRACT FROM AUTHOR]

Published
2017
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44. Prevalence of uveitis in syphilis patients in Taiwan.

Author

Chen CY, Kuo HT, Hsu AY, Lin CJ, Hsia NY, Tien PT, Lai CT, Chen HS, and Tsai YY

Subjects
Male, Humans, Retrospective Studies, Risk Factors, Taiwan epidemiology, Prevalence, Incidence, Syphilis epidemiology, Uveitis epidemiology, Uveitis diagnosis
Abstract

Few population-based studies have looked at the risk of uveitis among syphilis patients. Our study addresses the knowledge gap by reporting on uveitis risk in syphilis patients through a retrospective cohort study. The Taiwan National Health Insurance database was used for this study, covering the period from January 1st, 2009, to December 31st, 2020. We created a 1:4 propensity score matched cohort between the syphilis patients and controls, which accounted for gender, age, and comorbidities. The primary endpoint was the incidence of newly recorded uveitis. The assessment of uveitis risk in syphilis patients included the use of the Kaplan-Meier method and multivariate Cox proportional hazard model. A total of 31,597 syphilis patients and 126,379 matched comparisons were recruited. The uveitis incidence rate from our syphilis patients was 1.25 per 1000 person-years. The uveitis incidence rate from our non-syphilis group was 0.8 per 1000 person-years. After matching, the syphilis group was found to have a higher risk of developing uveitis (adjusted hazard ratio (aHR) [95% CI]: 1.57 [1.36-1.81], P  < .001). Among males and individuals aged 20-34 years, subgroup analysis showed an increased risk of uveitis in the presence of syphilis infection. The Kaplan-Meier survival curve showed a significant difference in uveitis incidence between syphilis and non-syphilis groups (log-rank test P  < .001). In summary, our study revealed that Taiwanese syphilis patients were at a higher risk of developing uveitis. These results highlight the need for regular ocular monitoring and screening in individuals with syphilis.

Published
2024
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45. Temporal and double inverted internal limiting membrane flap for bilateral choroidal ruptures complicated by bilateral macular holes.

Author

Huang LY, Lin CJ, Lai CT, Hsia NY, Bair H, Tien PT, Chen WL, Lin JM, Chiang CC, and Tsai YY

Abstract

Choroidal ruptures occur in 5% to 10% closed-globe injuries with wide variation in visual prognosis, which depending on the visual acuity at presentation, the location of the rupture, and other associated ocular injuries. We reported a case of bilateral traumatic choroidal rupture with a large macular hole. We performed surgery in the right eye of microincisional vitrectomy, temporally inverted internal limiting membrane (ILM) flap, and C3F8 tamponade; then microincisional vitrectomy, fibrotic scar removal, double inverted ILM flap, and C3F8 tamponade in the left eye. After surgery, she achieved both good anatomical and visual acuity improvement in the right eye, but limited visual acuity improvement in the left eye due to subfoveal choroidal scar formation., Competing Interests: The authors declare that there are no conflicts of interests of this paper., (Copyright: © 2022 Taiwan J Ophthalmol.)

Published
2022
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46. Significant improvement of ocular clinical pictures of iris metastasis from small-cell lung cancer after systemic chemotherapy.

Author

Huang LY, Hsia NY, Lai CT, Tien PT, Lin CJ, Lin JM, Tsai YY, and Chen WL

Abstract

The uveal tract is the most common ophthalmic site of ocular metastasis from systemic tumors due to the luxurious blood flow within the choroidal tissue. However, iris metastasis from systemic cancer is uncommon, accounting for only 8% of cases of uveal metastasis. There are several methods for the treatment of iris tumor. Here, we reported a case of iris metastasis from small-cell lung cancer. The tumor shrunk after systemic treatment for lung cancer and showed no recurrence after a 4-month follow-up., Competing Interests: The authors declare that there are no conflicts of interests of this paper., (Copyright: © 2020 Taiwan Journal of Ophthalmology.)

Published
2020
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47. Endoscopy-assisted extraction of orbital and nasal foreign body.

Author

Huang YT, Kung WH, Chang CH, Ku WN, Tien PT, Chiang CC, and Tsai YY

Abstract

Penetrating orbital injury with a foreign body is a complex problem that requires an interdisciplinary therapeutic approach. Conventionally, an external approach using either transconjuntival or transseptal entry is used by an ophthalmologist. However, there is a risk of damage to the optic nerve and orbital tissue using only the traditional approach. This study concerns a 36-year-old male who has an intra-orbital foreign body (OrbFB). Timely three-dimensional reconstruction computed tomography scan demonstrated an 8-cm-long intra-OrbFB adjacent to the optic nerve penetrating to the contralateral nasal cavity. Endoscopic inspection confirmed a chopstick fragment. Assisted by transnasal endoscopy, the chopstick penetrating from the orbit to the nasal cavity was smoothly removed. Nasal endoscopy is useful for an ophthalmologist in removing foreign body in the orbit., Competing Interests: The authors declare that there are no conflicts of interests of this paper., (Copyright: © 2020 Taiwan Journal of Ophthalmology.)

Published
2020
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