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1. Final Analysis of COVID-19 Patients With Inflammatory Bowel Disease in Japan (J-COSMOS): A Multicenter Registry Cohort Study

Author

Sasaki, Makoto, Iizuka, Masahiro, Fujiya, Mikihiro, Matsumoto, Takayuki, Kinjo, Fukunori, Nakamura, Shiro, Kamata, Noriko, Iijima, Hideki, Etani, Yuri, Ueno, Fumiaki, Hiraoka, Sakiko, Kondo, Takeo, Kagaya, Takashi, Naganuma, Makoto, Kobayashi, Kiyonori, Kobayashi, Taku, Yamamoto, Shuji, Naito, Yuji, Hisamatsu, Tadakazu, Furuta, Yoki, Mitsuyama, Keichi, Hashimoto, Yu, Arai, Katsuhiro, Kato, Shingo, Iwama, Itaru, Esaki, Motohiro, Tanaka, Hiroki, Nakase, Hiroshi, Motoya, Satoshi, Maemoto, Atsuo, Ashida, Toshifumi, Nishimata, Nobuaki, Aono, Shigeaki, Andoh, Akira, Yamamoto, Hironori, Ishihara, Shunji, Shimizu, Toshiaki, Yasuharu, Maeda, Kinoshita, Kenji, Fukuda, Katuyuki, Kato, Jun, Takeuchi, Ken, Nagahori, Masakazu, Fukuzawa, Masakatsu, Saruta, Masayuki, Suzuki, Takayoshi, Itabashi, Michio, Shinozaki, Masaru, Ishihara, Soichiro, Yoshimura, Naoki, Matsuoka, Katsuyoshi, Kakuta, Yoichi, Takahashi, Kenichi, Tominaga, Keiichi, Sakemi, Ryosuke, Nanjo, Sohachi, Yoshikawa, Shusaku, Ozeki, Keiji, Fuchigami, Ayako, Katsurada, Takehiko, Watanabe, Kenji, Sakuraba, Hirotake, Hirai, Fumihito, Hisabe, Takashi, Iwase, Shigeru, Ohmiya, Naoki, Hokari, Ryota, Nakai, Katsuhiko, Ueda, Takeshi, Abukawa, Daiki, Yamamoto, Shojiro, Koganei, Kazutaka, Kunisaki, Reiko, Hokama, Akira, Hayashi, Yuki, Yokoyama, Yoshihiro, and Matsuura, Minoru

Published
2023
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4. Risk Factors for Stoma Outlet Obstruction after Proctocolectomy for Ulcerative Colitis

Author

Ihara, Keisuke, primary, Nakamura, Takatoshi, additional, Takayanagi, Masashi, additional, Fujita, Junki, additional, Maeda, Yasunori, additional, Nishi, Yusuke, additional, Shibuya, Norisuke, additional, Hachiya, Hiroyuki, additional, Ishizuka, Mitsuru, additional, Tominaga, Keiichi, additional, Kojima, Kazuyuki, additional, and Irisawa, Atsushi, additional

Published
2024
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5. Hereditary Diffuse Gastric Cancer Treated by Prophylactic Total Gastrectomy

Author

Inaba, Yasunori, primary, Goda, Kenichi, additional, Kondo, Masayuki, additional, Abe, Keiichiro, additional, Kanamori, Akira, additional, Suzuki, Tsunehiro, additional, Tominaga, Keiichi, additional, Nakagawa, Masatoshi, additional, Morita, Shinji, additional, Kojima, Kazuyuki, additional, Ishida, Kazuyuki, additional, and Irisawa, Atsushi, additional

Published
2024
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6. Comparison of early versus late addition of granulocyte and monocyte adsorption for incomplete remission induction in ulcerative colitis.

Author

Tominaga, Keiichi, Kanazawa, Mimari, Watanabe, Shoko, Tanaka, Takanao, Kojimahara, Shunsuke, Masuyama, Satoshi, Abe, Keiichiro, Kanamori, Akira, Yamamiya, Akira, Sugaya, Takeshi, Goda, Kenichi, Fujita, Yuji, Yoshihara, Shigemi, Haruyama, Yasuo, and Irisawa, Atsushi

Subjects
REMISSION induction, ULCERATIVE colitis, CALCINEURIN
Abstract

Background and aim: Ulcerative colitis (UC) is characterized by repeated relapse and remission. Because no fundamental therapeutic strategy has been established, the treatment goal is generally to maintain the remission phase for a long period after rapid remission induction. Granulocyte and monocyte adsorption (GMA) for UC is reportedly quite safe because it does not affect immunosuppression. Moreover, it is useful in combination with other remission induction therapy. The aim of this study was to evaluate the difference in efficacy by the timing of the addition of GMA with corticosteroids, calcineurin inhibitors, and anti‐cytokine therapy for active UC. Methods: The study included 59 patients. Patients who started GMA of 5–11 days were in the early GMA combination group. Patients who started GMA 12 days or more were in the late GMA combination group. The primary endpoint was difference in the effect of additional GMA according to the timing of the intervention. The secondary endpoint was difference in the time to remission induction between the two groups. Results: Of the 32 early GMA group patients, 24 achieved remission induction. Of the 27 late group patients, 18 achieved remission induction. No significant difference in induction rates was found (P = 0.481). The early group had shorter mean time to remission induction (P < 0.001). Conclusions: In conclusion, results suggest that early addition of GMA might lead to earlier remission in patients who have had an inadequate response to remission induction therapy with corticosteroids, calcineurin inhibitors, and anti‐cytokine therapy. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Recent steroid use and the relapse risk in ulcerative colitis patients with endoscopic healing.

Author

Fukuda, Tomohiro, Yamazaki, Hajime, Miyatani, Yusuke, Sawada, Tsunaki, Shibuya, Naoki, Fukuo, Yuka, Kiyohara, Hiroki, Morikubo, Hiromu, Tominaga, Keiichi, Kakimoto, Kazuki, Imai, Takayuki, Yaguchi, Katsuki, Yamamoto, Shojiro, Ando, Katsuyoshi, Nishimata, Nobuaki, Yoshihara, Takeo, Andoh, Akira, Hibi, Toshifumi, Matsuoka, Katsuyoshi, and Sugiyama, Tomoya

Subjects
ULCERATIVE colitis, STEROID drugs, ODDS ratio, LOGISTIC regression analysis
Abstract

Summary: Background: Endoscopic healing (EH) is a therapeutic target in ulcerative colitis (UC). However, even patients who have achieved EH relapse frequently. Aims: To investigate the association between recent steroid use and relapse risk in UC patients with EH. Methods: This multi‐centre cohort study included 1212 UC patients with confirmed EH (Mayo endoscopic subscore ≤1). We excluded patients with current systemic steroid use or history of advanced therapy. We divided patients into a recent steroid group (last systemic steroid use within 1 year; n = 59) and a non‐recent or steroid‐naïve group (n = 1153). We followed the patients for 2 years to evaluate relapse, defined as induction of systemic steroids or advanced therapy. We used logistic regression to estimate the odds ratio (OR) of relapse. Results: Relapse occurred in 28.8% of the recent steroid group and 5.6% of the non‐recent/steroid‐naïve group (multi‐variable‐adjusted OR 5.53 [95% CI 2.85–10.7]). The risk of relapse decreased with time since the last steroid use: 28.8% for less than 1 year after steroid therapy, 22.9% for 1 year, 16.0% for 2 years and 7.9% beyond 3 years, approaching 4.0% in steroid‐naïve patients. (ptrend <0.001). Conclusions: Even for patients with UC who achieved EH, the risk of relapse remains high following recent steroid therapy. Physicians need to consider the duration since last steroid use to stratify the relapse risk in UC patients with EH. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Clinical and Pharmacokinetic Factors Associated With Adalimumab-Induced Mucosal Healing in Patients With Crohn’s Disease

Author

Andoh, Akira, Ashida, Toshifumi, Endo, Katsuya, Endo, Yutaka, Esaki, Motohiro, Fujita, Hiroshi, Fujiya, Mikihiro, Haruma, Ken, Hibi, Toshifumi, Hiraoka, Sakiko, Hirata, Ichiro, Hisamatsu, Tadakazu, Honda, Yutaka, Iijima, Hideki, Iizuka, Bunei, Ikeya, Kentaro, Inoue, Takuya, Inoue, Syuji, Ishida, Tetsuya, Ishiguro, Yo, Ishihara, Shyunji, Ito, Hiroaki, Iwakiri, Ryuichi, Kagaya, Takashi, Kanai, Takanori, Kashida, Hiroshi, Kato, Shingo, Kato, Jun, Katsurada, Takehiko, Kinjyo, Fukunori, Kobayashi, Kiyonori, Kodama, Mayumi, Kunisaki, Reiko, Kurahara, Koichi, Kurokami, Takafumi, Kyouwon, Lee, Matsuda, Koichiro, Matsueda, Kazuhiro, Matsui, Toshiyuki, Matsumoto, Takayuki, Mitsuyama, Keiichi, Mizokami, Yuji, Motoya, Satoshi, Naito, Yuji, Nakagawa, Tomoo, Nakamura, Shiro, Nakase, Hiroshi, Nojima, Masanori, Nomura, Masafumi, Ogawa, Atsuhiro, Okazaki, Kazuichi, Otsuka, Kazuaki, Sakuraba, Hirotake, Saruta, Masayuki, Sasaki, Makoto, Shirai, Takayuki, Suga, Tomoaki, Sugimura, Kazuhito, Sugiyama, Toshiro, Suzuki, Yasuo, Takeshima, Fuminao, Tamaki, Hiroyuki, Tanaka, Shinji, Tanida, Satoshi, Tominaga, Keiichi, Tomizawa, Taku, Watababe, Kenji, Watanabe, Mamoru, Watanabe, Kenji, Yamamoto, Syojiro, Yamashita, Masaki, Yoshida, Atsushi, Yoshimura, Naoki, and Nagahori, Masakazu

Published
2018
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9. Investigating COVID-19 Pandemic Effects on Acute Pancreatitis Development—From the Perspective of Alcohol Sales (Consumption) in a Japanese Regional Hospital

Author

Sakuma, Fumi, primary, Yamamiya, Akira, additional, Abe, Yoko, additional, Nagashima, Kazunori, additional, Minaguchi, Takahito, additional, Kashima, Ken, additional, Kunogi, Yasuhito, additional, Fukushi, Koh, additional, Inaba, Yasunori, additional, Sugaya, Takeshi, additional, Tominaga, Keiichi, additional, Goda, Kenichi, additional, and Irisawa, Atsushi, additional

Published
2023
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10. Proposal and Validation of New Diagnostic Criteria for Diagnostic Weights of Endoultrasonographic Findings for Early Chronic Pancreatitis

Author

Kashima, Ken, primary, Yamamiya, Akira, additional, Abe, Yoko, additional, Nagashima, Kazunori, additional, Minaguchi, Takahito, additional, Kunogi, Yasuhito, additional, Sakuma, Fumi, additional, Fukushi, Koh, additional, Inaba, Yasunori, additional, Sugaya, Takeshi, additional, Tominaga, Keiichi, additional, Goda, Kenichi, additional, and Irisawa, Atsushi, additional

Published
2023
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12. Risk Factors for Developing Metachronous Superficial Gastric Epithelial Neoplasms after Endoscopic Submucosal Dissection.

Author

Suzuki, Tsunehiro, Goda, Kenichi, Ishikawa, Manabu, Yamaguchi, Shintaro, Yoshinaga, Tomonori, Kondo, Masayuki, Kanazawa, Mimari, Kunogi, Yasuhito, Tanaka, Takanao, Kanamori, Akira, Abe, Keiichiro, Yamamiya, Akira, Sugaya, Takeshi, Tominaga, Keiichi, Yamagishi, Hidetsugu, Masuyama, Hironori, and Irisawa, Atsushi

Subjects
HELICOBACTER pylori infections, GASTRIC mucosa, DUODENAL tumors, HELICOBACTER pylori, TUMORS, STOMACH cancer, DISSECTION
Abstract

Background: Although endoscopic submucosal dissection (ESD) provides a high rate of curative resection, the remaining gastric mucosa after ESD is at risk for metachronous superficial gastric epithelial neoplasms (MSGENs). It leaves room for risk factors for developing MSGENs after ESD. This study aimed to identify clinicopathological risk factors for the occurrence of MSGENs, and to evaluate the association of Helicobacter pylori (H. pylori) with the MSGENs. Methods: We conducted a retrospective cohort study including 369 patients with 382 lesions that underwent ESD for adenoma/early gastric cancer. Results: Twenty-seven MSGENs occurred. The subjects were divided into MSGEN and not-MSGEN groups. There was a significantly higher frequency of histological intestinal metaplasia (HIM) and initial neoplasm location in the upper or middle parts (INUM) in the MSGEN group. The HIM and INUM groups had a significantly higher cumulative incidence of MSGENs. We compared 27 patients from the MSGEN group and 27 patients from the not-MSGEN group that were matched to the MSGEN group for variables including HIM and INUM. There was a significantly higher frequency of the spontaneous disappearance of H. pylori in the MSGEN group. Conclusions: HIM, INUM, and the spontaneous disappearance of H. pylori may be clinicopathological risk factors for developing MSGENs after ESD. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Final analysis of COVID-19 patients with inflammatory bowel disease in Japan (J-COSMOS): a multicenter registry cohort study

Author

Nakase, Hiroshi, primary, Hayashi, Yuki, additional, Yokoyama, Yoshihiro, additional, Matsumoto, Takayuki, additional, Matsuura, Minoru, additional, Iijima, Hideki, additional, Matsuoka, Katsuyoshi, additional, Ohmiya, Naoki, additional, Ishihara, Shunji, additional, Hirai, Fumihito, additional, Abukawa, Daiki, additional, Hisamatsu, Tadakazu, additional, Sasaki, Makoto, additional, Iizuka, Masahiro, additional, Fujiya, Mikihiro, additional, Kinjo, Fukunori, additional, Nakamura, Shiro, additional, Kamata, Noriko, additional, Etani, Yuri, additional, Ueno, Fumiaki, additional, Hiraoka, Sakiko, additional, Kondo, Takeo, additional, Kagaya, Takashi, additional, Naganuma, Makoto, additional, Kobayashi, Kiyonori, additional, Kobayashi, Taku, additional, Yamamoto, Shuji, additional, Naito, Yuji, additional, Furuta, Yoki, additional, Mitsuyama, Keichi, additional, Hashimoto, Yu, additional, Arai, Katsuhiro, additional, Kato, Shingo, additional, Iwama, Itaru, additional, Esaki, Motohiro, additional, Tanaka, Hiroki, additional, Nakase, Hiroshi, additional, Motoya, Satoshi, additional, Maemoto, Atsuo, additional, Ashida, Toshifumi, additional, Nishimata, Nobuaki, additional, Aono, Shigeaki, additional, Andoh, Akira, additional, Yamamoto, Hironori, additional, Shimizu, Toshiaki, additional, Yasuharu, Maeda, additional, Kinoshita, Kenji, additional, Fukuda, Katuyuki, additional, Kato, Jun, additional, Takeuchi, Ken, additional, Nagahori, Masakazu, additional, Fukuzawa, Masakatsu, additional, Saruta, Masayuki, additional, Suzuki, Takayoshi, additional, Itabashi, Michio, additional, Shinozaki, Masaru, additional, Ishihara, Soichiro, additional, Yoshimura, Naoki, additional, Kakuta, Yoichi, additional, Takahashi, Kenichi, additional, Tominaga, Keiichi, additional, Sakemi, Ryosuke, additional, Nanjo, Sohachi, additional, Yoshikawa, Shusaku, additional, Ozeki, Keiji, additional, Fuchigami, Ayako, additional, Katsurada, Takehiko, additional, Watanabe, Kenji, additional, Sakuraba, Hirotake, additional, Hisabe, Takashi, additional, Iwase, Shigeru, additional, Hokari, Ryota, additional, Nakai, Katsuhiko, additional, Ueda, Takeshi, additional, Yamamoto, Shojiro, additional, Koganei, Kazutaka, additional, Kunisaki, Reiko, additional, and Hokama, Akira, additional

Published
2023
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15. Ustekinumab as the First Biological Agent for Treatment of Crohn's Disease with Growth Failure and Arrest of Puberty: A Pediatric Case

Author

Fujita, Yuji, Tominaga, Keiichi, Tanaka, Takanao, Naganuma, Junko, Koyama, Satomi, Ishida, Kazuyuki, Yoshihara, Shigemi, Fujita, Yuji, Tominaga, Keiichi, Tanaka, Takanao, Naganuma, Junko, Koyama, Satomi, Ishida, Kazuyuki, and Yoshihara, Shigemi

Abstract

A 14-year-old boy diagnosed with Crohn's disease, complicated by growth failure, arrest of puberty, and perianal abscess, was treated with ustekinumab. We observed improvements in the endoscopic and histological gastrointestinal tract pathology, growth failure, arrest of puberty, and bone mineral density. Crohn's disease can affect both growth and the development of secondary sexual characteristics and bone mineral density; thus, treatment should be selected for both the gastrointestinal tract pathology and the aforementioned factors. Few reports have shown the effectiveness of ustekinumab as the first biological agent for the treatment of pediatric Crohn's disease. In this pediatric case with growth failure and arrest of puberty, ustekinumab as the first biological agent was both effective and safe.

Published
2023

16. White Blood Cell Counts and Future Relapse in Ulcerative Colitis under Low-Dose Thiopurine Treatment in Real-World Practice: A 3-Year Japanese Multi-Center Retrospective Cohort Study.

Author

Kiyohara, Hiroki, Yamazaki, Hajime, Moriya, Kei, Akimoto, Naohiko, Kawai, Shoichiro, Takenaka, Kento, Fukuda, Tomohiro, Tominaga, Keiichi, Umeno, Junji, Shinzaki, Shinichiro, Honzawa, Yusuke, Takagi, Tomohisa, Ichikawa, Hitoshi, Endo, Toshiyuki, Ozaki, Ryo, Andoh, Akira, Matsuoka, Katsuyoshi, Hibi, Toshifumi, and Kobayashi, Taku

Published
2024
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17. Guide Wire Selection (Straight vs. Angled) in Endoscopic Retrograde Cholangiopancreatography Using a Normal Contrast Catheter Performed by a Trainee: A Single-Center Prospective Randomized Controlled Cross-Over Study

Author

Maki, Takumi, primary, Irisawa, Atsushi, additional, Yamamiya, Akira, additional, Tominaga, Keiichi, additional, Abe, Yoko, additional, Imbe, Koh, additional, Hoshi, Koki, additional, Yamabe, Akane, additional, Igarashi, Ryo, additional, Nakajima, Yuki, additional, Sato, Kentaro, additional, and Shibukawa, Goro, additional

Published
2023
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18. A case in which the tip of a plastic stent placed to prevent recurrence of walled‐off necrosis penetrated the bile duct and formed a stent–stone complex

Author

Sakuma, Fumi, primary, Irisawa, Atsushi, additional, Noguchi, Satoaki, additional, Abe, Yoko, additional, Hoshi, Koki, additional, Yamamiya, Akira, additional, Nagashima, Kazunori, additional, Kashima, Ken, additional, Kunogi, Yasuhito, additional, Fukushi, Koh, additional, Inaba, Kohei, additional, Oike, Ken, additional, Furuki, Saori, additional, Tominaga, Keiichi, additional, and Goda, Kenichi, additional

Published
2023
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20. Advanced Endoscopy for Benign Esophageal Disease: A Review Focused on Non-Erosive Reflux Disease and Eosinophilic Esophagitis

Author

Goda, Kenichi, primary, Abe, Keiichiro, additional, Kanamori, Akira, additional, Kondo, Masayuki, additional, Kojimahara, Shunsuke, additional, Kanazawa, Mimari, additional, Tanaka, Takanao, additional, Nagashima, Kazunori, additional, Suzuki, Tsunehiro, additional, Yamamiya, Akira, additional, Hoshi, Koki, additional, Tominaga, Keiichi, additional, Majima, Yuichi, additional, Iijima, Makoto, additional, and Irisawa, Atsushi, additional

Published
2022
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21. Usefulness of Adding Maspin Staining to p53 Staining for EUS-FNA Specimens of Pancreatic Ductal Adenocarcinoma

Author

Fukushi, Koh, primary, Yamamiya, Akira, additional, Tominaga, Keiichi, additional, Abe, Yoko, additional, Hoshi, Koki, additional, Nagashima, Kazunori, additional, Kashima, Ken, additional, Kunogi, Yasuhito, additional, Sakuma, Fumi, additional, Yamagishi, Hidetsugu, additional, Ishida, Kazuyuki, additional, Haruyama, Yasuo, additional, and Irisawa, Atsushi, additional

Published
2022
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22. Diagnosing chronic pancreatitis by endoscopic ultrasound assessing the association between ultrasound and pathological findings: A narrative review

Author

Yamamiya, Akira, primary, Irisawa, Atsushi, additional, Abe, Yoko, additional, Arisaka, Takahiro, additional, Ohnishi, Toshihiko, additional, Hoshi, Koki, additional, Suzuki, Tsunehiro, additional, Nagashima, Kazunori, additional, Kashima, Ken, additional, Kunogi, Yasuhito, additional, Sakuma, Fumi, additional, Fukushi, Koh, additional, Ishikawa, Manabu, additional, Mizuguchi, Nasuka, additional, Yamaguchi, Shintaro, additional, Tominaga, Keiichi, additional, and Goda, Kenichi, additional

Published
2022
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23. Significance of measurement of serum trough level and anti‐drug antibody of adalimumab as personalised pharmacokinetics in patients with Crohnʼs disease: a subanalysis of the DIAMOND trial

Author

Nakase, H., Motoya, S., Matsumoto, T., Watanabe, K., Hisamatsu, T., Yoshimura, N., Ishida, T., Kato, S., Nakagawa, T., Esaki, M., Nagahori, M., Matsui, T., Naito, Y., Kanai, T., Suzuki, Y., Nojima, M., Watanabe, M., Hibi, T., Andoh, Akira, Ashida, Toshifumi, Endo, Katsuya, Endo, Yutaka, Esaki, Motohiro, Fujita, Hiroshi, Fujiya, Mikihiro, Haruma, Ken, Hibi, Toshifumi, Hiraoka, Sakiko, Hirata, Ichiro, Hisamatsu, Tadakazu, Honda, Yutaka, Iijima, Hideki, Iizuka, Bunei, Ikeya, Kentaro, Inoue, Takuya, Inoue, Shuji, Ishida, Tetsuya, Ishiguro, Yo, Ishihara, Shunji, Ito, Hiroaki, Iwakiri, Ryuichi, Kagaya, Takashi, Kanai, Takanori, Kashida, Hiroshi, Kato, Shingo, Kato, Jun, Katsurada, Takehiko, Kinjyo, Fukunori, Kobayashi, Kiyonori, Kodama, Mayumi, Kunisaki, Reiko, Kurahara, Koichi, Kurokami, Takafumi, Kyouwon, Lee, Matsuda, Koichiro, Matsueda, Kazuhiro, Matsui, Toshiyuki, Matsumoto, Takayuki, Mitsuyama, Keiichi, Mizokami, Yuji, Motoya, Satoshi, Naito, Yuji, Nakagawa, Tomoo, Nakamura, Shiro, Nakase, Hiroshi, Nojima, Masanori, Nomura, Masafumi, Ogawa, Atsuhiro, Okazaki, Kazuichi, Otsuka, Kazuaki, Sakuraba, Hirotake, Saruta, Masayuki, Sasaki, Makoto, Shirai, Takayuki, Suga, Tomoaki, Sugimura, Kazuhito, Sugiyama, Toshiro, Suzuki, Yasuo, Takeshima, Fuminao, Tamaki, Hiroyuki, Tanaka, Shinji, Tanida, Satoshi, Tominaga, Keiichi, Tomizawa, Taku, Watanabe, Kenji, Watanabe, Mamoru, Yamamoto, Shojiro, Yamashita, Masaki, Yoshida, Atsushi, and Yoshimura, Naoki

Published
2017
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25. The Risk of Bleeding in Small/Straight Esophageal Varices with Red Color Sign on Endoscopy: A Retrospective Analysis from the Natural Course

Author

Nagashima, Kazunori, primary, Irisawa, Atsushi, additional, Kashima, Ken, additional, Sakuma, Fumi, additional, Minaguchi, Takahito, additional, Yamamiya, Akira, additional, Yamabe, Akane, additional, Hoshi, Koki, additional, Tominaga, Keiichi, additional, Iijima, Makoto, additional, and Goda, Kenichi, additional

Published
2022
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26. A case of obstructive jaundice caused by metastasis of breast cancer to the intra/extrahepatic bile duct

Author

Suzuki, Yuka, primary, Hoshi, Koki, additional, Tominaga, Keiichi, additional, Inaba, Yasunori, additional, Yoshinaga, Tomonori, additional, Kojimahara, Shunsuke, additional, Maki, Ryuichi, additional, Nemoto, Rena, additional, Tetsuka, Yugo, additional, Kawata, Yosuke, additional, Yamamiya, Akira, additional, Sugaya, Takeshi, additional, Iso, Yukihiro, additional, Takada‐Owada, Atsuko, additional, Ishida, Kazuyuki, additional, Goda, Kenichi, additional, and Irisawa, Atsushi, additional

Published
2022
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27. Size reduction of gastric fundic gland polyposis by de‐escalation of acid‐suppressive therapy

Author

Kanamori, Akira, primary, Tominaga, Keiichi, additional, Masuyama, Hironori, additional, Ishikawa, Mutsumi, additional, Masuyama, Satoshi, additional, Kondo, Masayuki, additional, Kanazawa, Mimari, additional, Tanaka, Takanao, additional, Yamaura, Masamichi, additional, Abe, Keiichiro, additional, Watanabe, Shoko, additional, Yamamiya, Akira, additional, Abe, Yoko, additional, Goda, Kenichi, additional, and Irisawa, Atsushi, additional

Published
2022
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30. Curative resection with endoscopic submucosal dissection of early gastric cancer in Helicobacter pylori-negative Ménétrier’s disease: A case report

Author

Fukushi, Koh, primary, Goda, Kenichi, additional, Kino, Hitoshi, additional, Kondo, Masayuki, additional, Kanazawa, Mimari, additional, Kashima, Ken, additional, Kanamori, Akira, additional, Abe, Keiichiro, additional, Suzuki, Tsunehiro, additional, Tominaga, Keiichi, additional, Yamagishi, Hidetsugu, additional, and Irisawa, Atsushi, additional

Published
2022
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36. Salvage Endoscopic Submucosal Dissection for Local Recurrence of Superficial Esophageal Squamous Cell Cancer after Photodynamic Therapy

Author

Kanamori, Akira, primary, Goda, Kenichi, additional, Nakamura, Tetsuya, additional, Yamagishi, Hidetsugu, additional, Ohwada, Atsuko, additional, Abe, Keiichiro, additional, Suzuki, Tsunehiro, additional, Kondo, Masayuki, additional, Tanaka, Takanao, additional, Yamamiya, Akira, additional, Takimoto, Youichi, additional, Hoshi, Koki, additional, Arisaka, Takahiro, additional, Sugaya, Takeshi, additional, Tominaga, Keiichi, additional, Majima, Yuichi, additional, Iijima, Makoto, additional, and Irisawa, Atsushi, additional

Published
2022
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37. Whole circumferential endoscopic submucosal dissection of superficial adenocarcinoma in long-segment Barrett's esophagus: A case report

Author

Abe, Keiichiro, primary, Goda, Kenichi, additional, Kanamori, Akira, additional, Suzuki, Tsunehiro, additional, Yamamiya, Akira, additional, Takimoto, Yoichi, additional, Arisaka, Takahiro, additional, Hoshi, Koki, additional, Sugaya, Takeshi, additional, Majima, Yuichi, additional, Tominaga, Keiichi, additional, Iijima, Makoto, additional, Hirooka, Shinichi, additional, Yamagishi, Hidetsugu, additional, and Irisawa, Atsushi, additional

Published
2021
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38. Analysis of Endoscopic Evaluation Reliability for Ulcerative Colitis in Histological Remission

Author

Kanazawa, Mimari, primary, Tominaga, Keiichi, additional, Yamamiya, Akira, additional, Tanaka, Takanao, additional, Watanabe, Shoko, additional, Sugaya, Takeshi, additional, Abe, Keiichiro, additional, Kanamori, Akira, additional, Arisaka, Takahiro, additional, Hoshi, Koki, additional, Iijima, Makoto, additional, Goda, Kenichi, additional, Haruyama, Yasuo, additional, and Irisawa, Atsushi, additional

Published
2021
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39. Recent Advances in Endosonography—Elastography: Literature Review

Author

Yamamiya, Akira, primary, Irisawa, Atsushi, additional, Hoshi, Koki, additional, Yamabe, Akane, additional, Izawa, Naoya, additional, Nagashima, Kazunori, additional, Minaguchi, Takahito, additional, Yamaura, Masamichi, additional, Yoshida, Yoshitsugu, additional, Kashima, Ken, additional, Kunogi, Yasuhito, additional, Sakuma, Fumi, additional, Tominaga, Keiichi, additional, Iijima, Makoto, additional, and Goda, Kenichi, additional

Published
2021
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40. A Case of Crohn’s Disease with Cardiac Tamponade Caused by Tuberculous Pericarditis: Assessment of a Rare Phenomenon

Author

Tominaga, Keiichi, primary, Tanaka, Takanao, additional, Kanazawa, Mimari, additional, Watanabe, Shoko, additional, Nemoto, Rena, additional, Abe, Keiichiro, additional, Kanamori, Akira, additional, Yamamiya, Akira, additional, Goda, Kenichi, additional, Kushima, Yoshitomo, additional, Chibana, Kazuyuki, additional, Masawa, Taito, additional, Fukuda, Tomohiro, additional, Hibi, Toshifumi, additional, and Irisawa, Atsushi, additional

Published
2021
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41. Recent trends in the occurrence of bleeding gastric and duodenal ulcers under the Japanese evidence‐based clinical practice guideline for peptic ulcer disease

Author

Nagashima, Kazunori, Tominaga, Keiichi, Fukushi, Koh, Kanamori, Akira, Sasai, Takako, and Hiraishi, Hideyuki

Subjects
proton pump inhibitor, bleeding gastric and duodenal ulcers, antithrombotic therapy, Original Article, Original Articles, guidelines, low‐dose aspirin
Abstract

Background Gastrointestinal hemorrhage occurs frequently. We reviewed the tendency of occurrence of bleeding gastric and duodenal ulcers and their association with antithrombotic therapy before and after the widespread use of Evidence‐Based Clinical Practice Guidelines for Peptic Ulcer 2009 (1st edition), which was published to improve treatment outcomes and prevent peptic ulcers. Methods The study enrolled 1105 patients with bleeding gastric and duodenal ulcers treated at our hospital between January 2000 and March 2016. They were divided into the preguideline group (807 patients treated between January 2000 and December 2010) and the postguideline group (298 patients treated between January 2011 and March 2016). The use of medications, severity, the incidence of Helicobacter pylori infection, the presence of any underlying disease, and other factors were compared between the pre‐ and postguideline groups. Results The number of patients receiving antithrombotic therapy was slightly higher in the postguideline group without a significant difference (P = 0.50). The incidence of H. pylori infection was significantly lower in the postguideline group (P

Published
2018

42. Refractory Immune Checkpoint Inhibitor-Induced Colitis Improved by Tacrolimus: A Case Report

Author

Kunogi, Yasuhito, primary, Tominaga, Keiichi, additional, Abe, Keiichiro, additional, Kanazawa, Mimari, additional, Tanaka, Takanao, additional, Watanabe, Shoko, additional, Kondo, Masayuki, additional, Kanamori, Akira, additional, Iijima, Makoto, additional, Goda, Kenichi, additional, Nozawa, Yumi, additional, Ishida, Kazuyuki, additional, and Irisawa, Atsushi, additional

Published
2021
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44. Factors Affecting Technical Difficulty in Balloon Enteroscopy-Assisted Endoscopic Retrograde Cholangiopancreatography in Patients with Surgically Altered Anatomy

Author

Izawa, Naoya, primary, Tsuchida, Kohei, additional, Tominaga, Keiichi, additional, Fukushi, Koh, additional, Sakuma, Fumi, additional, Kashima, Ken, additional, Kunogi, Yasuhito, additional, Kanazawa, Mimari, additional, Tanaka, Takanao, additional, Nagashima, Kazunori, additional, Minaguchi, Takahito, additional, Iwasaki, Mari, additional, Yamamiya, Akira, additional, Jinnai, Hidehito, additional, Yamabe, Akane, additional, Hoshi, Koki, additional, Sugaya, Takeshi, additional, Iijima, Makoto, additional, Goda, Kenichi, additional, and Irisawa, Atsushi, additional

Published
2021
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45. Interobserver Reliability of the Endoscopic Ultrasound Criteria for the Diagnosis of Early Chronic Pancreatitis: Comparison between the 2009 and 2019 Japanese Diagnostic Criteria

Author

Yamamiya, Akira, primary, Irisawa, Atsushi, additional, Tominaga, Keiichi, additional, Tsuchida, Kohei, additional, Sugaya, Takeshi, additional, Tsunemi, Misako, additional, Hoshi, Koki, additional, Jinnai, Hidehito, additional, Yamabe, Akane, additional, Izawa, Naoya, additional, Iwasaki, Mari, additional, Takimoto, Yoichi, additional, Kanamori, Akira, additional, Nagashima, Kazunori, additional, Minaguchi, Takahito, additional, Kashima, Ken, additional, Kunogi, Yasuhito, additional, Sato, Ai, additional, Goda, Kenichi, additional, Iijima, Makoto, additional, and Haruyama, Yasuo, additional

Published
2021
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46. Lower effectiveness of intravenous steroid treatment for moderate‐to‐severe ulcerative colitis in hospitalised patients with older onset: a multicentre cohort study.

Author

Okabayashi, Shinji, Yamazaki, Hajime, Tominaga, Keiichi, Miura, Miki, Sagami, Shintaro, Matsuoka, Katsuyoshi, Yamaguchi, Yoshiharu, Noake, Toshihiro, Ozeki, Keiji, Miyazaki, Ryosuke, Kamano, Toshiaki, Fukuda, Tomohiro, Yoshioka, Kyoko, Ando, Katsuyoshi, Fukuzawa, Masakatsu, Andoh, Akira, Yamamoto, Yosuke, Hibi, Toshifumi, and Kobayashi, Taku

Subjects
ULCERATIVE colitis, COHORT analysis, DISEASE remission, VENOUS thrombosis, POISSON regression, OLDER patients, INFLAMMATORY bowel diseases, PERIPHERALLY inserted central catheters
Abstract

Summary: Background: The increasing incidence of older‐onset ulcerative colitis (UC), which has a higher risk of surgery, is a global health issue. However, data regarding intravenous steroid treatment, one of the important treatment options to avoid surgery, for older‐onset UC is lacking. Aims: To evaluate the association between onset age and effectiveness of intravenous steroids in UC. Methods: This retrospective multicentre (27 facilities) cohort study included moderate‐to‐severe hospitalised UC patients who underwent their first intravenous steroids between April 2014 and July 2019. The primary outcome was clinical remission at day 30, using two‐item patient‐reported outcome scoring. The key secondary outcomes were risks of surgery and adverse events (death, infection and venous thrombosis) within 90 days. A modified Poisson regression model was used for analysis. Results: Overall, 467 UC patients (384 younger‐onset and 83 older‐onset) were enrolled. Clinical remission at day 30 was observed in 252 (65.6%) among younger‐onset patients and 43 (51.8%) among older‐onset patients (adjusted risk difference, −21.7% [95% CI, −36.1% to −7.2%]; adjusted risk ratio [ARR], 0.74 [95% CI, 0.59 to 0.93]). The risks of surgery and adverse events were higher in older‐onset UC (20.5% vs. 3.1%; ARR, 8.92 [95% CI, 4.13 to 19.27], 25.3% vs. 9.1%; ARR, 2.19 [95% CI, 1.22 to 3.92], respectively). Four deaths occurred, all involving older‐onset UC. The risks of infection and venous thrombosis were also higher in older‐onset UC (18.1% vs. 8.6%, 7.2% vs. 0.5%, respectively). Conclusions: Older‐onset was associated with a lower effectiveness of intravenous steroids with higher risks of surgery and adverse events in UC. [ABSTRACT FROM AUTHOR]

Published
2022
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