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1. Week 4 response predicts sustained virological response to all-oral direct-acting antiviral-based therapy in cirrhotic patients with hepatitis C virus genotype 3 infection

Author

Pineda, J.A., primary, Morano-Amado, L.E., additional, Granados, R., additional, Macías, J., additional, Téllez, F., additional, García-Deltoro, M., additional, Ríos, M.J., additional, Collado, A., additional, Delgado-Fernández, M., additional, Suárez-Santamaría, M., additional, Serrano, M., additional, Miralles-Álvarez, C., additional, Neukam, K., additional, Alados-Arboledas, J.C., additional, Albendín, H., additional, Alemán, M.R., additional, del Mar Alonso, M., additional, Asensi, V., additional, Blanco, M.J., additional, Borrallo, J., additional, Cabo, R., additional, Camacho, Á., additional, Casas, M.F., additional, Castro, Á., additional, Cucurull, J., additional, Cuéllar, S., additional, Cuenca, F., additional, de los Santos-Gil, I., additional, Dueñas, C., additional, Fernández, E., additional, Galera, C., additional, Gálvez, M.C., additional, García, D., additional, Geijo-Martínez, P., additional, Gómez, A., additional, Gómez, J.L., additional, Gutiérrez, F., additional, Hernández, J., additional, Llenas-García, J., additional, Mancebo, M., additional, Márquez, M., additional, Martín, J.M., additional, Martínez, L., additional, Martínez-Álvarez, R., additional, Martínez Madrid, O., additional, del Mar Masiá, M., additional, Merchante, N., additional, Merino, D., additional, Monje, P., additional, Nuñez, R., additional, Omar, M., additional, Ortega, E., additional, Padilla, S., additional, Robledano, C., additional, Pelazas, R., additional, Pérez, E., additional, Pérez-Camacho, I., additional, Pérez-Pérez, M., additional, Pernas, B., additional, Portu, J.J., additional, Raffo, M., additional, Real, L.M., additional, Reina, G., additional, Rivero, A., additional, Rivero-Juárez, A., additional, Romero-Palacios, A., additional, Portilla, J., additional, Rubio, P., additional, Ryan-Murua, P., additional, de la Hoya, P.S., additional, Santos, J., additional, Toyas, C., additional, Vera-Méndez, F., additional, Vergara, A., additional, Hernández, M.V., additional, and García, D.V., additional

Published
2017
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5. Week 4 response predicts sustained virological response to all-oral direct-acting antiviral-based therapy in cirrhotic patients with hepatitis C virus genotype 3 infection

Author

Alados-Arboledas, J.C., Albendín, H., Alemán, M.R., del Mar Alonso, M., Asensi, V., Blanco, M.J., Borrallo, J., Cabo, R., Camacho, Á., Casas, M.F., Castro, Á., Cucurull, J., Cuéllar, S., Cuenca, F., de los Santos-Gil, I., Dueñas, C., Fernández, E., Galera, C., Gálvez, M.C., García, D., Geijo-Martínez, P., Gómez, A., Gómez, J.L., Gutiérrez, F., Hernández, J., Llenas-García, J., Mancebo, M., Márquez, M., Martín, J.M., Martínez, L., Martínez-Álvarez, R., Martínez Madrid, O., del Mar Masiá, M., Merchante, N., Merino, D., Monje, P., Nuñez, R., Omar, M., Ortega, E., Padilla, S., Robledano, C., Pelazas, R., Pérez, E., Pérez-Camacho, I., Pérez-Pérez, M., Pernas, B., Portu, J.J., Raffo, M., Real, L.M., Reina, G., Rivero, A., Rivero-Juárez, A., Romero-Palacios, A., Portilla, J., Rubio, P., Ryan-Murua, P., de la Hoya, P.S., Santos, J., Serrano, M., Toyas, C., Vera-Méndez, F., Vergara, A., Hernández, M.V., García, D.V., Pineda, J.A., Morano-Amado, L.E., Granados, R., Macías, J., Téllez, F., García-Deltoro, M., Ríos, M.J., Collado, A., Delgado-Fernández, M., Suárez-Santamaría, M., Miralles-Álvarez, C., and Neukam, K.

Published
2017
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8. CAR Immunotherapy for the treatment of infectious diseases: a systematic review.

Author

Morte-Romea E, Pesini C, Pellejero-Sagastizábal G, Letona-Giménez S, Martínez-Lostao L, Aranda SL, Toyas C, Redrado S, Dolader-Ballesteros E, Arias M, Galvez EM, Sanz-Pamplona R, Pardo J, Paño-Pardo JR, and Ramírez-Labrada A

Subjects
Humans, Animals, T-Lymphocytes immunology, T-Lymphocytes transplantation, Immunotherapy, Adoptive methods, Receptors, Chimeric Antigen immunology, Receptors, Chimeric Antigen genetics, Communicable Diseases therapy, Communicable Diseases immunology
Abstract

Immunotherapy treatments aim to modulate the host's immune response to either mitigate it in inflammatory/autoimmune disease or enhance it against infection or cancer. Among different immunotherapies reaching clinical application during the last years, chimeric antigen receptor (CAR) immunotherapy has emerged as an effective treatment for cancer where different CAR T cells have already been approved. Yet their use against infectious diseases is an area still relatively poorly explored, albeit with tremendous potential for research and clinical application. Infectious diseases represent a global health challenge, with the escalating threat of antimicrobial resistance underscoring the need for alternative therapeutic approaches. This review aims to systematically evaluate the current applications of CAR immunotherapy in infectious diseases and discuss its potential for future applications. Notably, CAR cell therapies, initially developed for cancer treatment, are gaining recognition as potential remedies for infectious diseases. The review sheds light on significant progress in CAR T cell therapy directed at viral and opportunistic fungal infections., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Morte-Romea, Pesini, Pellejero-Sagastizábal, Letona-Giménez, Martínez-Lostao, Aranda, Toyas, Redrado, Dolader-Ballesteros, Arias, Galvez, Sanz-Pamplona, Pardo, Paño-Pardo and Ramírez-Labrada.)

Published
2024
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