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5 results on '"Tsubasa Nakano"'

1. Differentiating primary central nervous system lymphoma from glioblastoma by time-dependent diffusion using oscillating gradient

Author

Kiyohisa Kamimura, Tsubasa Nakano, Tomohito Hasegawa, Masanori Nakajo, Chihiro Yamada, Yoshiki Kamimura, Kentaro Akune, Fumitaka Ejima, Takuro Ayukawa, Hiroaki Nagano, Koji Takumi, Masatoyo Nakajo, Nayuta Higa, Hajime Yonezawa, Ryosuke Hanaya, Mari Kirishima, Akihide Tanimoto, Takashi Iwanaga, Hiroshi Imai, Thorsten Feiweier, and Takashi Yoshiura

Subjects
Diffusion, Glioblastoma, Magnetic resonance imaging, Primary central nervous system lymphoma, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Abstract Background This study aimed to elucidate the impact of effective diffusion time setting on apparent diffusion coefficient (ADC)-based differentiation between primary central nervous system lymphomas (PCNSLs) and glioblastomas (GBMs) and to investigate the usage of time-dependent diffusion magnetic resonance imaging (MRI) parameters. Methods A retrospective study was conducted involving 21 patients with PCNSLs and 66 patients with GBMs using diffusion weighted imaging (DWI) sequences with oscillating gradient spin-echo (Δeff = 7.1 ms) and conventional pulsed gradient (Δeff = 44.5 ms). In addition to ADC maps at the two diffusion times (ADC7.1 ms and ADC44.5 ms), we generated maps of the ADC changes (cADC) and the relative ADC changes (rcADC) between the two diffusion times. Regions of interest were placed on enhancing regions and non-enhancing peritumoral regions. The mean and the fifth and 95th percentile values of each parameter were compared between PCNSLs and GBMs. The area under the receiver operating characteristic curve (AUC) values were used to compare the discriminating performances among the indices. Results In enhancing regions, the mean and fifth and 95th percentile values of ADC44.5 ms and ADC7.1 ms in PCNSLs were significantly lower than those in GBMs (p = 0.02 for 95th percentile of ADC44.5 ms, p = 0.04 for ADC7.1 ms, and p

Published
2023
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2. Differentiating brain metastasis from glioblastoma by time-dependent diffusion MRI

Author

Kiyohisa Kamimura, Yoshiki Kamimura, Tsubasa Nakano, Tomohito Hasegawa, Masanori Nakajo, Chihiro Yamada, Kentaro Akune, Fumitaka Ejima, Takuro Ayukawa, Soichiro Ito, Hiroaki Nagano, Koji Takumi, Masatoyo Nakajo, Hiroyuki Uchida, Kazuhiro Tabata, Takashi Iwanaga, Hiroshi Imai, Thorsten Feiweier, and Takashi Yoshiura

Subjects
Diffusion, Glioblastoma, Magnetic resonance imaging, Neoplasm metastasis, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Abstract Background This study was designed to investigate the use of time-dependent diffusion magnetic resonance imaging (MRI) parameters in distinguishing between glioblastomas and brain metastases. Methods A retrospective study was conducted involving 65 patients with glioblastomas and 27 patients with metastases using a diffusion-weighted imaging sequence with oscillating gradient spin-echo (OGSE, 50 Hz) and a conventional pulsed gradient spin-echo (PGSE, 0 Hz) sequence. In addition to apparent diffusion coefficient (ADC) maps from two sequences (ADC50Hz and ADC0Hz), we generated maps of the ADC change (cADC): ADC50Hz − ADC0Hz and the relative ADC change (rcADC): (ADC50Hz − ADC0Hz)/ ADC0Hz × 100 (%). Results The mean and the fifth and 95th percentile values of each parameter in enhancing and peritumoral regions were compared between glioblastomas and metastases. The area under the receiver operating characteristic curve (AUC) values of the best discriminating indices were compared. In enhancing regions, none of the indices of ADC0Hz and ADC50Hz showed significant differences between metastases and glioblastomas. The mean cADC and rcADC values of metastases were significantly higher than those of glioblastomas (0.24 ± 0.12 × 10−3mm2/s vs. 0.14 ± 0.03 × 10−3mm2/s and 23.3 ± 9.4% vs. 14.0 ± 4.7%; all p

Published
2023
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3. Feasibility of iodine concentration and extracellular volume fraction measurement derived from the equilibrium phase dual-energy CT for differentiating thymic epithelial tumors

Author

Koji Takumi, Hiroaki Nagano, Tsuyoshi Myogasako, Tsubasa Nakano, Yoshihiko Fukukura, Kazuhiro Ueda, Kazuhiro Tabata, Akihide Tanimoto, and Takashi Yoshiura

Subjects
Radiology, Nuclear Medicine and imaging
Abstract

Purpose To assess the diagnostic feasibility of iodine concentration (IC) and extracellular volume (ECV) fraction measurement using the equilibrium phase dual-energy CT (DECT) for the evaluation of thymic epithelial tumors (TETs). Materials and methods This study included 33 TETs (11 low-risk thymomas, 11 high-risk thymomas, and 11 thymic carcinomas) that were assessed by pretreatment DECT. IC was measured during the equilibrium phases and ECV fraction was calculated using IC of the thymic lesion and the aorta. IC and ECV fraction were compared among TET subtypes using the Kruskal–Wallis H test and Mann–Whitney U test. Receiver-operating characteristic (ROC) curve analysis was performed to evaluate the ability of IC and ECV fraction to diagnose thymic carcinoma. Results IC during the equilibrium phase and ECV fraction differed among the three TET groups (both p p p Conclusion IC and ECV fraction measurement using DECT are helpful in diagnosing TETs. High IC during the equilibrium phase and high ECV fraction are suggestive of thymic carcinoma.

Published
2022

4. Diets and body condition of polar cod (Boreogadus saida) in the northern Bering Sea and Chukchi Sea

Author

Yoko Mitani, Yutaka Watanuki, Yasunori Sakurai, Yuka Iwahara, Jun Yamamoto, Tsubasa Nakano, Kohei Matsuno, and Bungo Nishizawa

Subjects
0106 biological sciences, Gelatinous zooplankton, 010504 meteorology & atmospheric sciences, Boreogadus saida, 010604 marine biology & hydrobiology, fungi, Biology, Plankton, biology.organism_classification, 01 natural sciences, Zooplankton, Oceanography, Arctic, Benthic zone, General Agricultural and Biological Sciences, 0105 earth and related environmental sciences, Invertebrate, Trophic level
Abstract

To understand trophic responses of polar cod Boreogadus saida (a key species in Arctic food webs) to changes in zooplankton and benthic invertebrate communities (prey), we compared its stomach contents and body condition between three regions with different environments: the northern Bering Sea (NB), southern Chukchi Sea (SC), and central Chukchi Sea (CC). Polar cod were sampled using a bottom trawl, and their potential prey species in the environment were sampled using a plankton net and a surface sediment sampler. Polar cod fed mainly on appendicularians in the NB and SC where copepods were the most abundant in the environment, while they fed on copepods, euphausiids, and gammarids in the CC where barnacle larvae were the most abundant species in plankton samples on average. The stomach fullness index of polar cod was higher in the NB and SC than CC, while their body condition index did not differ between these regions. The lower lipid content of appendicularians compared to other prey species is the most plausible explanation for this inconsistency.

Published
2015

5. Complete Genome Sequence of a Propionibacterium acnes Isolate from a Sarcoidosis Patient

Author

Tsubasa Nakano, Ichiro Nakagawa, Yoshiyuki Ohtsubo, Tetsuya Hayashi, Fumito Maruyama, Takayasu Watanabe, Ken Kurokawa, Kana Minegishi, Chihiro Aikawa, Yoshinobu Eishi, Yoshitoshi Ogura, and Asuka Furukawa

Subjects
Whole genome sequencing, biology, integumentary system, Human skin, medicine.disease, biology.organism_classification, Bioinformatics, Microbiology, Propionibacterium acnes, stomatognathic diseases, stomatognathic system, Genetics, medicine, Sarcoidosis, Prokaryotes, Molecular Biology, Gene
Abstract

Propionibacterium acnes is a human skin commensal that resides preferentially within sebaceous follicles and is the only microorganism that has been isolated from sarcoid lesions. We report the complete genome sequence of P. acnes , which was isolated from a Japanese patient with sarcoidosis.

Published
2013

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