1. [Immunonutrition, evidence and experiences]
- Author
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Cristina Tejera Pérez, Cristina Guillín Amarelle, Nazareth Rodríguez Novo, Gloria Lugo Rodríguez, Beatriz Mantiñán Gil, Regina Palmeiro Carballeira, Francisco Pita Gutiérrez, Rosa Argüeso Armesto, Ana Cantón Blanco, Manuel Antonio Botana López, María Teresa Fernández López, Virginia Muñoz Leira, Santiago Rodeiro Marta, and Miguel Ángel Martínez Olmos
- Subjects
Nutrition and Dietetics ,Medicine (miscellaneous) - Abstract
Immunonutrition is a science that encompasses aspects related to nutrition, immunity, infection, inflammation and tissue damage. Immunomodulatory formulas have shown benefits in a wide variety of clinical situations. The objective of this work was to review the available evidence in immunonutrition (IN). For this, a bibliographic search has been carried out with the keywords: immunonutrition, arginine, glutamine, nucleotides, omega-3 fatty acids, ERAS, fast-track. Clinical trials, reviews and clinical practice guidelines have been included. IN has been shown to reduce postoperative fistulae in head and neck cancer patients and in gastric and esophageal cancer patients, infectious complications and hospital stay. Other clinical situations that benefit from the use of IN are pancreatic cancer surgery, colorectal cancer surgery and major burns. More controlled, prospective, and randomized studies are necessary to confirm the potential benefits of IN in other clinical situations such as non-esophageal thoracic surgery, bladder cancer, gynecological surgery, hip fracture, liver pathology and COVID-19, among others.
- Published
- 2023