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16 results on '"Xie, Xianhua"'

4. Adaptation and possible ancient interspecies introgression in pigs identified by whole-genome sequencing

Author

Ai, Huashui, Fang, Xiaodong, Yang, Bin, Huang, Zhiyong, Chen, Hao, Mao, Likai, Zhang, Feng, Zhang, Lu, Cui, Leilei, He, Weiming, Yang, Jie, Yao, Xiaoming, Zhou, Lisheng, Han, Lijuan, Li, Jing, Sun, Silong, Xie, Xianhua, Lai, Boxian, Su, Ying, Lu, Yao, Yang, Hui, Huang, Tao, Deng, Wenjiang, Nielsen, Rasmus, Ren, Jun, and Huang, Lusheng

Subjects
Biological Sciences, Genetics, Human Genome, Acclimatization, Adaptation, Physiological, Amino Acid Sequence, Animals, China, Environment, Evolution, Molecular, Female, Gene Transfer, Horizontal, Genetics, Population, Genome, Genome-Wide Association Study, Haplotypes, Male, Molecular Sequence Data, Polymorphism, Single Nucleotide, Sequence Homology, Amino Acid, Swine, X Chromosome, Medical and Health Sciences, Developmental Biology, Agricultural biotechnology, Bioinformatics and computational biology
Abstract

Domestic pigs have evolved genetic adaptations to their local environmental conditions, such as cold and hot climates. We sequenced the genomes of 69 pigs from 15 geographically divergent locations in China and detected 41 million variants, of which 21 million were absent from the dbSNP database. In a genome-wide scan, we identified a set of loci that likely have a role in regional adaptations to high- and low-latitude environments within China. Intriguingly, we found an exceptionally large (14-Mb) region with a low recombination rate on the X chromosome that appears to have two distinct haplotypes in the high- and low-latitude populations, possibly underlying their adaptation to cold and hot environments, respectively. Surprisingly, the adaptive sweep in the high-latitude regions has acted on DNA that might have been introgressed from an extinct Sus species. Our findings provide new insights into the evolutionary history of pigs and the role of introgression in adaptation.

Published
2015

9. Effects of a high energy and low protein diet on hepatic and plasma characteristics and Cidea and Cidec mRNA expression in liver and adipose tissue of laying hens with fatty liver hemorrhagic syndrome.

Author

Peng, Gang, Huang, Enfu, Ruan, Jiming, Huang, Liumei, Liang, Haiping, Wei, Qing, Xie, Xianhua, Zeng, Qingjie, and Huang, Jianzhen

Subjects
LOW-protein diet, MESSENGER RNA, CELL death, ADIPOSE tissues, GENE expression, HEMORRHAGIC diseases
Abstract

Cidea and Cidec are two members of Cell death‐inducing DNA fragmentation factor‐alpha‐like effector family proteins, which could be involved in lipid or fat metabolism. To better understand the roles of Cidea and Cidec in fatty liver hemorrhagic syndrome (FLHS), 150 healthy 155‐day‐old Hyline Brown laying hens were randomly divided into control group (fed with basic diet) and experimental group (fed with high‐energy low‐protein [HELP] diet). Analysis of the liver by tissue sectioning and hematoxylin and eosin staining showed that the HELP diet induced micro‐vesicular steatosis in laying hens. Subsequently, based on the liver color scores and the range of lipid accumulation observed in histological examination, we classified livers with <50% vacuolization as mild FLHS and >50% as severe FLHS. The results showed that the levels of Cidea and Cidec mRNA expression were markedly elevated in the liver and adipose tissues with FLHS and the levels of Cidea and Cidec mRNA expression in the liver with severe FLHS were significantly higher than that in the liver with mild FLHS. Thus, the present study revealed that the Cidea and Cidec genes may be involved in pathways of FLHS formation. [ABSTRACT FROM AUTHOR]

Published
2019
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10. Genetic architecture of fatty acid composition in the longissimus dorsi muscle revealed by genome-wide association studies on diverse pig populations

Author

Zhang, Wanchang, primary, Zhang, Junjie, additional, Cui, Leilei, additional, Ma, Junwu, additional, Chen, Congying, additional, Ai, Huashui, additional, Xie, Xianhua, additional, Li, Lin, additional, Xiao, Shijun, additional, Huang, Lusheng, additional, Ren, Jun, additional, and Yang, Bin, additional

Published
2016
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11. Genome-wide association analyses for meat quality traits in Chinese Erhualian pigs and a Western Duroc × (Landrace × Yorkshire) commercial population

Author

Liu, Xianxian, primary, Xiong, Xinwei, additional, Yang, Jie, additional, Zhou, Lisheng, additional, Yang, Bin, additional, Ai, Huashui, additional, Ma, Huanban, additional, Xie, Xianhua, additional, Huang, Yixuan, additional, Fang, Shaoming, additional, Xiao, Shijun, additional, Ren, Jun, additional, Ma, Junwu, additional, and Huang, Lusheng, additional

Published
2015
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16. Genome-Wide Association Study of Meat Quality Traits in a White Duroc×Erhualian F2 Intercross and Chinese Sutai Pigs

Author

Ma, Junwu, primary, Yang, Jie, additional, Zhou, Lisheng, additional, Zhang, Zhiyan, additional, Ma, Huanban, additional, Xie, Xianhua, additional, Zhang, Feng, additional, Xiong, Xinwei, additional, Cui, Leilei, additional, Yang, Hui, additional, Liu, Xianxian, additional, Duan, Yanyu, additional, Xiao, Shijun, additional, Ai, Huashui, additional, Ren, Jun, additional, and Huang, Lusheng, additional

Published
2013
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