Search

Your search keyword '"Yen, J. J."' showing total 43 results
Start Over Author "Yen, J. J." Search Limiters Full Text
43 results on '"Yen, J. J."'

1. Spatial Imaging of Charge Transport in Silicon at Low Temperature

Author

Moffatt, R. A., Kurinsky, N. A., Stanford, C., Allen, J., Brink, P. L., Cabrera, B., Cherry, M., Inuslla, F., Ponce, F., Sundqvist, K., Yellin, S., Yen, J. J., and Young, B. A.

Subjects
Condensed Matter - Materials Science, Condensed Matter - Mesoscale and Nanoscale Physics
Abstract

We present direct imaging measurements of charge transport across a 1 cm$\times$ 1 cm$\times$ 4 mm crystal of high purity silicon ($\sim$20 k$\Omega$cm) at temperatures between 500 mK and and 5 K. We use these data to determine the intervalley scattering rate of electrons as a function of the electric field applied along the $\langle 111 \rangle$ crystal axis, and we present a phenomenological model of intervalley scattering that explains the constant scattering rate seen at low-voltage for cryogenic temperatures. We also demonstrate direct imaging measurements of effective hole mass anisotropy, which is strongly dependent on both temperature and electric field strength. The observed effects can be explained by a warping of the valence bands for carrier energies near the spin-orbit splitting energy in silicon., Comment: 5 Pages, 5 Figures. Submitted to Applied Physics Letters

Published
2018
Full Text
View/download PDF

2. Nuclear-recoil energy scale in CDMS II silicon dark-matter detectors

Author

Agnese, R., Anderson, A. J., Aramaki, T., Baker, W., Balakishiyeva, D., Banik, S., Barker, D., Thakur, R. Basu, Bauer, D. A., Binder, T., Borgland, A., Bowles, M. A., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Calkins, R., Cartaro, C., Cerdeno, D. G., Chagani, H., Chang, Y. -Y., Chen, Y., Cooley, J., Cornell, B., Cushman, P., Daal, M., Doughty, T., Dragowsky, E. M., Esteban, L., Fallows, S., Fascione, E., Figueroa-Feliciano, E., Fritts, M., Gerbier, G., Germond, R., Ghaith, M., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Holmgren, D., Hong, Z., Hsu, L., Huber, M. E., Iyer, V., Jardin, D., Jastram, A., Jena, C., Kelsey, M. H., Kennedy, A., Kubik, A., Kurinsky, N. A., Leder, A., Asamar, E. Lopez, Lukens, P., MacDonell, D., Mahapatra, R., Mandic, V., Mast, N., McCarthy, K. A., Miller, E. H., Mirabolfathi, N., Moffatt, R. A., Mohanty, B., Moore, D., Mendoza, J. D. Morales, Nelson, J., Oser, S. M., Page, K., Page, W. A., Partridge, R., Martinez, M. Penalver, Pepin, M., Phipps, A., Poudel, S., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Roberts, A., Rogers, H. E., Robinson, A. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Senapati, K., Serfass, B., Speller, D., Di Stefano, P. C. F., Stein, M., Street, J., Tanaka, H. A., Toback, D., Underwood, R., Villano, A. N., von Krosigk, B., Welliver, B., Wilson, J. S., Wilson, M. J., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., Zhang, X., and Zhao, X.

Subjects
Physics - Instrumentation and Detectors, Astrophysics - Instrumentation and Methods for Astrophysics, High Energy Physics - Experiment
Abstract

The Cryogenic Dark Matter Search (CDMS II) experiment aims to detect dark matter particles that elastically scatter from nuclei in semiconductor detectors. The resulting nuclear-recoil energy depositions are detected by ionization and phonon sensors. Neutrons produce a similar spectrum of low-energy nuclear recoils in such detectors, while most other backgrounds produce electron recoils. The absolute energy scale for nuclear recoils is necessary to interpret results correctly. The energy scale can be determined in CDMS II silicon detectors using neutrons incident from a broad-spectrum $^{252}$Cf source, taking advantage of a prominent resonance in the neutron elastic scattering cross section of silicon at a recoil (neutron) energy near 20 (182) keV. Results indicate that the phonon collection efficiency for nuclear recoils is $4.8^{+0.7}_{-0.9}$% lower than for electron recoils of the same energy. Comparisons of the ionization signals for nuclear recoils to those measured previously by other groups at higher electric fields indicate that the ionization collection efficiency for CDMS II silicon detectors operated at $\sim$4 V/cm is consistent with 100% for nuclear recoils below 20 keV and gradually decreases for larger energies to $\sim$75% at 100 keV. The impact of these measurements on previously published CDMS II silicon results is small., Comment: 22 pages, 17 figures, 1 table, 1 appendix

Published
2018
Full Text
View/download PDF

3. Thermal detection of single e-h pairs in a biased silicon crystal detector

Author

Romani, R. K., Brink, P. L., Cabrera, B., Cherry, M., Howarth, T., Kurinsky, N., Moffatt, R. A., Partridge, R., Ponce, F., Pyle, M., Tomada, A., Yellin, S., Yen, J. J., and Young, B. A.

Subjects
Physics - Instrumentation and Detectors
Abstract

We demonstrate that individual electron-hole pairs are resolved in a 1 cm$^2$ by 4 mm thick silicon crystal (0.93 g) operated at $\sim$35 mK. One side of the detector is patterned with two quasiparticle-trap-assisted electro-thermal-feedback transition edge sensor (QET) arrays held near ground potential. The other side contains a bias grid with 20\% coverage. Bias potentials up to $\pm$ 160 V were used in the work reported here. A fiber optic provides 650~nm (1.9 eV) photons that each produce an electron-hole ($e^{-} h^{+}$) pair in the crystal near the grid. The energy of the drifting charges is measured with a phonon sensor noise $\sigma$ $\sim$0.09 $e^{-} h^{+}$ pair. The observed charge quantization is nearly identical for $h^+$'s or $e^-$'s transported across the crystal., Comment: 4 journal pages, 5 figures

Published
2017
Full Text
View/download PDF

4. Results from the Super Cryogenic Dark Matter Search (SuperCDMS) experiment at Soudan

Author

SuperCDMS Collaboration, Agnese, R., Aramaki, T., Arnquist, I. J., Baker, W., Balakishiyeva, D., Banik, S., Barker, D., Thakur, R. Basu, Bauer, D. A., Binder, T., Bowles, M. A., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Calkins, R., Cartaro, C., Cerdeño, D. G., Chang, Y., Chen, Y., Cooley, J., Cornell, B., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Fascione, E., Figueroa-Feliciano, E., Fritts, M., Gerbier, G., Germond, R., Ghaith, M., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hong, Z., Hoppe, E. W., Hsu, L., Huber, M. E., Iyer, V., Jardin, D., Jastram, A., Jena, C., Kelsey, M. H., Kennedy, A., Kubik, A., Kurinsky, N. A., Loer, B., Asamar, E. Lopez, Lukens, P., MacDonell, D., Mahapatra, R., Mandic, V., Mast, N., Miller, E. H., Mirabolfathi, N., Mohanty, B., Mendoza, J. D. Morales, Nelson, J., Orrell, J. L., Oser, S. M., Page, K., Page, W. A., Partridge, R., Martinez, M. Penalver, Pepin, M., Phipps, A., Poudel, S., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Reynolds, T., Roberts, A., Robinson, A. E., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Senapati, K., Serfass, B., Speller, D., Stein, M., Street, J., Tanaka, H. A., Toback, D., Underwood, R., Villano, A. N., von Krosigk, B., Welliver, B., Wilson, J. S., Wilson, M. J., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., Zhang, X., and Zhao, X.

Subjects
High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract

We report the result of a blinded search for Weakly Interacting Massive Particles (WIMPs) using the majority of the SuperCDMS Soudan dataset. With an exposure of 1690 kg days, a single candidate event is observed, consistent with expected backgrounds. This analysis (combined with previous Ge results) sets an upper limit on the spin-independent WIMP--nucleon cross section of $1.4 \times 10^{-44}$ ($1.0 \times 10^{-44}$) cm$^2$ at 46 GeV/$c^2$. These results set the strongest limits for WIMP--germanium-nucleus interactions for masses $>$12 GeV/$c^2$.

Published
2017
Full Text
View/download PDF

5. Low-Mass Dark Matter Search with CDMSlite

Author

SuperCDMS Collaboration, Agnese, R., Anderson, A. J., Aralis, T., Aramaki, T., Arnquist, I. J., Baker, W., Balakishiyeva, D., Barker, D., Thakur, R. Basu, Bauer, D. A., Binder, T., Bowles, M. A., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Calkins, R., Cartaro, C., Cerdeno, D. G., Chang, Y., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fascione, E., Figueroa-Feliciano, E., Fritts, M., Gerbier, G., Ghaith, M., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hong, Z., Hoppe, E. W., Hsu, L., Huber, M. E., Iyer, V., Jardin, D., Jastram, A., Jena, C., Kelsey, M. H., Kennedy, A., Kubik, A., Kurinsky, N. A., Leder, A., Loer, B., Asamar, E. Lopez, Lukens, P., MacDonell, D., Mahapatra, R., Mandic, V., Mast, N., Miller, E. H., Mirabolfathi, N., Moffatt, R. A., Mohanty, B., Mendoza, J. D. Morales, Nelson, J., Orrell, J. L., Oser, S. M., Page, K., Page, W. A., Partridge, R., Pepin, M., Martinez, M. Penalver, Phipps, A., Poudel, S., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Reynolds, T., Roberts, A., Robinson, A. E., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Senapati, K., Serfass, B., Speller, D., Stein, M., Street, J., Tanaka, H. A., Toback, D., Underwood, R., Villano, A. N., von Krosigk, B., Welliver, B., Wilson, J. S., Wilson, M. J, Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., Zhang, X., and Zhao, X.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - Instrumentation and Methods for Astrophysics, High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

The SuperCDMS experiment is designed to directly detect weakly interacting massive particles (WIMPs) that may constitute the dark matter in our Galaxy. During its operation at the Soudan Underground Laboratory, germanium detectors were run in the CDMSlite mode to gather data sets with sensitivity specifically for WIMPs with masses ${<}$10 GeV/$c^2$. In this mode, a higher detector-bias voltage is applied to amplify the phonon signals produced by drifting charges. This paper presents studies of the experimental noise and its effect on the achievable energy threshold, which is demonstrated to be as low as 56 eV$_{\text{ee}}$ (electron equivalent energy). The detector-biasing configuration is described in detail, with analysis corrections for voltage variations to the level of a few percent. Detailed studies of the electric-field geometry, and the resulting successful development of a fiducial parameter, eliminate poorly measured events, yielding an energy resolution ranging from ${\sim}$9 eV$_{\text{ee}}$ at 0 keV to 101 eV$_{\text{ee}}$ at ${\sim}$10 eV$_{\text{ee}}$. New results are derived for astrophysical uncertainties relevant to the WIMP-search limits, specifically examining how they are affected by variations in the most probable WIMP velocity and the Galactic escape velocity. These variations become more important for WIMP masses below 10 GeV/$c^2$. Finally, new limits on spin-dependent low-mass WIMP-nucleon interactions are derived, with new parameter space excluded for WIMP masses $\lesssim$3 GeV/$c^2$, Comment: 30 Pages, 33 Figures v3 to match published version in PRD. v2 contains public release (and documentation) of the CDMSlite Run 2 data as ancillary files

Published
2017
Full Text
View/download PDF

6. Projected Sensitivity of the SuperCDMS SNOLAB experiment

Author

Agnese, R., Anderson, A. J., Aramaki, T., Arnquist, I., Baker, W., Barker, D., Thakur, R. Basu, Bauer, D. A., Borgland, A., Bowles, M. A., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Calkins, R., Cartaro, C., Cerdeño, D. G., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Figueroa-Feliciano, E., Fritts, M., Gerbier, G., Ghaith, M., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hofer, T., Holmgren, D., Hong, Z., Hoppe, E., Hsu, L., Huber, M. E., Iyer, V., Jardin, D., Jastram, A., Kelsey, M. H., Kennedy, A., Kubik, A., Kurinsky, N. A., Leder, A., Loer, B., Asamar, E. Lopez, Lukens, P., Mahapatra, R., Mandic, V., Mast, N., Mirabolfathi, N., Moffatt, R. A., Mendoza, J. D. Morales, Orrell, J. L., Oser, S. M., Page, K., Page, W. A., Partridge, R., Pepin, M., Phipps, A., Poudel, S., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Roberts, A., Robinson, A. E., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Serfass, B., Speller, D., Stein, M., Street, J., Tanaka, H. A., Toback, D., Underwood, R., Villano, A. N., von Krosigk, B., Welliver, B., Wilson, J. S., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., Zhang, X., and Zhao, X.

Subjects
Physics - Instrumentation and Detectors, Astrophysics - Cosmology and Nongalactic Astrophysics, High Energy Physics - Experiment
Abstract

SuperCDMS SNOLAB will be a next-generation experiment aimed at directly detecting low-mass (< 10 GeV/c$^2$) particles that may constitute dark matter by using cryogenic detectors of two types (HV and iZIP) and two target materials (germanium and silicon). The experiment is being designed with an initial sensitivity to nuclear recoil cross sections ~ 1 x 10$^{-43}$ cm$^2$ for a dark matter particle mass of 1 GeV/c$^2$, and with capacity to continue exploration to both smaller masses and better sensitivities. The phonon sensitivity of the HV detectors will be sufficient to detect nuclear recoils from sub-GeV dark matter. A detailed calibration of the detector response to low energy recoils will be needed to optimize running conditions of the HV detectors and to interpret their data for dark matter searches. Low-activity shielding, and the depth of SNOLAB, will reduce most backgrounds, but cosmogenically produced $^{3}$H and naturally occurring $^{32}$Si will be present in the detectors at some level. Even if these backgrounds are x10 higher than expected, the science reach of the HV detectors would be over three orders of magnitude beyond current results for a dark matter mass of 1 GeV/c$^2$. The iZIP detectors are relatively insensitive to variations in detector response and backgrounds, and will provide better sensitivity for dark matter particle masses (> 5 GeV/c$^2$). The mix of detector types (HV and iZIP), and targets (germanium and silicon), planned for the experiment, as well as flexibility in how the detectors are operated, will allow us to maximize the low-mass reach, and understand the backgrounds that the experiment will encounter. Upgrades to the experiment, perhaps with a variety of ultra-low-background cryogenic detectors, will extend dark matter sensitivity down to the "neutrino floor", where coherent scatters of solar neutrinos become a limiting background., Comment: SuperCDMS SNOLAB Projected sensitivity reach

Published
2016
Full Text
View/download PDF

7. WIMP-Search Results from the Second CDMSlite Run

Author

SuperCDMS Collaboration, Agnese, R., Anderson, A. J., Aramaki, T., Asai, M., Baker, W., Balakishiyeva, D., Barker, D., Thakur, R. Basu, Bauer, D. A., Billard, J., Borgland, A., Bowles, M. A., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Calkins, R., Cerdeno, D. G., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Figueroa-Feliciano, E., Ghaith, M., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jardin, D., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kennedy, A., Leder, A., Loer, B., Asamar, E. Lopez, Lukens, P., Mahapatra, R., Mandic, V., Mast, N., Mirabolfathi, N., Moffatt, R. A., Mendoza, J. D. Morales, Oser, S. M., Page, K., Page, W. A., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Ricci, Y., Roberts, A., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Serfass, B., Shank, B., Speller, D., Toback, D., Underwood, R., Upadhyayula, S., Villano, A. N., Welliver, B., Wilson, J. S., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., and Zhang, J.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - Instrumentation and Methods for Astrophysics, High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

The CDMS low ionization threshold experiment (CDMSlite) uses cryogenic germanium detectors operated at a relatively high bias voltage to amplify the phonon signal in the search for weakly interacting massive particles (WIMPs). Results are presented from the second CDMSlite run with an exposure of 70 kg days, which reached an energy threshold for electron recoils as low as 56 eV. A fiducialization cut reduces backgrounds below those previously reported by CDMSlite. New parameter space for the WIMP-nucleon spin-independent cross section is excluded for WIMP masses between 1.6 and 5.5 GeV/$c^2$., Comment: 6 pages, 4 figures. v2 Matches the accepted version in PRL

Published
2015
Full Text
View/download PDF

8. Imaging the Oblique Propagation of Electrons in Germanium Crystals at Low Temperature and Low Electric Field

Author

Moffatt, R. A., Cabrera, B., Corcoran, B. M., Kreikebaum, J. M., Redl, P., Shank, B., Yen, J. J., Young, B. A., Brink, P. L., Cherry, M., Tomada, A., Phipps, A., Sadoulet, B., and Sundqvist, K. M.

Subjects
Condensed Matter - Materials Science, Condensed Matter - Mesoscale and Nanoscale Physics
Abstract

Excited electrons in the conduction band of germanium collect into four energy minima, or valleys, in momentum space. These local minima have highly anisotropic mass tensors which cause the electrons to travel in directions which are oblique to an applied electric field at sub-Kelvin temperatures and low electric fields, in contrast to the more isotropic behavior of the holes. This experiment produces, for the first time, a full two-dimensional image of the oblique electron and hole propagation and the quantum transitions of electrons between valleys for electric fields oriented along the [0,0,1] direction. Charge carriers are excited with a focused laser pulse on one face of a germanium crystal and then drifted through the crystal by a uniform electric field of strength between 0.5 and 6 V/cm. The pattern of charge density arriving on the opposite face is used to reconstruct the trajectories of the carriers. Measurements of the two-dimensional pattern of charge density are compared in detail with Monte Carlo simulations developed for the Cryogenic Dark Matter Search (CDMS) to model the transport of charge carriers in high-purity germanium detectors.

Published
2015
Full Text
View/download PDF

9. Improved WIMP-search reach of the CDMS II germanium data

Author

Agnese, R., Anderson, A. J., Asai, M., Balakishiyeva, D., Barker, D., Thakur, R. Basu, Bauer, D. A., Billard, J., Borgland, A., Bowles, M. A., Brandt, D., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Calkins, R., Cerdeño, D. G., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Figueroa-Feliciano, E., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hertel, S. A., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jardin, D., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kennedy, A., Kiveni, M., Koch, K., Leder, A., Loer, B., Asamar, E. Lopez, Lukens, P., Mahapatra, R., Mandic, V., McCarthy, K. A., Mirabolfathi, N., Moffatt, R. A., Oser, S. M., Page, K., Page, W. A., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Ricci, Y., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Serfass, B., Shank, B., Speller, D., Toback, D., Upadhyayula, S., Villano, A. N., Welliver, B., Wilson, J. S., Wright, D. H., Yang, X., Yellin, S., Yen, J. J., Young, B. A., and Zhang, J.

Subjects
High Energy Physics - Experiment, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

CDMS II data from the 5-tower runs at the Soudan Underground Laboratory were reprocessed with an improved charge-pulse fitting algorithm. Two new analysis techniques to reject surface-event backgrounds were applied to the 612 kg days germanium-detector WIMP-search exposure. An extended analysis was also completed by decreasing the 10 keV analysis threshold to $\sim$5 keV, to increase sensitivity near a WIMP mass of 8 GeV/$c^2$. After unblinding, there were zero candidate events above a deposited energy of 10 keV and 6 events in the lower-threshold analysis. This yielded minimum WIMP-nucleon spin-independent scattering cross-section limits of $1.8 \times 10^{-44}$ and $1.18 \times 10 ^{-41}$ cm$^2$ at 90\% confidence for 60 and 8.6 GeV/$c^2$ WIMPs, respectively. This improves the previous CDMS II result by a factor of 2.4 (2.7) for 60 (8.6) GeV/$c^2$ WIMPs., Comment: 25 pages, 15 figures, slightly updated organization and text consistent with PRD referee process, Fig. 14 updated

Published
2015
Full Text
View/download PDF

10. Dark matter effective field theory scattering in direct detection experiments

Author

Schneck, K., Cabrera, B., Cerdeno, D. G., Mandic, V., Rogers, H. E., Agnese, R., Anderson, A. J., Asai, M., Balakishiyeva, D., Barker, D., Thakur, R. Basu, Bauer, D. A., Billard, J., Borgland, A., Brandt, D., Brink, P. L., Bunker, R., Caldwell, D. O., Calkins, R., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Figueroa-Feliciano, E., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jardin, D. M., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kennedy, A., Leder, A., Loer, B., Asamar, E. Lopez, Lukens, P., Mahapatra, R., McCarthy, K. A., Mirabolfathi, N., Moffatt, R. A., Mendoza, J. D. Morales, Oser, S. M., Page, K., Page, W. A., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Ricci, Y., Roberts, A., Saab, T., Sadoulet, B., Sander, J., Schnee, R. W., Scorza, S., Serfass, B., Shank, B., Speller, D., Toback, D., Upadhyayula, S., Villano, A. N., Welliver, B., Wilson, J. S., Wright, D. H., Yang, X., Yellin, S., Yen, J. J., Young, B. A., and Zhang, J.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics, High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract

We examine the consequences of the effective field theory (EFT) of dark matter-nucleon scattering for current and proposed direct detection experiments. Exclusion limits on EFT coupling constants computed using the optimum interval method are presented for SuperCDMS Soudan, CDMS II, and LUX, and the necessity of combining results from multiple experiments in order to determine dark matter parameters is discussed. We demonstrate that spectral differences between the standard dark matter model and a general EFT interaction can produce a bias when calculating exclusion limits and when developing signal models for likelihood and machine learning techniques. We also discuss the implications of the EFT for the next-generation (G2) direct detection experiments and point out regions of complementarity in the EFT parameter space., Comment: Newest version includes erratum

Published
2015
Full Text
View/download PDF

11. Maximum Likelihood Analysis of Low Energy CDMS II Germanium Data

Author

SuperCDMS Collaboration, Agnese, R., Anderson, A. J., Balakishiyeva, D., Thakur, R. Basu, Bauer, D. A., Billard, J., Borgland, A., Bowles, M. A., Brandt, D., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Cerdeno, D. G., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Figueroa-Feliciano, E., Fritts, M., Godfrey, G. L., Golwala, S. R., Graham, M., Hall, J., Harris, H. R., Hertel, S. A., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kennedy, A., Kiveni, M., Koch, K., Leder, A., Loer, B., Asamar, E. Lopez, Mahapatra, R., Mandic, V., Martinez, C., McCarthy, K. A., Mirabolfathi, N., Moffatt, R. A., Moore, D. C., Nelson, R. H., Oser, S. M., Page, K., Page, W. A., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Ricci, Y., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Serfass, B., Shank, B., Speller, D., Upadhyayula, S., Villano, A. N., Welliver, B., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., and Zhang, J.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - Instrumentation and Methods for Astrophysics, Physics - Instrumentation and Detectors
Abstract

We report on the results of a search for a Weakly Interacting Massive Particle (WIMP) signal in low-energy data of the Cryogenic Dark Matter Search (CDMS~II) experiment using a maximum likelihood analysis. A background model is constructed using GEANT4 to simulate the surface-event background from $^{210}$Pb decay-chain events, while using independent calibration data to model the gamma background. Fitting this background model to the data results in no statistically significant WIMP component. In addition, we perform fits using an analytic ad hoc background model proposed by Collar and Fields, who claimed to find a large excess of signal-like events in our data. We confirm the strong preference for a signal hypothesis in their analysis under these assumptions, but excesses are observed in both single- and multiple-scatter events, which implies the signal is not caused by WIMPs, but rather reflects the inadequacy of their background model., Comment: 12 pages, 12 figures, submitted to PRD

Published
2014
Full Text
View/download PDF

12. First direct limits on Lightly Ionizing Particles with electric charge less than $e/6$

Author

Agnese, R., Anderson, A. J., Balakishiyeva, D., Thakur, R. Basu, Bauer, D. A., Billard, J., Borgland, A., Bowles, M. A., Brandt, D., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Cerdeno, D. G., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Figueroa-Feliciano, E., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hertel, S. A., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kennedy, A., Kiveni, M., Koch, K., Leder, A., Loer, B., Asamar, E. Lopez, Mahapatra, R., Mandic, V., Martinez, C., McCarthy, K. A., Mirabolfathi, N., Moffatt, R. A., Moore, D. C., Nelson, H., Nelson, R. H., Ogburn, R. W., Page, K., Page, W. A., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Ricci, Y., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Serfass, B., Shank, B., Speller, D., Upadhyayula, S., Villano, A. N., Welliver, B., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., and Zhang, J.

Subjects
High Energy Physics - Experiment, Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - High Energy Astrophysical Phenomena, Physics - Instrumentation and Detectors
Abstract

While the Standard Model of particle physics does not include free particles with fractional charge, experimental searches have not ruled out their existence. We report results from the Cryogenic Dark Matter Search (CDMS II) experiment that give the first direct-detection limits for cosmogenically-produced relativistic particles with electric charge lower than $e$/6. A search for tracks in the six stacked detectors of each of two of the CDMS II towers found no candidates, thereby excluding new parameter space for particles with electric charges between $e$/6 and $e$/200., Comment: 5 pages, 6 figures, submitted to PRL

Published
2014
Full Text
View/download PDF

13. Measurement Of Quasiparticle Transport In Aluminum Films Using Tungsten Transition-Edge Sensors

Author

Yen, J. J., Shank, B., Young, B. A., Cabrera, B., Brink, P. L., Cherry, M., Kreikebaum, J. M, Moffatt, R., Redl, P., Tomada, A., and Tortorici, E. C.

Subjects
Physics - Instrumentation and Detectors
Abstract

We report new experimental studies to understand the physics of phonon sensors which utilize quasiparticle diffusion in thin aluminum films into tungsten transition-edge-sensors (TESs) operated at 35 mK. We show that basic TES physics and a simple physical model of the overlap region between the W and Al films in our devices enables us to accurately reproduce the experimentally observed pulse shapes from x-rays absorbed in the Al films. We further estimate quasiparticle loss in Al films using a simple diffusion equation approach., Comment: 5 pages, 6 figures, PRAL

Published
2014
Full Text
View/download PDF

14. Nonlinear Optimal Filter Technique For Analyzing Energy Depositions In TES Sensors Driven Into Saturation

Author

Shank, B., Yen, J. J., Cabrera, B., Kreikebaum, J. M., Moffatt, R., Redl, P., Young, B. A., Brink, P. L., Cherry, M., and Tomada, A.

Subjects
Physics - Instrumentation and Detectors, Condensed Matter - Superconductivity
Abstract

We present a detailed thermal and electrical model of superconducting transition edge sensors (TESs) connected to quasiparticle (qp) traps, such as the W TESs connected to Al qp traps used for CDMS (Cryogenic Dark Matter Search) Ge and Si detectors. We show that this improved model, together with a straightforward time-domain optimal filter, can be used to analyze pulses well into the nonlinear saturation region and reconstruct absorbed energies with optimal energy resolution., Comment: companion paper to J. J. Yen's "Measurement Of Quasiparticle Transport In Aluminum Films Using Tungsten Transition-Edge Sensors"

Published
2014

15. Search for Low-Mass WIMPs with SuperCDMS

Author

Agnese, R., Anderson, A. J., Asai, M., Balakishiyeva, D., Thakur, R. Basu, Bauer, D. A., Beaty, J., Billard, J., Borgland, A., Bowles, M. A., Brandt, D., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Cerdeno, D. G., Chagani, H., Chen, Y., Cherry, M., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., DeVaney, D., Di Stefano, P. C. F., Silva, E. Do Couto E, Doughty, T., Esteban, L., Fallows, S., Figueroa-Feliciano, E., Godfrey, G. L., Golwala, S. R., Hall, J., Hansen, S., Harris, H. R., Hertel, S. A., Hines, B. A., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kenany, S., Kennedy, A., Kiveni, M., Koch, K., Leder, A., Loer, B., Asamar, E. Lopez, Mahapatra, R., Mandic, V., Martinez, C., McCarthy, K. A., Mirabolfathi, N., Moffatt, R. A., Nelson, R. H., Novak, L., Page, K., Partridge, R., Pepin, M., Phipps, A., Platt, M., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Resch, R. W., Ricci, Y., Ruschman, M., Saab, T., Sadoulet, B., Sander, J., Schmitt, R. L., Schneck, K., Schnee, R. W., Scorza, S., Seitz, D. N., Serfass, B., Shank, B., Speller, D., Tomada, A., Upadhyayula, S., Villano, A. N., Welliver, B., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., and Zhang, J.

Subjects
High Energy Physics - Experiment, Astrophysics - Cosmology and Nongalactic Astrophysics, Physics - Instrumentation and Detectors
Abstract

We report a first search for weakly interacting massive particles (WIMPs) using the background rejection capabilities of SuperCDMS. An exposure of 577 kg-days was analyzed for WIMPs with mass < 30 GeV/c2, with the signal region blinded. Eleven events were observed after unblinding. We set an upper limit on the spin-independent WIMP-nucleon cross section of 1.2e-42 cm2 at 8 GeV/c2. This result is in tension with WIMP interpretations of recent experiments and probes new parameter space for WIMP-nucleon scattering for WIMP masses < 6 GeV/c2., Comment: 6 pages, 4 figures; figure 1 updated, submitted to Phys. Rev. Lett

Published
2014
Full Text
View/download PDF

16. CDMSlite: A Search for Low-Mass WIMPs using Voltage-Assisted Calorimetric Ionization Detection in the SuperCDMS Experiment

Author

Agnese, R., Anderson, A. J., Asai, M., Balakishiyeva, D., Thakur, R. Basu, Bauer, D. A., Billard, J., Borgland, A., Bowles, M. A., Brandt, D., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Cerdeno, D. G., Chagani, H., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Figueroa-Feliciano, E., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hertel, S. A., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kennedy, A., Kiveni, M., Koch, K., Loer, B., Asamar, E. Lopez, Mahapatra, R., Mandic, V., Martinez, C., McCarthy, K. A., Mirabolfathi, N., Moffatt, R. A., Moore, D. C., Nadeau, P., Nelson, R. H., Page, K., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Ricci, Y., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Serfass, B., Shank, B., Speller, D., Villano, A. N., Welliver, B., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., and Zhang, J.

Subjects
Physics - Instrumentation and Detectors, Astrophysics - Cosmology and Extragalactic Astrophysics, Astrophysics - Instrumentation and Methods for Astrophysics, High Energy Physics - Experiment
Abstract

SuperCDMS is an experiment designed to directly detect Weakly Interacting Massive Particles (WIMPs), a favored candidate for dark matter ubiquitous in the Universe. In this paper, we present WIMP-search results using a calorimetric technique we call CDMSlite, which relies on voltage- assisted Luke-Neganov amplification of the ionization energy deposited by particle interactions. The data were collected with a single 0.6 kg germanium detector running for 10 live days at the Soudan Underground Laboratory. A low energy threshold of 170 eVee (electron equivalent) was obtained, which allows us to constrain new WIMP-nucleon spin-independent parameter space for WIMP masses below 6 GeV/c2., Comment: 7 pages, 4 figures

Published
2013
Full Text
View/download PDF

17. Demonstration of Surface Electron Rejection with Interleaved Germanium Detectors for Dark Matter Searches

Author

Agnese, R., Anderson, A. J., Balakishiyeva, D., Thakur, R. Basu, Bauer, D. A., Borgland, A., Brandt, D., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Cerdeno, D. G., Chagani, H., Cherry, M., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., Di Stefano, P. C. F., Silva, E. Do Couto E, Doughty, T., Esteban, L., Fallows, S., Figueroa-Feliciano, E., Fox, J., Fritts, M., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hasi, J., Hertel, S. A., Hines, B. A., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kenany, S. A., Kennedy, A., Kenney, C. J., Kiveni, M., Koch, K., Loer, B., Asamar, E. Lopez, Mahapatra, R., Mandic, V., Martinez, C., McCarthy, K. A., Mirabolfathi, N., Moffatt, R. A., Moore, D. C., Nadeau, P., Nelson, R. H., Novak, L., Page, K., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Radpour, R., Rau, W., Redl, P., Reisetter, A., Resch, R. W., Ricci, Y., Saab, T., Sadoulet, B., Sander, J., Schmitt, R., Schneck, K., Schnee, R. W., Scorza, S., Seitz, D., Serfass, B., Shank, B., Speller, D., Tomada, A., Villano, A. N., Welliver, B., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., and Zhang, J.

Subjects
Physics - Instrumentation and Detectors, Astrophysics - Astrophysics of Galaxies, High Energy Physics - Experiment
Abstract

The SuperCDMS experiment in the Soudan Underground Laboratory searches for dark matter with a 9-kg array of cryogenic germanium detectors. Symmetric sensors on opposite sides measure both charge and phonons from each particle interaction, providing excellent discrimination between electron and nuclear recoils, and between surface and interior events. Surface event rejection capabilities were tested with two $^{210}$Pb sources producing $\sim$130 beta decays/hr. In $\sim$800 live hours, no events leaked into the 8--115 keV signal region, giving upper limit leakage fraction $1.7 \times 10^{-5}$ at 90% C.L., corresponding to $< 0.6$ surface event background in the future 200-kg SuperCDMS SNOLAB experiment., Comment: 5 pages, 4 figures, submitted to journal

Published
2013
Full Text
View/download PDF

18. Silicon Detector Dark Matter Results from the Final Exposure of CDMS II

Author

CDMS Collaboration, Agnese, R., Ahmed, Z., Anderson, A. J., Arrenberg, S., Balakishiyeva, D., Thakur, R. Basu, Bauer, D. A., Billard, J., Borgland, A., Brandt, D., Brink, P. L., Bruch, T., Bunker, R., Cabrera, B., Caldwell, D. O., Cerdeno, D. G., Chagani, H., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., Dejongh, F., Silva, E. Do Couto E, Doughty, T., Esteban, L., Fallows, S., Figueroa-Feliciano, E., Filippini, J., Fox, J., Fritts, M., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, R. H., Hertel, S. A., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kennedy, A., Kim, P., Kiveni, M., Koch, K., Kos, M., Leman, S. W., Loer, B., Asamar, E. Lopez, Mahapatra, R., Mandic, V., Martinez, C., McCarthy, K. A., Mirabolfathi, N., Moffatt, R. A., Moore, D. C., Nadeau, P., Nelson, R. H., Page, K., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Ricci, Y., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Serfass, B., Shank, B., Speller, D., Sundqvist, K. M., Villano, A. N., Welliver, B., Wright, D. H., Yellin, S., Yen, J. J., Yoo, J., Young, B. A., and Zhang, J.

Subjects
High Energy Physics - Experiment, Astrophysics - Cosmology and Extragalactic Astrophysics, Astrophysics - Instrumentation and Methods for Astrophysics, Physics - Instrumentation and Detectors
Abstract

We report results of a search for Weakly Interacting Massive Particles (WIMPS) with the silicon detectors of the CDMS II experiment. This blind analysis of 140.2 kg-days of data taken between July 2007 and September 2008 revealed three WIMP-candidate events with a surface-event background estimate of 0.41^{+0.20}_{-0.08}(stat.)^{+0.28}_{-0.24}(syst.). Other known backgrounds from neutrons and 206Pb are limited to < 0.13 and <0.08 events at the 90% confidence level, respectively. The exposure of this analysis is equivalent to 23.4 kg-days for a recoil energy range of 7-100 keV for a WIMP of mass 10 GeV/c2. The probability that the known backgrounds would produce three or more events in the signal region is 5.4%. A profile likelihood ratio test of the three events that includes the measured recoil energies gives a 0.19% probability for the known-background-only hypothesis when tested against the alternative WIMP+background hypothesis. The highest likelihood occurs for a WIMP mass of 8.6 GeV/c2 and WIMP-nucleon cross section of 1.9e-41 cm2., Comment: 5 pages, 4 figures, as accepted by PRL

Published
2013

19. Silicon detector results from the first five-tower run of CDMS II

Author

CDMS Collaboration, Agnese, R., Ahmed, Z., Anderson, A. J., Arrenberg, S., Balakishiyeva, D., Thakur, R. Basu, Bauer, D. A., Borgland, A., Brandt, D., Brink, P. L., Bruch, T., Bunker, R., Cabrera, B., Caldwell, D. O., Cerdeno, D. G., Chagani, H., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., Dejongh, F., Di Stefano, P. C. F., Silva, E. do Couto e, Doughty, T., Esteban, L., Fallows, S., Figueroa-Feliciano, E., Filippini, J., Fox, J., Fritts, M., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, R. H., Hertel, S. A., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kennedy, A., Kim, P., Kiveni, M., Koch, K., Kos, M., Leman, S. W., Lopez-Asamar, E., Mahapatra, R., Mandic, V., Martinez, C., McCarthy, K. A., Mirabolfathi, N., Moffatt, R. A., Moore, D. C., Nadeau, P., Nelson, R. H., Page, K., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Ricci, Y., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Serfass, B., Shank, B., Speller, D., Sundqvist, K. M., Villano, A. N., Welliver, B., Wright, D. H., Yellin, S., Yen, J. J., Yoo, J., Young, B. A., and Zhan, J.

Subjects
Astrophysics - Cosmology and Extragalactic Astrophysics, High Energy Physics - Experiment
Abstract

We report results of a search for Weakly Interacting Massive Particles (WIMPs) with the Si detectors of the CDMS II experiment. This report describes a blind analysis of the first data taken with CDMS II's full complement of detectors in 2006-2007; results from this exposure using the Ge detectors have already been presented. We observed no candidate WIMP-scattering events in an exposure of 55.9 kg-days before analysis cuts, with an expected background of ~1.1 events. The exposure of this analysis is equivalent to 10.3 kg-days over a recoil energy range of 7-100 keV for an ideal Si detector and a WIMP mass of 10 GeV/c2. These data set an upper limit of 1.7x10-41 cm2 on the WIMP-nucleon spin-independent cross section of a 10 GeV/c2 WIMP. These data exclude parameter space for spin-independent WIMP-nucleon elastic scattering that is relevant to recent searches for low-mass WIMPs., Comment: 5 pages, 4 figures; updated to match published version

Published
2013
Full Text
View/download PDF

21. Low-mass dark matter search with CDMSlite

Author

Massachusetts Institute of Technology. Department of Physics, Leder, Alexander Friedrich, Agnese, R., Anderson, A. J., Aralis, T., Aramaki, T., Arnquist, I. J., Baker, W., Balakishiyeva, D., Barker, D., Basu Thakur, R., Bauer, D. A., Binder, T., Bowles, M. A., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Calkins, R., Cartaro, C., Cerdeño, D. G., Chang, Y., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fascione, E., Figueroa-Feliciano, E., Fritts, M., Gerbier, G., Ghaith, M., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hong, Z., Hoppe, E. W., Hsu, L., Huber, M. E., Iyer, V., Jardin, D., Jastram, A., Jena, C., Kelsey, M. H., Kennedy, A., Kubik, A., Kurinsky, N. A., Loer, B., Lopez Asamar, E., Lukens, P., MacDonell, D., Mahapatra, R., Mandic, V., Mast, N., Miller, E. H., Mirabolfathi, N., Moffatt, R. A., Mohanty, B., Morales Mendoza, J. D., Nelson, J., Orrell, J. L., Oser, S. M., Page, K., Page, W. A., Partridge, R., Pepin, M., Peñalver Martinez, M., Phipps, A., Poudel, S., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Reynolds, T., Roberts, A., Robinson, A. E., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Senapati, K., Serfass, B., Speller, D., Stein, M., Street, J., Tanaka, H. A., Toback, D., Underwood, R., Villano, A. N., von Krosigk, B., Welliver, B., Wilson, J. S., Wilson, M. J., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., Zhang, X., Zhao, X., Massachusetts Institute of Technology. Department of Physics, Leder, Alexander Friedrich, Agnese, R., Anderson, A. J., Aralis, T., Aramaki, T., Arnquist, I. J., Baker, W., Balakishiyeva, D., Barker, D., Basu Thakur, R., Bauer, D. A., Binder, T., Bowles, M. A., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Calkins, R., Cartaro, C., Cerdeño, D. G., Chang, Y., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fascione, E., Figueroa-Feliciano, E., Fritts, M., Gerbier, G., Ghaith, M., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hong, Z., Hoppe, E. W., Hsu, L., Huber, M. E., Iyer, V., Jardin, D., Jastram, A., Jena, C., Kelsey, M. H., Kennedy, A., Kubik, A., Kurinsky, N. A., Loer, B., Lopez Asamar, E., Lukens, P., MacDonell, D., Mahapatra, R., Mandic, V., Mast, N., Miller, E. H., Mirabolfathi, N., Moffatt, R. A., Mohanty, B., Morales Mendoza, J. D., Nelson, J., Orrell, J. L., Oser, S. M., Page, K., Page, W. A., Partridge, R., Pepin, M., Peñalver Martinez, M., Phipps, A., Poudel, S., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Reynolds, T., Roberts, A., Robinson, A. E., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Senapati, K., Serfass, B., Speller, D., Stein, M., Street, J., Tanaka, H. A., Toback, D., Underwood, R., Villano, A. N., von Krosigk, B., Welliver, B., Wilson, J. S., Wilson, M. J., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., Zhang, X., and Zhao, X.

Abstract

The SuperCDMS experiment is designed to directly detect weakly interacting massive particles (WIMPs) that may constitute the dark matter in our Galaxy. During its operation at the Soudan Underground Laboratory, germanium detectors were run in the CDMSlite mode to gather data sets with sensitivity specifically for WIMPs with masses <10 GeV/c[superscript 2]. In this mode, a higher detector-bias voltage is applied to amplify the phonon signals produced by drifting charges. This paper presents studies of the experimental noise and its effect on the achievable energy threshold, which is demonstrated to be as low as 56 eV[subscript ee] (electron equivalent energy). The detector-biasing configuration is described in detail, with analysis corrections for voltage variations to the level of a few percent. Detailed studies of the electric-field geometry, and the resulting successful development of a fiducial parameter, eliminate poorly measured events, yielding an energy resolution ranging from ∼9 eV[subscript ee] at 0 keV to 101 eV[subscript ee] at ∼10 keV[subscript ee]. New results are derived for astrophysical uncertainties relevant to the WIMP-search limits, specifically examining how they are affected by variations in the most probable WIMP velocity and the Galactic escape velocity. These variations become more important for WIMP masses below 10 GeV/c[superscript 2]. Finally, new limits on spin-dependent low-mass WIMP-nucleon interactions are derived, with new parameter space excluded for WIMP masses ≲3 GeV/c[superscript 2]., National Science Foundation (U.S.), United States. Department of Energy, Fermi National Accelerator Laboratory (URA Visiting Scholar Award 13-S-04), Natural Sciences and Engineering Research Council of Canada, Spain. Ministerio de Economía y Competitividad

Published
2018

22. Projected sensitivity of the SuperCDMS SNOLAB experiment

Author

Massachusetts Institute of Technology. Department of Physics, Anderson, Adam Jonathan, Agnese, R., Aramaki, T., Arnquist, I., Baker, W., Barker, D., Basu Thakur, R., Bauer, D. A., Borgland, A., Bowles, M. A., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Calkins, R., Cartaro, C., Cerdeño, D. G., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Figueroa-Feliciano, E., Fritts, M., Gerbier, G., Ghaith, M., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hofer, T., Holmgren, D., Hong, Z., Hoppe, E., Hsu, L., Huber, M. E., Iyer, V., Jardin, D., Jastram, A., Kelsey, M. H., Kennedy, A., Kubik, A., Kurinsky, N. A., Leder, A., Loer, B., Lopez Asamar, E., Lukens, P., Mahapatra, R., Mandic, V., Mast, N., Mirabolfathi, N., Moffatt, R. A., Morales Mendoza, J. D., Orrell, J. L., Oser, S. M., Page, K., Page, W. A., Partridge, R., Pepin, M., Phipps, A., Poudel, S., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Roberts, A., Robinson, A. E., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Serfass, B., Speller, D., Stein, M., Street, J., Tanaka, H. A., Toback, D., Underwood, R., Villano, A. N., von Krosigk, B., Welliver, B., Wilson, J. S., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., Zhang, X., Zhao, X., Massachusetts Institute of Technology. Department of Physics, Anderson, Adam Jonathan, Agnese, R., Aramaki, T., Arnquist, I., Baker, W., Barker, D., Basu Thakur, R., Bauer, D. A., Borgland, A., Bowles, M. A., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Calkins, R., Cartaro, C., Cerdeño, D. G., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Figueroa-Feliciano, E., Fritts, M., Gerbier, G., Ghaith, M., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hofer, T., Holmgren, D., Hong, Z., Hoppe, E., Hsu, L., Huber, M. E., Iyer, V., Jardin, D., Jastram, A., Kelsey, M. H., Kennedy, A., Kubik, A., Kurinsky, N. A., Leder, A., Loer, B., Lopez Asamar, E., Lukens, P., Mahapatra, R., Mandic, V., Mast, N., Mirabolfathi, N., Moffatt, R. A., Morales Mendoza, J. D., Orrell, J. L., Oser, S. M., Page, K., Page, W. A., Partridge, R., Pepin, M., Phipps, A., Poudel, S., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Roberts, A., Robinson, A. E., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Serfass, B., Speller, D., Stein, M., Street, J., Tanaka, H. A., Toback, D., Underwood, R., Villano, A. N., von Krosigk, B., Welliver, B., Wilson, J. S., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., Zhang, X., and Zhao, X.

Abstract

SuperCDMS SNOLAB will be a next-generation experiment aimed at directly detecting low-mass particles (with masses ≤10 GeV/c^{2}) that may constitute dark matter by using cryogenic detectors of two types (HV and iZIP) and two target materials (germanium and silicon). The experiment is being designed with an initial sensitivity to nuclear recoil cross sections ∼1×10^{-43} cm^{2} for a dark matter particle mass of 1 GeV/c^{2}, and with capacity to continue exploration to both smaller masses and better sensitivities. The phonon sensitivity of the HV detectors will be sufficient to detect nuclear recoils from sub-GeV dark matter. A detailed calibration of the detector response to low-energy recoils will be needed to optimize running conditions of the HV detectors and to interpret their data for dark matter searches. Low-activity shielding, and the depth of SNOLAB, will reduce most backgrounds, but cosmogenically produced ^{3}H and naturally occurring ^{32}Si will be present in the detectors at some level. Even if these backgrounds are 10 times higher than expected, the science reach of the HV detectors would be over 3 orders of magnitude beyond current results for a dark matter mass of 1 GeV/c^{2}. The iZIP detectors are relatively insensitive to variations in detector response and backgrounds, and will provide better sensitivity for dark matter particles with masses ≳5 GeV/c^{2}. The mix of detector types (HV and iZIP), and targets (germanium and silicon), planned for the experiment, as well as flexibility in how the detectors are operated, will allow us to maximize the low-mass reach, and understand the backgrounds that the experiment will encounter. Upgrades to the experiment, perhaps with a variety of ultra-low-background cryogenic detectors, will extend dark matter sensitivity down to the “neutrino floor,” where coherent scatters of solar neutrinos become a limiting background., National Science Foundation (U.S.), United States. Department of Energy

Published
2017

23. First direct limits on lightly ionizing particles with electric charge less than e/6

Author

Agnese, R., Anderson, A. J., Balakishiyeva, D., Basu Thakur, R., Bauer, D. A., Billard, J., Borgland, A., Bowles, M. A., Brandt, D., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Cerdeno, D. G., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Figueroa-Feliciano, E., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hertel, S. A., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kennedy, A., Kiveni, M., Koch, K., Leder, A., Loer, B., Lopez Asamar, E., Mahapatra, R., Mandic, V., Martinez, C., McCarthy, K. A., Mirabolfathi, N., Moffatt, R. A., Moore, D. C., Nelson, H., Nelson, R. H., Ogburn, R. W., Page, K., Page, W. A., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Ricci, Y., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Serfass, B., Shank, B., Speller, D., Upadhyayula, S., Villano, A. N., Welliver, B., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., Zhang, J., (CDMS Collaboration), and UAM. Departamento de Física Teórica

Subjects
General Physics, Particle physics, Cosmology and Nongalactic Astrophysics (astro-ph.CO), Physics - Instrumentation and Detectors, CDMS Collaboration, Direct detection, Dark matter, FOS: Physical sciences, General Physics and Astronomy, Parameter space, Electric charge, Mathematical Sciences, High Energy Physics - Experiment, Standard Model, Relativistic particle, Nuclear physics, High Energy Physics - Experiment (hep-ex), Engineering, physics.ins-det, High Energy Astrophysical Phenomena (astro-ph.HE), astro-ph.HE, Physics, Stacked detectors, hep-ex, Fractional charges, Física, Charge (physics), Instrumentation and Detectors (physics.ins-det), Ionizing particles, Physical Sciences, astro-ph.CO, Subatomic particle, Cryogenic Dark Matter Search, Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

Artículo escrito por muchos autores, sólo se referencian el primero, los autores que firman como Universidad Autónoma de Madrid y el grupo de colaboración en el caso de que aparezca en el artículo, While the standard model of particle physics does not include free particles with fractional charge, experimental searches have not ruled out their existence. We report results from the Cryogenic Dark Matter Search (CDMS II) experiment that give the first direct-detection limits for cosmogenically produced relativistic particles with electric charge lower than e/6. A search for tracks in the six stacked detectors of each of two of the CDMS II towers finds no candidates, thereby excluding new parameter space for particles with electric charges between e/6 and e/200, This work is supported in part by the National Science Foundation, by the U.S. Department of Energy, by NSERC Canada, and by MultiDark (Spanish MINECO). Fermilab is operated by the Fermi Research Alliance, LLC under Contract No. De-AC02-07CH11359. SLAC is operated under Contract No. DE-AC02-76SF00515 with the U.S. Department of Energy

Published
2014
Full Text
View/download PDF

24. New Results from the Search for Low-Mass Weakly Interacting Massive Particles with the CDMS Low Ionization Threshold Experiment

Author

Massachusetts Institute of Technology. Department of Physics, Billard, Julien, Leder, Alexander Friedrich, Agnese, R., Anderson, A. J., Aramaki, T., Asai, M., Baker, W., Balakishiyeva, D., Barker, D., Basu Thakur, R., Bauer, D. A., Borgland, A., Bowles, M. A., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Calkins, R., Cerdeno, D. G., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Figueroa-Feliciano, E., Ghaith, M., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jardin, D., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kennedy, A., Loer, B., Lopez Asamar, E., Lukens, P., Mahapatra, R., Mandic, V., Mast, N., Mirabolfathi, N., Moffatt, R. A., Morales Mendoza, J. D., Oser, S. M., Page, K., Page, W. A., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Ricci, Y., Roberts, A., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Serfass, B., Shank, B., Speller, D., Toback, D., Underwood, R., Upadhyayula, S., Villano, A. N., Welliver, B., Wilson, J. S., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., Zhang, J., Massachusetts Institute of Technology. Department of Physics, Billard, Julien, Leder, Alexander Friedrich, Agnese, R., Anderson, A. J., Aramaki, T., Asai, M., Baker, W., Balakishiyeva, D., Barker, D., Basu Thakur, R., Bauer, D. A., Borgland, A., Bowles, M. A., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Calkins, R., Cerdeno, D. G., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Figueroa-Feliciano, E., Ghaith, M., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jardin, D., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kennedy, A., Loer, B., Lopez Asamar, E., Lukens, P., Mahapatra, R., Mandic, V., Mast, N., Mirabolfathi, N., Moffatt, R. A., Morales Mendoza, J. D., Oser, S. M., Page, K., Page, W. A., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Ricci, Y., Roberts, A., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Serfass, B., Shank, B., Speller, D., Toback, D., Underwood, R., Upadhyayula, S., Villano, A. N., Welliver, B., Wilson, J. S., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., and Zhang, J.

Abstract

The CDMS low ionization threshold experiment (CDMSlite) uses cryogenic germanium detectors operated at a relatively high bias voltage to amplify the phonon signal in the search for weakly interacting massive particles (WIMPs). Results are presented from the second CDMSlite run with an exposure of 70 kg day, which reached an energy threshold for electron recoils as low as 56 eV. A fiducialization cut reduces backgrounds below those previously reported by CDMSlite. New parameter space for the WIMP-nucleon spin-independent cross section is excluded for WIMP masses between 1.6 and 5.5 GeV/c[superscript 2]., National Science Foundation (U.S.), United States. Dept. of Energy, Fermi National Accelerator Laboratory (Visiting Scholar Award 13-S-04)

Published
2016

25. Detector Fabrication Yield for SuperCDMS Soudan

Author

Lincoln Laboratory, Massachusetts Institute of Technology. Department of Physics, Anderson, Adam Jonathan, Figueroa-Feliciano, Enectali, Hertel, Scott A, Leman, Steven W., McCarthy, Kevin Ahmad, Brink, P. L, Balakishiyeva, D., Bauer, D. A, Beaty, J., Brandt, D., Cabrera, B., Chagani, H., Cherry, M., Cooley, J., do Couto e Silva, E., Cushman, P., Daal, M., Doughty, T., Fritts, M., Godfrey, G., Golwala, S. R, Hall, J., Harris, R., Hines, B. A, Hsu, L., Huber, M. E, Kamaev, O., Kara, B., Kenany, S. A, Leman, S. W, Mahapatra, R., Mandic, V., Mirabolfathi, N., Novak, L., Partridge, R., Pyle, M., Qiu, H., Radpour, R., Rau, W., Reisetter, A., Resch, R., Saab, T., Sadoulet, B., Sander, J., Schmitt, R., Schnee, R. W, Scorza, S., Seitz, D. N, Serfass, B., Shank, B., Tomada, A., Villano, A., Welliver, B., Yen, J. J, Young, B. A, Zhang, J., Lincoln Laboratory, Massachusetts Institute of Technology. Department of Physics, Anderson, Adam Jonathan, Figueroa-Feliciano, Enectali, Hertel, Scott A, Leman, Steven W., McCarthy, Kevin Ahmad, Brink, P. L, Balakishiyeva, D., Bauer, D. A, Beaty, J., Brandt, D., Cabrera, B., Chagani, H., Cherry, M., Cooley, J., do Couto e Silva, E., Cushman, P., Daal, M., Doughty, T., Fritts, M., Godfrey, G., Golwala, S. R, Hall, J., Harris, R., Hines, B. A, Hsu, L., Huber, M. E, Kamaev, O., Kara, B., Kenany, S. A, Leman, S. W, Mahapatra, R., Mandic, V., Mirabolfathi, N., Novak, L., Partridge, R., Pyle, M., Qiu, H., Radpour, R., Rau, W., Reisetter, A., Resch, R., Saab, T., Sadoulet, B., Sander, J., Schmitt, R., Schnee, R. W, Scorza, S., Seitz, D. N, Serfass, B., Shank, B., Tomada, A., Villano, A., Welliver, B., Yen, J. J, Young, B. A, and Zhang, J.

Abstract

The SuperCDMS collaboration is presently operating a 9 kg Ge payload at the Soudan Underground Laboratory in their direct search for dark matter. The Ge detectors utilize double-sided athermal phonon sensors with an interdigitated electrode structure (iZIPs) to reject near-surface electron-recoil events. These detectors each have a mass of 0.6 kg and were fabricated with photolithographic techniques. The detector fabrication advances required and the production yield encountered are described., United States. Dept. of Energy, National Science Foundation (U.S.)

Published
2016

26. Improved WIMP-search reach of the CDMS II germanium data

Author

Massachusetts Institute of Technology. Department of Physics, MIT Kavli Institute for Astrophysics and Space Research, Anderson, Adam Jonathan, Billard, Julien, Figueroa-Feliciano, Enectali, Hertel, Scott A., Leder, Alexander Friedrich, McCarthy, Kevin Ahmad, Agnese, R., Asai, M., Balakishiyeva, D., Barker, D., Basu Thakur, R., Bauer, D. A., Borgland, A., Bowles, M. A., Brandt, D., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Calkins, R., Cerdeño, D. G., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jardin, D. M., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kennedy, A., Kiveni, M., Koch, K., Loer, B., Lopez Asamar, E., Lukens, P., Mahapatra, R., Mandic, V., Mirabolfathi, N., Moffatt, R. A., Oser, S. M., Page, K., Page, W. A., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Ricci, Y., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Serfass, B., Shank, B., Speller, D., Toback, D., Upadhyayula, S., Villano, A. N., Welliver, B., Wilson, J. S., Wright, D. H., Yang, X., Yellin, S., Yen, J. J., Young, B. A., Zhang, J., Massachusetts Institute of Technology. Department of Physics, MIT Kavli Institute for Astrophysics and Space Research, Anderson, Adam Jonathan, Billard, Julien, Figueroa-Feliciano, Enectali, Hertel, Scott A., Leder, Alexander Friedrich, McCarthy, Kevin Ahmad, Agnese, R., Asai, M., Balakishiyeva, D., Barker, D., Basu Thakur, R., Bauer, D. A., Borgland, A., Bowles, M. A., Brandt, D., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Calkins, R., Cerdeño, D. G., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jardin, D. M., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kennedy, A., Kiveni, M., Koch, K., Loer, B., Lopez Asamar, E., Lukens, P., Mahapatra, R., Mandic, V., Mirabolfathi, N., Moffatt, R. A., Oser, S. M., Page, K., Page, W. A., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Ricci, Y., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Serfass, B., Shank, B., Speller, D., Toback, D., Upadhyayula, S., Villano, A. N., Welliver, B., Wilson, J. S., Wright, D. H., Yang, X., Yellin, S., Yen, J. J., Young, B. A., and Zhang, J.

Abstract

CDMS II data from the five-tower runs at the Soudan Underground Laboratory were reprocessed with an improved charge-pulse fitting algorithm. Two new analysis techniques to reject surface-event backgrounds were applied to the 612 kg days germanium-detector weakly interacting massive particle (WIMP)-search exposure. An extended analysis was also completed by decreasing the 10 keV analysis threshold to ~5 keV, to increase sensitivity near a WIMP mass of 8 GeV/c[superscript 2]. After unblinding, there were zero candidate events above a deposited energy of 10 keV and six events in the lower-threshold analysis. This yielded minimum WIMP-nucleon spin-independent scattering cross-section limits of 1.8 × 10[superscript −44] and 1.18 × 10[superscript −41] at 90% confidence for 60 and 8.6 GeV/c[superscript 2] WIMPs, respectively. This improves the previous CDMS II result by a factor of 2.4 (2.7) for 60 (8.6) GeV/c[superscript 2] WIMPs., National Science Foundation (U.S.), United States. Dept. of Energy, Natural Sciences and Engineering Research Council of Canada, Spain. Ministerio de Economia y Competitividad (MultiDark)

Published
2015

27. Maximum likelihood analysis of low energy CDMS II germanium data

Author

Massachusetts Institute of Technology. Department of Physics, MIT Kavli Institute for Astrophysics and Space Research, Anderson, Adam Jonathan, Billard, Julien, Figueroa-Feliciano, Enectali, Hertel, Scott Alexander, Leder, Alexander Friedrich, McCarthy, Kevin Ahmad, Agnese, R., Balakishiyeva, D., Basu Thakur, R., Bauer, D. A., Borgland, A., Bowles, M. A., Brandt, D., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Cerdeno, D. G., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Fritts, M., Godfrey, G. L., Golwala, S. R., Graham, M., Hall, J., Harris, H. R., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kennedy, A., Kiveni, M., Koch, K., Loer, B., Lopez Asamar, E., Mahapatra, R., Mandic, V., Martinez, C., Mirabolfathi, N., Moffatt, R. A., Moore, D. C., Nelson, R. H., Oser, S. M., Page, K., Page, W. A., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Ricci, Y., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Serfass, B., Shank, B., Speller, D., Upadhyayula, S., Villano, A. N., Welliver, B., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., Zhang, J., Massachusetts Institute of Technology. Department of Physics, MIT Kavli Institute for Astrophysics and Space Research, Anderson, Adam Jonathan, Billard, Julien, Figueroa-Feliciano, Enectali, Hertel, Scott Alexander, Leder, Alexander Friedrich, McCarthy, Kevin Ahmad, Agnese, R., Balakishiyeva, D., Basu Thakur, R., Bauer, D. A., Borgland, A., Bowles, M. A., Brandt, D., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Cerdeno, D. G., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Fritts, M., Godfrey, G. L., Golwala, S. R., Graham, M., Hall, J., Harris, H. R., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kennedy, A., Kiveni, M., Koch, K., Loer, B., Lopez Asamar, E., Mahapatra, R., Mandic, V., Martinez, C., Mirabolfathi, N., Moffatt, R. A., Moore, D. C., Nelson, R. H., Oser, S. M., Page, K., Page, W. A., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Ricci, Y., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Serfass, B., Shank, B., Speller, D., Upadhyayula, S., Villano, A. N., Welliver, B., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., and Zhang, J.

Abstract

We report on the results of a search for a Weakly Interacting Massive Particle (WIMP) signal in low-energy data of the Cryogenic Dark Matter Search experiment using a maximum likelihood analysis. A background model is constructed using geant4 to simulate the surface-event background from [superscript 210]Pb decay-chain events, while using independent calibration data to model the gamma background. Fitting this background model to the data results in no statistically significant WIMP component. In addition, we perform fits using an analytic ad hoc background model proposed by Collar and Fields, who claimed to find a large excess of signal-like events in our data. We confirm the strong preference for a signal hypothesis in their analysis under these assumptions, but excesses are observed in both single- and multiple-scatter events, which implies the signal is not caused by WIMPs, but rather reflects the inadequacy of their background model., United States. Dept. of Energy, National Science Foundation (U.S.)

Published
2015

28. Dark matter effective field theory scattering in direct detection experiments

Author

Massachusetts Institute of Technology. Department of Physics, MIT Kavli Institute for Astrophysics and Space Research, Anderson, Adam Jonathan, Billard, Julien, Figueroa-Feliciano, Enectali, Leder, Alexander Friedrich, McCarthy, Kevin Ahmad, Schneck, K., Cabrera, B., Cerdeno, D. G., Mandic, V., Rogers, H. E., Agnese, R., Asai, M., Balakishiyeva, D., Barker, D., Basu Thakur, R., Bauer, D. A., Borgland, A., Brandt, D., Brink, P. L., Bunker, R., Caldwell, D. O., Calkins, R., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jardin, D. M., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kennedy, A., Loer, B., Lopez Asamar, E., Lukens, P., Mahapatra, R., Mirabolfathi, N., Moffatt, R. A., Morales Mendoza, J. D., Oser, S. M., Page, K., Page, W. A., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Ricci, Y., Roberts, A., Saab, T., Sadoulet, B., Sander, J., Schnee, R. W., Scorza, S., Serfass, B., Shank, B., Speller, D., Toback, D., Upadhyayula, S., Villano, A. N., Welliver, B., Wilson, J. S., Wright, D. H., Yang, X., Yellin, S., Yen, J. J., Young, B. A., Zhang, J., Massachusetts Institute of Technology. Department of Physics, MIT Kavli Institute for Astrophysics and Space Research, Anderson, Adam Jonathan, Billard, Julien, Figueroa-Feliciano, Enectali, Leder, Alexander Friedrich, McCarthy, Kevin Ahmad, Schneck, K., Cabrera, B., Cerdeno, D. G., Mandic, V., Rogers, H. E., Agnese, R., Asai, M., Balakishiyeva, D., Barker, D., Basu Thakur, R., Bauer, D. A., Borgland, A., Brandt, D., Brink, P. L., Bunker, R., Caldwell, D. O., Calkins, R., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jardin, D. M., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kennedy, A., Loer, B., Lopez Asamar, E., Lukens, P., Mahapatra, R., Mirabolfathi, N., Moffatt, R. A., Morales Mendoza, J. D., Oser, S. M., Page, K., Page, W. A., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Ricci, Y., Roberts, A., Saab, T., Sadoulet, B., Sander, J., Schnee, R. W., Scorza, S., Serfass, B., Shank, B., Speller, D., Toback, D., Upadhyayula, S., Villano, A. N., Welliver, B., Wilson, J. S., Wright, D. H., Yang, X., Yellin, S., Yen, J. J., Young, B. A., and Zhang, J.

Abstract

We examine the consequences of the effective field theory (EFT) of dark matter–nucleon scattering for current and proposed direct detection experiments. Exclusion limits on EFT coupling constants computed using the optimum interval method are presented for SuperCDMS Soudan, CDMS II, and LUX, and the necessity of combining results from multiple experiments in order to determine dark matter parameters is discussed. We demonstrate that spectral differences between the standard dark matter model and a general EFT interaction can produce a bias when calculating exclusion limits and when developing signal models for likelihood and machine learning techniques. We also discuss the implications of the EFT for the next-generation (G2) direct detection experiments and point out regions of complementarity in the EFT parameter space., National Science Foundation (U.S.), United States. Dept. of Energy, Natural Sciences and Engineering Research Council of Canada, Spain. Ministerio de Economia y Competitividad (MultiDark)

Published
2015

29. First Direct Limits on Lightly Ionizing Particles with Electric Charge Less than e/6

Author

Massachusetts Institute of Technology. Department of Physics, Anderson, Adam Jonathan, Billard, Julien, Figueroa-Feliciano, Enectali, Hertel, Scott Alexander, Leder, Alexander Friedrich, McCarthy, Kevin Ahmad, Agnese, R., Balakishiyeva, D., Basu Thakur, R., Bauer, D. A., Borgland, A., Bowles, M. A., Brandt, D., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Cerdeno, D. G., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kennedy, A., Kiveni, M., Koch, K., Loer, B., Lopez Asamar, E., Mahapatra, R., Mandic, V., Martinez, C., Mirabolfathi, N., Moffatt, R. A., Moore, D. C., Nelson, H., Nelson, R. H., Ogburn, R. W., Page, K., Page, W. A., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Ricci, Y., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Serfass, B., Shank, B., Speller, D., Upadhyayula, S., Villano, A. N., Welliver, B., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., Zhang, J., Massachusetts Institute of Technology. Department of Physics, Anderson, Adam Jonathan, Billard, Julien, Figueroa-Feliciano, Enectali, Hertel, Scott Alexander, Leder, Alexander Friedrich, McCarthy, Kevin Ahmad, Agnese, R., Balakishiyeva, D., Basu Thakur, R., Bauer, D. A., Borgland, A., Bowles, M. A., Brandt, D., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Cerdeno, D. G., Chagani, H., Chen, Y., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., Di Stefano, P. C. F., Doughty, T., Esteban, L., Fallows, S., Godfrey, G. L., Golwala, S. R., Hall, J., Harris, H. R., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kennedy, A., Kiveni, M., Koch, K., Loer, B., Lopez Asamar, E., Mahapatra, R., Mandic, V., Martinez, C., Mirabolfathi, N., Moffatt, R. A., Moore, D. C., Nelson, H., Nelson, R. H., Ogburn, R. W., Page, K., Page, W. A., Partridge, R., Pepin, M., Phipps, A., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Ricci, Y., Rogers, H. E., Saab, T., Sadoulet, B., Sander, J., Schneck, K., Schnee, R. W., Scorza, S., Serfass, B., Shank, B., Speller, D., Upadhyayula, S., Villano, A. N., Welliver, B., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., and Zhang, J.

Abstract

While the standard model of particle physics does not include free particles with fractional charge, experimental searches have not ruled out their existence. We report results from the Cryogenic Dark Matter Search (CDMS II) experiment that give the first direct-detection limits for cosmogenically produced relativistic particles with electric charge lower than e/6. A search for tracks in the six stacked detectors of each of two of the CDMS II towers finds no candidates, thereby excluding new parameter space for particles with electric charges between e/6 and e/200., National Science Foundation (U.S.), United States. Dept. of Energy, Natural Sciences and Engineering Research Council of Canada, Spain. Ministerio de Economia y Competividad (MultiDark)

Published
2015

30. Search for Low-Mass Weakly Interacting Massive Particles with SuperCDMS

Author

Kavli Institute for Astrophysics and Space Research, Massachusetts Institute of Technology. Department of Physics, Anderson, Adam Jonathan, Billard, Julien, Figueroa-Feliciano, Enectali, Hertel, Scott Alexander, Leder, Alexander Friedrich, McCarthy, Kevin Ahmad, Agnese, R., Asai, M., Balakishiyeva, D., Basu Thakur, R., Bauer, D. A., Beaty, J., Borgland, A., Bowles, M. A., Brandt, D., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Cerdeno, D. G., Chagani, H., Chen, Y., Cherry, M., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., DeVaney, D., Di Stefano, P. C. F., Silva, E. Do Couto E, Doughty, T., Esteban, L., Fallows, S., Godfrey, G. L., Golwala, S. R., Hall, J., Hansen, S., Harris, H. R., Hines, B. A., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kenany, S., Kennedy, A., Kiveni, M., Koch, K., Loer, B., Lopez Asamar, E., Mahapatra, R., Mandic, V., Martinez, C., Mirabolfathi, N., Moffatt, R. A., Nelson, R. H., Novak, L., Page, K., Partridge, R., Pepin, M., Phipps, A., Platt, M., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Resch, R. W., Ricci, Y., Ruschman, M., Saab, T., Sadoulet, B., Sander, J., Schmitt, R. L., Schneck, K., Schnee, R. W., Scorza, S., Seitz, D. N., Serfass, B., Shank, B., Speller, D., Tomada, A., Upadhyayula, S., Villano, A. N., Welliver, B., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., Zhang, J., Kavli Institute for Astrophysics and Space Research, Massachusetts Institute of Technology. Department of Physics, Anderson, Adam Jonathan, Billard, Julien, Figueroa-Feliciano, Enectali, Hertel, Scott Alexander, Leder, Alexander Friedrich, McCarthy, Kevin Ahmad, Agnese, R., Asai, M., Balakishiyeva, D., Basu Thakur, R., Bauer, D. A., Beaty, J., Borgland, A., Bowles, M. A., Brandt, D., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Cerdeno, D. G., Chagani, H., Chen, Y., Cherry, M., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., DeVaney, D., Di Stefano, P. C. F., Silva, E. Do Couto E, Doughty, T., Esteban, L., Fallows, S., Godfrey, G. L., Golwala, S. R., Hall, J., Hansen, S., Harris, H. R., Hines, B. A., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kenany, S., Kennedy, A., Kiveni, M., Koch, K., Loer, B., Lopez Asamar, E., Mahapatra, R., Mandic, V., Martinez, C., Mirabolfathi, N., Moffatt, R. A., Nelson, R. H., Novak, L., Page, K., Partridge, R., Pepin, M., Phipps, A., Platt, M., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Resch, R. W., Ricci, Y., Ruschman, M., Saab, T., Sadoulet, B., Sander, J., Schmitt, R. L., Schneck, K., Schnee, R. W., Scorza, S., Seitz, D. N., Serfass, B., Shank, B., Speller, D., Tomada, A., Upadhyayula, S., Villano, A. N., Welliver, B., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., and Zhang, J.

Abstract

We report a first search for weakly interacting massive particles (WIMPs) using the background rejection capabilities of SuperCDMS. An exposure of 577 kg days was analyzed for WIMPs with mass < 30 GeV/c[superscript 2], with the signal region blinded. Eleven events were observed after unblinding. We set an upper limit on the spin-independent WIMP-nucleon cross section of 1.2 × 10[superscript −42] cm[superscript 2] at 8 GeV/c[superscript 2]. This result is in tension with WIMP interpretations of recent experiments and probes new parameter space for WIMP-nucleon scattering for WIMP masses <6 GeV/c[superscript 2]., National Science Foundation (U.S.), United States. Dept. of Energy

Published
2014

31. Search for Low-Mass Weakly Interacting Massive Particles with SuperCDMS

Author

Massachusetts Institute of Technology. Department of Physics, MIT Kavli Institute for Astrophysics and Space Research, Anderson, Adam Jonathan, Billard, Julien, Figueroa-Feliciano, Enectali, Hertel, Scott Alexander, Leder, Alexander Friedrich, McCarthy, Kevin Ahmad, Agnese, R., Asai, M., Balakishiyeva, D., Basu Thakur, R., Bauer, D. A., Beaty, J., Borgland, A., Bowles, M. A., Brandt, D., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Cerdeno, D. G., Chagani, H., Chen, Y., Cherry, M., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., DeVaney, D., Di Stefano, P. C. F., Silva, E. Do Couto E, Doughty, T., Esteban, L., Fallows, S., Godfrey, G. L., Golwala, S. R., Hall, J., Hansen, S., Harris, H. R., Hines, B. A., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kenany, S., Kennedy, A., Kiveni, M., Koch, K., Loer, B., Lopez Asamar, E., Mahapatra, R., Mandic, V., Martinez, C., Mirabolfathi, N., Moffatt, R. A., Nelson, R. H., Novak, L., Page, K., Partridge, R., Pepin, M., Phipps, A., Platt, M., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Resch, R. W., Ricci, Y., Ruschman, M., Saab, T., Sadoulet, B., Sander, J., Schmitt, R. L., Schneck, K., Schnee, R. W., Scorza, S., Seitz, D. N., Serfass, B., Shank, B., Speller, D., Tomada, A., Upadhyayula, S., Villano, A. N., Welliver, B., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., Zhang, J., Massachusetts Institute of Technology. Department of Physics, MIT Kavli Institute for Astrophysics and Space Research, Anderson, Adam Jonathan, Billard, Julien, Figueroa-Feliciano, Enectali, Hertel, Scott Alexander, Leder, Alexander Friedrich, McCarthy, Kevin Ahmad, Agnese, R., Asai, M., Balakishiyeva, D., Basu Thakur, R., Bauer, D. A., Beaty, J., Borgland, A., Bowles, M. A., Brandt, D., Brink, P. L., Bunker, R., Cabrera, B., Caldwell, D. O., Cerdeno, D. G., Chagani, H., Chen, Y., Cherry, M., Cooley, J., Cornell, B., Crewdson, C. H., Cushman, P., Daal, M., DeVaney, D., Di Stefano, P. C. F., Silva, E. Do Couto E, Doughty, T., Esteban, L., Fallows, S., Godfrey, G. L., Golwala, S. R., Hall, J., Hansen, S., Harris, H. R., Hines, B. A., Hofer, T., Holmgren, D., Hsu, L., Huber, M. E., Jastram, A., Kamaev, O., Kara, B., Kelsey, M. H., Kenany, S., Kennedy, A., Kiveni, M., Koch, K., Loer, B., Lopez Asamar, E., Mahapatra, R., Mandic, V., Martinez, C., Mirabolfathi, N., Moffatt, R. A., Nelson, R. H., Novak, L., Page, K., Partridge, R., Pepin, M., Phipps, A., Platt, M., Prasad, K., Pyle, M., Qiu, H., Rau, W., Redl, P., Reisetter, A., Resch, R. W., Ricci, Y., Ruschman, M., Saab, T., Sadoulet, B., Sander, J., Schmitt, R. L., Schneck, K., Schnee, R. W., Scorza, S., Seitz, D. N., Serfass, B., Shank, B., Speller, D., Tomada, A., Upadhyayula, S., Villano, A. N., Welliver, B., Wright, D. H., Yellin, S., Yen, J. J., Young, B. A., and Zhang, J.

Abstract

We report a first search for weakly interacting massive particles (WIMPs) using the background rejection capabilities of SuperCDMS. An exposure of 577 kg days was analyzed for WIMPs with mass < 30 GeV/c[superscript 2], with the signal region blinded. Eleven events were observed after unblinding. We set an upper limit on the spin-independent WIMP-nucleon cross section of 1.2 × 10[superscript −42] cm[superscript 2] at 8 GeV/c[superscript 2]. This result is in tension with WIMP interpretations of recent experiments and probes new parameter space for WIMP-nucleon scattering for WIMP masses <6 GeV/c[superscript 2]., National Science Foundation (U.S.), United States. Dept. of Energy

Published
2014

36. The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB.

Author

Wang, J M, Chao, J R, Chen, W, Kuo, M L, Yen, J J, and Yang-Yen, H F

Abstract

mcl-1 is an immediate-early gene activated by the granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin 3 (IL-3) signaling pathways and plays an important role in the viability response of these cytokines. In this study, we demonstrated that cytokine stimulation of mcl-1 mRNA and protein expression were attenuated by pretreatment of cells with phosphatidylinositol 3-kinase (PI3-K) inhibitors. Reporter gene assays further showed that the PI3-K/Akt signaling pathway was involved in IL-3 activation of mcl-1 gene transcription. Analysis of the mcl-1 promoter revealed that both promoter elements, SIE at position -87 and CRE-2 at -70, contribute to IL-3 stimulation of mcl-1 gene expression. Although either the SIE site or the CRE-2 site alone was sufficient to confer IL-3 inducibility on a heterologous promoter, only IL-3 activation of the CRE-2 reporter was mediated via the PI3-K/Akt pathway. The SIE binding activity was constitutively high in cells deprived of or stimulated by IL-3. In contrast, the CRE-2 binding activity was low in cytokine-starved cells and was strongly induced within 1 h following cytokine treatment of cells. In addition, cytokine induction of the CRE-2 but not of the SIE binding activity was dependent on activation of the PI3-K/Akt signaling pathway. Lastly, we showed that CREB was one component of the CRE-2 binding complex and played a role in IL-3 activation of the mcl-1 reporter gene. Taken together, our results suggest that both PI3-K/Akt-dependent and -independent pathways contribute to the IL-3 activation of mcl-1 gene expression. Activation of mcl-1 by the PI3-K/Akt-dependent pathway is through a transcription factor complex containing CREB.

Published
1999

37. Cytokine receptor common beta chain as a potential activator of cytokine withdrawal-induced apoptosis.

Author

Lee, S F, Huang, H M, Chao, J R, Lin, S, Yang-Yen, H F, and Yen, J J

Abstract

Growth factors and cytokines play an important role in supporting cellular viability of various tissues during development due to their ability to suppress the default cell death program in each cell type. To date, neither the triggering molecule nor the transduction pathway of these default apoptosis programs is understood. In this study, we explored the possibility that cytokine receptors are involved in modulating cytokine withdrawal-induced apoptosis (CWIA) in hematopoietic cells. Expression of the exogenous cytokine receptor common beta chain (betac), but not the alpha chains, accelerated CWIA in multiple cytokine-dependent cell lines. Reduction of the expression level of endogenous betac by antisense transcripts resulted in prolonged survival during cytokine deprivation, suggesting a critical role of betac in modulating CWIA. Fine mapping of the betac subunit revealed that a membrane-proximal cytoplasmic sequence, designated the death enhancement region (DER), was critical to the death acceleration effect of betac. Furthermore, DER accelerated cell death either as a chimeric membrane protein or as a cytosolic protein, suggesting that DER functions independently of the cytokine receptor and membrane anchorage. Cross-linking of the chimeric membrane-bound DER molecules by antibody or of the FK506-binding protein-DER fusion protein by a synthetic dimerizing agent, AP1510, did not abrogate the death acceleration effect. Transient transfection assays further indicated that DER promoted cell death in the absence of serum in the nonhematopoietic 293 cell line. In summary, our data suggest that betac plays an important role in modulating CWIA via an anchorage-independent and aggregation-insensitive mechanism. These findings may facilitate further studies on the signaling pathways of CWIA.

Published
1999

38. mcl-1 is an immediate-early gene activated by the granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling pathway and is one component of the GM-CSF viability response.

Author

Chao, J R, Wang, J M, Lee, S F, Peng, H W, Lin, Y H, Chou, C H, Li, J C, Huang, H M, Chou, C K, Kuo, M L, Yen, J J, and Yang-Yen, H F

Abstract

mcl-1, a bcl-2 family member, was originally identified as an early gene induced during differentiation of ML-1 myeloid leukemia cells. In the present study, we demonstrate that Mcl-1 is tightly regulated by the granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling pathway. Upon deprivation of survival factor from TF-1 myeloid progenitor cells, Mcl-1 levels quickly dropped prior to visible detection of apoptosis of these cells. Upon restimulation of these deprived cells with GM-CSF, the mcl-1 mRNA was immediately induced and its protein product was accordingly resynthesized. Analysis with Ba/F3 cells expressing various truncation mutants of the GM-CSF receptor revealed that the membrane distal region between amino acids 573 and 755 of the receptor beta chain was required for mcl-1 induction. Transient-transfection assays with luciferase reporter genes driven by various regions of the mcl-1 promoter demonstrated that the upstream sequence between -197 and -69 is responsible for cytokine activation of the mcl-1 gene. Overexpression of mcl-1 delayed but did not completely prevent apoptosis of cells triggered by cytokine withdrawal. Its down regulation by antisense constructs overcame, at least partially, the survival activity of GM-CSF and induced the apoptosis of TF-1 cells. Taken together, these results suggest that mcl-1 is an immediate-early gene activated by the cytokine receptor signaling pathway and is one component of the GM-CSF viability response.

Published
1998

39. CREB is one component of the binding complex of the Ces-2/E2A-HLF binding element and is an integral part of the interleukin-3 survival signal.

Author

Chen W, Yu YL, Lee SF, Chiang YJ, Chao JR, Huang JH, Chiong JH, Huang CJ, Lai MZ, Yang-Yen HF, and Yen JJ

Subjects
Animals, Basic-Leucine Zipper Transcription Factors, Caenorhabditis elegans, Cell Line, Cell Survival, Cyclic AMP metabolism, Cyclic AMP-Dependent Protein Kinases metabolism, DNA-Binding Proteins genetics, Genes, Reporter, Helminth Proteins genetics, Hematopoietic Stem Cells cytology, Humans, Mice, Oncogene Proteins, Fusion genetics, Phosphorylation, Proto-Oncogene Proteins c-bcl-2 genetics, Transcription Factors genetics, Apoptosis, Caenorhabditis elegans Proteins, Cyclic AMP Response Element-Binding Protein physiology, DNA-Binding Proteins metabolism, Helminth Proteins metabolism, Interleukin-3 metabolism, Leucine Zippers, Oncogene Proteins, Fusion metabolism, Signal Transduction, Transcription Factors metabolism
Abstract

The Ces-2/E2A-HLF binding element (CBE) is recognized by Caenorhabditis elegans death specification gene product Ces-2 and human acute lymphocytic leukemia oncoprotein E2A-HLF. In an attempt to identify a cellular CBE-binding protein(s) that may be involved in apoptosis regulation in mammals, multiple nuclear binding complexes of CBE were identified in various mammalian cell lines and tissues by electrophoretic mobility shift assay. Cyclic AMP (cAMP)-responsive element (CRE)-binding protein (CREB) was present in one major CBE complex of Ba/F3 and TF-1 cells, and both in vitro-translated and Escherichia coli-synthesized CREB bound to CBE. Activation of CREB by cAMP-elevating chemicals or the catalytic subunit of protein kinase A (PKAc) resulted in induction of the CBE-driven reporter gene. Stimulation of Ba/F3 cells with interleukin-3 (IL-3) promptly induced phosphorylation of CREB at serine(133) partially via a PKA-dependent pathway. Consistently, Ba/F3 cell survival in the absence of IL-3 was prolonged by activation of PKA. Conversely, treatment of cells with a PKA inhibitor or expression of the dominant negative forms of the regulatory subunit type I of PKA and CREB overrode the survival activity of IL-3. Last, the bcl-2 gene was demonstrated to be one candidate cellular target of the CREB-containing CBE complex, as mutations in the CRE and CBE sites significantly reduced the IL-3 inducibility of the bcl-2 promoter. Together, our results suggest that CREB is one cellular counterpart of Ces-2/E2A-HLF and is part of IL-3 dependent apoptosis regulation in hematopoietic cells.

Published
2001
Full Text
View/download PDF

40. Mcl-1 is a common target of stem cell factor and interleukin-5 for apoptosis prevention activity via MEK/MAPK and PI-3K/Akt pathways.

Author

Huang HM, Huang CJ, and Yen JJ

Subjects
Blotting, Western, Cell Survival drug effects, Chromones pharmacology, Cytokines pharmacology, Enzyme Inhibitors pharmacology, Flavonoids pharmacology, Granulocyte-Macrophage Colony-Stimulating Factor pharmacology, Humans, MAP Kinase Signaling System drug effects, Mitogen-Activated Protein Kinases antagonists & inhibitors, Mitogen-Activated Protein Kinases metabolism, Morpholines pharmacology, Myeloid Cell Leukemia Sequence 1 Protein, Neoplasm Proteins metabolism, Phosphatidylinositol 3-Kinases metabolism, Phosphoinositide-3 Kinase Inhibitors, Proto-Oncogene Proteins metabolism, Proto-Oncogene Proteins c-akt, Tumor Cells, Cultured, Apoptosis drug effects, Interleukin-5 pharmacology, Neoplasm Proteins drug effects, Phosphotransferases metabolism, Protein Serine-Threonine Kinases, Proto-Oncogene Proteins c-bcl-2, Signal Transduction drug effects, Stem Cell Factor pharmacology
Abstract

Stem cell factor (SCF) has been suggested as essential for optimal production of various hematopoietic lineages mainly because of its apoptosis prevention function when it costimulates with other cytokines. However, the underlying mechanism of this synergism of apoptosis prevention is largely unknown. The present study examined the expression of some Bcl-2 family members, including Bcl-2, Bcl-X(L), Mcl-1, and Bax, in response to cytokine stimulation in TF-1 and JYTF-1 cells in which SCF costimulation is differentially required for optimal proliferation. The results revealed that only the expression of Mcl-1 highly correlated with the antiapoptotic activity of interleukin-5 (IL-5) and the synergistic effect of SCF. In TF-1 cells, the defect of IL-5 in apoptosis suppression and Mcl-1 induction was associated with the incapability to highly phosphorylate Janus kinases (JAK1, JAK2), signal transducer and activator of transcription-5 (STAT5), mitogen-activated protein kinase (MAPK), and Akt/PKB, whereas SCF costimulation restored the potent phosphorylation of MAPK and Akt/PKB, but not STAT5. The importance of MAPK and Akt/PKB signaling pathways in regulating the expression of Mcl-1 and cell survival was further supported by the observation that inhibition of MEK by PD98059 or phosphatidylinositol-3 kinase (PI-3K) by LY294002 independently resulted in the reduction of Mcl-1 expression and loss of cell viability. Therefore, the data suggest that Mcl-1 is a common antiapoptotic target of both early-stage cytokine SCF and late-stage cytokine IL-5. Both MEK/MAPK and PI-3K/Akt signaling pathways are essential in the regulation of Mcl-1 expression and apoptosis prevention. (Blood. 2000;96:1764-1771)

Published
2000

41. Coupling of osteopontin and its cell surface receptor CD44 to the cell survival response elicited by interleukin-3 or granulocyte-macrophage colony-stimulating factor.

Author

Lin YH, Huang CJ, Chao JR, Chen ST, Lee SF, Yen JJ, and Yang-Yen HF

Subjects
Animals, CHO Cells, Cell Survival drug effects, Cell Survival physiology, Cricetinae, Humans, Mice, Osteopontin, Signal Transduction drug effects, Granulocyte-Macrophage Colony-Stimulating Factor pharmacology, Hyaluronan Receptors physiology, Interleukin-3 pharmacology, Sialoglycoproteins physiology, Signal Transduction physiology
Abstract

The receptors for interleukin-3 (IL-3) and granulocyte-macrophage colony-stimulating factor (GM-CSF) share a common beta subunit, the distal cytoplasmic domain of which is essential for the promotion of cell survival by these two cytokines. Genes whose expression is specifically induced by signaling through the distal cytoplasmic domain of this receptor beta subunit were screened by a subtraction cloning approach in derivatives of a mouse pro-B-cell line. One gene thus identified was shown to encode a protein highly homologous (with only 7 amino acid substitutions) to murine osteopontin (OPN), a secreted adhesion protein. Conditioned medium from cells expressing wild-type OPN, but not that from cells expressing a deletion mutant lacking residues 79 to 140, increased the viability of a non-OPN-producing cell line in the presence of human GM-CSF. Antibody blocking experiments revealed that OPN produced as a result of IL-3 or GM-CSF signaling was secreted into the medium and, through binding to its cell surface receptor, CD44, contributed to the survival-promoting activities of these two cytokines. Furthermore, coupling of the OPN-CD44 pathway to the survival response to IL-3 was also demonstrated in primary IL-3-dependent mouse bone marrow cells. These results thus show that induction of an extracellular adhesion protein and consequent activation of its cell surface receptor are important for the antiapoptotic activities of IL-3 and GM-CSF.

Published
2000
Full Text
View/download PDF

42. Optimal proliferation of a hematopoietic progenitor cell line requires either costimulation with stem cell factor or increase of receptor expression that can be replaced by overexpression of Bcl-2.

Author

Huang HM, Li JC, Hsieh YC, Yang-Yen HF, and Yen JJ

Subjects
Cell Differentiation, Cell Division drug effects, Cell Division physiology, Cell Line, Cell Survival drug effects, Cell Survival physiology, Flow Cytometry, Granulocyte-Macrophage Colony-Stimulating Factor pharmacology, Granulocyte-Macrophage Colony-Stimulating Factor physiology, Hematopoietic Stem Cells drug effects, Humans, Interleukin-5 pharmacology, Kinetics, Proto-Oncogene Proteins c-bcl-2 physiology, Recombinant Proteins metabolism, Recombinant Proteins pharmacology, Stem Cell Factor physiology, Transfection, Hematopoietic Stem Cells cytology, Hematopoietic Stem Cells physiology, Proto-Oncogene Proteins c-bcl-2 genetics, Proto-Oncogene Proteins c-kit physiology, Stem Cell Factor pharmacology
Abstract

In vitro proliferation of hematopoietic stem cells requires costimulation by multiple regulatory factors whereas expansion of lineage-committed progenitor cells generated by stem cells usually requires only a single factor. The distinct requirement of factors for proliferation coincides with the differential temporal expression of the subunits of cytokine receptors during early stem cell differentiation. In this study, we explored the underlying mechanism of the requirement of costimulation in a hematopoietic progenitor cell line TF-1. We found that granulocyte-macrophage colony-stimulating factor (GM-CSF) optimally activated proliferation of TF-1 cells regardless of the presence or absence of stem cell factor (SCF). However, interleukin-5 (IL-5) alone sustained survival of TF-1 cells and required costimulation of SCF for optimal proliferation. The synergistic effect of SCF was partly due to its anti-apoptosis activity. Overexpression of the IL-5 receptor alpha subunit (IL5Ralpha) in TF-1 cells by genetic selection or retroviral infection also resumed optimal proliferation due to correction of the defect in apoptosis suppression. Exogenous expression of an oncogenic anti-apoptosis protein, Bcl-2, conferred on TF-1 cells an IL-5-dependent phenotype. In summary, our data suggested SCF costimulation is only necessary when the expression level of IL5Ralpha is low and apoptosis suppression is defective in the signal transduction of IL-5. Expression of Bcl-2 proteins released the growth restriction of the progenitor cells and may be implicated in leukemia formation.

Published
1999

43. Characterization of factor-independent variants derived from TF-1 hematopoietic progenitor cells: the role of the Raf/MAP kinase pathway in the anti-apoptotic effect of GM-CSF.

Author

Chao JR, Chen CS, Wang TF, Tseng LH, Tsai JJ, Kuo ML, Yen JJ, and Yang Yen HF

Subjects
Apoptosis physiology, Calcium-Calmodulin-Dependent Protein Kinases metabolism, Cell Division drug effects, Cell Division physiology, Cells, Cultured, Enzyme Activation, Granulocyte-Macrophage Colony-Stimulating Factor deficiency, Granulocyte-Macrophage Colony-Stimulating Factor physiology, Hematopoietic Stem Cells physiology, Humans, Interleukin-3 deficiency, Interleukin-3 pharmacology, Interleukin-3 physiology, Protein Serine-Threonine Kinases metabolism, Proto-Oncogene Proteins metabolism, Proto-Oncogene Proteins c-raf, Apoptosis drug effects, Calcium-Calmodulin-Dependent Protein Kinases physiology, Granulocyte-Macrophage Colony-Stimulating Factor pharmacology, Hematopoietic Stem Cells cytology, Hematopoietic Stem Cells drug effects, Protein Serine-Threonine Kinases physiology, Proto-Oncogene Proteins physiology, Signal Transduction physiology
Abstract

Human hematopoietic progenitor cells (TF-1) undergo apoptosis upon deprivation of their dependent cytokine. In this report, we have isolated and characterized some spontaneously derived cytokine-independent variants from TF-1 cells. Analysis of several signaling molecules known to be activated by the GM-CSF pathway revealed that two non-autocrine variants were still responsive to GM-CSF stimulation. However, both variants, without ligand stimulation, already had some activated forms of Raf and MAP kinases. Given current knowledge, the activated Raf/MAP kinase pathway was likely to be responsible for the survival of both variants in the cytokine-free medium. However, the growth of hybrids between wild type and either variant was unexpectedly dependent on GM-CSF. Both variants like the wild type cells were still susceptible to apoptosis induced by other stimuli. These results suggest that either the activated Raf/MAP kinase pathway in both variants is not sufficient to repress the 'two-fold' death signals generated from the hybrids or that there is another mechanism that is responsible for the factor-independent growth of both variants.

Published
1997
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results