20 results on '"Yu, Yi-Chien"'
Search Results
2. Is achieving 7,000 steps/day cross-sectionally and prospectively associated with older adults’ lower-extremity performance?
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Hsueh, Ming-Chun, Lin, Chien-Yu, Lai, Ting-Fu, Yu, Yi-Chien, Chang, Shao-Hsi, Bae, Ju Yong, and Liao, Yung
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- 2021
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3. Case Report: Plasma Biomarkers Reflect Immune Mechanisms of Guillain–Barré Syndrome
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Chia-Lun Wu, Chung-Hao Chao, Shun-Wen Lin, Yu-Yi Chien, Wen-Yi Huang, Wei-Chieh Weng, Feng-Chieh Su, and Yi-Chia Wei
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Guillain–Barré syndrome ,cytokine ,blood biomarker ,Luminex ,bead-based multiplexing immuno assay ,immune mechanism ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
This case series reported a group of patients with Guillain–Barré syndrome (GBS) and their plasma cytokine changes before and after immunotherapy. We aimed to understand GBS's pathogenesis and pathophysiology through observing the interval differences of the representative cytokines, which were the thymus and activation regulated chemokine (TARC) for T-cell chemotaxis, CD40 ligand (CD40L) for cosimulation of B and T cells, activated complement component C5/C5a, and brain-derived neurotrophic factor (BDNF) for survival and regenerative responses to nerve injuries. The fluorescence magnetic bead-based multiplexing immunoassay simultaneously quantified the five cytokines in a single sample. From June 2018 to December 2019, we enrolled five GBS patients who had completed before–after blood cytokine measurements. One patient was diagnosed with paraneoplastic GBS and excluded from the following cytokine analysis. The BDNF level decreased consistently in all the patients and made it a potential biomarker for the acute stage of GBS. Interval changes of the other four cytokines were relatively inconsistent and possibly related to interindividual differences in the immune response to GBS triggers, types of GBS variants, and classes of antiganglioside antibodies. In summary, utilizing the multiplexing immunoassay helps in understanding the complex immune mechanisms of GBS and the variation of immune responses in GBS subtypes; this method is feasible for identifying potential biomarkers of GBS.
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- 2021
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4. Lipid Paradox in Statin-Naïve Acute Ischemic Stroke But Not Hemorrhagic Stroke
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Kai-Hung Cheng, Jr-Rung Lin, Craig S. Anderson, Wen-Ter Lai, Tsong-Hai Lee, the SRICHS Group, Yeu-Jhy Chang, Chien-Hung Chang, Hsiu-Chuan Wu, Kuo-Lun Huang, Ting-Yu Chang, Chi-Hung Liu, Chih-Kuang Cheng, Te-Fa Chiu, Chi-Ren Huang, Ho-Fai Wong, Cheng-Hong Toh, Tsung-I Peng, Wen-Yi Huang, Yu-Yi Chien, Kong Chung, Hsiang-Yun Lo, Yao-Liang Chen, Jiann-Der Lee, Meng Lee, Yen-Chu Huang, Shao-Wen Chou, Cheng-Ting Hsiao, Yuan-Hsiung Tsai, Chia-Wei Liou, Ku-Chou Chang, Hung-Sheng Lin, Teng-Yeow Tan, Ru-Huei Fu, Wei Hsi Chen, Chia-Te Kung, and Wei-Che Lin
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ischemic stroke ,intracerebral hemorrhage ,lipids ,mortality ,stroke outcome ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Background: Low lipid level is associated with better cardiovascular outcome. However, lipid paradox indicating low lipid level having worse outcomes could be seen under acute injury in some diseases. The present study was designed to clarify the prognostic significance of acute-phase lipid levels within 1 day after admission for stroke on mortality in first-ever statin-naïve acute ischemic stroke (IS) and hemorrhagic stroke (HS).Methods: This observational study was conducted using the data collected from Stroke Registry In Chang-Gung Healthcare System (SRICHS) between 2009 and 2012. Patients with recurrent stroke, onset of symptoms >1 day, and history of the use of lipid-lowering agents prior to index stroke were excluded. Stroke was classified into IS and hypertension-related HS. The primary outcomes were 30-day and 1-year mortality identified by linkage to national death registry for date and cause of death. Receiver operating characteristic (ROC) curve analysis and multivariate Cox proportional hazard models were used to examine the association of lipid profiles on admission with mortality.Results: Among the 18,268 admitted stroke patients, 3,746 IS and 465 HS patients were eligible for analysis. In IS, total cholesterol (TC)
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- 2018
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5. Oculopharyngeal muscular dystrophy – An under-diagnosed disease in China? Report a China-born Chinese with PABPN1 mutation and epidemiology review of the literature
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Yu-Yi Chien
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epidemiology ,filamentous inclusions ,oculopharyngeal muscular dystrophy ,polyadenylate binding protein nuclear 1 gene ,prevalence ,rimmed-vacuole ,Medicine (General) ,R5-920 - Abstract
Most reports about oculopharyngeal muscular dystrophy (OPMD) have been contributed by occidental countries, and most of the victims of this disease are racially white. In contrast, this disorder is rarely seen in Asians and has only one African report. Consequently, OPMD has been regarded as a disease of the Western world. The purpose of this paper is to challenge the accuracy of this concept. Methods: In a Chinese immigrant family, 3 patients manifesting signs related to OPMD were examined. Electromyography, nerve conduction studies, muscle biopsy and genetic analysis were performed on the proband. All the 322 papers about OPMD were reviewed and their country of origin was labeled to perceive the approximate prevalence of OPMD. Countries were categorized into groups according to the continents to which they belonged. Results: The proband's muscle histopathology showed small angulated fiber with rimmed vacuoles, ultrastructural pathology exposed filamentous intranuclear inclusions, and genetic analysis of the polyadenylate binding protein nuclear 1(PABPN1) gene revealed 13 GCG trinucleotide repeats in one allele (GCG)13 while being normal in the other. The survey of the country of origin of OPMD reports showed that 80% of these papers were contributed by occidental countries and that the number of publications of OPMD among countries of Americas and Asia were unequal, when compared to those of European countries, which were fairly proportioned. An epidemiologic review of the literature is presented and the prevalence of OPMD is discussed. Conclusion: This is a China-born Chinese patient with both morphologically and genetically proven of OPMD. The very low OPMD report rate in developing countries of East Asia is due to the unfamiliarity of medical workers to OPMD and the unavailability of medical supplies to confirm the diagnosis. In addition, the present and previous reports provide clear evidence that OPMD in these areas is underdiagnosed.
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- 2012
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6. Clinical characteristics of adult tetanus in a Taiwan medical center
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Wei-Chieh Weng, Wen-Yi Huang, Tsung-I. Peng, Yu-Yi Chien, Kuo-Hsuan Chang, Long-Sun Ro, Rong-Kuo Lyu, and Chia-Lun Wu
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immunization ,respiratory failure ,tetanus ,Medicine (General) ,R5-920 - Abstract
Despite effective vaccine programs, tetanus is occasionally observed in adults. We reviewed clinical presentation data for adult patients with tetanus in the post-vaccine era in Taiwan. Methods: We retrospectively reviewed the medical records of all adult patients (age >18 years) discharged from Chang-Gung Memorial Hospital at Lin-Ko (CGMHLK) after treatment for tetanus between January 1996 and July 2005. Data regarding demographic characteristics, clinical manifestation, treatment, and outcome were collected. To assess the features for different age groups, patients were divided into those aged ≥65 years and those aged
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- 2011
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7. Additional file 1 of Is functional fitness performance a useful predictor of risk of falls among community-dwelling older adults?
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Ho, Hsin-Hung, Fang, I-Yao, Yu, Yi-Chien, Huang, Yi-Ping, Kuo, I-Ling, Wang, Li-Ting, Tsai, Ming-Chueh, Chang, Shao-Hsi, and Hsueh, Ming-Chun
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Data_FILES - Abstract
Additional file 1.
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- 2021
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8. Neighborhood Environment and Objectively Measured Sedentary Behavior Among Older Adults: A Cross-Sectional Study
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Chang, Shao-Hsi, primary, Rutherford, Ru, additional, Hsueh, Ming-Chun, additional, Yu, Yi-Chien, additional, Park, Jong-Hwan, additional, Wang, Sendo, additional, and Liao, Yung, additional
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- 2021
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9. Detecting Glaucoma With a Portable Brain-Computer Interface for Objective Assessment of Visual Function Loss
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Fábio B. Daga, Yijun Wang, Yu-Te Wang, Felipe A. Medeiros, Alberto Diniz-Filho, Tzyy-Ping Jung, Masaki Nakanishi, John K. Zao, Yu-Yi Chien, and Yuan-Pin Lin
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Male ,medicine.medical_specialty ,Intraocular pressure ,genetic structures ,Intraclass correlation ,Glaucoma ,Audiology ,Electroencephalography ,Blindness ,Ophthalmology & Optometry ,Article ,03 medical and health sciences ,0302 clinical medicine ,Optics ,Opthalmology and Optometry ,medicine ,Humans ,Prospective Studies ,Evoked Potentials ,Intraocular Pressure ,Aged ,Receiver operating characteristic ,medicine.diagnostic_test ,business.industry ,Repeatability ,Equipment Design ,medicine.disease ,eye diseases ,Visual field ,Ophthalmology ,medicine.anatomical_structure ,ROC Curve ,Brain-Computer Interfaces ,030221 ophthalmology & optometry ,Evoked Potentials, Visual ,Female ,Visual Fields ,business ,Visual ,030217 neurology & neurosurgery ,Optic disc ,Follow-Up Studies - Abstract
Importance The current assessment of visual field loss in diseases such as glaucoma is affected by the subjectivity of patient responses and the lack of portability of standard perimeters. Objective To describe the development and initial validation of a portable brain-computer interface (BCI) for objectively assessing visual function loss. Design, Setting, and Participants This case-control study involved 62 eyes of 33 patients with glaucoma and 30 eyes of 17 healthy participants. Glaucoma was diagnosed based on a masked grading of optic disc stereophotographs. All participants underwent testing with a BCI device and standard automated perimetry (SAP) within 3 months. The BCI device integrates wearable, wireless, dry electroencephalogram and electrooculogram systems and a cellphone-based head-mounted display to enable the detection of multifocal steady state visual-evoked potentials associated with visual field stimulation. The performances of global and sectoral multifocal steady state visual-evoked potentials metrics to discriminate glaucomatous from healthy eyes were compared with global and sectoral SAP parameters. The repeatability of the BCI device measurements was assessed by collecting results of repeated testing in 20 eyes of 10 participants with glaucoma for 3 sessions of measurements separated by weekly intervals. Main Outcomes and Measures Receiver operating characteristic curves summarizing diagnostic accuracy. Intraclass correlation coefficients and coefficients of variation for assessing repeatability. Results Among the 33 participants with glaucoma, 19 (58%) were white, 12 (36%) were black, and 2 (6%) were Asian, while among the 17 participants with healthy eyes, 9 (53%) were white, 8 (47%) were black, and none were Asian. The receiver operating characteristic curve area for the global BCI multifocal steady state visual-evoked potentials parameter was 0.92 (95% CI, 0.86-0.96), which was larger than for SAP mean deviation (area under the curve, 0.81; 95% CI, 0.72-0.90), SAP mean sensitivity (area under the curve, 0.80; 95% CI, 0.69-0.88; P = .03), and SAP pattern standard deviation (area under the curve, 0.77; 95% CI, 0.66-0.87; P = .01). No statistically significant differences were seen for the sectoral measurements between the BCI and SAP. Intraclass coefficients for global and sectoral parameters ranged from 0.74 to 0.92, and mean coefficients of variation ranged from 3.03% to 7.45%. Conclusions and Relevance The BCI device may be useful for assessing the electrical brain responses associated with visual field stimulation. The device discriminated eyes with glaucomatous neuropathy from healthy eyes in a clinically based setting. Further studies should investigate the feasibility of the BCI device for home-based testing as well as for detecting visual function loss over time.
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- 2017
10. Polychromatic SSVEP stimuli with subtle flickering adapted to brain-display interactions
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Yi-Pai Huang, Heng Yuan Kuo, Yijun Wang, Fang-Cheng Lin, John K. Zao, Ching Chi Chou, Tzyy-Ping Jung, Yu Yi Chien, and Han-Ping D. Shieh
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Adult ,Male ,Visual perception ,Photic Stimulation ,Color vision ,0206 medical engineering ,Clinical Sciences ,Biomedical Engineering ,Color ,02 engineering and technology ,Flicker fusion threshold ,Stimulus (physiology) ,Luminance ,Flicker Fusion ,03 medical and health sciences ,Cellular and Molecular Neuroscience ,User-Computer Interface ,0302 clinical medicine ,steady-state visual evoked ,Humans ,Computer vision ,Evoked Potentials ,Brain–computer interface ,canonical correlation analysis ,Color Vision ,business.industry ,Flicker ,brain-computer interface ,Neurosciences ,020601 biomedical engineering ,subtle flickering ,potentials ,Brain-Computer Interfaces ,Evoked Potentials, Visual ,Female ,visual stimuli ,Artificial intelligence ,polychromatic ,business ,Psychology ,Visual ,030217 neurology & neurosurgery ,interactive display systems - Abstract
Author(s): Chien, Yu-Yi; Lin, Fang-Cheng; Zao, John K; Chou, Ching-Chi; Huang, Yi-Pai; Kuo, Heng-Yuan; Wang, Yijun; Jung, Tzyy-Ping; Shieh, Han-Ping D | Abstract: ObjectiveInteractive displays armed with natural user interfaces (NUIs) will likely lead the next breakthrough in consumer electronics, and brain-computer interfaces (BCIs) are often regarded as the ultimate NUI-enabling machines to respond to human emotions and mental states. Steady-state visual evoked potentials (SSVEPs) are a commonly used BCI modality due to the ease of detection and high information transfer rates. However, the presence of flickering stimuli may cause user discomfort and can even induce migraines and seizures. With the aim of designing visual stimuli that can be embedded into video images, this study developed a novel approach to induce detectable SSVEPs using a composition of red/green/blue flickering lights.ApproachBased on the opponent theory of colour vision, this study used 32 Hz/40 Hz rectangular red-green or red-blue LED light pulses with a 50% duty cycle, balanced/equal luminance and 0°/180° phase shifts as the stimulating light sources and tested their efficacy in producing SSVEP responses with high signal-to-noise ratios (SNRs) while reducing the perceived flickering sensation.Main resultsThe empirical results from ten healthy subjects showed that dual-colour lights flickering at 32 Hz/40 Hz with a 50% duty cycle and 180° phase shift achieved a greater than 90% detection accuracy with little or no flickering sensation.SignificanceAs a first step in developing an embedded SSVEP stimulus in commercial displays, this study provides a foundation for developing a combination of three primary colour flickering backlights with adjustable luminance proportions to create a subtle flickering polychromatic light that can elicit SSVEPs at the basic flickering frequency.
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- 2017
11. Autosomal dominant Late-onset Quadriceps Myopathy: Three Patients of a Taiwanese Kindred
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Daryi Wang, Yu-Yi Chien, and Ikuya Nonaka
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Male ,medicine.medical_specialty ,Pathology ,Biopsy ,Taiwan ,Late onset ,Electromyography ,Quadriceps Muscle ,Atrophy ,Muscular Diseases ,Internal Medicine ,medicine ,Humans ,Myopathy ,Anterior compartment of thigh ,Aged ,Muscle Weakness ,medicine.diagnostic_test ,business.industry ,Age Factors ,General Medicine ,Anatomy ,Middle Aged ,medicine.disease ,Pedigree ,Muscular Atrophy ,Etiology ,Female ,Histopathology ,medicine.symptom ,Tomography, X-Ray Computed ,business - Abstract
Objective Primary quadriceps weakness/atrophy is a rare disorder with variable etiologies; therefore, this disorder has been regarded as a clinical syndrome rather than a distinct entity. However, three affected patients of a Taiwanese family demonstrate a uniform pattern of quadriceps weakness and atrophy, their clinical manifestations and pattern of inheritance may suggest a new disease entity. Patients and Methods Three patients in a Taiwanese kindred with selective quadriceps weakness and atrophy, which began after age 40 years, were examined. To disclose the confines of this disorder, muscle CT scans, electromyography, nerve conduction studies and muscle biopsies were performed; and to unravel and better understand the nature of this disorder, histopathological, ultrastructural, immunocytochemical and genetic studies were carried out. Results In two patients with long-standing disease, muscle imaging showed marked atrophy and fat replacement of the anterior thigh muscles and electromyography showed a mixture of myopathic and neuropathic changes. Muscle histopathology on the mildly affected tibialis anterior showed myopathic changes with myofibrillar degeneration and secondary neurogenic alterations. Immunocytochemical staining was not diagnostic but excluded the dystrophinopathies and other well-known muscular dystrophies. Conclusion All previously identified diseases resulting in quadriceps weakness and atrophy have been ruled out and the present disorder appears to be a new disease entity of autosomal dominant late onset quadriceps myopathy.
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- 2011
12. Contents Vol. 20, 2000
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Takashi Shigematsu, Sergio Zabala, Marta Beciani, Sophie Lantsberg, Tiziana Tullio, Yeu-Jun Lau, Fu Keung Li, Paul Khoury, Takanori Maruyama, Yancu Hertzanu, Feng-Chun Tsai, Juán J. Bélvis, Mira Choi, Robert Chvala, Shiro Goto, Ursula Göbel, Leonid Feldman, Andrew K. Watters, Mariko Uehara, Yasutaka Kajita, Ning Lee, Moshe Zlotnik, Jong-Da Lian, Dario Zazzaro, Antonio Gascón, Kuo-Su Chen, Emilia Iglesias, David Tovbin, Anna Basok, Giorgio Coen, Emanuela D’Anello, Mayumi Hamada, Bor-Shen Hu, Christos M. Tsoukas, Cheng-Hsu Chen, Alla Shnaider, Daniela Mantella, Ka Neng Lai, Daniela Sardella, Roberto Colombo, Micaela Manni, Junko Odachi, Kazuharu Suzuki, Chi-Hung Cheng, Yukitaka Maruyama, G. Splendiani, Angela Dinnella, Alexander Woywodt, Akira Hishida, Wolfgang Schneider, Akihiko Kato, Anneo Violante, Yu-Yi Chien, James T. McCarthy, Cynthia E. Regnier, Ming-Ju Wu, Raymonde F. Gagnon, Kuo-Hsiung Shu, Erik J. Bergstralh, Tak Mao Chan, George E. Hatzakis, Ralph Kettritz, Antonio Sturniolo, Santo Calabria, Sandy N. Tecimer, Chien-Hung Lee, Bulent Cuhaci, Horng-Rong Chang, Ritsuko Masuyama, Carrie L. Loebertmann, and Markus Mostoslavsky
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Traditional medicine ,Nephrology ,business.industry ,Medicine ,business - Published
- 2000
13. Fiber Type Profile Change after Partial and Total Denervation in Rat. Soleus Muscles
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Yu-Yi Chien and Nai-Shin Chu
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Denervation ,Soleus muscle ,medicine.medical_specialty ,Histology ,Fiber type ,biology ,Physiology ,Chemistry ,ATPase ,Cell Biology ,Anatomy ,Biochemistry ,Pathology and Forensic Medicine ,Endocrinology ,Partial denervation ,Internal medicine ,biology.protein ,medicine ,Fiber ,Myofibril ,Nerve resection - Abstract
The short-term effects after experimental partial and total denervation on histochemical fiber type profiles were studied in rat soleus muscles by the myofibrillar ATPase stain. In 58 control soleus muscles, a total of 155788 fibers were counted, comprising type 1 (75.1%), type 2A (13.3%), type 2B (1.4%) and type 2C (10.3%), respectively. In 34 animals with total denervation, including 17 with soleus nerve resection at 1cm before entering the soleus muscle and 17 with total sciatic neurectomy, the proportion of type 1 fiber was decreased in denervated muscles to 39.1% 5 weeks after the procedures. In parallel with a decrease in type 1 fiber proportion, undifferentiated type 2C fibers increased, thereby suggesting muscle fiber type dedifferentiation taking place in totally denervated muscle. In contrast, 24 muscles with partial denervation showed a decreased proportion of type 1 fibers at the initial stage followed by an increase in type 1 fiber to 89.0% 5 weeks after denervation, resulting from an active reinnervating process.
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- 1995
14. Effects of Partial and Total Denervation on the Distribution of Fiber Size of Rat Soleus Muscles: A Quantitative Computer Imaging Analysis
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Nai-Shin Chu and Yu-Yi Chien
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Denervation ,Soleus muscle ,Histology ,Physiology ,Chemistry ,Fiber size ,Cell Biology ,Anatomy ,Muscle mass ,Biochemistry ,Pathology and Forensic Medicine ,Partial denervation ,Distribution (pharmacology) ,Fiber ,Computer imaging - Abstract
The effects of partial and total denervation on muscle fibers were studied in rat soleus muscles by quantitative computer imaging analysis. Within 5 weeks after denervation, there was a progressive reduction of the soleus muscle weight in total denervation groups but a gradual recovery beginning in the third week and reaching 75% of the control in the fifth week in the partial denervation group. The reduction of muscle mass was mainly due to the replacement of large and medium-sized fibers by small atrophic fibers.In totally denervated muscles, cross-sectional fiber area showed a rapid decline after denervation, but the shape of fiber size distribution was nearly normal. On the other hand, partially denervated muscles showed an asymmetrical fiber size distribution with a shift toward large fibers. In control and totally denervated muscles, mean fiber area strongly correlated with the standard deviation from the mean, but in partially denervated muscles, this strong correlation no longer existed and was replaced by larger standard deviations. It is concluded that only partially denervated muscles show significant variations in fiber size.
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- 1995
15. Sharp Wave Based HHT Time-frequency Features with Transmission Error
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Bing-Han Yang, Chin-Feng Lin, Shun-Hsyung Chang, Jung-Hua Wang, Yu-Yi Chien, and Tsung-Ii Peng
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Signal processing ,business.industry ,Acoustics ,Wavelet transform ,Pattern recognition ,Gabor transform ,Hilbert spectral analysis ,Hilbert–Huang transform ,Time–frequency analysis ,symbols.namesake ,Fourier transform ,Electrocardiographs ,symbols ,Artificial intelligence ,business ,Mathematics - Abstract
Signal analysis is a field of study that attempts to extract information features from various physical phenomena. Fourier transform (FT), wavelet transform (WT), and Hilbert-Huang transformation (HHT) are the 3 major approaches used in signal analysis (Huang et al., 1998) (Yan & Gao, 2007). FT is a global energy-frequency distribution approach that is suitable for analyzing linear, strictly periodic, and stationary signals. In contrast, HHT is a good method for analyzing non-linear and non-stationary signals, such as those associated with wind, earthquakes, electrocardiographs (ECGs), and electroencephalograms (EEGs). This method can also used to describe the local features of dynamic signals, and illustrate the energy-frequency-time distribution of these signals. The 2 principal steps employed in HHT are empirical mode decomposition (EMD) and Hilbert spectral analysis, EMD is used to decompose local signals to finite data sets, which are referred to as intrinsic mode functions (IMFs), and Hilbert transforms (HTs) are used in conjunction with the obtained IMFs to determine the instantaneous frequencies (IFs), time-frequency-energy distributions of the local time signals. A number of studies have been performed to elucidate various aspects of signal analysis. Cohen reviewed the fundamental ideas, methods, and characteristics of the time-frequency analysis approaches employed until 1989 (Cohen, 1989). Blanco et al., used the Gabor transform (GT) time-frequency analysis approach to facilitate identification of the source of epileptic seizures (Blanco et al., 1997). The GT approach is similar to the fast FT approach, but GT offers the advantage of allowing the analysis of the frequencies and their time evolution. Blanco et al., adopted GT to achieve maximal concentration of the time and frequency characteristics for epilepsy and obtain accurate information on the time evolution of the frequency epileptic activity. Tzallas et al., used short-time Fourier transform and 12 different time-frequency distributions for studying epilepsy classification problems and discussed the obtained sensitivity, accuracy, and selectivity results, and the characteristic data features for the detection of epilepsy (Tzallas et al., 2009). However, they did not use the HHT-based time-frequency analysis approach to define epileptic sharps. Sharabaty et al., used the HHT signal-analysis approach to determine the alpha and theta localizations for estimation of the vigilance level, and
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- 2011
16. Subject Index Vol. 20, 2000
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Anna Basok, Emilia Iglesias, Micaela Manni, Anneo Violante, Angela Dinnella, Fu Keung Li, Giorgio Coen, Leonid Feldman, Yasutaka Kajita, Ning Lee, Sandy N. Tecimer, Yukitaka Maruyama, Antonio Sturniolo, Yeu-Jun Lau, Ka Neng Lai, Daniela Sardella, Dario Zazzaro, Bulent Cuhaci, Takashi Shigematsu, Feng-Chun Tsai, Christos M. Tsoukas, Ritsuko Masuyama, Wolfgang Schneider, Santo Calabria, Mariko Uehara, Horng-Rong Chang, Moshe Zlotnik, Jong-Da Lian, Roberto Colombo, Mira Choi, Giorgio Splendiani, Erik J. Bergstralh, Juán J. Bélvis, Tak Mao Chan, Cynthia E. Regnier, David Tovbin, Cheng-Hsu Chen, Emanuela D’Anello, James T. McCarthy, Yancu Hertzanu, Bor-Shen Hu, Chi-Hung Cheng, Chien-Hung Lee, Ming-Ju Wu, Ralph Kettritz, Alla Shnaider, Antonio Gascón, Raymonde F. Gagnon, Takanori Maruyama, Akihiko Kato, Yu-Yi Chien, Shiro Goto, Robert Chvala, Ursula Göbel, Kuo-Hsiung Shu, Daniela Mantella, Marta Beciani, Paul Khoury, Tiziana Tullio, George E. Hatzakis, Andrew K. Watters, Carrie L. Loebertmann, Kuo-Su Chen, Markus Mostoslavsky, Mayumi Hamada, Sergio Zabala, Sophie Lantsberg, Akira Hishida, Kazuharu Suzuki, Alexander Woywodt, and Junko Odachi
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Gerontology ,Index (economics) ,Nephrology ,business.industry ,Medicine ,Subject (documents) ,business - Published
- 2000
17. Predictive factors of outcome and stroke recurrence in patients with unilateral atherosclerosis-related internal carotid artery occlusion
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Kuan-Hsing Chen, Wen-Yi Huang, Chia-Lun Wu, Tsung-I Peng, Yu-Yi Chien, and Wei-Chieh Weng
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Carotid Artery Diseases ,Male ,medicine.medical_specialty ,Anemia ,Functional Laterality ,Predictive Value of Tests ,Recurrence ,Risk Factors ,Internal medicine ,medicine.artery ,Occlusion ,medicine ,Humans ,cardiovascular diseases ,Prospective Studies ,Prospective cohort study ,Stroke ,Survival analysis ,Aged ,Chi-Square Distribution ,business.industry ,Middle Aged ,medicine.disease ,Intracranial Arteriosclerosis ,Survival Analysis ,Surgery ,Cerebral Angiography ,Treatment Outcome ,Neurology ,Predictive value of tests ,Cardiology ,Female ,Neurology (clinical) ,Internal carotid artery ,business ,Tomography, X-Ray Computed ,Chi-squared distribution - Abstract
Background: Clinical outcome of internal carotid artery (ICA) occlusion is highly variable and the reason is uncertain. Aim: To study the predictive factors of clinical outcome and stroke recurrence in patients with ischemic stroke associated with unilateral atherosclerosis-related ICA occlusion. Settings and Design: Prospective study in neurology department of a single hospital. Materials and Methods: We prospectively studied 66 patients who suffered from first-ever ischemic stroke associated with unilateral atherosclerosis-related ICA occlusion over a period of two years. The end point was death or stroke recurrence. Statistical Analysis: Chi-square or Fisher's exact test was used to analyze predictors of early functional outcome. Multivariate analysis was used to analyze predictors of death or stroke recurrence within two years. Result: Higher age (³70 years) predicted a worse functional outcome ( P = 0.049). Total anterior circulation syndrome (TACS) was associated with a poor functional outcome ( P < 0.001), but lacunar syndrome had a better outcome ( P = 0.001). Stroke in evolution predicted a poor outcome ( P = 0.001), while those with symptom improvement had a better outcome ( P = 0.016). Pneumonia predicted a poor outcome ( P = 0.021). Five patients expired and 22 patients suffered from recurrent stroke in the following 24 months. Previous transient ischemic attack (TIA) and anemia were associated with a higher risk of death or recurrent stroke within two years ( P = 0.036, P = 0.012). Conclusion: High age, TACS, stroke in evolution and pneumonia were predictors for poor functional outcome. Previous TIA and anemia were predictors for death and recurrent stroke within two years.
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- 2008
18. Consultants for the American Journal of Nephrology 2000
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Kuo-Hsiung Shu, Yeu-Jun Lau, Takanori Maruyama, Giorgio Coen, Carrie L. Loebertmann, Chien-Hung Lee, Markus Mostoslavsky, Yancu Hertzanu, Daniela Mantella, Ming-Ju Wu, Raymonde F. Gagnon, Ka Neng Lai, Daniela Sardella, Wolfgang Schneider, Micaela Manni, Antonio Sturniolo, Santo Calabria, Paul Khoury, Bulent Cuhaci, Akira Hishida, Anna Basok, Kazuharu Suzuki, Feng-Chun Tsai, Kuo-Su Chen, Horng-Rong Chang, Alexander Woywodt, Mayumi Hamada, Cheng-Hsu Chen, Ritsuko Masuyama, Tak Mao Chan, Mira Choi, Dario Zazzaro, Alla Shnaider, Roberto Colombo, Akihiko Kato, Yu-Yi Chien, Yukitaka Maruyama, Cynthia E. Regnier, Robert Chvala, Emilia Iglesias, George E. Hatzakis, Ralph Kettritz, Emanuela D’Anello, Anneo Violante, James T. McCarthy, Angela Dinnella, Tiziana Tullio, Christos M. Tsoukas, Fu Keung Li, Junko Odachi, Erik J. Bergstralh, Yasutaka Kajita, David Tovbin, Ning Lee, Sandy N. Tecimer, Shiro Goto, Ursula Göbel, Mariko Uehara, Sergio Zabala, Marta Beciani, Sophie Lantsberg, Andrew K. Watters, Antonio Gascón, G. Splendiani, Juán J. Bélvis, Moshe Zlotnik, Jong-Da Lian, Takashi Shigematsu, Bor-Shen Hu, Chi-Hung Cheng, and Leonid Feldman
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Nephrology ,medicine.medical_specialty ,business.industry ,Family medicine ,Internal medicine ,Medicine ,business - Published
- 2000
19. Predictive factors of outcome and stroke recurrence in patients with unilateral atherosclerosis-related internal carotid artery occlusion.
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Wen-Yi Huang, Wei-Chieh Weng, Yu-Yi Chien, Chia-Lun Wu, Tsung-I Peng, and Kuan-Hsing Chen
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CEREBROVASCULAR disease diagnosis ,ATHEROSCLEROSIS treatment ,CAROTID artery diseases ,LUNG diseases ,CAROTID artery ,CLINICAL medicine - Abstract
Background: Clinical outcome of internal carotid artery (ICA) occlusion is highly variable and the reason is uncertain. Aim: To study the predictive factors of clinical outcome and stroke recurrence in patients with ischemic stroke associated with unilateral atherosclerosis-related ICA occlusion. Settings and Design: Prospective study in neurology department of a single hospital. Materials and Methods: We prospectively studied 66 patients who suffered from first-ever ischemic stroke associated with unilateral atherosclerosis-related ICA occlusion over a period of two years. The end point was death or stroke recurrence. Statistical Analysis: Chi-square or Fisher's exact test was used to analyze predictors of early functional outcome. Multivariate analysis was used to analyze predictors of death or stroke recurrence within two years. Result: Higher age (=70 years) predicted a worse functional outcome (P = 0.049). Total anterior circulation syndrome (TACS) was associated with a poor functional outcome (P < 0.001), but lacunar syndrome had a better outcome (P = 0.001). Stroke in evolution predicted a poor outcome (P = 0.001), while those with symptom improvement had a better outcome (P = 0.016). Pneumonia predicted a poor outcome (P = 0.021). Five patients expired and 22 patients suffered from recurrent stroke in the following 24 months. Previous transient ischemic attack (TIA) and anemia were associated with a higher risk of death or recurrent stroke within two years (P = 0.036, P = 0.012). Conclusion: High age, TACS, stroke in evolution and pneumonia were predictors for poor functional outcome. Previous TIA and anemia were predictors for death and recurrent stroke within two years. [ABSTRACT FROM AUTHOR]
- Published
- 2008
20. Clinical characteristics of adult tetanus in a Taiwan medical center
- Author
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Wen-Yi Huang, Rong-Kuo Lyu, Tsung-I Peng, Wei-Chieh Weng, Long-Sun Ro, Chia-Lun Wu, Yu-Yi Chien, and Kuo-Hsuan Chang
- Subjects
Adult ,Male ,Pediatrics ,medicine.medical_specialty ,Adolescent ,Taiwan ,Disease ,tetanus ,Trismus ,immunization ,Humans ,Medicine ,Aged ,Retrospective Studies ,Aged, 80 and over ,Medicine(all) ,lcsh:R5-920 ,business.industry ,Tetanus ,Incidence ,Medical record ,respiratory failure ,General Medicine ,Middle Aged ,medicine.disease ,Dysphagia ,Surgery ,Pneumonia ,Treatment Outcome ,Respiratory failure ,Female ,medicine.symptom ,business ,Complication ,lcsh:Medicine (General) - Abstract
Background/PurposeDespite effective vaccine programs, tetanus is occasionally observed in adults. We reviewed clinical presentation data for adult patients with tetanus in the post-vaccine era in Taiwan.MethodsWe retrospectively reviewed the medical records of all adult patients (age >18 years) discharged from Chang-Gung Memorial Hospital at Lin-Ko (CGMHLK) after treatment for tetanus between January 1996 and July 2005. Data regarding demographic characteristics, clinical manifestation, treatment, and outcome were collected. To assess the features for different age groups, patients were divided into those aged ≥65 years and those aged
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