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The purpose of this study was to report the distribution of mean ocular perfusion pressure (MOPP) and its associated factors in Chinese children.We enrolled 3048 grade 1 students and 2258 grade 7 students of the Anyang Childhood Eye Study in central China. Systolic and diastolic blood pressure (SBP and DBP) were recorded with a digital automatic sphygmomanometer. Intraocular pressure (IOP) was assessed by a non-contact tonometer. MOPP was calculated as 2/3 × (DBP + 1/3[SBP - DBP]) - IOP. Risk factors for myopia were obtained through a questionnaire survey.The MOPP was 33.83 ± 6.37 mm Hg (mean ± SD) in grade 1, which was lower than 36.99 ± 6.80 mm Hg in grade 7 (P0.001). Compared with myopic eyes, non-myopic eyes had higher MOPP in grade 7 (37.72 ± 6.72 mm Hg versus 36.58 ± 6.57 mm Hg, P0.001) and in grade 1 (33.88 ± 6.29 mm Hg versus 33.12 ± 7.03 mm Hg, P = 0.12). Multivariable analysis showed that higher MOPP was associated with less myopia (P0.001), higher body mass index (BMI; P0.001), thinner central corneal thickness (P0.001), less time on near work (P0.001), and more time on sleeping (P = 0.04).MOPP was higher in children of older age, with higher BMI, less time on near work, and more time on sleeping, and was higher in eyes with less myopia.We found that MOPP might be an indicator for the detection of myopia development.

// Dongling Teng 1, 2, * , Keyan Wu 1, 2, * , Yunyun Sun 1, 2, * , Min Zhang 1, 2 , Dan Wang 1, 2 , Jian Wu 1, 2 , Tao Yin 2 , Weijuan Gong 1, 2 , Yanbing Ding 1, 2 , Weiming Xiao 1, 2 , Guotao Lu 1, 2 and Weiqin Li 3 1 Department of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou 225000, Jiangsu, China 2 Laboratory of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou 225000, Jiangsu, China 3 Surgical Intensive Care Unit (SICU), Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, Jiangsu, China * These authors contributed equally to this work Correspondence to: Guotao Lu, email: Gtlu@yzu.edu.cn Weiming Xiao, email: wmxiao@yzu.edu.cn Keywords: acute pancreatitis; CA199; pancreatic cancer; retrospective study Received: October 13, 2017 Accepted: November 13, 2017 Published: January 04, 2018 ABSTRACT Background and study aims: Carbohydrate antigen 19-9 (CA199) has been identified as a tumor marker for pancreatic cancer but also increases in benign lesions of the digestive system. However, literature associated with the relationship between CA199 and acute pancreatitis (AP) is limited. This study aimed to focus on serum CA199 level measurements in AP patients and the associated clinical significance. Materials and methods: From January 2006 to December 2015, 1,609 consecutive patients with AP were admitted to our department and included in the study. The relationships among the etiology of AP, the disease severity, the incidence of pancreatic cancer during hospitalization and CA199 levels were analyzed. Results: Serum CA199 levels were measured for 693 of 1,609 AP patients. Of those patients, 186 (26.8%) had elevated CA199 levels (> 37 U/ml). Patients with high CA199 levels were older and had predominantly biliary causes in comparison with patients with normal CA199 levels. There were no definite specific correlations between CA199 levels and disease severity in AP. In addition, serum levels of CA199 positively correlated with serum alanine aminotransferase, aspartate transaminase, glutamyl transpeptidase, alkaline phosphatase and creatinine levels. After stratification, the incidence of pancreatic cancer increased proportionally to CA199 levels in AP patients. Conclusions: Serum CA199 levels was elevated in patients with AP, especially in patients with biliary pancreatitis. AP patients with significantly increased CA199 levels may have a higher risk for the presence of pancreatic cancer. We recommended routinely monitoring CA199 levels during hospitalization for AP patients.

Background There are few studies reporting the association between stature and ocular biometry as well as cycloplegic refraction in young adults. Our study determined the relationship between stature and ocular biometry as well as cycloplegic refraction in Chinese young adults. Methods This was a school-based study including university students in Anyang, Henan Province, China. Cycloplegic refraction and corneal curvature (CR) were measured using an autorefractor. Ocular biometric parameters, including axial length (AL), anterior chamber depth (ACD), and lens thickness (LT), were measured using a Lenstar LS900. Height and weight were acquired from an annual standardized physical examination, and body mass index (BMI) was calculated from these measurements. Results A total of 5657 (71.0%) subjects were available for analysis. After adjusting for age, gender, parental myopia, time outdoors, near work and weight, a 1 cm taller person could be expected to have more negative refraction as -0.023D, a 0.032 mm increase in AL, a 0.003 mm increase in ACD, a 0.008 mm increase in CR, and a 0.001 increase in axial length-corneal radius (AL/CR) ratio. With regard to weight, a 1 kg heavier person was more likely to have less negative refraction as 0.011 D, deeper ACD by 0.001mm and flatter cornea by 0.002mm. A similar pattern of significant associations was also found in BMI. Conclusions Compared to those of less height, young adults of greater height tended to have longer eyes, deeper anterior chambers, flatter corneas, higher AL/CR ratio, and more negative refraction after controlling for potential confounders. In contrast, heavier and higher BMI persons were more hyperopic. The differences in stature may partially explain the variation in refraction and ocular biometric parameters.

Interpenetrating polymer networks (IPNs) based on blocked polyurethane (BPU)/phenolic (PF) were prepared using simultaneous polymerization method. The IPN was prepared from BPU prepolymer with m-xylylenediamine as the chain extender and PF prepolymer using p-toluene sulfonic acid as a catalyst. From Fourier transform infrared spectra analysis, it was found that the major reactions in the BPU/PF IPN system are the polymerization of BPU/MXDA and the self-polymerization of PF. It was confirmed from scanning electron micrography that the BPU/PF IPN compatibility of the networks was improved, and the system was heterogeneous and more than one phase existed in the IPN. The tensile properties, flexural properties, impact, and hardness of the prepared IPN were studied. To obtain the best mechanical properties of IPN materials, the filler added in IPN materials has to be investigated. POLYM. ENG. SCI., 2011. © 2010 Society of Plastics Engineers

Background Pseudoachalasia is a rare disorder whose presentation strongly resembles idiopathic achalasia. Case presentation Here, we present a case of a 42-year-old female patient with esophageal leiomyoma who was initially diagnosed with achalasia. On endoscopical investigation, however, it became apparent that she had pseudoachalasia as consequence of a leiomyoma at the esophagogastric junction (EGJ). The condition was successfully treated through submucosal tunneling endoscopic resection. Conclusion This case suggests that submucosal tunneling endoscopic resection is a therapeutic u option for the treatment of pseudoachalasia caused by leiomyoma of EGJ.