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6 results on '"Zani, D. D."'

1. Paranasal sinus cysts in the horse: Complications related to their presence and surgical treatment in 37 cases

Author

Fenner, M. F., Verwilghen, D., Townsend, N., Simhofer, H., Schwarzer, J., Zani, D. D., Bienert-Zeit, A., Fenner, M. F., Verwilghen, D., Townsend, N., Simhofer, H., Schwarzer, J., Zani, D. D., and Bienert-Zeit, A.

Abstract

Background Paranasal sinus cysts (PSC) are a common cause of equine secondary sinusitis. The outcome and associated complications have not been frequently reported. Objectives To review the associated clinical signs, associated morbidities and outcomes of horses treated for PSC. Study design Retrospective multicentre case series. Methods Retrospective analysis of case records and telephone follow up survey. Results Subjects were 37 horses 1–24 years old that were presented with nasal discharge (n = 31), facial swelling (n = 25) and epiphora (n = 19). Radiography and computed tomography allowed identification of the cyst‐induced changes including concomitant tissue destruction (n = 31), leading among other things to local nerve damage causing headshaking (n = 6) and unilateral blindness (n = 1). Radiographic changes to adjacent dental apices were present in 10 horses. Horses over 10 years old showed more of the named associated problems. Post‐operative complications included surgical site infection (SSI) (n = 11), nasofrontal suture periostitis (n = 6) and sequestration (n = 1) following removal of the PSC via osteotomy. The long‐term response to treatment was available for 28 cases with 22 horses (78.6%) fully cured, 4 (14.3%) partially cured and 2 (7.1%) not responding to treatment. In 7 horses (18.9%) there was recurrence of the cyst post‐operatively. Main limitations Due to the study being a multicentre retrospective case series with collection of data over an extended period, there may be inconsistency in data recording and absence of reporting of some findings. Conclusions Overall, the diagnosis and treatment of sinus cysts is relatively straightforward and carries a good prognosis. In long‐standing cases complications secondary to the expansive growth of cysts will dramatically affect the prognosis for full recovery due to pressure‐induced changes to facial bones, cheek

Published
2019

2. Comparison of three novel biphasic scaffolds for one-stage treatment of osteochondral defects in a sheep model

Author

Gervaso, F., Mangiavini, L., Di Giancamillo, A., FEDERICA BOSCHETTI, Izzo, D., Zani, D. D., Di Giancamillo, M., Tessaro, I., Domenicucci, M., Scalera, F., Domeneghini, C., Crovace, A. M., Sannino, A., Peretti, G. M., Gervaso, Francesca, Mangiavini, L, Di Giancamillo, A, Boschetti, F, Izzo, D, Zani, D. D, Di Giancamillo, M, Tessaro, I, Domenicucci, M, Scalera, Francesca, Domeneghini, C, Crovace, A. M, Sannino, Alessandro, and Peretti, G. M.

Subjects
Sheep, Tissue Engineering, Tissue Scaffolds, Medicine (all), Osteocytes, Collagen Type I, Animal models, Scaffold, Disease Models, Animal, Cartilage, Chondrocytes, Durapatite, Animals, Femur, Bone Diseases, Osteochondral lesion, Tissue engineering
Abstract

In the last years, several tissue engineering techniques have been applied to develop different kinds of osteochondral substitutes to overcome the scarce reparative properties of this tissue. The aim of this study was to generate and compare three biphasic scaffolds in an osteochondral lesion in a large-animal model. A critical osteochondral defect was generated in the medial femoral condyle of 18 skeletally mature sheep. Three defects were left untreated, the remaining lesions were divided into three groups: 5 lesions were treated with a biphasic scaffold made of collagen type I and small cylinders of Magnesium Hydroxyapatite; 5 lesions were treated with a biphasic substituted formed by collagen type I and Wollastonite, 5 lesions were treated with a scaffold made of collagen type I and small cylinders of Wollastonite/Hydroxyapatite. Animals were sacrificed after 3 months and samples were analyzed by CT and MRI, macroscopic evaluation and histology. Our study demonstrated that one of these novel biphasic scaffolds possesses the potential for being applied for one-stage procedures for osteochondral defects.

Published
2016

3. A rare case of pituitary chromophobe carcinoma in a dog: clinical, tomographic and histopathological findings.

Author

De Zani, D., Ravasio, G., Di Giancamillo, M., Zani, D. D., Longo, M., Zagarella, P. G., Iocca, F., and Binanti, D.

Subjects
PITUITARY tumors, VETERINARY histopathology, MUTTS (Dogs), MAGNETIC resonance imaging of the brain, BRAIN diseases, GENETICS, DISEASES
Abstract

A 9 year old male mixed-breed dog was presented for progressive aggressiveness towards the owner. The neurological evaluation was consistent with a forebrain syndrome. Magnetic Resonance Imaging (MRI) of the brain revealed enlargement of the third ventricle and presence of a large spheroidal neoplasm in the sellar/parasellar region suggestive of a pituitary macroadenoma. On the owner request, the dog was euthanized. Histopathological examination revealed the presence of a pituitary chromophobe carcinoma. To the author's knowledge, pituitary carcinomas have been rarely described in dogs, especially the chromophobe subtype. [ABSTRACT FROM AUTHOR]

Published
2016
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4. Repeated occurrence of jejuno-jejunal intussusception in a calf

Author

Pravettoni, D., Morandi, N., Rondena, M., Riccaboni, P., Zani, D. D., Scandella, M., and Angelo Giovanni BELLOLI

Subjects
Laparotomy, Fatal Outcome, Recurrence, Anastomosis, Surgical, Animals, Cattle Diseases, Scientific, Cattle, Female, Jejunal Diseases, Intussusception
Abstract

This paper reports the clinical findings, diagnostic imaging, surgical management, and necropsy of an unusual case of jejuno-jejunal intussusception in a calf that was diagnosed with the use of ultrasonography, and treated surgically by resection and end-to-end anastomosis. The calf fatally relapsed 8 d after laparotomy. Necropsy and histology revealed enteritis and myenteric ganglionitis.

5. Comparison of three novel biphasic scaffolds for one-stage treatment of osteochondral defects in a sheep model.

Author

Gervaso F, Mangiavini L, Di Giancamillo A, Boschetti F, Izzo D, Zani DD, Di Giancamillo M, Tessaro I, Domenicucci M, Scalera F, Domeneghini C, Crovace AM, Sannino A, and Peretti GM

Subjects
Animals, Collagen Type I chemistry, Disease Models, Animal, Durapatite chemistry, Femur pathology, Bone Diseases pathology, Bone Diseases therapy, Chondrocytes pathology, Osteocytes pathology, Sheep, Tissue Engineering methods, Tissue Scaffolds chemistry
Abstract

In the last years, several tissue engineering techniques have been applied to develop different kinds of osteochondral substitutes to overcome the scarce reparative properties of this tissue. The aim of this study was to generate and compare three biphasic scaffolds in an osteochondral lesion in a large-animal model. A critical osteochondral defect was generated in the medial femoral condyle of 18 skeletally mature sheep. Three defects were left untreated, the remaining lesions were divided into three groups: 5 lesions were treated with a biphasic scaffold made of collagen type I and small cylinders of Magnesium Hydroxyapatite; 5 lesions were treated with a biphasic substituted formed by collagen type I and Wollastonite, 5 lesions were treated with a scaffold made of collagen type I and small cylinders of Wollastonite/Hydroxyapatite. Animals were sacrificed after 3 months and samples were analyzed by CT and MRI, macroscopic evaluation and histology. Our study demonstrated that one of these novel biphasic scaffolds possesses the potential for being applied for one-stage procedures for osteochondral defects.

Published
2016

6. A rare case of pituitary chromophobe carcinoma in a dog: clinical, tomographic and histopathological findings.

Author

Longo M, Binanti D, Zagarella PG, Iocca F, Zani D, Ravasio G, Giancamillo MD, and Zani DD

Abstract

A 9 year old male mixed-breed dog was presented for progressive aggressiveness towards the owner. The neurological evaluation was consistent with a forebrain syndrome. Magnetic Resonance Imaging (MRI) of the brain revealed enlargement of the third ventricle and presence of a large spheroidal neoplasm in the sellar/parasellar region suggestive of a pituitary macroadenoma. On the owner request, the dog was euthanized. Histopathological examination revealed the presence of a pituitary chromophobe carcinoma. To the author's knowledge, pituitary carcinomas have been rarely described in dogs, especially the chromophobe subtype.

Published
2016
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