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3. Population-based impact of COVID-19 on incidence, treatment, and survival of patients with pancreatic cancer

Author

Siesling, S., van Hoeve, J.C., Merkx, M.A.W., de Wit, N.J., Helsper, C.W., Dingemans, I., Nagtegaal, I.D., van der Schaaf, M., van Gils, C.H., van Weert, H.C.P.M., Verheij, M., Graus, Merlijn U.J.E., de Hingh, Ignace H.J.T., Besselink, Marc G., Bruno, Marco J., Wilmink, Johanna W., de Meijer, Vincent E., van Velthuysen, Marie-Louise F., Valkenburg-van Iersel, Liselot B.J., van der Geest, Lydia G.M., and de Vos-Geelen, Judith

Published
2023
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4. The CombiConsultation: Patient-centred pharmaceutical care by interprofessional collaboration

Author

Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Bouvy, Marcel, de Wit, N.J., Kwint, H, Heringa, Mette, Meijvis, Valérie Adriënne Marie, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Bouvy, Marcel, de Wit, N.J., Kwint, H, Heringa, Mette, and Meijvis, Valérie Adriënne Marie

Published
2024

7. Effectiveness of a guided online primary care intervention for fear of cancer recurrence: A randomised controlled trial

Author

Luigjes-Huizer, Y.L., Helsper, C.W., de Wit, N.J., van der Lee, M.L., Luigjes-Huizer, Y.L., Helsper, C.W., de Wit, N.J., and van der Lee, M.L.

Abstract

Objective Fear of Cancer Recurrence (FCR) is highly prevalent among cancer survivors and leads to decreased quality of life and increased healthcare costs. We assessed the effectiveness of a guided online primary care intervention for FCR, compared to waiting list. Methods In this RCT, participants were recruited online and randomised 1:1. All adults who finished successful curative cancer treatment between 3 months and 10 years ago, wanted support for FCR, and had sufficient Dutch skills were eligible. The intervention consisted of a 10‐week online programme and three to five video calling sessions with a trained mental health worker. After 6 months, the control group received the same intervention. The primary outcome was the difference between the groups in the change in FCR severity from baseline (T0) to 6 months (T2), measured online with the short form of the Fear of Cancer Recurrence Inventory. Results One hundred and seventy‐three participants were enroled and randomised to the intervention (n = 86) or control group (n = 87). FCR severity dropped 2.1 points more in the intervention group than in the control group (2.7 points (SD = 3.9) versus 0.6 points (SD = 3.6), t(154) = 3.4, p = 0.0007). General mental well‐being also improved significantly in the intervention group and remained stable in the control group. These improvements remained at 10 months follow up. Conclusions This easily accessible and relatively inexpensive intervention effectively reduces FCR and has potential to replace or precede existing more intensive psychological treatments, improving patients' access to care. Trial registration The trial was prospectively registered in the Netherlands Trial Register on 25‐02‐2019 with number NL7573

Published
2023

8. Population-based impact of COVID-19 on incidence, treatment, and survival of patients with pancreatic cancer

Author

Graus, Merlijn U.J.E., primary, de Hingh, Ignace H.J.T., additional, Besselink, Marc G., additional, Bruno, Marco J., additional, Wilmink, Johanna W., additional, de Meijer, Vincent E., additional, van Velthuysen, Marie-Louise F., additional, Valkenburg-van Iersel, Liselot B.J., additional, van der Geest, Lydia G.M., additional, de Vos-Geelen, Judith, additional, Siesling, S., additional, van Hoeve, J.C., additional, Merkx, M.A.W., additional, de Wit, N.J., additional, Helsper, C.W., additional, Dingemans, I., additional, Nagtegaal, I.D., additional, van der Schaaf, M., additional, van Gils, C.H., additional, van Weert, H.C.P.M., additional, and Verheij, M., additional

Published
2023
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11. Preventie:wat is het, en hoe benutten we het optimaal?

Author

Stronks, K., Stronks, K., Burdorf, A., Mölenberg, F.J.M., Kiefte, J.C., Kremers, S., Assendelft, W.J.J., Mierau, J.O., Peters, L.L., de Wit, N.J., van der Ven, G.L., Ballak, D.B., Stronks, K., Stronks, K., Burdorf, A., Mölenberg, F.J.M., Kiefte, J.C., Kremers, S., Assendelft, W.J.J., Mierau, J.O., Peters, L.L., de Wit, N.J., van der Ven, G.L., and Ballak, D.B.

Published
2022

12. Preventie:wat is het, en hoe benutten we het optimaal? (NFU paper)

Author

Stronks, K., Burdorf, A., Mölenberg, F.J.M., Kiefte, J.C., Kremers, S., Assendelft, W.J.J., Mierau, J.O., Peters, L.L., de Wit, N.J., van der Ven, G.L., Ballak, D.B., Stronks, K., Burdorf, A., Mölenberg, F.J.M., Kiefte, J.C., Kremers, S., Assendelft, W.J.J., Mierau, J.O., Peters, L.L., de Wit, N.J., van der Ven, G.L., and Ballak, D.B.

Published
2022

13. What is the prevalence of fear of cancer recurrence in cancer survivors and patients?: A systematic review and individual participant data meta-analysis

Author

Luigjes-Huizer, Y.L., Tauber, N.M., Humphris, G., Kasparian, N.A., Lam, W.W.T., Lebel, S., Simard, S., Smith, A.B., Zachariae, R., Afiyanti, Y., Bell, K.J.L., Custers, J.A.E., de Wit, N.J., Fischer, P.L., Galica, J., Garland, S.N., Helsper, C.W., Jeppesen, M.M., Liu, J., Mititelu, R., Monninkhof, E.M., Russell, L., Savard, J., Speckens, A.E.M., van Helmondt, S.J., Vatandoust, S., Zdenkowski, N., van der Lee, M.L., Luigjes-Huizer, Y.L., Tauber, N.M., Humphris, G., Kasparian, N.A., Lam, W.W.T., Lebel, S., Simard, S., Smith, A.B., Zachariae, R., Afiyanti, Y., Bell, K.J.L., Custers, J.A.E., de Wit, N.J., Fischer, P.L., Galica, J., Garland, S.N., Helsper, C.W., Jeppesen, M.M., Liu, J., Mititelu, R., Monninkhof, E.M., Russell, L., Savard, J., Speckens, A.E.M., van Helmondt, S.J., Vatandoust, S., Zdenkowski, N., and van der Lee, M.L.

Abstract

Objective Care for fear of cancer recurrence (FCR) is considered the most common unmet need among cancer survivors. Yet the prevalence of FCR and predisposing factors remain inconclusive. To support targeted care, we provide a comprehensive overview of the prevalence and severity of FCR among cancer survivors and patients, as measured using the short form of the validated Fear of Cancer Recurrence Inventory (FCRI-SF). We also report on associations between FCR and clinical and demographic characteristics. Methods This is a systematic review and individual participant data (IPD) meta-analysis on the prevalence of FCR. In the review, we included all studies that used the FCRI-SF with adult (≥18 years) cancer survivors and patients. Date of search: 7 February 2020. Risk of bias was assessed using the Joanna Briggs Institute critical appraisal tool. Results IPD were requested from 87 unique studies and provided for 46 studies comprising 11,226 participants from 13 countries. 9311 respondents were included for the main analyses. On the FCRI-SF (range 0–36), 58.8% of respondents scored ≥13, 45.1% scored ≥16 and 19.2% scored ≥22. FCR decreased with age and women reported more FCR than men. FCR was found across cancer types and continents and for all time periods since cancer diagnosis. Conclusions FCR affects a considerable number of cancer survivors and patients. It is therefore important that healthcare providers discuss this issue with their patients and provide treatment when needed. Further research is needed to investigate how best to prevent and treat FCR and to identify other factors associated with FCR. The protocol was prospectively registered (PROSPERO CRD42020142185).

Published
2022

17. Reducing unnecessary vitamin testing in general practice : Barriers and facilitators according to general practitioners and patients

Author

Hofstede, H., Van Der Burg, H.A.M., Mulder, B.C., Bohnen, A.M., Bindels, P.J.E., de Wit, N.J., de Schepper, E.I.T., van Vugt, S.F., Hofstede, H., Van Der Burg, H.A.M., Mulder, B.C., Bohnen, A.M., Bindels, P.J.E., de Wit, N.J., de Schepper, E.I.T., and van Vugt, S.F.

Abstract

Objective There has been an increase in testing of vitamins in patients in general practice, often based on irrational indications or for non-specific symptoms, causing increasing healthcare expenditures and medicalisation of patients. So far, there is little evidence of effective strategies to reduce this overtesting in general practice. Therefore, the aim of this qualitative study was to explore the barriers and facilitators for reducing the number of (unnecessary) vitamin D and B 12 laboratory tests ordered. Design and setting This qualitative study, based on a grounded theory design, used semistructured interviews among general practitioners (GPs) and patients from two primary care networks (147 GPs, 195 000 patients). These networks participated in the Reducing Vitamin Testing in Primary Care Practice (REVERT) study, a clustered randomized trial comparing two de-implementation strategies to reduce test ordering in primary care in the Netherlands. Participants Twenty-one GPs, with a maximum of 1 GP per practice who took part in the REVERT study, and 22 patients (who were invited by their GP during vitamin-related consultations) were recruited, from which 20 GPs and 19 patients agreed to participate in this study. Results The most important factor hampering vitamin-test reduction programmes is the mismatch between patients and medical professionals regarding the presumed appropriate indications for testing for vitamin D and B 12. In contrast, the most important facilitator for vitamin-test reduction may be updating GPs' knowledge about test indications and their awareness of their own testing behaviour. Conclusion To achieve a sustainable reduction in vitamin testing, guidelines with clear and uniform recommendations on evidence-based indications for vitamin testing, combined with regular (individual) feedback on test-ordering behaviour, are needed. Moreover, the general public needs access to clear and reliable information on vitamin testing. Further research is

Published
2019

19. Effectiveness and cost-effectiveness of proactive and multidisciplinary integrated care for older people with complex problems in general practice: An individual participant data meta-analysis

Author

Blom, J.W. (Jeanet), Hout, W.B. (Wilbert) van den, Elzen, W.P.J. (Wendy) den, Drewes, Y.M. (Yvonne M.), Bleijenberg, N. (Nienke), Fabbricotti, I.N. (Isabelle), Jansen, A.P.D. (Aaltje), Kempen, G.I.J.M. (Gertrudis), Koopmans, R. (R.), Looman, W.M. (Willemijn), Melis, R.J.F. (René), Metzelthin, S.F. (S. F.), Van Charante, E.P.M. (E.P. Moll), Muntinga, M.E. (Maaike E.), Numans, M.E. (Mattijs), Ruikes, F.G.H. (F. G.H.), Spoorenberg, S.L.W. (S. L.W.), Stijnen, T. (T.), Suijker, J.J. (J. J.), De Wit, N.J. (N. J.), Wynia, K. (K.), Wind, A.W. (Annet), Gussekloo, J. (Jacobijn), Blom, J.W. (Jeanet), Hout, W.B. (Wilbert) van den, Elzen, W.P.J. (Wendy) den, Drewes, Y.M. (Yvonne M.), Bleijenberg, N. (Nienke), Fabbricotti, I.N. (Isabelle), Jansen, A.P.D. (Aaltje), Kempen, G.I.J.M. (Gertrudis), Koopmans, R. (R.), Looman, W.M. (Willemijn), Melis, R.J.F. (René), Metzelthin, S.F. (S. F.), Van Charante, E.P.M. (E.P. Moll), Muntinga, M.E. (Maaike E.), Numans, M.E. (Mattijs), Ruikes, F.G.H. (F. G.H.), Spoorenberg, S.L.W. (S. L.W.), Stijnen, T. (T.), Suijker, J.J. (J. J.), De Wit, N.J. (N. J.), Wynia, K. (K.), Wind, A.W. (Annet), and Gussekloo, J. (Jacobijn)

Abstract

Purpose: to support older people with several healthcare needs in sustaining adequate functioning and independence, more proactive approaches are needed. This purpose of this study is to summarise the (cost-) effectiveness of proactive, multidisciplinary, integrated care programmes for older people in Dutch primary care. Methods design: individual patient data (IPD) meta-analysis of eight clinically controlled trials. Setting: primary care sector. Interventions: combination of (i) identification of older people with complex problems by means of screening, followed by (ii) a multidisciplinary integrated care programme for those identified. Main outcome: activities of daily living, i.e. a change on modified Katz-15 scale between baseline and 1-year follow-up. Secondary outcomes: quality of life (visual analogue scale 0-10), psychological (mental well-being scale Short Form Health Survey (SF)-36) and social well-being (single item, SF-36), quality-adjusted life years (Euroqol-5dimensions-3level (EQ-5D-3L)), healthcare utilisation and cost-effectiveness. Analysis: intention-to-treat analysis, two-stage IPD and subgroup analysis based on patient and intervention characteristics. Results: included were 8,678 participants: median age of 80.5 (interquartile range 75.3; 85.7) years; 5,496 (63.3%) women. On the modified Katz-15 scale, the pooled difference in change between the intervention and control group was -0.01 (95% confidence interval -0.10 to 0.08). No significant differences were found in the other patient outcomes or subgroup analyses. Compared to usual care, the probability of the intervention group to be cost-effective was less than 5%. Conclusion: compared to usual care at 1-year follow-up, strategies for identification of frail older people in primary care combined with a proactive integrated care intervention are probably not (cost-) effective.

Published
2018
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22. Multidisciplinaire richtlijn prikkelbaredarmsyndroom

Author

Woutersen-Koch, H., Smout, A.J.P.M., Flik, C.E., Hulshof, C.T.J., De Wit, N.J., van der Horst, H.E., General practice, and EMGO - Quality of care

Subjects
Econometric and Statistical Methods: General, Geneeskunde (GENK), Bescherming en bevordering van de menselijke gezondheid, Geneeskunde(GENK), Medical sciences, General [Econometric and Statistical Methods]
Published
2013

23. Effects of improved patient participation in primary care on health-related outcomes: a systematic review

Author

Sanders, A.R., Weeghel, I., Vogelaar, M., Verheul, W., Pieters, H.M., de Wit, N.J., Bensing, J.M., Stress and self-regulation, Leerstoel Bensing, and Afd Klinische psychologie

Subjects
Geneeskunde (GENK), Bescherming en bevordering van de menselijke gezondheid, Geneeskunde(GENK), Psychologie (PSYC), Medical sciences, General [Econometric and Statistical Methods]
Abstract

Background. In primary care, many consultations address symptom-based complaints. Recovery from these complaints seldom exceeds placebo effects. Patient participation, because of its supposed effects on trust and patient expectancies, is assumed to benefit patients’ recovery. While the idea is theoretically promising, it is still unclear what the effects of increased patient participation are on patient outcomes. Aim. To review the effects of controlled intervention studies aiming to improve patient participation in face-to-face primary care consultations on patient-oriented and/or disease-oriented outcomes. Methods. This study is a systematic review. A systematic search was undertaken for randomized controlled trials designed to measure the effects of interventions that aimed to improve adult patients’ participation in primary care visits. The CINAHL, Cochrane, EMBASE, PsycINFO and PubMed databases were searched. Results. Seven different trials fulfilled the inclusion criteria. Three of the studies were related to symptom-based complaints. Five studies measured patient-oriented outcomes, the primary outcome of interest for this review. All studies suffered from substantial bias. Studies varied widely in their aims, types of complaints/diseases, strength of the interventions and their outcomes. The effects on patient-oriented outcomes and disease-oriented outcomes were ambiguous. Conclusion. Little research has been performed on health outcomes of interventions aiming to increase patient participation in general practice visits among patients suffering from symptom-based complaints. The results still are non-conclusive. The quality of the trials has been weak, possibly due to the complexity of the concept. This weak quality may explain the lack of conclusive results. Proposals for future research designs are offered. Keywords. Patient participation, patient-oriented outcomes, primary health care, shared decision-making, review (publication type).

Published
2013

24. Relative risk of irritable bowel syndrome following acute gastroenteritis and associated risk factors

Author

Kowalcyk, B.K., Smeets, H.M., Succop, P.A., de Wit, N.J., Havelaar, A.H., Risk Assessment of Toxic and Immunomodulatory Agents, LS IRAS VPH MBR (microbiol.risico sch.), Dep IRAS, IRAS RATIA2, Risk Assessment of Toxic and Immunomodulatory Agents, LS IRAS VPH MBR (microbiol.risico sch.), Dep IRAS, and IRAS RATIA2

Subjects
Adult, Male, Risk, Diergeneeskunde, Pediatrics, medicine.medical_specialty, Time Factors, Adolescent, Epidemiology, Cohort Studies, Geneeskunde, Young Adult, Risk Factors, Humans, Medicine, Young adult, Prospective cohort study, Irritable bowel syndrome, Aged, irritable bowel syndrome, business.industry, Medical record, infectious disease epidemiology, Middle Aged, medicine.disease, Original Papers, Confidence interval, Gastroenteritis, Infectious Diseases, Concomitant, Relative risk, Female, business, gastroenteritis, Cohort study
Abstract

SUMMARYA prospective cohort study using electronic medical records was undertaken to estimate the relative risk (RR) of irritable bowel syndrome (IBS) following acute gastroenteritis (GE) in primary-care patients in The Netherlands and explore risk factors. Patients aged 18–70 years who consulted for GE symptoms from 1998 to 2009, met inclusion/exclusion criteria and had at least 1 year of follow-up data were included. Patients with non-GE consultations, matched by age, gender, consulting practice and time of visit, served as the reference group. At 1 year, 1·2% of GE patients (N = 2428) had been diagnosed with IBS compared to 0·3% of the reference group (N = 2354). GE patients had increased risk of IBS [RR 4·85, 95% confidence interval (CI) 2·02–11·63]. For GE patients, concomitant cramps and history of psycho-social consultations were significantly associated with increased risk. GE patients had increased risk of IBS up to 5 years post-exposure (RR 5·40, 95% CI 2·60–11·24), suggesting there may be other contributing factors.

Published
2013

25. Computerondersteunde zorg bij hart- en vaatziekten

Author

de Wit, N.J.

Subjects
Econometric and Statistical Methods: General, Bescherming en bevordering van de menselijke gezondheid, Geneeskunde(GENK), Medical sciences, General [Econometric and Statistical Methods]
Published
2012

26. Follow-up of mild alanine aminotransferase elevation identifies hidden hepatitis C in primary care

Author

Helsper, C.W., van Essen, G.A., Frijling, B.D., and de Wit, N.J.

Subjects
Male, Alanine Transaminase, Hepatitis C, Chronic, Middle Aged, digestive system diseases, Cross-Sectional Studies, Early Diagnosis, Hepatitis B, Chronic, Risk Factors, Prevalence, Humans, Female, Family Practice, Netherlands
Abstract

BACKGROUND: Hepatitis C (HCV) and hepatitis B (HBV) virus infection can lead to serious complications if left untreated, but often remain undetected in primary care. Mild alanine aminotransferase (ALT) elevations (30-100 IU/l) are commonly found and could be associated with viral hepatitis; unfortunately, these findings frequently remain without follow-up. AIM: To determine if and how mild ALT elevation can be used to identify hidden HCV and HBV infection in primary care. DESIGN AND SETTING: Primary care patients referred for liver enzyme testing were selected by a large primary care Diagnostic Centre (Saltro). METHOD: First, 750 anonymous samples were collected in three categories of ALT elevation (30-50 IU/l, 50-70 IU/l, and 70-100 IU/l) and tested for HCV and HBV. Second, the national prevalence of each ALT elevation was estimated by analysing all annual ALT tests performed at Saltro. RESULTS: HCV prevalence was 1.6% and 1.2% in patients with an ALT of 50-70 IU/l and 70-100 IU/l respectively. In patients with an ALT of 30-50 IU/l, HCV prevalence was normal (≤0.1%). HBV prevalence was normal (≤0.4%) in all groups. The estimated number of ALT tests performed nationally each year in primary care was 1.1 million. An ALT of 30-50 IU/l was found in 21.1%, an ALT of 50-70 IU/l in 5.6%, and 2.6% had an ALT of 70-100 IU/l. CONCLUSION: In primary care patients with an ALT level of 50-100 IU/l, HCV prevalence is tenfold the population prevalence, whereas HBV prevalence is not elevated. Therefore, diagnostic follow-up for HCV is indicated in these patients, even when other explanations for ALT elevation are present.

Published
2012

28. Disease burden of post-infectious irritable bowel syndrome in The Netherlands

Author

Haagsma, J.A., Siersema, P.D., de Wit, N.J., Havelaar, A.H., Risk Assessment of Toxic and Immunomodulatory Agents, Dep IRAS, Public Health, Gastroenterology & Hepatology, Risk Assessment of Toxic and Immunomodulatory Agents, and Dep IRAS

Subjects
medicine.medical_specialty, Epidemiology, Campylobacteriosis, Disease, Medical sciences, Irritable Bowel Syndrome, Risk Factors, Internal medicine, medicine, Humans, Bescherming en bevordering van de menselijke gezondheid, Geneeskunde(GENK), Irritable bowel syndrome, Disease burden, Netherlands, Econometric and Statistical Methods: General, business.industry, Incidence, Incidence (epidemiology), Bacterial Infections, medicine.disease, General [Econometric and Statistical Methods], Gastroenteritis, Surgery, Quality-adjusted life year, Infectious Diseases, Attributable risk, Quality of Life, Quality-Adjusted Life Years, business
Abstract

SUMMARYPost-infectious irritable bowel syndrome (PI-IBS) has been established as a sequel of infectious intestinal disease (IID). The aim of this study was to estimate the burden of PI-IBS caused by the pathogens Campylobacter, Salmonella and Shigella, and to compare this with other outcomes associated with these pathogens. The attributable risk of PI-IBS due to bacterial pathogens was calculated and linked to national data on gastroenteritis incidence and measures for severity and duration of illness in order to estimate the burden of PI-IBS. One year post-infection, IBS developed in 9% of patients with bacterial IID. The burden of PI-IBS adds over 2300 disability adjusted life years to the total annual disease burden for the selected pathogens. PI-IBS is a frequent sequel of IID, resulting in a considerable disease burden compared to other outcomes. If this relationship is not considered, this will result in an underestimation of the disease burden of IID.

Published
2010

31. Zuurremmers: hoog inzetten, of juist laag? Het DIAMOND-onderzoek naar effectiviteit en kosten van de step-up en de step-downbenadering bij maagklachten in de eerste lijn

Author

van Marrewijk, C.J., Mujakovic, S., Fransen, G.A., Numans, M.E., de Wit, N.J., Muris, J.W.M., van Oijen, M.G.H., Jansen, J.B., Grobbee, D.E., Knottnerus, J.A., and Laheij, R.J.F.

Subjects
Genomic disorders and inherited multi-system disorders [IGMD 3], Molecular epidemiology [NCEBP 1], Molecular gastro-enterology and hepatology [IGMD 2]
Abstract

Contains fulltext : 79806.pdf (Publisher’s version ) (Closed access)

Published
2009

34. Relative risk of irritable bowel syndrome following acute gastroenteritis and associated risk factors

Author

Risk Assessment of Toxic and Immunomodulatory Agents, LS IRAS VPH MBR (microbiol.risico sch.), Dep IRAS, IRAS RATIA2, Kowalcyk, B.K., Smeets, H.M., Succop, P.A., de Wit, N.J., Havelaar, A.H., Risk Assessment of Toxic and Immunomodulatory Agents, LS IRAS VPH MBR (microbiol.risico sch.), Dep IRAS, IRAS RATIA2, Kowalcyk, B.K., Smeets, H.M., Succop, P.A., de Wit, N.J., and Havelaar, A.H.

Published
2014

35. Systematic review: probiotics in the management of lower gastrointestinal symptoms in clinical practice – an evidence-based international guide

Author

Hungin, A.P., Mulligan, C., Pot, B., Whorwell, P., Agréus, L., Fracasso, P., Lionis, C., mendive, J, Philipart de Foy, J.M., Rubin, G., Winchester, C., de Wit, N.J., Hungin, A.P., Mulligan, C., Pot, B., Whorwell, P., Agréus, L., Fracasso, P., Lionis, C., mendive, J, Philipart de Foy, J.M., Rubin, G., Winchester, C., and de Wit, N.J.

Published
2013

36. Self-management : one size does not fit all

Author

Trappenburg, J.C.A., Jonkman, N.H., Jaarsma, T., van Os-Medendorp, H., Kort, H., de Wit, N.J., Hoes, A.W., Schuurmans, M.J., Trappenburg, J.C.A., Jonkman, N.H., Jaarsma, T., van Os-Medendorp, H., Kort, H., de Wit, N.J., Hoes, A.W., and Schuurmans, M.J.

Published
2013

40. Samenvatting van de NHG-Standaard Maagklachten

Author

de Jongh, E., Numans, M.E., de Wit, N.J., Heemstra-Borst, C.G., Geijer, R., Burgers, J.S., de Jongh, E., Numans, M.E., de Wit, N.J., Heemstra-Borst, C.G., Geijer, R., and Burgers, J.S.

Published
2013

46. Systematic review: probiotics in the management of lower gastrointestinal symptoms in clinical practice – an evidence-based international guide

Author

JC Overig onderzoek, Cancer, General Practice & Nursing Science, Hungin, A.P., Mulligan, C., Pot, B., Whorwell, P., Agréus, L., Fracasso, P., Lionis, C., mendive, J, Philipart de Foy, J.M., Rubin, G., Winchester, C., de Wit, N.J., JC Overig onderzoek, Cancer, General Practice & Nursing Science, Hungin, A.P., Mulligan, C., Pot, B., Whorwell, P., Agréus, L., Fracasso, P., Lionis, C., mendive, J, Philipart de Foy, J.M., Rubin, G., Winchester, C., and de Wit, N.J.

Published
2013

47. Analytical performance, agreement and user-friendliness of five C-reactive protein point-of-care tests

Author

Brain, Circulatory Health, Infection & Immunity, JC onderzoeksprogramma Infectieziekten, JC Overig onderzoek, Cancer, General Practice & Nursing Science, Epidemiology & Health Economics, Minnaard, M.C., van de Pol, A.C., Broekhuizen, B.D.L., Verheij, Th.J.M., Hopstaken, R.M., van Delft, S., Kooijman-Buiting, A.M., de Groot, J.A.H., de Wit, N.J., Brain, Circulatory Health, Infection & Immunity, JC onderzoeksprogramma Infectieziekten, JC Overig onderzoek, Cancer, General Practice & Nursing Science, Epidemiology & Health Economics, Minnaard, M.C., van de Pol, A.C., Broekhuizen, B.D.L., Verheij, Th.J.M., Hopstaken, R.M., van Delft, S., Kooijman-Buiting, A.M., de Groot, J.A.H., and de Wit, N.J.

Published
2013

48. Exploring the expectations, needs and experiences of general practitioners and nurses towards a proactive and structured care programme for frail older patients: a mixed-methods study

Author

Brain, JC Overig onderzoek, Other research (not in main researchprogram), Cancer, General Practice & Nursing Science, Revalidatie/Sportgeneeskunde Medisch, Bleijenberg, N., ten Dam, V.H., Steunenberg, B., Drubbel, I., Numans, M.E., de Wit, N.J., Schuurmans, M.J., Brain, JC Overig onderzoek, Other research (not in main researchprogram), Cancer, General Practice & Nursing Science, Revalidatie/Sportgeneeskunde Medisch, Bleijenberg, N., ten Dam, V.H., Steunenberg, B., Drubbel, I., Numans, M.E., de Wit, N.J., and Schuurmans, M.J.

Published
2013

49. Multidisciplinaire richtlijn Polyfarmacie bij ouderen

Author

JC Overig onderzoek, Cancer, General Practice & Nursing Science, MS Geriatrie, Verduijn, M., Leendertse, A., Moeselaar, A., de Wit, N.J., van Marum, R.J., JC Overig onderzoek, Cancer, General Practice & Nursing Science, MS Geriatrie, Verduijn, M., Leendertse, A., Moeselaar, A., de Wit, N.J., and van Marum, R.J.

Published
2013

50. Referrals for recurrent respiratory tract infections including otitis media in young children.

Author

Child Health, Infection & Immunity, JC Overig onderzoek, JC onderzoeksprogramma Methodologie, Other research (not in main researchprogram), Cancer, General Practice & Nursing Science, Longziekten, Zorgeenheid KNO Medisch, Epidemiology & Health Economics, Cardiometabolic Health, JC onderzoeksprogramma Infectieziekten, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Data Science & Biostatistiek, van de Pol, A.C., van der Gugten, A.C., van der Ent, C.K., Schilder, A.G.M., Benthem, E.M., Smit, H.A., Stellato, R.K., de Wit, N.J., Damoiseaux, R.A.M.J., Child Health, Infection & Immunity, JC Overig onderzoek, JC onderzoeksprogramma Methodologie, Other research (not in main researchprogram), Cancer, General Practice & Nursing Science, Longziekten, Zorgeenheid KNO Medisch, Epidemiology & Health Economics, Cardiometabolic Health, JC onderzoeksprogramma Infectieziekten, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Data Science & Biostatistiek, van de Pol, A.C., van der Gugten, A.C., van der Ent, C.K., Schilder, A.G.M., Benthem, E.M., Smit, H.A., Stellato, R.K., de Wit, N.J., and Damoiseaux, R.A.M.J.

Published
2013

Catalog

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