1. Acute encephalopathy with biphasic seizures and late reduced diffusion in a Spanish girl.
- Author
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García-Boyano, Miguel, Caballero-Caballero, José Manuel, Alguacil-Guillén, Marina, and Baquero-Artigao, Fernando
- Subjects
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SEIZURES (Medicine) , *DIFFUSION , *PROTON magnetic resonance spectroscopy , *CALCITONIN , *C-reactive protein - Abstract
We report a case of a 22-month-old Spanish girl who presented acute encephalopathy with biphasic seizures and late reduced diffusion (AESD). Serum procalcitonin (PCT) reached a maximum of 50.5 ng/mL on the first day whereas C-reactive protein (CRP) peaked at 1.21 mg/dL on the second. At the time of discharge, right spastic hemiparesis persisted. MR spectroscopy on day 23 revealed a decrease in N-acetylaspartate and an increase in choline. To our knowledge, we report the first case of AESD in Europe. These findings support the role of PCT and PCT/CRP ratio in the early diagnosis of AESD and correlation of MR spectroscopy findings with neurological outcome. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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