1. Short-term exposure to ambient air pollution and hospital admissions for angina among older adults in South China.
- Author
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Xu, Luxi, Xu, Ruijun, Ye, Yunshao, Wang, Rui, Wei, Jing, Shi, Chunxiang, Lin, Qiaoxuan, Lv, Ziquan, Huang, Suli, Tian, Qi, and Liu, Yuewei
- Subjects
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AIR pollution , *OLDER people , *HOSPITAL admission & discharge , *ANGINA pectoris , *AIR pollutants , *CARBOXYHEMOGLOBIN - Abstract
Ambient air pollution has been linked to an increased risk of various acute cardiovascular outcomes; however, its effects on hospital admissions for angina are yet to be evaluated. We conducted a time-stratified case-crossover study with conditional logistic regression models among 46,687 adults 60 years or older who were admitted to hospital for angina in Guangzhou, China during 2016–2019 to investigate the association of exposure to ambient particulate matter with an aerodynamic diameter ≤2.5 μm (PM 2.5), particulate matter with an aerodynamic diameter ≤10 μm (PM 10), sulfur dioxide (SO 2), nitrogen dioxide (NO 2), carbon monoxide (CO), and ozone (O 3) with hospital admissions for angina. Daily residential air pollutant exposures were extracted from a grid dataset. Each 10 μg/m3 increase of lag 0-day exposure to PM 10 , SO 2 , NO 2 , CO, and O 3 was significantly associated with a 0.80% (95% confidential interval: 0.32%, 1.28%), 4.04% (0.34%, 7.89%), 2.47% (1.81%, 3.12%), 0.13% (0.07%, 0.19%), and −0.38% (−0.74%, −0.01%) increase in odds of admission, respectively. The association for NO 2 exposure remained stable, while the associations for PM 10 , SO 2 , CO, and O 3 became insignificant with adjustment for other air pollutants. The association for NO 2 exposure was stronger in cool season. We estimated that up to 9.12% of angina admissions were attributable to NO 2 exposure. Our findings suggest that ambient NO 2 may trigger hospital admissions for angina in Chinese older adults, which highlights the importance to prevent angina by reducing individual NO 2 exposures. • Short-term exposure to ambient NO 2 was associated with an increased odds of angina admissions in older adults. • The association for NO 2 was stronger in cool season. • Reducing traffic-related air pollution may be helpful in preventing angina admissions. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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