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Introduction: the detection of gastric preneoplastic lesions (atrophic gastritis, intestinal metaplasia, dysplasia) is important regarding the patient's risk evaluation for gastric cancer. The purpose of this study consists in the pit pattern evaluation, specific to the 3 premalignant lesions by magnifying endoscopy and chromeondoscopy. Material and methods: The study has started in January 2010 and it is still in progress. The patients have been examined by conventional endoscopy, respectively selected for magnifying endoscopy and chromoendoscopy. Partial results: I have obtained pit patterns specific to gastric mucosa in precancerous lesions. Partial conclusions: 1. Several pit patterns can be identified in the same patient. 2. The stomach can be mapped more exactly, this way being identified the area of modified mucosa; thus target biopsies can be done raising the chances for an accurate diagnosis. 3. It is a resource and time-consuming method. [ABSTRACT FROM AUTHOR]

Background: Often early gastric cancer (EGC) is asymptomatic, that is why most of the patients come for medical investigation already ill with advanced gastric cancer. The detection of premalignant gastric lesions and their control, help the exposure of gastric cancer in its initial stage and implicitly to a prompter access to the appropriate treatment for the patients. This study quantifies the utility of narrow band imaging-endoscopy (NBI) for the detection of premalignant lesions and early gastric cancer. Material and methods: This prospective study included 63 patients. They underwent an examination with white light endoscopy (WLE) and Sidney system of biopsy followed by magnifying NBI with targeted biopsies. We monitored the presence of EGC, dysplasia (Dis), intestinal metaplasia (IM). Results: IM was diagnosed in 60 patients, and 128 areas. Dis was detected in 11 patients and 13 areas and 2 patients had EGC. The premalignant gastric lesions were detected by both investigation methods. We followed sensibility, specificity, positive, negative predictive values. For NBI we obtained 81%, 75%, and for WLE 52%, 68%. The EGC was diagnosed only with NBI. Conclusions: NBI endoscopy is better than WLE for detected IM, Dis and EGC. This method can be used for screening EGC. [ABSTRACT FROM AUTHOR]