1. Design and Synthesis of a Fluorescent Probe Based on Copper Complex for Selective Detection of Hydrogen Sulfide.
- Author
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Mao, Guanglan, Liu, Chenxi, Yang, Nan, Yang, Linlin, and He, Guangjie
- Subjects
HYDROGEN sulfide ,COPPER compounds ,FLUORESCENT probes ,FLUORESCENCE spectroscopy ,DENSITY functional theory ,ABSORPTION spectra ,MOLECULAR spectra - Abstract
A novel fluorescence probe NA-LCX was rationally designed and synthesized for the sequential recognition of Cu
2+ and H2 S by the combination of hydroxyl-naphthalene and diformylphenol groups. The response properties of NA-LCX for Cu2+ ions and H2 S with "on-off-on" manner were investigated by fluorescence emission spectra. A highly selective and sensitive response of complex NA-LCX-Cu2+ for H2 S over other competing amino acids was observed with a limit of detection at 2.79 μM. The stoichiometry of NA-LCX toward Cu2+ ions was determined to be 1 : 1 by the UV-Vis absorption spectrum, and the coordination configuration was calculated by density functional theory (DFT) calculations. Moreover, probe NA-LCX was applied successfully for the recognition of Cu2+ ions and H2 S in living cells. [ABSTRACT FROM AUTHOR]- Published
- 2021
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