1. Point-of-Care Periodontitis Testing: Biomarkers, Current Technologies, and Perspectives.
- Author
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He W, You M, Wan W, Xu F, Li F, and Li A
- Subjects
- Humans, Time Factors, Biomarkers analysis, Diagnostic Tests, Routine methods, Periodontitis diagnosis, Point-of-Care Systems
- Abstract
Periodontitis has become one of the most universal chronic inflammatory diseases worldwide. Subclinical symptom progression, ultimately leading to permanent damage, calls for early diagnosis and long-term monitoring. However, traditional clinical diagnostic methods are complex and expensive, and cannot meet these requirements. Recently, with more biomarkers and the development of new technologies, various point-of-care testing (POCT) platforms have been developed for periodontitis diagnosis and monitoring. These are easy to perform, rapid, low-cost, and are perfectly suited for high-frequency diagnosis of periodontitis at the point-of-care (POC). We summarize existing biomarkers of different periodontitis stages and recent developed POCT platforms (including lab-on-a-chip, paper-based platforms, and chairside tests), discuss their existing challenges and future potential, and provide some inspiration and guidelines for future POC periodontitis testing., (Copyright © 2018 Elsevier Ltd. All rights reserved.)
- Published
- 2018
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