1. Detection of highly pathogenic avian influenza A(H5N6) viruses in waterfowl in Bangladesh.
- Author
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Yang, Genyan, Chowdury, Sukanta, Hodges, Erin, Rahman, Mohammed Ziaur, Jang, Yunho, Hossain, Mohammad Enayet, Jones, Joyce, Stark, Thomas J., Di, Han, Cook, Peter W., Ghosh, Sumon, Azziz-Baumgartner, Eduardo, Barnes, John R., Wentworth, David E., Kennedy, Erin, and Davis, C. Todd
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AVIAN influenza , *AVIAN influenza A virus , *WATERFOWL , *VIRUSES , *INFLUENZA viruses , *SPECIFIC gravity - Abstract
Bangladesh has reported repeated outbreaks of highly pathogenic avian influenza (HPAI) A(H5) viruses in poultry since 2007. Because of the large number of live poultry markets (LPM) relative to the population density of poultry throughout the country, these markets can serve as sentinel sites for HPAI A(H5) detection. Through active LPM surveillance during June 2016–June 2017, HPAI A(H5N6) viruses along with 14 other subtypes of influenza A viruses were detected. The HPAI A(H5N6) viruses belonged to clade 2.3.4.4 and were likely introduced into Bangladesh around March 2016. Human infections with influenza clade 2.3.4.4 viruses in Bangladesh have not been identified, but the viruses had several molecular markers associated with potential human infection. Vigilant surveillance at the animal-human interface is essential to identify emerging avian influenza viruses with the potential to threaten public and animal health. • HPAI A(H5) viruses have been circulating in Bangladesh since 2007, resulting in hundreds of poultry outbreaks and sporadic human infections. • Market based surveillance was established in Bangladesh in 2007 to identify HPAI viruses that pose a potential threat to human and animal health. • This study describes the influenza A subtypes identified from June 2016 to June 2017 and reports detection of clade 2.3.4.4 H5N6 viruses in Bangladesh. • We also assessed the evolution and antigenic properties of these viruses and potential modes and timing of emergence. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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