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γ-Oryzanol, a mixture of ferulic acid esters of triterpene alcohols and sterols, is a nutritionally important group of rice secondary metabolites. A library of 27 γ-oryzanol was assembled from existing data and used to assist identification and quantification of γ-oryzanol isolated from 16 Korean rice varieties (11 white and 5 pigmented). γ-Oryzanol was analyzed with liquid chromatography with diode array detection and electrospray ionization mass spectrometry. Nineteen different γ-oryzanol were observed and identified as stigmasterol, campesterol and sitosterol or common and hydroxylated triterpene alcohols. In the 16 varieties, the total γ-oryzanol content averaged 43.8 mg/100 g (range, 26.7-61.6 mg/100 g), which Josaengheugchal exhibited the highest level (61.6 mg/100 g). The Korean rice varieties were classified based on qualitative and quantitative γ-oryzanol data by multivariate statistical analysis. Clusters of specialty rice varieties exhibited higher γ-oryzanol levels than those of common rice varieties. [ABSTRACT FROM AUTHOR]

Aims The Korean Acute Heart Failure registry ( KorAHF) aims to evaluate the clinical characteristics, management, hospital course, and long-term outcomes of patients hospitalized for acute heart failure syndrome ( AHFS) in Korea. Methods and results This is a prospective observational multicentre cohort study funded by the Korea National Institute of Health. Patients hospitalized for AHFS in 10 tertiary university hospitals across the country have been consecutively enrolled since March 2011. The study is expected to complete the scheduled enrolment of 5000 patients some time in 2014, and follow-up is planned through 2016. As of April 2012, the interim analysis of 2066 consecutive subjects was performed to understand the baseline characteristics of the population. The mean age was 69 ± 14 years; 55% were male; and 50% were de novo heart failure. The mean left ventricular ejection fraction ( LVEF) was 40 ± 18%. Ischaemia was both the leading cause (38%) and the most frequent aggravating factor (26%) of AHFS. ACE inhibitors/ ARBs and beta-blockers were prescribed at discharge in 65% and 51% of the patients, respectively. In-hospital mortality was 5.2%, and 0.9% of patients received urgent heart transplantation. Low blood pressure and azotaemia were the most important predictors of in-hospital mortality. The post-discharge 30-day and 180-day all-cause mortality were 1.2% and 9.2%, respectively. Conclusions Our analysis reveals that the prognosis of AHFS in Korea is poor and that there are specific features, including lower blood pressures at admission and lower rates of heart failure related to hypertension, compared with other registries. Adherence to current guidelines should be improved. [ABSTRACT FROM AUTHOR]

Purpose: This study has attempted to comparatively analyze the parenting stress that parents of a child with leukemia and their information needs at the end of treatment after complete remission (CR) of leukemia. Methods: For data collection, a structured questionnaire survey on parenting stress and information needs was conducted using parents of children with leukemia visiting the Blood & Marrow Transplantation Center at C University Hospital in Seoul from August to December 2011. A total of 100 parents were examined. Results: The parents of children under treatment after CR had greater parenting stress than parents of children whose treatment was finished. The parents of children whose treatment was finished had greater information needs than the parents of children whose treatment was ongoing. The differences had no statistical significance. In both groups, information needs about patients' growth development and school adjustment was high. Conclusion: This study confirms that it is necessary to add information about daily life management, child's growth development, sociopsychological adaptation, school adjustment, and support of family, to the current symptom care-centered education program. [ABSTRACT FROM AUTHOR]