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Highlights: [•] The full-length cDNA of four nr5as were isolated and characterized from G. rarus. [•] 17 Steroidogenesis-related genes expression was studied after BPA exposure. [•] Gene expression was dependent on BPA concentration and exposure duration. [•] BPA actions might involve Esr/Fshr pathway and transcription factors. [ABSTRACT FROM AUTHOR]

Previously, we have reported that the dysregulation of ketogenesis plays an important role in the carcinogenesis of clear cell renal cell carcinoma (ccRCC). Here, we demonstrate decreased expression of the HMGCS2 gene in ccRCC, a critical enzyme for the synthesis of the ketone body β-hydroxybutyrate (β-OHB). We found that the reduced transcription of the HMGCS2 gene in ccRCC cells was significantly correlated to a higher relative methylation rate in its promotor region. The higher methylation rate in the region of the transcription start site and 1st exon of the HMGCS2 gene was, in turn, correlated with a worse clinical outcome for patients. The transcription of HMGCS2 was possible to restore by treatment with 5-aza-2′-deoxycytidine and with the histone deacetylase inhibitor β-OHB. Therefore, the low levels of the HMGCS2 enzyme in ccRCC may be the consequence of hypermethylation of the HMGCS2 promotor. The ensuing reduction in the ketone body levels further suppresses the transcription of HMGCS2 via a feedback loop. Ectopic expression of HMGCS2 attenuates the migration and invasion of ccRCC but does not affect the proliferative capacity of ccRCC cells in vitro. In addition, we showed that ectopic expression of HMGCS2 boosts the intracellular levels of β-OHB and that exogenously applied β-OHB suppresses the motility and invasion of ccRCC. Our study reveals crosstalk between genes that regulate metabolism and their metabolites, thus providing a better understanding of the epigenetic mechanism involved in ccRCC carcinogenesis and suggesting opportunities for metabolic therapy of tumors. Initially, we suggest that the mRNA level of HMGCS2 could serve as a potentially valuable diagnostic (AUC = 0.918, p < 0.001) and prognostic biomarker. [ABSTRACT FROM AUTHOR]

A novel series of fluorinated 2-phenylindole derivatives were synthesized and evaluated as β-amyloid imaging probes for PET. The in vitro inhibition assay demonstrated that their binding affinities for Aβ1–42 aggregates ranged from 28.4 to 1097.8nM. One ligand was labeled with 18F ([18F]1a) for its high affinity (K i =28.4nM), which was also confirmed by in vitro autoradiography experiments on brain sections of transgenic mouse (C57BL6, APPswe/PSEN1, 11months old, male). In vivo biodistribution experiments in normal mice showed that this radiotracer displayed high initial uptake (5.82±0.51% ID/g at 2min) into and moderate washout (2.77±0.31% ID/g at 60min) from the brain. [18F]1a could be developed as a promising new PET imaging probe for Aβ plaques although necessary modifications are still needed. [ABSTRACT FROM AUTHOR]

Abstract: Zona pellucida (ZP) proteins are glycoproteins synthesized in liver, ovary or in both tissues in fish. In the present study, we aimed to determine the responsiveness of ZP2 and ZP3 to 17α-ethinylestradiol (EE2) in adult rare minnow Gobiocypris rarus. The full length of ZP3 cDNA was firstly characterized and its tissue distribution revealed that ZP3 mRNA was predominantly expressed in ovary of G. rarus. The gene expression profiles of ZP2, ZP3 and vitellogenin (VTG) were analyzed in gonad and liver of adult G. rarus exposed to EE2 at 1, 5, 25, and 125ng/L for 3 and 6days. The results show that ZP2 is more sensitive than ZP3 in gonads of both genders, and VTG in liver is extremely sensitive to EE2 in male fish. However, at lower concentrations (1 and 5ng/L), the ZP2 in testes shows higher responsiveness to EE2 compared with VTG in rare minnow. The 5′ flanking regions of ZP2 and ZP3 were isolated and the comparison of transcription factors in the regions of ZP2 and ZP3 suggested that the disparity for the responsiveness of ZP2 and ZP3 to EE2 could partly be a result of differential cis-elements such as oocyte-specific protein (Osp1) binding sites or/and sex-determining region Y (SRY) binding site. [Copyright &y& Elsevier]

Abstract: In order to evaluate the energy utilization efficiency of gasoline engine and predict the recovery potential for waste heat energy, energy distribution and waste heat energy characteristics of a naturally aspirated gasoline engine have been studied by combining the methods of energy and exergy analysis. During the research processes, engine energy balance tests were conducted under mapping characteristics, and the parameters required for calculating the energy balance and exergy balance were measured. On this basis, waste heat recovery potential and gasoline engine total exergy efficiency were studied by using the method of exergy analysis. Research results show: at low-speed and low-load, waste heat energy mainly focuses on cooling water; at high-speed and high-load, exhaust gas energy is larger than cooling water energy not only in quantity, but also in exergy percentage and exergy efficiency; the highest exhaust gas exergy efficiency appears in high-speed and high-load area, while the highest cooling water exergy efficiency appears in low-speed and low-load area; theoretically, total fuel efficiency of this gasoline engine can be nearly improved by a time through waste heat recovery, and the maximum total fuel efficiency can reach 60%. [Copyright &y& Elsevier]

Rhenium and technetium-99m cyclopentadienyl tricarbonylcomplexesmimicking the chalcone structure were prepared. These complexes wereproved to have affinity to β-amyloid (Aβ) in fluorescentstaining on brain sections of Alzheimer’s Disease (AD) patientand binding assay using Aβ1–42aggregates,with Kivalues ranging from 899 to 108nM as the extension of conjugated π system. In vitro autoradiograpyon sections of transgenic mouse brain confirmed the affinity of [99mTc]5(Ki= 108nM). In biodistribution, all compounds showed good initial uptakesinto the brain and fast blood clearance, while the decreasing of initialbrain uptakes correspond to increasing of conjugation length, from4.10 ± 0.38% ID/g ([99mTc]3) to 1.11± 0.34% ID/g ([99mTc]5). These smalltechnetium-99m complexes (<500 Da) designed by an integrated approachprovide encouraging evidence that development of a promising 99mTc-labeled agent for imaging Aβ plaques in the brainmay be feasible. [ABSTRACT FROM AUTHOR]

A series of fluoro-pegylated (FPEG) 2-pyridinylbenzoxazoleand2-pyridinylbenzothiazole derivatives were synthesized and evaluatedas novel β-amyloid (Aβ) imaging probes for PET. They displayedbinding affinities for Aβ1–42aggregates thatvaried from 2.7 to 101.6 nM. Seven ligands with high affinity wereselected for 18F labeling. In vitro autoradiography resultsconfirmed the high affinity of these radiotracers. In vivo biodistributionexperiments in normal mice indicated that the radiotracers with ashort FPEG chain (n= 1) displayed high initial uptakeinto and rapid washout from the brain. One of the 2-pyridinylbenzoxazolederivatives, [18F]-5-(5-(2-fluoroethoxy)benzo[d]oxazol-2-yl)-N-methylpyridin-2-amine ([18F]32) (Ki= 8.0 ± 3.2nM) displayed a brain2min/brain60minratio of4.66, which is highly desirable for Aβ imaging agents. Targetspecific binding of [18F]32to Aβ plaqueswas validated by ex vivo autoradiographic experiment with transgenicmodel mouse. Overall, [18F]32is a promisingAβ imaging agent for PET and merits further evaluation in humansubjects. [ABSTRACT FROM AUTHOR]

Abstract: In continuation of our study on the 2-phenylquinoxaline scaffold as potential β-amyloid imaging probes, two [18F]fluoro-pegylated 2-phenylquinoxaline derivatives, 2-(4-(2-[18F]fluoroethoxy)phenyl)-N-methylquinoxalin-6-amine ([18F]4a) and 2-(4-(2-(2-(2-[18F]fluoroethoxy)ethoxy)ethoxy)phenyl)-N-methylquinoxalin-6-amine ([18F]4b) were prepared. Both of them displayed high binding affinity to Aβ 1-42 aggregates (K i = 10.0 ± 1.4 nM for 4a, K i = 5.3 ± 3.2 nM for 4b). The specific and high binding of [18F]4a and [18F]4b to Aβ plaques was confirmed by in vitro autoradiography on brain sections of AD human and transgenic mice. In biodistribution in normal mice, [18F]4a displayed high initial brain uptake (8.17% ID/g at 2 min) and rapid washout from the brain. These preliminary results suggest [18F]4a may be a potential PET imaging agent for Aβ plaques in the living human brain. [Copyright &y& Elsevier]

Abstract: Two uncharged 99mTc-labeled phenylbenzoxazole derivatives were biologically evaluated as potential imaging probes for β-amyloid plaques. The 99mTc and corresponding rhenium complexes were synthesized by coupling monoamine–monoamide dithiol (MAMA) and bis(aminoethanethiol) (BAT) chelating ligand via a pentyloxy spacer to phenylbenzoxazole. The fluorescent rhenium complexes 6 and 9 selectively stainined the β-amyloid plaques on the sections of transgenic mouse, and showed high affinity for Aβ(1–42) aggregates (K i =11.1nM and 14.3nM, respectively). Autoradiography in vitro indicated that [99mTc]6 clearly labeled β-amyloid plaques on the sections of transgenic mouse. Biodistribution experiments in normal mice revealed that [99mTc]6 displayed moderate initial brain uptake (0.81% ID/g at 2min), and quickly washed out from the brain (0.25% ID/g at 60min). The preliminary results indicate that the properties of [99mTc]6 are promising, although additional refinements are needed to improve the ability to cross the blood–brain barrier. [Copyright &y& Elsevier]

Abstract: O3 concentration in the stratosphere is decreasing, resulting in higher solar ultraviolet-B radiation (UV-B, 280–320 nm) to the Earth’s surface. Enhanced levels of UV-B radiation may, in turn, alter ecosystem processes such as respiration. In this study, daily changes of ecosystem and soil respiration rates under modulated 20% supplementation of UV-B and ambient UV-B conditions (CK) were investigated in the 2007–08 winter wheat (Triticum aestivum L.) season in a farmland nearing Nanjing city, south-east China, in order to determine the effects of elevated UV-B radiation on these processes. A paired t-test indicated that the effects of elevated UV-B radiation on ecosystem respiration varied across different measuring periods. Significantly lower ecosystem respiration rates in the elevated UV-B plots were found at the later growth (anthesis and beginning grain filling) stages. Elevated UV-B radiation significantly reduced soil respiration rates during each development stages. As far as the whole measuring period is concerned, elevated UV-B radiation significantly (p < 0.05) reduced both ecosystem respiration and soil respiration. The seasonal mean ecosystem respiration rates for the CK and UV-B treatments were 1144.1 and 1008.3 mg CO2 m−2 h−1, respectively, and the seasonal mean soil respiration rates for the two treatments were 286.0 and 249.3 mg CO2 m−2 h−1, respectively. Regression analysis showed that elevated UV-B radiation significantly reduced temperature sensitivity of ecosystem respiration, with the Q 10 decreasing from 1.73 in the CK plots to 1.63 in the elevated UV-B plots. The Q 10 of soil respiration was not significantly affected by enhanced UV-B radiation. The exponential response curve (ecosystem respiration VS temperature) might be constructed with less-damaged plants at the lower temperature and more-damaged plants at the higher temperature, which yielded a lower temperature sensitivity of ecosystem respiration in the UV-B treatment. [Copyright &y& Elsevier]

As the main source of dust in Asia, China often suffers from dust events. The temporal and spatial characteristics of dust events change with the variations of geography, climate and human activities. Based on the criteria of selecting dust events proposed recently by the China Environmental Monitoring Station, the hourly concentration of PM10 and PM2.5 of 336 cities in China from 2015 to 2020 were used to study the temporal and spatial characteristics of dust events more accurately and objectively. The results showed that all of the dust events in China clearly decreased, but the strong dust events did not decrease. There were 334 cities that had dust events except Shenzhen and Dongguan, 299 cities were seriously polluted due to dust events, 134 cities encountered dust level III and 56 cities encountered dust level IV. The high frequencies of dust events were mainly distributed in Northern China, especially in Northwest China. The dust contribution of PM10 to the cities in Northwest China was more than 10% and about 5–10% for PM2.5. The most likely month for dust was May. The starting time of dust was bimodally distributed, and the most common starting time was 10:00–11:00 BJT, followed by 22:00–23:00 BJT. According to the PSCF (Potential Source Contribution Function) results, the dust potential source contribution of different cities mainly came from the northwest, and was mainly affected by Mongolia in addition to the local dust in China. In addition, Beijing was obviously affected by dust recirculation. This study is of great significance to the improvement of the forecast of dust weather and the warning of heavy pollution caused by dust events. [ABSTRACT FROM AUTHOR]

• A model was proposed to evaluate irradiance in irregularly built urban environments. • The proposed model interprets the circumsolar sky radiance by the simple data. • Accuracies of various models were evaluated by data under irregular obstructions. • The proposed model outperformed the classical models in urban environments for HK. The diffuse radiation on building envelopes can be essential to the thermal environment and the energy study of buildings. Because a part of the skydome can be obstructed irregularly in city environments, the diffuse radiance distribution over the skydome should be determined to evaluate the radiation accurately. In this study, this distribution is described by several representative sky directions to specifying the radiance variation features over the skydome, especially the attenuation around the sun. The irradiance of each sky element (normalized by the horizontal diffuse) is correlated to the routine global radiation and the solar altitude as an all-sky model for simple engineering uses. According to two sets of one-month field measurements (in different sites) of the vertical irradiance under irregular obstructions in the hot and humid Hong Kong, the coefficient of determination (R 2) is 0.041 and 0.142 higher than the classical single-direction anisotropic diffuse model that is adopted by many simulation tools, and the R 2 difference can be up to 0.38 for partly cloudy days. When compared to the distribution models, the R 2 outperformance of the proposed model can still be 0.057. The proposed approach is thus effective to the solar radiation studies in the city environments. [ABSTRACT FROM AUTHOR]

Cadherin-5 (CDH5) is aberrantly expressed in a variety of human cancers and plays an important role in angiogenesis. The present study provides further insight into the role of miR-27a-3p in the regulation of CDH5 expression in renal clear cell carcinoma (ccRCC). Thedysregulation of CDH5 expression in ccRCC and its association with clinicopathological characteristics were analyzed using the TCGA database. A meta-analysis was performed to verify the alteration of CDH5 expression in ccRCC using the GEO database. Quantitative RT-PCR and immunohistochemical staining were applied to assess the transcriptional and protein levels of CDH5. TargetScan and Tarbase were employed to predict the miRNAs with the potential to target mRNA of CDH5. The mRNA level of CDH5 in ccRCCwas significantly higher than in normal tissue. CDH5 mRNA expression could therefore serve as a potential diagnostic biomarker for ccRCC (AUC = 0.844). However, the reduced CDH5 transcription levels were significantly correlated with patients in the T3-4 stage, lymph node, and distant metastasis, as well as with a worse clinical outcome. We further observed that CDH5, at the protein level, was almost absent in ccRCC samples. In addition, a few databases screen showed that mir-27a-3p is a highly conserved miRNA targeting CDH5. The expression of mir-27a-3p was significantly elevated in ccRCC tissues in contrast to normal tissues. Importantly, it was positively associated with the T3-4 stage and M stage, respectively, suggesting that the expression level of mir-27a-3p could serve as a diagnostic biomarker for ccRCC (AUC = 0.775). Our data suggest that thereduced translational level of CDH5 in ccRCC was related to the overexpression of mir-27a-3p. The higher mir-27a-3p and lower CDH5 expression significantly correlated with advanced clinical stages for ccRCC patients. [ABSTRACT FROM AUTHOR]

Dust storms have occurred frequently in northwest China and can dramatically reduce visibility and exacerbate air quality in downwind regions through long-range transport. In order to study the distribution characteristics of dust particles sizes, structures and concentrations in the process of dust storm, especially for the vertical distributions, the multi-observation platform composed of six Lidars and nine aerosol analytical instruments is first used to detect a severe dust storm event, which occurred in Northwest China on 3 May 2020. As a strong weather system process, the dust storm has achieved high intensity and wide range. When the intensity of a dust storm is at its strongest, the ratios of PM2.5 (particulate matter with diameter < 2.5 µm) and PM10 (particulate matter with diameter < 10 µm) (PM2.5/PM10) in cities examined were less than 0.2 and the extinction coefficients became greater than 1 km−1 based on Lidar observations. In addition, the growth rates of PM2.5 were higher than that of PM10. The dust particles mainly concentrated at heights of 2 km, after being transported about 200–300 km, vertical height increased by 1–2 km. Meanwhile, the dust concentration decreased markedly. Furthermore, the depolarization ratio showed that dust in the Tengger Desert was dominated by spherical particles. The linear relationships between 532 nm extinction coefficient and the concentration of PM2.5 and PM10 were found firstly and their R2 were 0.706 to 0.987. Our results could give more information for the physical schemes to simulate dust storms in specific models, which could improve the forecast of dust storms. [ABSTRACT FROM AUTHOR]

In previous researches, there are few studies on the mechanisms involved in liquid-liquid doping techniques for preparing oxide particle doped tungsten powders. In this research, based on different polytungstate species, three liquid–liquid doping techniques for synthesizing different doped precursor powders were proposed and compared. The extremely homogeneous hexagonal (NH 4) 0.33 WO 3 ·H 2 O microspheres and flaky (NH 4) 6 H 2 W 12 O 40 ·5H 2 O were synthesized. The synthesis mechanisms of precursors, the doping processes and reaction mechanisms for preparing yttrium-stabilised ZrO 2 in ternary liquid phase system were discussed. The doped powder prepared through azeotropic distillation method exhibits higher quality due to the highly dispersed ZrO 2 (Y) phase uniformly distributed in flaky precursor, and the corresponding alloy possesses more excellent microstructure and mechanical properties. The proposed azeotropic distillation method offers a general pathway and is readily adapted to large-scale industrial production of high-quality oxide particle doped W powders. Image 1 • Three novel liquid–liquid doping technique for preparing precursors were proposed. • Extremely homogeneous microspherical and flaky precursors were synthesized. • Synthesis mechanism of three precursors were investigated in detail, respectively. • Reaction mechanisms for synthesizing cubic ZrO 2 in ternary liquid system were discussed. • Novel method offers a general pathway in industrial production of high quality ODS-W powders. [ABSTRACT FROM AUTHOR]

Selection of appropriate intelligent coatings to protect metallic objects from corrosion is still challenging especially when filler or dispersing materials are used for reinforcing polymer matrix. A novel siloxane corrosion inhibitor precursor was designed and chemically grafted onto the silica nanoparticles to prepare molecular engineered nanofiller (NPInh). The 1H NMR, 13C NMR, FT-IR, TGA and TEM characterization were applied to confirm the successful preparation of NPInh and the grafting amount of corrosion inhibitor precursor onto silica nanoparticles. The surface morphology, dispersion behavior of functionalized nanofiller, mechanical properties and corrosion resistance of the prepared inhibitor functionalized silica nanoparticles with epoxy composites coated on the mild steel were studied. The experimental results indicated the homogeneous dispersion of nanofiller in the epoxy nanocomposite coatings could be enhanced by silica surface modification using inhibitor precursor, and the NPInh component acted as a crucial role in improving the mechanical properties and corrosion resistance of nanocomposite coatings through the combined contribution of mechanical enhancement of nanoparticles and the shielding effect of corrosion inhibitor component. Combining with the apparently optimized strain durability, impact resistance and adhesion strength, the electrochemical measurements showed that the novel epoxy nanocomposite coatings blended with corrosion inhibitor functionalized nanoparticles (NPInh) were capable of superior corrosion resistance with decreased corrosion current (10−10 A/cm2) and a greatly improved protection efficiency (99.9%) after immersion in 3.5 wt% NaCl solution. Moreover, the salt spray durability characterization elucidated that epoxy nanocomposite coating modified with NPInh achieved higher salt spray resistances up to 1000 h. Therefore, it is anticipated that the molecular engineered nanocomposite coatings could open up a new category in the field of corrosion protection by spontaneously improving the dispersity of nanofiller and the barrier effect of coating. • Corrosion inhibitor modified silica nanoparticles were fabricated. • Uniform dispersion of nanofiller and improved film-forming property were obtained through molecular engineering. • Toughening mechanism and shield effect were achieved synchronously to improve the corrosion resistance. • Durability characterization elucidated the potential application of functionalized nanocomposite coating. [ABSTRACT FROM AUTHOR]

Oncol Lett 18: 2394-2403, 2019; DOI: 10.3892/ol.2019.10559 Following the publication of this article, the authors have realized that a couple of errors went unnoticed in the text. These are explained as follows (changes to the printed text are highlighted in bold): In the "Statistical analysis" section, on p. 2396, the 7 SP th sp line, it was incorrectly stated that the RT-qPCR data were analyzed using SPSS 12.0 (SPSS, Inc.); in fact, Prism 5 (GraphPad Software, Inc.) was also used for the statistical treatment of these data. Therefore, the sentence here in its entirety should have read as: "The flow cytometry results were analyzed using FlowJo 10.0.7 software (FlowJo LLC), and the RT-qPCR data was analyzed using B Prism 5 (GraphPad Software, Inc.) b " This error does not affect the results in any way. [Extracted from the article]

Fermentation is considered as one of the most useful biological modification techniques to increase the bioactivity of polysaccharides. In this study, Saccharomyces cerevisiae and Bacillus subtilis were used to ferment wheat bran, and the effects of the fermentation on the structural characteristics and antioxidant activity of wheat bran polysaccharides were investigated. Two polysaccharides were isolated from unfermented and fermented wheat bran and labelled as wheat bran polysaccharides-1 (WBP-1) and fermented wheat bran polysaccharides-1 (FWBP-1), respectively. The results showed fermentation increased the content of total polysaccharides, enhanced the proportions of rhamnose, xylose and arabinose and improved the proportion of fucose to a detectable level. After fermentation, the molecular weight of FWBP-1 (21.19 kDa) was lower than that of WBP-1 (52.02 kDa). In vitro , FWBP-1 exhibited higher reducing power and stronger 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and hydroxyl radical scavenging activities. In zebrafish model, FWBP-1 also displayed superior protective effects against 2,2′-azobis(2-methylpropionamidine) dihydrochloride (AAPH)-induced reactive oxygen species (ROS) production, lipid peroxidation, and cell death. Taken together, S. cerevisiae and B. subtilis fermentation could change the structural characteristics and enhance the antioxidant activity of polysaccharides from wheat bran. Image 1 • Saccharomyces cerevisiae and Bacillus subtilis were used to ferment wheat bran (WB). • Fermentation altered the structural characteristics of WB polysaccharides. • In vitro , fermented-polysaccharides displayed higher reducing power and free radical scavenging activities. • In zebrafish model, fermented-polysaccharides exhibited superior protective effects against AAPH-induced oxidative stress. [ABSTRACT FROM AUTHOR]

A label-free fluorescence method based on self-assembled DNA nanopompom has been developed for miRNA-21 detection. In the presence of miRNA-21, three DNA hairpin probes with split G-quadruplex assemble the DNA nanopompom. Based on the isothermal toehold-mediated DNA strand displacement reaction, the target miRNA can be catalytically recycled and trigger three DNA hairpin probes to self-assemble the DNA nanopompom and release the G-quadruplex. The formation of the G-quadruplex increases the fluorescence emission intensity of thioflavin. For thioflavin-based miRNA-21 detection, the excitation and emission wavelengths are set to 425 nm and 490 nm, respectively. The limit of detection for miRNA-21 is 0.8 pM according to F/F0 = 0.0031 × CmiRNA-21 + 1.0382 (R2 = 0.9978). This sensing system provides a low-cost, effective, and convenient method for miRNA detection, which holds great potential in biochemical diagnosis and clinical practice. [ABSTRACT FROM AUTHOR]

Let G be a maximal plane graph of diameter at most two. Let χ l (G) and χ d (G) denote the list chromatic number and the diagonal chromatic number of G , respectively. In this paper, we study the structure of G and show the following results: (1) χ l (G) ≤ 4; and (2) χ d (G) ≤ 9, and χ d (G) = 9 if and only if G is a specific graph on nine vertices. [ABSTRACT FROM AUTHOR]

Existing clustering algorithms of data gathering in wireless sensor networks neglect the impact of event source on the data spatial correlation. In this article, we proposed a compressed sensing–based dynamic clustering algorithm centred on event source. The main challenges of the prescribed scheme are how to model the impact of event source on spatial correlation and how to obtain the location of event source. To solve both the problems, we first formulate the Euclidean distance spatial correlation model and employ joint sparsity model-1 to describe the impact on the spatial correlation caused by event source. Based on these models, we conceive an efficient clustering scheme, which exploits the compressive data for computing the location of event source and for dynamic clustering. Simulation results show that the proposed compressed sensing–based dynamic clustering algorithm centred on event source outperforms the existing data gathering algorithms in decreasing the communication cost, saving the network energy consumption as well as extending the network survival time under a same accuracy. Additionally, the three performance affecting factors, namely, the attenuation coefficient of event sources, the distance between event sources and the number of event sources, are investigated and provided for constituting the application condition of the compressed sensing–based dynamic clustering algorithm centred on event source. The proposed scheme is potential in large-scale wireless sensor networks such as sensor-based IoT application. [ABSTRACT FROM AUTHOR]