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1. Dissociated Renin – Aldosterone Response to Acute Sodium Depletion in Patients with a Previous History of Pregnancy – Associated Hypertension

Author

Al-Khader Aa, E. H. F. Mcgale, Craven D, and Aber Gm

Subjects
Adult, medicine.medical_specialty, Adolescent, Sodium, Pregnancy Complications, Cardiovascular, Radioimmunoassay, chemistry.chemical_element, Blood Pressure, Plasma renin activity, chemistry.chemical_compound, Pregnancy, Internal medicine, Renin, Renin–angiotensin system, medicine, Humans, Bendroflumethiazide, Aldosterone, business.industry, Body Weight, medicine.disease, Blood pressure, Endocrinology, chemistry, Hypertension, Potassium, Female, business, medicine.drug
Abstract

The effect of sodium depletion on body weight, plasma renin activity (PRA) and plasma aldosterone concentration has been studied in 10 normotensive subjects with a previous history of pregnancy-associated hypertension. The results demonstrate an appropriate increase in PRA but a suppression of plasma aldosterone response to this form of acute sodium depletion. The significance of this dissociated renin-aldosterone response is discussed.

Published
1980
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