310 results on '"Aardema, Marilyn"'
Search Results
2. The Utility of DNA Microarrays for Characterizing Genotoxicity
3. Toxicology and Genetic Toxicology in the New Era of 'Toxicogenomics': Impact of '-omics' Technologies
4. Application of in vitro cell transformation assays in regulatory toxicology for pharmaceuticals, chemicals, food products and cosmetics
5. ECVAM prevalidation study on in vitro cell transformation assays: General outline and conclusions of the study
6. Use of the EpiDermTM 3D reconstructed skin micronucleus assay for fragrance materials
7. A review of mammalian in vivo genotoxicity of hexavalent chromium: implications for oral carcinogenicity risk assessment
8. Workshop summary: Top concentration for in vitro mammalian cell genotoxicity assays; and report from working group on toxicity measures and top concentration for in vitro cytogenetics assays (chromosome aberrations and micronucleus)
9. Improvement of in vivo genotoxicity assessment: Combination of acute tests and integration into standard toxicity testing
10. The reconstructed skin micronucleus assay (RSMN) in EpiDerm™: Detailed protocol and harmonized scoring atlas
11. A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: Genotoxicity. A COLIPA analysis
12. International prevalidation studies of the EpiDerm™ 3D human reconstructed skin micronucleus (RSMN) assay: Transferability and reproducibility
13. An evaluation of 25 selected ToxCast chemicals in medium-throughput assays to detect genotoxicity
14. Integration of Pig-a, micronucleus, chromosome aberration and comet assay endpoints in a 28-day rodent toxicity study with urethane
15. Opportunities to integrate new approaches in genetic toxicology: An ILSI-HESI workshop report
16. Intralaboratory and interlaboratory evaluation of the EpiDerm™ 3D human reconstructed skin micronucleus (RSMN) assay
17. Further development of the EpiDerm™ 3D reconstructed human skin micronucleus (RSMN) assay
18. Evaluation of the genotoxicity of the imidazole antifungal climbazole: Comparison to published results for other azole compounds
19. Emerging approaches in predictive toxicology
20. Achieving professional success in US government, academia, and industry: An EMGS commentary
21. Genetic Toxicology Studies
22. Genetic Toxicology
23. An evaluation of the genotoxicity of the antitussive drug Dextromethorphan
24. Use of the EpiDermTM 3D reconstructed skin micronucleus assay for fragrance materials.
25. Validation of the 3D reconstructed human skin micronucleus (RSMN) assay: an animal-free alternative for following-up positive results from standardin vitrogenotoxicity assays
26. The holy grail in genetic toxicology: Follow-up approaches for positive results in the Ames assay
27. A weight of evidence assessment of the genotoxic potential of 4-methylimidazole as a possible mode of action for the formation of lung tumors in exposed mice
28. How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop
29. Genotoxicity of nanomaterials: Refining strategies and tests for hazard identification
30. Summary of in vitro genetic toxicology assay results: Expected and unexpected effects of recent study design modifications
31. Development of a method for assessing micronucleus induction in a 3D human skin model (EpiDerm™)
32. Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens : II. Further analysis of mammalian cell results, relative predictivity and tumour profiles
33. SFTG international collaborative study on in vitro micronucleus test: III. Using CHO cells
34. SFTG international collaborative study on in vitro micronucleus test: I. General conditions and overall conclusions of the study
35. Cell transformation assays for prediction of carcinogenic potential: state of the science and future research needs
36. New and emerging technologies for genetic toxicity testing
37. In vitro genotoxicity testing using the micronucleus assay in cell lines, human lymphocytes and 3D human skin models
38. Corrigendum to “Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488” [Mutat. Res. 832–833 (2018) 19–28]
39. Corrigendum to “Identifying germ cell mutagens using OECD test guideline 488 (transgenic rodent somatic and germ cell Gene mutation assays) and integration with somatic cell testing.” [Mutat. Res. 832–833 (2018) 7–18]
40. A review of biomonitoring studies measuring genotoxicity in humans exposed to hair dyes
41. Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens: I. Sensitivity, specificity and relative predictivity
42. Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488
43. The In Vitro Micronucleus Assay
44. A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals
45. Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488
46. Identifying germ cell mutagens using OECD test guideline 488 (transgenic rodent somatic and germ cell gene mutation assays) and integration with somatic cell testing
47. Toxicology and genetic toxicology in the new era of “toxicogenomics”: impact of “-omics” technologies
48. Validation of the 3D reconstructed human skin micronucleus (RSMN) assay: an animal-free alternative for following-up positive results from standard in vitro genotoxicity assays.
49. Thresholds in genotoxicity responses
50. Concepts of threshold in mutagenesis and carcinogenesis
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