601 results on '"Aiba, Setsuya"'
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2. An international validation study of the interleukin-2 luciferase leukocyte toxicity test (IL-2 Luc LTT) to evaluate potential immunosuppressive chemicals and its performance after use with the interleukin-2 luciferase assay (IL-2 Luc assay)
3. Functional Analysis of the Transcriptional Regulator IκB-ζ in Intestinal Homeostasis
4. Optimization of the IL-2 Luc assay for immunosuppressive drugs: a novel in vitro immunotoxicity test with high sensitivity and predictivity
5. TLR3 augments glucocorticoid-synthetic enzymes expression in epidermal keratinocytes; Implications of glucocorticoid metabolism in rosacea epidermis
6. An international validation study of the IL-2 Luc assay for evaluating the potential immunotoxic effects of chemicals on T cells and a proposal for reference data for immunotoxic chemicals
7. The IL-1 promoter-driven luciferase reporter cell line THP-G1b can efficiently predict skin-sensitising chemicals
8. The modified IL-8 Luc assay, an in vitro skin sensitisation test, can significantly improve the false-negative judgment of lipophilic sensitizers with logKow values > 3.5
9. TLR3 stimulation induces melanosome endo/phagocytosis through RHOA and CDC42 in human epidermal keratinocyte
10. Facial UV photo imaging for skin pigmentation assessment using conditional generative adversarial networks
11. Androgens modulate keratinocyte differentiation indirectly through enhancing growth factor production from dermal fibroblasts
12. Anti melanogenic effect of Croton roxburghii and Croton sublyratus leaves in α-MSH stimulated B16F10 cells
13. Non-invasive measurement of effective thermal conductivity of human skin with a guard-heated thermistor probe
14. Increased serum production of soluble CD163 and CXCL5 in patients with moyamoya disease: Involvement of intrinsic immune reaction in its pathogenesis
15. In vitro test methods to evaluate the effects of chemicals on innate and adaptive immune responses
16. Epidermal iron metabolism for iron salvage
17. A quantitative analysis of multilineage-differentiating stress-enduring (Muse) cells in human adipose tissue and efficacy of melanocytes induction
18. Costello syndrome model mice with a Hras G12S mutation are susceptible to develop house dust mite-induced atopic dermatitis
19. Increased serum CCL26 level is a potential biomarker for the effectiveness of anti-PD1 antibodies in patients with advanced melanoma
20. Profiling the immunotoxicity of chemicals based on in vitro evaluation by a combination of the Multi-ImmunoTox assay and the IL-8 Luc assay
21. Estrogen receptor β in Merkel cell carcinoma: its possible roles in pathogenesis
22. Tumor-associated macrophages in skin: How to treat their heterogeneity and plasticity
23. Tumor-associated M2 macrophages in mycosis fungoides acquire immunomodulatory function by interferon alpha and interferon gamma
24. Androgen receptor, androgen-producing enzymes and their transcription factors in extramammary Paget disease
25. Optimization of the IL-8 Luc assay as an in vitro test for skin sensitization
26. Steroidogenic enzymes, their related transcription factors and nuclear receptors in human sebaceous glands under normal and pathological conditions
27. Evaluation of the Multi-ImmunoTox Assay composed of 3 human cytokine reporter cells by examining immunological effects of drugs
28. Nonmetal Haptens Induce ATP Release from Keratinocytes through Opening of Pannexin Hemichannels by Reactive Oxygen Species
29. Skin sensitization risk assessment model using artificial neural network analysis of data from multiple in vitro assays
30. First-in-human clinical study of novel technique to diagnose malignant melanoma via thermal conductivity measurements
31. Successful treatment of pustulotic arthro‐osteitis with amoxicillin: A case report and review of the literature.
32. Sweat constitutes several natural moisturizing factors, lactate, urea, sodium, and potassium
33. Functional Melanocytes Are Readily Reprogrammable from Multilineage-Differentiating Stress-Enduring (Muse) Cells, Distinct Stem Cells in Human Fibroblasts
34. In Vivo Imaging Demonstrates ATP Release from Murine Keratinocytes and Its Involvement in Cutaneous Inflammation after Tape Stripping
35. Artificial neural network analysis of data from multiple in vitro assays for prediction of skin sensitization potency of chemicals
36. Enhanced Apoptosis by Disruption of the STAT3-IκB-ζ Signaling Pathway in Epithelial Cells Induces Sjögren’s Syndrome-like Autoimmune Disease
37. Severe erythema exudative multiforme developing from advanced melanoma treated with dabrafenib and trametinib followed by nivolumab
38. Successful control of phototherapy‐resistant lymphomatoid papulosis with oral bexarotene
39. Cytotoxic antimelanoma drugs suppress the activation of M2 macrophages
40. A possible interaction between periostin and CD163+ skin‐resident macrophages in pemphigus vulgaris and bullous pemphigoid
41. Keratoacanthoma, palmoplantar keratoderma developing in an advanced melanoma patient treated with vemurafenib regressed by blockade of mitogen‐activated protein kinase kinase signaling
42. The significance of M1‐polarized CD163+ macrophages in acute graft‐versus‐host disease (GVHD): Possible mechanisms of GVHD in the development of skin lesions.
43. Sex steroid synthesis in human skin in situ: The roles of aromatase and steroidogenic acute regulatory protein in the homeostasis of human skin
44. Epidermal FABP (FABP5) Regulates Keratinocyte Differentiation by 13(S)-HODE-Mediated Activation of the NF-κB Signaling Pathway
45. A synthetic NOD2 agonist, muramyl dipeptide (MDP)-Lys (L18) and IFN-β synergistically induce dendritic cell maturation with augmented IL-12 production and suppress melanoma growth
46. The role of estrogen-metabolizing enzymes and estrogen receptors in human epidermis
47. Nickel differentially regulates NFAT and NF-κB activation in T cell signaling
48. Isolated adrenocorticotropic hormone deficiency possibly caused by nivolumab in a metastatic melanoma patient
49. Receptor activator of nuclear factor kappa-B ligand (RANKL)/RANK signaling promotes cancer-related inflammation through M2 macrophages
50. Bach1-dependent and -independent Regulation of Heme Oxygenase-1 in Keratinocytes
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