142 results on '"Bard R"'
Search Results
2. Measurement of the real dielectric permittivity ϵr of glacial ice
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Allison, P., Archambault, S., Auffenberg, J., Bard, R., Beatty, J.J., Beheler-Amass, M., Besson, D.Z., Beydler, M., Chen, C.C., Chen, C.H., Chen, P., Christenson, A., Clark, B.A., Connolly, A., Cremonesi, L., Deaconu, C., Duvernois, M., Friedman, L., Gaior, R., Hanson, J., Hanson, K., Haugen, J., Hoffman, K.D., Hong, E., Hsu, S.Y., Hu, L., Huang, J.J., Huang, M.-H.A., Ishihara, A., Karle, A., Kelley, J.L., Khandelwal, R., Kim, M.-C., Kravchenko, I., Kruse, J., Kurusu, K., Kuwabara, T., Landsman, H., Latif, U.A., Laundrie, A., Li, C.-J., Liu, T.-C., Lu, M.-Y., Mase, K., Meures, T., Nam, J., Nichol, R.J., Nir, G., Novikov, A., Oberla, E., O’ Murchadha, A., Pan, Y., Pfendner, C., Ratzlaff, K., Relich, M., Roth, J., Sandstrom, P., Seckel, D., Shiao, Y.S., Shultz, A., Song, M., Touart, J., Varner, G.S., Vieregg, A., Wang, M.Z., Wang, S.H., Wissel, S., Yoshida, S., and Young, R.
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- 2019
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3. Criminal Law and Criminology: A Survey of Recent Books
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Ferrall, Bard R.
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- 2005
4. Criminal Law and Criminology: A Survey of Recent Books
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Ferrall, Bard R.
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- 2004
5. Criminal Law and Criminology: A Survey of Recent Books
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Ferrall, Bard R.
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- 2003
6. Criminal Law and Criminology: A Survey of Recent Books
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Ferrall, Bard R.
- Published
- 2002
7. Constraints on the ultra-high-energy neutrino flux from Gamma-Ray bursts from a prototype station of the Askaryan radio array
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Allison, P., Auffenberg, J., Bard, R., Beatty, J.J., Besson, D.Z., Bora, C., Chen, C.-C., Chen, P., Connolly, A., Davies, J.P., DuVernois, M.A., Fox, B., Gorham, P.W., Hanson, K., Hill, B., Hoffman, K.D., Hong, E., Hu, L.-C., Ishihara, A., Karle, A., Kelley, J., Kravchenko, I., Landsman, H., Laundrie, A., Li, C.-J., Liu, T., Lu, M.-Y., Maunu, R., Mase, K., Meures, T., Miki, C., Nam, J., Nichol, R.J., Nir, G., Ó Murchadha, A., Pfendner, C.G., Ratzlaff, K., Rotter, B., Sandstrom, P., Seckel, D., Shultz, A., Song, M., Stockham, J., Stockham, M., Sullivan, M., Touart, J., Tu, H.-Y., Varner, G.S., Yoshida, S., Young, R., Bustamante, M., and Guetta, D.
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- 2017
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8. Criminal Law and Criminology: A Survey of Recent Books
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Ferrall, Bard R.
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- 2001
9. Criminal Law and Criminology: A Survey of Recent Books
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Ferrall, Bard R.
- Published
- 2000
10. Criminal Law and Criminology: A Survey of Recent Books
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Ferrall, Bard R.
- Published
- 1999
11. Criminal Law and Criminology: A Survey of Recent Books
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Ferrall, Bard R.
- Published
- 1998
12. Etiology of Cellulitis and the Validity of New and Old Methods
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Bruun, Trond, Oppegaard, Oddvar, Kittang, Bård R., Mylvaganam, Haima, Langeland, Nina, and Skrede, Steinar
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- 2016
13. First constraints on the ultra-high energy neutrino flux from a prototype station of the Askaryan Radio Array
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Allison, P., Auffenberg, J., Bard, R., Beatty, J.J., Besson, D.Z., Bora, C., Chen, C.-C., Chen, P., Connolly, A., Davies, J.P., DuVernois, M.A., Fox, B., Gorham, P.W., Hanson, K., Hill, B., Hoffman, K.D., Hong, E., Hu, L.-C., Ishihara, A., Karle, A., Kelley, J., Kravchenko, I., Landsman, H., Laundrie, A., Li, C.-J., Liu, T., Lu, M.-Y., Maunu, R., Mase, K., Meures, T., Miki, C., Nam, J., Nichol, R.J., Nir, G., O’Murchadha, A., Pfendner, C.G., Ratzlaff, K., Richman, M., Rotter, B., Sandstrom, P., Seckel, D., Shultz, A., Stockham, J., Stockham, M., Sullivan, M., Touart, J., Tu, H.-Y., Varner, G.S., Yoshida, S., and Young, R.
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- 2015
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14. Clinical characteristics, treatment, and outcomes for elderly patients in a dedicated Covid-19 ward at a primary health care facility in western Norway: a retrospective observational study
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Bård Reiakvam Kittang, Ane Tveiten Øien, Einar Engtrø, Marian Skjellanger, and Kjell Krüger
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Covid-19 ,Nursing home ,Advance care planning ,Palliative care ,Clinical Frailty Scale ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background The coronavirus pandemic has hit the oldest and frailest individuals hard, particularly patients and residents in nursing homes. In March 2020, we established a Covid-19 ward at a nursing home in Bergen, western Norway for elderly patients with Sars-CoV-2 infection and in the need of treatment and care in a primary health care facility. The aims of this study were to describe the organization of the ward, the clinical outcomes of infection, treatment, mortality rates in the population, the level of advanced care planning, and end-of-life care for those who died. Methods We present patient characteristics, outcomes, vaccination status, treatment, decisions regarding treatment intensity upon clinical deterioration, and mortality for the patients in the ward. Clinical factors possibly related to a fatal outcome were analysed with chi square test (categorical variables) or t-test (continuous variables). Results 257 patients were included from March 2020 to April 2022. Fifty-nine patients (23.0%) developed respiratory failure. Ten patients (3.9%) were admitted to hospital. Advance care planning was undertaken for 245 (95.3%) of the patients. 30-day mortality rate decreased from 42 to 4% during the study period. Of the 29 (11.3%) patients who died, all were well alleviated in the terminal phase, and 26 (89.7%) of them had a Clinical Frailty Scale (CFS) value ≥ 7. A high score for CFS, respiratory failure and respiratory co-infection were significantly associated with Covid-19 related death within 30 days. Conclusions Covid-19-related mortality markedly decreased during the study period, and a high score for CFS was related to a fatal outcome. Thorough planning of treatment intensity upon deterioration, low hospitalization rates, and good relief for those who died suggest that dedicated Covid-19 wards in nursing homes can provide good treatment for the patients and relieve other nursing homes and specialist health care services.
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- 2024
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15. Streptokinase reduces Streptococcus dysgalactiae subsp. equisimilis biofilm formation
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Lea A. Tölken, Janine V. Neufend, Oddvar Oppegaard, Karen Methling, Kirsten Moll, Sylvio Redanz, Miriam M.D. Katsburg, Murtadha Q. Ali, Patience Shumba, Bernd Kreikemeyer, Steinar Skrede, Marcus Fulde, Anna Norrby-Teglund, Michael Lalk, Bård R. Kittang, and Nikolai Siemens
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Streptococcus dysgalactiae subsp. equisimilis ,Biofilm ,Streptokinase ,Necrotizing soft tissue infections ,Microbiology ,QR1-502 - Abstract
Abstract Background Streptococcus dysgalactiae subspecies equisimilis (SDSE) is increasingly recognized as an emerging cause of invasive diseases including necrotizing soft tissue infections (NSTIs). In contrast to the closely related Streptococcus pyogenes, SDSE infections mainly affect older and comorbid patients. Biofilm formation has been demonstrated in soft tissue biopsies of S. pyogenes NSTI cases. Results Here, we show that bacterial aggregations indicative of biofilms are also present in SDSE NSTI. Although streptokinase (Ska) activity and biofilm formation did not correlate in a diverse set of clinical SDSE isolates, addition of exogenous Ska at an early time point prevented biofilm formation for selected strains. Deletion of ska in SDSE S118 strain resulted in increased biofilm forming capacity. Ska-deficient mutant strain was characterized by a higher metabolic activity and consequent metabolome profiling of biofilms identified higher deposition of a wide range of metabolites as compared to the wild-type. Conclusions Our results argue that Ska suppresses biofilm formation in SDSE independent of its original plasminogen converting activity. However, the impact of biofilms and its consequences for patient outcomes in streptococcal NSTIs remain to be elucidated.
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- 2024
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16. 'What if the patient has a severe reaction, and it is my fault?' A qualitative study exploring factors for sustainable implementation of penicillin allergy delabelling
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Marie Bjørbak Alnæs, Brita Skodvin, Jan Anker Jahnsen, Grete Kalleklev Velure, Oddvar Oppegaard, Bård Reiakvam Kittang, Torgeir Storaas, and Margrethe Aase Schaufel
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Penicillin allergy delabelling ,Nurse ,Doctor ,Facilitators ,Barriers ,Focus group interview ,Infectious and parasitic diseases ,RC109-216 - Abstract
Abstract Background Penicillin allergy delabelling (PAD), the process of evaluating penicillin allergy labels, is a key target in antibiotic stewardship, but uptake of the procedure outside clinical studies is limited. We aimed to explore factors that need to be addressed to sustainably implement a clinical pathway for PAD. Methods We conducted a qualitative study based on semi-structured interviews with focus groups consisting of a purposive sample of twenty-five nurses and physicians working in four different hospitals in Western Norway. Systematic text condensation was applied for analysis. Results Psychological safety was reported as crucial for clinicians to perform PAD. A narrative of uncertainty and anticipated negative outcomes were negatively associated with PAD performance. Education, guidelines, and colleague- and leadership support could together create psychological safety and empower health personnel to perform PAD. Key factors for sustainable implementation of PAD were facilitating the informant’s profound motivation for providing optimal health care and for reducing antimicrobial resistance. Informants were motivated by the prospect of a simplified PAD procedure. We identified three main needs for implementation of PAD: (1) creating psychological safety; (2) utilising clinicians’ inherent motivation and (3) optimal organisational structures. Conclusion A planned implementation of PAD must acknowledge clinicians’ need for psychological safety and aid reassurance through training, leadership, and guidelines. To implement PAD as an everyday practice it must be minimally disruptive and provide a contextually adaptive logistic chain. Also, the clinician’s motivation for providing the best possible healthcare should be utilised to aid implementation. The results of this study will aid sustainable implementation of PAD in Norway. Ethics The study was approved by the Western Norway Regional Committee for Medical Research Ethics (Study No:199210).
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- 2024
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17. Transfemoral hepatic vein access in double vein embolization – initial experience and feasibility
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Ulrik Carling, Sigurd Berger, Eyvind Gjønnæss, Bård Røsok, Sheraz Yaqub, Kristoffer Lassen, Åsmund Avdem Fretland, and Eric Dorenberg
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Double vein embolization ,Liver augmentation ,Liver hyperthrophy ,Portal vein embolization ,Post hepatectomy liver failure ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Background Hepatic vein embolization in double vein embolization (DVE) can be performed with transhepatic, transjugular or transfemoral access. This study evaluates the feasibility and technical success of using a transfemoral access for the hepatic vein embolization in patients undergoing preoperative to induce hypertrophy of the future liver remnant (FLR). Material and methods Retrospective analysis of single center cohort including 17 consecutive patients. The baseline standardized FLR was 18.2% (range 14.7–24.9). Portal vein embolization was performed with vascular plugs and glue through an ipsilateral transhepatic access. Hepatic vein embolization was performed using vascular plugs. Access for the hepatic vein was either transhepatic, transjugular or transfemoral. Technical success, number of hepatic veins embolized and complications were registered. In addition, volumetric data including degree of hypertrophy (DH) and kinetic growth rate (KGR), and resection data were registered. R: Seven of the 17 patients had transfemoral hepatic vein embolization, with 100% technical success. No severe complications were registered. In the whole cohort, the median number of hepatic veins embolized was 2 (1–6). DH was 8.6% (3.0–19.4) and KGR was 3.6%/week (1.4–7.4), without significant differences between the patients having transfemoral versus transhepatic /transjugular access (p = 0.48 and 0.54 respectively). Time from DVE to surgery was median 4.8 weeks (2.6–33.9) for the whole cohort, with one patient declining surgery, two having explorative laparotomy and one patient having change of surgical strategy due to insufficient growth. Conclusion Transfemoral access is a feasible option with a high degree of technical success for hepatic vein embolization in patients with small future liver remnants needing DVE.
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- 2024
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18. Epidemiological and microbial trends of infective endocarditis in western Norway: a 7-year prospective observational study
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Stina Jordal, Øyvind Kommedal, Rune Haaverstad, Sahrai Saeed, Einar Skulstad Davidsen, Pirjo-Riitta Salminen, Karl Ove Hufthammer, and Bård Reiakvam Kittang
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Infective endocarditis ,Staphylococcus aureus ,Enterococci ,Prosthetic material ,Infectious and parasitic diseases ,RC109-216 - Abstract
Abstract Background In this prospective, observational study, we aimed to investigate epidemiologic and microbial trends of infective endocarditis in western Norway. Methods Clinical and microbiological characteristics of 497 cases of infective endocarditis from 2016 through 2022 were investigated. Categorical data were analysed using Chi-squared tests. Survival data were analysed using multiple Cox regression and reported using hazard ratios. Results The mean age was 67 years, and 74% were men. The annual incidence rates varied from 10.4 to 14.1 per 100,000 inhabitants per year. Infective endocarditis on native valves was observed in 257 (52%) of the cases, whereas infective endocarditis on prosthetic valves and/or cardiac implantable electronic devices was observed in 240 (48%) of the cases: infection on surgically implanted bioprostheses was observed in 124 (25%) of the patients, infection on transcatheter aortic valve implantation was observed in 47 (10%) patients, and infection on mechanical valves was observed in 34 (7%) cases. Infection related to cardiac implantable electronic devices was observed in a total of 50 (10%) cases. Staphylococcus aureus and viridans streptococci were the most common microbial causes, and isolated in 145 (29%) and 130 (26%) of the cases, respectively. Enterococcal endocarditis showed a rising trend during the study period and constituted 90 (18%) of our total cases of infective endocarditis, and 67%, 47%, and 26% of the cases associated with prosthetic material, transcatheter aortic valve implantation and cardiac implantable electronic devices, respectively. There was no significant difference in 90-day mortality rates between the native valve endocarditis group (12%) and the group with infective endocarditis on prosthetic valves or cardiac implants (14%), p = 0.522. In a model with gender, age, people who inject drugs, microbiology and type of valve affected, only advanced age was significantly associated with fatal outcome within 90 days. Conclusions The incidence of infective endocarditis, and particularly enterococcal endocarditis, increased during the study period. Enterococci appeared to have a particular affinity for prosthetic cardiac material. Advanced age was the only independent risk factor for death within 90 days.
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- 2024
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19. Design and initial performance of the Askaryan Radio Array prototype EeV neutrino detector at the South Pole
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Allison, P., Auffenberg, J., Bard, R., Beatty, J.J., Besson, D.Z., Böser, S., Chen, C., Chen, P., Connolly, A., Davies, J., DuVernois, M., Fox, B., Gorham, P.W., Grashorn, E.W., Hanson, K., Haugen, J., Helbing, K., Hill, B., Hoffman, K.D., Hong, E., Huang, M., Huang, M.H.A., Ishihara, A., Karle, A., Kennedy, D., Landsman, H., Liu, T.C., Macchiarulo, L., Mase, K., Meures, T., Meyhandan, R., Miki, C., Morse, R., Newcomb, M., Nichol, R.J., Ratzlaff, K., Richman, M., Ritter, L., Rott, C., Rotter, B., Sandstrom, P., Seckel, D., Touart, J., Varner, G.S., Wang, M.-Z., Weaver, C., Wendorff, A., Yoshida, S., and Young, R.
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- 2012
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20. Comment mesurer le retentissement d’un traitement en situation écologique par une évaluation fiable de la fonction manuelle chez les enfants présentant une atteinte unilatérale : le Assisting Hand Assessment (AHA)
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Romein, E. and Bard, R.
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- 2010
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21. Upper limb assessment in children with cerebral palsy: Translation and reliability of the French version for the Melbourne unilateral upper limb assessment ( test de Melbourne)
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Bard, R., Chaléat-Valayer, E., Combey, A., Bleu, P.E., Perretant, I., and Bernard, J.-C.
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- 2009
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22. Federal University-Laboratory
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Shellabarger, Claire J., Platt, William J., Fain, John N., Bard, R. C., and Weinberg, Alvin M.
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- 1962
23. Correction: Areas of consensus on unwarranted and warranted transfers between nursing homes and emergency care facilities in Norway: a Delphi study
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Arne Bastian Wiik, Malcolm Bray Doupe, Marit Stordal Bakken, Bård Reiakvam Kittang, Frode Fadnes Jacobsen, and Oddvar Førland
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Public aspects of medicine ,RA1-1270 - Published
- 2024
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24. Muscle assessment in healthy teenagers: Comparison with teenagers with low back pain
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Bernard, J.-C., Bard, R., Pujol, A., Combey, A., Boussard, D., Begue, C., and Salghetti, A.M.
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- 2008
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25. Évaluation musculaire de l’adolescent sain. Comparaison avec une population d’adolescents lombalgiques
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Bernard, J.-C., Bard, R., Pujol, A., Combey, A., Boussard, D., Begue, C., and Salghetti, A.-M.
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- 2008
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26. Areas of consensus on unwarranted and warranted transfers between nursing homes and emergency care facilities in Norway: a Delphi study
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Arne Bastian Wiik, Malcolm Bray Doupe, Marit Stordal Bakken, Bård Reiakvam Kittang, Frode Fadnes Jacobsen, and Oddvar Førland
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Delphi study ,Emergency care ,Nursing home ,Patient Transfer ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Transferring residents from nursing homes (NHs) to emergency care facilities (ECFs) is often questioned as many are terminally ill and have access to onsite care. While some NH to ECF transfers have merit, avoiding other transfers may benefit residents and reduce healthcare system costs and provider burden. Despite many years of research in this area, differentiating warranted (i.e., appropriate) from unwarranted NH to ECF transfers remains challenging. In this article, we report consensus on warranted and unwarranted NH to ECF transfers scenarios. Methods A Delphi study was used to identify consensus regarding warranted and unwarranted NH to ECF transfers. Delphi participants included nurses (RNs) and medical doctors (MDs) from NHs, out-of-hours primary care clinics (OOHs), and hospital-based emergency departments. A list of 12 scenarios and 11 medical conditions was generated from the existing literature on causes and medical conditions leading to transfers, and pilot tested and refined prior to conducting the study. Three Delphi rounds were conducted, and data were analyzed using descriptive and comparative statistics. Results Seventy-nine experts consented to participate, of whom 56 (71%) completed all three Delphi rounds. Participants reached high or very high consensus on when to not transfer residents, except for scenarios regarding delirium, where only moderate consensus was attained. Conversely, except when pain relieving surgery was required, participants reached low agreement on scenarios depicting warranted NH to ECF transfers. Consensus opinions differ significantly between health professionals, participant gender, and rurality, for seven of the 23 transfer scenarios and medical conditions. Conclusions Transfers from nursing homes to emergency care facilities can be defined as warranted, discretionary, and unwarranted. These categories are based on the areas of consensus found in this Delphi study and are intended to operationalize the terms warranted and unwarranted transfers between nursing homes and emergency care facilities.
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- 2024
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27. The CMS barrel calorimeter response to particle beams from 2 to 350 GeV/c
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Abdullin, S., Abramov, V., Acharya, B., Adam, N., Adams, M., Adzic, P., Akchurin, N., Akgun, U., Albayrak, E., Alemany-Fernandez, R., Almeida, N., Anagnostou, G., Andelin, D., Anderson, E. W., Anfreville, M., Anicin, I., Antchev, G., Antunovic, Z., Arcidiacono, R., Arenton, M. W., Auffray, E., Argiro, S., Askew, A., Atramentov, O., Ayan, S., Arcidy, M., Aydin, S., Aziz, T., Baarmand, M., Babich, K., Baccaro, S., Baden, D., Baffioni, S., Bakirci, M. N., Balazs, M., Banerjee, Sud., Banerjee, Sun., Bard, R., Barge, D., Barnes, V., Barney, D., Barone, L., Bartoloni, A., Baty, C., Bawa, H., Baiatian, G., Bandurin, D., Beauceron, S., Bell, K. W., Bencze, G., Benetta, R., Bercher, M., Beri, S., Bernet, C., Berntzon, L., Berthon, U., Besancon, M., Betev, B., Beuselinck, R., Bhatnagar, V., Bhatti, A., Biino, C., Blaha, J., Bloch, P., Blyth, S., Bodek, A., Bornheim, A., Bose, S., Bose, T., Bourotte, J., Brett, A. M., Brown, R. M., Britton, D., Budd, H., Buehler, M., Burchesky, K., Busson, P., Camanzi, B., Camporesi, T., Cankoçak, K., Carrell, K., Carrera, E., Cartiglia, N., Cavallari, F., Cerci, S., Cerutti, M., Chang, P., Chang, Y. H., Charlot, C., Chen, E. A., Chen, W. T., Chen, Z., Chendvankar, S., Chipaux, R., Choudhary, B. C., Choudhury, R. K., Chung, Y., Clarida, W., Cockerill, D. J. A., Combaret, C., Conetti, S., Cossutti, F., Cox, B., Cremaldi, L., Cushman, P., Cussans, D. G., Dafinei, I., Damgov, J., Da Silva Di Calafiori, D. R., Daskalakis, G., Davatz, G., David, A., de Barbaro, P., Debbins, P., Deiters, K., Dejardin, M., Djordjevic, M., Deliomeroglu, M., Della Negra, R., Della Ricca, G., Del Re, D., Demianov, A., De Min, A., Denegri, D., Depasse, P., de Visser, T., Descamps, J., Deshpande, P. V., Diaz, J., Diemoz, M., Di Marco, E., Dimitrov, L., Dissertori, G., Dittmar, M., Djambazov, L., Dobrzynski, L., Drndarevic, S., Duboscq, J. E., Dugad, S., Dumanoglu, I., Duru, F., Dutta, D., Dzelalija, M., Efthymiopoulos, I., Elias, J., Elliott-Peisert, A., El Mamouni, H., Elvira, D., Emeliantchik, I., Eno, S., Ershov, A., Erturk, S., Esen, S., Eskut, E., Evangelou, I., Evans, D. L., Fabbro, B., Faure, J. L., Fay, J., Fenyvesi, A., Ferri, F., Fisher, W., Flower, P. S., Franci, D., Franzoni, G., Freeman, J., Freudenreich, K., Funk, W., Ganjour, S., Gargiulo, C., Gascon, S., Gataullin, M., Gaultney, V., Gamsizkan, H., Gavrilov, V., Geerebaert, Y., Genchev, V., Gentit, F. X., Gerbaudo, D., Gershtein, Y., Ghezzi, A., Ghodgaonkar, M. D., Gilly, J., Givernaud, A., Gleyzer, S., Gninenko, S., Go, A., Gobbo, B., Godinovic, N., Golubev, N., Golutvin, I., Goncharov, P., Gong, D., Govoni, P., Grant, N., Gras, P., Grassi, T., Green, D., Greenhalgh, R. J. S., Gribushin, A., Grinev, B., Guevara Riveros, L., Guillaud, J. P., Gurtu, A., Murat Güler, A., Gülmez, E., Gümüş, K., Haelen, T., Hagopian, S., Hagopian, V., Haguenauer, M., Halyo, V., Hamel de Monchenault, G., Hansen, M., Hashemi, M., Hauptman, J., Hazen, E., Heath, H. F., Heering, A., Heister, A., Heltsley, B., Hill, J. A., Hintz, W., Hirosky, R., Hobson, P. R., Honma, A., Hou, G. W. S., Hsiung, Y., Hunt, A., Husejko, M., Ille, B., Ilyina, N., Imlay, R., Ingram, D., Ingram, Q., Isiksal, E., Jarry, P., Jarvis, C., Jeong, C., Jessop, C., Johnson, K., Jones, J., Jovanovic, D., Kaadze, K., Kachanov, V., Kaftanov, V., Kailas, S., Kalagin, V., Kalinin, A., Kalmani, S., Karmgard, D., Kataria, S. K., Kaur, M., Kaya, M., Kaya, O., Kayis-Topaksu, A., Kellogg, R., Kennedy, B. W., Khmelnikov, A., Kim, H., Kisselevich, I., Kloukinas, K., Kodolova, O., Kohli, J., Kokkas, P., Kolberg, T., Kolossov, V., Korablev, A., Korneev, Y., Kosarev, I., Kramer, L., Krasnikov, N., Krinitsyn, A., Krokhotin, A., Krpic, D., Kryshkin, V., Kubota, Y., Kubrik, A., Kuleshov, S., Kumar, A., Kumar, P., Kunori, S., Kuo, C. M., Kurt, P., Kyberd, P., Kyriakis, A., Laasanen, A., Ladygin, V., Laird, E., Landsberg, G., Laszlo, A., Lawlor, C., Lazic, D., Lebeau, M., Lecomte, P., Lecoq, P., Ledovskoy, A., Lee, S.-W., Leshev, G., Lethuillier, M., Levchuk, L., Lin, S. W., Lin, W., Linn, S., Lintern, A. L., Litvine, V., Litvintsev, D., Litov, L., Lobolo, L., Locci, E., Lodge, A. B., Longo, E., Loukas, D., Los, S., Lubinsky, V., Luckey, P. D., Lukanin, V., Lustermann, W., Lynch, C., Ma, Y., Machado, E., Mahlke-Krueger, H., Maity, M., Majumder, G., Malberti, M., Malclès, J., Maletic, D., Mandjavidze, I., Mans, J., Manthos, N., Maravin, Y., Marchica, C., Marinelli, N., Markou, A., Markou, C., Marlow, D., Markowitz, P., Marone, M., Martinez, G., Mathez, H., Matveev, V., Mavrommatis, C., Maurelli, G., Mazumdar, K., Meridiani, P., Merlo, J. P., Mermerkaya, H., Mescheryakov, G., Mestvirishvili, A., Mikhailin, V., Milenovic, P., Miller, M., Milleret, G., Miné, P., Moeller, A., Mohammadi-Najafabadi, M., Mohanty, A. K., Moissenz, P., Mondal, N., Moortgat, F., Mossolov, V., Mur, M., Musella, P., Musienko, Y., Nagaraj, P., Nardulli, A., Nash, J., Nedelec, P., Negri, P., Newman, H. B., Nikitenko, A., Norbeck, E., Nessi-Tedaldi, F., Obertino, M. M., Olson, J., Onel, Y., Onengut, G., Organtini, G., Orimoto, T., Ozkan, C., Ozkurt, H., Ozkorucuklu, S., Ozok, F., Paganoni, M., Paganini, P., Paktinat, S., Pal, A., Palma, A., Panev, B., Pant, L., Papadakis, A., Papadakis, I., Papadopoulos, I., Paramatti, R., Parracho, P., Pastrone, N., Patil, M., Patterson, J. R., Pauss, F., Penzo, A., Petrakou, E., Petrushanko, S., Petrosyan, A., Phillips, II, D. G., Pikalov, V., Piperov, S., Piroué, P., Podrasky, V., Polatoz, A., Pompos, A., Popescu, S., Posch, C., Pozdnyakov, A., Ptochos, F., Puljak, I., Pullia, A., Punz, T., Puzovic, J., Qian, W., Ragazzi, S., Rahatlou, S., Ralich, R. M., Rande, J., Razis, P. A., Redaelli, N., Reddy, L., Reidy, J., Renker, D., Reucroft, S., Reymond, J. M., Ribeiro, P., Roeser, U., Rogalev, E., Rogan, C., Roh, Y., Rohlf, J., Romanteau, T., Rondeaux, F., Ronquest, M., Ronzhin, A., Rosowsky, A., Rovelli, C., Ruchti, R., Rumerio, P., Rusack, R., Rusakov, S. V., Ryan, M. J., Ryazanov, A., Safronov, G., Sala, L., Salerno, R., Sanders, D. A., Santanastasio, F., Sanzeni, C., Sarycheva, L., Satyanarayana, B., Schinzel, D., Schmidt, I., Seez, C., Sekmen, S., Semenov, S., Senchishin, V., Sergeyev, S., Serin, M., Sever, R., Sharp, P., Shepherd-Themistocleous, C. H., Siamitros, C., Sillou, D., Singh, J. B., Singovsky, A., Sirois, Y., Sirunyan, A., Silva, J., Silva, P., Skuja, A., Sharma, S., Sherwood, B., Shiu, J. G., Shivpuri, R. K., Shukla, P., Shumeiko, N., Smirnov, V., Smith, B. J., Smith, V. J., Sogut, K., Sonmez, N., Sorokin, P., Spezziga, M., Sproston, M., Stefanovich, R., Stöckli, F., Stolin, V., Sudhakar, K., Sulak, L., Suter, H., Suzuki, I., Swain, J., Tabarelli de Fatis, T., Talov, V., Takahashi, M., Tcheremoukhine, A., Teller, O., Teplov, K., Theofilatos, K., Thiebaux, C., Thomas, R., Timciuc, V., Timlin, C., Titov, M., Tobias, A., Tonwar, S., Topakli, H., Topkar, A., Triantis, F. A., Troshin, S., Tully, C., Turchanovich, L., Tyurin, N., Ueno, K., Ulyanov, A., Uzunian, A., Vanini, A., Vankov, I., Vardanyan, I., Varela, F., Varela, J., Vasil’ev, A., Velasco, M., Vergili, M., Verma, P., Verrecchia, P., Vesztergombi, G., Veverka, J., Vichoudis, P., Vidal, R., Virdee, T., Vishnevskiy, A., Vlassov, E., Vodopiyanov, I., Volobouev, I., Volkov, A., Volodko, A., Von Gunten, H. P., Wang, L., Wang, M., Wardrope, D., Weber, M., Weng, J., Werner, J., Wetstein, M., Winn, D., Wigmans, R., Williams, J. H., Whitmore, J., Won, S., Wu, S. X., Yang, Y., Yaselli, I., Yazgan, E., Yetkin, T., Yohay, R., Zabi, A., Zalan, P., Zamiatin, N., Zarubin, A., Zelepoukine, S., Zeyrek, M., Zhang, J., Zhang, L. Y., Zhu, K., and CMS HCAL/ECAL Collaborations
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- 2009
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28. Design, performance, and calibration of the CMS hadron-outer calorimeter
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Abdullin, S., Abramov, V., Acharya, B., Adam, N., Adams, M., Akchurin, N., Akgun, U., Albayrak, E., Anderson, E. W., Antchev, G., Arcidy, M., Ayan, S., Aydin, S., Aziz, T., Baarmand, M., Babich, K., Baden, D., Bakirci, M. N., Banerjee, Sudeshna, Banerjee, Sunanda, Bard, R., Barnes, V., Bawa, H., Baiatian, G., Bencze, G., Beri, S., Berntzon, L., Bhandari, V., Bhatnagar, V., Bhatti, A., Bodek, A., Bose, S., Bose, T., Budd, H., Burchesky, K., Camporesi, T., Cankoçak, K., Carrell, K., Cerci, S., Chendvankar, S., Chung, Y., Clarida, W., Cremaldi, L., Cushman, P., Damgov, J., de Barbaro, P., Debbins, P., Deliomeroglu, M., Demianov, A., de Visser, T., Deshpande, P. V., Diaz, J., Dimitrov, L., Dugad, S., Dumanoglu, I., Duru, F., Efthymiopoulos, I., Elias, J., Elvira, D., Emeliantchik, I., Eno, S., Ershov, A., Erturk, S., Esen, S., Eskut, E., Fenyvesi, A., Fisher, W., Freeman, J., Ganguli, S. N., Gaultney, V., Gamsizkan, H., Gavrilov, V., Genchev, V., Gleyzer, S., Golutvin, I., Goncharov, P., Grassi, T., Green, D., Gribushin, A., Grinev, B., Guchait, M., Gurtu, A., Murat Güler, A., Gülmez, E., Gümüş, K., Haelen, T., Hagopian, S., Hagopian, V., Halyo, V., Hashemi, M., Hauptman, J., Hazen, E., Heering, A., Heister, A., Hunt, A., Ilyina, N., Ingram, D., Isiksal, E., Jarvis, C., Jeong, C., Johnson, K., Jones, J., Kaftanov, V., Kalagin, V., Kalinin, A., Kalmani, S., Karmgard, D., Kaur, M., Kaya, M., Kaya, O., Kayis-Topaksu, A., Kellogg, R., Khmelnikov, A., Kim, H., Kisselevich, I., Kodolova, O., Kohli, J., Kolossov, V., Korablev, A., Korneev, Y., Kosarev, I., Kramer, L., Krinitsyn, A., Krishnaswamy, M. R., Krokhotin, A., Kryshkin, V., Kuleshov, S., Kumar, A., Kunori, S., Laasanen, A., Ladygin, V., Laird, E., Landsberg, G., Laszlo, A., Lawlor, C., Lazic, D., Lee, S. W., Levchuk, L., Linn, S., Litvintsev, D., Lobolo, L., Los, S., Lubinsky, V., Lukanin, V., Ma, Y., Machado, E., Maity, M., Majumder, G., Mans, J., Marlow, D., Markowitz, P., Martinez, G., Mazumdar, K., Merlo, J. P., Mermerkaya, H., Mescheryakov, G., Mestvirishvili, A., Miller, M., Moeller, A., Mohammadi-Najafabadi, M., Moissenz, P., Mondal, N., Mossolov, V., Nagaraj, P., Narasimham, V. S., Norbeck, E., Olson, J., Onel, Y., Onengut, G., Ozkan, C., Ozkurt, H., Ozkorucuklu, S., Ozok, F., Paktinat, S., Pal, A., Patil, M., Penzo, A., Petrushanko, S., Petrosyan, A., Pikalov, V., Piperov, S., Podrasky, V., Polatoz, A., Pompos, A., Popescu, S., Posch, C., Pozdnyakov, A., Qian, W., Ralich, R. M., Reddy, L., Reidy, J., Rogalev, E., Roh, Y., Rohlf, J., Ronzhin, A., Ruchti, R., Ryazanov, A., Safronov, G., Sanders, D. A., Sanzeni, C., Sarycheva, L., Satyanarayana, B., Schmidt, I., Sekmen, S., Semenov, S., Senchishin, V., Sergeyev, S., Serin, M., Sever, R., Singh, B., Singh, J. B., Sirunyan, A., Skuja, A., Sharma, S., Sherwood, B., Shumeiko, N., Smirnov, V., Sogut, K., Sonmez, N., Sorokin, P., Spezziga, M., Stefanovich, R., Stolin, V., Sudhakar, K., Sulak, L., Suzuki, I., Talov, V., Teplov, K., Thomas, R., Tonwar, S., Topakli, H., Tully, C., Turchanovich, L., Ulyanov, A., Vanini, A., Vankov, I., Vardanyan, I., Varela, F., Vergili, M., Verma, P., Vesztergombi, G., Vidal, R., Vishnevskiy, A., Vlassov, E., Vodopiyanov, I., Volobouev, I., Volkov, A., Volodko, A., Wang, L., Werner, J., Wetstein, M., Winn, D., Wigmans, R., Whitmore, J., Wu, S. X., Yazgan, E., Yetkin, T., Zalan, P., Zarubin, A., Zeyrek, M., and CMS HCAL Collaborations
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- 2008
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29. Design, performance, and calibration of CMS hadron-barrel calorimeter wedges
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Abdullin, S., Abramov, V., Acharya, B., Adams, M., Akchurin, N., Akgun, U., Anderson, E.W., Antchev, G., Ayan, S., Aydin, S., Baarmand, M., Baden, D., Banerjee, Sud., Banerjee, Sun., Bard, R., Barnes, V., Bawa, H., Baiatian, G., Bencze, G., Beri, S., Bhatnagar, V., Bodek, A., Budd, H., Burchesky, K., Camporesi, T., Cankoçak, K., Carrell, K., Chendvankar, S., Chung, Y., Cremaldi, L., Cushman, P., Damgov, J., de Barbaro, P., Demianov, A., de Visser, T., Dimitrov, L., Dugad, S., Dumanoglu, I., Duru, F., Elias, J., Elvira, D., Emeliantchik, I., Eno, S., Ershov, A., Eskut, E., Fisher, W., Freeman, J., Gavrilov, V., Genchev, V., Gershtein, Y., Golutvin, I., Goncharov, P., Grassi, T., Green, D., Gribushin, A., Grinev, B., Gülmez, E., Gümüş, K., Haelen, T., Hagopian, S., Hagopian, V., Hauptman, J., Hazen, E., Heering, A., Imboden, M., Isiksal, E., Jarvis, C., Johnson, K., Kaftanov, V., Kalagin, V., Karmgard, D., Kalmani, S., Katta, S., Kaur, M., Kaya, M., Kayis-Topaksu, A., Kellogg, R., Khmelnikov, A., Kisselevich, I., Kodolova, O., Kohli, J., Kolossov, V., Korablev, A., Korneev, Y., Kosarev, I., Krinitsyn, A., Krokhotin, A., Kryshkin, V., Kuleshov, S., Kumar, A., Kunori, S., Polatoz, A., Laasanen, A., Lawlor, C., Lazic, D., Levchuk, L., Litvintsev, D., Litov, L., Los, S., Lubinsky, V., Lukanin, V., Machado, E., Mans, J., Massolov, V., Mazumdar, K., Merlo, J.P., Mescheryakov, G., Mestvirishvili, A., Miller, M., Mondal, N., Nagaraj, P., Norbeck, E., O’Dell, V., Olson, J., Onel, Y., Onengut, G., Ozdes-Koca, N., Ozkorucuklu, S., Ozok, F., Paktinat, S., Patil, M., Petrushanko, S., Pikalov, V., Piperov, S., Podrasky, V., Pompos, A., Posch, C., Qian, W., Ralich, R., Reddy, L., Reidy, J., Ruchti, R., Rohlf, J., Ronzhin, A., Ryazanov, A., Sanders, D.A., Sanzeni, C., Sarycheva, L., Satyanarayana, B., Schmidt, I., Senchishin, V., Sergeyev, S., Serin-Zeyrek, M., Sever, R., Singh, J., Sirunyan, A., Skuja, A., Sherwood, B., Shumeiko, N., Smirnov, V., Sorokin, P., Stefanovich, R., Stolin, V., Sudhakar, K., Suzuki, I., Talov, V., Thomas, R., Tully, C., Turchanovich, L., Ulyanov, A., Vankov, I., Vardanyan, I., Verma, P., Vesztergombi, G., Vidal, R., Vlassov, E., Vodopiyanov, I., Volkov, A., Volodko, A., Winn, D., Whitmore, J., Wu, S.X., Zalan, P., Zarubin, A., Zeyrek, M., and The CMS-HCAL Collaboration
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- 2008
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30. Design, performance, and calibration of CMS forward calorimeter wedges
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Abdullin, S., Abramov, V., Acharya, B., Adams, M., Akchurin, N., Akgun, U., Anderson, E.W., Antchev, G., Arcidy, M., Ayan, S., Aydin, S., Baarmand, M., Babich, K., Baden, D., Bakirci, M.N., Banerjee, Sud., Banerjee, Sun., Bard, R., Barnes, V., Bawa, H., Baiatian, G., Bencze, G., Beri, S., Bhatnagar, V., Bodek, A., Budd, H., Burchesky, K., Camporesi, T., Cankoçak, K., Carrell, K., Cerci, S., Chendvankar, S., Chung, Y., Cremaldi, L., Cushman, P., Damgov, J., de Barbaro, P., Deliomeroglu, M., Demianov, A., de Visser, T., Dimitrov, L., Dindar, K., Dugad, S., Dumanoglu, I., Duru, F., Elias, J., Elvira, D., Emeliantchik, I., Eno, S., Eskut, E., Fenyvesi, A., Fisher, W., Freeman, J., Gamsizkan, H., Gavrilov, V., Genchev, V., Gershtein, Y., Golutvin, I., Goncharov, P., Grassi, T., Green, D., Gribushin, A., Grinev, B., Gülmez, E., Gümüş, K., Haelen, T., Hagopian, S., Hagopian, V., Hashemi, M., Hauptman, J., Hazen, E., Heering, A., Ilyina, N., Isiksal, E., Jarvis, C., Johnson, K., Kaftanov, V., Kalagin, V., Kalinin, A., Karmgard, D., Kalmani, S., Katta, S., Kaur, M., Kaya, M., Kayis-Topaksu, A., Kellogg, R., Khmelnikov, A., Kim, H., Kisselevich, I., Kodolova, O., Kohli, J., Kolossov, V., Korablev, A., Korneev, Y., Kosarev, I., Koylu, S., Kramer, L., Krinitsyn, A., Krokhotin, A., Kryshkin, V., Kuleshov, S., Kumar, A., Kunori, S., Kurt, P., Kuzucu-Polatoz, A., Laasanen, A., Ladygin, V., Laszlo, A., Lawlor, C., Lazic, D., Levchuk, L., Linn, S., Litvintsev, D., Litov, L., Los, S., Lubinsky, V., Lukanin, V., Ma, Y., Machado, E., Mans, J., Markowitz, P., Massolov, V., Martinez, G., Mazumdar, K., Merlo, J.P., Mermerkaya, H., Mescheryakov, G., Mestvirishvili, A., Miller, M., Mohammadi-Najafabadi, M., Moissenz, P., Mondal, N., Nagaraj, P., Norbeck, E., Olson, J., Onel, Y., Onengut, G., Ozdes-Koca, N., Ozkan, C., Ozkurt, H., Ozkorucuklu, S., Paktinat, S., Pal, A., Patil, M., Penzo, A., Petrushanko, S., Petrosyan, A., Pikalov, V., Piperov, S., Podrasky, V., Pompos, A., Posch, C., Qiang, W., Reddy, L., Reidy, J., Ruchti, R., Rogalev, E., Rohlf, J., Ronzhin, A., Ryazanov, A., Safronov, G., Sanders, D.A., Sanzeni, C., Sarycheva, L., Satyanarayana, B., Schmidt, I., Sekmen, S., Semenov, S., Senchishin, V., Sergeyev, S., Serin-Zeyrek, M., Sever, R., Singh, J., Sirunyan, A., Skuja, A., Sharma, S., Sherwood, B., Shumeiko, N., Smirnov, V., Sogut, K., Sorokin, P., Spezziga, M., Stefanovich, R., Stolin, V., Sulak, L., Suzuki, I., Talov, V., Teplov, K., Thomas, R., Topakli, H., Tully, C., Turchanovich, L., Ulyanov, A., Vankov, I., Vardanyan, I., Varela, F., Vergili, M., Verma, P., Vesztergombi, G., Vidal, R., Vishnevskiy, A., Vlassov, E., Vodopiyanov, I., Volkov, A., Volodko, A., Wang, L., Wetstein, M., Winn, D., Wigmans, R., Whitmore, J., Wu, S.X., Yazgan, E., Yershov, A., Yetkin, T., Zalan, P., Zarubin, A., Zeyrek, M., and The CMS-HCAL Collaboration
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- 2008
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31. Antimicrobial resistance patterns in Streptococcus dysgalactiae in a One Health perspective
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Marte Glambek, Steinar Skrede, Audun Sivertsen, Bård Reiakvam Kittang, Alba Kaci, Christine Monceyron Jonassen, Hannah Joan Jørgensen, Norwegian Study Group on Streptococcus dysgalactiae, and Oddvar Oppegaard
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Streptococcus dysgalactiae ,antibiotic resistance ,One Health ,whole genomic sequencing ,horizontal genetic transfer ,animal ,Microbiology ,QR1-502 - Abstract
BackgroundStreptococcus dysgalactiae (SD) is an important pathogen in humans as well as in a broad range of animal species. Escalating rates of antibiotic resistance in SD has been reported in both human and veterinary clinical practice, but the dissemination of resistance determinants has so far never been examined in a One Health Perspective. We wanted to explore the occurrence of zoonotic transmission of SD and the potential for exchange of resistance traits between SD from different host populations.MethodsWe compared whole genome sequences and phenotypical antimicrobial susceptibility of 407 SD isolates, comprising all isolates obtained from human bloodstream infections in 2018 (n = 274) and available isolates associated with animal infections from the years 2018 and 2019 (n = 133) in Norway.ResultsAntimicrobial resistance genes were detected in 70 (26%), 9 (25%) and 2 (2%) of the isolates derived from humans, companion animals and livestock, respectively. Notably, distinct host associated genotypic resistomes were observed. The erm(A) gene was the dominant cause of erythromycin resistance in human associated isolates, whereas only erm(B) and lsa(C) were identified in SD isolates from animals. Moreover, the tetracycline resistance gene tet(O) was located on different mobile genetic elements in SD from humans and animals. Evidence of niche specialization was also evident in the phylogenetic analysis, as the isolates could be almost perfectly delineated in accordance with host species. Nevertheless, near identical mobile genetic elements were observed in four isolates from different host species including one human, implying potential transmission of antibiotic resistance between different environments.ConclusionWe found a phylogenetic delineation of SD strains in line with host adapted populations and niche specialization. Direct transmission of strains or genetic elements carrying resistance genes between SD from different ecological niches appears to be rare in our geographical region.
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- 2024
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32. Discontinuation of imatinib in patients with oligometastatic gastrointestinal stromal tumour who are in complete radiological remission: a prospective multicentre phase II study
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Ivar Hompland, KJetil Boye, Anne Marit Wiedswang, Andri Papakonstantinou, Bård Røsok, Heikki Joensuu, and Øyvind Bruland
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Gastrointestinal stromal tumour ,GIST ,imatinib ,Oligometastatic disease ,Survival ,Quality of Life ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Introduction: Metastatic gastrointestinal stromal tumour (GIST) is considered incurable, and life-long treatment with tyrosine kinase inhibitors is recommended. We investigated whether selected patients with metastatic GIST may remain in durable remission despite imatinib discontinuation. Patients: In this 1-group, prospective, multicentre phase II trial selected patients with oligometastatic (≤3 metastases) GIST discontinued imatinib treatment. Eligible patients had been treated with imatinib >5 years without progression and had no radiologically detectable metastases after metastasectomy, radiofrequency ablation (RFA) or complete response to imatinib. The primary endpoint was progression-free survival (PFS) 3-years after stopping imatinib. Overall survival (OS) and quality of life (QoL) were secondary endpoints. Results: The trial closed prematurely due to slow accrual. Between January 5, 2017, and June 5, 2019, 13 patients were enrolled, of whom 12 discontinued imatinib. The median follow-up time was 55 months (range, 36 to 69) after study entry. Five (42%) of the 12 eligible patients remained progression free, and seven (58%) progressed with a median time to progression 10 months. Median PFS was 23 months and the estimated 3-year PFS 41%. Six of the seven patients who progressed restarted imatinib, and all six responded. Three-year OS was 100%, and all patients were alive at the time of the study analysis. QoL measured 5 and 11 months after discontinuation of imatinib demonstrated improvement compared to the baseline. Interpretation: A substantial proportion of selected patients with oligometastatic GIST treated with imatinib and metastasis surgery/RFA may remain disease-free for ≥3 years with improved QoL after stopping of imatinib.
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- 2024
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33. Pancreatic duct occlusion with polychloroprene-based glue for the management of postoperative pancreatic fistula after pancreatoduodenectomy—an outdated approach?
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Sheraz Yaqub, Bård Røsok, Ivar Prydz Gladhaug, and Knut Jørgen Labori
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duct occlusion ,postoperative pancreatic fistula ,pancreatoduodenectomy ,pancreatic surgery ,reoperation ,Surgery ,RD1-811 - Abstract
BackgroundManaging postoperative pancreatic fistula (POPF) presents a formidable challenge after pancreatoduodenectomy. Some centers consider pancreatic duct occlusion (PDO) in reoperations following pancreatoduodenectomy as a pancreas-preserving procedure, aiming to control a severe POPF. The aim of the current study was to evaluate the short- and long-term outcomes of employing PDO for the management of the pancreatic stump during relaparotomy for POPF subsequent to pancreatoduodenectomy.MethodsRetrospective review of consecutive patients at Oslo University Hospital undergoing pancreatoduodenectomy and PDO during relaparotomy. Pancreatic stump management during relaparotomy consisted of occlusion of the main pancreatic duct with polychloroprene Faxan-Latex, after resecting the dehiscent jejunal loop previously constituting the pancreaticojejunostomy.ResultsBetween July 2005 and September 2015, 826 pancreatoduodenectomies were performed. Overall reoperation rate was 13.2% (n = 109). POPF grade B/C developed in 113 (13.7%) patients. PDO during relaparotomy was performed in 17 (2.1%) patients, whereas completion pancreatectomy was performed in 22 (2.7%) patients. Thirteen (76%) of the 17 patients had a persistent POPF after PDO, and the time from PDO until removal of the last abdominal drain was median 35 days. Of the PDO patients, 13 (76%) patients required further drainage procedures (n = 12) or an additional reoperation (n = 1). In-hospital mortality occurred in one patient (5.9%). Five (29%) patients developed new-onset diabetes mellitus, and 16 (94%) patients acquired exocrine pancreatic insufficiency.ConclusionsPDO is a safe and feasible approach for managing severe POPF during reoperation following pancreatoduodenectomy. A significant proportion of patients experience persistent POPF post-procedure, necessitating supplementary drainage interventions. The findings suggest that it is advisable to explore alternative pancreas-preserving methods before opting for PDO in the management of POPF subsequent to pancreatoduodenectomy.
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- 2024
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34. Évaluation du résultat d'un corset monocoque carbone respectant la respiration (CMCR) dans la scoliose idiopathique chez l'enfant et l'adolescent : étude rétrospective sur 115 patients
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Bernard, J.-C., Jemni, S., Schneider, M., Boussard, D., Saillard, V., Bard, R., Lecante, C., Barral, F., Berne, G., Pourret, S., Mulatier, A., and Notin, G.
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- 2005
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35. Reservist Reaction
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Bard, R. C., Tassinari, S. J., Mirarchi, Anthony O., Geiser, S. W., and Wilber, Charles G.
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- 1952
36. Radioactive source calibration technique for the CMS hadron calorimeter
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Hazen, E, Lawlor, C, Rohlf, J.W, Wu, S.X, Baumbaugh, A, Elias, J.E, Freeman, J, Green, D, Lazic, D, Los, S, Ronzhin, A, Sergueev, S, Shaw, T, Vidal, R, Whitmore, J, Zimmerman, T, Adams, M, Burchesky, K, Qian, W, Baden, A, Bard, R, Breden, H, Grassi, T, Skuja, A, Fisher, W, Mans, J, Tully, C, Barnes, V, Laasanen, A, de Barbaro, P, and Budd, H
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- 2003
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37. The B AB AR detector
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Aubert, B., Bazan, A., Boucham, A., Boutigny, D., De Bonis, I., Favier, J., Gaillard, J.-M., Jeremie, A., Karyotakis, Y., Le Flour, T., Lees, J.P., Lieunard, S., Petitpas, P., Robbe, P., Tisserand, V., Zachariadou, K., Palano, A., Chen, G.P., Chen, J.C., Qi, N.D., Rong, G., Wang, P., Zhu, Y.S., Eigen, G., Reinertsen, P.L., Stugu, B., Abbott, B., Abrams, G.S., Amerman, L., Borgland, A.W., Breon, A.B., Brown, D.N., Button-Shafer, J., Clark, A.R., Dardin, S., Day, C., Dow, S.F., Fan, Q., Gaponenko, I., Gill, M.S., Goozen, F.R., Gowdy, S.J., Gritsan, A., Groysman, Y., Hernikl, C., Jacobsen, R.G., Jared, R.C., Kadel, R.W., Kadyk, J., Karcher, A., Kerth, L.T., Kipnis, I., Kluth, S., Kral, J.F., Lafever, R., LeClerc, C., Levi, M.E., Lewis, S.A., Lionberger, C., Liu, T., Long, M., Luo, L., Lynch, G., Luft, P., Mandelli, E., Marino, M., Marks, K., Matuk, C., Meyer, A.B., Minor, R., Mokhtarani, A., Momayezi, M., Nyman, M., Oddone, P.J., Ohnemus, J., Oshatz, D., Patton, S., Pedrali-Noy, M., Perazzo, A., Peters, C., Pope, W., Pripstein, M., Quarrie, D.R., Rasson, J.E., Roe, N.A., Romosan, A., Ronan, M.T., Shelkov, V.G., Stone, R., Strother, P.D., Telnov, A.V., von der Lippe, H., Weber, T.F., Wenzel, W.A., Zizka, G., Bright-Thomas, P.G., Hawkes, C.M., Kirk, A., Knowles, D.J., O'Neale, S.W., Watson, A.T., Watson, N.K., Deppermann, T., Koch, H., Krug, J., Kunze, M., Lewandowski, B., Peters, K., Schmuecker, H., Steinke, M., Andress, J.C., Barlow, N.R., Bhimji, W., Chevalier, N., Clark, P.J., Cottingham, W.N., De Groot, N., Dyce, N., Foster, B., Mass, A., McFall, J.D., Wallom, D., Wilson, F.F., Abe, K., Hearty, C., McKenna, J.A., Thiessen, D., Camanzi, B., Harrison, T.J., McKemey, A.K., Tinslay, J., Antohin, E.I., Blinov, V.E., Bukin, A.D., Bukin, D.A., Buzykaev, A.R., Dubrovin, M.S., Golubev, V.B., Ivanchenko, V.N., Kolachev, G.M., Korol, A.A., Kravchenko, E.A., Mikhailov, S.F., Onuchin, A.P., Salnikov, A.A., Serednyakov, S.I., Skovpen, Yu.I., Telnov, V.I., Yushkov, A.N., Booth, J., Lankford, A.J., Mandelkern, M., Pier, S., Stoker, D.P., Zioulas, G., Ahsan, A., Arisaka, K., Buchanan, C., Chun, S., Faccini, R., MacFarlane, D.B., Prell, S.A., Rahatlou, Sh., Raven, G., Sharma, V., Burke, S., Callahan, D., Campagnari, C., Dahmes, B., Hale, D., Hart, P.A., Kuznetsova, N., Kyre, S., Levy, S.L., Long, O., Lu, A., May, J., Richman, J.D., Verkerke, W., Witherell, M., Yellin, S., Beringer, J., DeWitt, J., Dorfan, D.E., Eisner, A.M., Frey, A., Grillo, A.A., Grothe, M., Heusch, C.A., Johnson, R.P., Kroeger, W., Lockman, W.S., Pulliam, T., Rowe, W., Sadrozinski, H., Schalk, T., Schmitz, R.E., Schumm, B.A., Seiden, A., Spencer, E.N., Turri, M., Walkowiak, W., Wilder, M., Williams, D.C., Chen, E., Dubois-Felsmann, G.P., Dvoretskii, A., Hanson, J.E., Hitlin, D.G., Kolomensky, Yu.G., Metzler, S., Oyang, J., Porter, F.C., Ryd, A., Samuel, A., Weaver, M., Yang, S., Zhu, R.Y., Devmal, S., Geld, T.L., Jayatilleke, S., Jayatilleke, S.M., Mancinelli, G., Meadows, B.T., Sokoloff, M.D., Bloom, P., Broomer, B., Erdos, E., Fahey, S., Ford, W.T., Gaede, F., van Hoek, W.C., Johnson, D.R., Michael, A.K., Nauenberg, U., Olivas, A., Park, H., Rankin, P., Roy, J., Sen, S., Smith, J.G., Wagner, D.L., Blouw, J., Harton, J.L., Krishnamurthy, M., Soffer, A., Toki, W.H., Warner, D.W., Wilson, R.J., Zhang, J., Brandt, T., Brose, J., Dahlinger, G., Dickopp, M., Dubitzky, R.S., Eckstein, P., Futterschneider, H., Kocian, M.L., Krause, R., Müller-Pfefferkorn, R., Schubert, K.R., Schwierz, R., Spaan, B., Wilden, L., Behr, L., Bernard, D., Bonneaud, G.R., Brochard, F., Cohen-Tanugi, J., Ferrag, S., Fouque, G., Gastaldi, F., Matricon, P., Mora de Freitas, P., Renard, C., Roussot, E., T'Jampens, S., Thiebaux, C., Vasileiadis, G., Verderi, M., Anjomshoaa, A., Bernet, R., Di Lodovico, F., Muheim, F., Playfer, S., Swain, J.E., Falbo, M., Bozzi, C., Dittongo, S., Folegani, M., Piemontese, L., Ramusino, A.C., Treadwell, E., Anulli, F., Baldini-Ferroli, R., Calcaterra, A., de Sangro, R., Falciai, D., Finocchiaro, G., Patteri, P., Peruzzi, I.M., Piccolo, M., Xie, Y., Zallo, A., Bagnasco, S., Buzzo, A., Contri, R., Crosetti, G., Fabbricatore, P., Farinon, S., Lo Vetere, M., Macri, M., Minutoli, S., Monge, M.R., Musenich, R., Pallavicini, M., Parodi, R., Passaggio, S., Pastore, F.C., Patrignani, C., Pia, M.G., Priano, C., Robutti, E., Santroni, A., Bartoldus, R., Dignan, T., Hamilton, R., Mallik, U., Cochran, J., Crawley, H.B., Fischer, P.A., Lamsa, J., McKay, R., Meyer, W.T., Rosenberg, E.I., Albert, J.N., Beigbeder, C., Benkebil, M., Breton, D., Cizeron, R., Du, S., Grosdidier, G., Hast, C., Höcker, A., Lacker, H.M., LePeltier, V., Lutz, A.M., Plaszczynski, S., Schune, M.H., Trincaz-Duvoid, S., Truong, K., Valassi, A., Wormser, G., Alford, O., Behne, D., Bionta, R.M., Bowman, J., Brigljević, V., Brooks, A., Dacosta, V.A., Fackler, O., Fujino, D., Harper, M., Lange, D.J., Mugge, M., O'Connor, T.G., Olson, H., Ott, L., Parker, E., Pedrotti, B., Roeben, M., Shi, X., van Bibber, K., Wenaus, T.J., Wright, D.M., Wuest, C.R., Yamamoto, B., Carroll, M., Cooke, P., Fry, J.R., Gabathuler, E., Gamet, R., George, M., Kay, M., McMahon, S., Muir, A., Payne, D.J., Sloane, R.J., Sutcliffe, P., Touramanis, C., Aspinwall, M.L., Bowerman, D.A., Dauncey, P.D., Eschrich, I., Gunawardane, N.J.W., Martin, R., Nash, J.A., Price, D.R., Sanders, P., Smith, D., Azzopardi, D.E., Back, J.J., Dixon, P., Harrison, P.F., Newman-Coburn, D., Potter, R.J.L., Shorthouse, H.W., Williams, M.I., Vidal, P.B., Cowan, G., George, S., Green, M.G., Kurup, A., Marker, C.E., McGrath, P., McMahon, T.R., Salvatore, F., Scott, I., Vaitsas, G., Brown, D., Davis, C.L., Li, Y., Pavlovich, J., Allison, J., Barlow, R.J., Boyd, J.T., Fullwood, J., Jackson, F., Khan, A., Lafferty, G.D., Savvas, N., Simopoulos, E.T., Thompson, R.J., Weatherall, J.H., Bard, R., Dallapiccola, C., Farbin, A., Jawahery, A., Lillard, V., Olsen, J., Roberts, D.A., Schieck, J.R., Blaylock, G., Flood, K.T., Hertzbach, S.S., Kofler, R., Lin, C.S., Willocq, S., Wittlin, J., Brau, B., Cowan, R., Taylor, F., Yamamoto, R.K., Britton, D.I., Fernholz, R., Houde, M., Milek, M., Patel, P.M., Trischuk, J., Lanni, F., Palombo, F., Bauer, J.M., Booke, M., Cremaldi, L., Kroeger, R., Reep, M., Reidy, J., Sanders, D.A., Summers, D.J., Arguin, J.F., Beaulieu, M., Martin, J.P., Nief, J.Y., Seitz, R., Taras, P., Woch, A., Zacek, V., Nicholson, H., Sutton, C.S., Cartaro, C., Cavallo, N., De Nardo, G., Fabozzi, F., Gatto, C., Lista, L., Piccolo, D., Sciacca, C., Cason, N.M., LoSecco, J.M., Alsmiller, J.R.G., Gabriel, T.A., Handler, T., Heck, J., Iwasaki, M., Sinev, N.B., Caracciolo, R., Colecchia, F., Dal Corso, F., Galeazzi, F., Marzolla, M., Michelon, G., Morandin, M., Posocco, M., Rotondo, M., Santi, S., Simonetto, F., Stroili, R., Torassa, E., Voci, C., Bailly, P., Benayoun, M., Briand, H., Chauveau, J., David, P., De la Vaissière, C., Del Buono, L., Genat, J.-F., Hamon, O., Leruste, Ph., Le Diberder, F., Lebbolo, H., Lory, J., Martin, L., Martinez-Vidal, F., Roos, L., Stark, J., Versillé, S., Zhang, B., Manfredi, P.F., Ratti, L., Re, V., Speziali, V., Frank, E.D., Gladney, L., Guo, Q.H., Panetta, J.H., Angelini, C., Batignani, G., Bettarini, S., Bondioli, M., Bosi, F., Carpinelli, M., Forti, F., Gaddi, A., Gagliardi, D., Giorgi, M.A., Lusiani, A., Mammini, P., Morganti, M., Morsani, F., Neri, N., Profeti, A., Paoloni, E., Raffaelli, F., Rama, M., Rizzo, G., Sandrelli, F., Simi, G., Triggiani, G., Haire, M., Judd, D., Paick, K., Turnbull, L., Wagoner, D.E., Albert, J., Bula, C., Kelsey, M.H., Lu, C., McDonald, K.T., Miftakov, V., Sands, B., Schaffner, S.F., Smith, A.J.S., Tumanov, A., Varnes, E.W., Bronzini, F., Buccheri, A., Bulfon, C., Cavoto, G., del Re, D., Ferrarotto, F., Ferroni, F., Fratini, K., Lamanna, E., Leonardi, E., Mazzoni, M.A., Morganti, S., Piredda, G., Safai Tehrani, F., Serra, M., Voena, C., Waldi, R., Jacques, P.F., Kalelkar, M., Plano, R.J., Adye, T., Claxton, B., Dowdell, J., Egede, U., Franek, B., Galagedera, S., Geddes, N.I., Gopal, G.P., Kay, J., Lidbury, J., Madani, S., Metcalfe, S., Markey, G., Olley, P., Watt, M., Xella, S.M., Aleksan, R., Besson, P., Bourgeois, P., Convert, P., De Domenico, G., de Lesquen, A., Emery, S., Gaidot, A., Ganzhur, S.F., Georgette, Z., Gosset, L., Graffin, P., Hamel de Monchenault, G., Hervé, S., Karolak, M., Kozanecki, W., Langer, M., London, G.W., Marques, V., Mayer, B., Micout, P., Mols, J.P., Mouly, J.P., Penichot, Y., Rolquin, J., Serfass, B., Toussaint, J.C., Usseglio, M., Vasseur, G., Yeche, C., Zito, M., Copty, N., Purohit, M.V., Yumiceva, F.X., Adam, I., Adesanya, A., Anthony, P.L., Aston, D., Bartelt, J., Becla, J., Bell, R., Bloom, E., Boeheim, C.T., Boyarski, A.M., Boyce, R.F., Briggs, D., Bulos, F., Burgess, W., Byers, B., Calderini, G., Chestnut, R., Claus, R., Convery, M.R., Coombes, R., Cottrell, L., Coupal, D.P., Coward, D.H., Craddock, W.W., DeBarger, S., DeStaebler, H., Dorfan, J., Doser, M., Dunwoodie, W., Dusatko, J.E., Ecklund, S., Fieguth, T.H., Freytag, D.R., Glanzman, T., Godfrey, G.L., Haller, G., Hanushevsky, A., Harris, J., Hasan, A., Hee, C., Himel, T., Huffer, M.E., Hung, T., Innes, W.R., Jessop, C.P., Kawahara, H., Keller, L., King, M.E., Klaisner, L., Krebs, H.J., Langenegger, U., Langeveld, W., Leith, D.W.G.S., Louie, S.K., Luitz, S., Luth, V., Lynch, H.L., McDonald, J., Manzin, G., Marsiske, H., Mattison, T., McCulloch, M., McDougald, M., McShurley, D., Menke, S., Messner, R., Morii, M., Mount, R., Muller, D.R., Nelson, D., Nordby, M., O'Grady, C.P., Olavson, L., O'Neill, F.G., Oxoby, G., Paolucci, P., Pavel, T., Perl, J., Pertsova, M., Petrak, S., Putallaz, G., Raines, P.E., Ratcliff, B.N., Reif, R., Robertson, S.H., Rochester, L.S., Roodman, A., Russel, J.J., Sapozhnikov, L., Saxton, O.H., Schietinger, T., Schindler, R.H., Schwiening, J., Sciolla, G., Seeman, J.T., Serbo, V.V., Shapiro, S., Skarpass Sr, K., Snyder, A., Soderstrom, E., Soha, A., Spanier, S.M., Stahl, A., Stiles, P., Su, D., Sullivan, M.K., Talby, M., Tanaka, H.A., Va'vra, J., Wagner, S.R., Wang, R., Weber, T., Weinstein, A.J.R., White, J.L., Wienands, U., Wisniewski, W.J., Young, C.C., Yu, N., Burchat, P.R., Cheng, C.H., Kirkby, D., Meyer, T.I., Roat, C., Henderson, R., Khan, N., Berridge, S., Bugg, W., Cohn, H., Hart, E., Weidemann, A.W., Benninger, T., Izen, J.M., Kitayama, I., Lou, X.C., Turcotte, M., Bianchi, F., Bona, M., Daudo, F., Di Girolamo, B., Gamba, D., Grosso, P., Smol, A., Trapani, P.P., Zanin, D., Bosisio, L., Della Ricca, G., Lanceri, L., Pompili, A., Poropat, P., Prest, M., Rashevskaia, I., Vallazza, E., Vuagnin, G., Panvini, R.S., Brown, C., De Silva, A., Kowalewski, R., Pitman, D., Roney, J.M., Band, H.R., Charles, E., Dasu, S., Elmer, P., Johnson, J.R., Nielsen, J., Orejudos, W., Pan, Y., Prepost, R., Scott, I.J., Walsh, J., Wu, S.L., Yu, Z., Zobernig, H., Moore, T.B., and Neal, H.
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- 2002
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38. SARS-CoV-2 specific immune responses in overweight and obese COVID-19 patients
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Therese Bredholt Onyango, Fan Zhou, Geir Bredholt, Karl A. Brokstad, Sarah Lartey, Kristin G.-I. Mohn, Türküler Özgümüs, Bård Reiakvam Kittang, Dagrun Waag Linchausen, Shahin Shafiani, Rebecca Elyanow, Bjørn Blomberg, Nina Langeland, Rebecca Jane Cox, Bergen COVID-19 Research Group, Amit Bansal, Anders Madsen, Camilla Tøndel, Elisabeth Berg Fjelltveit, Hanne Søyland, Helene Heitmann Sandnes, Jan Stefan Olofsson, Juha Vahokoski, Kristin Risa, Lena Hansen, Mai-Chi Trieu, Marianne Sævik, and Nina Urke Ertesvåg
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COVID-19 ,obesity ,overweight ,spike ,neutralising ,cellular ,Immunologic diseases. Allergy ,RC581-607 - Abstract
Obesity is a known risk factor for severe respiratory tract infections. In this prospective study, we assessed the impact of being obese or overweight on longitudinal SARS-CoV-2 humoral and cellular responses up to 18 months after infection. 274 patients provided blood samples at regular time intervals up to 18 months including obese (BMI ≥30, n=32), overweight (BMI 25-29.9, n=103) and normal body weight (BMI 18.5-24.9, n=134) SARS-CoV-2 patients. We determined SARS-CoV-2 spike-specific IgG, IgA, IgM levels by ELISA and neutralising antibody titres by neutralisation assay. RBD- and spike-specific memory B cells were investigated by ELISpot, spike- and non-spike-specific IFN-γ, IL-2 and IFN-γ/IL-2 secreting T cells by FluoroSpot and T cell receptor (TCR) sequencing was performed. Higher BMI correlated with increased COVID-19 severity. Humoral and cellular responses were stronger in overweight and obese patients than normal weight patients and associated with higher spike-specific IgG binding titres relative to neutralising antibody titres. Linear regression models demonstrated that BMI, age and COVID-19 severity correlated independently with higher SARS-CoV-2 immune responses. We found an increased proportion of unique SARS-CoV-2 specific T cell clonotypes after infection in overweight and obese patients. COVID-19 vaccination boosted humoral and cellular responses irrespective of BMI, although stronger immune boosting was observed in normal weight patients. Overall, our results highlight more severe disease and an over-reactivity of the immune system in overweight and obese patients after SARS-CoV-2 infection, underscoring the importance of recognizing overweight/obese individuals as a risk group for prioritisation for COVID-19 vaccination.
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- 2023
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39. A new pathway for penicillin delabeling in Norway
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Marie Bjørbak Alnæs, MD, Oddvar Oppegaard, PhD, Bård Reiakvam Kittang, PhD, Stein Håkon Låstad Lygre, PhD, Anine Bernhoft Langeland, CNS, Brita Skodvin, PhD, Tormod Bjånes, PhD, and Torgeir Storaas, PhD
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Critical pathway ,Drug hypersensitivity ,Penicillins ,Immunologic diseases. Allergy ,RC581-607 - Abstract
Background: Penicillin allergy is self-reported by 3–10% of patients admitted to hospital. The label is wrong in 90% of the cases and has severe health implications. Penicillin-delabeling can reverse the negative effects of the label, and pathways adapted to local practice are needed. No tools are available in Norway for penicillin delabeling outside an allergy clinic. Objective: To create and validate the first penicillin delabeling pathway applicable outside an allergy clinic in Norway. Methods: An interdisciplinary taskforce created a penicillin allergy delabeling program (PAD) adapted to the Norwegian health care system. This was validated in a prospective, single-center study. Very low-risk and low-risk patients underwent a direct oral penicillin challenge and high-risk patients were referred for allergologic evaluation. Results: One-hundred forty-nine patients declaring penicillin allergy were included. Seventy-four (50%) were very-low- and low risk patients suitable for a direct oral penicillin challenge resulting in only 1 mild reaction. Sixty high-risk patients were eligible for an oral penicillin challenge after allergologic evaluation; 3 patients reacted non-severely. Conclusion: We have created and demonstrated feasibility of the first penicillin delabeling program (PAD) applicable in a hospital setting outside an allergy clinic in Norway. Our data suggest this is safe and beneficial, with 49% patients delabeled through a direct oral penicillin challenge, performed without any serious adverse events, and an overall 87% delabeling rate.
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- 2023
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40. Streptococcus dysgalactiae Bloodstream Infections, Norway, 1999–2021
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Oddvar Oppegaard, Marte Glambek, Dag Harald Skutlaberg, Steinar Skrede, Audun Sivertsen, and Bård Reiakvam Kittang
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Streptococcus dysgalactiae ,bacteria ,streptococci ,beta-hemolytic streptococcus ,bloodstream infections ,epidemiology ,Medicine ,Infectious and parasitic diseases ,RC109-216 - Abstract
Streptococcus dysgalactiae increasingly is recognized as a pathogen of concern for human health. However, longitudinal surveillance data describing temporal trends of S. dysgalactiae are scarce. We retrospectively identified all β-hemolytic streptococcal bloodstream infections reported in Bergen, in western Norway, during 1999–2021. To explore S. dysgalactiae disease burden in a broader context, we mapped the incidence of all microbial species causing bloodstream infections during 2012–2021. We found S. dysgalactiae incidence rates substantially increased during the study period; by 2021, S. dysgalactiae was the fifth most common pathogen causing bloodstream infections in our region. We noted genotypic shifts and found that the rising trend was related in part to the introduction and expansion of the stG62647 emm-type. S. dysgalactiae is among the most common causes of bloodstream infections in western Norway, and increased surveillance and unambiguous species identification are needed to monitor the disease burden attributable to this pathogen.
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- 2023
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41. Technetium-99m antimony sulphide colloid lymphoscintigraphy of the prostate by direct transrectal injection
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ZUCKIER, L. S., FINKELSTEIN, M., KREUTZER, E. R., STONE, P. L., FREED, S. Z., BARD, R. H., BLAUFOX, and FREEMAN, L. M.
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- 1990
42. Electronics for the BaBar Central Drift Chamber
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Albert, J., Bajic, A., Bard, R., Beaulieu, M., Blinov, V., Boyarski, A., Broomer, B., Coupal, D., Dal Corso, F., Dolinsky, S., Dorfan, D., Dow, S., Dubrovin, M., Dusatko, J., Erdos, E., Faccini, R., Fernandez, J.P., Ford, W.T., Galeazzi, F., Haller, G., Innes, W., Jawahery, A., Kreig, H., Lankford, A.J., Levi, M., von der Lippe, H., MacFarlane, D.B., Martin, J.-P., Momayezi, M., Morandin, M., Morii, M., Nelson, D., Nguyen, P., Palrang, M., Roy, J., Sadrozinski, H., Schumm, B., Sciolla, G., Seiden, A., Smith, A.J.S., Spencer, E., Soha, A., Taras, P., Varnes, E., Weinstein, A., Wilson, F., and Yushkov, A.
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Fiber optic networks -- Research ,Fiber optics -- Research ,Cosmic rays -- Analysis ,Detector circuits (Telecommunications) -- Research ,Business ,Electronics ,Electronics and electrical industries - Abstract
The central drift chamber for the BaBar detector at the SLAC B-factory is based on a hexagonal cell design with 7104 cells arranged in 40 layers and drift gas Helium:isobutane (80%:20%). Performance optimization and integration requirements led to an electronics design that mounts the amplifier-discriminator and digitizing circuitry directly on the endplate. High channel density is achieved using a 4-channel custom amplifier-discriminator IC and an 8-channel custom CMOS TDC/FADC IC on a single circuit board. Data read from the front ends are multiplexed on 4 fiber optic links, and prompt trigger data are sent out continuously on 24 links. Analysis of cosmic ray data demonstrates that the electronics design meets the performance goals for the BaBar drift chamber. The final electronics were installed on the drift chamber in July, 1998. Installation of BaBar on beamline is scheduled for March, 1999.
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- 1999
43. Persistent pulmonary pathology after COVID-19 is associated with high viral load, weak antibody response, and high levels of matrix metalloproteinase-9
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Tøri Vigeland Lerum, Niklas Nyboe Maltzahn, Pål Aukrust, Marius Trøseid, Katerina Nezvalova Henriksen, Trine Kåsine, Anne-Ma Dyrhol-Riise, Birgitte Stiksrud, Mette Haugli, Bjørn Blomberg, Bård Reiakvam Kittang, Asgeir Johannessen, Raisa Hannula, Saad Aballi, Anders Benjamin Kildal, Ragnhild Eiken, Tuva Børresdatter Dahl, Fridtjof Lund-Johansen, Fredrik Müller, Jezabel Rivero Rodriguez, Carin Meltzer, Gunnar Einvik, Thor Ueland, Inge Christoffer Olsen, NOR-SOLIDARITY Consortium, Andreas Barratt-Due, Trond Mogens Aaløkken, and Ole Henning Skjønsberg
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Medicine ,Science - Abstract
Abstract The association between pulmonary sequelae and markers of disease severity, as well as pro-fibrotic mediators, were studied in 108 patients 3 months after hospital admission for COVID-19. The COPD assessment test (CAT-score), spirometry, diffusion capacity of the lungs (DLCO), and chest-CT were performed at 23 Norwegian hospitals included in the NOR-SOLIDARITY trial, an open-labelled, randomised clinical trial, investigating the efficacy of remdesivir and hydroxychloroquine (HCQ). Thirty-eight percent had a CAT-score ≥ 10. DLCO was below the lower limit of normal in 29.6%. Ground-glass opacities were present in 39.8% on chest-CT, parenchymal bands were found in 41.7%. At admission, low pO2/FiO2 ratio, ICU treatment, high viral load, and low antibody levels, were predictors of a poorer pulmonary outcome after 3 months. High levels of matrix metalloproteinase (MMP)-9 during hospitalisation and at 3 months were associated with persistent CT-findings. Except for a negative effect of remdesivir on CAT-score, we found no effect of remdesivir or HCQ on long-term pulmonary outcomes. Three months after hospital admission for COVID-19, a high prevalence of respiratory symptoms, reduced DLCO, and persistent CT-findings was observed. Low pO2/FiO2 ratio, ICU-admission, high viral load, low antibody levels, and high levels of MMP-9 were associated with a worse pulmonary outcome.
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- 2021
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44. Abstracts from The Cold Weather Operations Conference 2021
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Arne Johan Norheim, Bård Rannestad, Richard Howes, Erling Bekkestad Rein, Ellen Jørum, Karl Friedl, George Havenith, Hilde Kristin Teien, James Brian Mercer, Jørgen Melau, Louis de Weerd, Michael Smith, Natalie Taylor, Øyvind Albert Voie, Pål Bergan-Skar, Steve Andrews, Torvind Næsheim, and Tuva Steinberg
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Cold weather injury ,freezing cold injury ,hypothermia ,military ,snow avalanche ,non-freezing cold injury ,Arctic medicine. Tropical medicine ,RC955-962 - Abstract
A common effort for both military and civil healthcare is to achieve knowledge-based health care in cold weather injuries and fatal accidents in harsh arctic environment. The Cold Weather Operations Conference in November 2021, having more than 300 participants from 20 countries, was addressing the prevention and treatment of injuries and trauma care in cold weather conditions and the challenges for military prehospital casualty care. The intention of the programme was to stimulate further research and systematic knowledge-based clinical work. The abstracts from the conference present cold weather research and clinical experience relevant for readers of the International Journal of Circumpolar Health.
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- 2022
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45. SARS CoV-2 Infection among Health Care Workers from Different Health Care Facilities in Western Norway: A Prospective, Cross-Sectional Study
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Bård Reiakvam Kittang, Bjørn Blomberg, Marianne Sævik, Jan Stefan Olofsson, Bergen COVID-19 Research Group, Nina Langeland, and Rebecca Jane Cox
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COVID-19 ,SARS-CoV-2 antibodies ,HCW ,PPE ,Microbiology ,QR1-502 - Abstract
Background: Comparative data on COVID-19 among health care workers (HCWs) in different health care settings are scarce. This study investigated the rates of previous COVID-19 among HCWs in nursing homes, hospitals and a municipal emergency room (ER). Methods: We prospectively included 747 HCWs: 313 from nursing homes, 394 from hospitals and 40 from the ER. The diagnosis of COVID-19 was based on serological evidence of SARS-CoV-2 antibody positivity and self-reported RT-PCR positivity prior to inclusion. Information regarding age, sex and exposure to SARS-CoV-2 infection was collected. Results: A total of 4% (11/313) of nursing home HCWs and 6% (28/434) of HCWs in hospitals/the ER tested positive by serology and/or RT-PCR (p = 0.095). Fewer HCWs in nursing homes had occupational exposure to SARS-CoV-2 compared to those in hospitals/the ER (16% vs. 48%, p < 0, 001), but nursing homes had a higher proportion of HCWs with occupational exposure using partial/no PPE (56% vs. 19%, p < 0.001). Nevertheless, no significant differences in the risk for COVID-19 were found in relation to the rate of occupational exposure (p = 0.755) or use of inadequate PPE (p = 0.631). Conclusions: Despite a small sample size, the risk for COVID-19 among HCWs did not appear to be related to the type of health care facility, rates of occupational exposure or use of PPE.
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- 2022
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46. Neurogenic overactive bladder in spinal cord injury and multiple sclerosis: role of onabotulinumtoxinA.
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Ethans, K. D., Casey, A. R., Bard, R. J., and Namaka, M. P.
- Subjects
OVERACTIVE bladder ,QUALITY of life ,MULTIPLE sclerosis ,SPINAL cord injuries ,BOTULINUM toxin ,PATIENTS - Abstract
People with neurogenic overactive bladder from either multiple sclerosis or spinal cord injury often suffer significant morbidity and decreased quality of life. Here we review the pathophysiology of neurogenic overactive bladder and the impact it can have on people with multiple sclerosis or spinal cord injury. We also address the various traditional treatment options and focus on the use of botulinum toxin A (specifically onabotulinumtoxinA) for this condition. [ABSTRACT FROM AUTHOR]
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- 2014
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47. Emerging Threat of Antimicrobial Resistance in β-Hemolytic Streptococci
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Oddvar Oppegaard, Steinar Skrede, Haima Mylvaganam, and Bård Reiakvam Kittang
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β-hemolytic streptococci ,antimicrobial resistance ,Streptococcus dysgalactiae ,Streptococcus pyogenes ,Streptococcus agalactiae ,Microbiology ,QR1-502 - Abstract
Highly variable resistance rates to erythromycin and clindamycin have been reported in the β-hemolytic streptococcal species Streptococcus pyogenes, Streptococcus agalactiae, and Streptococcus dysgalactiae, depending on geographic and temporal context. In the present study we aimed to examine the longitudinal trends of antimicrobial resistance in these three species in a northern European setting. Furthermore, we used whole genome sequencing to identify resistance determinants and the mobile genetic elements involved in their dissemination, as well as elucidate phylogenetic relationships. All cases of invasive β-hemolytic streptococcal diseases in Health Region Bergen, western Norway, in the period 2004 to 2018 were retrospectively identified, comprising 271, 358, and 280 cases of S. pyogenes, S. agalactiae, and S. dysgalactiae, respectively. Antimicrobial susceptibility testing revealed a gradual but significant increase in erythromycin and clindamycin resistance for S. agalactiae and S. dysgalactiae during the study period. Whole genome sequencing of the erythromycin and clindamycin resistant bacterial population revealed a substantial phylogenetic diversity in S. agalactiae and S. dysgalactiae. However, the mobile genetic elements harboring the resistance determinants showed remarkable intra- and interspecies similarities, suggesting a dissemination of antimicrobial resistance predominantly through conjugative transfer rather than clonal expansion of resistant strains in these two species. Conversely, antimicrobial resistance in S. pyogenes remained low, apart from a transient outbreak of a clindamycin and erythromycin resistant emm11/ST403-clone in 2010–2012. Increased epidemiological attentiveness is warranted to monitor the emerging threat of antimicrobial resistance in β-hemolytic streptococci, particularly in S. agalactiae and S. dysgalactiae.
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- 2020
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48. Exploring the arthritogenicity of Streptococcus dysgalactiae subspecies equisimilis
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Oddvar Oppegaard, Haima Mylvaganam, Steinar Skrede, and Bård Reiakvam Kittang
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Streptococcus dysgalactiae Subspecies equisimilis ,Group C streptococcus ,Group G streptococcus ,Osteoarticular infections ,Septic arthritis ,Tissue tropism ,Microbiology ,QR1-502 - Abstract
Abstract Background During the past decades, Streptococcus dysgalactiae subspecies equisimilis (SDSE) has been increasingly recognized as an important human pathogen. Osteoarticular infections is one of the predominant disease manifestations of SDSE, but the pathogenetic rationale for its arthritogenicity has yet to be unravelled. We aimed to explore if the rising incidence of osteoarticular infections caused by this pathogen in our region emanated from clonal expansion of strains with enhanced tropism for bone and joint tissue components or orthopaedic implants. Results Twenty-nine SDSE-isolates associated with osteoarticular infections were retrospectively identified. Their genomic content and affinity for fibronectin, collagen and stainless steel were compared to 24 temporally and geographically matched SDSE blood culture isolates obtained from patients without bone or joint infections. Despite a thorough genetic and phenotypic dissection, neither the presence or absence of any single gene, nor the binding abilities of the SDSE isolates, were predictive of clinical entity. SNP analysis revealed a heterogenous population, and a correlation between phylogenetic relationships and disease manifestation was not evident. However, we identified a strong concordance between phenotypic binding abilities and genetic variations in the pilus-region, also denoted as the FCT-region (Fibronectin binding, Collagen binding and T-antigen). This observation could be related to the ample and varied repertoire of putative adhesins residing within this region, including proteins predicted to adhere to fibronectin and collagen, as well as fibrinogen. Conclusions SDSE strains associated with osteoarticular infections do not emanate from subpopulation characterized by distinct genetic or phenotypic traits. The genetic architecture of the pilus region was predictive of the adhesive properties of the SDSE-isolates, but its role in tissue tropism needs further investigation. To the best of our knowledge, this is the first comprehensive characterization of the genetic landscape of the SDSE pilus region.
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- 2018
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49. Carbohydrate Binding Macromolecules in Intraspecific Marine Microbial Associations.
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Iman, S., Bard, R., and Tosteson, T.
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- 1981
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50. Pharmacological Activity of High Molecular Weight Micro-Algal Exudates.
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Galarza, J., Revuelta, R., Zaidi, B., Bard, R., and Tosteson, T.
- Published
- 1981
- Full Text
- View/download PDF
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